This study investigated the effects of yttrium-90 (90Y) radioembolization in 8 rabbits, focusing on delivery accuracy, dosimetry, and pathological outcomes. 90Y was successfully delivered angiographically targeted via the pulmonary lower basal segmental arteries to all rabbits, with confirmation via positron emission tomography (PET)/computed tomography (CT) imaging and a lung target median of the mean dose of 132.1 Gy (range, 11.2–262.3 Gy). Pathological analysis in all surviving subjects revealed complete necrosis of the irradiated segments, with associated inflammation in adjacent nonirradiated tissue. Radiological follow-up with CT scan showed triangular fibrosis in 6 rabbits at 1 month, progressing to fibrosis at 3 months. Dosimetry analysis confirmed dose distribution to the targeted lung regions. Of 8 rabbits, 1 died intraprocedurally, and another died 1.5 weeks after the procedure for unknown reasons. The remaining rabbits had no severe adverse events, with 1 case of pleural effusion resolving with no intervention at 3 months. The study demonstrated the feasibility of 90Y delivery to the lungs.
{"title":"Feasibility and Effectiveness of Yttrium-90 Radioembolization in Normal Lung Parenchyma: A Preclinical Study in Rabbits with Pathological Correlation to Absorbed Dose","authors":"Ioannis Spyridonidis MD , Marios Platon Dimopoulos MD, MSc, PhD(c) , Pinelopi Bosgana MD , Trifon Spyridonidis MD , Theodoros Skouras MD , Michalis Theofanis MD , Christos Papageorgiou MD , Nikolaos Giannikas MD, MSc , Panagiotis M. Kitrou MD, MSc, PhD , Konstantinos Katsanos MD, MSc, PhD , Dimitrios Karnabatidis MD, PhD","doi":"10.1016/j.jvir.2025.08.044","DOIUrl":"10.1016/j.jvir.2025.08.044","url":null,"abstract":"<div><div>This study investigated the effects of yttrium-90 (<sup>90</sup>Y) radioembolization in 8 rabbits, focusing on delivery accuracy, dosimetry, and pathological outcomes. <sup>90</sup>Y was successfully delivered angiographically targeted via the pulmonary lower basal segmental arteries to all rabbits, with confirmation via positron emission tomography (PET)/computed tomography (CT) imaging and a lung target median of the mean dose of 132.1 Gy (range, 11.2–262.3 Gy). Pathological analysis in all surviving subjects revealed complete necrosis of the irradiated segments, with associated inflammation in adjacent nonirradiated tissue. Radiological follow-up with CT scan showed triangular fibrosis in 6 rabbits at 1 month, progressing to fibrosis at 3 months. Dosimetry analysis confirmed dose distribution to the targeted lung regions. Of 8 rabbits, 1 died intraprocedurally, and another died 1.5 weeks after the procedure for unknown reasons. The remaining rabbits had no severe adverse events, with 1 case of pleural effusion resolving with no intervention at 3 months. The study demonstrated the feasibility of <sup>90</sup>Y delivery to the lungs.</div></div>","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":"37 1","pages":"Article 107827"},"PeriodicalIF":2.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145008578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01DOI: 10.1016/S1051-0443(25)00789-4
{"title":"Subscription Information","authors":"","doi":"10.1016/S1051-0443(25)00789-4","DOIUrl":"10.1016/S1051-0443(25)00789-4","url":null,"abstract":"","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":"37 1","pages":"Article 107949"},"PeriodicalIF":2.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145883325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01DOI: 10.1016/j.jvir.2025.09.035
Sonam Santdasani APRN, FNP-BC , Jesse Liu MD , Scott Rewinkel MD , Marco Colasurdo MD
{"title":"Balloon-Guided Aspiration Thrombectomy of Internal Carotid Artery following Penetrating and Blunt Injury through the Skull Base","authors":"Sonam Santdasani APRN, FNP-BC , Jesse Liu MD , Scott Rewinkel MD , Marco Colasurdo MD","doi":"10.1016/j.jvir.2025.09.035","DOIUrl":"10.1016/j.jvir.2025.09.035","url":null,"abstract":"","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":"37 1","pages":"Article 107864"},"PeriodicalIF":2.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145883419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01DOI: 10.1016/j.jvir.2025.08.015
Mathias Montveneur MD , Guillaume Daniel MD , Pierre-Jules Delannoy MD , Kinga Michalewska MD , Sonia Ramos-Pascual MEng, PhD , Mo Saffarini MEng, MBA , Nicolas Bouchareine MD
Purpose
To compare the outcomes of atherectomy versus stent placement for common femoral artery (CFA) symptomatic atherosclerosis.
Materials and Methods
This review followed Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and was registered in PROSPERO. MEDLINE and Embase databases were searched for records from 2000 to 2023. The following data were extracted and tabulated: (a) characteristics of studies, (b) patients, (c) lesions and interventions, and (d) clinical and technical outcomes. Risk of bias was assessed using Mixed Methods Appraisal Tool (MMAT).
Results
The search identified 2,088 references, of which 33 studies were included: 11 reported only on atherectomy, 20 reported only on stent placement, and 2 reported on both treatments. Atherectomy and stent placement studies were comparable in terms of age, sex, prevalence of comorbidities, chronic limb ischemia, preprocedural Rutherford score, and ankle-brachial index. Technical success ranged across the studies from 92% to 100% for atherectomy versus 94% to 100% for stent placement, periprocedural adverse event rates ranged from 0% to 24% versus 0% to 19%, rates of freedom from target lesion revascularization ranged from 83% to 100% versus 81% to 100%, and limb salvage rates ranged from 85% to 100% versus 94% to 100%. Stent fracture rates ranged from 0% to 8%. Only 5 of 13 studies on atherectomy and 5 of 22 studies on stent placement met all 7 MMAT criteria.
Conclusions
This systematic review demonstrates satisfactory outcomes with both methods, with no clear advantage of one technique over the other. However, available data on these 2 techniques are heterogeneous. Future studies are necessary to conclude if either technique is superior for the treatment of symptomatic CFA atherosclerosis.
{"title":"Atherectomy versus Stent Placement for Common Femoral Artery Atherosclerotic Disease: A Systematic Review","authors":"Mathias Montveneur MD , Guillaume Daniel MD , Pierre-Jules Delannoy MD , Kinga Michalewska MD , Sonia Ramos-Pascual MEng, PhD , Mo Saffarini MEng, MBA , Nicolas Bouchareine MD","doi":"10.1016/j.jvir.2025.08.015","DOIUrl":"10.1016/j.jvir.2025.08.015","url":null,"abstract":"<div><h3>Purpose</h3><div>To compare the outcomes of atherectomy versus stent placement for common femoral artery (CFA) symptomatic atherosclerosis.</div></div><div><h3>Materials and Methods</h3><div>This review followed Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and was registered in PROSPERO. MEDLINE and Embase databases were searched for records from 2000 to 2023. The following data were extracted and tabulated: (<em>a</em>) characteristics of studies, (<em>b</em>) patients, (<em>c</em>) lesions and interventions, and (<em>d</em>) clinical and technical outcomes. Risk of bias was assessed using Mixed Methods Appraisal Tool (MMAT).</div></div><div><h3>Results</h3><div>The search identified 2,088 references, of which 33 studies were included: 11 reported only on atherectomy, 20 reported only on stent placement, and 2 reported on both treatments. Atherectomy and stent placement studies were comparable in terms of age, sex, prevalence of comorbidities, chronic limb ischemia, preprocedural Rutherford score, and ankle-brachial index. Technical success ranged across the studies from 92% to 100% for atherectomy versus 94% to 100% for stent placement, periprocedural adverse event rates ranged from 0% to 24% versus 0% to 19%, rates of freedom from target lesion revascularization ranged from 83% to 100% versus 81% to 100%, and limb salvage rates ranged from 85% to 100% versus 94% to 100%. Stent fracture rates ranged from 0% to 8%. Only 5 of 13 studies on atherectomy and 5 of 22 studies on stent placement met all 7 MMAT criteria.</div></div><div><h3>Conclusions</h3><div>This systematic review demonstrates satisfactory outcomes with both methods, with no clear advantage of one technique over the other. However, available data on these 2 techniques are heterogeneous. Future studies are necessary to conclude if either technique is superior for the treatment of symptomatic CFA atherosclerosis.</div></div>","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":"37 1","pages":"Article 107798"},"PeriodicalIF":2.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144976705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
To determine if use of mechanical thrombectomy (MT) impacts survival and additional outcomes in patients with acute intermediate-high–risk and high-risk pulmonary embolism (PE) who were evaluated by a Pulmonary Embolism Response Team (PERT).
Methods
This retrospective, single-center study included patients with intermediate-high–risk and high-risk PE who received PERT evaluation over 3.5 years and were treated with anticoagulation (AC) alone or MT + AC. The primary outcome was 30-day all-cause mortality, measured with inverse probability of treatment weighting. Exploratory outcomes included survival during the study period, PE-associated/caused mortality, hospital length of stay (LOS), supplemental oxygen at discharge, and MT-related metrics.
Results
Of 335 patients, 259 received AC alone and 76 received MT + AC. The use of MT was associated with reduced odds of 30-day all-cause mortality (odds ratio, 0.49; 95% CI, 0.27–0.76; P = .002). There were no significant differences in PE-associated/caused mortality. Hospital LOS was 2 days shorter in the MT + AC cohort (P < .001). Of patients receiving MT + AC, those with high-risk PE had a 4.5-day shorter stay (P < .001), whereas those with intermediate-high–risk PE had a 2-day shorter stay (P < .001). The proportion of patients receiving supplemental oxygen at discharge was lower in the MT + AC group (MT + AC vs AC, 4.1% vs 18.5%; P < .001), without significant differences in 30-day readmission rates (MT + AC vs AC, 9.5% vs 20.6%; P = .115). MT resulted in an 8.7-mm Hg reduction in mean pulmonary artery pressure, had a technical success rate of 100% (76 of 76), and an adverse event rate of 6.6% (5 of 76).
Conclusions
MT reduced 30-day all-cause mortality, hospital LOS, and supplemental oxygen at discharge in the intermediate-high–risk and high-risk PE population.
{"title":"Clinical Outcomes following Mechanical Thrombectomy in Pulmonary Embolism Response Team–Consulted Patients: A Retrospective Analysis","authors":"Ryan Nolan BS , Maanasi Samant MD , Suresh Vedantham MD , Westley Ohman MD , Nathan Droz MD , Kristen Sanfilippo MD, MPHS , Pavan Kavali MD","doi":"10.1016/j.jvir.2025.09.008","DOIUrl":"10.1016/j.jvir.2025.09.008","url":null,"abstract":"<div><h3>Purpose</h3><div>To determine if use of mechanical thrombectomy (MT) impacts survival and additional outcomes in patients with acute intermediate-high–risk and high-risk pulmonary embolism (PE) who were evaluated by a Pulmonary Embolism Response Team (PERT).</div></div><div><h3>Methods</h3><div>This retrospective, single-center study included patients with intermediate-high–risk and high-risk PE who received PERT evaluation over 3.5 years and were treated with anticoagulation (AC) alone or MT + AC. The primary outcome was 30-day all-cause mortality, measured with inverse probability of treatment weighting. Exploratory outcomes included survival during the study period, PE-associated/caused mortality, hospital length of stay (LOS), supplemental oxygen at discharge, and MT-related metrics.</div></div><div><h3>Results</h3><div>Of 335 patients, 259 received AC alone and 76 received MT + AC. The use of MT was associated with reduced odds of 30-day all-cause mortality (odds ratio, 0.49; 95% CI, 0.27–0.76; <em>P</em> = .002). There were no significant differences in PE-associated/caused mortality. Hospital LOS was 2 days shorter in the MT + AC cohort (<em>P</em> < .001). Of patients receiving MT + AC, those with high-risk PE had a 4.5-day shorter stay (<em>P</em> < .001), whereas those with intermediate-high–risk PE had a 2-day shorter stay (<em>P</em> < .001). The proportion of patients receiving supplemental oxygen at discharge was lower in the MT + AC group (MT + AC vs AC, 4.1% vs 18.5%; <em>P</em> < .001), without significant differences in 30-day readmission rates (MT + AC vs AC, 9.5% vs 20.6%; <em>P</em> = .115). MT resulted in an 8.7-mm Hg reduction in mean pulmonary artery pressure, had a technical success rate of 100% (76 of 76), and an adverse event rate of 6.6% (5 of 76).</div></div><div><h3>Conclusions</h3><div>MT reduced 30-day all-cause mortality, hospital LOS, and supplemental oxygen at discharge in the intermediate-high–risk and high-risk PE population.</div></div>","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":"37 1","pages":"Article 107836"},"PeriodicalIF":2.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145058735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01DOI: 10.1016/j.jvir.2025.09.016
Aren B. Mnatzakanian MD , Bronwyn L. Schemmer BHSc , Neil J. Resnick MD , Karim Virani MD, MSc
{"title":"Lessons in IR: Management of Radial Artery Pseudoaneurysm with Extended Hemostatic Band Compression","authors":"Aren B. Mnatzakanian MD , Bronwyn L. Schemmer BHSc , Neil J. Resnick MD , Karim Virani MD, MSc","doi":"10.1016/j.jvir.2025.09.016","DOIUrl":"10.1016/j.jvir.2025.09.016","url":null,"abstract":"","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":"37 1","pages":"Article 107844"},"PeriodicalIF":2.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145883423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-01DOI: 10.1016/j.jvir.2025.08.042
Edward J. Walsh MD , Hasnain Bawaadam MD, MPH , Joseph G. Mammarappallil MD, PhD , Jason R. Snider MD , William C. Allsopp DO , Frederick J. Brodeur MD , Aaron R. Green MD , Ganesh Krishna MD , Brandon M. Wojcik MD
Thoracic surgeons using minimally invasive techniques for lung nodule resection often rely on localization markers to determine precise nodule location intraoperatively. Transbronchial or transthoracic injection of indocyanine green (ICG) dye has become a popular technique. However, surgery must be performed immediately before dye dissipates into surrounding tissue. This multicenter retrospective study evaluated the effectiveness of computed tomography (CT)–guided transthoracic placement of ICG dye–soaked coils (ICG-Cs) for preoperative lung nodule localization. Nineteen adult patients with 21 nodules underwent CT ICG-C placement from March 01, 2023, until February 28, 2025, at 2 medical centers. There were no adverse events. Median time from localization to surgery was 1 day (interquartile range, 0–4 days), with 57.1% undergoing surgery >24 hours later. Localization success rate was 100%. CT-guided transthoracic placement of ICG-C is a novel technique that allows for accurate nodule localization, delayed surgical resection, and the preservation of healthy lung tissue.
{"title":"Lung Tumors Marked Percutaneously with Indocyanine Green Dye–Soaked Embolization Coils: A Visual Beacon for Accurate Intraoperative Localization during Lung-Sparing Surgery","authors":"Edward J. Walsh MD , Hasnain Bawaadam MD, MPH , Joseph G. Mammarappallil MD, PhD , Jason R. Snider MD , William C. Allsopp DO , Frederick J. Brodeur MD , Aaron R. Green MD , Ganesh Krishna MD , Brandon M. Wojcik MD","doi":"10.1016/j.jvir.2025.08.042","DOIUrl":"10.1016/j.jvir.2025.08.042","url":null,"abstract":"<div><div>Thoracic surgeons using minimally invasive techniques for lung nodule resection often rely on localization markers to determine precise nodule location intraoperatively. Transbronchial or transthoracic injection of indocyanine green (ICG) dye has become a popular technique. However, surgery must be performed immediately before dye dissipates into surrounding tissue. This multicenter retrospective study evaluated the effectiveness of computed tomography (CT)–guided transthoracic placement of ICG dye–soaked coils (ICG-Cs) for preoperative lung nodule localization. Nineteen adult patients with 21 nodules underwent CT ICG-C placement from March 01, 2023, until February 28, 2025, at 2 medical centers. There were no adverse events. Median time from localization to surgery was 1 day (interquartile range, 0–4 days), with 57.1% undergoing surgery >24 hours later. Localization success rate was 100%. CT-guided transthoracic placement of ICG-C is a novel technique that allows for accurate nodule localization, delayed surgical resection, and the preservation of healthy lung tissue.</div></div>","PeriodicalId":49962,"journal":{"name":"Journal of Vascular and Interventional Radiology","volume":"37 1","pages":"Article 107825"},"PeriodicalIF":2.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145008507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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