首页 > 最新文献

Journal of Shoulder and Elbow Surgery最新文献

英文 中文
Older Age, Longer Symptom Duration, and Larger Sagittal Tear Size Predict Poorer Outcomes After Margin Convergence Repair of Massive Rotator Cuff Tears. 年龄越大,症状持续时间越长,矢状面撕裂大小越大,预示大量肩袖撕裂边缘收敛修复后预后较差。
IF 2.9 2区 医学 Q1 ORTHOPEDICS Pub Date : 2026-03-13 DOI: 10.1016/j.jse.2026.02.026
Ethem Burak Oklaz, Asim Ahmadov, Furkan Aral, Saffet Bugra Korkut, Huseyin Ozturk, Inci Hazal Ayas, Erdem Aras Sezgin, Ulunay Kanatli

Background: Margin convergence repair is a technique that embraces the philosophy of "harnessing the ox rather than roping the bull" for the repair of massive rotator cuff tears and has been shown to provide satisfactory functional outcomes. However, previous studies have generally relied on traditional scoring systems, leaving the clinical relevance of the outcomes from the patient's perspective and the effect of patient characteristics on these results largely unknown. Therefore, this study aimed to evaluate the minimal clinically important difference (MCID), substantial clinical benefit (SCB), and patient-acceptable symptom state (PASS) in patients who underwent arthroscopic margin convergence repair for massive rotator cuff tears and to analyze the impact of patient-related factors on functional recovery.Regarding predictors, we hypothesized that patients with older age and larger sagittal tear size would be less likely to achieve clinically meaningful outcomes.

Methods: This retrospective case series study was conducted on patients who underwent arthroscopic repair for massive rotator cuff tears between 2014 and 2023. Patients who underwent partial margin convergence repair using a combination of tendon-to-tendon sutures and anchor fixation were included in the study. The evaluation comprised the American Shoulder and Elbow Surgeons (ASES) score, Subjective Shoulder Value (SSV), Visual Analog Scale (VAS), and Range of Motion (ROM) measurements. The proportion of patients who achieved the thresholds for the MCID, SCB, and PASS were identified based on the ASES, SSV, and VAS. Regression analysis was conducted to determine the predictors of achieving these thresholds.

Results: The study included 60 patients (mean age 62.5 ± 9.2 years; mean follow-up 66.0 ± 36.1 months). The thresholds for MCID, PASS, and SCB were 24.5, 69.0, 41.5 for ASES; 25.0, 62.5, 32.5 for SSV; and 2.0, 2.5, 4.5 for VAS, respectively. The proportions of patients who achieved these thresholds were as follows: ASES (83%, 75%, 68%), SSV (78%, 73%, 72%), and VAS (83%, 77%, 63%). Older age was associated with lower odds of achieving MCID, PASS, and SCB, similarly a larger sagittal tear size and longer symptom duration reduced the odds of reaching PASS and SCB.

Conclusion: Partial repair using the margin convergence procedure is an effective treatment for massive rotator cuff tears, with the majority of patients achieving clinically meaningful outcomes at a minimum follow-up of two years. Lower rates of clinical success can be expected in patients with older age, longer symptom duration, and larger sagittal tear size.

背景:边缘收敛修复是一种包含“驾驭公牛而不是束缚公牛”的哲学的技术,用于修复大量的肩袖撕裂,并已被证明提供令人满意的功能结果。然而,以前的研究通常依赖于传统的评分系统,从患者的角度来看,结果的临床相关性以及患者特征对这些结果的影响在很大程度上是未知的。因此,本研究旨在评估关节镜下边缘会聚修复大面积肩袖撕裂患者的最小临床重要差异(MCID)、实质性临床获益(SCB)和患者可接受症状状态(PASS),并分析患者相关因素对功能恢复的影响。关于预测因素,我们假设年龄较大、矢状面撕裂大小较大的患者不太可能获得有临床意义的结果。方法:回顾性分析2014年至2023年间接受关节镜修复的大规模肩袖撕裂患者。采用肌腱对肌腱缝合和锚定固定联合进行部分边缘收敛修复的患者被纳入研究。评估包括美国肩关节外科医生评分、主观肩部值(SSV)、视觉模拟量表(VAS)和活动范围(ROM)测量。根据asa、SSV和VAS确定达到MCID、SCB和PASS阈值的患者比例。进行回归分析以确定达到这些阈值的预测因素。结果:纳入60例患者,平均年龄62.5±9.2岁,平均随访66.0±36.1个月。asas的MCID、PASS和SCB阈值分别为24.5、69.0和41.5;SSV为25.0、62.5、32.5;VAS评分分别为2.0、2.5、4.5。达到这些阈值的患者比例如下:as (83%, 75%, 68%), SSV(78%, 73%, 72%)和VAS(83%, 77%, 63%)。年龄越大,出现MCID、PASS和SCB的几率越低,同样,矢状面撕裂大小越大,症状持续时间越长,出现PASS和SCB的几率也越低。结论:采用边缘收敛术部分修复是治疗大面积肩袖撕裂的有效方法,大多数患者在至少两年的随访后获得了有临床意义的结果。对于年龄较大、症状持续时间较长、矢状面撕裂大小较大的患者,临床成功率较低。
{"title":"Older Age, Longer Symptom Duration, and Larger Sagittal Tear Size Predict Poorer Outcomes After Margin Convergence Repair of Massive Rotator Cuff Tears.","authors":"Ethem Burak Oklaz, Asim Ahmadov, Furkan Aral, Saffet Bugra Korkut, Huseyin Ozturk, Inci Hazal Ayas, Erdem Aras Sezgin, Ulunay Kanatli","doi":"10.1016/j.jse.2026.02.026","DOIUrl":"https://doi.org/10.1016/j.jse.2026.02.026","url":null,"abstract":"<p><strong>Background: </strong>Margin convergence repair is a technique that embraces the philosophy of \"harnessing the ox rather than roping the bull\" for the repair of massive rotator cuff tears and has been shown to provide satisfactory functional outcomes. However, previous studies have generally relied on traditional scoring systems, leaving the clinical relevance of the outcomes from the patient's perspective and the effect of patient characteristics on these results largely unknown. Therefore, this study aimed to evaluate the minimal clinically important difference (MCID), substantial clinical benefit (SCB), and patient-acceptable symptom state (PASS) in patients who underwent arthroscopic margin convergence repair for massive rotator cuff tears and to analyze the impact of patient-related factors on functional recovery.Regarding predictors, we hypothesized that patients with older age and larger sagittal tear size would be less likely to achieve clinically meaningful outcomes.</p><p><strong>Methods: </strong>This retrospective case series study was conducted on patients who underwent arthroscopic repair for massive rotator cuff tears between 2014 and 2023. Patients who underwent partial margin convergence repair using a combination of tendon-to-tendon sutures and anchor fixation were included in the study. The evaluation comprised the American Shoulder and Elbow Surgeons (ASES) score, Subjective Shoulder Value (SSV), Visual Analog Scale (VAS), and Range of Motion (ROM) measurements. The proportion of patients who achieved the thresholds for the MCID, SCB, and PASS were identified based on the ASES, SSV, and VAS. Regression analysis was conducted to determine the predictors of achieving these thresholds.</p><p><strong>Results: </strong>The study included 60 patients (mean age 62.5 ± 9.2 years; mean follow-up 66.0 ± 36.1 months). The thresholds for MCID, PASS, and SCB were 24.5, 69.0, 41.5 for ASES; 25.0, 62.5, 32.5 for SSV; and 2.0, 2.5, 4.5 for VAS, respectively. The proportions of patients who achieved these thresholds were as follows: ASES (83%, 75%, 68%), SSV (78%, 73%, 72%), and VAS (83%, 77%, 63%). Older age was associated with lower odds of achieving MCID, PASS, and SCB, similarly a larger sagittal tear size and longer symptom duration reduced the odds of reaching PASS and SCB.</p><p><strong>Conclusion: </strong>Partial repair using the margin convergence procedure is an effective treatment for massive rotator cuff tears, with the majority of patients achieving clinically meaningful outcomes at a minimum follow-up of two years. Lower rates of clinical success can be expected in patients with older age, longer symptom duration, and larger sagittal tear size.</p>","PeriodicalId":50051,"journal":{"name":"Journal of Shoulder and Elbow Surgery","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147464132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Current treatment options for severe glenoid bone loss in revision shoulder arthroplasty: a systematic review and meta-analysis. 翻修肩关节置换术中严重盂骨丢失的当前治疗选择:系统回顾和荟萃分析。
IF 2.9 2区 医学 Q1 ORTHOPEDICS Pub Date : 2026-03-13 DOI: 10.1016/j.jse.2026.02.025
Mina Shenouda, James H Padley, Necati B Eravşar, Eve R Glenn, Alexander R Zhu, Russell Edafetanure-Ibeh, Radhakrishna Kantanavar, Edward G McFarland

Background: Failed shoulder arthroplasty often presents with glenoid bone loss, posing a challenge for both surgeons and patients. This study aimed to evaluate the available revision strategies for failed shoulder arthroplasty in the presence of severe glenoid bone loss. Severe bone loss was defined as a glenoid that is not capable of reconstruction using a standard reverse total shoulder glenoid or augmented baseplate.

Methods: Following the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses, PubMed and Google Scholar were systematically searched for revision -shoulder- arthroplasty - glenoid bone loss by two authors independently. Statistical analysis was performed using RevMan software.

Results: Initially, 249 references were retrieved. After duplicate removal and abstract and title screening, 40 full-text studies comprising of 656 patients met eligibility criteria. The mean patient age was 67.7 years (range 62.4-71.2), with a mean follow-up of 33 months (range 16-50). Regarding functional outcomes, custom glenoid implants demonstrated the greatest improvements in ASES and Constant scores, with mean differences (MDs) of 42.4 and 35.8, respectively (P < .001 for both). Custom implants also provided the best pain relief (MD 5.79, P < .001). For range of motion, bone grafting with reverse total shoulder arthroplasty (rTSA) provided the best improvements in external rotation (MD 21.0°) and forward flexion (MD 67.4°) (P < .001 for both).

Conclusion: Custom glenoid implants provided the best functional outcomes and pain relief in revision shoulder arthroplasty with glenoid bone loss. The findings of this study would suggest that given in the short term of superior performance in improving pain, with higher ASES and Constant scores, custom glenoid components warrant further long term study of these issues and long term survival of the implants.

背景:肩关节置换术失败常伴有关节盂骨丢失,这对外科医生和患者都是一个挑战。本研究旨在评估严重肩关节骨丢失的肩关节置换术失败后可用的翻修策略。严重骨丢失被定义为不能使用标准的反向全肩胛盂或增强基板重建肩胛盂。方法:遵循系统评价和荟萃分析的首选报告项目的指导方针,PubMed和谷歌Scholar由两位作者独立系统地检索了翻修-肩关节置换术-肩关节盂骨丢失。采用RevMan软件进行统计分析。结果:最初,检索到249篇文献。经过重复删除、摘要和标题筛选,包含656例患者的40项全文研究符合入选标准。患者平均年龄为67.7岁(范围62.4-71.2),平均随访时间为33个月(范围16-50)。在功能结果方面,自定义关节盂植入物在ase和Constant评分方面表现出最大的改善,平均差异(MDs)分别为42.4和35.8 (P < 0.001)。定制种植体也提供了最好的疼痛缓解(MD 5.79, P < 0.001)。在活动范围方面,植骨联合反向全肩关节置换术(rTSA)在外旋(MD 21.0°)和前屈(MD 67.4°)方面提供了最好的改善(两者P < 0.001)。结论:自定义肩关节假体在肩关节盂骨丢失的翻修肩关节置换术中提供了最佳的功能效果和疼痛缓解。本研究的结果表明,鉴于短期内在改善疼痛方面的优异表现,具有较高的ase和Constant评分,定制的关节盂假体值得进一步的长期研究这些问题和植入物的长期生存。
{"title":"Current treatment options for severe glenoid bone loss in revision shoulder arthroplasty: a systematic review and meta-analysis.","authors":"Mina Shenouda, James H Padley, Necati B Eravşar, Eve R Glenn, Alexander R Zhu, Russell Edafetanure-Ibeh, Radhakrishna Kantanavar, Edward G McFarland","doi":"10.1016/j.jse.2026.02.025","DOIUrl":"https://doi.org/10.1016/j.jse.2026.02.025","url":null,"abstract":"<p><strong>Background: </strong>Failed shoulder arthroplasty often presents with glenoid bone loss, posing a challenge for both surgeons and patients. This study aimed to evaluate the available revision strategies for failed shoulder arthroplasty in the presence of severe glenoid bone loss. Severe bone loss was defined as a glenoid that is not capable of reconstruction using a standard reverse total shoulder glenoid or augmented baseplate.</p><p><strong>Methods: </strong>Following the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses, PubMed and Google Scholar were systematically searched for revision -shoulder- arthroplasty - glenoid bone loss by two authors independently. Statistical analysis was performed using RevMan software.</p><p><strong>Results: </strong>Initially, 249 references were retrieved. After duplicate removal and abstract and title screening, 40 full-text studies comprising of 656 patients met eligibility criteria. The mean patient age was 67.7 years (range 62.4-71.2), with a mean follow-up of 33 months (range 16-50). Regarding functional outcomes, custom glenoid implants demonstrated the greatest improvements in ASES and Constant scores, with mean differences (MDs) of 42.4 and 35.8, respectively (P < .001 for both). Custom implants also provided the best pain relief (MD 5.79, P < .001). For range of motion, bone grafting with reverse total shoulder arthroplasty (rTSA) provided the best improvements in external rotation (MD 21.0°) and forward flexion (MD 67.4°) (P < .001 for both).</p><p><strong>Conclusion: </strong>Custom glenoid implants provided the best functional outcomes and pain relief in revision shoulder arthroplasty with glenoid bone loss. The findings of this study would suggest that given in the short term of superior performance in improving pain, with higher ASES and Constant scores, custom glenoid components warrant further long term study of these issues and long term survival of the implants.</p>","PeriodicalId":50051,"journal":{"name":"Journal of Shoulder and Elbow Surgery","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147464192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development and psychometric testing of a novel scale for shoulder assessment. 一种新的肩部评估量表的开发和心理测量学测试。
IF 2.9 2区 医学 Q1 ORTHOPEDICS Pub Date : 2026-03-13 DOI: 10.1016/j.jse.2026.02.022
Seyedeh Zahra Mousavi, Rashelle J Musci, Brienna K Buchanan, Umasuthan Srikumaran

Background: Current patient-reported outcome measures (PROMs) are long, have complex scoring systems, suffer from ceiling and floor effects, are not universally applicable, and have a high administrative burden. In response, we have developed the Subjective Shoulder Scale (S3), a novel PROM designed to overcome these limitations and provide a comprehensive, efficient, and patient-centered evaluation of 7 key domains.

Methods: Items for S3 were generated by reviewing existing questionnaires and refined using input from patients and an expert panel. Seven questions assess pain, range of motion, strength, shoulder stability, activities of daily living, sports and leisure activities, and mental well-being. After pilot testing in 20 participants, test-retest reliability was evaluated in 100 participants by calculating Cronbach's alpha and the intraclass correlation coefficient. To test validity and responsiveness, 124 participants completed both the S3 and the American Shoulder and Elbow Surgeons questionnaire before and after undergoing various shoulder procedures. Pearson's correlation coefficients, exploratory factor analysis, and responsiveness were determined by calculating the effect size and establishing thresholds for the minimal clinically important difference, substantial clinical benefit, and patient-acceptable symptom state.

Results: Pilot testing confirmed clarity, relevance, readability, and ease of use. In the full psychometric evaluation cohort of 244 participants (mean ± standard deviation age 59 ± 13 years; 50% females), the S3 exhibited excellent test-retest reliability (intraclass correlation coefficient = 0.96) and high internal consistency (Cronbach's α = 0.93). No ceiling or floor effects were observed. Exploratory factor analysis supported a unidimensional structure, and convergent validity was established through a strong positive correlation with the American Shoulder and Elbow Surgeons questionnaire (r = 0.71, p < .001). S3 is also responsive, with thresholds of 12.4 points for minimal clinically important difference, 19.9 points for substantial clinical benefit, and 38-83 points for patient acceptable symptom state.

Conclusion: S3 is a reliable, valid, responsive PROM for capturing the effects of diverse shoulder conditions. By addressing weaknesses of existing questionnaires, S3 may facilitate personalized treatment planning through more efficient, meaningful patient evaluations.

背景:目前的患者报告的结果测量(PROMs)很长,有复杂的评分系统,有上限和下限效应,不是普遍适用的,并且有很高的管理负担。为此,我们开发了主观肩部量表(S3),这是一种新颖的PROM,旨在克服这些局限性,并对7个关键领域提供全面、有效和以患者为中心的评估。方法:S3的项目是通过回顾现有的问卷,并根据患者和专家小组的意见进行改进而产生的。七个问题评估疼痛、活动范围、力量、肩部稳定性、日常生活活动、运动和休闲活动以及心理健康。在20名被试进行预试后,通过计算Cronbach’s alpha和类内相关系数对100名被试进行重测信度评估。为了测试有效性和反应性,124名参与者在接受各种肩部手术之前和之后完成了S3和美国肩关节外科医生的问卷调查。Pearson相关系数、探索性因子分析和反应性通过计算效应大小和建立最小临床重要差异、实质性临床获益和患者可接受症状状态的阈值来确定。结果:初步测试证实了清晰、相关、可读性和易用性。在244名参与者(平均±标准差年龄59±13岁,女性占50%)的全心理测量评估队列中,S3具有优异的重测信度(类内相关系数= 0.96)和高内部一致性(Cronbach's α = 0.93)。没有观察到天花板或地板效应。探索性因素分析支持一维结构,并通过与美国肩肘外科医生问卷的强正相关(r = 0.71, p < 0.001)建立了趋同效度。S3也是有效的,最小临床重要差异的阈值为12.4分,显著临床获益的阈值为19.9分,患者可接受症状状态的阈值为38-83分。结论:S3是一种可靠、有效、反应灵敏的PROM,可捕获不同肩部状况的影响。通过解决现有问卷的弱点,S3可以通过更有效、更有意义的患者评估来促进个性化治疗计划。
{"title":"Development and psychometric testing of a novel scale for shoulder assessment.","authors":"Seyedeh Zahra Mousavi, Rashelle J Musci, Brienna K Buchanan, Umasuthan Srikumaran","doi":"10.1016/j.jse.2026.02.022","DOIUrl":"https://doi.org/10.1016/j.jse.2026.02.022","url":null,"abstract":"<p><strong>Background: </strong>Current patient-reported outcome measures (PROMs) are long, have complex scoring systems, suffer from ceiling and floor effects, are not universally applicable, and have a high administrative burden. In response, we have developed the Subjective Shoulder Scale (S3), a novel PROM designed to overcome these limitations and provide a comprehensive, efficient, and patient-centered evaluation of 7 key domains.</p><p><strong>Methods: </strong>Items for S3 were generated by reviewing existing questionnaires and refined using input from patients and an expert panel. Seven questions assess pain, range of motion, strength, shoulder stability, activities of daily living, sports and leisure activities, and mental well-being. After pilot testing in 20 participants, test-retest reliability was evaluated in 100 participants by calculating Cronbach's alpha and the intraclass correlation coefficient. To test validity and responsiveness, 124 participants completed both the S3 and the American Shoulder and Elbow Surgeons questionnaire before and after undergoing various shoulder procedures. Pearson's correlation coefficients, exploratory factor analysis, and responsiveness were determined by calculating the effect size and establishing thresholds for the minimal clinically important difference, substantial clinical benefit, and patient-acceptable symptom state.</p><p><strong>Results: </strong>Pilot testing confirmed clarity, relevance, readability, and ease of use. In the full psychometric evaluation cohort of 244 participants (mean ± standard deviation age 59 ± 13 years; 50% females), the S3 exhibited excellent test-retest reliability (intraclass correlation coefficient = 0.96) and high internal consistency (Cronbach's α = 0.93). No ceiling or floor effects were observed. Exploratory factor analysis supported a unidimensional structure, and convergent validity was established through a strong positive correlation with the American Shoulder and Elbow Surgeons questionnaire (r = 0.71, p < .001). S3 is also responsive, with thresholds of 12.4 points for minimal clinically important difference, 19.9 points for substantial clinical benefit, and 38-83 points for patient acceptable symptom state.</p><p><strong>Conclusion: </strong>S3 is a reliable, valid, responsive PROM for capturing the effects of diverse shoulder conditions. By addressing weaknesses of existing questionnaires, S3 may facilitate personalized treatment planning through more efficient, meaningful patient evaluations.</p>","PeriodicalId":50051,"journal":{"name":"Journal of Shoulder and Elbow Surgery","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147464204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Social Determinants of Health and Outcomes in Proximal Humerus Fractures based on Surgery Type. 基于手术类型的肱骨近端骨折健康和预后的社会决定因素
IF 2.9 2区 医学 Q1 ORTHOPEDICS Pub Date : 2026-03-13 DOI: 10.1016/j.jse.2026.02.027
Kai Zhu, Mary Hennekes, Chimdi Obinero, Christian Freitag, Frass Ahmed, Mahdi Mazeh, Jared Mahylis, Stephanie Muh

Introduction: Proximal humerus fractures (PHFs) account for 5-6% of all adult fractures. The optimal surgical management for PHFs remains under debate with two of the most common operations being open reduction and internal fixation (ORIF) and reverse total shoulder arthroplasty (rTSA). Social determinants of health (SDOH) has gained particular attention in many medical fields due to its relationship to health outcomes with the Social Vulnerability Index (SVI) as an example of an adopted measure of geographic disadvantage. The purpose of this study was to investigate the associations between SVI percentiles and insurance status to adverse postoperative outcomes following surgical treatment of PHFs using either ORIF or rTSA.

Methods: This was a retrospective chart review of patients with PHFs who were treated surgically with either ORIF or rTSA between 2016 to 2023 at a large metropolitan healthcare system. Patient demographics were recorded, and SVI percentiles were determined using patient addresses. Demographic variables were descriptively analyzed based on type of surgery and SVI quartile group. Univariate and multivariate logistic regression analyses were conducted to investigate associations between SVI percentiles and insurance status to adverse postoperative outcomes.

Results: A total of 215 patients with PHFs were included in this study, with 118 in the ORIF group and 97 in the rTSA group. From the multivariate analysis in the ORIF group, there was an association with increasing SVI percentiles and higher odds of returning to the emergency department (ED) (OR = 1.023, p value = 0.002) and having a hospital readmission (OR = 1.028, p value = 0.001). Additionally, patients in the ORIF group with private insurance had lower odds of hospital readmission (OR = 0.077, p value = 0.001) compared to patients who had Medicaid. Patients in the rTSA group did not have significant associations with adverse postoperative outcomes based on increasing SVI percentiles or insurance status.

Conclusion: This study demonstrated that higher SVI percentiles and Medicaid status were associated with adverse postoperative outcomes in patients who underwent ORIF for treatment of their PHFs. Higher SVI percentiles and insurance status did not appear to be associated with adverse postoperative outcomes in the rTSA group. This study highlighted the way in which SDOH and choice of surgery relate to adverse postoperative outcomes in patients with PHFs.

简介:肱骨近端骨折(phf)占所有成人骨折的5-6%。phf的最佳手术治疗仍存在争议,最常见的两种手术是切开复位内固定(ORIF)和反向全肩关节置换术(rTSA)。健康的社会决定因素(SDOH)在许多医学领域受到特别关注,因为它与健康结果之间的关系与社会脆弱性指数(SVI)有关,后者是一种已采用的地理劣势衡量标准。本研究的目的是调查SVI百分位数和保险状况与使用ORIF或rTSA治疗phf手术后不良术后结果之间的关系。方法:回顾性分析2016年至2023年在大型城市医疗保健系统中接受ORIF或rTSA手术治疗的phf患者。记录患者人口统计数据,并根据患者地址确定SVI百分位数。根据手术类型和SVI四分位数组对人口学变量进行描述性分析。进行单因素和多因素logistic回归分析,以调查SVI百分位数和保险状况与术后不良结果之间的关系。结果:本研究共纳入215例phf患者,其中ORIF组118例,rTSA组97例。从ORIF组的多变量分析来看,SVI百分位数的增加与返回急诊科(ED) (OR = 1.023, p值= 0.002)和再次住院(OR = 1.028, p值= 0.001)的几率较高有关。此外,与有医疗补助的患者相比,有私人保险的ORIF组患者再入院的几率更低(OR = 0.077, p值= 0.001)。rTSA组患者与SVI百分位数增加或保险状况的不良术后结果没有显著关联。结论:本研究表明,较高的SVI百分位数和医疗补助状况与接受ORIF治疗phf的患者的不良术后结局相关。在rTSA组中,较高的SVI百分位数和保险状况似乎与不良的术后结果无关。这项研究强调了SDOH和手术选择与phf患者不良术后结果的关系。
{"title":"Social Determinants of Health and Outcomes in Proximal Humerus Fractures based on Surgery Type.","authors":"Kai Zhu, Mary Hennekes, Chimdi Obinero, Christian Freitag, Frass Ahmed, Mahdi Mazeh, Jared Mahylis, Stephanie Muh","doi":"10.1016/j.jse.2026.02.027","DOIUrl":"https://doi.org/10.1016/j.jse.2026.02.027","url":null,"abstract":"<p><strong>Introduction: </strong>Proximal humerus fractures (PHFs) account for 5-6% of all adult fractures. The optimal surgical management for PHFs remains under debate with two of the most common operations being open reduction and internal fixation (ORIF) and reverse total shoulder arthroplasty (rTSA). Social determinants of health (SDOH) has gained particular attention in many medical fields due to its relationship to health outcomes with the Social Vulnerability Index (SVI) as an example of an adopted measure of geographic disadvantage. The purpose of this study was to investigate the associations between SVI percentiles and insurance status to adverse postoperative outcomes following surgical treatment of PHFs using either ORIF or rTSA.</p><p><strong>Methods: </strong>This was a retrospective chart review of patients with PHFs who were treated surgically with either ORIF or rTSA between 2016 to 2023 at a large metropolitan healthcare system. Patient demographics were recorded, and SVI percentiles were determined using patient addresses. Demographic variables were descriptively analyzed based on type of surgery and SVI quartile group. Univariate and multivariate logistic regression analyses were conducted to investigate associations between SVI percentiles and insurance status to adverse postoperative outcomes.</p><p><strong>Results: </strong>A total of 215 patients with PHFs were included in this study, with 118 in the ORIF group and 97 in the rTSA group. From the multivariate analysis in the ORIF group, there was an association with increasing SVI percentiles and higher odds of returning to the emergency department (ED) (OR = 1.023, p value = 0.002) and having a hospital readmission (OR = 1.028, p value = 0.001). Additionally, patients in the ORIF group with private insurance had lower odds of hospital readmission (OR = 0.077, p value = 0.001) compared to patients who had Medicaid. Patients in the rTSA group did not have significant associations with adverse postoperative outcomes based on increasing SVI percentiles or insurance status.</p><p><strong>Conclusion: </strong>This study demonstrated that higher SVI percentiles and Medicaid status were associated with adverse postoperative outcomes in patients who underwent ORIF for treatment of their PHFs. Higher SVI percentiles and insurance status did not appear to be associated with adverse postoperative outcomes in the rTSA group. This study highlighted the way in which SDOH and choice of surgery relate to adverse postoperative outcomes in patients with PHFs.</p>","PeriodicalId":50051,"journal":{"name":"Journal of Shoulder and Elbow Surgery","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147464124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Source of Lateralization in Reverse Total Shoulder Arthroplasty Matters: A Comparison of Glenoid and Humeral Lateralization on Rotator Cuff Biomechanics. 反向全肩关节置换术中侧移的来源:肩关节和肱骨侧移对肩袖生物力学的比较。
IF 2.9 2区 医学 Q1 ORTHOPEDICS Pub Date : 2026-03-13 DOI: 10.1016/j.jse.2026.02.021
Christopher M Brusalis, Jonathan Glenday, Michael C Fu, Joshua S Dines, Theodore A Blaine, David M Dines, Lawrence V Gulotta, Samuel A Taylor, Andreas Kontaxis
<p><strong>Introduction: </strong>Compared to the traditional Grammont design, modern reverse total shoulder arthroplasty (rTSA) implant designs often introduce lateralization of the glenoid and/or humeral components. This study aimed to evaluate the impact of different strategies for achieving lateralization (i.e. humeral or glenoid lateralization) in rTSA implant design on rotator cuff biomechanics.</p><p><strong>Methods: </strong>Computed tomography scans from 16 non-osteoarthritic subjects were used to build customized computational three-dimensional shoulder models based upon the Newcastle Shoulder Model. Four rTSA implant constructs were created: 1) medialized glenoid-medialized humerus (MG-MH); 2) medialized glenoid-lateralized humerus (MG-LH); 3) lateralized glenoid-medialized humerus (LG-MH); and 4) lateralized glenoid-lateralized humerus (LG-LH). All constructs employed a humeral stem with 135° neck-shaft angle where the diameter of the glenosphere was 36mm. Simulated rTSA constructs included a subscapularis tendon repaired to its native attachment on the lesser tuberosity. For each design construct, moment arms for both the subscapularis and infraspinatus were calculated for four motions: humeral elevation in frontal and scapular plane, internal/external rotation at 20° and 90° of abduction. Moment arms for each construct were also compared to those in a native shoulder.</p><p><strong>Results: </strong>All rTSA constructs influenced the moment arms of the rotator cuff muscles. During humeral elevation, both the subscapularis and infraspinatus exhibited increased adductive moment arms compared to the native shoulder, particularly at lower angles of elevation (0-80° in abduction and 0-50° in the scapular plane). Glenoid lateralization did not significantly affect these changes; however, humeral lateralization enhanced the adductive moment arms of both muscles. Additionally, all rTSA constructs altered the internal and external rotation moment arms of the RC muscles relative to the native shoulder. The subscapularis showed increased internal rotation moment arms that got larger than the native shoulder only after 40° of internal rotation, while the infraspinatus demonstrated increased external rotation moment arms during all external rotation range of motion. Again, glenoid lateralization did not significantly impact these rotational moment arms, whereas humeral lateralization led to an increase in both internal (subscapularis) and external (infraspinatus) rotation moment arms.</p><p><strong>Conclusions: </strong>While glenoid lateralization of an rTSA implant construct does not substantially alter rotator cuff moment arms, humeral lateralization may have a dual effect: potentially introducing an antagonistic adductive moment relative to the deltoid during early abduction, while also augmenting beneficial rotational moment arms-namely, increased internal rotation from the subscapularis and increased external rotation from the infraspinatu
简介:与传统的gramont设计相比,现代的反向全肩关节置换术(rTSA)植入设计通常会引入肩关节和/或肱骨部件的侧化。本研究旨在评估rTSA植入物设计中实现侧化(即肱骨或肩关节侧化)的不同策略对肩袖生物力学的影响。方法:采用16例非骨关节炎患者的计算机断层扫描,在Newcastle肩关节模型的基础上建立定制的计算三维肩关节模型。制作了四种rTSA植入物:1)中位盂-中位肱骨(MG-MH);2)肱骨内侧盂-外侧化(MG-LH);3)肩关节内侧偏侧肱骨(LG-MH);4)肩关节外侧-肱骨外侧化(lh - lh)。所有构建体均采用135°颈轴角的肱骨柄,关节球直径为36mm。模拟rTSA结构包括肩胛下肌腱修复到小结节的天然附着。对于每个设计结构,肩胛下肌和冈下肌的矩臂计算了四种运动:肱骨在额骨和肩胛骨平面上的抬高,外展20°和90°的内/外旋。每种结构的力臂也与天然肩部的力臂进行了比较。结果:所有rTSA结构都会影响肩袖肌的力臂。在肱骨抬高过程中,肩胛下肌和冈下肌的内收力矩臂均比正常肩部增加,尤其是在较低的抬高角度(外展0-80°,肩胛平面0-50°)。关节盂侧移对这些变化没有显著影响;然而,肱骨侧移增强了两组肌肉的内收力矩臂。此外,所有rTSA结构都改变了RC肌肉相对于原肩的内、外旋转力矩臂。肩胛下肌内旋力矩臂增加,仅在内旋40°后才比原肩大,而冈下肌在所有外旋运动范围内均表现出外旋力矩臂增加。同样,肩关节侧移对旋转力矩臂没有显著影响,而肱骨侧移导致内(肩胛下肌)和外(冈下肌)旋转力矩臂的增加。结论:虽然rTSA植入物的肩胛盂侧化不会实质性地改变肩袖力矩臂,但肱骨侧化可能有双重作用:在早期外展期间可能引入相对于三角肌的拮抗内收力矩,同时也增加有益的旋转力矩臂——即肩胛下肌的内旋增加和棘下肌的外旋增加。
{"title":"Source of Lateralization in Reverse Total Shoulder Arthroplasty Matters: A Comparison of Glenoid and Humeral Lateralization on Rotator Cuff Biomechanics.","authors":"Christopher M Brusalis, Jonathan Glenday, Michael C Fu, Joshua S Dines, Theodore A Blaine, David M Dines, Lawrence V Gulotta, Samuel A Taylor, Andreas Kontaxis","doi":"10.1016/j.jse.2026.02.021","DOIUrl":"https://doi.org/10.1016/j.jse.2026.02.021","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;Compared to the traditional Grammont design, modern reverse total shoulder arthroplasty (rTSA) implant designs often introduce lateralization of the glenoid and/or humeral components. This study aimed to evaluate the impact of different strategies for achieving lateralization (i.e. humeral or glenoid lateralization) in rTSA implant design on rotator cuff biomechanics.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;Computed tomography scans from 16 non-osteoarthritic subjects were used to build customized computational three-dimensional shoulder models based upon the Newcastle Shoulder Model. Four rTSA implant constructs were created: 1) medialized glenoid-medialized humerus (MG-MH); 2) medialized glenoid-lateralized humerus (MG-LH); 3) lateralized glenoid-medialized humerus (LG-MH); and 4) lateralized glenoid-lateralized humerus (LG-LH). All constructs employed a humeral stem with 135° neck-shaft angle where the diameter of the glenosphere was 36mm. Simulated rTSA constructs included a subscapularis tendon repaired to its native attachment on the lesser tuberosity. For each design construct, moment arms for both the subscapularis and infraspinatus were calculated for four motions: humeral elevation in frontal and scapular plane, internal/external rotation at 20° and 90° of abduction. Moment arms for each construct were also compared to those in a native shoulder.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;All rTSA constructs influenced the moment arms of the rotator cuff muscles. During humeral elevation, both the subscapularis and infraspinatus exhibited increased adductive moment arms compared to the native shoulder, particularly at lower angles of elevation (0-80° in abduction and 0-50° in the scapular plane). Glenoid lateralization did not significantly affect these changes; however, humeral lateralization enhanced the adductive moment arms of both muscles. Additionally, all rTSA constructs altered the internal and external rotation moment arms of the RC muscles relative to the native shoulder. The subscapularis showed increased internal rotation moment arms that got larger than the native shoulder only after 40° of internal rotation, while the infraspinatus demonstrated increased external rotation moment arms during all external rotation range of motion. Again, glenoid lateralization did not significantly impact these rotational moment arms, whereas humeral lateralization led to an increase in both internal (subscapularis) and external (infraspinatus) rotation moment arms.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;While glenoid lateralization of an rTSA implant construct does not substantially alter rotator cuff moment arms, humeral lateralization may have a dual effect: potentially introducing an antagonistic adductive moment relative to the deltoid during early abduction, while also augmenting beneficial rotational moment arms-namely, increased internal rotation from the subscapularis and increased external rotation from the infraspinatu","PeriodicalId":50051,"journal":{"name":"Journal of Shoulder and Elbow Surgery","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147464197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Lateral Para-olecranon Approach for Unlinked Total Elbow Arthroplasty with the Kudo Prosthesis in Patients with Rheumatoid Arthritis: Midterm Outcomes. 外侧鹰嘴旁入路应用Kudo假体治疗类风湿关节炎患者无连接全肘关节置换:中期结果
IF 2.9 2区 医学 Q1 ORTHOPEDICS Pub Date : 2026-03-13 DOI: 10.1016/j.jse.2026.02.023
Shosuke Akita, Naomi Sato, Koji Yachi, Shogo Ikeda, Shunichi Henmi, Takenori Oda

Background: The lateral para-olecranon approach preserves triceps integrity while providing adequate exposure for unlinked total elbow arthroplasty (TEA). However, its effectiveness in patients with rheumatoid arthritis (RA) remains unclear. This study aimed to evaluate midterm clinical and radiographic outcomes of unlinked TEA performed via the lateral para-olecranon approach in patients with RA, focusing on triceps function, range of motion (ROM), strength, and complications.

Methods: Among 43 elbows (39 patients) undergoing unlinked TEA with the Kudo prosthesis via the lateral para-olecranon approach, 2 were excluded because of death and 1 underwent implant removal for deep infection. The final clinical cohort comprised 40 elbows in 36 patients (27 women, 9 men; mean age, 64 ± 13 years; mean follow-up, 73 ± 33 months). Preoperative radiographs showed Larsen grade III in 12 elbows (30%) and grade IV in 28 elbows (70%). Outcomes included active ROM; flexion and extension strength measured by handheld dynamometry; manual muscle testing (MMT); Mayo Elbow Performance Score (MEPS); and radiographic assessment.

Results: All ROM parameters improved significantly: flexion, 121° ± 17° to 137° ± 6°; extension, -34° ± 17° to -26° ± 10°; pronation, 64° ± 16° to 76° ± 15°; and supination, 59° ± 28° to 73° ± 24° (P < .001 for flexion and pronation; P = .0022 for extension; P = .0010 for supination). Flexion and extension strength increased from 16 ± 14 to 26 ± 20 N (P = .0016) and from 13 ± 12 to 23 ± 16 N (P < .001). All elbows maintained MMT grade 5 triceps strength. Mean MEPS increased from 55 ± 9 to 92 ± 8 (P < .001). Among 40 elbows with implants in situ, radiographic evaluation revealed no type III or IV lucency. Kaplan-Meier analysis of 41 elbows demonstrated 97.1% implant survival (95% confidence interval, 81.4%-99.6%). Complications included 2 intraoperative medial epicondyle fractures (5%) and 1 deep infection requiring implant removal (2%). No triceps insufficiency, subluxation, or nerve palsy occurred.

Conclusions: Unlinked TEA performed via the lateral para-olecranon approach provides favorable midterm outcomes in patients with RA and Larsen grade III-IV disease, preserving triceps function while achieving significant improvements in pain, ROM, strength, and overall elbow function. Complete absence of triceps insufficiency and the favorable outcomes support the present approach as a viable treatment option for appropriately selected patients with RA.

背景:外侧鹰嘴旁入路保留了肱三头肌的完整性,同时为非连接全肘关节置换术(TEA)提供了足够的暴露。然而,其在类风湿关节炎(RA)患者中的有效性尚不清楚。本研究旨在评估经外侧鹰嘴旁入路行非连接TEA治疗RA患者的中期临床和影像学结果,重点关注肱三头肌功能、活动范围(ROM)、力量和并发症。方法:43例肘关节(39例)经外侧鹰嘴旁入路行Kudo假体与非连接TEA术,2例因死亡排除,1例因深部感染取出假体。最终临床队列包括36例患者的40例肘部(27例女性,9例男性;平均年龄64±13岁;平均随访73±33个月)。术前x线片显示12例(30%)肘部为Larsen III级,28例(70%)肘部为IV级。结果包括活跃ROM;手持式测力仪测屈伸强度;手工肌肉测试(MMT);梅奥肘部功能评分;放射评估。结果:所有ROM参数均显著改善:屈曲从121°±17°至137°±6°;扩展范围:-34°±17°至-26°±10°;旋前,64°±16°~ 76°±15°;旋后59°±28°至73°±24°(屈曲和旋前P < 0.001,伸直P = 0.0022,旋后P = 0.0010)。屈伸强度从16±14 N增加到26±20 N (P = 0.0016),从13±12 N增加到23±16 N (P < 0.001)。所有肘部均保持MMT 5级肱三头肌力量。平均MEPS由55±9上升至92±8 (P < 0.001)。在原位植入的40个肘关节中,x线评估显示没有III型或IV型透光。41个肘部的Kaplan-Meier分析显示97.1%的种植体成活率(95%可信区间,81.4%-99.6%)。并发症包括2例术中内上髁骨折(5%)和1例需要取出植入物的深部感染(2%)。未发生三头肌功能不全、半脱位或神经麻痹。结论:对于RA和Larsen III-IV级疾病患者,经外侧鹰口旁入路行非连接TEA可提供良好的中期预后,在保留肱三头肌功能的同时显著改善疼痛、ROM、力量和整体肘关节功能。完全没有肱三头肌功能不全和良好的结果支持目前的方法作为适当选择的RA患者的可行治疗选择。
{"title":"The Lateral Para-olecranon Approach for Unlinked Total Elbow Arthroplasty with the Kudo Prosthesis in Patients with Rheumatoid Arthritis: Midterm Outcomes.","authors":"Shosuke Akita, Naomi Sato, Koji Yachi, Shogo Ikeda, Shunichi Henmi, Takenori Oda","doi":"10.1016/j.jse.2026.02.023","DOIUrl":"https://doi.org/10.1016/j.jse.2026.02.023","url":null,"abstract":"<p><strong>Background: </strong>The lateral para-olecranon approach preserves triceps integrity while providing adequate exposure for unlinked total elbow arthroplasty (TEA). However, its effectiveness in patients with rheumatoid arthritis (RA) remains unclear. This study aimed to evaluate midterm clinical and radiographic outcomes of unlinked TEA performed via the lateral para-olecranon approach in patients with RA, focusing on triceps function, range of motion (ROM), strength, and complications.</p><p><strong>Methods: </strong>Among 43 elbows (39 patients) undergoing unlinked TEA with the Kudo prosthesis via the lateral para-olecranon approach, 2 were excluded because of death and 1 underwent implant removal for deep infection. The final clinical cohort comprised 40 elbows in 36 patients (27 women, 9 men; mean age, 64 ± 13 years; mean follow-up, 73 ± 33 months). Preoperative radiographs showed Larsen grade III in 12 elbows (30%) and grade IV in 28 elbows (70%). Outcomes included active ROM; flexion and extension strength measured by handheld dynamometry; manual muscle testing (MMT); Mayo Elbow Performance Score (MEPS); and radiographic assessment.</p><p><strong>Results: </strong>All ROM parameters improved significantly: flexion, 121° ± 17° to 137° ± 6°; extension, -34° ± 17° to -26° ± 10°; pronation, 64° ± 16° to 76° ± 15°; and supination, 59° ± 28° to 73° ± 24° (P < .001 for flexion and pronation; P = .0022 for extension; P = .0010 for supination). Flexion and extension strength increased from 16 ± 14 to 26 ± 20 N (P = .0016) and from 13 ± 12 to 23 ± 16 N (P < .001). All elbows maintained MMT grade 5 triceps strength. Mean MEPS increased from 55 ± 9 to 92 ± 8 (P < .001). Among 40 elbows with implants in situ, radiographic evaluation revealed no type III or IV lucency. Kaplan-Meier analysis of 41 elbows demonstrated 97.1% implant survival (95% confidence interval, 81.4%-99.6%). Complications included 2 intraoperative medial epicondyle fractures (5%) and 1 deep infection requiring implant removal (2%). No triceps insufficiency, subluxation, or nerve palsy occurred.</p><p><strong>Conclusions: </strong>Unlinked TEA performed via the lateral para-olecranon approach provides favorable midterm outcomes in patients with RA and Larsen grade III-IV disease, preserving triceps function while achieving significant improvements in pain, ROM, strength, and overall elbow function. Complete absence of triceps insufficiency and the favorable outcomes support the present approach as a viable treatment option for appropriately selected patients with RA.</p>","PeriodicalId":50051,"journal":{"name":"Journal of Shoulder and Elbow Surgery","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147464255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Glenohumeral Arthritis Impairs Shoulder Mobility and Promotes Dynamic Compensatory Strategies During Overhead Reach. 肩关节关节炎损害肩关节的活动能力并促进头顶活动时的动态代偿策略。
IF 2.9 2区 医学 Q1 ORTHOPEDICS Pub Date : 2026-03-04 DOI: 10.1016/j.jse.2026.02.019
Nicholas Morriss, Patrick Castle, Dylan N Greif, Joshua Pezzullo, Matthew Ambalavanar, Jordan Manning, Ye Shu, Jacob Earnhart, Gabriel Ramirez, Gregg Nicandri, Sandeep Mannava, Ram Haddas, Ilya Voloshin

Background: Glenohumeral arthritis (GHA) decreases shoulder range of motion, yet the extent of glenohumeral motion loss and accompanying whole-body compensations are not well quantified.

Methods: Eighty-six patients with GHA completed an overhead reach task using both symptomatic and asymptomatic shoulders in a motion-tracking laboratory. Range of motion and peak angles of symptomatic to asymptomatic contralateral shoulders were compared.

Results: The symptomatic shoulder demonstrated 38° less flexion (84° symptomatic vs 122° asymptomatic, p <0.001), 4° less abduction (25° vs 29°, p <0.001), and 22° less internal rotation (21° vs 43°, p <0.001) compared to the asymptomatic shoulder. Patients compensated for these deficits via greater lumbar extension (6° vs 5°, p <0.01), greater lumbar rotation (9° vs 3°, p <0.001), contralateral pelvic rotation (6° vs 2°, p <0.001), reduced cervical flexion (9° vs 18°, p<0.001) with altered lateral bending (7° vs 11°, p<0.001), and greater elbow flexion (26° vs 4°, p 0.001).

Conclusions: GHA is associated with substantial loss of shoulder motion during an overhead reach task that mimics daily activities, which leads to compensatory increases in cervical, lumbar, pelvic, and elbow kinematics.

Clinical relevance: GHA is associated with decreased shoulder motion that results in an increase in compensatory spine motion during daily tasks. This increased compensatory spine motion may place the spine at increased risk for long term pathology.

背景:肩关节关节炎(GHA)会降低肩关节的活动度,但肩关节活动丧失的程度和伴随的全身代偿还没有很好的量化。方法:86例GHA患者在运动跟踪实验室中使用有症状和无症状的肩膀完成了头顶到达任务。比较有症状和无症状对侧肩关节的活动范围和峰值角。结果:有症状的肩部屈曲度减少38°(有症状的84°对无症状的122°)。结论:GHA与模拟日常活动的头顶伸展任务中肩部运动的大量丧失有关,这导致颈椎、腰椎、骨盆和肘关节运动的代偿性增加。临床相关性:GHA与肩部运动减少有关,导致日常工作中代偿性脊柱运动增加。这种增加的代偿性脊柱运动可能增加脊柱长期病理的风险。
{"title":"Glenohumeral Arthritis Impairs Shoulder Mobility and Promotes Dynamic Compensatory Strategies During Overhead Reach.","authors":"Nicholas Morriss, Patrick Castle, Dylan N Greif, Joshua Pezzullo, Matthew Ambalavanar, Jordan Manning, Ye Shu, Jacob Earnhart, Gabriel Ramirez, Gregg Nicandri, Sandeep Mannava, Ram Haddas, Ilya Voloshin","doi":"10.1016/j.jse.2026.02.019","DOIUrl":"https://doi.org/10.1016/j.jse.2026.02.019","url":null,"abstract":"<p><strong>Background: </strong>Glenohumeral arthritis (GHA) decreases shoulder range of motion, yet the extent of glenohumeral motion loss and accompanying whole-body compensations are not well quantified.</p><p><strong>Methods: </strong>Eighty-six patients with GHA completed an overhead reach task using both symptomatic and asymptomatic shoulders in a motion-tracking laboratory. Range of motion and peak angles of symptomatic to asymptomatic contralateral shoulders were compared.</p><p><strong>Results: </strong>The symptomatic shoulder demonstrated 38° less flexion (84° symptomatic vs 122° asymptomatic, p <0.001), 4° less abduction (25° vs 29°, p <0.001), and 22° less internal rotation (21° vs 43°, p <0.001) compared to the asymptomatic shoulder. Patients compensated for these deficits via greater lumbar extension (6° vs 5°, p <0.01), greater lumbar rotation (9° vs 3°, p <0.001), contralateral pelvic rotation (6° vs 2°, p <0.001), reduced cervical flexion (9° vs 18°, p<0.001) with altered lateral bending (7° vs 11°, p<0.001), and greater elbow flexion (26° vs 4°, p 0.001).</p><p><strong>Conclusions: </strong>GHA is associated with substantial loss of shoulder motion during an overhead reach task that mimics daily activities, which leads to compensatory increases in cervical, lumbar, pelvic, and elbow kinematics.</p><p><strong>Clinical relevance: </strong>GHA is associated with decreased shoulder motion that results in an increase in compensatory spine motion during daily tasks. This increased compensatory spine motion may place the spine at increased risk for long term pathology.</p>","PeriodicalId":50051,"journal":{"name":"Journal of Shoulder and Elbow Surgery","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147370552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long-Term Minimum 5-Year Follow-Up 3D CT Evaluation of Bone Graft Status After Latarjet in Patients with No or Minimal Preoperative Glenoid Bone Loss. 术前没有或只有轻微关节骨丢失的患者接受Latarjet后骨移植状态的长期至少5年随访3D CT评估。
IF 2.9 2区 医学 Q1 ORTHOPEDICS Pub Date : 2026-03-04 DOI: 10.1016/j.jse.2026.02.020
Lionel Neyton, Yash Sewpaul, Louis Lajoinie, Lisa Peduzzi, Joris Tiercelin, Xavier Ohl

Purpose: The purpose of this study was to evaluate the Latarjet coracoid graft status using CT at minimum 5-year follow-up in a population with less than 5% glenoid bone loss preoperatively. We hypothesized that complete graft lysis would occur in accordance with Wolff's law.

Methods: This retrospective multicenter study included patients treated with an open Latarjet procedure across eight centers who had less than 5% preoperative glenoid bone loss and available preoperative and follow-up CT scans. Glenoid bone defects were measured using the best-fit circle method on 2D CT. The preoperative glenoid articular surface was compared with the follow-up useful glenoid surface. Three-dimensional CT reconstructions with humeral head subtraction were analyzed to assess graft consolidation, resorption patterns, and screw coverage in sagittal, coronal, and anterior planes.

Results: Thirty-four patients met the inclusion criteria, with a mean follow-up of 98.7 ± 32 months (range 60-172). Four patients experienced graft failure (1 fracture, 3 non-unions), resulting in a graft consolidation rate of 97%. Among the 30 patients with consolidated grafts, the mean useful glenoid surface increased by 1.28 ± 0.97 cm2 (p < 0.001), corresponding to a mean glenoid articular surface augmentation of 20.9 ± 23.9%. Three-dimensional CT reconstructions were available in 24 cases and demonstrated consistent graft resorption, predominantly affecting the superomedial aspect of the graft, with partial exposure of the superior screw in most cases.

Conclusion: At a mean follow-up of 8 years, the coracoid graft remained present in 97% of cases, even in patients with minimal preoperative glenoid bone loss (<5%). 2D CT showed a mean glenoid surface augmentation of 20.9%, while 3D analysis revealed consistent superomedial resorption. These findings demonstrate graft consolidation with a low complication rate, suggesting that the Latarjet procedure can be effective in this population.

Level of evidence: Level IV, Case Series, Treatment Study.

目的:本研究的目的是在术前关节盂骨丢失小于5%的人群中,通过CT随访评估Latarjet喙骨移植的状态。我们假设根据Wolff定律,移植物会发生完全溶解。方法:这项回顾性多中心研究纳入了8个中心接受开放式Latarjet手术的患者,术前关节盂骨丢失小于5%,术前和随访CT扫描可用。在二维CT上采用最佳拟合圆法测量关节盂骨缺损。术前盂关节面与随访有用盂关节面比较。分析肱骨头减影后的三维CT重建,以评估移植物巩固、吸收模式以及矢状面、冠状面和前平面的螺钉覆盖情况。结果:34例患者符合纳入标准,平均随访时间98.7±32个月(60 ~ 172个月)。4例患者发生植骨失败(1例骨折,3例不愈合),植骨巩固率为97%。在30例经巩固移植的患者中,平均有效关节面增加1.28±0.97 cm2 (p < 0.001),对应于平均关节面增加20.9±23.9%。24例三维CT重建显示移植物吸收一致,主要影响移植物的上内侧,大多数情况下上部螺钉部分暴露。结论:在平均8年的随访中,97%的病例仍然存在喙骨移植物,即使在术前有最小的盂骨丢失的患者中也是如此(证据级别:IV级,病例系列,治疗研究)。
{"title":"Long-Term Minimum 5-Year Follow-Up 3D CT Evaluation of Bone Graft Status After Latarjet in Patients with No or Minimal Preoperative Glenoid Bone Loss.","authors":"Lionel Neyton, Yash Sewpaul, Louis Lajoinie, Lisa Peduzzi, Joris Tiercelin, Xavier Ohl","doi":"10.1016/j.jse.2026.02.020","DOIUrl":"https://doi.org/10.1016/j.jse.2026.02.020","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to evaluate the Latarjet coracoid graft status using CT at minimum 5-year follow-up in a population with less than 5% glenoid bone loss preoperatively. We hypothesized that complete graft lysis would occur in accordance with Wolff's law.</p><p><strong>Methods: </strong>This retrospective multicenter study included patients treated with an open Latarjet procedure across eight centers who had less than 5% preoperative glenoid bone loss and available preoperative and follow-up CT scans. Glenoid bone defects were measured using the best-fit circle method on 2D CT. The preoperative glenoid articular surface was compared with the follow-up useful glenoid surface. Three-dimensional CT reconstructions with humeral head subtraction were analyzed to assess graft consolidation, resorption patterns, and screw coverage in sagittal, coronal, and anterior planes.</p><p><strong>Results: </strong>Thirty-four patients met the inclusion criteria, with a mean follow-up of 98.7 ± 32 months (range 60-172). Four patients experienced graft failure (1 fracture, 3 non-unions), resulting in a graft consolidation rate of 97%. Among the 30 patients with consolidated grafts, the mean useful glenoid surface increased by 1.28 ± 0.97 cm<sup>2</sup> (p < 0.001), corresponding to a mean glenoid articular surface augmentation of 20.9 ± 23.9%. Three-dimensional CT reconstructions were available in 24 cases and demonstrated consistent graft resorption, predominantly affecting the superomedial aspect of the graft, with partial exposure of the superior screw in most cases.</p><p><strong>Conclusion: </strong>At a mean follow-up of 8 years, the coracoid graft remained present in 97% of cases, even in patients with minimal preoperative glenoid bone loss (<5%). 2D CT showed a mean glenoid surface augmentation of 20.9%, while 3D analysis revealed consistent superomedial resorption. These findings demonstrate graft consolidation with a low complication rate, suggesting that the Latarjet procedure can be effective in this population.</p><p><strong>Level of evidence: </strong>Level IV, Case Series, Treatment Study.</p>","PeriodicalId":50051,"journal":{"name":"Journal of Shoulder and Elbow Surgery","volume":" ","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147370582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Eccentric mechanical stimulation promotes rotator cuff healing by regulating macrophage polarization in a murine model 在小鼠模型中,偏心机械刺激通过调节巨噬细胞极化促进肩袖愈合。
IF 2.9 2区 医学 Q1 ORTHOPEDICS Pub Date : 2026-03-01 Epub Date: 2025-08-22 DOI: 10.1016/j.jse.2025.07.008
Yundong Peng PhD , Luyu Diao PhD , Fengxing Li PhD , Jieping Wang PhD , Yonghong Yu MSc , Shaohui Jia PhD , Cheng Zheng PhD, MD

Background

Eccentric mechanical stimulation (EMS) has been proposed as a potential therapy for tendon-bone injuries. Macrophages, as key immune cells, may play a significant role in promoting tendon-bone injury healing through mechanical stimulation, because of their polarization. This study aims to investigate the role of macrophages in rotator cuff injury repair promoted by EMS.

Methods

A total of 96 male C57BL/6 mice were used to establish a rotator cuff injury repair model and were randomly divided into 4 groups: Control, EMS, control + clodronate liposomes, and EMS + clodronate liposomes. Specimens were collected at 2 and 4 weeks postoperatively for histologic, radiologic, immunohistochemical, and biomechanical analyses.

Results

At 2 weeks postoperatively, the EMS group exhibited a thicker fibrocartilage layer and increased expression of M2 macrophages compared with other groups. At 4 weeks, histologic analysis revealed higher fibrocartilage and proteoglycan content in the EMS group, with increased local expression of M2 macrophages and reduced expression of M1 macrophages. Micro–computed tomography results showed superior bone volume–total volume fraction, trabecular bone number, and trabecular bone thickness in the EMS group. Biomechanical testing indicated higher failure load and ultimate strength in the EMS group. The positive effects of mechanical stimulation were significantly diminished after macrophage depletion using clodronate liposomes.

Conclusion

Macrophages may play a crucial role in the repair of rotator cuff injuries promoted by EMS. The therapeutic benefits are partly attributed to the regulation of macrophage function, with EMS reducing M1 macrophage expression and enhancing M2 macrophage polarization. This promotes the healing of rotator cuff tendon–bone injuries and suggests that targeting macrophage polarization may have positive effects on tendon-bone interface injury recovery.
背景:偏心机械刺激(EMS)已被提出作为一种潜在的治疗肌腱-骨损伤的方法。巨噬细胞作为关键的免疫细胞,由于其极化特性,可能在通过机械刺激促进肌腱-骨损伤愈合中发挥重要作用。本研究旨在探讨巨噬细胞在EMS促进肩袖损伤修复中的作用。方法:选取96只雄性C57BL/6小鼠建立肩袖损伤修复模型,随机分为对照组、EMS组、对照组+氯膦酸盐脂质体(Con-CL)组和EMS- cl组。术后2周和4周采集标本进行组织学、放射学、免疫组织化学和生物力学分析。结果:术后2周,EMS组纤维软骨层较其他组增厚,M2巨噬细胞表达增加。4周时,组织学分析显示,EMS组纤维软骨和蛋白多糖含量较高,局部M2巨噬细胞表达增加,M1巨噬细胞表达减少。显微ct结果显示骨体积分数(BV/TV)、骨小梁数(Tb。N), EMS组小梁厚度(Tb.Th)。生物力学测试表明,EMS组的破坏负荷(FL)和极限强度(US)更高。使用CL清除巨噬细胞后,机械刺激的积极作用明显减弱。结论:巨噬细胞可能在偏心机械刺激引起的肩袖损伤修复中起重要作用。治疗效果部分归因于巨噬细胞功能的调节,偏心机械刺激降低M1巨噬细胞表达,增强M2巨噬细胞极化。这促进了肩袖肌腱-骨损伤的愈合,提示靶向巨噬细胞极化可能对肩袖修复中肌腱-骨界面损伤的恢复愈合具有积极作用。证据水平:基础科学研究;体内动物模型。
{"title":"Eccentric mechanical stimulation promotes rotator cuff healing by regulating macrophage polarization in a murine model","authors":"Yundong Peng PhD ,&nbsp;Luyu Diao PhD ,&nbsp;Fengxing Li PhD ,&nbsp;Jieping Wang PhD ,&nbsp;Yonghong Yu MSc ,&nbsp;Shaohui Jia PhD ,&nbsp;Cheng Zheng PhD, MD","doi":"10.1016/j.jse.2025.07.008","DOIUrl":"10.1016/j.jse.2025.07.008","url":null,"abstract":"<div><h3>Background</h3><div>Eccentric mechanical stimulation (EMS) has been proposed as a potential therapy for tendon-bone injuries. Macrophages, as key immune cells, may play a significant role in promoting tendon-bone injury healing through mechanical stimulation, because of their polarization. This study aims to investigate the role of macrophages in rotator cuff injury repair promoted by EMS.</div></div><div><h3>Methods</h3><div>A total of 96 male C57BL/6 mice were used to establish a rotator cuff injury repair model and were randomly divided into 4 groups: Control, EMS, control + clodronate liposomes, and EMS + clodronate liposomes. Specimens were collected at 2 and 4 weeks postoperatively for histologic, radiologic, immunohistochemical, and biomechanical analyses.</div></div><div><h3>Results</h3><div>At 2 weeks postoperatively, the EMS group exhibited a thicker fibrocartilage layer and increased expression of M2 macrophages compared with other groups. At 4 weeks, histologic analysis revealed higher fibrocartilage and proteoglycan content in the EMS group, with increased local expression of M2 macrophages and reduced expression of M1 macrophages. Micro–computed tomography results showed superior bone volume–total volume fraction, trabecular bone number, and trabecular bone thickness in the EMS group. Biomechanical testing indicated higher failure load and ultimate strength in the EMS group. The positive effects of mechanical stimulation were significantly diminished after macrophage depletion using clodronate liposomes.</div></div><div><h3>Conclusion</h3><div>Macrophages may play a crucial role in the repair of rotator cuff injuries promoted by EMS. The therapeutic benefits are partly attributed to the regulation of macrophage function, with EMS reducing M1 macrophage expression and enhancing M2 macrophage polarization. This promotes the healing of rotator cuff tendon–bone injuries and suggests that targeting macrophage polarization may have positive effects on tendon-bone interface injury recovery.</div></div>","PeriodicalId":50051,"journal":{"name":"Journal of Shoulder and Elbow Surgery","volume":"35 3","pages":"Pages 832-840"},"PeriodicalIF":2.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144976683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of time from injury to surgery on surgical technique and complication rate in distal biceps tendon repair 损伤至手术时间对肱二头远端肌腱修复术技术及并发症发生率的影响。
IF 2.9 2区 医学 Q1 ORTHOPEDICS Pub Date : 2026-03-01 Epub Date: 2025-09-01 DOI: 10.1016/j.jse.2025.07.027
Laura J. Morrison MD, MSc , Chloe Elliott BS , Bayan Ghalimah MD , Eric C. Sayre PhD , Neil J. White MD

Background

Surgical treatment options for distal biceps tendon ruptures vary based on time from injury to surgery. While direct repair (DR) is preferred for acute injuries, high flexion angle (HFA) repair and allograft reconstruction (AR) are alternatives for chronic cases. This study examines the relationship between time to surgery, surgical technique selection, and complication rates.

Methods

A retrospective chart review was conducted on patients treated surgically for distal biceps tendon ruptures at a single center from January 2012 to June 2023. Cases were identified through electronic medical records and included patients aged ≥ 18 years with unilateral ruptures. Demographics, time to surgery, surgical techniques (DR, HFA repair, and AR), and complications were recorded. Descriptive statistics and multinomial logistic regression were used to assess the association between time to surgery and surgical technique.

Results

A total of 373 patients were included, with 90% undergoing DR (n = 334), 6% HFA repair (n = 22), and 5% AR (n = 17). The mean (standard deviation) time from injury to surgery was 16 (± 30) days for DR, 82 (± 162) days for HFA repair, and 274 (± 455) days for AR. Surgical technique selection was significantly associated with time to surgery (Kruskal Wallis P < .001), with DR favored in acute cases and HFA repair/AR in chronic presentations. The inflection point for equal probabilities of DR, HFA repair, and AR occurred at 25-27 weeks postinjury. The overall complication rate was 12% (n = 45), with nerve injuries being the most common (7%, n = 25).

Conclusion

Timing significantly impacts surgical technique selection in distal biceps tendon ruptures. DR remains the standard for acute injuries, while HFA repair and AR are viable options for chronic cases. The multinomial probability graphic can be used to educate and counsel patients on surgical decision-making for chronic distal biceps ruptures.
背景:肱二头肌远端肌腱断裂的手术治疗选择取决于从受伤到手术的时间。而直接修复(DR)是首选急性损伤,高屈曲角修复(HFA)和同种异体移植物重建(AR)是替代慢性病例。本研究探讨手术时间、手术技术选择和并发症发生率之间的关系。方法:回顾性分析2012年1月至2023年6月单中心手术治疗肱二头肌远端肌腱断裂的病例。病例通过电子病历确定,包括≥18岁的单侧破裂患者。记录人口统计学、手术时间、手术技术(DR、HFA、AR)和并发症。使用描述性统计和多项逻辑回归来评估手术时间与手术技术之间的关系。结果:共纳入373例患者,其中90%接受DR (n=334), 6%接受HFA (n=22), 5%接受AR (n=17)。从损伤到手术的平均(标准差)时间DR为16(±30)天,HFA为82(±162)天,AR为274(±455)天。手术技术选择与手术时间显著相关(Kruskal Wallis p)结论:时间选择显著影响远端二头肌肌腱断裂的手术技术选择。DR仍然是急性损伤的标准,而HFA和AR是慢性病例的可行选择。多项概率图(图2)可用于教育和指导慢性二头肌远端骨折患者的手术决策。
{"title":"Effect of time from injury to surgery on surgical technique and complication rate in distal biceps tendon repair","authors":"Laura J. Morrison MD, MSc ,&nbsp;Chloe Elliott BS ,&nbsp;Bayan Ghalimah MD ,&nbsp;Eric C. Sayre PhD ,&nbsp;Neil J. White MD","doi":"10.1016/j.jse.2025.07.027","DOIUrl":"10.1016/j.jse.2025.07.027","url":null,"abstract":"<div><h3>Background</h3><div>Surgical treatment options for distal biceps tendon ruptures vary based on time from injury to surgery. While direct repair (DR) is preferred for acute injuries, high flexion angle (HFA) repair and allograft reconstruction (AR) are alternatives for chronic cases. This study examines the relationship between time to surgery, surgical technique selection, and complication rates.</div></div><div><h3>Methods</h3><div>A retrospective chart review was conducted on patients treated surgically for distal biceps tendon ruptures at a single center from January 2012 to June 2023. Cases were identified through electronic medical records and included patients aged ≥ 18 years with unilateral ruptures. Demographics, time to surgery, surgical techniques (DR, HFA repair, and AR), and complications were recorded. Descriptive statistics and multinomial logistic regression were used to assess the association between time to surgery and surgical technique.</div></div><div><h3>Results</h3><div>A total of 373 patients were included, with 90% undergoing DR (n = 334), 6% HFA repair (n = 22), and 5% AR (n = 17). The mean (standard deviation) time from injury to surgery was 16 (± 30) days for DR, 82 (± 162) days for HFA repair, and 274 (± 455) days for AR. Surgical technique selection was significantly associated with time to surgery (Kruskal Wallis <em>P</em> &lt; .001), with DR favored in acute cases and HFA repair/AR in chronic presentations. The inflection point for equal probabilities of DR, HFA repair, and AR occurred at 25-27 weeks postinjury. The overall complication rate was 12% (n = 45), with nerve injuries being the most common (7%, n = 25).</div></div><div><h3>Conclusion</h3><div>Timing significantly impacts surgical technique selection in distal biceps tendon ruptures. DR remains the standard for acute injuries, while HFA repair and AR are viable options for chronic cases. The multinomial probability graphic can be used to educate and counsel patients on surgical decision-making for chronic distal biceps ruptures.</div></div>","PeriodicalId":50051,"journal":{"name":"Journal of Shoulder and Elbow Surgery","volume":"35 3","pages":"Pages 826-831"},"PeriodicalIF":2.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144994275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of Shoulder and Elbow Surgery
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1