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Independent risk factors associated with a history of exercise associated muscle cramps (EAMC) among 21460 cycling race entrants (SAFER XXXVI): a descriptive cross-sectional study 21460名自行车比赛参赛者(SAFER XXXVI)中与运动相关性肌肉痉挛(EAMC)病史相关的独立危险因素:一项描述性横断面研究
IF 3.2 3区 医学 Q1 ORTHOPEDICS Pub Date : 2025-12-18 DOI: 10.1016/j.bjpt.2025.101559
Carey Pohl , Martin Schwellnus , Nicola Sewry , Pieter Boer , Esme Jordaan , Carel Viljoen

Background

There is limited research on cyclists with a history of exercise associated muscle cramps (hEAMC) defined as muscle cramping (painful, spontaneous, sustained spasm of a muscle) during or after cycling.

Objective

To determine the epidemiology, clinical characteristics, and risk factors associated with hEAMC in cyclists taking part in a mass participation cycling event.

Methods

21,460 race entrants from the 2016 Cape Town Cycle Tour completed an online questionnaire, which is based on the guidelines for recreational exercise participation from the European Association of Cardiovascular Prevention and Rehabilitation [EACPR]. The main outcome measures were: the lifetime prevalence hEAMC (%; 95% confidence intervals), independent risk factors (adjusted for age and sex) associated with hEAMC (history of chronic disease, history of allergies, history of chronic medication use, history of medication use before and during race, history of cycling injuries, and cycling training/racing variables). Poisson regression was used to calculate the prevalence (%) of the variables of interest, with 95% confidence intervals.

Results

The retrospective lifetime prevalence of hEAMC was 30.51%. EAMC in cyclists affects mainly the quadriceps muscles and occurs in the 4th quarter during a race. Novel independent risk factors associated with an increased risk of hEAMC in cyclists were: increased number of years participating as a recreational cyclist (PR=1.03 per 5 years increase; p<0.0001), a higher chronic disease composite score (PR=1.36 times increased risk for every 2 additional chronic diseases; p<0.0001), a history of any allergies (PR=1.18; p<0.0001), medication use before or during event (PR=1.41; p<0.0001) a history of an acute (PR=1.30; p<0.0001) and gradual onset injury (PR=1.29; p<0.0001).

Conclusion

Our study identified novel independent risk factors associated with a hEAMC. These results, in combination with other known risk factors, could assist future targeted prevention programmes and the management of EAMC in recreational cyclists.
研究背景:对于有运动相关性肌肉痉挛(hEAMC)病史的骑车者的研究有限,hEAMC定义为骑车期间或之后的肌肉痉挛(肌肉疼痛、自发、持续的痉挛)。目的探讨参加大众参与自行车赛事的自行车运动员hEAMC的流行病学、临床特征及相关危险因素。方法21460名参加2016年开普敦自行车巡回赛的参赛者根据欧洲心血管预防和康复协会(EACPR)的娱乐运动参与指南完成了一份在线问卷。主要结局指标为:hEAMC的终生患病率(%,95%可信区间)、与hEAMC相关的独立危险因素(经年龄和性别调整)(慢性病史、过敏史、慢性用药史、比赛前和比赛期间用药史、骑行损伤史和骑行训练/比赛变量)。使用泊松回归计算感兴趣变量的患病率(%),置信区间为95%。结果hEAMC的回顾性终生患病率为30.51%。骑车者的EAMC主要影响四头肌,发生在比赛中的第四节。与骑行者hEAMC风险增加相关的新的独立危险因素是:作为休闲骑行者参加骑行的年数增加(PR=1.03 / 5年增加;p<0.0001),较高的慢性疾病综合评分(PR=1.36倍,每增加2个慢性疾病的风险增加;p<0.0001),任何过敏史(PR=1.18; p<0.0001),活动前或期间使用药物(PR=1.41; p<0.0001),急性史(PR=1.30;p =1.29; p = 0.0001)和渐发性损伤(p = 0.0001)。结论:我们的研究发现了与hEAMC相关的新的独立危险因素。这些结果,结合其他已知的风险因素,可以帮助未来有针对性的预防规划和管理休闲骑自行车者的EAMC。
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引用次数: 0
Blockade of opioid receptors prevents the effect of exercise on neuropathic pain in mice, promoting immunoregulation in the brainstem and prefrontal cortex 阻断阿片受体可阻止运动对小鼠神经性疼痛的影响,促进脑干和前额叶皮层的免疫调节
IF 3.2 3区 医学 Q1 ORTHOPEDICS Pub Date : 2025-12-18 DOI: 10.1016/j.bjpt.2025.101561
Fernanda Belle , Elisa Mitkus Flores Lins , Josiel Mileno Mack , Francielly Suzaine da Silva , Ludmilla Solange Gelain , Verônica Vargas Horewicz , Guilherme de Azevedo Traebert , Alexandre Carlos Buffon , Deborah de Camargo Hizume-Kunzler , Daniel Fernandes Martins , Franciane Bobinski

Background

Physical exercise is widely recognized for reducing neuropathic pain. However, the interaction between the immune and opioidergic systems in supraspinal structures is still not fully understood.

Objective

To evaluate the impact of opioid receptor blockade on the effects of low-intensity exercise on the sensory, cognitive, and emotional aspects of neuropathic pain after sciatic nerve injury.

Methods

Male Swiss mice (2 months old) were submitted to sciatic nerve crush and divided into sedentary or exercised groups. The exercised groups performed treadmill running for two weeks, with or without naloxone pre-treatment to block opioid receptors. Sensory responses were assessed using the von Frey test, while cognitive and emotional-like behaviors were evaluated through the Mechanical Conflict-Avoidance System (MCAS) and open field test, respectively. Cytokine levels (IL-4, IL-10) and brain-derived neurotrophic factor (BDNF) were quantified in the brainstem and prefrontal cortex by ELISA.

Results

Exercise reduced mechanical hypersensitivity and improved performance in cognitive and exploratory tasks. These effects were prevented by naloxone administration. Exercise also increased IL-4, IL-10, and BDNF levels in supraspinal regions, while naloxone reversed these changes, indicating the involvement of μ-opioid receptors in exercise-induced immunomodulation.

Conclusion

Low-intensity exercise promotes analgesia and neuroimmune regulation in neuropathic pain through supraspinal μ-opioid receptor activation. The blockade of these receptors abolishes the beneficial effects of exercise, reinforcing the interaction between opioidergic and immune systems in pain modulation.
体育锻炼被广泛认为可以减轻神经性疼痛。然而,棘上结构中免疫系统和阿片能系统之间的相互作用仍未完全了解。目的探讨阿片受体阻断对低强度运动对坐骨神经损伤后神经性疼痛的感觉、认知和情绪方面的影响。方法将2月龄的瑞士小白鼠进行坐骨神经压迫实验,分为运动组和久坐组。运动组在跑步机上跑步两周,有或没有纳洛酮预处理来阻断阿片受体。感官反应采用von Frey测试,认知行为和情感行为分别采用机械冲突避免系统(MCAS)和开放场测试进行评估。ELISA法测定大鼠脑干和前额叶皮层细胞因子(IL-4、IL-10)和脑源性神经营养因子(BDNF)水平。结果运动降低了机械过敏,提高了认知和探索性任务的表现。纳洛酮可预防这些影响。运动还增加了棘上区IL-4、IL-10和BDNF的水平,而纳洛酮逆转了这些变化,表明μ-阿片受体参与了运动诱导的免疫调节。结论低强度运动通过激活棘上μ-阿片受体促进神经性疼痛的镇痛和神经免疫调节。这些受体的阻断消除了运动的有益作用,加强了阿片能和免疫系统在疼痛调节中的相互作用。
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引用次数: 0
Type of health locus of control predicting pain, function, and global perceived effect in patients with chronic low back pain receiving active versus passive interventions: an observational study 慢性腰痛患者接受主动与被动干预的健康控制点类型预测疼痛、功能和整体感知效应:一项观察性研究
IF 3.2 3区 医学 Q1 ORTHOPEDICS Pub Date : 2025-12-18 DOI: 10.1016/j.bjpt.2025.101560
Ivan de Araujo Barros , Arthur de Sá Ferreira , Thaís de Souza Horsth , Thamires de Jesus Holmes , Anna Amalheiro dos Santos , Luciana Crepaldi Lunkes

Introduction

Chronic nonspecific low back pain (CNLBP) is the leading cause of disability worldwide. The health locus of control (HLC) refers to the individual's perception of control over their health, which can be internal (personal control), external (control attributed to others), or chance (determined by luck, fate, or chance).

Objective

To investigate whether the HLC predicts pain, functional ability, and global perceived effect in patients with CNLBP treated with active versus passive interventions.

Methods

Longitudinal observational study following two different treatments groups delivered by physical therapists: active group (exercise-based intervention) and passive group (manual therapy-based intervention). The HLC was assessed with the Multidimensional Health Locus of Control Scale (MHLCS), pain with the Pain Numerical Rating Scale (PNRS), functional ability with the Patient-Specific Functional Scale (PSFS), and global perceived effect by the Global Perceived Effect Scale (GPES). The relationship between the types of HLC at baseline and after the intervention was analyzed by the Chi-square test, and the prediction of outcomes by linear regression (p < 0.05).

Results

Fifty-eight individuals participated, with a mean age of 51.2 (5.6) years. There was no impact of baseline HLC on pain, functional ability, or global perceived effect (p > 0.05), and there were no significant changes in HLC at the endpoint of observation (p = 0.75).

Conclusion

HLC was not a predictor for the evaluated outcomes, with no significant changes between baseline and the endpoint of observation.
慢性非特异性腰痛(CNLBP)是全球致残的主要原因。健康控制点(health locus of control, HLC)是指个体对自身健康控制的感知,这种控制可以是内部(个人控制)、外部(归因于他人的控制)或偶然(由运气、命运或机会决定)。目的探讨HLC是否能预测CNLBP患者接受主动和被动干预后的疼痛、功能能力和整体感知效果。方法采用纵向观察研究方法,观察由物理治疗师提供的两个不同治疗组:主动组(以运动为基础的干预)和被动组(以手工治疗为基础的干预)。采用多维健康控制点量表(MHLCS)、疼痛评定量表(PNRS)、功能能力评定量表(PSFS)和整体感知效应量表(GPES)对患者的整体感知效应进行评估。采用卡方检验分析干预前后HLC类型的关系,采用线性回归预测结果(p < 0.05)。结果58人参与,平均年龄51.2(5.6)岁。基线HLC对疼痛、功能能力或整体感知效果无影响(p > 0.05),观察终点时HLC无显著变化(p = 0.75)。结论hplc不是评估结果的预测因子,在基线和观察终点之间没有显著变化。
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引用次数: 0
Foot-specific exercise intervention for forefoot deformity in individuals with type 2 diabetes and peripheral neuropathy: A randomized controlled clinical trial with 3-year follow-up 足部特异性运动干预治疗2型糖尿病和周围神经病变患者的前足畸形:一项3年随访的随机对照临床试验
IF 3.2 3区 医学 Q1 ORTHOPEDICS Pub Date : 2025-12-17 DOI: 10.1016/j.bjpt.2025.101563
JA Zellers , K Steger-May , PK Commean , H-J Jeong , EM Bullard , MJ Mueller , MK Hastings

Background

Diabetes with peripheral neuropathy can lead to metatarsophalangeal joint (MTPJ) deformity. The purpose of this study was to estimate the effect of a foot-specific intervention on MTPJ deformity. Secondary aims were determining MTPJ deformity progression over 3 years and predictors of MTPJ deformity progression.

Methods

Sixty people with type 2 diabetes and peripheral neuropathy were recruited for this randomized controlled clinical trial. Participants were assessed at baseline, 6 months (post-intervention), 1.5 years, and 3 years. A 6-month, foot-specific intervention in the experimental group was compared to a shoulder intervention in the control group. The primary outcome was change in 2nd MTPJ angle assessed with computed tomography (CT).

Results

There was no effect of intervention on 2nd MTPJ angle (main effect of group p = 0.56, main effect of visit p = 0.56, group*visit interaction p = 0.79). In combined experimental and control groups, 26 % and 9 % of participants met the cutoff threshold for MTPJ angle progression at 1.5 and 3 years, respectively. Change in 2nd metatarsal bone mineral density from baseline to 3 years predicted 2nd MTPJ angle progression at 3 years (Rescaled R2 = 0.22, p = 0.01).

Conclusion

The study intervention was unable to yield a detectible improvement in 2nd MTPJ angle. The intervention may not have been of sufficient intensity to induce positive changes or there may be limited capacity for the neuropathic foot to respond to traditional modes of exercise. While useful in improving other outcomes, exercise-based intervention may not be an effective method of reducing or delaying forefoot deformity progression.
背景:糖尿病伴周围神经病变可导致跖趾关节(MTPJ)畸形。本研究的目的是评估足部特异性干预对MTPJ畸形的影响。次要目的是确定3年内MTPJ畸形进展和MTPJ畸形进展的预测因素。方法:60例2型糖尿病和周围神经病变患者被招募进行随机对照临床试验。在基线、6个月(干预后)、1.5年和3年对参与者进行评估。实验组进行了为期6个月的针对足部的干预,对照组进行了肩部干预。主要观察指标为CT评估的第2 MTPJ角度的变化。结果:干预对第2 MTPJ角无影响(组主效应p = 0.56,访视主效应p = 0.56,组与访视交互作用p = 0.79)。在联合实验组和对照组中,26%和9%的参与者分别在1.5年和3年达到MTPJ角度进展的临界值。从基线到3年第二跖骨骨密度的变化预测了3年第2 MTPJ角的进展(重新校正R2 = 0.22, p = 0.01)。结论:研究干预不能明显改善第2 MTPJ角。干预可能没有足够的强度来诱导积极的变化,或者神经性足对传统运动模式的反应能力有限。虽然在改善其他结果方面有用,但基于运动的干预可能不是减少或延迟前足畸形进展的有效方法。
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引用次数: 0
Assessing postural control deficits with the Balance Evaluation Systems test for children, second edition in children with Developmental Coordination Disorder 用儿童平衡评估系统测试评估姿势控制缺陷,第二版儿童发育协调障碍。
IF 3.2 3区 医学 Q1 ORTHOPEDICS Pub Date : 2025-12-17 DOI: 10.1016/j.bjpt.2025.101558
Maja Van Grinderbeek , Katrijn Klingels , Mieke Goetschalckx , Charlotte Johnson , Silke Velghe , Ann Hallemans , Evi Verbecque

Background

Postural control deficits are highly prevalent in children with Developmental Coordination Disorder (DCD). We developed an extended, age-specific version of the Balance Evaluation Systems test for children (Kids-BESTest-2; age 5–12) that allows for the identification of specific deficient postural control systems by assessing corresponding postural control test domains.

Objective

To assess the clinical value of the Kids-BESTest-2 in identifying postural control deficits in children with Developmental Coordination Disorder (DCD) by evaluating its construct and predictive validity.

Methods

We included 89 typically developing (TD) children and 66 children with DCD (age 5–12). Construct validity was established by: 1) exploring differences in Kids-BESTest-2 scores between the known groups (DCD/TD) using the Mann-Whitney U test, 2) determining internal relationships and relationships with child-specific factors with the Spearman rank correlations. Predictive validity was investigated with binary logistic regression analysis.

Results

TD children outperformed (p<0.001) their DCD peers on the Kids-BESTest-2. The Kids-BESTest-2 correlates moderately (ρ=0.69–0.78, p<0.001) to strongly (ρ=0.79–0.88, p<0.001) with domain scores. The Kids-BESTest-2 total score significantly correlates with the MABC-2 total score (ρ= 0.62, p<0.001), the MABC-2 balance score (ρ=0.64, p<0.001), and age (ρ=0.40, p<0.001). Age and MABC-2 total and balance scores predict a Kids-BESTest-2 total score < 80%, with a 92.0% sensitivity, 92.9% specificity.

Conclusions

The Kids-BESTest-2 is a valid tool to identify and specify postural control deficits in children with DCD. Clinicians can decide to administer the Kids-BEST-test-2 by using age and MABC-2 total and balance scores to predict performance.
背景:体位控制缺陷在发育性协调障碍(DCD)患儿中非常普遍。我们为儿童(kids - bestst -2; 5-12岁)开发了一个扩展的、针对特定年龄的平衡评估系统测试,通过评估相应的姿势控制测试域,可以识别出特定的姿势控制系统缺陷。目的:通过评价kids - best -2量表的结构和预测效度,评价其在识别发育协调障碍(DCD)儿童姿势控制缺陷中的临床应用价值。方法:我们纳入89例典型发育(TD)儿童和66例DCD儿童(5-12岁)。构建效度的建立是通过:1)使用Mann-Whitney U检验探索已知组(DCD/TD)之间kids - best -2得分的差异,2)使用Spearman秩相关来确定内部关系以及与儿童特定因素的关系。预测效度采用二元logistic回归分析。结论:kids - best -2是识别和明确DCD患儿姿势控制缺陷的有效工具。临床医生可以通过使用年龄和MABC-2总分和平衡分数来预测表现,从而决定实施儿童最佳测试2。
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引用次数: 0
Assessing postural balance for predicting falls in individuals with Chronic obstructive pulmonary disease: A prospective cohort study 评估体位平衡预测慢性阻塞性肺疾病患者跌倒:一项前瞻性队列研究
IF 3.2 3区 医学 Q1 ORTHOPEDICS Pub Date : 2025-12-13 DOI: 10.1016/j.bjpt.2025.101557
Bárbara Aparecida Teodoro Alcantara Verri , Caroline Maschio de Censo , Juliana de Melo Batista dos Santos , Rafaella Fagundes Xavier , João Marcos Salge , Regina Maria Carvalho-Pinto , Celso Ricardo Fernandes Carvalho

Background

Individuals with severe Chronic Obstructive Pulmonary Disease (COPD) have a higher risk of falls while performing physical activities; however, assessments to distinguish who falls are lacking.

Objective

To assess postural balance under challenging conditions to discriminate individuals who experience a fall.

Methods

Patients with moderate to very severe COPD were recruited and performed postural balance assessment. The centre of pressure (COP) was measured using a force platform under different conditions: at rest, post-effort, semi-tandem, and semi-tandem+post-effort. Individuals received a fall diary and were monitored during six months by phone calls. After the follow-up period, patients who experienced a fall were included in the Falls Group (FG) and those who did not were included in the Non-Falls Group (NFG). Receiver operating characteristic (ROC) curves were constructed, and the area under the curve (AUCs) was calculated to assess the predictive value of postural strategies.

Results

Individuals with COPD (n = 61); FG (n = 26) and NFG (n = 35) were included. Compared with NFG, FG presented greater path length (42.5 [34.1, 54.7] vs. 34.1 [29.2, 42.5]cm) and COP-AP (2.60 [2.10, 3.50] vs. 2.10 [1.70, 2.60]cm) in post-effort position. In the semi-tandem position, FG presented greater COP-ML than NFG (3.00 [2.50, 4.00] vs. 2.50 [2.20, 3.00]cm). FG also presented a greater path length (82.1 [67.4, 136.9] vs. 67.4 [56.3, 82.1]cm), COP-ML (3.70 [2.90, 5.50] vs. 2.90 [2.10, 3.70]cm), and COP-AP (3.80 [3.10, 5.00] vs. 3.10 [2.10, 3.80]cm) than NFG did in semi-tandem post-effort position. In total, 100 falls were reported, most of which occurred inside the patient's home (65 %) and while individuals were walking (48 %).

Conclusion

Assessing postural balance in challenging positions can discriminate between individuals with severe COPD who experience a fall.
背景:患有严重慢性阻塞性肺疾病(COPD)的个体在进行体育活动时摔倒的风险更高;然而,缺乏区分谁跌倒的评估。目的:评估具有挑战性条件下的姿势平衡,以区分经历跌倒的个体。方法:招募中度至极重度COPD患者并进行姿势平衡评估。使用力平台测量不同条件下的压力中心(COP):静息、用力后、半串联、半串联+用力后。参与者收到了一份秋季日记,并在六个月内通过电话进行监控。随访结束后,有跌倒经历的患者被纳入跌倒组(FG),没有跌倒经历的患者被纳入非跌倒组(NFG)。构建受试者工作特征(ROC)曲线,计算曲线下面积(auc),评估姿势策略的预测价值。结果:COPD患者(n = 61);包括FG (n = 26)和NFG (n = 35)。与NFG相比,FG在努力后位置的路径长度(42.5[34.1,54.7]比34.1 [29.2,42.5]cm)和COP-AP(2.60[2.10, 3.50]比2.10 [1.70,2.60]cm)更长。在半串联体位,FG比NFG出现更大的COP-ML (3.00 [2.50, 4.00] vs. 2.50 [2.20, 3.00]cm)。FG的路径长度(82.1[67.4,136.9]比67.4 [56.3,82.1]cm), COP-ML(3.70[2.90, 5.50]比2.90 [2.10,3.70]cm)和COP-AP(3.80[3.10, 5.00]比3.10 [2.10,3.80]cm)也比NFG在半双人运动后的位置上更长。总共报告了100例跌倒,其中大多数发生在患者家中(65%)和个人行走时(48%)。结论:评估挑战性体位的姿势平衡可以区分患有严重COPD的跌倒患者。
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引用次数: 0
Effectiveness of exercise interventions to improve motor coordination and manual dexterity of deaf children: A systematic review and meta-analysis of randomized controlled trials 运动干预提高聋儿运动协调性和手灵巧性的有效性:随机对照试验的系统回顾和荟萃分析
IF 3.2 3区 医学 Q1 ORTHOPEDICS Pub Date : 2025-11-21 DOI: 10.1016/j.bjpt.2025.101556
Renato S. Melo , Ilana Santos de Oliveira , Cleysiane de Araújo Oliveira , Alexandre Delgado , Karla Mônica Ferraz , Rosalie Barreto Belian

Background

Vestibular disorders are frequent findings in children with sensorineural hearing loss (SNHL), impairing the sensory regulation of postural control, and the spatiotemporal relationship, and triggering disturbances in balance, motor coordination, and gross and fine motor skills in these children.

Objective

To assess the certainty of evidence from randomized controlled trials (RCTs) that used exercise interventions to improve motor coordination and manual dexterity of children and/or adolescents with SNHL.

Methods

This systematic review searched for articles on the topic in 10 electronic databases: MEDLINE/Pubmed, SCOPUS, EMBASE, Web of Science, CINAHL, LILACS, CENTRAL (Cochrane Central Register of Controlled Trials), PEDro, SciELO and the Google Scholar. There was no restriction on publication time or languages for the selection of articles, and the last search took place on March 1, 2025. RCTs were included, with children and/or adolescents, diagnosed with bilateral SNHL in the age group between 6–19 years old, without physical, cognitive, and/or neurological problems, except vestibular dysfunction, and who used exercise interventions to improve motor coordination and manual dexterity. Three independent reviewers performed the extraction of trials, data, assessment of risk of bias, and certainty of evidence. The presence of risk of bias in RCTs was assessed using the Cochrane risk of bias (RoB) tool and the certainty of the evidence using the GRADE approach.

Results

Eleven RCTs were included in this review with a total of 475 volunteers. Five RCTs were included in the meta-analyses. One of the meta-analyses showed that practicing 18 weeks of exercise improved the general motor coefficient score of the Körperkoordinationstest für Kinder test by 9.08 more in children with SNHL, compared to those who did not exercise: (9.08 [CI:5.78, 12.3], I² = 63 %), based on low certainty evidence. Another meta-analysis observed that practicing exercise for 7 weeks improved the balance of children with SNHL by 6.69 more in the balance subtest of the Bruininks-Oseretsky test of Motor Proficiency, compared to children who did not exercise: (6.69 [CI:4.10, 9.28], I2 = 0 %), based on very low certainty evidence.

Conclusion

Exercise interventions were effective in improving motor coordination and manual dexterity of children with SNHL. However, these findings are not consistent, as they are based on evidence of low or very low certainty. Due to the limitations and biases present in the RCTs analyzed, it is suggested that new RCTs on the topic be performed with greater methodological rigor, to encourage and guide clinical practice on the topic, based on high-certainty evidence.
背景:前庭功能障碍是感觉神经性听力损失(SNHL)患儿的常见症状,损害了体位控制的感觉调节和时空关系,并引发这些患儿的平衡、运动协调、粗细运动技能障碍。目的评估随机对照试验(RCTs)证据的确定性,这些试验使用运动干预来改善SNHL儿童和/或青少年的运动协调和手灵巧性。方法系统检索MEDLINE/Pubmed、SCOPUS、EMBASE、Web of Science、CINAHL、LILACS、CENTRAL (Cochrane CENTRAL Register of Controlled Trials)、PEDro、SciELO和谷歌Scholar等10个电子数据库。文章的选择对出版时间和语言没有限制,最后一次检索发生在2025年3月1日。随机对照试验纳入6-19岁年龄组诊断为双侧SNHL的儿童和/或青少年,除前庭功能障碍外,无身体、认知和/或神经问题,并采用运动干预改善运动协调和手灵巧性。三名独立审稿人进行了试验、数据的提取、偏倚风险评估和证据确定性。使用Cochrane偏倚风险(RoB)工具评估随机对照试验中偏倚风险的存在,使用GRADE方法评估证据的确定性。结果本综述纳入16项随机对照试验,共纳入475名志愿者。meta分析纳入了5项随机对照试验。一项荟萃分析显示,与不运动的儿童相比,进行18周的运动可使SNHL儿童的Körperkoordinationstest f r Kinder测验的一般运动系数得分提高9.08分:(9.08 [CI:5.78, 12.3], I²= 63%),这是基于低确定性证据。另一项荟萃分析发现,与没有锻炼的儿童相比,练习7周的运动可以使SNHL儿童在Bruininks-Oseretsky运动熟练度测试的平衡亚测试中多提高6.69 (6.69 [CI:4.10, 9.28], I2 = 0%),这是基于非常低的确定性证据。结论运动干预能有效改善SNHL患儿的运动协调性和手灵巧性。然而,这些发现并不一致,因为它们是基于低或极低确定性的证据。由于所分析的随机对照试验存在局限性和偏倚,建议在方法上更严格地进行新的随机对照试验,以高确定性证据为基础,鼓励和指导该主题的临床实践。
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引用次数: 0
Effects of behavioral treatment and pelvic floor muscle training on overactive bladder syndrome: a randomized control trial 行为治疗和盆底肌肉训练对膀胱过度活动综合征的影响:一项随机对照试验
IF 3.2 3区 医学 Q1 ORTHOPEDICS Pub Date : 2025-11-06 DOI: 10.1016/j.bjpt.2025.101541
Mayanni Magda Pereira Matias, Fátima Faní Fitz, Márcia Maria Gimenez, Letícia de Azevedo Ferreira, Maria Augusta Tezelli Bortolini, Rodrigo de Aquino Castro

Objective

To evaluate and compare the effects of behavioral treatment (BT) combined with pelvic floor muscle training (PFMT) versus BT and PFMT provided in isolation in women with overactive bladder syndrome (OAB).

Methods

Prospective, randomised, and controlled clinical trial with concealed allocation including 110 women with OAB were randomized into three groups: BT+PFMT, BT, and PFMT. The intervention consisted of 3-month program: BT+PFMT group received an educational program with lifestyle modifications, urgency suppression techniques, bladder training, and motivation strategies, combined with PFMT; BT and PFMT groups carried out the isolated interventions described above. The primary outcome was OAB cure defined by OAB-V8 questionnaire score <8 and the absence of episodes of urgency urinary incontinence in the voiding diary. Secondary outcomes were urinary symptoms, pelvic floor muscle (PFM) function, outpatient and home adherence to the exercise sets, and subjective cure.

Results

Higher objective cure was observed in the BT+PFMT group compared with isolated PFMT and BT in both per protocol and intention-to-treat analyses. In the per protocol analysis, women receiving BT+PFMT were 5.5 times more likely to achieve objective cure than PFMT (OR 5.5; 95% CI 1.6–18.7) and 4.1 times more likely than BT (OR 4.1; 95% CI 1.3–12.8). For the intention-to-treat analysis considering losses as uncured, BT+PFMT remained more effective than PFMT alone (OR 3.4; 95% CI 1.2–9.5). All groups improved PFM function (power, endurance, fast contractions, p < 0.001 for all), however PFMT and PFMT+BT had better PFM function compared to BT group (p < 0.001 for all).

Conclusions

The combination of BT with PFMT were more effective than isolated therapies in the management of female OAB.
目的评价并比较行为治疗(BT)联合盆底肌训练(PFMT)与单独进行盆底肌训练(BT + PFMT)治疗膀胱过度活动综合征(OAB)的效果。方法前瞻性、随机、对照、隐匿分配临床试验纳入110例OAB女性患者,随机分为BT+PFMT组、BT+PFMT组和PFMT组。干预包括3个月的计划:BT+PFMT组接受生活方式改变、紧急抑制技术、膀胱训练和动机策略的教育计划,并结合PFMT;BT和PFMT组进行上述孤立干预。主要终点是OAB- v8问卷得分<;8定义的OAB治愈,排尿日记中没有出现急迫性尿失禁事件。次要结果为泌尿系统症状、盆底肌(PFM)功能、门诊和家庭对锻炼方案的依从性以及主观治愈。结果在方案和意向治疗分析中,BT+PFMT组的客观治愈率均高于单纯PFMT和BT组。在每个方案分析中,接受BT+PFMT的女性实现客观治愈的可能性是PFMT的5.5倍(OR 5.5; 95% CI 1.6-18.7),是BT的4.1倍(OR 4.1; 95% CI 1.3-12.8)。对于考虑未治愈损失的意向治疗分析,BT+PFMT仍然比单独PFMT更有效(OR 3.4; 95% CI 1.2-9.5)。所有组均改善了PFM功能(动力、耐力、快速收缩,p < 0.001),但与BT组相比,PFMT和PFMT+BT组的PFM功能更好(p < 0.001)。结论BT联合PFMT治疗女性OAB比单独治疗更有效。
{"title":"Effects of behavioral treatment and pelvic floor muscle training on overactive bladder syndrome: a randomized control trial","authors":"Mayanni Magda Pereira Matias,&nbsp;Fátima Faní Fitz,&nbsp;Márcia Maria Gimenez,&nbsp;Letícia de Azevedo Ferreira,&nbsp;Maria Augusta Tezelli Bortolini,&nbsp;Rodrigo de Aquino Castro","doi":"10.1016/j.bjpt.2025.101541","DOIUrl":"10.1016/j.bjpt.2025.101541","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate and compare the effects of behavioral treatment (BT) combined with pelvic floor muscle training (PFMT) versus BT and PFMT provided in isolation in women with overactive bladder syndrome (OAB).</div></div><div><h3>Methods</h3><div>Prospective, randomised, and controlled clinical trial with concealed allocation including 110 women with OAB were randomized into three groups: BT+PFMT, BT, and PFMT. The intervention <strong>c</strong>onsisted of 3-month program: BT+PFMT group received an educational program with lifestyle modifications, urgency suppression techniques, bladder training, and motivation strategies, combined with PFMT; BT and PFMT groups carried out the isolated interventions described above. The primary outcome was OAB cure defined by OAB-V8 questionnaire score &lt;8 and the absence of episodes of urgency urinary incontinence in the voiding diary. Secondary outcomes were urinary symptoms, pelvic floor muscle (PFM) function, outpatient and home adherence to the exercise sets, and subjective cure.</div></div><div><h3>Results</h3><div>Higher objective cure was observed in the BT+PFMT group compared with isolated PFMT and BT in both per protocol and intention-to-treat analyses. In the per protocol analysis, women receiving BT+PFMT were 5.5 times more likely to achieve objective cure than PFMT (OR 5.5; 95% CI 1.6–18.7) and 4.1 times more likely than BT (OR 4.1; 95% CI 1.3–12.8). For the intention-to-treat analysis considering losses as uncured, BT+PFMT remained more effective than PFMT alone (OR 3.4; 95% CI 1.2–9.5). All groups improved PFM function (power, endurance, fast contractions, p &lt; 0.001 for all), however PFMT and PFMT+BT had better PFM function compared to BT group (p &lt; 0.001 for all).</div></div><div><h3>Conclusions</h3><div>The combination of BT with PFMT were more effective than isolated therapies in the management of female OAB.</div></div>","PeriodicalId":49621,"journal":{"name":"Brazilian Journal of Physical Therapy","volume":"30 1","pages":"Article 101541"},"PeriodicalIF":3.2,"publicationDate":"2025-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145466147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ANALYZING DISABILITY IN PATIENTS WITH INTERSTITIAL LUNG DISEASES THROUGH THE INTERNATIONAL CLASSIFICATION OF FUNCTIONING, DISABILITY, AND HEALTH FRAMEWORK 通过国际功能、残疾和健康框架分类分析间质性肺疾病患者的残疾
IF 3.2 3区 医学 Q1 ORTHOPEDICS Pub Date : 2025-11-01 DOI: 10.1016/j.bjpt.2025.101292
Wallace Pereira Silva, Giovanna Camargo Mello, Patricia Lira, Ivan Peres Costa, Tatiana Abade, Grasiani Breggue Pires, Soraia Silva, Luciana Maria Malosa Sampaio

Background

Interstitial lung diseases (ILDs) lead to activity limitations and participation restrictions, often resulting in disability. Disability should be assessed using the biopsychosocial model of the International Classification of Functioning, Disability, and Health (ICF), as recommended by the WHO.

Objective

To correlate the ICF domains to explore how bodily functions are associated with activity limitations and participation restrictions in patients with ILD.

Methods

A cross-sectional observational study involving patients with ILD, diagnosed according to the guidelines of the American Thoracic Society (ATS) and the European Respiratory Society (ERS), who had a stable clinical condition for at least three months. Pulmonary function was assessed using spirometry and respiratory muscle strength; activity was measured through the Incremental Shuttle Walk Test (ISWT) and the Six-Minute Walk Test (6MWT); and participation was evaluated using the Saint George's Respiratory Questionnaire (SGRQ).

Results

Of the 25 patients, the majority were men aged over 60 years, and it was observed a positive and moderate correlation (r = 0.45; p < 0.05) was found between activity and pulmonary function. However, the 6MWT showed a negative and moderate correlation with dyspnea (r = -0.52; p = 0.007). The participation component (SGRQ) did not show a significant association with the other components.

Conclusion

A significant relationship was found between the activity component and body functions, whereas participation was not linked to these components. This suggests that restrictions in participation are multifactorial, necessitating a comprehensive approach that goes beyond the traditional biomedical model and includes contextual factors.

Implications

These findings emphasize the need for a biopsychosocial approach in rehabilitation, addressing not only physical function but also social and environmental barriers. Personalized interventions incorporating psychological and social support are essential to effectively enhance participation and patient outcomes.
背景:间质性肺疾病(ild)导致活动受限和参与受限,往往导致残疾。残疾应按照世界卫生组织的建议,使用国际功能、残疾和健康分类(ICF)的生物心理社会模型进行评估。目的通过ICF结构域的相关性,探讨ILD患者的身体功能与活动限制和参与限制之间的关系。方法一项横断面观察性研究,纳入根据美国胸科学会(ATS)和欧洲呼吸学会(ERS)指南诊断的ILD患者,这些患者的临床状况稳定至少三个月。采用肺活量测定法和呼吸肌力量法评估肺功能;通过增量穿梭步行测试(ISWT)和6分钟步行测试(6MWT)测量活动;并使用圣乔治呼吸问卷(SGRQ)评估参与情况。结果25例患者中以60岁以上男性居多,肺活度与肺功能呈正相关(r = 0.45;p < 0.05)。然而,6MWT与呼吸困难呈负相关和中度相关(r = -0.52;p = 0.007)。参与成分(SGRQ)与其他成分没有显著的相关性。结论运动成分与身体功能之间存在显著关系,而参与与这些成分无关。这表明对参与的限制是多因素的,需要一种超越传统生物医学模式并包括环境因素的综合方法。这些发现强调了在康复中需要采用生物心理社会方法,不仅要解决身体功能问题,还要解决社会和环境障碍。结合心理和社会支持的个性化干预措施对于有效提高参与和患者预后至关重要。
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引用次数: 0
IMPACTS OF A PILATES, ZUMBA AND THORACOABDOMINAL REBALANCING PROTOCOL ON THE CARDIORESPIRATORY CONDITIONS OF WOMEN WITH BREAST CANCER: PILOT STUDY 普拉提、尊巴和胸腹再平衡方案对乳腺癌妇女心肺状况的影响:初步研究
IF 3.2 3区 医学 Q1 ORTHOPEDICS Pub Date : 2025-11-01 DOI: 10.1016/j.bjpt.2025.101319
Mariana Clepf Sandrini, Rafaela de Oliveira Martins, Lara da Costa Moreira, Andrew Kenny Araújo dos Santos, Sophia Braga dos Santos, Lívia De Cássia Braz Silveira, Ligia de Souza Marino, Juliana Bassalobre Carvalho Borges
<div><h3>Background</h3><div>Breast cancer represents a relevant health problem both in Brazil and globally, bringing several adverse effects due to treatments, which may include surgeries and/or complementary therapies. Among these consequences, cardiorespiratory changes stand out and require special attention. Therefore, it is essential to develop rehabilitation strategies that promote adherence and effectiveness, through the implementation of a specific and detailed protocol for this population, which includes a combined global training of Mat Pilates, Zumba and Thoracoabdominal Rebalancing with the aim of improving the patients' cardiorespiratory condition.</div></div><div><h3>Objectives</h3><div>To evaluate the impacts of an exercise protocol consisting of Mat Pilates, Zumba and Thoracoabdominal Rebalancing on the cardiorespiratory conditions of women undergoing breast cancer treatment.</div></div><div><h3>Methods</h3><div>Controlled and randomized clinical trial, carried out with women after surgery and undergoing breast cancer treatment, randomized to the intervention group (IG = 8) that received the Zumba, Mat Pilates and Thoracoabdominal Rebalancing protocol and the control group (CG = 8) that did not receive the protocol. The protocol was carried out in 10 sessions, 2 per week on alternate days. Protocol consisting of monitoring initial and final signs (heart rate, diastolic and systolic blood pressure), reeducation of respiratory biomechanics using the Thoracoabdominal Rebalancing Method, 10 minutes of Zumba and 10 minutes of Mat Pilates. Before and after the protocol period, general and clinical characteristics, the physical activity questionnaire (IPAQ) and cardiorespiratory conditions were evaluated considering respiratory muscle strength (maximum inspiratory and expiratory pressures), peripheral muscle strength (handgrip test) and functional capacity using the sit-to-stand test. The variables were analyzed using specific intra (Wilcoxon) and intergroup (Mann-Whitney) statistical tests.</div></div><div><h3>Results</h3><div>The IG was 43.2 ± 7.2 years old and the CG was 59.3 ± 5.5 years old. 75% of the IG and 25% of the CG practiced physical activity. In the intragroup analysis, the IG showed a significant improvement in sit-to-stand test (p = 0.048), while the CG showed a significant worsening in maximum inspiratory pressure (p = 0.039) and in handgrip of the dominant hand (p = 0.030). In the intergroup analysis, there was a significant difference in systolic blood pressure (p = 0.019), with the CG having higher values ??and in the handgrip of the dominant hand (p = 0.048), with the IG having higher values. This indicates that the protocol has the potential to improve or maintain the variables analyzed in the study, since in participants who did not follow the protocol, a reduction in these variables was observed over time.</div></div><div><h3>Conclusion</h3><div>The treatment protocol had a positive impact on the cardiorespiratory
背景乳腺癌在巴西和全球都是一个相关的健康问题,由于治疗,可能包括手术和/或补充疗法,带来了一些不利影响。在这些后果中,心肺变化尤为突出,需要特别注意。因此,制定促进依从性和有效性的康复策略至关重要,通过实施针对这一人群的具体和详细的方案,包括Mat Pilates,尊巴和胸腹再平衡的综合全球培训,以改善患者的心肺状况。目的评价由普拉提、尊巴和胸腹再平衡组成的运动方案对乳腺癌治疗妇女心肺功能的影响。方法对术后接受乳腺癌治疗的女性进行对照和随机临床试验,随机分为干预组(IG = 8)和对照组(CG = 8),干预组接受尊巴、普拉提和胸腹再平衡方案,对照组不接受方案。该方案分10次进行,每周2次,隔天进行。方案包括监测初始和最终体征(心率,舒张压和收缩压),使用胸腹再平衡法进行呼吸生物力学再教育,10分钟尊巴和10分钟普拉提。方案期前后,一般和临床特征,体力活动问卷(IPAQ)和心肺状况评估,考虑呼吸肌力量(最大吸气和呼气压力),外周肌力(握力测试)和功能能力(采用坐立测试)。采用特定的组内(Wilcoxon)和组间(Mann-Whitney)统计检验对变量进行分析。结果IG为43.2±7.2岁,CG为59.3±5.5岁。75%的IG组和25%的CG组进行体育锻炼。在组内分析中,IG组在坐立测试中表现出明显的改善(p = 0.048),而CG组在最大吸气压力(p = 0.039)和优势手握力(p = 0.030)上表现出明显的恶化。在组间分析中,两组患者收缩压差异有统计学意义(p = 0.019),且CG值较高。优势手握(p = 0.048),IG值较高。这表明该方案有可能改善或维持研究中分析的变量,因为在未遵循该方案的参与者中,随着时间的推移,观察到这些变量的减少。结论除维持呼吸和外周肌力变量外,考虑到坐立测试和血压,该治疗方案对大鼠心肺状况有积极影响。而CG组未接受干预的患者,对优势手的吸气和外周肌肉力量有负面影响。结果表明,通过结合特定的和结构良好的锻炼,提高恢复和功能,该方案在改善这一人群的心肺状况方面具有潜力。
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引用次数: 0
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Brazilian Journal of Physical Therapy
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