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Lung Cancer Screening by Nativity Among Latino Community Health Center Patients. 拉丁裔社区健康中心患者的出生肺癌筛查
IF 2.6 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-09-15 DOI: 10.3122/jabfm.2024.240376R1
John Heintzman, Tahlia Hodes, Steffani R Bailey, Christopher G Slatore, Wyatt P Bensken, Jennifer A Lucas, Matthew P Banegas, Gretchen Mertes, Miguel Marino

Introduction: United States Preventive Service Task Force guidelines recommend annual low-dose computed tomography for lung cancer screening (LCS) for people with significant history of cigarette use. While the national prevalence of lung cancer screening remains low, with known racial and ethnic disparities, studies have yet to examine LCS screening disparities by nativity among Latino patients.

Methods: We evaluated the documentation and prevalence of LCS orders in the electronic health record in Latino patients, by place of birth, in a multistate network of community health centers, over a 10-year study period (2013 to 2022), adjusting for patient and clinical demographic factors.

Results: Among patients who reported current or former cigarette use (n = 126,528), the prevalence of a LCS order was 7.3%. Among 62,483 patients with a documented 30+ year pack-history, US-born Latinos had equal odds as non-Latino Whites to have LCS ordered (OR = 0.71, 95% CI = 0.42-1.21), while odds were lower for both foreign-born Latinos (OR = 0.47, 95% CI = 0.29 to 0.75) and Latinos without a place of birth recorded (OR = 0.63, 95% CI = 0.54-0.73).

Conclusion: The prevalence of LCS was low overall in a large sample of Latino and non-Hispanic White patients with cigarette smoking history. Foreign-born Latino and Latino patients without a country of birth noted in the record had significantly lower odds of having LCS ordered; this should be considered in clinical screening workflows. Nativity and pack-year history were not documented in most patients. More complete documentation of nativity and pack-year history is necessary to fully assess LCS need and equity in Latino patients of heterogeneous nativity.

简介:美国预防服务工作组指南建议每年对有明显吸烟史的人进行低剂量ct肺癌筛查(LCS)。虽然全国肺癌筛查的流行率仍然很低,并且存在已知的种族和民族差异,但研究尚未检查拉丁裔患者中出生的LCS筛查差异。方法:在10年的研究期间(2013年至2022年),我们在多州社区卫生中心网络中评估拉丁裔患者电子健康记录中LCS订单的记录和流行程度,并根据患者和临床人口统计学因素进行调整。结果:在报告当前或曾经吸烟的患者中(n = 126528), LCS订单的患病率为7.3%。在62,483例有30年以上病史的患者中,美国出生的拉丁裔与非拉丁裔白人有相同的几率进行LCS (OR = 0.71, 95% CI = 0.42-1.21),而外国出生的拉丁裔(OR = 0.47, 95% CI = 0.29 - 0.75)和没有出生记录的拉丁裔(OR = 0.63, 95% CI = 0.54-0.73)的几率较低。结论:在大量有吸烟史的拉美裔和非拉美裔白人患者中,LCS的总体患病率较低。外国出生的拉丁裔和没有出生国家记录的拉丁裔患者订购LCS的几率显着降低;在临床筛查工作流程中应考虑到这一点。大多数患者无出生年月史。更完整的出生和包年历史的文件是必要的,以充分评估LCS的需求和公平的拉丁裔患者的异质出生。
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引用次数: 0
Balancing Access, Well-Being, and Collaboration When Considering Hybrid Care Delivery Models in Primary Care Practices with Team-Based Care. 当考虑初级保健实践与团队护理的混合护理交付模式时,平衡获取、福祉和协作。
IF 2.6 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-09-15 DOI: 10.3122/jabfm.2024.240388R2
Tamar Wyte-Lake, Deborah J Cohen, Shannon Williams, Steffani R Bailey

Background: Hybrid models of care (ie, telehealth and in-person care delivery options) have been incorporated into primary care clinics to increase patient access to care. We examine the effects of these approaches on the work experiences and wellness of primary care clinical team members providing team-based care to patients.

Methods: In this qualitative study, we conducted semistructured interviews with clinical team members (primary care clinicians, behavioral health consultants, registered nurse) at 2 primary care practices at 2 time points (late 2021-mid 2022 (n = 14); midlate 2023 (n = 11)). We used an inductive approach to analyze data.

Key results: Benefits of hybrid models of care included increased patient access and personal flexibility; however, it was noted that the fragmented in-clinic schedules that emerged from the hybrid model resulted in reduced in-clinic interactions. This led to less information sharing among team members and a degradation of informal support networks that could adversely impact patient care. To mitigate these challenges, many preferred that most of their clinical shifts occurred in-person, in the clinic, with 1 to 2 sessions per week for in-home (telework) shifts.

Conclusions: In team-based primary care clinics, hybrid care models can impact interactions among clinical team members and shape the day-to-day environment in which clinical teams work. To optimize hybrid care approaches in the primary care setting, organization leaders must consider the impact of hybrid care models on clinic and team culture, and the well-being of clinical team members.

背景:混合护理模式(即远程保健和亲自提供护理选择)已被纳入初级保健诊所,以增加患者获得护理的机会。我们研究了这些方法对初级保健临床团队成员的工作经验和健康的影响,为患者提供团队护理。方法:在本定性研究中,我们在2个时间点(2021年末- 2022年中(n = 14);2023年中期(n = 11))。我们用归纳的方法来分析数据。主要结果:混合护理模式的好处包括增加患者访问和个人灵活性;然而,值得注意的是,从混合模式中出现的分散的门诊时间表导致了门诊互动的减少。这导致团队成员之间的信息共享减少,非正式支持网络的退化可能对患者护理产生不利影响。为了减轻这些挑战,许多人倾向于他们的大部分临床轮班都是在诊所进行的,每周有1到2次的在家(远程工作)轮班。结论:在基于团队的初级保健诊所中,混合护理模式可以影响临床团队成员之间的互动,并塑造临床团队工作的日常环境。为了在初级保健环境中优化混合护理方法,组织领导者必须考虑混合护理模式对临床和团队文化的影响,以及临床团队成员的福祉。
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引用次数: 0
Pitavastatin Reduces Major Atherosclerotic Cardiovascular Events in Adults with HIV. 匹伐他汀可降低成人HIV患者的主要动脉粥样硬化性心血管事件。
IF 2.6 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-09-15 DOI: 10.3122/jabfm.2025.250014R0
Kathryn K Garner, Chris Colvin, Brock Cardon

Initiation of pitavastatin in adults aged 40 to 75 living with HIV treated with highly active antiretroviral therapy (HAART) with low-to-moderate 10-year atherosclerotic cardiovascular disease (ASCVD) risk decreases the incidence of major cardiovascular events (MACE).

在接受高效抗逆转录病毒治疗(HAART)且10年低至中度动脉粥样硬化性心血管疾病(ASCVD)风险的40 - 75岁艾滋病毒感染者中,开始使用匹伐他汀可降低主要心血管事件(MACE)的发生率。
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引用次数: 0
Reducing Anticoagulation Duration for Children After a Provoked Deep Venous Thrombosis. 减少儿童诱发性深静脉血栓形成后抗凝时间。
IF 2.6 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-09-15 DOI: 10.3122/jabfm.2025.250001R0
Benjamin Feijóo, Roxanne Radi, Corey Lyon

In patients younger than 21 years of age with a provoked deep venous thrombosis (DVT), anticoagulation for 6 weeks is noninferior to anticoagulation for 3 months.1.

对于年龄小于21岁的深静脉血栓(DVT)患者,6周抗凝治疗优于3个月抗凝治疗。
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引用次数: 0
Understanding the Barriers and Facilitators of Implementing a Controlled Substance Safety Committee in a Primary Care Practice. 了解在初级保健实践中实施受控物质安全委员会的障碍和促进因素。
IF 2.6 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-09-15 DOI: 10.3122/jabfm.2024.240220R3
Mechelle Sanders, Anna Russell, Kaela Mali, Jenny Ganay Vasquez, Sean Chambers, Holly Ann Russell

Purpose: The few studies about primary care based controlled substance safety committees (CSSC) to date have been primarily quantitative, focused on patient outcomes and lacked contextual data around their implementation. The purpose of this study is to qualitatively identify barriers and facilitators to the use of CDCs guidelines around opioid prescribing and the implementation of controlled substance safety committee in a primary care practice.

Methods: Ten semistructured interviews were conducted with primary care clinicians in an academic medical practice. Potential barriers and facilitators to the uptake and use of the CDC opioid guidelines and the practice's CSSC were coded and analyzed against the Capability, Opportunity, and Motivation framework for Behavior change framework (COM-B).

Results: Six key themes were identified around uptake of the CDC guidelines. In general, the CSSC addressed some of the capability barriers around the guidelines but had limited impact on increasing motivation to follow the guidelines. We found the same recommendation in the guidelines could have differing impact on prescribing behavior.

Conclusions: Simply promoting guidelines may be insufficient, especially for those viewing them as rules rather than recommendations. Our findings underscore the fact that guidelines are merely a starting point, not an endpoint of implementation.

目的:迄今为止,关于基于初级保健的受控物质安全委员会(CSSC)的少数研究主要是定量的,关注患者的结果,缺乏有关其实施的背景数据。本研究的目的是定性地确定在初级保健实践中使用cdc阿片类药物处方指南和实施受控物质安全委员会的障碍和促进因素。方法:采用半结构化访谈法对某学术医疗实践中的初级保健临床医生进行访谈。根据行为改变框架(COM-B)的能力、机会和动机框架,对吸收和使用CDC阿片类药物指南和实践CSSC的潜在障碍和促进因素进行了编码和分析。结果:围绕CDC指南的采用确定了六个关键主题。总的来说,CSSC解决了围绕指南的一些能力障碍,但对增加遵循指南的动机的影响有限。我们发现,指南中同样的建议可能对处方行为产生不同的影响。结论:简单地推广指南可能是不够的,特别是对于那些将其视为规则而非建议的人。我们的发现强调了这样一个事实:指导方针仅仅是一个起点,而不是实施的终点。
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引用次数: 0
Prenatal Care Coordination and Well-Child Visit Receipt in Early Childhood. 幼儿期产前护理协调与访视收据。
IF 2.6 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-09-15 DOI: 10.3122/jabfm.2024.240302R2
David C Mallinson

Introduction: This study evaluates participation in Wisconsin Medicaid's Prenatal Care Coordination (PNCC) program and its association with children's well-child visit (WCV) receipt.

Study design: Data came from linked Wisconsin birth records (2011 to 2015) and Medicaid claims and enrollment data (2010 to 2019). The sample comprised 113,347 children with Medicaid-paid births and continuous Medicaid enrollment ranging from 12 to 48 months post-birth. A sibling subsample comprised of 35,373 children. PNCC receipt in pregnancy was measured dichotomously (none; any) and categorically (none; assessment/care plan only; service uptake). Any WCV receipt and recommended WCV receipt (which varied by age) were measured during each year from age 0 up to 4 years old. Conventional logistic regressions and sibling fixed effects (FE) regressions estimated associations between PNCC receipt and WCV receipt.

Results: Demographic-adjusted sibling FE regressions-which best control for unobserved confounding-indicated that any PNCC was positively associated with children receiving any WCVs at age 0 to <1 year-old (OR 1.48; 95% CI 1.05-2.08) and at age 1 to <2 years old (OR 1.24; 95% CI 1.03-1.50). In addition, adjusted sibling FE regressions found that PNCC service uptake was associated with children receiving the recommended number of WCVs at age 0 to <1 year-old (OR 1.35; 95% CI 1.18-1.55).

Conclusions: PNCC may improve children's WCV attendance in the first 2 years of life. Findings underscore the potential for obstetric care coordination programs to enhance the continuity of preventive care for participating families.

简介:本研究评估了威斯康星州医疗补助产前护理协调(PNCC)计划的参与情况及其与儿童健康访问(WCV)收据的关系。研究设计:数据来自威斯康星州的出生记录(2011年至2015年)和医疗补助申请和入学数据(2010年至2019年)。样本包括113,347名在出生后12至48个月期间享受医疗补助的儿童。一个由35373名儿童组成的兄弟姐妹子样本。妊娠期PNCC接收量采用二分类测量(无;Any)和categorically (none;仅提供评估/护理计划;服务吸收)。从0岁到4岁,每年测量任何WCV摄入量和推荐的WCV摄入量(随年龄变化)。传统的逻辑回归和兄弟固定效应(FE)回归估计了PNCC接收和WCV接收之间的关联。结果:人口统计学调整的兄弟姐妹FE回归-这是对未观察到的混淆的最佳控制-表明任何PNCC与儿童在0岁至0岁时接受任何WCV呈正相关。结论:PNCC可能改善儿童生命前2年的WCV出席率。研究结果强调了产科护理协调方案的潜力,以加强参与家庭预防性护理的连续性。
{"title":"Prenatal Care Coordination and Well-Child Visit Receipt in Early Childhood.","authors":"David C Mallinson","doi":"10.3122/jabfm.2024.240302R2","DOIUrl":"10.3122/jabfm.2024.240302R2","url":null,"abstract":"<p><strong>Introduction: </strong>This study evaluates participation in Wisconsin Medicaid's Prenatal Care Coordination (PNCC) program and its association with children's well-child visit (WCV) receipt.</p><p><strong>Study design: </strong>Data came from linked Wisconsin birth records (2011 to 2015) and Medicaid claims and enrollment data (2010 to 2019). The sample comprised 113,347 children with Medicaid-paid births and continuous Medicaid enrollment ranging from 12 to 48 months post-birth. A sibling subsample comprised of 35,373 children. PNCC receipt in pregnancy was measured dichotomously (none; any) and categorically (none; assessment/care plan only; service uptake). Any WCV receipt and recommended WCV receipt (which varied by age) were measured during each year from age 0 up to 4 years old. Conventional logistic regressions and sibling fixed effects (FE) regressions estimated associations between PNCC receipt and WCV receipt.</p><p><strong>Results: </strong>Demographic-adjusted sibling FE regressions-which best control for unobserved confounding-indicated that any PNCC was positively associated with children receiving any WCVs at age 0 to <1 year-old (OR 1.48; 95% CI 1.05-2.08) and at age 1 to <2 years old (OR 1.24; 95% CI 1.03-1.50). In addition, adjusted sibling FE regressions found that PNCC service uptake was associated with children receiving the recommended number of WCVs at age 0 to <1 year-old (OR 1.35; 95% CI 1.18-1.55).</p><p><strong>Conclusions: </strong>PNCC may improve children's WCV attendance in the first 2 years of life. Findings underscore the potential for obstetric care coordination programs to enhance the continuity of preventive care for participating families.</p>","PeriodicalId":50018,"journal":{"name":"Journal of the American Board of Family Medicine","volume":" ","pages":"513-538"},"PeriodicalIF":2.6,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12616804/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144823088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Conducting Research That Matters to Rural Practice and Communities. 开展对农村实践和社区至关重要的研究。
IF 2.6 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-09-15 DOI: 10.3122/jabfm.2024.240358R1
Sebastian T Tong, Melinda M Davis, Allison M Cole

Even though 20% of Americans live in rural communities, few research studies intentionally include or engage rural communities. The National Institutes of Health recently launched the CARE for Health™ Initiative that is initially focusing on engaging rural communities and primary care practices in research. In this commentary, we describe activities designed to improve rural clinical and community engagement in research led by two practice-based research networks (the Oregon Rural Practice Research Network and the WWAMI [Washington, Wyoming, Alaska, Montana and Idaho] region Practice and Research Network) funded through this initiative.

尽管20%的美国人生活在农村社区,但很少有研究有意地包括或涉及农村社区。美国国立卫生研究院(National Institutes of Health)最近启动了CARE for Health™倡议,最初的重点是让农村社区和初级保健实践参与研究。在这篇评论中,我们描述了旨在改善农村临床和社区参与研究的活动,这些研究由两个基于实践的研究网络(俄勒冈农村实践研究网络和WWAMI[华盛顿,怀俄明,阿拉斯加,蒙大拿州和爱达荷州]地区实践和研究网络)领导。
{"title":"Conducting Research That Matters to Rural Practice and Communities.","authors":"Sebastian T Tong, Melinda M Davis, Allison M Cole","doi":"10.3122/jabfm.2024.240358R1","DOIUrl":"10.3122/jabfm.2024.240358R1","url":null,"abstract":"<p><p>Even though 20% of Americans live in rural communities, few research studies intentionally include or engage rural communities. The National Institutes of Health recently launched the CARE for Health™ Initiative that is initially focusing on engaging rural communities and primary care practices in research. In this commentary, we describe activities designed to improve rural clinical and community engagement in research led by two practice-based research networks (the Oregon Rural Practice Research Network and the WWAMI [Washington, Wyoming, Alaska, Montana and Idaho] region Practice and Research Network) funded through this initiative.</p>","PeriodicalId":50018,"journal":{"name":"Journal of the American Board of Family Medicine","volume":" ","pages":"603-606"},"PeriodicalIF":2.6,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12616806/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144976615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Physician Experience of Discrimination in a Leadership and Well-Being Program. 医生在领导和福利项目中的歧视经验。
IF 2.6 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-09-15 DOI: 10.3122/jabfm.2024.240394R1
Elisabeth Callen, Kathryn Istas, Natabhona Mabachi, Tarin Clay

Introduction: Physician workforce shortages are expected to reach 48,000 primary care physicians by 2034 with burnout, discrimination (gender, race, and others), and harassment as contributors. Physicians experience discrimination and harassment on a daily basis and continue to work with patients who routinely discriminate against them, which can be directly related to burnout.

Methods: The American Academy of Family Physicians (AAFP) created the Leading Physician Well-Being Certificate Program to combat these issues. Surveys were sent to cohorts at multiple time points - beginning, middle, and end. Multiple evaluation instruments were included in these surveys, but for this analysis, we focused on the Everyday Discrimination Scale (EDS). For Cohort 1 (n = 88, 2021), they received the EDS midway through their cohort. For Cohort 2 (n = 62, 2022), they received the EDS at each time point, but received a Privilege Assessment midway through their cohort due to their answers on the EDS.

Results: Cohort 1 consistently rated the questions with higher levels of discrimination than Cohort 2 scholars. In general, Asian women from Cohort 1 experienced the most discrimination of all the groups (7 statements). For the Privilege Assessment, Asian and other women of color were more likely to indicate less privilege than other groups.

Discussion: Physicians taking the AAFP Leading Physician Well-Being Certificate Program reported have experienced discrimination and harassment. Certain physician groups experience higher levels of discrimination and harassment, and concurrent lower levels of privilege. While unfortunate, discrimination and harassment will continue to play a large role in physicians' lives.

到2034年,由于职业倦怠、歧视(性别、种族等)和骚扰等原因,医生劳动力短缺预计将达到4.8万名初级保健医生。医生每天都会经历歧视和骚扰,并继续与那些经常歧视他们的病人一起工作,这可能与倦怠直接相关。方法:美国家庭医生学会(AAFP)创建了领先的医生福利证书计划来解决这些问题。调查在开始、中期和结束的多个时间点发送给队列。这些调查包括多种评估工具,但在本次分析中,我们关注的是日常歧视量表(EDS)。对于队列1 (n = 88, 2021),他们在队列中途接受了EDS。对于队列2 (n = 62, 2022),他们在每个时间点都接受了EDS,但由于他们在EDS上的答案,他们在队列中间接受了特权评估。结果:队列1对歧视程度较高的问题的评分始终高于队列2的学者。总的来说,来自队列1的亚洲女性在所有群体中遭受的歧视最多(7个陈述)。在特权评估中,亚裔和其他有色人种女性比其他群体更有可能表现出较少的特权。讨论:据报道,参加AAFP领先医师幸福证书课程的医生经历过歧视和骚扰。某些医生群体经历了更高程度的歧视和骚扰,同时享有更低程度的特权。不幸的是,歧视和骚扰将继续在医生的生活中扮演重要角色。
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引用次数: 0
Evaluation of Asymptomatic Fasting Hypoglycemia in Outpatients Without Diabetes. 非糖尿病门诊患者无症状空腹低血糖的评价。
IF 2.6 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-09-15 DOI: 10.3122/jabfm.2024.240274R1
Tomás González-Vidal, Óscar Lado-Baleato, Carmen Fernández-Merino, Juan Sánchez-Castro, Manuela Alonso-Sampedro, Jessica Ares, Elías Delgado, Edelmiro Menéndez-Torre, Francisco Gude

Background: There are no studies on the clinical significance of asymptomatic hypoglycemia detected incidentally during routine testing.

Methods: Baseline fasting serum glucose was determined in 1333 individuals without diabetes (43.3% males, median age 50 years, range 18 to 91 years) to investigate the prevalence of hypoglycemia (fasting serum glucose <70 mg/dL) and the associated demographic, lifestyle, and metabolic factors. Individuals with baseline hypoglycemia were followed (median follow-up, 8.7 years) and assessed for hypoglycemia symptoms. Seven-day continuous glucose monitoring was performed in a subsample of 489 individuals.

Results: Baseline hypoglycemia was observed in 20 individuals (weighted prevalence, 1.58%, 95% confidence interval 0.87%-2.28%). Hypoglycemia was mild and asymptomatic in all cases (median, 67 mg/dL, range 63 to 69 mg/dL). The characteristics of those with hypoglycemia were similar to those with fasting serum glucose 70 to 80 mg/dL. Hypoglycemia was associated with female sex, younger age, and a more favorable metabolic profile (lower body mass index, glycohemoglobin and insulin resistance) than individuals with fasting serum glucose >80 mg/dL. Individuals with baseline hypoglycemia showed no distinct hypoglycemia features in continuous glucose monitoring (n = 9). During follow-up (n = 19), hypoglycemia in routine determinations, always mild, recurred in 42.1% of individuals, although the mean of successive glucose concentrations was higher than baseline in all cases. None of the individuals had symptoms that could constitute Whipple's triad (low serum glucose, symptoms of hypoglycemia, and symptomatic improvement after correction of hypoglycemia) during the follow-up period.

Conclusions: Detection of asymptomatic, mild hypoglycemia in routine blood tests is not indicative of disease and does not require further investigation.

背景:无症状性低血糖在常规检查中偶然发现的临床意义尚无研究。方法:对1333例无糖尿病患者(男性43.3%,中位年龄50岁,18 ~ 91岁)进行基线空腹血糖测定,以调查低血糖的患病率(空腹血糖)。结果:20例患者出现基线低血糖(加权患病率1.58%,95%可信区间0.87% ~ 2.28%)。所有病例的低血糖均为轻度且无症状(中位数为67 mg/dL,范围为63 - 69 mg/dL)。低血糖患者的特征与空腹血糖70 ~ 80 mg/dL的患者相似。低血糖与女性、年轻和较有利的代谢特征(较低的身体质量指数、糖蛋白和胰岛素抵抗)相关,而不是空腹血糖为80 mg/dL的个体。基线低血糖患者在连续血糖监测中没有明显的低血糖特征(n = 9)。在随访期间(n = 19),尽管所有病例的连续葡萄糖浓度平均值均高于基线,但42.1%的个体在常规检测中出现低血糖(总是轻度)复发。在随访期间,所有患者均未出现可构成惠普尔综合征的症状(低血糖、低血糖症状和低血糖纠正后症状改善)。结论:在常规血液检查中发现无症状、轻度低血糖不是疾病的指示,不需要进一步调查。
{"title":"Evaluation of Asymptomatic Fasting Hypoglycemia in Outpatients Without Diabetes.","authors":"Tomás González-Vidal, Óscar Lado-Baleato, Carmen Fernández-Merino, Juan Sánchez-Castro, Manuela Alonso-Sampedro, Jessica Ares, Elías Delgado, Edelmiro Menéndez-Torre, Francisco Gude","doi":"10.3122/jabfm.2024.240274R1","DOIUrl":"10.3122/jabfm.2024.240274R1","url":null,"abstract":"<p><strong>Background: </strong>There are no studies on the clinical significance of asymptomatic hypoglycemia detected incidentally during routine testing.</p><p><strong>Methods: </strong>Baseline fasting serum glucose was determined in 1333 individuals without diabetes (43.3% males, median age 50 years, range 18 to 91 years) to investigate the prevalence of hypoglycemia (fasting serum glucose <70 mg/dL) and the associated demographic, lifestyle, and metabolic factors. Individuals with baseline hypoglycemia were followed (median follow-up, 8.7 years) and assessed for hypoglycemia symptoms. Seven-day continuous glucose monitoring was performed in a subsample of 489 individuals.</p><p><strong>Results: </strong>Baseline hypoglycemia was observed in 20 individuals (weighted prevalence, 1.58%, 95% confidence interval 0.87%-2.28%). Hypoglycemia was mild and asymptomatic in all cases (median, 67 mg/dL, range 63 to 69 mg/dL). The characteristics of those with hypoglycemia were similar to those with fasting serum glucose 70 to 80 mg/dL. Hypoglycemia was associated with female sex, younger age, and a more favorable metabolic profile (lower body mass index, glycohemoglobin and insulin resistance) than individuals with fasting serum glucose >80 mg/dL. Individuals with baseline hypoglycemia showed no distinct hypoglycemia features in continuous glucose monitoring (n = 9). During follow-up (n = 19), hypoglycemia in routine determinations, always mild, recurred in 42.1% of individuals, although the mean of successive glucose concentrations was higher than baseline in all cases. None of the individuals had symptoms that could constitute Whipple's triad (low serum glucose, symptoms of hypoglycemia, and symptomatic improvement after correction of hypoglycemia) during the follow-up period.</p><p><strong>Conclusions: </strong>Detection of asymptomatic, mild hypoglycemia in routine blood tests is not indicative of disease and does not require further investigation.</p>","PeriodicalId":50018,"journal":{"name":"Journal of the American Board of Family Medicine","volume":" ","pages":"411-422"},"PeriodicalIF":2.6,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12616800/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144823072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Re: Performance Evaluation of the Generative Pre-Trained Transformer (GPT-4) on the Family Medicine In Training Examination. 生成式预训练变压器(GPT-4)在家庭医学培训考试中的表现评价。
IF 2.6 3区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-09-15 DOI: 10.3122/jabfm.2024.240404R0
Karim Hanna
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引用次数: 0
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Journal of the American Board of Family Medicine
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