The Modified Star Excursion Balance Test (mSEBT) was developed as a dynamic postural control test, has been shown to be predictive of lower limb injuries and is consolidated as a valid and reliable measure. However, the relationship between hip variables and mSEBT performance has not been fully elucidated. Deficits in muscle function, flexibility, and range of motion (ROM) of passive medial rotation (MR) of the hip can compromise the performance of mSEBTs.
To verify whether function, flexibility and passive ROM of hip MR predict mSEBT performance in athletes and practitioners of physical activity.
The database of the Physiotherapy Assessment Tool (PHAST) application was used to analyze the records of 125 patients. The relationship of the variables was verified, using multiple linear regression: function of hip extensors, gluteus medius and maximus, the flexibility of iliopsoas, rectus femoris and hamstrings, as well as passive ROM of medial rotation MR hip of the dominant limb with recordings of anterior, posteromedial, and lateral reach distance, as well as mSEBT composite score.
The results revealed a statistically significant model for hip extensor function predicting mSEBT performance in 6% for the composite score (F = 8.07; R = 0.24; R²= 0.062; p = 0.005), in 7% for the posterolateral reach distance (F = 9.18; R = 0.26; R²= 0.070; p = 0.003), by 7% for the posteromedial reach (F = 9.12; R = 0. 26; R²= 0.069; p = 0.003). The association of hip extensor function with gluteus medius function predicted mSEBT performance by 13% for posteromedial reach distance (F = 9.40; R = 0.36; R²= 0.13; p = 0.000). No other associations of hip variables were observed.
Hip extensor function has a statistically significant, but weak, association with mSEBT composite score performance and posterolateral and medial reaching distances. The hip extensor and gluteus medius functions had the highest percentage of prediction, still low, of mSEBT performance for the posteromedial reach.
These findings provide useful information for clinical practice on the contribution of hip musculature functions to mSEBT performance, injury prediction/prevention, and dynamic postural control in athletes and practitioners of physical activities.
The child with Cerebral Palsy (CP) presents different ways of locomotion which are influenced by the environment and can act as a facilitator or a barrier. According to the International Classification of Functioning, Disability, and Health (ICF), capacity refers to abilities in a controlled situation and environment and indicates the maximum level of functionality for a given moment, with minimal influence of environmental factors. On the other hand, performance refers to the execution of activities in everyday environments, such as home, school, and community, considering the environment in which the child is inserted. The difference between capacity and performance expresses the impacts of the controlled environment and the customary environment, allowing guidance on what can be modified in the environment to improve performance.
To verify the relationship between ability and mobility performance in three different environments in children and adolescents with Cerebral Palsy in the Federal District and surroundings.
This is a Cross-sectional study. Thirty-eight children, from age 4 to 17 years old (±7.4 years), diagnosed with CP at all five levels of the Gross Motor Function Classification System (GMFCS) were included. Mobility capacity was verified using the Gross Motor Function Measure test score, version 66 (GMFM-66). Performance was evaluated using the Function Mobility Scale (FMS), in the home, school, and community environments, in 8 levels: 6- independent on all surfaces; 5- independent on ground surfaces; 4- uses canes, 3- crutches; 2- walker; 1- wheelchair; N- does not complete the distances; C - crawls. The sample characteristics were analyzed using descriptive statistics. Spearman (r) correlation was performed between GMFM-66 scores and FMS levels in the three environments (home, school, and community). The strengths of the correlations were determined as follows: r=0.00-0.19 very weak correlation, r=0.20-0.39 weak correlation, r=0.40-0.59 moderate correlation, r=0 .60-0.79 strong correlation, r=0.80-1.00 very strong correlation.
38 children with CP participated, 62% male, 76.5% with bilateral impairment, 26.3% GMFCS V, 15.8% GMFCS IV, 10.5% GMFCS III, 26.3 GMFCS II and 21.1% GMFCS I and 84.2% SUS users (Unified Health System). A strong correlation was found between ability and mobility performance at home (R = 0.726; p <0.001), school (R = 0.726; p< 0.001) and community (R = 0.680; p<0.001) environments.
Results of mobility, ability, and performance are strongly correlated in children and adolescents with cerebral palsy aged 4 to 17 years.
This study demonstrates that children are performing mobility at home, at school, and in the community according to what they are able to accomplish.
Parkinson's disease (PD) is a neurodegenerative disease, chronic and progressive, that produces signs such as tremors at rest, alteration in the functionality of upper limbs (MMSS), and cognitive decline, which impact the performance of activities of daily life. Eccentric exercises have been shown to reduce tremors in people with PD. Nintendo Wii exergames have been used in the rehabilitation of people with PD, promoting improvement in gait, balance, and cognition.
To evaluate the effects of training using Nintendo Wii games in combination with exercises in the upper limb on tremors, upper limb functionality, and the cognition of patients with Parkinson's Disease (PD), compared to training exclusively composed of eccentric upper limb exercises.
This is a randomized, controlled, blinded clinical trial with a sample of 30 people with PD randomly allocated into two groups: Nintendo Wii group combined with eccentric exercises (n=15), who will do 20 minutes of eccentric exercises and 25 minutes of training with Nintendo Wii, and Exclusive eccentric exercises group (n=15), which will do only eccentric exercises for 45 minutes. Both groups will be trained for 8 consecutive weeks, twice a week, totaling 16 sessions. The groups will be evaluated before training, within 7 and 30 days after the end of training.
It was verified in both groups: increase in handgrip strength tends; tremor reduction; improvement of the functional performance of the upper limbs; and improvement in cognitive performance.
The results of this study may contribute to a better understanding of the effectiveness of treatments focused on reducing tremor in patients diagnosed with Parkinson's disease.
The progression of chronic kidney disease (CKD) to its most advanced stage, which usually requires hemodialysis, causes metabolic changes that can impact the neuromuscular system of this population. The difficulty of early detection of CKD often leads to late nephrological referral and initiation of hemodialysis on an emergency basis.
To assess neuromuscular function in people with CKD starting hemodialysis.
Cross-sectional study, evaluating the neuromuscular function in people with CKD admitted to an urgent and emergency hospital who started hemodialysis on an emergency basis (CKD group) compared to people without kidney disease (control group). Measures of neuromuscular excitability (chronaxie obtained in the stimulus electrodiagnostic test), peripheral muscle strength (peak strength focused on lower limb isometric dynamometry) and functional capacity (number of repetitions in the 1-minute sit-to-stand test) were used. To compare the results between the groups, Student's t test was used for variables with normal distribution and the Mann-Whitney test for variables with non-normal distribution, adopting a rejection index of the null hypothesis ≤ 0.05.
Twenty-eight participants, 14 without kidney disease (42 ± 12 years, 5 males and 9 females) and 14 in the CKD group (53 ± 18 years, 9 males and 5 females) were evaluated. The CKD group, compared to controls without kidney disease, showed impairment in neuromuscular excitability (vastus lateralis chronaxie: 654 ± 230 vs 415 ± 190 μs, p = 0.008; tibialis anterior chronaxie: 600 [500 - 1000] vs 400 [300 - 400] μs, p = 0.001), peripheral muscle strength in all muscles assessed (knee extensors: 12. 3 ± 4.6 vs 23.5 ± 9 kgf; knee flexors: 11.3 ± 3.2 vs 17.8 ± 4.3 kgf; dorsiflexors: 8.7 ± 2.8 vs 16.7 ± 4.3 kgf; and plantar flexors: 11.2 ± 2.5 vs 16.6 ± 4.4 kgf, all p < 0.001) and in functional capacity (13.8 ± 4.9 vs 36.7 ± 9.1 repetitions, p < 0.001).
People with advanced CKD who started hemodialysis on an emergency basis have impaired neuromuscular function, considering neuromuscular excitability, lower limb isometric muscle strength and functional capacity.
These findings may guide screening and monitoring strategies for neuromuscular deficiencies and rehabilitation planning.
Gynecological cancers develop in the female reproductive system and include cancer of the cervix, uterus, ovaries, fallopian tubes, vulva, and vagina. High dose rate brachytherapy (BATD) is often used in the treatment of gynecological malignancies, however, it can induce serious side effects of late onset, such as changes in the bowel, urinary tract/bladder and vagina. The practice of physical activity (PA) has positive results on the side effects of gynecological cancer and its treatment.
To compare the level of PA in women who survived gynecological cancer in the first and fourth trimester after BATD at a reference oncology institution in southern Brazil.
Retrospective and longitudinal study based on electronic medical records of women with gynecological cancer treated at the physiotherapy outpatient clinic of the Oncological Research Center (CEPON) in Santa Catarina. The short version of the Physical Activity Questionnaire (IPAQ) was used to assess the level of PA. The collected information was stored in a spreadsheet in Microsoft the IBM SPSS program, version 20.0, was used for statistical analysis. Variables were analyzed descriptively using simple frequency and percentages (categorical variables) and measures of position and dispersion (numerical variables). The Kolmogorov-Smirnov test was performed to verify the normality of the data. To compare the variables related to PA according to the IPAQ (PA time - minutes per day; weekly frequency; sitting time) between the first trimester after radiotherapy and the fourth trimester, the Wilcoxon test was used, with the significance level adopted as 5%.
34 participants were included with a mean age of 53.4 ± 13.5 years. Most were classified as insufficiently active in both the first (55.9%) and fourth (64.7%) trimester after BATD. In addition, an increase in sedentary behavior was identified, with greater relevance in the fourth quarter, so that the average sitting time on a weekday was 147.4±102.4 minutes per day (min/day) in the first quarter to 211.8±125.7 min/day in the fourth quarter (p= 0.007); as well as the average sitting time on a weekend day, increased from 151±103.5 min/day on the first day to 228.5±133.3 min/day (p=0.002).
It was possible to notice that the majority of gynecological cancer survivors do not reach the PA recommendations in the first and fourth trimester after BATD. It was also found that women have sedentary behavior after treatment, especially in the fourth trimester after BATD, spending more time sitting compared to the first quarter.
The study demonstrates the importance of encouraging the practice of physical activity among survivors of gynecological cancer, especially in cancer treatment centers.
Cellular senescence is an irreversible state of cell cycle arrest, thus being characterized by decreased cell proliferation and increased nucleus area, often acting as a tumor suppressor program. Photobiomodulation (PBM) has been used in several conditions to increase the mitochondrial response, promoting nuclear changes and cell proliferation. However, the effects of PBM on cells are still unclear.
To verify the efficacy of photobiomodulation on cell senescence processes.
We utilized A172 glioblastoma cells transduced with H2B-mCherry by lentivirus to nuclear tagging. Treatment was done with GaAIAs Laser (850nm). Cells were divided by intensity into the following groups: C= Control, L1= 1J/cm², L2= 2.2J/cm², L3= 3J/cm², L9= 9J/cm², L15= 15J/cm², L21= 21J/cm², nuclear evaluation was performed at experimental times (0h, 24h, 48h and 72h). For data analysis, two-way ANOVA with the Tukey post hoc test was used. Differences were significant when p<0.05.
PBM on intensities of 1J/cm², 2.2J/cm², 3J/cm², 9J/cm² e 15J/cm² showed a lower increase at the nuclear size when compared with time 0h and 72h in the control group. All intensities (1, 2.2, 3, 9, 15, and 21 J/cm²) promoted cellular proliferation after 72 hours, while 15J/cm² presented an accentuated increase compared to groups L1, L2.2, and L3.
PBM enhanced cellular proliferation while causing a reduced nuclear increase in glioblastoma cells.
In this study, we found that the laser decreased the cellular senescence state from the evaluation of the morphological parameters, thus increasing cell proliferation and decreasing the nuclear area; therefore, it is an important therapeutic tool against the cellular aging process.
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