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Comparative study of the outcomes of one-stage versus two-stage reconstruction of chronic multiligament knee injury. 慢性膝关节多韧带损伤一期重建与二期重建疗效比较研究。
IF 2.3 4区 医学 Q2 SURGERY Pub Date : 2024-10-27 DOI: 10.1016/j.surge.2024.10.004
S A Arojuraye, Ibrahim Abolaji Alabi, Ndubuisi Okoh, Folajuwon Bayode Ayeni, Musliu Kolawole Odunola, M N Salihu

Background: Multi-ligament knee injury (MLKI) is a complex orthopaedic knee problem, usually following traumatic knee dislocation. Surgical management is preferred and has resulted in better clinical outcomes. However, the optimal surgical treatment protocol is continuously evolving. This study aimed to compare the outcomes of one-stage versus two-stage reconstruction of MLKI.

Materials and methods: This retrospective comparative study was conducted between July 2020 and December 2023 at a government orthopaedic hospital in Nigeria. The inclusion criteria include males and females between 18 and 45 years of age who had one- or two staged knee reconstructions for MLKI and were followed up for a minimum of 12 months. The exclusion criteria were patients below 18 and above 45 years of age, those with previous knee surgery, those associated with femoral or tibia fractures, those with radiological evidence of osteoarthritis, and those with follow-ups less than 12 months. Clinical outcomes using the Lysholm scoring system and complication rate were recorded. The statistical analysis was performed using SPSS version 23.

Results: Fifty-one patients (26 in the OS group and 25 in the TS group) were studied. There was a significant difference between the preoperative and postoperative Lysholm scores in the two groups (p = 0.86 and 0.57 for OS and TS, respectively). However, there was no significant difference between the postoperative Lysholm scores in the two groups (p = 0.918).

Conclusion: One-stage and two-stage reconstruction of chronic MLKI give similar excellent clinical outcomes.

背景:多韧带膝关节损伤(MLKI)是一种复杂的膝关节矫形问题,通常发生在外伤性膝关节脱位之后。手术治疗是首选,并能带来更好的临床疗效。然而,最佳手术治疗方案仍在不断演变。本研究旨在比较一期与二期重建 MLKI 的疗效:这项回顾性比较研究于 2020 年 7 月至 2023 年 12 月在尼日利亚一家政府骨科医院进行。纳入标准包括年龄在 18 至 45 岁之间、接受过一期或二期膝关节重建术的 MLKI 男性和女性患者,并进行了至少 12 个月的随访。排除标准包括年龄在 18 岁以下和 45 岁以上的患者、曾接受过膝关节手术的患者、股骨或胫骨骨折患者、有骨关节炎放射学证据的患者以及随访时间少于 12 个月的患者。采用 Lysholm 评分系统记录临床结果和并发症发生率。统计分析采用 SPSS 23 版本:研究了 51 例患者(OS 组 26 例,TS 组 25 例)。两组患者术前和术后的 Lysholm 评分有明显差异(OS 组和 TS 组的 P = 0.86 和 0.57)。然而,两组患者术后的 Lysholm 评分无明显差异(P = 0.918):结论:慢性 MLKI 的一期重建和二期重建具有相似的良好临床效果。
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引用次数: 0
Thirty-day outcomes of Asian Americans in endovascular repair of intact infrarenal abdominal aortic aneurysm. 亚裔美国人接受完整的肾下腹主动脉瘤血管内修复术后三十天的疗效。
IF 2.3 4区 医学 Q2 SURGERY Pub Date : 2024-10-27 DOI: 10.1016/j.surge.2024.10.005
Renxi Li, Anton Sidawy, Bao-Ngoc Nguyen

Background: Endovascular aneurysm repair (EVAR) has become the predominant treatment for Abdominal aortic aneurysm (AAA). Racial disparity has been observed in EVAR but Asian Americans have been largely excluded from previous studies. This study aimed to comprehensively evaluate 30-day outcomes of Asian Americans undergoing EVAR for intact infrarenal AAA using a multi-institutional national database.

Methods: Patients who underwent infrarenal EVAR from 2012 to 2022 were identified in the ACS-NSQIP database. Exclusion criteria included age less than 18 years, emergency presentation, and acute intraoperative conversion to open. A 1:3 propensity-score matching was applied to Asian Americans and Caucasians to match their demographics, comorbidities, aneurysm diameter, distant extent of the aneurysm, anesthesia, and concomitant procedures. Thirty-day postoperative outcomes were examined.

Results: Among 16,463 patients who underwent EVAR for non-ruptured infrarenal AAA, 302 (1.83 %) were Asian Americans and 12,373 (75.16 %) were Caucasians. Asian Americans had older age and higher burdens of medical comorbidities. After propensity-score matching, Asian American and Caucasian patients had comparable 30-day outcomes including mortality (1.99 % vs 1.34 %, p = 0.42), cardiac complications (2.32 % vs 1.56 %, p = 0.45), pulmonary complications (2.32 % vs 1.89 %, p = 0.64), and renal complications (1.99 % vs 0.89 %, p = 0.13). However, Asian American patients had a longer operative time (155.80 ± 84.59 vs 136.60 ± 69.60 min, p < 0.01) and length of stay (3.60 ± 6.16 vs 2.71 ± 4.50 days, p = 0.01). All other 30-day outcomes were comparable between Asian American and Caucasian patients.

Conclusion: Asian Americans might be underrepresented in EVAR due to limited healthcare access or a more insidious disease progression. After propensity-score matching, Asian Americans showed similar 30-day outcomes as their Caucasian counterparts. Thus, when given access, EVAR can be as effective and safe for Asian American patients. Future research should investigate the long-term prognosis for Asian Americans after EVAR.

背景:血管内动脉瘤修补术(EVAR)已成为治疗腹主动脉瘤(AAA)的主要方法。在 EVAR 中已观察到种族差异,但亚裔美国人在以前的研究中基本上被排除在外。本研究旨在利用多机构国家数据库,全面评估亚裔美国人因完整的肾下动脉瘤接受EVAR手术的30天结果:方法:从 ACS-NSQIP 数据库中筛选出 2012 年至 2022 年期间接受肾下动脉 AAA EVAR 手术的患者。排除标准包括年龄小于18岁、急诊就诊和术中急性转为开放手术。对亚裔美国人和白种人进行了1:3倾向得分匹配,以匹配他们的人口统计学特征、合并症、动脉瘤直径、动脉瘤远端范围、麻醉和伴随手术。结果:在16,463名因肾下动脉瘤未破裂而接受EVAR手术的患者中,302人(1.83%)为亚裔美国人,12,373人(75.16%)为白种人。亚裔美国人年龄较大,合并症较多。经过倾向分数匹配后,亚裔美国人和白种人患者的 30 天结果相当,包括死亡率(1.99 % vs 1.34 %,p = 0.42)、心脏并发症(2.32 % vs 1.56 %,p = 0.45)、肺部并发症(2.32 % vs 1.89 %,p = 0.64)和肾脏并发症(1.99 % vs 0.89 %,p = 0.13)。然而,亚裔美国人患者的手术时间更长(155.80 ± 84.59 vs 136.60 ± 69.60 分钟,p 结论:亚裔美国人患者的手术时间更长:亚裔美国人接受EVAR手术的人数可能不足,原因可能是医疗服务有限或疾病进展更隐匿。经过倾向分数匹配后,亚裔美国人的 30 天结果与白种人相似。因此,只要有机会,EVAR 对亚裔美国人患者同样有效和安全。未来的研究应调查亚裔美国人在EVAR术后的长期预后。
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引用次数: 0
Demographics of deceased organ donation in Ireland: A 10 year review showing the worrying increase of suicide as a source for organ donation. 爱尔兰已故器官捐赠的人口统计数据:10 年回顾:自杀作为器官捐献来源的增加令人担忧。
IF 2.3 4区 医学 Q2 SURGERY Pub Date : 2024-10-26 DOI: 10.1016/j.surge.2024.10.003
S G Potts, Ellen Small, Ian Currie
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引用次数: 0
Patient-reported outcomes in Irish adolescents who were born with cleft lip and palate. 爱尔兰先天性唇腭裂青少年的患者报告结果。
IF 2.3 4区 医学 Q2 SURGERY Pub Date : 2024-10-16 DOI: 10.1016/j.surge.2024.10.002
K Nolan, Y MacAuley, S Byrne, C de Blacam

Background & purpose: Cleft Lip and/or Palate, which affects approximately 1:650 live births in Ireland, is a complex congenital condition with lifelong implications. It can affect upper airway function, feeding, hearing, speech development, dental development as well as oral functioning, facial growth and physical appearance. Within cleft surgery, rigorous audit of speech, facial growth and nasolabial aesthetic outcomes is well-established. The importance of including patient-reported outcomes in our routine data-collection is now recognised. The purpose of the current study was to examine patient-reported outcomes (PROs) in a consecutive series of adolescents attending the Dublin Cleft Centre (DCC).

Methods: A validated patient-reported outcome measure (PROM), the CLEFT-Q, was prospectively administered to 156 patients attending the cleft clinic. Results were analysed according to cleft type and compared to those recorded in the CLEFT-Q validation study.

Results: Between (February 2020 and March 2022), the CLEFT-Q was administered to 156 patients with a mean age of 13.5 years (range 10-19 years). Males scored higher satisfaction across all subdomains irrespective of age. Satisfaction was higher in younger age groups compared to older patients in both appearance and quality of life outcomes. Patients with isolated cleft palate scored highest for satisfaction in school, social and psychological function.

Conclusions: PRO data now informs consultations with patients and families at the DCC. This information is also useful in targeting service development to the specific needs of this patient group.

背景与目的:在爱尔兰,唇裂和/或腭裂的发病率约为 1:650,是一种复杂的先天性疾病,会影响患者的一生。它会影响上气道功能、喂养、听力、语言发育、牙齿发育以及口腔功能、面部发育和外貌。在唇裂手术中,对言语、面部发育和鼻唇美学效果的严格审核是公认的。目前,我们已认识到在常规数据收集中纳入患者报告结果的重要性。本研究的目的是对连续接受都柏林裂隙中心(DCC)治疗的青少年进行患者报告结果(PROs)检查:方法:对到都柏林裂隙中心就诊的 156 名患者进行了前瞻性的患者报告结果测量 (PROM),即 CLEFT-Q。根据裂隙类型对结果进行分析,并与 CLEFT-Q 验证研究中记录的结果进行比较:在(2020 年 2 月至 2022 年 3 月)期间,对 156 名平均年龄为 13.5 岁(10-19 岁不等)的患者进行了 CLEFT-Q 测试。无论年龄大小,男性在所有子域的满意度均较高。与年龄较大的患者相比,年龄较小的患者在外观和生活质量方面的满意度都较高。孤立性腭裂患者在学校、社交和心理功能方面的满意度得分最高:目前,PRO 数据可为 DCC 与患者及家属的协商提供参考。这些信息也有助于针对这一患者群体的特殊需求进行服务开发。
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引用次数: 0
The role of gastropexy in paraesophageal hernia repair: A scoping review of current evidence. 胃镜在食道旁疝修补术中的作用:对当前证据的范围审查。
IF 2.3 4区 医学 Q2 SURGERY Pub Date : 2024-10-16 DOI: 10.1016/j.surge.2024.10.001
Haneen Kamran, Hamza Shafiq, Misha Mansoor, Umm-E-Aimen Minhas, Sameen Tahira, Sameen Shahid, Farah Khan

Background: Paraesophageal hernias (PEH), involving abdominal components herniating through the esophageal hiatus, pose serious risks like obstruction and perforation, prompting SAGES to recommend repair upon symptom onset in 2013. Despite surgical advancements, high recurrence rates persist post-PEH repair. Gastropexy, securing the stomach to prevent re-herniation, emerges as a potential solution. However, consensus on its application is lacking. This review aims to map existing research, summarize evidence, and identify gaps guiding future gastropexy research in PEH repair.

Methods: Following PRISMA guidelines, this scoping review conducted a comprehensive literature search using PubMed, Cochrane, and Embase. Eligible studies, including RCTs, observational, and cohort studies, described gastropexy for PEH treatment in adults published in English after 2013. Articles were rigorously screened, with data extracted and organized into tables detailing study characteristics, conditions, and outcomes.

Results: A search yielded 343 studies on gastropexy for PEH, with 17 meeting inclusion criteria. Most were retrospective (47.1 %) or case series (41.2 %). GP, primarily in types III and IV hernias, was mainly performed laparoscopically. Anterior GP was most commonly used (in 64.7 % of included studies), with some studies using additional techniques. Reduced recurrence rates were seen when adjunct procedures such as fundoplication were performed with gastropexy.

Conclusion: This review highlights the varied application of gastropexy in PEH repair, aiming to reconcile differing surgeon opinions. The data suggests gastropexy can be safely utilised across different techniques, offering a viable option for addressing PEH and reducing hernia recurrence, particularly in high-risk cases.

背景:食管旁疝(PEH)是指腹腔成分通过食管裂孔疝出,具有梗阻和穿孔等严重风险,这促使 SAGES 在 2013 年建议在症状出现时进行修复。尽管手术技术不断进步,但食管裂孔修补术后的复发率仍然很高。胃切除术是一种潜在的解决方案,可固定胃部以防止再次疝出。然而,人们对其应用还缺乏共识。本综述旨在绘制现有研究图谱、总结证据并找出差距,以指导未来在 PEH 修复术中进行胃穿孔术的研究:本范围界定综述遵循 PRISMA 指南,使用 PubMed、Cochrane 和 Embase 进行了全面的文献检索。符合条件的研究包括 RCT、观察性研究和队列研究,均为 2013 年后发表的英文文章,描述了成人 PEH 治疗中的胃镜手术。文章经过严格筛选,提取数据并整理成表格,详细列出了研究特点、条件和结果:检索结果显示,共有 343 篇关于胃镜手术治疗 PEH 的研究,其中 17 篇符合纳入标准。大部分为回顾性研究(47.1%)或病例系列研究(41.2%)。GP主要用于III型和IV型疝气,以腹腔镜手术为主。最常用的是前路 GP(占纳入研究的 64.7%),有些研究还使用了其他技术。在胃镜下进行胃底折叠术等辅助手术可降低复发率:本综述强调了胃螺钉术在 PEH 修复中的不同应用,旨在调和外科医生的不同观点。数据表明,胃切除术可以安全地应用于不同的技术,为解决 PEH 和减少疝气复发提供了一个可行的选择,尤其是在高风险病例中。
{"title":"The role of gastropexy in paraesophageal hernia repair: A scoping review of current evidence.","authors":"Haneen Kamran, Hamza Shafiq, Misha Mansoor, Umm-E-Aimen Minhas, Sameen Tahira, Sameen Shahid, Farah Khan","doi":"10.1016/j.surge.2024.10.001","DOIUrl":"https://doi.org/10.1016/j.surge.2024.10.001","url":null,"abstract":"<p><strong>Background: </strong>Paraesophageal hernias (PEH), involving abdominal components herniating through the esophageal hiatus, pose serious risks like obstruction and perforation, prompting SAGES to recommend repair upon symptom onset in 2013. Despite surgical advancements, high recurrence rates persist post-PEH repair. Gastropexy, securing the stomach to prevent re-herniation, emerges as a potential solution. However, consensus on its application is lacking. This review aims to map existing research, summarize evidence, and identify gaps guiding future gastropexy research in PEH repair.</p><p><strong>Methods: </strong>Following PRISMA guidelines, this scoping review conducted a comprehensive literature search using PubMed, Cochrane, and Embase. Eligible studies, including RCTs, observational, and cohort studies, described gastropexy for PEH treatment in adults published in English after 2013. Articles were rigorously screened, with data extracted and organized into tables detailing study characteristics, conditions, and outcomes.</p><p><strong>Results: </strong>A search yielded 343 studies on gastropexy for PEH, with 17 meeting inclusion criteria. Most were retrospective (47.1 %) or case series (41.2 %). GP, primarily in types III and IV hernias, was mainly performed laparoscopically. Anterior GP was most commonly used (in 64.7 % of included studies), with some studies using additional techniques. Reduced recurrence rates were seen when adjunct procedures such as fundoplication were performed with gastropexy.</p><p><strong>Conclusion: </strong>This review highlights the varied application of gastropexy in PEH repair, aiming to reconcile differing surgeon opinions. The data suggests gastropexy can be safely utilised across different techniques, offering a viable option for addressing PEH and reducing hernia recurrence, particularly in high-risk cases.</p>","PeriodicalId":49463,"journal":{"name":"Surgeon-Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142479006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transcatheter arterial embolisation (TAE) to treat acute upper gastrointestinal bleeding secondary to gastric cancer: A systematic review and meta-analysis. 经导管动脉栓塞(TAE)治疗继发于胃癌的急性上消化道出血:系统回顾和荟萃分析。
IF 2.3 4区 医学 Q2 SURGERY Pub Date : 2024-10-15 DOI: 10.1016/j.surge.2024.09.009
Tamzin Hall, Hugo C Temperley, Benjamin M Mac Curtain, Niall J O'Sullivan, Ned Quirke, Niall McEniff, Ian Brennan, Kevin Sheahan, Noel E Donlon

Introduction: Acute upper gastrointestinal bleeding (UGIB) secondary to gastric cancer presents a significant clinical challenge due to its high morbidity and mortality rates. Transcatheter arterial embolisation (TAE) has emerged as a potential therapeutic option for managing this condition, especially in the context of failed endoscopic management. This systematic review aims to evaluate the efficacy and safety of TAE in treating acute upper gastrointestinal (GI) bleeding caused by gastric cancer.

Methods: A systematic search of medical databases, including PubMed, MEDLINE, and EMBASE, was conducted for studies published between 2000 and 2023. Included studies reported on the use of TAE for acute upper GI bleeding specifically due to gastric cancer, including retrospective analyses, case reports, and cohort studies. Demographics and clinical outcomes were reported.

Results: A total of 7 studies met the inclusion criteria, all being retrospective in nature. The overall technical success rate of TAE was 94.9 %. Overall clinical success rates were 72 % with a 95 % confidence interval (CI) of 66-79 %. Overall rebleeding rates were 11 % with a 95 % CI of 3-18 %. Major complications were reported in 2.4 % of patients, including ischemic complications and organ perforation. The overall 30-day mortality rate was 26.4 %, primarily due to underlying disease progression rather than procedural complications.

Conclusion: TAE is an effective and safe intervention for managing acute upper GI bleeding secondary to gastric cancer, with high success rates. TAE should be considered a viable treatment modality for this challenging condition, particularly for patients who are being considered for neoadjuvant therapy or indeed those not suitable candidates for curative surgical intervention.

导言:继发于胃癌的急性上消化道出血(UGIB)因其高发病率和高死亡率而成为一项重大的临床挑战。经导管动脉栓塞术(TAE)已成为治疗这种疾病的一种潜在疗法,尤其是在内镜治疗失败的情况下。本系统性综述旨在评估经导管动脉栓塞治疗胃癌引起的急性上消化道(GI)出血的有效性和安全性:方法:对医学数据库(包括 PubMed、MEDLINE 和 EMBASE)中 2000 年至 2023 年间发表的研究进行了系统检索。纳入的研究报告了胃癌急性上消化道出血TAE的使用情况,包括回顾性分析、病例报告和队列研究。结果:共有 7 项研究符合纳入标准,均为回顾性研究。TAE 的总体技术成功率为 94.9%。总体临床成功率为 72%,95% 置信区间 (CI) 为 66-79%。总体再出血率为 11%,95% 置信区间为 3-18%。据报告,2.4%的患者出现重大并发症,包括缺血性并发症和器官穿孔。30天的总死亡率为26.4%,主要是由于潜在的疾病进展而非手术并发症:结论:TAE是治疗胃癌继发急性上消化道出血的一种有效而安全的干预措施,成功率高。对于这种具有挑战性的疾病,TAE应被视为一种可行的治疗方式,尤其是对于考虑接受新辅助治疗的患者或不适合接受根治性手术治疗的患者。
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引用次数: 0
Utilising a modified accelerated Delphi process to develop a national multidisciplinary consensus on peri-operative optimisation of patients with obesity undergoing non-bariatric surgery. 利用改良的加速德尔菲流程,就接受非减肥手术的肥胖症患者的围手术期优化达成全国多学科共识。
IF 2.3 4区 医学 Q2 SURGERY Pub Date : 2024-10-11 DOI: 10.1016/j.surge.2024.09.005
C Cullinane, A Edwards-Murphy, C Kennedy, C Toale, M Al Azzawi, M Davey, N Donlon, S Croghan, J Elliott, C Fleming

Background: In the last three decades, the worldwide prevalence of obesity has increased by threefold. Using a modified Delphi consensus technique, the Irish Surgical Research Collaborative (ISRC) aimed to formulate consensus guidelines on the peri-operative optimisation of patients with obesity undergoing non-bariatric surgery.

Methods: Subgroups within the ISRC were established to formulate consensus statements using a nominal group technique (NGT) to address the three domains of pre-operative, intra-operative and post-operative care. Three Delphi rounds were circulated nationally to multidisciplinary members of the peri-operative team via electronic survey. Consensus was considered achieved for any statement with >80 % agreement. Data was analysed using Microsoft Excel (Microsoft Corp, Redmond, WA).

Results: Following three Delphi rounds, a total of 94 statements centred around optimising peri-operative care for patients with obesity undergoing non-bariatric surgery reached consensus. Pre-operatively, access to prehabilitation, use of pre-operative risk stratification tools and strategies to reduce obesity-related co-morbidities were all deemed important along with nomination of a hospital obesity lead. Intra-operatively, the prioritised domains were involvement of consultant anaesthetist and surgeon for safe and considered patient positioning, utilisation of minimally invasive surgical techniques, adherence to venous thromboembolism prophylaxis and surgical site infection prevention strategies as well as adoption of multimodal analgesia. Appropriate analgesia prescription, nutritional support, enhanced recovery after surgery and the role of physiotherapy were all deemed essential elements of post-operative care.

Conclusion: As a multidisciplinary peri-operative group, through Delphi consensus, we report agreed perioperative standards to optimise the perioperative care of patients with obesity undergoing non-bariatric surgery. This consensus can be utilised to standardise clinical practice and identify areas for quality improvement.

背景:在过去的三十年里,全球肥胖症的发病率增加了三倍。爱尔兰外科研究合作组织(ISRC)采用改良德尔菲共识技术,旨在为接受非减肥手术的肥胖症患者制定围手术期优化共识指南:方法:爱尔兰外科研究合作组织(ISRC)内部成立了若干小组,采用名义小组技术(NGT)制定共识声明,以解决术前、术中和术后护理这三个领域的问题。在全国范围内通过电子调查向围术期团队的多学科成员分发了三轮德尔菲调查问卷。凡是达成一致意见>80%的声明均被视为已达成共识。数据使用 Microsoft Excel(Microsoft Corp,Redmond,WA)进行分析:经过三轮德尔菲讨论,围绕优化非减肥手术肥胖症患者的围手术期护理,共有 94 项声明达成了共识。术前康复、术前风险分层工具的使用、减少肥胖相关并发症的策略以及医院肥胖问题负责人的提名都被认为非常重要。在术中,优先考虑的领域包括麻醉师顾问和外科医生的参与,以确保患者体位的安全和周全、微创手术技术的使用、静脉血栓栓塞预防和手术部位感染预防策略的坚持以及多模式镇痛的采用。适当的镇痛处方、营养支持、促进术后恢复以及物理治疗的作用都被认为是术后护理的基本要素:作为一个多学科围手术期小组,通过德尔菲共识,我们报告了一致同意的围手术期标准,以优化接受非减肥手术的肥胖症患者的围手术期护理。这一共识可用于规范临床实践和确定质量改进的领域。
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引用次数: 0
Thyroid cancer epidemiology in Ireland from 1994 to 2019 - Rising diagnoses without mortality benefit. 1994 年至 2019 年爱尔兰甲状腺癌流行病学--诊断率上升,但死亡率并无改善。
IF 2.3 4区 医学 Q2 SURGERY Pub Date : 2024-10-07 DOI: 10.1016/j.surge.2024.08.017
Gerard P Sexton, Thomas J Crotty, Susannah M Staunton, Marie Louise Healy, James Paul O'Neill, Conrad Timon, John B Kinsella, Paul Lennon, Conall Wr Fitzgerald

Background: The epidemiology and management of thyroid cancer has changed radically in the recent past, with rising international incidence of early-stage papillary thyroid cancer (PTC) in particular. In this paper, we review the epidemiology of thyroid cancer in Ireland.

Methods: A retrospective cohort study of National Cancer Registry of Ireland data, 1994-2019.

Results: Records from 4158 patients were analysed. 73 % (n = 3040) were female. The average age was 50.4 years. Patient sex did not change over time (p = 0.662), while age decreased significantly (p < 0.0001). The most common diagnoses were PTC (n = 2,905, 70 %) and follicular thyroid carcinoma (n = 549, 13 %). Incidence rose over threefold (1.8-6.2 cases/100000 person-years). The incidence of T1 PTC rose over twelvefold (0.169-2.1 cases/100000 person-years), while the incidence of stage III and IV disease did not change significantly. Five-year disease-specific survival (DSS) was 85 % and varied significantly by diagnosis - 97 % for PTC versus 5 % for anaplastic thyroid carcinoma. Survival did not change significantly over time. Male sex was a risk factor for more advanced disease (p < 0.0001) but did not independently predict overall survival except in PTC (HR 1.6, p = 0.03). The use of radioactive iodine declined markedly from 49 % to 12.5 %. RAI improved DSS for PTC patients aged over 55 years (p = 0.02) without a notable effect on survival for those under 55 years (p = 0.99).

Conclusion: The epidemiology and management of thyroid cancer in Ireland has changed dramatically in a manner reflective of international trends.

背景:近年来,甲状腺癌的流行病学和管理发生了根本性变化,尤其是早期甲状腺乳头状癌(PTC)的国际发病率不断上升。本文回顾了爱尔兰甲状腺癌的流行病学:对 1994-2019 年爱尔兰国家癌症登记处的数据进行回顾性队列研究:分析了 4158 名患者的记录。73%(n = 3040)为女性。平均年龄为 50.4 岁。随着时间的推移,患者性别没有发生变化(p = 0.662),而年龄却显著下降(p 结论:爱尔兰癌症的流行病学和治疗方法在不断变化:爱尔兰甲状腺癌的流行病学和管理发生了巨大变化,反映了国际趋势。
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引用次数: 0
Outcomes for centenarian patients admitted with orthopaedic trauma. 因骨科创伤入院的百岁老人的治疗效果。
IF 2.3 4区 医学 Q2 SURGERY Pub Date : 2024-10-04 DOI: 10.1016/j.surge.2024.09.010
Andrew P Dekker, Prateek A Saxena, Emma Westwood, Niharika Kalla, Nathan Sims, Paul Wilson, Neil Ashwood

Introduction: The United Kingdom (UK) and world's population is aging with patients living longer, often with many co-morbidities. It is expected that patients of extreme old age would have poor outcomes following trauma; however, this assumption is not clearly evidenced. This study aims to present the outcomes of patients aged 100 or older admitted to a single hospital trust following admission for orthopaedic trauma.

Method: A prospective cohort of patients aged 100 years and over admitted to the trauma and orthopaedic departments of two hospitals within the same trust between 2008 and 2022 was reviewed. Age was median 101 years (100-106 years). Outcome measures were length of stay, survival, complications and change in accommodation.

Results: 80 patients met the inclusion criteria (71female, 9 male). Mean age at discharge was 102.5 years with survival mean 4.2 years. 2 patients with peri-prosthetic fracture survived a further 5 years. Mean length of stay was 17 days. 57 patients returned to their original place of residence. 72 patients (90 %) survived the acute hospital admission.

Conclusion: Survival rates for patients aged over 100 years were high and most returned to the previous place of residence. This study supports the surgical management of trauma and helps inform patients and families expectations for mortality risk.

导言:英国和全世界的人口都在老龄化,病人的寿命越来越长,而且往往合并多种疾病。人们预计,高龄患者在创伤后的治疗效果会很差;但这一假设并没有明确的证据。本研究旨在介绍一家医院托管机构收治的 100 岁或 100 岁以上骨科创伤患者的治疗效果:方法:研究人员回顾了 2008 年至 2022 年期间在同一托管医院的两家医院的创伤和矫形部门住院的 100 岁及以上患者的前瞻性队列。年龄中位数为 101 岁(100-106 岁)。结果包括住院时间、存活率、并发症和住宿条件变化:80名患者符合纳入标准(71名女性,9名男性)。出院时平均年龄为 102.5 岁,平均存活时间为 4.2 年。2名假体周围骨折的患者又存活了5年。平均住院时间为 17 天。57 名患者返回了原居住地。72名患者(90%)在急性住院期间存活下来:结论:100 岁以上患者的存活率很高,大多数患者都回到了原来的居住地。这项研究为创伤的外科治疗提供了支持,并有助于告知患者和家属对死亡风险的预期。
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引用次数: 0
A Letter to the editor: Parastomal hernia repairs: A nationwide cohort study in the Republic of Ireland. 致编辑的一封信:腹股沟旁疝修补术:爱尔兰共和国全国范围内的队列研究。
IF 2.3 4区 医学 Q2 SURGERY Pub Date : 2024-10-03 DOI: 10.1016/j.surge.2024.09.007
Amir Farah
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引用次数: 0
期刊
Surgeon-Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
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