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Anaesthetic gases and the environment: Is it time for a rethink? 麻醉气体与环境:是时候重新思考了吗?
IF 2.3 4区 医学 Q2 SURGERY Pub Date : 2024-08-01 DOI: 10.1016/j.surge.2024.04.014

Background

General anaesthesia is in common use for patients undergoing surgical procedures, with the option of both inhalational and intravenous anaesthetic techniques. Anaesthetic gases are often excluded from discussions on sustainable healthcare delivery, despite being a significant contributor to the overall environmental impact of healthcare services.

Methods

A literature review was carried out on previously published papers on the impact anaesthetic gases have on our environment and at ways to reduce their impact in current anaesthetic practice. The aim was to write a narrative review detailing the areas of concern as well as the current clinical situation in the European setting.

Summary/conclusions

The two classes of inhaled anaesthetic agent most frequently used are nitrous oxide and volatile agents (most commonly sevoflurane, isoflurane and desflurane). Both are recognised greenhouse gases that contribute to climate change.

Minor modifications in the use of anaesthetic gases can have a significant environmental impact. These modifications include avoiding nitrous oxide whenever possible, avoiding desflurane (and using sevoflurane instead), using low flow anaesthesia during maintenance, swapping volatile-based anaesthesia for a TIVA technique when clinically appropriate and considering the use of central neuraxial or regional anaesthesia in place of general anaesthesia when possible.

背景:接受外科手术的患者通常会进行全身麻醉,并可选择吸入和静脉麻醉技术。尽管麻醉气体对医疗保健服务的整体环境影响很大,但在有关可持续医疗保健服务的讨论中,麻醉气体往往被排除在外:方法:我们对以前发表的关于麻醉气体对环境的影响以及在当前麻醉实践中减少其影响的方法的论文进行了文献综述。目的是撰写一篇叙事性综述,详细说明关注的领域以及欧洲目前的临床情况:最常用的两类吸入麻醉剂是氧化亚氮和挥发性麻醉剂(最常见的是七氟醚、异氟醚和地氟醚)。这两种物质都是公认的温室气体,会导致气候变化。在使用麻醉气体时稍作调整,就能对环境产生重大影响。这些调整包括尽可能避免使用氧化亚氮、避免使用地氟醚(而使用七氟醚)、在维持过程中使用低流量麻醉、在临床合适的情况下将挥发性麻醉改为 TIVA 技术,以及在可能的情况下考虑使用中枢神经或区域麻醉来代替全身麻醉。
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引用次数: 0
Environmentally sustainable kidney care through transplantation: Current status and future challenges 通过移植实现环境可持续的肾脏护理:现状与未来挑战
IF 2.3 4区 医学 Q2 SURGERY Pub Date : 2024-08-01 DOI: 10.1016/j.surge.2024.01.001

The environmental impact of healthcare is an issue currently examined with increased scrutiny and on a global scale with multiple stakeholders seeking to identify the appropriate interventions to reduce it. Interestingly, a significant portion of healthcare's environmental impact stems from intensive modalities of treatment for chronic disease. There is no better example than End-Stage Renal Disease (ESRD), where dialysis or transplantation are the modalities of treatment offered to the vast majority of these patients. Kidney transplantation (KTx) offers a longer life expectancy and improved quality of life in comparison to dialysis. Cost-effectiveness analyses have proven its financial superiority, as well. PubMed and EMBASE literature search using keywords “kidney transplantation”, “carbon footprint”, “sustainability” showed that there is no published work in the field of environmental sustainability in kidney transplantation. Relevant literature was identified for surgical services and applied to transplantation. Assuming its environmental superiority to dialysis, maximising KTx rate would be an important action towards “green” renal care services. That could be achieved through living organ donation, systematic use of machine perfusion for extended criteria deceased donors and individualised immune risk stratification techniques. All these measures aim towards implementing enhanced recovery protocols and two vital steps can be taken towards assessing their value. The first step is a detailed audit of the environmental impact of these novel techniques and secondly their impact in reducing the length of hospital stay and its subsequent environmental impact. Another key element is delivering appropriate post-operative care, substituting allograft biopsy with non-invasive techniques and reducing physical outpatient follow-up, using telemedicine. The gap in quantifying KTx services environmental impact needs to be addressed urgently, with development of strategies within the multidisciplinary transplant team. Introducing novel technologies can lead to donor pool expansion and improved organ utilisation rates, transforming transplant services in “green” hubs.

医疗保健对环境的影响是一个目前在全球范围内越来越受到关注的问题,多个利益相关方都在寻求适当的干预措施来减少对环境的影响。有趣的是,医疗保健对环境的影响很大一部分源于慢性病的密集治疗方式。最好的例子莫过于终末期肾病(ESRD),透析或移植是绝大多数患者的治疗方式。与透析相比,肾移植(KTx)能延长患者的预期寿命,提高生活质量。成本效益分析也证明了其经济上的优越性。使用关键词 "肾移植"、"碳足迹"、"可持续发展 "在 PubMed 和 EMBASE 上进行文献检索,结果显示在肾移植的环境可持续发展领域还没有公开发表的文献。我们找到了外科服务的相关文献,并将其应用到移植手术中。假设肾移植在环境方面优于透析,那么最大限度地提高肾移植率将是实现 "绿色 "肾脏护理服务的重要行动。这可以通过活体器官捐献、系统性地使用机器灌注延长已故捐献者的标准以及个性化的免疫风险分层技术来实现。所有这些措施都旨在实施强化的恢复方案,可以采取两个重要步骤来评估其价值。第一步是详细审核这些新技术对环境的影响,第二步是审核它们对缩短住院时间及其对环境的影响。另一个关键因素是提供适当的术后护理,用无创技术替代异体移植活检,利用远程医疗减少门诊随访。在量化 KTx 服务对环境的影响方面存在差距,亟需通过在多学科移植团队内部制定战略来加以解决。引进新技术可以扩大供体库,提高器官利用率,从而改变 "绿色 "中心的移植服务。
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引用次数: 0
An assessment of sustainable transport infrastructure in a national healthcare system 对国家医疗体系中可持续交通基础设施的评估。
IF 2.3 4区 医学 Q2 SURGERY Pub Date : 2024-08-01 DOI: 10.1016/j.surge.2023.10.008

Introduction

Healthcare contributes significantly to carbon dioxide emissions, which can be reduced by promoting sustainable mobility amongst staff commuting. This study aims to investigate the national sustainable transport infrastructure for staff of healthcare facilities and utilise this data to develop a novel scoring and ranking system.

Methods

This was an empirical retrospective observational study. Data was collected on all 47 hospitals sustainable transport infrastructure. A working group calculated the weighted scores for each sustainable transport data point. These scores were used to calculate the Total and Active Sustainability Scores for each hospital, allowing a ranking to be formed.

Results

7 of 47 (15 %) hospitals had EV charging on campus. 17 of 47 (36 %) hospitals had secure bike parking. 2 of 47 (4 %) hospitals had a “bike hub”. 18 of 47 (38 %) hospitals had a bike lane. 13 of 22 (59 %) city hospitals had bike sharing facilities. 42 of 47 (89 %) hospitals had one public transport route. City hospitals ranked higher in both Total & Active Sustainability Scores.

Discussion

This study explored a new concept of measuring sustainable transport infrastructure. Frameworks examining sustainability are available, however, none allowed for ranking of hospitals. This study highlights the lack of both research in this field and sustainable transport infrastructure in hospitals.

简介:医疗保健对二氧化碳排放有很大贡献,可以通过促进员工通勤的可持续流动性来减少二氧化碳排放。本研究旨在调查医疗机构工作人员的国家可持续交通基础设施,并利用这些数据开发一个新的评分和排名系统。方法:这是一项经验回顾性观察研究。收集了所有47家医院可持续交通基础设施的数据。一个工作组计算了每个可持续交通数据点的加权分数。这些分数用于计算每家医院的总体和积极可持续性分数,从而形成排名。结果:47家医院中有7家(15%)在校园内进行电动汽车充电。47家医院中有17家(36%)有安全的自行车停车场。47家医院中有2家(4%)有“自行车中心”。47家医院中有18家(38%)有自行车道。22家城市医院中有13家(59%)拥有共享单车设施。47家医院中有42家(89%)有一条公共交通路线。城市医院在总体和积极可持续性得分中排名较高。讨论:本研究探索了衡量可持续交通基础设施的新概念。然而,研究可持续性的框架是可用的,不允许对医院进行排名。这项研究强调了这一领域的研究和医院可持续交通基础设施的缺乏。
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引用次数: 0
Retrospective case series of vertebral artery injuries associated with cervical spine trauma. 与颈椎创伤相关的椎动脉损伤回顾性病例系列。
IF 2.3 4区 医学 Q2 SURGERY Pub Date : 2024-07-30 DOI: 10.1016/j.surge.2024.07.007
Leah Morris, Anna Lawless, Jake M McDonnell, Kielan V Wilson, Harry Marland, Stacey Darwish, Joseph S Butler

Background: Vertebral artery injuries (VAI) can occur due to cervical spine trauma. VAI can prove a serious complication and potentially compromise vascular supply to the posterior aspect of the brain. Currently, there is a paucity of evidence with regards to incidence, management, and outcomes for these patients. The purpose of this study is to investigate and elucidate the incidence of VAI associated with cervical trauma at a national tertiary referral centre for spinal pathology, their respective management, and associated outcomes.

Methods: A retrospective review was conducted from 2012 to 2021 to identify patients with VAI secondary to cervical spine trauma. Demographic, clinical, and radiological data was collected to identify common traits in injury characteristics and management.

Results: 1013 spine patients presented to our institution across the 10-year period. 739/1013 (72.9 %) were trauma patients. 42/739 (5.7 %) were imaged for suspected VAI secondary to trauma. There were 14/739 (1.9 %) confirmed VAI. All patients had CT-angiography for diagnosis. Four of the confirmed VAI patients (28.6 %) had additional MR-angiography imaging. Right-side was the most common side of VAI injury (7/14; 50 %), followed by left (5/14; 35.7 %) and bilateral (2/14; 14.3 %) injuries. 8/14 (57.1 %) patients were prescribed anti-thrombotic therapy. Acute mortality within 3-months was noted to be 2/14 (14.3 %) and occurred at 49 days and 57 days respectively.

Conclusion: VAI associated with cervical spine injury is rare in occurrence. However, it can be associated with high morbidity and mortality. As such, a multi-disciplinary approach to care is integral to ensuring good outcomes in these patients.

背景:颈椎创伤可导致椎动脉损伤(VAI)。椎动脉损伤是一种严重的并发症,有可能危及大脑后部的血管供应。目前,有关这类患者的发病率、管理和预后的证据还很少。本研究旨在调查和阐明一家国家级脊柱病理三级转诊中心与颈椎创伤相关的 VAI 发病率、各自的处理方法和相关结果:方法: 对 2012 年至 2021 年期间的病例进行回顾性分析,以确定因颈椎创伤而继发 VAI 的患者。我们收集了人口统计学、临床和放射学数据,以确定损伤特征和治疗的共同特点:结果:在这 10 年间,共有 1013 名脊柱患者到我院就诊。739/1013(72.9%)为外伤患者。42/739(5.7%)的患者因怀疑继发于外伤而接受了 VAI 检查。14/739(1.9%)人确诊为 VAI。所有患者都进行了 CT 血管造影诊断。在确诊的 VAI 患者中,有 4 人(28.6%)接受了额外的 MR 血管造影检查。右侧是最常见的 VAI 损伤侧(7/14;50%),其次是左侧(5/14;35.7%)和双侧(2/14;14.3%)。8/14(57.1%)名患者接受了抗血栓治疗。3个月内的急性死亡率为2/14(14.3%),分别发生在49天和57天:结论:与颈椎损伤相关的 VAI 很少发生。结论:与颈椎损伤相关的 VAI 发生率很低,但发病率和死亡率却很高。因此,多学科的护理方法是确保这些患者获得良好疗效不可或缺的因素。
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引用次数: 0
The impact of disability on recruitment to higher surgical specialty training: A retrospective cohort study. 残疾对高等外科专业培训招生的影响:一项回顾性队列研究。
IF 2.3 4区 医学 Q2 SURGERY Pub Date : 2024-07-30 DOI: 10.1016/j.surge.2024.07.006
Ricky Ellis, Yasin Al-Tawarah, Peter A Brennan, Amanda J Lee, John Hines, Duncan Sg Scrimgeour, Jennifer Cleland

Background: UK examining bodies are required to eliminate discrimination against people with protected characteristics. To achieve this in surgery, differential attainment (DA) in assessments used as gatekeepers to career progression must be ruled out. This study investigated the impact of disability status on the likelihood of success at national selection for Higher Surgical Training (HST).

Methods: A retrospective cohort study of all UK graduates in the UKMED database (https://www.ukmed.ac.uk) who underwent selection for HST (ST3) from 2012 to 2019 (n = 2875). Univariate analysis identified differences in success rates at first-application. Logistic regression models identified whether disability was a predictor of success after adjusting for sociodemographic factors and prior MRCS performance.

Results: There was no significant difference in success rates between candidates with and without disabilities (all p > 0.05) for any surgical specialty. Disability status was not a statistically significant predictor of success. Female candidates were 25 % more likely to be successful (OR 1.25 [95%CI 1.05 to 1.49]) and Non-White candidates were 20 % less likely to be successful (OR 0.80 [95%CI 0.68 to 0.96]). Candidates who passed MRCS Part A and Part B at the first attempt were 49 % (OR 1.49 [95%CI 1.25 to 1.77]) and 90 % (OR 1.90 [95%CI 1.58 to 2.28]) more likely to be successful.

Conclusion: No significant difference was found in the likelihood of being successful at HST selection for any surgical specialty between applicants with and without disabilities, regardless of type of disability. DA was identified between other sociodemographic groups which requires further exploration.

背景:英国考试机构必须消除对受保护特征人群的歧视。要在外科领域实现这一目标,就必须在作为职业晋升门槛的评估中排除差异化成绩(DA)。本研究调查了残疾状况对成功通过国家高级外科培训(HST)选拔的可能性的影响:回顾性队列研究的对象是英国医学发展数据库(https://www.ukmed.ac.uk)中所有在2012年至2019年期间接受高等外科培训(ST3)选拔的英国毕业生(n = 2875)。单变量分析确定了首次申请成功率的差异。逻辑回归模型确定了在调整社会人口因素和之前的 MRCS 成绩后,残疾是否是成功的预测因素:结果:在任何外科专业中,有残疾和无残疾候选人的成功率都没有明显差异(均 p > 0.05)。残疾状况对成功率的预测没有统计学意义。女性考生的成功率要高 25%(OR 1.25 [95%CI 1.05 至 1.49]),而非白人考生的成功率要低 20%(OR 0.80 [95%CI 0.68 至 0.96])。首次通过 MRCS A 部分和 B 部分考试的考生成功的可能性分别为 49% (OR 1.49 [95%CI 1.25 to 1.77])和 90% (OR 1.90 [95%CI 1.58 to 2.28]):结论:无论残疾类型如何,有残疾和无残疾的申请者在成功通过HST外科专科遴选的可能性方面均无明显差异。在其他社会人口组别之间也发现了DA,这需要进一步探讨。
{"title":"The impact of disability on recruitment to higher surgical specialty training: A retrospective cohort study.","authors":"Ricky Ellis, Yasin Al-Tawarah, Peter A Brennan, Amanda J Lee, John Hines, Duncan Sg Scrimgeour, Jennifer Cleland","doi":"10.1016/j.surge.2024.07.006","DOIUrl":"https://doi.org/10.1016/j.surge.2024.07.006","url":null,"abstract":"<p><strong>Background: </strong>UK examining bodies are required to eliminate discrimination against people with protected characteristics. To achieve this in surgery, differential attainment (DA) in assessments used as gatekeepers to career progression must be ruled out. This study investigated the impact of disability status on the likelihood of success at national selection for Higher Surgical Training (HST).</p><p><strong>Methods: </strong>A retrospective cohort study of all UK graduates in the UKMED database (https://www.ukmed.ac.uk) who underwent selection for HST (ST3) from 2012 to 2019 (n = 2875). Univariate analysis identified differences in success rates at first-application. Logistic regression models identified whether disability was a predictor of success after adjusting for sociodemographic factors and prior MRCS performance.</p><p><strong>Results: </strong>There was no significant difference in success rates between candidates with and without disabilities (all p > 0.05) for any surgical specialty. Disability status was not a statistically significant predictor of success. Female candidates were 25 % more likely to be successful (OR 1.25 [95%CI 1.05 to 1.49]) and Non-White candidates were 20 % less likely to be successful (OR 0.80 [95%CI 0.68 to 0.96]). Candidates who passed MRCS Part A and Part B at the first attempt were 49 % (OR 1.49 [95%CI 1.25 to 1.77]) and 90 % (OR 1.90 [95%CI 1.58 to 2.28]) more likely to be successful.</p><p><strong>Conclusion: </strong>No significant difference was found in the likelihood of being successful at HST selection for any surgical specialty between applicants with and without disabilities, regardless of type of disability. DA was identified between other sociodemographic groups which requires further exploration.</p>","PeriodicalId":49463,"journal":{"name":"Surgeon-Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141861387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Innovative use of TXA and protamine-infused hydrogels to reduce postoperative bleeding in breast surgery for heparin-anticoagulated patients "创新性地使用注入 TXA 和原胺的水凝胶来减少肝素抗凝患者乳房手术的术后出血"。
IF 2.3 4区 医学 Q2 SURGERY Pub Date : 2024-07-22 DOI: 10.1016/j.surge.2024.07.002
{"title":"Innovative use of TXA and protamine-infused hydrogels to reduce postoperative bleeding in breast surgery for heparin-anticoagulated patients","authors":"","doi":"10.1016/j.surge.2024.07.002","DOIUrl":"10.1016/j.surge.2024.07.002","url":null,"abstract":"","PeriodicalId":49463,"journal":{"name":"Surgeon-Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141753211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The place of splenectomy in the therapeutic management of patients with infective endocarditis and splenic abscess: A single center experience and a literature review. 脾切除术在感染性心内膜炎和脾脓肿患者治疗中的地位:单中心经验与文献综述。
IF 2.3 4区 医学 Q2 SURGERY Pub Date : 2024-07-18 DOI: 10.1016/j.surge.2024.06.008
Corina-Elena Minciuna, Beatrice Tivadar, Vlad Costin Ilie, Ruxandra Daniela Fota, Alina Teodora Timisescu, Vlad Anton Iliescu, Ioan Mircea Coman, Gabriela Droc, Andrei George Iosifescu, Catalin Vasilescu

Introduction: Infective endocarditis(IE) has a low incidence, but it remains a serious disease with high mortality rates. Only 5 % of these patients will develop a splenic abscess, and the number of patients that have IE and a splenic abscess requiring surgery is low. The current guidelines recommend that splenectomy should be performed prior to valve replacement, but there is no strong evidence to support this statement and no evidence to clearly endorse the order in which the surgical interventions should be performed. The objective of this review and case series is to establish the proper treatment strategy, to assess the adequate order of the surgical interventions and to clarify the role of percutaneous drainage in the management of these patients.

Material and methods: All patients with infective endocarditis and splenic abscess who underwent surgery in our institution, between January 2008 and December 2020 were included in this study, excluding patients which had cardiac device related endocarditis. Literature review on the matter included a number of 30 studies which were selected from the PubMed database.

Results: Assessing the literature and case series no reinfection was reported for simultaneously performing splenectomy(S) and valvular surgery(VS) nor for VS followed by S.

Conclusion: Percutaneous drainage of the splenic abscesses is a feasible solution as definitive therapy in high-risk patients or as bridge therapy. Additional studies are needed, even though they are difficult to conduct, therefore a national/international infectious endocarditis register may be of use to clarify these challenges.

导言:感染性心内膜炎(IE)的发病率很低,但仍是一种死亡率很高的严重疾病。感染性心内膜炎患者中只有5%会发展为脾脓肿,因此需要手术治疗的感染性心内膜炎和脾脓肿患者人数很少。目前的指南建议应在瓣膜置换术前进行脾切除术,但没有有力的证据支持这一说法,也没有证据明确认可手术干预的顺序。本综述和病例系列旨在确定正确的治疗策略,评估手术干预的适当顺序,并明确经皮引流在这些患者治疗中的作用:本研究纳入了2008年1月至2020年12月期间在我院接受手术治疗的所有感染性心内膜炎和脾脓肿患者,但不包括与心脏设备相关的心内膜炎患者。相关文献综述包括从 PubMed 数据库中选取的 30 项研究:结果:通过对文献和病例系列的评估,没有发现同时进行脾切除术(S)和瓣膜手术(VS)或先进行VS再进行S的再感染病例:结论:脾脓肿经皮引流术是一种可行的方法,可作为高危患者的最终治疗或过渡治疗。尽管难以开展,但仍需进行更多的研究,因此,全国性/国际性的感染性心内膜炎登记册可能有助于澄清这些难题。
{"title":"The place of splenectomy in the therapeutic management of patients with infective endocarditis and splenic abscess: A single center experience and a literature review.","authors":"Corina-Elena Minciuna, Beatrice Tivadar, Vlad Costin Ilie, Ruxandra Daniela Fota, Alina Teodora Timisescu, Vlad Anton Iliescu, Ioan Mircea Coman, Gabriela Droc, Andrei George Iosifescu, Catalin Vasilescu","doi":"10.1016/j.surge.2024.06.008","DOIUrl":"https://doi.org/10.1016/j.surge.2024.06.008","url":null,"abstract":"<p><strong>Introduction: </strong>Infective endocarditis(IE) has a low incidence, but it remains a serious disease with high mortality rates. Only 5 % of these patients will develop a splenic abscess, and the number of patients that have IE and a splenic abscess requiring surgery is low. The current guidelines recommend that splenectomy should be performed prior to valve replacement, but there is no strong evidence to support this statement and no evidence to clearly endorse the order in which the surgical interventions should be performed. The objective of this review and case series is to establish the proper treatment strategy, to assess the adequate order of the surgical interventions and to clarify the role of percutaneous drainage in the management of these patients.</p><p><strong>Material and methods: </strong>All patients with infective endocarditis and splenic abscess who underwent surgery in our institution, between January 2008 and December 2020 were included in this study, excluding patients which had cardiac device related endocarditis. Literature review on the matter included a number of 30 studies which were selected from the PubMed database.</p><p><strong>Results: </strong>Assessing the literature and case series no reinfection was reported for simultaneously performing splenectomy(S) and valvular surgery(VS) nor for VS followed by S.</p><p><strong>Conclusion: </strong>Percutaneous drainage of the splenic abscesses is a feasible solution as definitive therapy in high-risk patients or as bridge therapy. Additional studies are needed, even though they are difficult to conduct, therefore a national/international infectious endocarditis register may be of use to clarify these challenges.</p>","PeriodicalId":49463,"journal":{"name":"Surgeon-Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141724888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gender more than ethnicity or disability influences the choice of a career in cardiothoracic surgery by United Kingdom medical students 性别比种族或残疾更能影响英国医科学生对心胸外科职业的选择。
IF 2.3 4区 医学 Q2 SURGERY Pub Date : 2024-07-18 DOI: 10.1016/j.surge.2024.06.002

Objectives

Cardiothoracic surgery has reported poor equality, diversity, and inclusion amongst its faculty [1–3]. We explored how gender, ethnicity, and disability influence medical students’ interest in cardiothoracic surgery as a career choice, as well as overall exposure to cardiothoracic surgery in the undergraduate curriculum.

Methods

We distributed a 26-item Google Forms online survey to student members of a medical education group from all 37 UK medical schools via social media. Respondents were asked to rank different ‘factors of interest’ on a 1–5 Likert scale (1 ​= ​not important at all, 5 ​= ​very important) and were encouraged to add free-text comments. Quantitative data were analysed using SPSS.

Results

There were 258 respondents, 62% identifying as female and 38% male. Respondents' ethnicities were 45% White, 44% Asian or Asian British, and 11% from other ethnic groups. 11% of respondents confirmed ‘long-standing illness or disability’.

Men were almost twice as likely to consider a career in cardiothoracic surgery than women (33% vs 19%; p ​< ​0.001). Women were more likely than men to feel that their gender, lack of a similarly gendered mentor, and long working hours were important factors when considering cardiothoracic surgery as a career.

Ethnicity of the respondent did not appear to affect how they perceived the challenges of a career in cardiothoracic surgery. Interestingly, ‘long-standing illness or disability’ did not significantly affect the decision making to consider this specialty as a career.

Overall, 73% of respondents reported not having adequate exposure to cardiothoracic surgery at medical school and agreed they would benefit from more time.

Conclusions

Female medical students felt their gender, lack of same-sex role models, and perceived long working hours were barriers in considering cardiothoracic surgery as a career. All students felt the need for more exposure to Cardiothoracic Surgery in the undergraduate curriculum.

目的:据报道,心胸外科的师资队伍在平等性、多样性和包容性方面存在不足[1-3]。我们探讨了性别、种族和残疾如何影响医学生对心胸外科学作为职业选择的兴趣,以及在本科课程中接触心胸外科学的总体情况:我们通过社交媒体向英国 37 所医学院的医学教育小组的学生成员发放了一份包含 26 个项目的谷歌表格在线调查。我们要求受访者用 1-5 级李克特量表(1 = 完全不重要,5 = 非常重要)对不同的 "关注因素 "进行排序,并鼓励他们添加自由文本评论。采用 SPSS 对定量数据进行了分析:共有 258 位受访者,其中 62% 为女性,38% 为男性。45% 的受访者为白人,44% 为亚裔或英国亚裔,11% 为其他族裔。11%的受访者确认 "长期患病或残疾"。男性考虑从事心胸外科工作的可能性几乎是女性的两倍(33% 对 19%;P 结论:男性考虑从事心胸外科工作的可能性是女性的两倍:女医科学生认为自己的性别、缺乏同性榜样以及认为工作时间长是她们考虑从事心胸外科的障碍。所有学生都认为有必要在本科课程中更多地接触心胸外科。
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引用次数: 0
Outcomes of perioperative intravenous iron infusion in femoral fracture surgery: A systematic review and meta-analysis of randomised controlled trials 股骨骨折手术围手术期静脉输注铁剂的结果:随机对照试验的系统回顾和荟萃分析。
IF 2.3 4区 医学 Q2 SURGERY Pub Date : 2024-07-14 DOI: 10.1016/j.surge.2024.07.005

Background

Patient blood management recommends the use of intravenous (IV) iron infusion to reduce inappropriate blood transfusion perioperatively for anaemic surgical patients. However, evidence regarding its use in urgent femoral fracture surgery is limited. This systematic review aims to collate the current evidence regarding the utilisation of IV iron in femoral fracture surgery.

Method

MEDLINE, Embase, Cochrane CENTRAL, Clinicaltrials.gov, and the WHO ICTRP databases were systematically searched for randomised controlled trials (RCT) comparing the outcomes of perioperative IV iron infusion with placebo in adults requiring surgical management for femoral fractures. Risk ratios (RR) were calculated using the Mantel-Haenszel method for dichotomous outcomes, and mean differences (MD) were calculated with the inverse-variance method for continuous outcomes.

Results

Six RCTs with 1292 patients were included. No statistically significant difference was found in the proportion of patients receiving red blood cell (RBC) transfusion (RR = 0.87, 95%CI: 0.75; 1.01, p = 0.058) between groups. Statistically significant difference in postoperative haemoglobin concentration was found between groups measured between day 4–7 of admission (MD = 1.93 g/L, 95%CI: 0.48; 3.39, p = 0.024), but not clinically significant. No statistically significant differences were found between groups in mortality rate, length of hospital stay, infection rate, or return to home rate.

Conclusion

Current evidence indicates that IV iron infusion alone does not provide any clinically significant benefit in femoral fracture surgery. Further high-quality RCTs are needed to explore its synergistic potential when used in combination with other perioperative optimisation methods, including tranexamic acid, erythropoietin and cell salvage.

背景:患者血液管理建议使用静脉输注铁剂,以减少贫血手术患者围手术期的不当输血。然而,在股骨骨折紧急手术中使用静脉输注的证据却很有限。本系统性综述旨在整理有关股骨骨折手术中静脉输注铁剂的现有证据:方法:系统检索了 MEDLINE、Embase、Cochrane CENTRAL、Clinicaltrials.gov 和 WHO ICTRP 数据库中的随机对照试验 (RCT),比较了股骨骨折需要手术治疗的成人围手术期静脉输注铁剂与安慰剂的疗效。对二分结果采用曼特尔-海恩泽尔法计算风险比(RR),对连续结果采用逆方差法计算平均差(MD):结果:共纳入六项研究,1292 名患者。各组间接受红细胞(RBC)输注的患者比例差异无统计学意义(RR=0.87,95%CI:0.75;1.01,P=0.058)。入院第 4-7 天测量的术后血红蛋白浓度在组间存在显著统计学差异(MD = 1.93 g/L,95%CI:0.48;3.39,p = 0.024),但无临床意义。在死亡率、住院时间、感染率或回家率方面,各组之间没有发现明显的统计学差异:结论:目前的证据表明,单纯静脉输注铁剂对股骨骨折手术并无任何临床意义。需要进一步开展高质量的研究性试验,以探索其与其他围手术期优化方法(包括氨甲环酸、促红细胞生成素和细胞抢救)联合使用时的协同潜力。
{"title":"Outcomes of perioperative intravenous iron infusion in femoral fracture surgery: A systematic review and meta-analysis of randomised controlled trials","authors":"","doi":"10.1016/j.surge.2024.07.005","DOIUrl":"10.1016/j.surge.2024.07.005","url":null,"abstract":"<div><h3>Background</h3><p><span><span>Patient blood management recommends the use of intravenous (IV) iron infusion to reduce inappropriate blood transfusion perioperatively for anaemic surgical patients. However, evidence regarding its use in urgent </span>femoral fracture surgery is limited. This </span>systematic review<span> aims to collate the current evidence regarding the utilisation of IV iron in femoral fracture surgery.</span></p></div><div><h3>Method</h3><p><span>MEDLINE, Embase, Cochrane CENTRAL, Clinicaltrials.gov, and the WHO ICTRP databases were systematically searched for </span>randomised controlled trials (RCT) comparing the outcomes of perioperative IV iron infusion with placebo in adults requiring surgical management for femoral fractures. Risk ratios (RR) were calculated using the Mantel-Haenszel method for dichotomous outcomes, and mean differences (MD) were calculated with the inverse-variance method for continuous outcomes.</p></div><div><h3>Results</h3><p><span>Six RCTs with 1292 patients were included. No statistically significant difference was found in the proportion of patients receiving red blood cell (RBC) transfusion (RR = 0.87, 95%CI: 0.75; 1.01, p = 0.058) between groups. Statistically significant difference in postoperative haemoglobin concentration was found between groups measured between day 4–7 of admission (MD = 1.93 g/L, 95%CI: 0.48; 3.39, p = 0.024), but not clinically significant. No statistically significant differences were found between groups in </span>mortality rate, length of hospital stay, infection rate, or return to home rate.</p></div><div><h3>Conclusion</h3><p><span>Current evidence indicates that IV iron infusion alone does not provide any clinically significant benefit in femoral fracture surgery. Further high-quality RCTs are needed to explore its synergistic potential when used in combination with other perioperative optimisation methods, including tranexamic acid, </span>erythropoietin and cell salvage.</p></div>","PeriodicalId":49463,"journal":{"name":"Surgeon-Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141621269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Distant lymph node metastasis in differentiated thyroid cancer: A population-based cohort study. 分化型甲状腺癌的远处淋巴结转移:基于人群的队列研究
IF 2.3 4区 医学 Q2 SURGERY Pub Date : 2024-07-11 DOI: 10.1016/j.surge.2024.07.004
Ying Ding, Ruixin Zhou

Background: Cervical lymph node metastasis (LNM) is the most common clinical event in patients with differentiated thyroid cancer (DTC). However, the incidence, pattern, treatment, and prognosis of distant LNM are yet to be reported.

Methods: DTC patients with distant LNM were identified from the Surveillance, Epidemiology, and End Results (SEER) database between 2016 and 2020. Multivariate models and propensity score matching (PSM) were used to account for the effects of covariates. The Kaplan-Meier method was used to evaluate the overall survival (OS) and cancer-specific survival (CSS). A nomogram was established to predict the probability of distant LNM in DTC patients, with calibration and Receiver Operating Characteristic (ROC) curves utilized to validate the nomogram's accuracy.

Results: Of the 42,339 DTC patients screened, 100 (0.24 %) patients presented with distant LNM. Risk factors including age, sex, T stage, N stage, bone metastasis, brain metastasis, and lung metastasis were included in the nomogram to predict the probability of distant LNM. The calibration curve of the nomogram was close to the ideal diagonal line and the area under the curve (AUC) of the ROC curve is 0.953. Distant LNM showed a worse prognosis after adjusting for confounders compared with non-distant LNM (P < 0.05). Remarkably, radioactive iodine (RAI) therapy did not improve the OS and CSS in DTC patients with distant LNM in the overall or PSM cohort.

Conclusions: Distant LNM presents as a comparatively rare but grave condition with a substantial negative impact on prognosis in patients with DTC. Identified risk factors of distant LNM are older age, male, advanced T stage and N stage, bone metastasis, brain metastasis, and lung metastasis. Remarkably, the current RAI therapy does not appear to significantly improve the survival outcome of DTC patients with distant LNM.

背景:颈淋巴结转移(LNM)是分化型甲状腺癌(DTC)患者最常见的临床症状。然而,关于远处淋巴结转移的发生率、模式、治疗和预后尚无报道:方法:从监测、流行病学和最终结果(SEER)数据库中找出2016年至2020年间患有远处LNM的DTC患者。采用多变量模型和倾向得分匹配(PSM)来考虑协变量的影响。采用卡普兰-梅耶法评估总生存期(OS)和癌症特异性生存期(CSS)。建立了预测 DTC 患者远处 LNM 概率的提名图,并利用校准和接收者操作特征曲线(ROC)验证提名图的准确性:在接受筛查的 42,339 名 DTC 患者中,有 100 人(0.24%)出现远处 LNM。包括年龄、性别、T期、N期、骨转移、脑转移和肺转移在内的风险因素被纳入提名图,以预测远处LNM的概率。提名图的校准曲线接近理想对角线,ROC 曲线的曲线下面积(AUC)为 0.953。与非远端 LNM 相比,调整混杂因素后,远端 LNM 的预后更差(P 结论:远端 LNM 的预后更差:远处 LNM 比较罕见,但病情严重,对 DTC 患者的预后有很大的负面影响。已确定的远处淋巴结转移风险因素包括年龄较大、男性、T 期和 N 期晚期、骨转移、脑转移和肺转移。值得注意的是,目前的 RAI 治疗似乎并不能明显改善伴有远处 LNM 的 DTC 患者的生存预后。
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Surgeon-Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
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