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The role and outcomes of music therapy during pregnancy: a systematic review of randomized controlled trials. 孕期音乐治疗的作用和结果:随机对照试验的系统回顾。
IF 3.1 3区 医学 Q1 Medicine Pub Date : 2024-12-01 Epub Date: 2023-12-26 DOI: 10.1080/0167482X.2023.2291635
Chao Ji, Jing Zhao, Qiaole Nie, Shuo Wang

Introduction: The abundant functions of music and its effects on human's mental and physical health have been verified since ancient times, but rarely received attention as an alternative obstetric intervention.

Objective: This study aims to investigate the benefits of music therapy on prenatal and delivery experiences of pregnant women.

Method: A systematic search for articles was conducted in electronic databases including CINAHL, Web of Science, PubMed/Medline, and CNKI. A total of 240 articles were identified, and 17 studies were selected for this review. The extracted data included author, year, location, sample size, intervention phase, type of music, music therapy strategy, measuring instruments, and results. The data were organized chronologically based on the publication year of each study.

Result: The articles indicated that music therapy has advantages in reducing pain during childbirth, lowering anxiety and stress levels in mothers, improving sleep quality, and increasing fetal movements, basal fetal heart rate, and accelerations.

Conclusion: Based on the findings, it can be concluded that music therapy is an effective approach to enhance the experience of pregnant women during pregnancy and delivery. Therefore, its implementation in obstetrical clinical practice is highly recommended.

简介:音乐的丰富功能及其对人类身心健康的影响自古以来就已得到证实,但作为一种可供选择的产科干预措施却很少受到关注:本研究旨在探讨音乐疗法对孕妇产前和分娩体验的益处:方法:在 CINAHL、Web of Science、PubMed/Medline 和 CNKI 等电子数据库中对文章进行了系统检索。共检索到 240 篇文章,其中 17 项研究被选入本综述。提取的数据包括作者、年份、地点、样本量、干预阶段、音乐类型、音乐治疗策略、测量工具和结果。数据根据每项研究的发表年份按时间顺序排列:结果:文章表明,音乐疗法在减轻分娩疼痛、降低母亲焦虑和压力水平、改善睡眠质量、增加胎动、基础胎心率和加速度方面具有优势:根据研究结果,可以得出结论:音乐疗法是改善孕妇妊娠和分娩体验的有效方法。因此,强烈建议在产科临床实践中实施音乐疗法。
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引用次数: 0
Predictors for cannabis cessation during pregnancy: a 10-year cohort study. 孕期戒除大麻的预测因素:一项为期 10 年的队列研究。
IF 3.1 3区 医学 Q1 Medicine Pub Date : 2024-12-01 Epub Date: 2024-02-24 DOI: 10.1080/0167482X.2024.2319290
Maia Brik, Miguel Sandonis, Carmen Cabeza Oliver, Joaquín Temprado, Alina Hernández Fleury, Elena Sánchez Echevarria, Elena Carreras

The aim of this study is to determine factors associated with cannabis discontinuation, to assess the impact of mental health and addiction interventions on cannabis discontinuation during pregnancy and to investigate the neonatal impact of cannabis discontinuation. This is a 10-year cohort study in a tertiary hospital in Barcelona, Spain, including women with self-reported cannabis use during pregnancy. Main outcome was cannabis discontinuation based on biological sample testing. Secondary outcomes were neonatal intensive care unit (NICU) admission, preterm birth, birth weight and bottle-feeding. When cannabis use was detected during pregnancy, 32 out of 81 (38.3%) discontinued cannabis during pregnancy vs. four out of 61 (6.6%) when detected at birth (p < .001). Multivariate binary logistic regression showed that null parity (OR: 6.95, p = .011), detection of cannabis use during pregnancy (OR: 5.35, p = .018) and early detection and referral to mental health care for counseling on cannabis cessation and interventions on the first trimester (OR: 25.46, p < .001) increased cannabis discontinuation. Risk for preterm birth <37 weeks (11.4% vs. 30.8%) and NICU admission (25.7% vs. 54.2%) were lower when discontinuation. Early detection of cannabis use during pregnancy, cessation counseling with mental health interventions, and null parity are predictors for cannabis discontinuation during pregnancy.

本研究旨在确定与停止吸食大麻有关的因素,评估精神健康和成瘾干预对孕期停止吸食大麻的影响,并调查停止吸食大麻对新生儿的影响。这是一项在西班牙巴塞罗那一家三甲医院进行的为期 10 年的队列研究,研究对象包括自我报告在怀孕期间吸食大麻的妇女。主要结果是根据生物样本检测结果确定是否停止使用大麻。次要结果是入住新生儿重症监护室(NICU)、早产、出生体重和奶瓶喂养。在怀孕期间检测到使用大麻时,81 名孕妇中有 32 人(38.3%)在怀孕期间停止使用大麻,而在出生时检测到使用大麻时,61 名孕妇中有 4 人(6.6%)在出生时停止使用大麻(P = .011);在怀孕期间检测到使用大麻(OR:5.35,P = .018);在怀孕头三个月及早检测到并转介到心理保健机构接受戒大麻咨询和干预(OR:25.46,P = .018)。
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引用次数: 0
Decision-making in case of an unintended pregnancy: an overview of what is known about this complex process. 意外怀孕时的决策:对这一复杂过程的了解综述。
IF 3.1 3区 医学 Q1 Medicine Pub Date : 2024-12-01 Epub Date: 2024-03-12 DOI: 10.1080/0167482X.2024.2321461
Eline W Dalmijn, Merel A Visse, Inge van Nistelrooij

Introduction: Unintended pregnancies are a worldwide health issue, faced each year by one in 16 people, and experienced in various ways. In this study we focus on unintended pregnancies that are, at some point, experienced as unwanted because they present the pregnant person with a decision to continue or terminate the pregnancy. The aim of this study is to learn more about the decision-making process, as there is a lack of insights into how people with an unintended pregnancy reach a decision. This is caused by 1) assumptions of rationality in reproductive autonomy and decision-making, 2) the focus on pregnancy outcomes, e.g. decision-certainty and reasons and, 3) the focus on abortion in existing research, excluding 40% of people with an unintended pregnancy who continue the pregnancy. Method: We conducted a narrative literature review to examine what is known about the decision-making process and aim to provide a deeper understanding of how persons with unintended pregnancy come to a decision.Results: Our analysis demonstrates that the decision-making process regarding unintended pregnancy consists of navigating entangled layers, rather than weighing separable elements or factors. The layers that are navigated are both internal and external to the person, in which a 'sense of knowing' is essential in the decision-making process. Conclusion: The layers involved and complexity of the decision-making regarding unintended pregnancy show that a rational decision-making frame is inadequate and a more holistic frame is needed to capture this dynamic and personal experience.

导言:意外怀孕是一个世界性的健康问题,每年每 16 人中就有 1 人面临意外怀孕,而且意外怀孕的方式多种多样。在本研究中,我们将重点放在意外怀孕上,这些怀孕在某种程度上被认为是不想要的,因为怀孕者需要做出继续妊娠或终止妊娠的决定。本研究的目的是进一步了解决策过程,因为我们对意外怀孕者如何做出决定缺乏深入了解。造成这种情况的原因有:1)生殖自主和决策的理性假设;2)关注妊娠结果,如决策的确定性和原因;3)现有研究只关注人工流产,将继续妊娠的 40% 意外怀孕者排除在外。研究方法我们对文献进行了叙事性回顾,研究了有关决策过程的已知信息,旨在更深入地了解意外怀孕者是如何做出决定的:我们的分析表明,有关意外怀孕的决策过程是在纠缠不清的层次中进行的,而不是权衡可分离的要素或因素。在决策过程中,"认知感 "是必不可少的。结论意外怀孕决策所涉及的层次和复杂性表明,理性的决策框架是不够的,需要一个更全面的框架来捕捉这种动态的个人经历。
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引用次数: 0
Clinical characteristics of female long COVID patients with menstrual symptoms: a retrospective study from a Japanese outpatient clinic. 有月经症状的女性长COVID患者的临床特征:一项来自日本门诊的回顾性研究。
IF 3.1 3区 医学 Q1 Medicine Pub Date : 2024-12-01 Epub Date: 2024-01-25 DOI: 10.1080/0167482X.2024.2305899
Yasue Sakurada, Yui Matsuda, Kanon Motohashi, Toru Hasegawa, Yuki Otsuka, Yasuhiro Nakano, Kazuki Tokumasu, Koichiro Yamamoto, Naruhiko Sunada, Hiroyuki Honda, Hideharu Hagiya, Keigo Ueda, Fumio Otsuka

Purpose: To elucidate the impact of long COVID on menstruation and mental health, medical records of patients with long COVID were evaluated.

Methods: Symptoms of long COVID, QOL, mental health, and related endocrine data were compared between two groups with and without menstrual disturbances.

Results: Of 349 female patients who visited our clinic between February 2021 and March 2023, 223 patients with long COVID (aged 18-50 years) were included. Forty-four (19.7%) of the patients had menstrual symptoms associated with long COVID. The patients with menstrual symptoms were older than those without menstrual symptoms (42.5 vs. 38 years). The percentage of patients with menstrual symptoms was higher during the Omicron phase (24%) than during the Preceding (13%) and Delta (12%) phases. Cycle irregularity was the most frequent (in 63.6% of the patients), followed by severe pain (25%), heavy bleeding (20.5%), perimenopausal symptoms (18.2%), and premenstrual syndrome (15.9%). Fatigue and depression were the most frequent complications. Scores for fatigue and for QOL were significantly worse in long COVID patients with menstrual symptoms. Results of endocrine examinations showed significantly increased cortisol levels in patients with menstrual complaints.

Conclusion: Long COVID has an impact on menstrual conditions and on QOL related to menstrual conditions.

目的:为了阐明长期月经失调对月经和心理健康的影响,我们对长期月经失调患者的病历进行了评估:方法:比较有月经紊乱和无月经紊乱两组患者的长期COVID症状、QOL、心理健康和相关内分泌数据:结果:在 2021 年 2 月至 2023 年 3 月期间就诊的 349 名女性患者中,有 223 名患者患有长 COVID(18-50 岁)。其中 44 名患者(19.7%)有与长 COVID 相关的月经症状。有月经症状的患者年龄比无月经症状的患者大(42.5 岁对 38 岁)。有月经症状的患者在 Omicron 期(24%)的比例高于 Preceding 期(13%)和 Delta 期(12%)。最常见的症状是月经周期不规律(占 63.6%),其次是剧烈疼痛(25%)、大量出血(20.5%)、围绝经期症状(18.2%)和经前综合征(15.9%)。疲劳和抑郁是最常见的并发症。有月经症状的长期 COVID 患者的疲劳和 QOL 评分明显较差。内分泌检查结果显示,月经不调患者的皮质醇水平明显升高:结论:长期 COVID 会影响月经状况以及与月经状况相关的 QOL。
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引用次数: 0
Validation of the Birth Beliefs Scale for maternity care professionals in The Netherlands. 为荷兰孕产妇护理专业人员验证分娩信念量表。
IF 2.1 3区 医学 Q2 OBSTETRICS & GYNECOLOGY Pub Date : 2024-12-01 Epub Date: 2024-08-21 DOI: 10.1080/0167482X.2024.2392160
Dirkje C Zondag, Tamar M van Haaren-Ten Haken, Pien M Offerhaus, Eveline Mestdagh, Hubertina C J Scheepers, Marianne J Nieuwenhuijze

Objectives: To validate the Birth Beliefs Scale (BBS) for maternity care professionals by testing: (1) content validity; (2) internal reliability; (3) known-group discriminant validity; and examine potential relationships between regions and birth beliefs.

Methods: First, content validity was tested. Before distribution of the questionnaire among maternity care professionals of six maternity care networks (MCNs), adjustments in the statements were made whenever content validity was too low. Data were collected from November 2022 to March 2023. Statistical analysis was performed using Cronbach's alpha, ANOVA and regression analysis.

Results: Based on the content validity-test, item 6 of the questionnaire was adjusted before distribution. In total, 199 maternity care professionals completed the questionnaire. A good internal reliability of the BBS was found. There was a significant difference between the different disciplines for the BBS-Med subscale (p < .001), and the BBS-Nat subscale (p < .001). For the BBS-Nat subscale, the factors work experience and MCN were significant in the regression analysis, with interaction on the association between BBS-Nat and discipline.

Conclusions: The BBS is a valid instrument to measure birth beliefs among maternity care professionals. The BBS can help to create awareness within professionals of their beliefs and may help to explain practice variation in childbirth.

目的通过测试:(1) 内容效度;(2) 内部信度;(3) 已知群体判别效度;以及研究地区与分娩信念之间的潜在关系,验证产科护理专业人员的分娩信念量表(BBS):首先,对内容效度进行测试。在向 6 个孕产妇护理网络(MCNs)的孕产妇护理专业人员发放问卷之前,对内容效度过低的语句进行了调整。数据收集时间为 2022 年 11 月至 2023 年 3 月。采用Cronbach's alpha、方差分析和回归分析进行统计分析:根据内容效度测试结果,问卷第 6 项在发放前进行了调整。共有 199 名产妇护理专业人员填写了问卷。BBS 的内部信度良好。在 BBS-医疗分量表中,不同学科之间存在明显差异(p p 结论:BBS-医疗分量表是一个有效的工具,可用于产妇护理专业人员的健康管理:BBS 是测量孕产妇护理专业人员分娩信念的有效工具。BBS 有助于提高专业人员对其信念的认识,并有助于解释分娩实践中的差异。
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引用次数: 0
Mental illness and sleep disorders among women with gynecological problems. 患有妇科疾病的妇女的精神疾病和睡眠障碍。
IF 3.1 3区 医学 Q1 Medicine Pub Date : 2024-12-01 Epub Date: 2024-06-01 DOI: 10.1080/0167482X.2024.2354330
Ray M Merrill, Dajeong Song

This retrospective cohort study identifies differences between rates of selected mental illnesses and sleep disorders according to eight gynecological problems. Analyses utilize medical claims data for adult employees of a large corporation during 2017-2021. Women with a gynecological problem (most notably pain, endometriosis, pelvic inflammation and bleeding) are significantly more likely to experience mental illness. Several gynecological problems are also significantly associated with sleep disorders. Women with a gynecological problem (vs. none) are 50% more likely to have a mental health problem and 44% more likely to have a sleep disorder after adjusting for age, marital status, dependent children and year. The largest differences between higher (%) mental illness and sleep disorders appear for hyperplasia (6% vs. 45%), cancer (11% vs. 68%), pelvic inflammation (46% vs. 79%) and pain (79% vs. 43%), respectively. On the other hand, the rate of having one or more gynecological problems ranges from 7.1% for women with no mental illness or sleep disorder to 20.6% for women with schizophrenia. Understanding the association between gynecological problems, mental illness and sleep disorders can help clinicians more effectively identify and treat patients.

这项回顾性队列研究根据八种妇科疾病确定了特定精神疾病和睡眠障碍发病率之间的差异。分析利用了一家大型企业成年员工在 2017-2021 年期间的医疗索赔数据。患有妇科疾病(最明显的是疼痛、子宫内膜异位症、盆腔炎和出血)的女性患精神疾病的几率明显更高。几种妇科疾病与睡眠障碍也有明显关联。在对年龄、婚姻状况、受抚养子女和年份进行调整后,有妇科疾病的女性(与没有妇科疾病的女性相比)出现精神健康问题的几率要高出 50%,出现睡眠障碍的几率要高出 44%。患有精神疾病和睡眠障碍的比例(%)差异最大的分别是增生(6% 对 45%)、癌症(11% 对 68%)、盆腔炎(46% 对 79%)和疼痛(79% 对 43%)。另一方面,患有一种或多种妇科疾病的比例从没有精神疾病或睡眠障碍的妇女的 7.1%到患有精神分裂症的妇女的 20.6%不等。了解妇科问题、精神疾病和睡眠障碍之间的关联有助于临床医生更有效地识别和治疗患者。
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引用次数: 0
Investigating socioeconomic disparities of Kangaroo mother care on preterm infant health outcomes. 调查袋鼠妈妈护理对早产儿健康影响的社会经济差异。
IF 3.1 3区 医学 Q1 Medicine Pub Date : 2024-12-01 Epub Date: 2024-01-08 DOI: 10.1080/0167482X.2023.2299982
Muhammad Muneeb Hassan, Muhammad Ameeq, M H Tahir, Sidra Naz, Laraib Fatima, Alpha Kargbo

Several studies have been conducted to examine the complicated relationships between various factors that influence Kangaroo mother care (KMC) for preterm infants. However, the extended socio-economic model has not been seen in any of the previous studies that looked into the factors related to KMC and how it affects the health outcomes of babies born before in our study population. This study examines the various dimensions of KMC implementation and its influence on the health outcomes of premature infants. The current cross-sectional study was carried out in South Punjab, Pakistan, covering both private and public KMC units in obstetrics and gynecology departments. The study included a sample size of 719 patients and was conducted during a period covering 21 September 2022 to 14 October 2023. Multinomial logistic regression analysis is employed to ascertain the factors by using SPSS-26 (SPSS Inc., Chicago, IL). The use of folic acid (OR: 1.44; 95% CI: 0.87-3.11) and factor anemia (OR: 8.82; 95% CI: 1.69-14.59) no significantly correlated with better health outcomes, while environmental toxin exposure had a negative impact (OR: 0.90). The findings underscore the need for comprehensive interventions and policies to bridge socioeconomic gaps, ensuring all preterm infants benefit from KMC.

已有多项研究探讨了影响早产儿袋鼠妈妈护理(Kangaroo Mother Care,KMC)的各种因素之间的复杂关系。然而,在我们的研究人群中,以前的任何一项研究都没有发现扩展的社会经济模型,这些研究探讨了与袋鼠妈妈护理相关的因素,以及袋鼠妈妈护理如何影响早产儿的健康状况。本研究探讨了实施 KMC 的各个层面及其对早产儿健康结果的影响。本横断面研究在巴基斯坦南旁遮普省进行,涵盖了妇产科的私立和公立 KMC 单位。研究的样本量为 719 名患者,研究时间跨度为 2022 年 9 月 21 日至 2023 年 10 月 14 日。研究使用 SPSS-26 (SPSS Inc., Chicago, IL) 进行多项式逻辑回归分析,以确定影响因素。叶酸的使用(OR:1.44;95% CI:0.87-3.11)和贫血因素(OR:8.82;95% CI:1.69-14.59)与更好的健康结果无显著相关性,而环境毒素暴露则有负面影响(OR:0.90)。研究结果强调,有必要采取全面的干预措施和政策来缩小社会经济差距,确保所有早产儿都能从 KMC 中受益。
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引用次数: 0
Assessment of factors related to poly cystic ovarian syndrome - A comparative and correlational study. 多囊卵巢综合征相关因素评估--一项比较和相关研究。
IF 3.1 3区 医学 Q1 Medicine Pub Date : 2024-12-01 Epub Date: 2023-12-27 DOI: 10.1080/0167482X.2023.2297166
Aparna Eledath Kolasseri, Anjana Eledath Kolasseri, Jayanthi Sivaraman, Tamizhselvi Ramasamy

Polycystic ovarian syndrome (PCOS) is a common endocrine disorder that primarily affects women of reproductive age. It is particularly prevalent among adolescent females who receive an insufficient diagnosis despite having potentially adverse consequences. The use of PCOS screening questionnaires has the potential to aid in the early detection of symptoms. The goal of this study is to observe if a self-administered questionnaire may be useful for a clear cognizance of the associated conditions like mental stress and menstrual characteristics correlated to polycystic ovary syndrome. In this study, we selected women within an age group of 17-40 with and without PCOS based on the modified Rotterdam criteria to fill out a self-administrated questionnaire based on the signs and symptoms of PCOS majorly focusing on mental stress and menstrual characteristics. SPSS software, univariate analyses were employed to elucidate the associations among the components of PCOS, demographic factors, and lifestyle characteristics, hence providing insights into the interrelationships among those variables. 64 women with PCOS and 141 women without PCOS participated in the present study. The present study revealed PCOS is greatly influenced by age at menarche (p-value= .043), typical cycle length (p-value = .000) mental health problems during menstruation (p-value = .032), and body mass index (p-value = .001). Multivariate hierarchical logistic regression analysis showed only 2 variables BMI (a-OR 1.156,95% CI (1.067-1.242), p-value = .000), and typical cycle length (a-OR 2.278, 95% CI (1.079-4.809), p-value = .003) were significant. The present study showed that BMI and menstrual cycle length were most closely associated with the incidence of PCOS, which is important in diagnosing and treating the condition. Considering the high incidence of PCOS among women of reproductive age and its potential for significant health implications, it would be prudent to incorporate inquiries regarding mental health concerns and menstrual patterns into routine medical assessments for this demographic analysis. This approach aims to ascertain whether additional diagnostic evaluations and screenings for PCOS are warranted.

多囊卵巢综合征(PCOS)是一种常见的内分泌疾病,主要影响育龄妇女。多囊卵巢综合征在青春期女性中尤为常见,尽管可能会造成不良后果,但她们却得不到充分的诊断。使用多囊卵巢综合症筛查问卷有可能有助于早期发现症状。本研究的目的是观察自制问卷是否有助于清楚地认知与多囊卵巢综合征相关的精神压力和月经特征等相关情况。在这项研究中,我们根据修改后的鹿特丹标准,选择了年龄在 17-40 岁之间、患有或不患有多囊卵巢综合征的女性,让她们根据多囊卵巢综合征的症状和体征填写自制问卷,主要侧重于精神压力和月经特征。研究人员采用 SPSS 软件进行单变量分析,以阐明多囊卵巢综合征的组成因素、人口统计因素和生活方式特征之间的关联,从而深入了解这些变量之间的相互关系。64 名患有多囊卵巢综合症的妇女和 141 名未患有多囊卵巢综合症的妇女参与了本研究。本研究显示,月经初潮年龄(p-value= .043)、典型周期长度(p-value= .000)、月经期间的心理健康问题(p-value= .032)和体重指数(p-value= .001)对多囊卵巢综合征有很大影响。多变量分层逻辑回归分析显示,只有体重指数(a-OR 1.156,95% CI (1.067-1.242),p-value = .000)和典型周期长度(a-OR 2.278,95% CI (1.079-4.809),p-value = .003)这两个变量具有显著性。本研究表明,体重指数和月经周期长度与多囊卵巢综合征的发病率关系最为密切,这对于诊断和治疗该疾病非常重要。考虑到多囊卵巢综合症在育龄妇女中的高发病率及其对健康的潜在重大影响,在对这一人口统计学分析进行常规医疗评估时,将有关心理健康问题和月经模式的询问纳入其中是谨慎之举。这种方法旨在确定是否需要对多囊卵巢综合症进行额外的诊断评估和筛查。
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引用次数: 0
Statement of Retraction: Comparison of myo-inositol and metformin on mental health parameters and biomarkers of oxidative stress in women with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled trial. 撤回声明:肌醇和二甲双胍对多囊卵巢综合征妇女心理健康参数和氧化应激生物标志物的影响比较:一项随机、双盲、安慰剂对照试验。
IF 3.1 3区 医学 Q1 Medicine Pub Date : 2024-12-01 Epub Date: 2024-05-17 DOI: 10.1080/0167482X.2024.2346385
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引用次数: 0
Retracted article: The effects of fish oil omega-3 fatty acid supplementation on mental health parameters and metabolic status of patients with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled trial. 补充鱼油 omega-3 脂肪酸对多囊卵巢综合征患者精神健康参数和代谢状态的影响:随机、双盲、安慰剂对照试验。
IF 2.1 3区 医学 Q2 OBSTETRICS & GYNECOLOGY Pub Date : 2024-12-01 Epub Date: 2018-09-19 DOI: 10.1080/0167482X.2018.1508282
Mehrdad Amini, Fereshteh Bahmani, Fatemeh Foroozanfard, Zahra Vahedpoor, Amir Ghaderi, Mohsen Taghizadeh, Hassan Karbassizadeh, Zatollah Asemi

We, the Editor and Publisher of the Journal of Psychosomatic Obstetrics & Gynecology have retracted the following article:Mehrdad Amini, Fereshteh Bahmani, Fatemeh Foroozanfard, Zahra Vahedpoor, Amir Ghaderi, Mohsen Taghizadeh, Hassan Karbassizadeh & Zatollah Asemi (2018), The effects of fish oil omega-3 fatty acid supplementation on mental health parameters and metabolic status of patients with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled trial. Journal of Psychosomatic Obstetrics & Gynecology, DOI: 10.1080/0167482X.2018.1508282.Following publication, significant concerns were raised by a third party 1 about the integrity of the data and the reported findings in the article.When approached for an explanation, the authors and their institution have been cooperative in providing some responses and documents. To verify the reported findings, the article and the documents provided by the authors were further evaluated by the journal editorial team, and also sent for review by an external statistical reviewer.Both the journal editorial team and the external statistical reviewer were unable to confirm the integrity of the trial design and the main outcome of the external review was that the article's results and conclusions are unreliable. Therefore, as the editorial team no longer have confidence in the reported conclusions the decision has been made to retract the article.The authors listed in the publication have been informed. The authors do not agree with the retraction.We have been informed in our decision-making by our editorial policies and the COPE guidelines.The retracted article will remain online to maintain the scholarly record, but it will be digitally watermarked on each page as 'Retracted'.

研究目的本研究旨在评估补充鱼油欧米加-3 脂肪酸对多囊卵巢综合征(PCOS)女性心理健康参数和代谢状况的影响:这项随机双盲安慰剂对照试验针对 60 名患有多囊卵巢综合征的女性进行,她们的年龄在 18-40 岁之间。参与者被随机分为两组,每天午餐后服用 2 × 1000 毫克鱼油欧米伽-3 脂肪酸(30 人)或安慰剂(30 人),连续服用 12 周。对基线和 12 周干预后的代谢状况进行量化:与安慰剂相比,摄入欧米伽-3 脂肪酸可显著改善贝克抑郁量表(Beck Depression Inventory)[β(干预后治疗组之间平均结果测量值的差异)-1.05;95% CI:-1.84,-0.26;p = .01]、一般健康问卷(β-1.68;95% CI:-3.12,-0.24;p = .02)和抑郁、焦虑和压力量表(β-2.03;95% CI:-3.60,-0.46;p = .01)。补充欧米伽-3 脂肪酸可显著降低血清胰岛素水平(β -2.09 µIU/mL; 95% CI: -3.77, -0.41; p = .01)、胰岛素抵抗平衡模型评估(β -0.74; 95% CI: -1.13, -0.34; p 结论:补充欧米伽-3 脂肪酸可显著降低血清胰岛素水平:总体而言,多囊卵巢综合征患者连续 12 周补充欧米伽-3 脂肪酸对心理健康参数、胰岛素代谢、总睾酮、多毛症以及一些炎症指标和氧化应激均有益处。
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引用次数: 0
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Journal of Psychosomatic Obstetrics & Gynecology
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