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Evaluating the role of preemptive intravenous ketorolac in preventing post-operative pain in patients undergoing hemorrhoidectomy: A randomized clinical trial. 评估先发制人静脉注射酮罗拉酸在预防痔疮切除术患者术后疼痛中的作用:一项随机临床试验。
IF 2.3 4区 医学 Q2 SURGERY Pub Date : 2025-12-11 DOI: 10.1016/j.surge.2025.11.008
Mohammad Dehbozorgi, Hooman Rezaei, Maryam Shahbazi, Kimia Falamarzi

Background: Post-hemorrhoidectomy pain remains a common and distressing factor that negatively affects the patient's recovery and satisfaction following the operation. Preemptive analgesia is a therapeutic measure before surgery initiation to prevent central sensitization and reduce the postoperative pain in the early period.

Objective: To evaluate the preemptive effect of intravenous ketorolac on pain severity in patients post-hemorrhoidectomy.

Methods: In this randomized clinical trial, 61 adults scheduled for hemorrhoidectomy were allocated to receive either 30 mg intravenous ketorolac just before induction (intervention group) or no preemptive analgesic (control). Both groups received postoperative pethidine as needed for breakthrough pain. Pain severity was assessed at 1 and 4 h postoperatively using the verbal rating scale (VRS), and postoperative opioid consumption was recorded.

Results: 32 out of 61 patients were enrolled in the intervention group and 29 in the control group. There was no difference in age or sex between the two groups (p > 0.05). The results showed that pain severity in the 1st and 4th hours after the operation was significantly lower in the intervention group (p < 0.001). Also, the postoperative demand for opioids was significantly lower in the intervention group (p = 0.002).

Conclusion: We found that NSAIDs, particularly ketorolac, can be used as preemptive medication to reduce postoperative pain and decrease the use of opioids. This might lead to a decrease in the side effects of opioids. However, further evaluations with larger populations and longer follow-up periods are essential. This randomized clinical trial registration code is IRCT20240808062692N1.

背景:痔疮切除术后疼痛仍然是影响患者术后恢复和满意度的一个常见和令人痛苦的因素。先发制人镇痛是术前预防中枢致敏,减少术后早期疼痛的一种治疗措施。目的:探讨静脉注射酮罗拉酸对痔疮切除术后患者疼痛程度的影响。方法:在这项随机临床试验中,61名计划进行痔疮切除术的成年人被分配到诱导前静脉注射30mg酮罗拉酸(干预组)或不预先镇痛(对照组)。两组术后均按需给予哌替啶治疗突破性疼痛。术后1和4小时采用口头评定量表(VRS)评估疼痛严重程度,并记录术后阿片类药物用量。结果:61例患者中,干预组32例,对照组29例。两组患者年龄、性别差异无统计学意义(p < 0.05)。结果显示,干预组术后1小时和4小时疼痛严重程度明显降低(p)。结论:我们发现非甾体抗炎药,特别是酮罗拉酸,可以作为先发制人的药物来减轻术后疼痛,减少阿片类药物的使用。这可能会减少阿片类药物的副作用。但是,必须对更大的人口和更长的随访期进行进一步评价。该随机临床试验注册代码为IRCT20240808062692N1。
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引用次数: 0
Do hospital and surgeon volumes impact the outcomes of patients undergoing cholecystectomy in Ireland? A national registry based study. 医院和外科医生的数量会影响爱尔兰胆囊切除术患者的预后吗?一项基于国家登记的研究。
IF 2.3 4区 医学 Q2 SURGERY Pub Date : 2025-12-01 DOI: 10.1016/j.surge.2025.08.008
E Linehan, J D Kehoe, T Gall, G McEntee, J Conneely, R M O'Connell

Introduction: Biliary pathology can have an enormous burden on both the patient and the health service with acute cholecystitis being diagnosed in 10 % of patients that present with acute abdominal pain. Emergency or elective laparoscopic cholecystectomy is the recommended treatment option for these patients. It has been shown previously that surgical and hospital volume affect outcomes from emergency abdominal surgery in Ireland, but no such investigation has been done specifically for cholecystectomies.

Aim: To determine if there is a link between the hospital and surgeon volume of cholecystectomies performed and their associated outcomes in Irish hospitals.

Methods: This was a retrospective registry study using National Quality Assurance & Improvement System (NQAIS). All patients who underwent cholecystectomy in Irish public hospitals from January 2017 until December 2023 were identified. Hospitals and surgeons were divided into groups of high, medium and low volume based on the number of cholecystectomies performed per year during the study period. Data including the demographics, admission details and outcomes of patients who underwent cholecystectomy were extracted from the database for analysis.

Results: A total of 28,835 patients in 35 hospitals were included. Adverse outcomes were reported in 1952 patients who underwent a cholecystectomy. An association was found between adverse outcomes including bile duct injury (0.10 % vs 0.03 %, p < 0.001) and critical care admission (2.7 % vs 1.97 %, p < 0.022) and patients who had surgery in low volume hospitals compared to high volume centres. No statistically significant difference in adverse outcome was reported for the low surgical volume patients. Risk factors associated with adverse outcome following cholecystectomy were age >65, high pre-operative morbidity, emergency surgery and low hospital volume (p < 0.001).

Discussion: Patients undergoing cholecystectomy in low volume hospitals have a higher risk of adverse events. Surgeons who perform low volumes of cholecystectomies appear to perform a higher percentage of emergency cholecystectomies without a statistically significant difference in their outcomes.

导言:10%的急性腹痛患者被诊断为急性胆囊炎,胆道病理对患者和卫生服务都是巨大的负担。紧急或选择性腹腔镜胆囊切除术是这些患者的推荐治疗选择。以前有研究表明,在爱尔兰,外科手术和医院的数量会影响急诊腹部手术的结果,但没有专门针对胆囊切除术进行过这样的调查。目的:确定爱尔兰医院胆囊切除术的医院和外科医生数量及其相关结果之间是否存在联系。方法:采用国家质量保证与改进系统(NQAIS)进行回顾性登记研究。从2017年1月到2023年12月,所有在爱尔兰公立医院接受胆囊切除术的患者都被确定。根据研究期间每年进行的胆囊切除术数量,将医院和外科医生分为高、中、低容量组。从数据库中提取胆囊切除术患者的人口统计学、入院细节和结局等数据进行分析。结果:共纳入35家医院28835例患者。报告了1952例胆囊切除术患者的不良结果。发现不良结局包括胆管损伤(0.10% vs 0.03%, p 65)、术前高发病率、急诊手术和低医院容量(p讨论:在小容量医院接受胆囊切除术的患者有更高的不良事件风险。施行小容量胆囊切除术的外科医生施行急诊胆囊切除术的比例似乎更高,但其结果没有统计学上的显著差异。
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引用次数: 0
Mentorship may benefit medical student learning in theatre as well as career aspirations in surgery. 师徒关系可能有利于医学生在戏剧领域的学习以及在外科领域的职业抱负。
IF 2.3 4区 医学 Q2 SURGERY Pub Date : 2025-11-22 DOI: 10.1016/j.surge.2025.11.007
Joseph E McKay, Lachlan Dick
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引用次数: 0
Facial injuries in major trauma patients in Ireland. 爱尔兰重大创伤患者的面部损伤。
IF 2.3 4区 医学 Q2 SURGERY Pub Date : 2025-11-20 DOI: 10.1016/j.surge.2025.11.006
David M McGoldrick, Rachel O'Donoghue, Olga Brych, Pamela Hickey, Conor M Bowe

Introduction: Major trauma is associated with significant morbidity and mortality. Facial injuries are often present in those sustaining major trauma. We sought to examine the Irish trauma registry to further assess this association.

Materials and methods: A retrospective analysis of the Irish trauma registry, the Major Trauma Audit, from 2017 to 2022 was performed. Patients over 16 years who had sustained major trauma were included in the analysis. The presence of an associated facial injury was further analysed.

Results: A total of 8943 patients were included in the analysis. A facial injury was seen in 18.9 % of patients. The majority of those sustaining a concurrent facial injury were male (69 %) and the median age was 59 years. Falls <2m (42.9 %) and road traffic collisions (27.6 %) were the commonest mechanisms of injury. A significant head injury was more commonly seen in those who also sustained facial trauma (84.9 % vs 58 %).

Conclusion: Facial injuries are commonly seen in patients who sustain major trauma. They may also indicate the presence of a concurrent head injury.

简介:重大创伤与显著的发病率和死亡率相关。面部损伤经常出现在那些遭受重大创伤的人身上。我们试图检查爱尔兰创伤登记处,以进一步评估这种关联。材料和方法:对2017年至2022年爱尔兰创伤登记处(主要创伤审计)进行回顾性分析。16岁以上遭受重大创伤的患者被纳入分析。进一步分析是否存在相关的面部损伤。结果:共纳入8943例患者。18.9%的患者出现面部损伤。大多数并发面部损伤的患者为男性(69%),中位年龄为59岁。结论:面部损伤常见于遭受重大创伤的患者。它们也可能表明同时存在头部损伤。
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引用次数: 0
Strengthening the innovation ecosystem to address global surgical needs - A consensus statement from the Innovations in Global Surgery (IGS) consortium. 加强创新生态系统以满足全球手术需求——全球外科创新(IGS)联盟的共识声明。
IF 2.3 4区 医学 Q2 SURGERY Pub Date : 2025-11-19 DOI: 10.1016/j.surge.2025.10.010
Deepa Kizhakke Veetil, Priyansh Nathani, Vijna Boodhoo, Anurag Mishra, Noel Aruparayil, Lovenish Bains

Background: The Lancet Commission on Global Surgery (LCoGS) highlighted a critical gap in global health by emphasising the lack of access to safe surgery in low- and middle-income countries (LMICs). With five billion people unable to access safe and affordable surgical care, the commission called for innovations tailored to local needs rather than high-income solutions. The Karad Consensus further emphasised the need for context-specific solutions for India's rural populations, advocating for innovative approaches to tackle surgical disparities. Inspired by these calls, the Innovations in Global Surgery (IGS) group was formed, aiming to foster a multidisciplinary and collaborative ecosystem to address surgical access challenges in LMICs.

Methods: This consensus statement, derived from three international conferences, explores key challenges and offers actionable solutions in areas such as context-specific surgical needs, training, communication between medical and engineering professionals, funding, credibility building, and regulatory processes.

Results: The IGS group emphasises the importance of inclusive and frugal innovations that involve end-users and respond to the unique challenges of resource-limited settings. It aims to bridge the gap between disciplines and regions, ensuring that new technologies and practices can be effectively adapted and scaled to meet the needs of underserved populations. The proposed action items will be tested and refined over the coming years to enhance global surgical care and improve health equity.

Conclusion: This consensus statement serves as a roadmap for driving sustainable, context-aware innovations in global surgery, leveraging the expertise of multidisciplinary stakeholders and creating a platform for continuous collaboration and knowledge sharing.

背景:《柳叶刀》全球外科委员会(LCoGS)通过强调低收入和中等收入国家(LMICs)缺乏获得安全手术的机会,强调了全球卫生方面的一个重大差距。由于50亿人无法获得安全和负担得起的外科护理,该委员会呼吁根据当地需求进行创新,而不是采用高收入解决方案。Karad共识进一步强调了为印度农村人口制定因地制宜的解决方案的必要性,倡导采用创新方法来解决手术差异问题。受这些呼吁的启发,成立了全球外科创新(IGS)小组,旨在建立一个多学科协作生态系统,以解决中低收入国家的手术准入挑战。方法:该共识声明源自三个国际会议,探讨了具体手术需求、培训、医学和工程专业人员之间的沟通、资金、信誉建立和监管流程等领域的关键挑战并提供了可行的解决方案。结果:IGS小组强调了包括最终用户在内的包容性和节约型创新的重要性,并应对资源有限环境下的独特挑战。它旨在弥合学科和地区之间的差距,确保新技术和实践能够有效地适应和扩大规模,以满足服务不足人口的需求。拟议的行动项目将在今后几年中得到检验和完善,以加强全球外科护理和改善卫生公平。结论:本共识声明可作为推动全球外科可持续、情境感知创新的路线图,利用多学科利益相关者的专业知识,创建持续协作和知识共享的平台。
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引用次数: 0
List of editors 编辑人员名单
IF 2.3 4区 医学 Q2 SURGERY Pub Date : 2025-11-18 DOI: 10.1016/S1479-666X(25)00163-5
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引用次数: 0
Low-cost and bendable patient-specific three-dimensional pulmonary vessel models for lung segmentectomy. 用于肺段切除术的低成本和可弯曲的患者特异性三维肺血管模型。
IF 2.3 4区 医学 Q2 SURGERY Pub Date : 2025-11-14 DOI: 10.1016/j.surge.2025.11.005
Toshihiro Ojima, Tomoshi Tsuchiya, Naru Kitade, Ryo Yokoyama, Naoya Kitamura, Koichiro Shimoyama

Background: Lung segmentectomy offers the advantages of preserving pulmonary function and improving patient survival, leading to its increased adoption. However, this procedure is technically demanding, especially when compared with lobectomy, owing to anatomical shifts from intraoperative lung collapse and manipulation. To support thoracic surgeons and enhance their surgical training, we developed a low-cost, patient-specific, and bendable three-dimensional (3D) pulmonary vessel model. This study describes the development, clinical application, and evaluation of this model.

Methods: A flexible 3D pulmonary vessel model was created using thermoplastic polyurethane (TPU) filaments. Preoperative thin-slice computed tomography images were processed using SYNAPSE VINCENT® (FUJIFILM, Japan) to annotate the pulmonary arteries, veins, bronchi, and tumors. Data were converted into stereolithography format using OsiriXMD (Pixmeo SARL, Switzerland) and printed using Adventure 5M Pro (FLASHFORGE JAPAN, Japan). These models were used for surgical planning, intraoperative navigation, and resident education.

Results: Between September 2024 and January 2025, 31 lung segmentectomies were performed with reference to TPU-based models. Cost of the TPU filament was approximately $1 per vessel, totaling approximately $2 per patient, and printing time was approximately 3 h per model. Compared with polylactic acid models, TPU models demonstrated superior flexibility in simulating vascular deformation caused by lung traction. Their use has improved anatomical understanding, facilitated intraoperative vessel recognition, and proved valuable in surgical training.

Conclusion: Bendable TPU-based 3D pulmonary vessel models are cost-effective and anatomically accurate tools with broad potential for use in thoracic surgery, particularly in planning, navigation, and education.

背景:肺段切除术具有保留肺功能和提高患者生存率的优点,因此被越来越多地采用。然而,由于术中肺塌陷和操作的解剖变化,该手术在技术上要求很高,特别是与肺叶切除术相比。为了支持胸外科医生并加强他们的手术训练,我们开发了一种低成本的、针对患者的、可弯曲的三维肺血管模型。本研究描述了该模型的发展、临床应用和评价。方法:采用热塑性聚氨酯(TPU)长丝制作柔性三维肺血管模型。术前使用SYNAPSE VINCENT®(FUJIFILM, Japan)处理薄层计算机断层扫描图像,对肺动脉、静脉、支气管和肿瘤进行注释。使用OsiriXMD (Pixmeo SARL,瑞士)将数据转换成立体光刻格式,并使用Adventure 5M Pro (FLASHFORGE JAPAN,日本)进行打印。这些模型用于手术计划、术中导航和住院医师教育。结果:2024年9月至2025年1月,参照tpu模型行肺段切除术31例。TPU灯丝的成本约为每个血管1美元,每位患者总计约2美元,每个模型的打印时间约为3小时。与聚乳酸模型相比,TPU模型在模拟肺牵引引起的血管变形方面表现出更强的灵活性。它们的使用提高了对解剖学的理解,促进了术中血管的识别,并在外科训练中证明了其价值。结论:基于可弯曲tpu的三维肺血管模型是一种具有成本效益和解剖精度的工具,在胸外科手术中具有广泛的应用潜力,特别是在计划、导航和教育方面。
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引用次数: 0
Determinants of burnout and satisfaction among urology trainees in the UK: A thematic analysis and critical evaluation of available data. 倦怠和满意度的决定因素在泌尿外科学员在英国:一个专题分析和现有数据的关键评价。
IF 2.3 4区 医学 Q2 SURGERY Pub Date : 2025-11-12 DOI: 10.1016/j.surge.2025.11.003
Dayan Jacob, Nidhi Manoj, Mehwash Nadeem

Background: Burnout among surgical trainees is a growing concern, with UK urology trainees facing unique stressors including increasing service demands, prolonged training, and limited specialty-specific data. This narrative review synthesizes current evidence on burnout and satisfaction among UK urology trainees and evaluates available interventions and contrast it to international cohorts.

Methods: A systematic search was conducted following PRISMA guidelines across six databases. Studies published over the last 25 years addressing burnout in UK urology trainees were identified, screened, and analyzed thematically.

Results: Four studies met inclusion criteria, underscoring the scarcity of targeted research. Burnout prevalence among UK urology trainees ranged from 28.4 % to 56 %. Key contributing factors included rota gaps, excessive workloads, limited protected training time, financial strain, and toxic organizational culture. Despite these challenges, 69 % of trainees reported they would choose the specialty again, highlighting the mitigating role of job satisfaction drivers such as operative experience, team camaraderie, and patient impact. Intervention-wise, the Reboot-C coaching program demonstrated a 12 % reduction in burnout scores and improved resilience, although its scalability and long-term effects remain uncertain. Broader cultural and structural interventions, such as mentorship programs, flexible training pathways, and resilience training, show promise but require further evaluation.

Conclusion: Burnout among UK urology trainees is a significant and multifactorial issue. While isolated interventions show benefit, systemic reform is essential. Future research should adopt longitudinal, intersectional approaches to inform evidence-based policy and workforce planning.

背景:外科受训者的职业倦怠越来越受到关注,英国泌尿外科受训者面临着独特的压力源,包括不断增加的服务需求、延长的培训和有限的专业数据。本综述综合了英国泌尿外科受训者的职业倦怠和满意度的现有证据,评估了可用的干预措施,并将其与国际队列进行了对比。方法:在6个数据库中按照PRISMA指南进行系统检索。在过去的25年里发表的关于英国泌尿外科实习生倦怠的研究被确定、筛选和分析。结果:4项研究符合纳入标准,强调了针对性研究的稀缺性。英国泌尿外科受训人员的倦怠率从28.4%到56%不等。关键的影响因素包括轮班空缺、过度的工作量、有限的受保护培训时间、财务压力和有害的组织文化。尽管面临这些挑战,69%的学员表示他们会再次选择该专业,这突出了工作满意度驱动因素的缓解作用,如手术经验、团队友情和对患者的影响。干预方面,Reboot-C培训项目显示倦怠得分降低了12%,并提高了恢复力,尽管其可扩展性和长期效果仍不确定。更广泛的文化和结构干预,如指导计划、灵活的培训途径和弹性培训,显示出希望,但需要进一步评估。结论:英国泌尿外科实习生的职业倦怠是一个重要的多因素问题。虽然孤立的干预会带来好处,但系统性改革至关重要。未来的研究应采用纵向、交叉的方法,为循证政策和劳动力规划提供信息。
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引用次数: 0
The role for dedicated Periprosthetic Joint Infection (PJI) specialist centres in Ireland. 爱尔兰专门的假体周围关节感染(PJI)专家中心的作用。
IF 2.3 4区 医学 Q2 SURGERY Pub Date : 2025-11-10 DOI: 10.1016/j.surge.2025.09.009
Patrick Nolan, Concepta Merry, Susie Clarke, Tom McCarthy, Joseph Queally, Andrew J Hughes
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引用次数: 0
Target outflow vessel compromise after failed endovascular interventions for infra-inguinal arterial disease. 腹股沟下动脉疾病的血管内干预失败后靶流出血管受损。
IF 2.3 4区 医学 Q2 SURGERY Pub Date : 2025-11-09 DOI: 10.1016/j.surge.2025.11.002
Mohammed Elkassaby, Surbhi Chawla, Mary-Paula Colgan, Caitriona Canning, Adrian O'Callaghan, Zenia Martin, Sean O'Neill, Prakash Madhavan

Introduction: Even after two major RCTs, the BEST CLI and BASIL II, the debate about best strategy to address infra-inguinal arterial disease continues. Damage of distal outflow vessels after failed angioplasties and compromise to future options remains the main concern of bypass-first strategy advocates versus endovascular enthusiasts.

Objectives: To assess the degree of target outflow vessels damage after failed angioplasties.

Methods: This was a retrospective study looking at all episodes of failed angioplasties for infra-inguinal arterial disease over 5 years. Primary end points were the presence and extent of damage to target outflow vessels. Secondary endpoints included complications, mortality, re-intervention types, and their success rates.

Results: There were 101 failed episodes out of 724 infra-inguinal angioplasties (primary success 86 %). The mean age of failed angioplasty cases was 73 (+- 10.5) years. There was no damage to target outflow vessels after failed angioplasty in 78.2 % of the episodes. Redo angioplasty was attempted in 43 %, with 42 % success rate (p-value 0.069), while Open surgical bypass "OSB" was performed for 21 % of the cases with a success rate of 91 % (p-value 0.009) CONCLUSION: An endovascular-first strategy for treatment of peripheral arterial disease "PAD is safe and effective. The concern for compromised future options is not justified.

即使在两项主要的随机对照试验(BEST CLI和BASIL II)之后,关于治疗腹股沟下动脉疾病的最佳策略的争论仍在继续。血管成形术失败后远端流出血管的损伤和对未来选择的妥协仍然是旁路优先策略的支持者和血管内支持者的主要关注点。目的:评价血管成形术失败后靶流出血管的损伤程度。方法:这是一项回顾性研究,研究了5年来所有腹股沟下动脉疾病血管成形术失败的病例。主要终点是目标流出血管损伤的存在和程度。次要终点包括并发症、死亡率、再干预类型及其成功率。结果:724例腹股沟下血管成形术中有101例失败(初次成功率86%)。血管成形术失败患者的平均年龄为73岁(±10.5岁)。78.2%的血管成形术失败后靶流出血管无损伤。43%的患者尝试再次行血管成形术,成功率为42% (p值0.069),21%的患者行开放手术旁路“OSB”,成功率为91% (p值0.009)。结论:血管内优先治疗外周动脉疾病“PAD”安全有效。担心未来的选择会受到损害是没有道理的。
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引用次数: 0
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Surgeon-Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
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