To investigate the feasibility of robot-assisted computed tomography (CT)–guided percutaneous needle placement compared with the conventional technique.
Materials and Methods
This single-center, open-label, randomized clinical trial included 70 patients with indications for CT-guided intervention, randomly assigned to conventional or robot-assisted groups. A table-mounted robotic system, automated needle-targeting device for CT, was utilized. Needle insertion time, technical success, diagnostic accuracy, procedure duration, needle angle adjustments, number of CT fluoroscopic acquisitions, radiation dose, and adverse event rates were compared.
Results
Seventy patients were enrolled, and 65 patients (33 robot-assisted) were analyzed. Lesion sizes were 44.3 mm (SD ± 26.7) and 43.0 mm (SD ± 28.4) in the conventional and robot-assisted groups, respectively (P = .845). There was no significant difference in the needle insertion time between the 2 groups (175.6 seconds [SD ± 211.8] vs 218.2 seconds [SD ± 242.1], P = .452). Technical success was 100% in both groups. Diagnostic accuracy was 87.0% in the conventional group and 93.3% in the and robot-assisted group (P = .671). Procedure duration was longer in the robot-assisted group (21.4 minutes [SD ± 5.6] vs 33.4 minutes [SD ± 10.3], P < .001). Needle adjustments (2.1 times [SD ± 1.8] vs 0.3 times [SD ± 0.7], P < .001), CT fluoroscopic acquisitions (10.0 times [SD ± 4.9] vs 7.7 times [SD ± 3.4], P = .027), and volume CT dose index (11.2 mGy [SD ± 5.9] vs 8.5 mGy [SD ± 4.7], P = .049) were lower in the robot-assisted group. Dose length product (667.4 mGy·cm [SD ± 247.2] vs 578.5 mGy·cm [SD ± 232.5], P = .143) and adverse event rates (28.1% vs 24.2%, P = .885) were not significant difference between groups.
Conclusions
The robotic system may allow accurate needle insertion across multiple sites, although with prolonged procedure time.
目的:探讨机器人辅助计算机断层扫描(CT)引导下经皮置针技术与传统置针技术的可行性。材料和方法:这项单中心、开放标签、随机临床试验包括70例具有ct引导干预适应症的患者,随机分配到常规组或机器人辅助组。采用台式机器人系统,CT自动针靶装置。我们比较了针头插入时间、技术成功率、诊断准确性、手术时间、针头角度调整、CT透视检查次数、辐射剂量和不良事件发生率。结果:纳入70例患者,分析65例患者(33例机器人辅助)。常规组和机器人辅助组病变大小分别为44.3±26.7 mm和43.0±28.4 mm (p = 0.845)。两组患者插针时间(175.6±211.8 s∶218.2±242.1 s; p = 0.452)差异无统计学意义。两组的技术成功率都是100%。常规组和机器人辅助组的诊断准确率分别为87.0%和93.3% (p = 0.671)。机器人辅助组的手术时间更长(21.4±5.6 vs 33.4±10.3 min; p < 0.001)。机器人辅助组的调针次数(2.1±1.8次vs. 0.3±0.7次,p < 0.001)、CT透视检查次数(10.0±4.9次vs. 7.7±3.4次,p = 0.027)和体积CT剂量指数(11.2±5.9次vs. 8.5±4.7 mGy, p = 0.049)较低。剂量长度乘积(667.4±247.2比578.5±232.5 mGy·cm, p = 0.143)和不良事件发生率(28.1%比24.2%,p = 0.885)组间差异无统计学意义。结论:虽然延长了手术时间,但机器人系统可以在多个部位精确插入针。
{"title":"Feasibility of Robot-Assisted CT-Guided Interventions Compared with Conventional Technique: A Prospective, Randomized, Clinical Trial","authors":"Takafumi Sato MD , Tatsuya Kawai MD, PhD , Junichi Takikawa MS , Keita Nakayama MD, PhD , Shota Ohba MD, PhD , Masashi Shimohira MD, PhD , Kengo Ohta MD, PhD , Kazushi Suzuki MD, PhD , Shinji Kato MD , Yoshinao Ojio MD , Aki Hidari MD , Shunsuke Shibata MD, PhD , Masaya Kisohara MD , Misugi Urano MD, PhD , Takatsune Kawaguchi MD, PhD , Keisuke Hiroshima MD , Ryosuke Horino MD , Ka Wei Ng PhD , Siang Huei Leong PhD , Chow Wei Too MBBS, MMed , Akio Hiwatashi MD, PhD","doi":"10.1016/j.jvir.2025.107925","DOIUrl":"10.1016/j.jvir.2025.107925","url":null,"abstract":"<div><h3>Purpose</h3><div>To investigate the feasibility of robot-assisted computed tomography (CT)–guided percutaneous needle placement compared with the conventional technique.</div></div><div><h3>Materials and Methods</h3><div>This single-center, open-label, randomized clinical trial included 70 patients with indications for CT-guided intervention, randomly assigned to conventional or robot-assisted groups. A table-mounted robotic system, automated needle-targeting device for CT, was utilized. Needle insertion time, technical success, diagnostic accuracy, procedure duration, needle angle adjustments, number of CT fluoroscopic acquisitions, radiation dose, and adverse event rates were compared.</div></div><div><h3>Results</h3><div>Seventy patients were enrolled, and 65 patients (33 robot-assisted) were analyzed. Lesion sizes were 44.3 mm (SD ± 26.7) and 43.0 mm (SD ± 28.4) in the conventional and robot-assisted groups, respectively (<em>P</em> = .845). There was no significant difference in the needle insertion time between the 2 groups (175.6 seconds [SD ± 211.8] vs 218.2 seconds [SD ± 242.1], <em>P</em> = .452). Technical success was 100% in both groups. Diagnostic accuracy was 87.0% in the conventional group and 93.3% in the and robot-assisted group (<em>P</em> = .671). Procedure duration was longer in the robot-assisted group (21.4 minutes [SD ± 5.6] vs 33.4 minutes [SD ± 10.3], <em>P</em> < .001). Needle adjustments (2.1 times [SD ± 1.8] vs 0.3 times [SD ± 0.7], <em>P</em> < .001), CT fluoroscopic acquisitions (10.0 times [SD ± 4.9] vs 7.7 times [SD ± 3.4], <em>P</em> = .027), and volume CT dose index (11.2 mGy [SD ± 5.9] vs 8.5 mGy [SD ± 4.7], <em>P</em> = .049) were lower in the robot-assisted group. Dose length product (667.4 mGy·cm [SD ± 247.2] vs 578.5 mGy·cm [SD ± 232.5], <em>P</em> = .143) and adverse event rates (28.1% vs 24.2%, <em>P</em> = .885) were not significant difference between groups.</div></div><div><h3>Conclusions</h3><div>The robotic system may allow accurate needle insertion across multiple sites, although with prolonged procedure time.</div></div>","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":"37 3","pages":"Article 107925"},"PeriodicalIF":2.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145641960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-01Epub Date: 2025-12-13DOI: 10.1016/j.jvir.2025.107959
Anna Maria Ierardi MD , Velio Ascenti MD , Andrea Gramegna MD, PhD , Francesco Blasi MD, PhD , Costantino Del Giudice MD , Genti Xhepa MD , Filippo Del Grande MD , Massimo Venturini MD, PhD , Gianpaolo Carrafiello MD, PhD , Andrea Coppola MD
Purpose
To compare the effectiveness and safety of bronchial artery embolization using n-butyl-2-cyanoacrylate (nBCA) versus tris-acryl microspheres in patients with cystic fibrosis.
Materials and Methods
Fifty-eight patients with severe hemoptysis (>100 mL/24 h) who underwent endovascular embolization between June 2019 and July 2024 were retrospectively analyzed. Patients were divided into 2 subgroups based on the embolic agent used: nBCA (n = 38) and tris-acryl microspheres (n = 20). Technical success, primary and secondary clinical success, safety, and recurrence rates were evaluated. Potential predictors of recurrence—including the number of pathological arteries identified on computed tomography (CT) angiography, the number and caliber of treated vessels, laterality, and embolized vascular district (bronchial vs nonbronchial systemic arteries)—were assessed using appropriate univariate tests.
Results
Technical success was achieved in all procedures. Primary clinical success was obtained in 57 of 58 patients (98.3%). During follow-up (mean, 42.9 months [SD ± 12.3]), recurrence occurred in 10 of 58 patients (17.2%), with a significantly higher relapse rate in the microsphere group (10 of 20, 50%) and no recurrences in the nBCA group (0 of 38) (P = .0005). Most recurrences (7 of 10) originated from nonbronchial systemic arteries previously embolized with microspheres. No major adverse events were observed. No other variable—including age, number of pathological arteries on CT angiography, vessel caliber, or laterality—showed a significant association with recurrence.
Conclusions
nBCA was associated with lower recurrence rates compared with tris-acryl microspheres. More relapses arose from nonbronchial systemic arteries. Further studies with larger cohorts are needed to confirm these findings and to evaluate additional factors influencing outcomes.
{"title":"Comparison of n-Butyl-2-Cyanoacrylate and Tris-Acryl Microspheres for Bronchial Artery Embolization in Patients with Cystic Fibrosis and Hemoptysis: A Retrospective Cohort Study","authors":"Anna Maria Ierardi MD , Velio Ascenti MD , Andrea Gramegna MD, PhD , Francesco Blasi MD, PhD , Costantino Del Giudice MD , Genti Xhepa MD , Filippo Del Grande MD , Massimo Venturini MD, PhD , Gianpaolo Carrafiello MD, PhD , Andrea Coppola MD","doi":"10.1016/j.jvir.2025.107959","DOIUrl":"10.1016/j.jvir.2025.107959","url":null,"abstract":"<div><h3>Purpose</h3><div>To compare the effectiveness and safety of bronchial artery embolization using <em>n</em>-butyl-2-cyanoacrylate (<em>n</em>BCA) versus tris-acryl microspheres in patients with cystic fibrosis.</div></div><div><h3>Materials and Methods</h3><div>Fifty-eight patients with severe hemoptysis (>100 mL/24 h) who underwent endovascular embolization between June 2019 and July 2024 were retrospectively analyzed. Patients were divided into 2 subgroups based on the embolic agent used: <em>n</em>BCA (n = 38) and tris-acryl microspheres (n = 20). Technical success, primary and secondary clinical success, safety, and recurrence rates were evaluated. Potential predictors of recurrence—including the number of pathological arteries identified on computed tomography (CT) angiography, the number and caliber of treated vessels, laterality, and embolized vascular district (bronchial vs nonbronchial systemic arteries)—were assessed using appropriate univariate tests.</div></div><div><h3>Results</h3><div>Technical success was achieved in all procedures. Primary clinical success was obtained in 57 of 58 patients (98.3%). During follow-up (mean, 42.9 months [SD ± 12.3]), recurrence occurred in 10 of 58 patients (17.2%), with a significantly higher relapse rate in the microsphere group (10 of 20, 50%) and no recurrences in the <em>n</em>BCA group (0 of 38) (<em>P</em> = .0005). Most recurrences (7 of 10) originated from nonbronchial systemic arteries previously embolized with microspheres. No major adverse events were observed. No other variable—including age, number of pathological arteries on CT angiography, vessel caliber, or laterality—showed a significant association with recurrence.</div></div><div><h3>Conclusions</h3><div><em>n</em>BCA was associated with lower recurrence rates compared with tris-acryl microspheres. More relapses arose from nonbronchial systemic arteries. Further studies with larger cohorts are needed to confirm these findings and to evaluate additional factors influencing outcomes.</div></div>","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":"37 3","pages":"Article 107959"},"PeriodicalIF":2.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145758157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
To investigate whether achieving an intraprocedural ice-ball margin of ≥8 mm during percutaneous cryoablation (PCA) of T1b renal cell carcinoma (RCC) results in long-term local tumor control with acceptable adverse events profile.
Materials and Methods
Eighty consecutive patients with biopsy-proven T1b RCC (tumor size, 4.1–7.0 cm) were treated with computed tomography (CT)–guided PCA between 2019 and 2023 at a single center. Outcomes assessed included local tumor progression–free survival (LTPFS), change in renal function (estimated glomerular filtration rate [eGFR]), and adverse events per Society of Interventional Radiology (SIR) criteria. Ice-ball margins were categorized as <8 mm versus ≥8 mm. Kaplan-Meier survival curves and log-rank tests were used for statistical analysis, with significance set at P < .05.
Results
Primary effectiveness was 95% (76 of 80), while secondary effectiveness reached 98.8% (79 of 80) after retreatment of 4 local recurrences. The 24-month LTPFS was 98.8%. Patients with an ice-ball margin ≥8 mm showed a superior 24-month local control (100%) compared with those with 5 to <8 mm margins (57% at 6 months; P = .002). Mean eGFR declined slightly by −2 mL/min/1.73 m2 (P = .125). No SIR Grade 3 or higher adverse events were reported.
Conclusion
PCA is a safe, effective, and nephron-sparing treatment for T1b RCC. Achieving an ice-ball margin of ≥8 mm significantly reduces residual disease and early recurrence.
{"title":"Percutaneous Cryoablation of T1b Renal Tumors: A Retrospective Evaluation of Local Tumor Control, Renal Function Preservation, Adverse Events, and Ablation Margins in 80 Patients","authors":"Antonios Michailidis MD , Panagiotis Kosmoliaptsis MD , Danae Makri MD , George Dimou MD , Evangelos N. Symeonidis MD , Andreas Andreou MD , Stylianos Tegos MD , Apostolos Papalakis MD , Panagiotis Mpalaksis MD , Georgios Moustakas MD , Christos Giankoulof MD , Evangelos Petsatodis MD, PhD","doi":"10.1016/j.jvir.2025.09.025","DOIUrl":"10.1016/j.jvir.2025.09.025","url":null,"abstract":"<div><h3>Purpose</h3><div>To investigate whether achieving an intraprocedural ice-ball margin of ≥8 mm during percutaneous cryoablation (PCA) of T1b renal cell carcinoma (RCC) results in long-term local tumor control with acceptable adverse events profile.</div></div><div><h3>Materials and Methods</h3><div>Eighty consecutive patients with biopsy-proven T1b RCC (tumor size, 4.1–7.0 cm) were treated with computed tomography (CT)–guided PCA between 2019 and 2023 at a single center. Outcomes assessed included local tumor progression–free survival (LTPFS), change in renal function (estimated glomerular filtration rate [eGFR]), and adverse events per Society of Interventional Radiology (SIR) criteria. Ice-ball margins were categorized as <8 mm versus ≥8 mm. Kaplan-Meier survival curves and log-rank tests were used for statistical analysis, with significance set at <em>P</em> < .05.</div></div><div><h3>Results</h3><div>Primary effectiveness was 95% (76 of 80), while secondary effectiveness reached 98.8% (79 of 80) after retreatment of 4 local recurrences. The 24-month LTPFS was 98.8%. Patients with an ice-ball margin ≥8 mm showed a superior 24-month local control (100%) compared with those with 5 to <8 mm margins (57% at 6 months; <em>P</em> = .002). Mean eGFR declined slightly by −2 mL/min/1.73 m<sup>2</sup> (<em>P</em> = .125). No SIR Grade 3 or higher adverse events were reported.</div></div><div><h3>Conclusion</h3><div>PCA is a safe, effective, and nephron-sparing treatment for T1b RCC. Achieving an ice-ball margin of ≥8 mm significantly reduces residual disease and early recurrence.</div></div>","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":"37 3","pages":"Article 107854"},"PeriodicalIF":2.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145126411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-01Epub Date: 2025-11-29DOI: 10.1016/j.jvir.2025.107931
Geert Maleux MD, PhD, Hozan Mufty MD, PhD
{"title":"Limb Graft Occlusion after Translumbar Glue Embolization of a Type II Endoleak","authors":"Geert Maleux MD, PhD, Hozan Mufty MD, PhD","doi":"10.1016/j.jvir.2025.107931","DOIUrl":"10.1016/j.jvir.2025.107931","url":null,"abstract":"","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":"37 3","pages":"Article 107931"},"PeriodicalIF":2.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145649856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-01Epub Date: 2025-11-19DOI: 10.1016/j.jvir.2025.107920
Didier Jourdain BS
Cybersecurity threats to medical imaging systems and workflows are no longer confined to information technology departments; they directly affect interventional radiology (IR) practice, patient safety, and procedural continuity. Two thirds of healthcare organizations experienced ransomware in 2024, with median and mean ransom payments of 1.5 million and 4.4 million dollars, respectively, and 725 large breaches of protected health information were reported in the United States that year. Such incidents increasingly disrupt IR workflows, delay emergent and elective procedures, force patient diversion, and create downstream clinical risks. This review synthesizes data from national reports, peer-reviewed literature, and real-world case examples to highlight high-priority threats including ransomware, credential compromise, vendor and supply chain exposures, insecure Internet of Medical Things devices, and vulnerabilities associated with artificial intelligence tools and aligns them with practical mitigation strategies grounded in the National Institute of Standards and Technology Cybersecurity Framework. By engaging directly in cybersecurity governance, risk assessment, and downtime planning, IR physicians can help ensure resilient imaging infrastructure and safe adoption of emerging technologies, safeguarding patient care when it matters most.
{"title":"Cybersecurity for Interventional Radiologists: A Clinical Imperative for Protecting Patient Data and Imaging Systems","authors":"Didier Jourdain BS","doi":"10.1016/j.jvir.2025.107920","DOIUrl":"10.1016/j.jvir.2025.107920","url":null,"abstract":"<div><div>Cybersecurity threats to medical imaging systems and workflows are no longer confined to information technology departments; they directly affect interventional radiology (IR) practice, patient safety, and procedural continuity. Two thirds of healthcare organizations experienced ransomware in 2024, with median and mean ransom payments of 1.5 million and 4.4 million dollars, respectively, and 725 large breaches of protected health information were reported in the United States that year. Such incidents increasingly disrupt IR workflows, delay emergent and elective procedures, force patient diversion, and create downstream clinical risks. This review synthesizes data from national reports, peer-reviewed literature, and real-world case examples to highlight high-priority threats including ransomware, credential compromise, vendor and supply chain exposures, insecure Internet of Medical Things devices, and vulnerabilities associated with artificial intelligence tools and aligns them with practical mitigation strategies grounded in the National Institute of Standards and Technology Cybersecurity Framework. By engaging directly in cybersecurity governance, risk assessment, and downtime planning, IR physicians can help ensure resilient imaging infrastructure and safe adoption of emerging technologies, safeguarding patient care when it matters most.</div></div>","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":"37 3","pages":"Article 107920"},"PeriodicalIF":2.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145574827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
To assess whether patient factors, including age, sex, and diabetic involvement, are associated with adverse events during the course of tunneled peritoneal dialysis (PD) catheter placed by interventional radiology (IR).
Materials and Methods
This retrospective cohort study examined patients (n = 104) who required kidney replacement and underwent their initial tunneled PD catheter insertion procedure by the IR team at an academic teaching hospital between July 2021 and May 2024. An adverse event during the course of PD was defined as the first episode of peritonitis, catheter dysfunction, catheter insufficiency, catheter intolerance, or death. Inferential analyses included logistic regression and Cox proportional-hazards models to assess potential risk factors.
Results
Of the included patients, 32 (30.8%) experienced at least 1 episode of peritonitis during their PD course, with 6 patients experiencing multiple episodes. Diabetic involvement had the highest hazard ratio of 1.59 (95% confidence interval, 0.92–2.75; P = .094), suggesting a potential association with the occurrence of adverse events. Staphylococcus infections appeared to be more common in late-onset peritonitis (P = .03).
Conclusions
Peritonitis remains a major adverse event of PD despite current best practices. Moreover, the differences in the causative organism based on the time of episode warrant further attention, especially in terms of its management and empiric antibiotics. Diabetic involvement also remains a significant risk for the occurrence of an adverse event in the course of the inserted catheter. A deeper understanding of the complexities associated with PD is essential to achieving better clinical outcomes.
目的:评估患者因素,包括年龄、性别和糖尿病患者是否与介入放射学放置隧道腹膜透析(PD)导管过程中的不良事件相关。材料和方法:本回顾性队列研究调查了2021年7月至2024年5月期间在一家学术教学医院的介入放射学团队进行的需要肾脏置换并首次行隧道PD导管置入手术的患者(n=104)。PD过程中的不良事件定义为首次腹膜炎、导管功能障碍、导管不全、导管不耐受或死亡。推断分析包括逻辑回归和Cox比例风险模型来评估潜在的危险因素。结果:在纳入的患者中,32例(30.8%)在PD病程中至少经历一次腹膜炎发作,其中6例经历多次发作。糖尿病患者的风险比最高,为1.59,CI 0.92-2.75, p =0.094,提示与不良事件的发生存在潜在关联。葡萄球菌感染在迟发性腹膜炎(LOP)中更为常见(p =0.03)。结论:腹膜炎仍然是腹膜透析的主要并发症,尽管目前的最佳做法。此外,基于发病时间的致病生物的差异值得进一步关注,特别是在其管理和经验性抗生素方面。糖尿病患者在导管插入过程中发生不良事件的风险也很大。更深入地了解PD的复杂性对于获得更好的临床结果至关重要。
{"title":"Outcomes and Risk Factors Following Tunneled Peritoneal Dialysis Catheter Insertion by Interventional Radiologists","authors":"Rithvik Karthikeyan MB, BCh, BAO , Ileesha Singh BS , Satvik Hadigal MD , Daniel Picus MD , Naganathan Mani MD","doi":"10.1016/j.jvir.2025.09.031","DOIUrl":"10.1016/j.jvir.2025.09.031","url":null,"abstract":"<div><h3>Purpose</h3><div>To assess whether patient factors, including age, sex, and diabetic involvement, are associated with adverse events during the course of tunneled peritoneal dialysis (PD) catheter placed by interventional radiology (IR).</div></div><div><h3>Materials and Methods</h3><div>This retrospective cohort study examined patients (n = 104) who required kidney replacement and underwent their initial tunneled PD catheter insertion procedure by the IR team at an academic teaching hospital between July 2021 and May 2024. An adverse event during the course of PD was defined as the first episode of peritonitis, catheter dysfunction, catheter insufficiency, catheter intolerance, or death. Inferential analyses included logistic regression and Cox proportional-hazards models to assess potential risk factors.</div></div><div><h3>Results</h3><div>Of the included patients, 32 (30.8%) experienced at least 1 episode of peritonitis during their PD course, with 6 patients experiencing multiple episodes. Diabetic involvement had the highest hazard ratio of 1.59 (95% confidence interval, 0.92–2.75; <em>P</em> = .094), suggesting a potential association with the occurrence of adverse events. Staphylococcus infections appeared to be more common in late-onset peritonitis (<em>P</em> = .03).</div></div><div><h3>Conclusions</h3><div>Peritonitis remains a major adverse event of PD despite current best practices. Moreover, the differences in the causative organism based on the time of episode warrant further attention, especially in terms of its management and empiric antibiotics. Diabetic involvement also remains a significant risk for the occurrence of an adverse event in the course of the inserted catheter. A deeper understanding of the complexities associated with PD is essential to achieving better clinical outcomes.</div></div>","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":"37 3","pages":"Article 107860"},"PeriodicalIF":2.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145187358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-01Epub Date: 2025-09-26DOI: 10.1016/j.jvir.2025.09.032
Austin J. Triana MD, MBA , Brian P. Triana MD, MBA , Charles Y. Kim MD , James Ronald MD, PhD
Purpose
To identify patient factors influencing the time-dependent response of ascites and hydrothorax after transjugular intrahepatic portosystemic shunt (TIPS) creation using a large claims data set.
Materials and Methods
Adult patients from a nationwide claims database with at least 4 paracenteses or thoracenteses within 60 days before TIPS and at least 30 days follow-up were included (paracentesis cohort, n = 3,742; diuretic subset, n = 1,110; thoracentesis cohort, n = 238). Continuous-time hidden Markov models were used to classify patients into underlying response states—nonresponse, partial response, and complete response (CR)—based on observed paracentesis, diuretic prescription, and thoracentesis claims. Transition intensities between response states were used to quantify how quickly patients responded to TIPS. Covariate effects influencing response time were estimated.
Results
In the paracentesis cohort, CR probabilities were 48%, 70%, and 88% at 90, 180, and 365 days post-TIPS, respectively. Male sex, metabolic dysfunction–associated steatohepatitis cirrhosis, and higher pre-TIPS paracentesis rates predicted slower freedom from paracenteses, whereas alcoholic cirrhosis predicted faster response. Among diuretic users, 38% achieved freedom from diuretics at 1 year; younger age and lower pre-TIPS dose predicted faster weaning. In the hydrothorax cohort, CR rates at 90, 180, and 365 days were 54%, 81%, and 94%. Higher pre-TIPS thoracentesis rates predicted slower response.
Conclusions
Although 88%–94% of patients no longer required paracenteses and thoracenteses within a year after TIPS creation, only half achieved CR by 90 days. The potentially protracted time course may help physicians to better counsel patients regarding expected outcomes after TIPS creation.
{"title":"Predictors of Time-Dependent Ascites and Hydrothorax Response after Transjugular Intrahepatic Portosystemic Shunt Creation: A Claims Analysis","authors":"Austin J. Triana MD, MBA , Brian P. Triana MD, MBA , Charles Y. Kim MD , James Ronald MD, PhD","doi":"10.1016/j.jvir.2025.09.032","DOIUrl":"10.1016/j.jvir.2025.09.032","url":null,"abstract":"<div><h3>Purpose</h3><div>To identify patient factors influencing the time-dependent response of ascites and hydrothorax after transjugular intrahepatic portosystemic shunt (TIPS) creation using a large claims data set.</div></div><div><h3>Materials and Methods</h3><div>Adult patients from a nationwide claims database with at least 4 paracenteses or thoracenteses within 60 days before TIPS and at least 30 days follow-up were included (paracentesis cohort, n = 3,742; diuretic subset, n = 1,110; thoracentesis cohort, n = 238). Continuous-time hidden Markov models were used to classify patients into underlying response states—nonresponse, partial response, and complete response (CR)—based on observed paracentesis, diuretic prescription, and thoracentesis claims. Transition intensities between response states were used to quantify how quickly patients responded to TIPS. Covariate effects influencing response time were estimated.</div></div><div><h3>Results</h3><div>In the paracentesis cohort, CR probabilities were 48%, 70%, and 88% at 90, 180, and 365 days post-TIPS, respectively. Male sex, metabolic dysfunction–associated steatohepatitis cirrhosis, and higher pre-TIPS paracentesis rates predicted slower freedom from paracenteses, whereas alcoholic cirrhosis predicted faster response. Among diuretic users, 38% achieved freedom from diuretics at 1 year; younger age and lower pre-TIPS dose predicted faster weaning. In the hydrothorax cohort, CR rates at 90, 180, and 365 days were 54%, 81%, and 94%. Higher pre-TIPS thoracentesis rates predicted slower response.</div></div><div><h3>Conclusions</h3><div>Although 88%–94% of patients no longer required paracenteses and thoracenteses within a year after TIPS creation, only half achieved CR by 90 days. The potentially protracted time course may help physicians to better counsel patients regarding expected outcomes after TIPS creation.</div></div>","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":"37 3","pages":"Article 107861"},"PeriodicalIF":2.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145187328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-03-01Epub Date: 2025-09-18DOI: 10.1016/j.jvir.2025.08.046
Sameer Bhatia MBBS, MS
{"title":"Histopathologic Response and Oncologic Outcomes after Transarterial Chemoembolization and Transarterial Radioembolization for Hepatocellular Carcinoma: Selection Bias and Suboptimal Technique Are Better Explanations","authors":"Sameer Bhatia MBBS, MS","doi":"10.1016/j.jvir.2025.08.046","DOIUrl":"10.1016/j.jvir.2025.08.046","url":null,"abstract":"","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":"37 3","pages":"Article 107851"},"PeriodicalIF":2.6,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145102844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}