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Liposarcoma suprarrenal derecho 右肾上腺脂肪肉瘤
Q4 Medicine Pub Date : 2018-09-20 DOI: 10.4067/s0718-40262018000500400
Nicolás Tarigo-Casella, Martín Vallverdú-Scorza, Daniel Yianssen, Roberto Valiñas-Sotelo
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引用次数: 0
Upper Body Lift: Serie de casos en un hospital clínico universitario entre los años 2013-2016. Descripción de la técnica quirúrgica 上身提升:2013-2016年某大学临床医院的一系列病例。手术技术描述
Q4 Medicine Pub Date : 2018-09-20 DOI: 10.4067/S0718-40262018000500402
E. S. Danilla, Carlos Domínguez, V. Ganz, O. E. Troncoso, V. Ríos, T. Yamada, D. Serra, C. Andrades, V. Cisternas, Cristián Erazo, P. Sepúlveda
Introduction: Obese patients gets beneficial health effects with the massive weight loss, however they develop excessive redundant skin and become physical problems affecting their quality of life. In severe cases, the conventional body contouring techniques are not able to solve this large alterations, being necessary to use more extensive procedures. The Upper Body Lift is a technique that offers integral management of the upper trunk. Objectives: To describe a case series of patients submitted to Upper Body Lift and present the surgical technique. Materials and Methods: Prospective case series of patients with Upper Body Lift between January 2013 and June 2016 in a clinical hospital. Patients with incomplete information or operated in another center were excluded. Descriptive statistics was used. Results: 8 patients were included, age 39.75 ± 9.37 years, 6 (75%) women. Prior to the contouring surgery they lose 36.75 ± 9.11 kg, reaching a BMI of 25.97 ± 2.35 kg/m2. In men the chest region was managed with liposuction and subsequent nipple graft, in women mastopexy without implants was performed in 5. No major complications was observed, 4 had minor complications during the postoperative period. Discussion: This series presents similar results to those described by other authors. Conclusions: The Upper Body Lift offers comprehensive and successful management in patients with large upper body disturbance.
导语:肥胖患者通过体重的大幅减轻,获得了有益的健康效果,但却产生了过多的多余皮肤,成为影响生活质量的身体问题。在严重的情况下,传统的身体轮廓技术无法解决这种大的改变,需要使用更广泛的程序。上半身举是一种提供整体管理上躯干的技术。目的:描述一组接受上半身提术的病人,并介绍手术技巧。材料与方法:选取2013年1月至2016年6月在某临床医院进行上半身提升术的前瞻性病例系列。排除信息不完整或在其他中心手术的患者。采用描述性统计。结果:纳入8例患者,年龄39.75±9.37岁,女性6例(75%)。在整形手术之前,他们减掉了36.75±9.11 kg, BMI达到25.97±2.35 kg/m2。男性胸部部位采用吸脂和乳头移植,女性乳房切除术不采用植入物。术后无重大并发症,4例出现轻微并发症。讨论:本系列给出了与其他作者描述的结果相似的结果。结论:上半身提升术是治疗上半身严重障碍的有效方法。
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引用次数: 0
Enfermedad multianeurismática: a propósito de un caso 多动脉瘤疾病:关于一个病例
Q4 Medicine Pub Date : 2018-09-20 DOI: 10.4067/s0718-40262018000500452
Isabel María Manosalbas-Rubio, E. Doiz-Artázcoz, Ana Margarita Ruales-Romero, M. Rodríguez-Piñero
Introduction: Multiple artery aneurysms are a rare pathological condition which may be caused by different etiologies. Therefore, its location, morphology and clinical presentation may vary in a case to case basis. Case report: A 51-year-old woman, prior history of dyslipedemia presents with upper abdominal pain. Abdominal tomographic scans showed aneurysm of the pancreaticduodenal artery and retroperitoneal hematoma. Emergent surgical evacuation of the hematoma was performed, with no other findings. In the postoperative period, the patient suffers hypertensive crisis and a new tomographic scan is conducted observing multiple dilations in different visceral arteries. The patient is treated conservatively and is being studied for a possible vasculitis. Discussion: Multi-aneurysmatic artery disease is a very rare entity, its etiology is determined by clinical and histopathological correlation. Although establishing a diagnosis in which the clinical presentation completely corresponds, is a real challenge. Unlike degenerative aneurysms due to atherosclerosis, multi-aneurysmatic disease commonly involves visceral arteries. Open surgery is considered safe treatment option and should be established in the segments causing symptoms. Endovascular treatment is less invasive, being the technique of choice in patients with high comorbidity and in cases of complicated surgery with rupture.
摘要多动脉动脉瘤是一种罕见的疾病,其病因多种多样。因此,其位置、形态和临床表现可能因病例而异。病例报告:一名51岁女性,既往有血脂异常史,表现为上腹部疼痛。腹部断层扫描显示胰十二指肠动脉动脉瘤及腹膜后血肿。紧急手术清除血肿,无其他发现。术后患者出现高血压危象,进行新的断层扫描,观察到不同内脏动脉多发扩张。患者接受保守治疗,目前正在研究是否有血管炎。讨论:多动脉瘤性动脉疾病是一种非常罕见的疾病,其病因取决于临床和组织病理学的相关性。虽然建立一个诊断与临床表现完全相符,是一个真正的挑战。与动脉粥样硬化引起的退行性动脉瘤不同,多动脉瘤疾病通常累及内脏动脉。开放手术被认为是安全的治疗选择,应该在引起症状的节段建立。血管内治疗创伤小,是高合并症患者和复杂手术破裂患者的首选技术。
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引用次数: 0
Cáncer de mama avanzado receptor de estrógeno positivo: Manejo sistémico actual 晚期乳腺癌雌激素受体阳性:目前的全身治疗
Q4 Medicine Pub Date : 2018-09-20 DOI: 10.4067/S0718-40262018000500463
R. Sánchez, V. Valenzuela, Alejandra Pérez-Sepúlveda, P. Villarroel, A. Medina, A. Camus, C. Acevedo
Breast cancer is the leading cause of cancer death in Chilean women. While most patientes are cured, five percent of cases present with advanced disease initially and up to 20-30% of patients with localized disease may suffer systemic recurrences. The majority of breast neoplasms are dependent on the estrogenic stimulus, hence the deprivation of estrogen is the main therapeutic strategy. Recently, the use of molecular targeted therapies in combination with endocrine therapy has been successful in improving the survival outcomes of advanced breast cancer, with fewer side effects than those produced by conventional chemotherapy. Knowledge of the mechanisms of action of these new therapies, their toxicities, resistance pathways and patient selection to achieve the best therapeutic benefits are relevant aspects in the management of the disease. We present a review of the current state of management of hormone-dependent metastatic breast cancer with emphasis on the use of endocrine therapies combined with molecular therapies.
乳腺癌是智利妇女癌症死亡的主要原因。虽然大多数患者被治愈,但5%的病例最初表现为晚期疾病,高达20-30%的局部疾病患者可能出现全身复发。大多数乳腺肿瘤依赖于雌激素刺激,因此剥夺雌激素是主要的治疗策略。近年来,分子靶向治疗联合内分泌治疗在改善晚期乳腺癌的生存结果方面取得了成功,而且副作用比传统化疗少。了解这些新疗法的作用机制、它们的毒性、耐药途径和选择患者以获得最佳治疗效果是疾病管理的相关方面。我们介绍了激素依赖性转移性乳腺癌的管理现状,重点是内分泌治疗结合分子治疗的使用。
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引用次数: 2
Centros de simulación quirúrgica regionales y certificación a distancia (telesimulación). Una innovación pionera en el mundo conducida por la Sociedad de Cirujanos de Chile 区域外科模拟和远程认证中心(远程模拟)。智利外科医生协会领导的世界开创性创新
Q4 Medicine Pub Date : 2018-08-01 DOI: 10.4067/S0718-40262018000300307
Nicolás Jarufe, M. Barra, J. Varas
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引用次数: 4
Enfrentando el dilema de las suspensiones: características e incidencia de las suspensiones quirúrgicas en un centro académico en Chile 面对暂停的困境:智利一个学术中心手术暂停的特点和影响
Q4 Medicine Pub Date : 2018-08-01 DOI: 10.4067/S0718-40262018000300322
S Juan Carlos Pattillo, Franklin Dexter
Introduction: Surgical cancellations are a complex problem in the field of Operating Room Management, affecting patients, staff, including surgeons and anesthetists, and compromising the finances of health institutions. The available information about the incidence and characteristics of surgical cancellations in our country are scarce. Objective: The aim of this article is to characterize the surgical cancellations in a Chilean academic center, describing its global incidence and by specialty. Materials and Methods: Prospective information on surgical schedule and Operating Room activity was included in this cohort study of surgical case cancellations occurring from January 1, 2016 through May 20, 2017. To calculate the percentage of cancellations, 3 groups were used based on 6 periods of 4 weeks. The Freeman-Turkey double-arcsine transformation and Student’s t-test were applied. Results: During the study period, 11,398 surgeries were programmed, of which 492 were cancelled. The incidence of cancellations for the 3 periods was 4.38% (95% CI 3.78% to 5.01%), 4.15% (95% CI 3.51% to 4.85%) and 4.10% (95% CI of 3.50% to 4.74%) respectively. In at least 57% of cases the main identifiable cause of cancellation was a change in the patient’s medical condition. Discussion and Conclusions: Our results consistently show that the cancellation rates range between 3% and 5%, which is within international standards, and can be used as benchmarking for comparisons at a national level.
引言:手术取消是手术室管理领域的一个复杂问题,影响患者、工作人员,包括外科医生和麻醉师,并影响卫生机构的财务。关于我国手术取消的发生率和特点的现有信息很少。目的:本文的目的是描述智利学术中心的手术取消情况,描述其全球发病率和专业。材料和方法:本队列研究纳入了2016年1月1日至2017年5月20日期间取消手术的手术计划和手术室活动的前瞻性信息。为了计算取消的百分比,基于4周的6个时段使用了3组。应用Freeman-Turkey双反正正弦变换和Student t检验。结果:在研究期间,共安排了11398例手术,其中492例被取消。3个时期的取消发生率分别为4.38%(95%CI 3.78%至5.01%)、4.15%(95%CI 3.51%至4.85%)和4.10%(95%CI为3.50%至4.74%)。在至少57%的病例中,取消的主要可识别原因是患者的医疗状况发生了变化。讨论和结论:我们的结果一致表明,取消率在3%至5%之间,在国际标准范围内,可以作为国家层面比较的基准。
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引用次数: 2
Paresia gástrica masiva como único hallazgo diagnóstico de linitis plástica por carcinoma de células en anillo de sello 巨大胃轻瘫是印戒细胞癌塑性阴道炎的唯一诊断发现
Q4 Medicine Pub Date : 2018-08-01 DOI: 10.4067/s0718-40262018000300313
Aingeru Sarriugarte-Lasarte, O. Gutiérrez-Grijalba, I. Álvarez-Abad, Miguel Calle-Baraja
Mujer de 54 años que consultó en urgencias por vómitos realizándose Rx abdominal y TC (Figura 1) donde se aprecia una gran distensión gástrica. Tras descompresión nasogástrica se realizó gastroscopia sin hallazgos de neoplasia ni obstrucción mecánica de otra causa. El estudio de biopsias aleatorias mostró infiltración por carcinoma con células en anillo de sello. Se intervino para gastrectomía total con hallazgo de linitis plástica (Figura 2). El carcinoma difuso de células en anillo de sello es un tumor cada vez más frecuente que difunde por la submucosa hasta convertirse en transmural con rapidez dando una imagen macroscópica de linitis plástica y respetando en algunas ocasiones la mucosa, por lo que es preciso un alto nivel de sospecha clínica para realizar biopsias aleatorias que llevarán al diagnóstico.
一名54岁的妇女因呕吐在急诊室接受腹部X光检查和CT检查(图1),发现胃胀。在鼻胃减压后,进行了胃镜检查,没有发现肿瘤或其他原因的机械梗阻。随机活检研究显示,癌细胞在密封环中浸润。在发现塑料衬里后进行了全胃切除术(图2)。印戒细胞弥漫性癌是一种越来越常见的肿瘤,它通过提供塑料衬里的宏观图像并在某些情况下尊重粘膜,迅速扩散到粘膜下层,成为跨壁肿瘤,因此需要高度的临床怀疑才能进行随机活检,以进行诊断。
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引用次数: 0
Modificación del abordaje quirúrgico en tumores estromales gástricos posterior a neoadyuvancia con Imatinib 伊马替尼新辅助治疗后胃间质肿瘤手术方法的修改
Q4 Medicine Pub Date : 2018-08-01 DOI: 10.4067/S0718-40262018000300342
M. Navarrete, G Dulce Momblán, O Ainitze Ibarzaval, C Ricard Corcelles, M. Jiménez-Toscano, F. A. Lacy
Introduction: The treatment of high-risk gastrointestinal stromal tumors (GIST) is surgical. Results may change when using neoadjuvant. Objetive: To evaluated if the use of neoadjuvant therapy with imatinib can change the surgical approach in high risk gastrointestinal stromal tumors (GIST). Materials and Methods: A retrospective analysis was performed from a prospective collected database in Hospital Clinic of Barcelona between January 2002 and May 2016. Results: A total of 8 patients were analyzed with a mean age of 66.1 ± 13.3 years. The tumor location was upper third 37.5% (3) cases, 50% (4) in the middle third and 12.5% (1) in lower third. Because of high risk classification, location and the need of multivisceral resections, neoadjuvant therapy was indicated. The median time of neoadjuvant therapy was 30 weeks. In 87.5% (7) cases a change of surgical approach was achieved after the use of imatinib. In 100% of our series laparoscopic wedge resection was performed achieving negative margins of resection. The postoperative biopsy showed 51.2% of reduction of initial tumor size, resulting in statistical difference (p < 0.01). All patients are alive and 100% of tumor related survival was achieved. Conclusion: Neoadjuvant therapy maybe can change the surgical approach of patients with high-intermediate risk gastric GIST by reducing tumor size. This response also eventually can achieve optimal oncological outcome.
高危胃肠道间质瘤(GIST)的治疗主要是外科手术。使用新佐剂可能会改变结果。目的:评价伊马替尼新辅助治疗是否能改变高危胃肠道间质瘤(GIST)的手术入路。材料与方法:回顾性分析2002年1月至2016年5月在巴塞罗那医院诊所前瞻性收集的数据库。结果:共分析8例患者,平均年龄66.1±13.3岁。肿瘤位置为上三分之一37.5%(3例),中三分之一50%(4例),下三分之一12.5%(1例)。由于高风险的分类,位置和多脏器切除的需要,新辅助治疗是指。新辅助治疗的中位时间为30周。87.5%(7)例患者在使用伊马替尼后改变手术入路。在我们的系列腹腔镜楔形切除术中,100%的切除边缘为负。术后活检显示肿瘤初始大小缩小51.2%,差异有统计学意义(p < 0.01)。所有患者均存活,肿瘤相关生存率达到100%。结论:新辅助治疗可通过缩小肿瘤大小改变高、中危胃间质瘤患者的手术入路。这种反应最终也能达到最佳的肿瘤预后。
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引用次数: 0
Bases teóricas del uso simulación para el entrenamiento en cirugía 模拟应用于外科训练的理论基础
Q4 Medicine Pub Date : 2018-08-01 DOI: 10.4067/S0718-40262018000300382
Juan Enrique Berner, Ernesto Ewertz
En el contexto clinico actual, diversos factores entorpecen la formacion de medicos y especialistas. La judicializacion de la practica medica, legislaciones que limitan las horas trabajadas, una cultura de trabajo que no admite errores y una mayor demanda por especialistas son desafios que han obligado a docentes a buscar nuevas herramientas. La simulacion permite recrear una situacion clinica, permitiendo al alumno adquirir competencias previo a su aplicacion en la vida real. Este trabajo resume los conceptos actuales en simulacion, las bases teoricas educacionales que explican su utilidad, sus limitaciones y la evidencia disponible sobre su utilizacion.
在当前的临床环境下,有几个因素阻碍了医生和专家的培训。医疗实践的司法化、限制工作时间的立法、不允许错误的工作文化以及对专家需求的增加,都是迫使教师寻找新工具的挑战。模拟允许重现临床情况,让学生在应用到现实生活之前获得技能。本文总结了模拟的当前概念,教育理论基础,解释了它们的有用性,它们的局限性和可用的证据。
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引用次数: 6
Deformidad de la caja torácica 如果你有以下情况,请打电话给你的医生:
Q4 Medicine Pub Date : 2018-08-01 DOI: 10.4067/S0718-40262018000300373
Norman Ramírez-Lluch, José M. Acevedo-Echevarría
Chest wall deformities are divided as an abnormal development during the growth or those secondary to a congenital malformation. The developmental type is the most common: pectus excavatum or pectus carinatum. The less common are the congenital types of chest wall abnormalities: Poland’s syndrome, Jeune’s syndrome, espondylothoracic dysplasia, espondylocostal dysplasia and defects of the ribs or sternum. The congenital type usually affects the relationship between the spine, rib cage and the lungs. Therefore, many of these patients will develop a progressive respiratory disturbance of restrictive type known as Thoracic Insufficiency Syndrome. Thoracic insufficiency syndrome is defining as a deficiency of the rib cage to maintain a normal respiration and to sustain the physiological growth of the lungs. In this article will discuss several conditions that will affect the development and function of the chest wall.
胸壁畸形分为生长过程中的异常发育或继发于先天性畸形。发育型是最常见的:漏斗胸或隆突胸。较不常见的是先天性胸壁异常类型:波兰综合征,Jeune综合征,胸膜髁发育不良,胸膜髁发育不良以及肋骨或胸骨缺陷。先天性型通常影响脊柱、胸腔和肺部之间的关系。因此,这些患者中的许多人将发展为进行性限制性呼吸障碍,称为胸功能不全综合征。胸功能不全综合征被定义为胸腔功能不足,无法维持正常呼吸和肺的生理生长。本文将讨论影响胸壁发育和功能的几种情况。
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引用次数: 0
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Revista Chilena De Cirugia
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