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Progression of depression and anxiety symptoms in pregnancies conceived by assisted reproductive technology in the United States. 美国辅助生殖技术妊娠中抑郁和焦虑症状的进展
IF 3.1 3区 医学 Q2 OBSTETRICS & GYNECOLOGY Pub Date : 2022-06-01 DOI: 10.1080/0167482X.2021.1971193
Michael K Simoni, Kathryn Gilstad-Hayden, Syed H Naqvi, Lubna Pal, Kimberly Ann Yonkers

Purpose: Women who utilize assisted-reproductive technology (ART) to achieve pregnancy experience unique circumstances before and during their pregnancy. This study aims to examine the progression of mental health in pregnant women who conceived via various methods of ART to understand gestational time periods of emotional stability or risk specific to these populations.

Methods: Secondary analysis of the Yale Pink and Blue Study - a prospective cohort involving women from 137 obstetrical practices in the northeastern United States between 2005-2009. Depressive and anxiety symptoms among spontaneous, planned pregnancies were compared to ART pregnancies using the Edinburgh Postnatal Depression Scale (EPDS) and its anxiety subscale (EPDS-3A), respectively. Generalized Estimating Equations were used to compare group changes (EPDS and EPDS-3A score threshold ≥10) at timepoints of <17 weeks (T1), 28(±2) weeks (T2), and 8(±4) weeks postpartum (T3).

Results: 1,466 spontaneous, planned pregnancies were compared to 191 pregnancies conceived via ART. Prevalence of depressive symptoms were similar between conception groups. Change in prevalence over time differed significantly between those groups (from T1 to T3 (β 0.59), as well as between spontaneous pregnancies compared to autologous gamete ART pregnancies (from T1 to T2 (β 0.48) and T1 to T3 (β 0.65). Course of anxiety did not differ between conception groups.

Conclusions: Women who conceive via ART have different rates of change in depressive symptoms throughout gestation compared to women with spontaneous pregnancies.

目的:利用辅助生殖技术(ART)实现怀孕的妇女在怀孕前和怀孕期间经历了独特的情况。本研究旨在研究通过各种ART方法怀孕的孕妇的心理健康进展,以了解这些人群的情绪稳定或风险的妊娠期。方法:对耶鲁粉红和蓝色研究进行二次分析,该研究是一项前瞻性队列研究,涉及2005-2009年间美国东北部137家产科诊所的妇女。采用爱丁堡产后抑郁量表(EPDS)及其焦虑子量表(EPDS- 3a)对自然妊娠、计划妊娠与ART妊娠的抑郁和焦虑症状进行比较。采用广义估计方程比较各组在以下时间点的变化(EPDS和EPDS- 3a评分阈值≥10)结果:1466例自然、计划妊娠与191例ART妊娠进行比较。怀孕组之间抑郁症状的患病率相似。随着时间的推移,这些组之间(从T1到T3 (β 0.59))以及自然妊娠与自体配子ART妊娠(从T1到T2 (β 0.48)和T1到T3 (β 0.65))之间的患病率变化差异显著。不同受孕组的焦虑病程无差异。结论:与自然妊娠的妇女相比,通过抗逆转录病毒治疗怀孕的妇女在整个妊娠期间抑郁症状的变化率不同。
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引用次数: 4
Patient-specific affect-abdominal pain interactions in endometriosis: an experience sampling method (ESM) study 子宫内膜异位症患者特异性影响-腹痛相互作用:经验抽样方法(ESM)研究
IF 3.1 3区 医学 Q2 OBSTETRICS & GYNECOLOGY Pub Date : 2022-03-28 DOI: 10.1080/0167482X.2022.2053844
E. van Barneveld, M. de Hertogh, L. Vork, N. van Hanegem, F. V. van Osch, J. Kruimel, M. Bongers, C. Leue, A. Lim
Abstract Objectives Cross-sectional studies show that endometriosis-related pain is associated with affect. Measuring these symptoms in real-time in a longitudinal perspective yields the ability to analyze the temporal relationship between variables. The aim was to evaluate the association between affect and abdominal pain, using the Experience Sampling Method (ESM) as a real-time, randomly repeated assessment. Methods Thirty-four endometriosis patients and 31 healthy subjects completed up to 10 real-time self-assessments concerning abdominal pain and affective symptoms during seven consecutive days. Results Endometriosis patients experienced more abdominal pain and negative affective symptoms, and scored lower on positive affect compared to healthy controls. A significant association was found between abdominal pain and both positive and negative affect in endometriosis patients. For healthy controls, less strong or non-significant associations were found. When looking at abdominal pain as a predictor for affect and vice versa, we found that only in endometriosis patients, pain was subsequently accompanied by negative affect, and positive affect may alleviate pain in these patients. Conclusions This study confirms a concurrent and temporal relationship between affect and abdominal pain in endometriosis patients and supports the use of real-time symptom assessment to interpret potential influencers of abdominal complaints in patients with endometriosis.
目的横断面研究表明,子宫内膜异位症相关疼痛与情感相关。从纵向角度实时测量这些症状可以分析变量之间的时间关系。目的是评估情绪与腹痛之间的关系,使用经验抽样法(ESM)作为实时、随机重复的评估。方法34例子宫内膜异位症患者和31名健康者在连续7天内完成多达10项关于腹痛和情感症状的实时自我评估。结果与健康对照组相比,子宫内膜异位症患者经历了更多的腹痛和负面情绪症状,并且在积极情绪方面得分较低。子宫内膜异位症患者腹痛与积极和消极影响之间存在显著关联。在健康对照中,发现了不太强烈或不显著的关联。当我们将腹痛作为情绪的预测因素,反之亦然时,我们发现只有在子宫内膜异位症患者中,疼痛随后会伴随着负面情绪,而积极情绪可能会减轻这些患者的疼痛。结论:本研究证实了子宫内膜异位症患者的情绪与腹痛之间存在同步和时间关系,并支持使用实时症状评估来解释子宫内膜异位症患者腹部主诉的潜在影响因素。
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引用次数: 4
Sexual activity based fears during pregnancy, sexual function and dyadic adjustment in couples who are expecting their first child 怀孕期间基于性行为的恐惧,期待第一个孩子的夫妇的性功能和二元调整
IF 3.1 3区 医学 Q2 OBSTETRICS & GYNECOLOGY Pub Date : 2022-03-27 DOI: 10.1080/0167482X.2022.2052844
C. de Pierrepont, A. Brassard, Katherine Bécotte, I. Lessard, V. Polomeno, K. Péloquin
Abstract Purpose: Sexual activity based fears during pregnancy are common, but very few studies have examined their association with relationship variables. Secondary analysis of associations between these fears during pregnancy and both partners’ sexual function and dyadic adjustment were conducted. Materials and Methods: A sample of 67 French-Canadian first-time parenting couples living in Ontario completed online questionnaires on sexual activity based fears, sexual function, and dyadic adjustment as experienced during pregnancy. Results: While one-third of participants reported no fears, other couples experienced one to six fears, the two most common fears among partners being inducing labor and causing a miscarriage. Dyadic path analyses supported indirect associations between sexual activity based fears and lower dyadic adjustment via poorer sexual function. During pregnancy, these fears in women and men are associated with poorer dyadic adjustment in both partners through the women’s poorer sexual function. Conclusion: These findings suggest including prenatal sexual activity based fears in perinatal sexuality counseling, education, and interventions.
目的:怀孕期间基于性行为的恐惧是常见的,但很少有研究调查其与关系变量的关系。对怀孕期间的这些恐惧与双方的性功能和二元调整之间的关系进行了二次分析。材料和方法:67对居住在安大略省的法裔加拿大人首次生育的夫妇完成了基于怀孕期间的性活动恐惧、性功能和二元调整的在线问卷调查。结果:三分之一的参与者表示没有恐惧,而其他夫妇则有一到六种恐惧,其中最常见的两种恐惧是引产和流产。并矢路径分析支持基于恐惧的性行为与通过较差的性功能而产生的较低的并矢调整之间的间接关联。在怀孕期间,女性和男性的这些恐惧与伴侣双方较差的二元调节有关,因为女性的性功能较差。结论:这些发现建议将产前性行为恐惧纳入围产期性咨询、教育和干预中。
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引用次数: 2
The complex effects of maternal expectations on postpartum depressive symptoms: when does a protective factor become a risk factor? 母亲期望对产后抑郁症状的复杂影响:保护因素何时成为危险因素?
IF 3.1 3区 医学 Q2 OBSTETRICS & GYNECOLOGY Pub Date : 2022-03-01 Epub Date: 2020-07-23 DOI: 10.1080/0167482X.2020.1795826
Rotem Kahalon, Gil Yanushevsky Cnaani, Heidi Preis, Yael Benyamini

Purpose: The present study assessed the effects of several prenatal maternal expectations on postpartum depression (PPD), while considering two relevant factors - incongruence between planned and actual birth and the rigidity of the birth plan - that can affect whether maternal expectations act as protective factors or risk factors for PPD.

Methods: Primiparous women (N = 527) were recruited to a longitudinal study about women's birth choices and experiences. At time 1, during pregnancy, women completed a questionnaire assessing prenatal depression, preferred birth plan, birth plan flexibility-rigidity and maternal expectations (i.e. Natural-Fulfillment, Infant-Reflects-Mothering, Sacrifice). At time 2, two-months post-partum, they reported their actual birth mode and answered a questionnaire assessing their PPD symptoms.

Results: Natural-fulfillment maternal expectations were negatively related to PPD symptoms. Yet, the interaction of high natural-fulfillment expectations with an unfulfilled birth plan and the rigidity of the birth plan, served as a risk factor for PPD symptomatology.

Conclusions: Understanding the conditions under which specific prenatal maternal expectations serve as a risk factor for PPD, can help healthcare providers identify women who are at high risk for developing PPD symptoms and plan preemptive interventions.

目的:本研究评估了几种产前产妇期望对产后抑郁症(PPD)的影响,同时考虑了两个相关因素-计划生育与实际分娩不一致和分娩计划的刚性-可能影响产妇期望是PPD的保护因素还是危险因素。方法:对527例初产妇女进行生育选择和生育经历的纵向研究。在第一阶段,在怀孕期间,女性完成了一份问卷,评估产前抑郁、首选生育计划、生育计划的灵活性-刚性和母亲的期望(即自然满足、婴儿反思-育儿、牺牲)。在产后2、2个月时,她们报告了自己的实际分娩方式,并回答了一份评估她们产后抑郁症症状的问卷。结果:自然满足的母亲期望与PPD症状呈负相关。然而,高自然实现期望与未实现的生育计划和生育计划的刚性的相互作用,是PPD症状学的危险因素。结论:了解特定的产前母亲期望作为PPD风险因素的条件,可以帮助医疗保健提供者识别发生PPD症状的高危妇女,并计划先发制人的干预措施。
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引用次数: 3
Psychological domain of quality of life, depression and anxiety levels in in vitro fertilization/intracytoplasmic sperm injection cycles of women with endometriosis: a prospective study. 子宫内膜异位症患者体外受精/胞浆内单精子注射周期中生活质量、抑郁和焦虑水平的心理域:一项前瞻性研究
IF 3.1 3区 医学 Q2 OBSTETRICS & GYNECOLOGY Pub Date : 2022-03-01 Epub Date: 2020-07-08 DOI: 10.1080/0167482X.2020.1787978
M U Ceran, N Yilmaz, E N Ugurlu, N Erkal, A S Ozgu-Erdinc, Y Tasci, H C Gulerman, Y Engin-Ustun

Objective: To evaluate the psychological domain of quality of life (PDQoL), anxiety and depression levels of infertile women with endometriosis versus non endometriosis who applied for Assisted Reproductive Technologies (ART).

Method: This prospective case-control study compromised a total of 105 women who applied for IVF/ICSI program. Ninety-three women were divided into two groups as endometriosis (n = 37) and non-endometriosis (n = 56) after 12 patients who refused to participate in the study were excluded. The WHOQOL-BREF questionnaire, Beck Depression and Anxiety Inventory scales were used to determine the psychological stress levels.

Results: A significant difference was found between the endometriosis and non-endometriosis groups regarding depression scores, while no significant difference was reported with respect to PDQoL and anxiety (p < 0.01, p = 0.897 and p = 0.058, respectively). A weak but significant correlation was observed between depression and endometriosis (CC: 0.435, p < 0.01). Though anxiety scores were found to be higher in endometriosis group this can not reach statistical significance (p = 0.058). Impact of PDQoL, depression and anxiety scores on pregnancy outcomes were found to be insignificant.

Conclusion: Women with endometriosis seem to be more susceptible to depression and anxiety than women without endometriosis. Although infertility treatment outcomes are not found to be significantly affected, the impact of depression and anxiety over ART treatment success merit further research.

目的:评价子宫内膜异位症不孕妇女与非子宫内膜异位症不孕妇女申请辅助生殖技术(ART)的生活质量(PDQoL)、焦虑和抑郁水平的心理域。方法:本前瞻性病例对照研究共纳入105例申请体外受精/ICSI方案的妇女。93名女性被分为子宫内膜异位症(n = 37)和非子宫内膜异位症(n = 56)两组,其中12名患者拒绝参与研究。采用WHOQOL-BREF问卷、Beck抑郁焦虑量表测定心理应激水平。结果:子宫内膜异位症组与非子宫内膜异位症组抑郁评分差异有统计学意义,而PDQoL、焦虑评分差异无统计学意义(p = 0.897、p = 0.058)。抑郁症与子宫内膜异位症之间存在微弱但显著的相关性(CC: 0.435, p = 0.058)。PDQoL、抑郁和焦虑评分对妊娠结局的影响不显著。结论:有子宫内膜异位症的女性比没有子宫内膜异位症的女性更容易抑郁和焦虑。虽然未发现不孕不育治疗结果受到显著影响,但抑郁和焦虑对ART治疗成功的影响值得进一步研究。
{"title":"Psychological domain of quality of life, depression and anxiety levels in <i>in vitro</i> fertilization/intracytoplasmic sperm injection cycles of women with endometriosis: a prospective study.","authors":"M U Ceran,&nbsp;N Yilmaz,&nbsp;E N Ugurlu,&nbsp;N Erkal,&nbsp;A S Ozgu-Erdinc,&nbsp;Y Tasci,&nbsp;H C Gulerman,&nbsp;Y Engin-Ustun","doi":"10.1080/0167482X.2020.1787978","DOIUrl":"https://doi.org/10.1080/0167482X.2020.1787978","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the psychological domain of quality of life (PDQoL), anxiety and depression levels of infertile women with endometriosis versus non endometriosis who applied for Assisted Reproductive Technologies (ART).</p><p><strong>Method: </strong>This prospective case-control study compromised a total of 105 women who applied for IVF/ICSI program. Ninety-three women were divided into two groups as endometriosis (<i>n</i> = 37) and non-endometriosis (<i>n</i> = 56) after 12 patients who refused to participate in the study were excluded. The WHOQOL-BREF questionnaire, Beck Depression and Anxiety Inventory scales were used to determine the psychological stress levels.</p><p><strong>Results: </strong>A significant difference was found between the endometriosis and non-endometriosis groups regarding depression scores, while no significant difference was reported with respect to PDQoL and anxiety (<i>p</i> < 0.01, <i>p</i> = 0.897 and <i>p</i> = 0.058, respectively). A weak but significant correlation was observed between depression and endometriosis (CC: 0.435, <i>p</i> < 0.01). Though anxiety scores were found to be higher in endometriosis group this can not reach statistical significance (<i>p</i> = 0.058). Impact of PDQoL, depression and anxiety scores on pregnancy outcomes were found to be insignificant.</p><p><strong>Conclusion: </strong>Women with endometriosis seem to be more susceptible to depression and anxiety than women without endometriosis. Although infertility treatment outcomes are not found to be significantly affected, the impact of depression and anxiety over ART treatment success merit further research.</p>","PeriodicalId":50072,"journal":{"name":"Journal of Psychosomatic Obstetrics & Gynecology","volume":"43 1","pages":"66-73"},"PeriodicalIF":3.1,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/0167482X.2020.1787978","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38134010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Medical considerations in delusion of pregnancy: a systematic review. 妊娠妄想的医学考虑:系统回顾。
IF 3.1 3区 医学 Q2 OBSTETRICS & GYNECOLOGY Pub Date : 2022-03-01 Epub Date: 2020-06-29 DOI: 10.1080/0167482X.2020.1779696
Soumya Gogia, Anastasia Grieb, Albert Jang, Mollie R Gordon, John Coverdale

Purpose: Delusions of pregnancy are associated with functional impairment and psychological distress. Previous works have focused on characterizing their etiology and identifying contributory social and cultural factors. The purpose of this review is to give an overview of the literature on medical or surgical comorbidities associated with delusions of pregnancy.

Methods: We searched Google Scholar, PubMed, and PsycInfo using the terms "pregnancy delusion," "delusional pregnancy," "pseudocyesis", and "false/pseudo/phantom/spurious pregnancy" to identify all published cases of delusional pregnancies. We included cases in which medical or surgical factors might have contributed to the delusion. We extracted the following information from selected case reports: patient age, psychiatric diagnoses, medications, medical comorbidities, somatic complaints, treatment, and outcome.

Results: We found that 23 of 140 cases (16.4%) were potentially influenced by concomitant medical or surgical conditions including gallstones, abdominal tumors, hyperprolactinemia, constipation, a tubal cyst, and esophageal achalasia. Medical or surgical treatment was pursued in 15 of these 23 cases, followed by mitigation of the delusion in ten cases.

Conclusions: We emphasize the importance of a thorough workup including physical and gynecological examinations in patients presenting with a delusion of pregnancy. Clinicians should recognize and overcome potential barriers to undertaking comprehensive assessments in order to prevent delays in management and treatment of underlying medical or surgical conditions.

目的:妊娠妄想与功能障碍和心理困扰有关。以前的工作集中在表征其病因和确定贡献的社会和文化因素。本综述的目的是对与妊娠妄想相关的医学或外科合并症的文献进行综述。方法:我们在Google Scholar、PubMed和PsycInfo中搜索“妊娠妄想”、“妄想妊娠”、“假性妊娠”和“假/伪/幻/假妊娠”,以确定所有已发表的妄想妊娠病例。我们纳入了可能导致幻觉的医疗或手术因素。我们从选定的病例报告中提取了以下信息:患者年龄、精神诊断、药物、医疗合并症、躯体主诉、治疗和结果。结果:我们发现140例病例中有23例(16.4%)可能受到伴随的内科或外科疾病的影响,包括胆结石、腹部肿瘤、高催乳素血症、便秘、输卵管囊肿和食道失弛缓症。在这23例中,有15例接受了药物或手术治疗,10例的妄想得到了缓解。结论:我们强调了一个彻底的工作,包括身体和妇科检查的重要性,在病人表现出怀孕妄想。临床医生应认识到并克服进行全面评估的潜在障碍,以防止在管理和治疗潜在的医疗或手术条件方面出现延误。
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引用次数: 4
Stigma predicting fertility quality of life among Chinese infertile women undergoing in vitro fertilization-embryo transfer. 污名预测中国接受体外受精-胚胎移植的不孕妇女的生育质量。
IF 3.1 3区 医学 Q2 OBSTETRICS & GYNECOLOGY Pub Date : 2022-03-01 Epub Date: 2020-07-07 DOI: 10.1080/0167482X.2020.1778665
Xiaoyu Jing, Wei Gu, Xiuli Xu, Chunfang Yan, Peijuan Jiao, Lu Zhang, Xiaomei Li, Xiaoqin Wang, Wenru Wang

Objective: To investigate stigma and fertility quality of life (FertiQoL) and identify predictors of FertiQoL in Chinese infertile women undergoing in vitro fertilization-embryo transfer (IVF-ET).

Methods: A descriptive correlational design was adopted to investigate the association between stigma and FertiQoL in 588 infertile women undergoing IVF-ET. The personal information questionnaire, Infertility Stigma Scale (ISS) and FertiQoL tool were used to measure study variables.

Results: The mean scores of ISS and FertiQoL were 62.59 (SD = 21.58) and 63.64 (SD = 13.72), respectively. There were significant differences of ISS scores among participants with different educational level, residence, occupation, religious belief, financial condition, age group, duration of infertility and infertility treatment, while significant differences of the FertiQoL scores were found in participants with different insurance status, determinism of etiology, infertile type, duration of infertility treatment and cycles of IVF-ET. Pearson's correlation analysis showed stigma was negatively correlated with FertiQoL (r = -0.081 to -0.669, p < .05). The self-devaluation (β = -0.290, p < .001), social withdrawal (β = -0.237, p < .001), family stigma (β = -0.217, p < .001) and insurance status (β = 0.066, p=.035) were identified as the significant predictor of FertiQoL accounting for 43.5% of variance.

Conclusions: The stigma was significantly associated with FertiQoL in infertile women undergoing IVF-ET with higher level of stigma predicting poorer FertiQoL. More psychological support should be provided to infertile women to reduce stigma and improve FertiQoL.

目的:探讨中国接受体外受精-胚胎移植(IVF-ET)的不孕妇女的耻辱感和生育生活质量(FertiQoL),并确定其预测因素。方法:采用描述性相关设计对588例接受IVF-ET治疗的不孕症妇女进行柱头与FertiQoL的相关性研究。采用个人信息问卷、不孕症耻感量表(ISS)和FertiQoL工具对研究变量进行测量。结果:ISS和FertiQoL的平均得分分别为62.59分(SD = 21.58)和63.64分(SD = 13.72)。不同教育程度、居住地、职业、宗教信仰、经济状况、年龄、不孕持续时间和不孕治疗时间的被试在ISS得分上存在显著差异,而不同保险状况、病因决定论、不孕类型、不孕治疗持续时间和IVF-ET周期的被试在FertiQoL得分上存在显著差异。Pearson相关分析显示,柱头与FertiQoL呈负相关(r = -0.081 ~ -0.669, p p p p= 0.035),为FertiQoL的显著预测因子,占方差的43.5%。结论:在接受IVF-ET的不孕妇女中,耻辱感与FertiQoL显著相关,较高的耻辱感水平预示着较差的FertiQoL。应加强对不孕妇女的心理支持,减少耻辱感,提高生育质量。
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引用次数: 20
Association between nausea and vomiting of pregnancy and postpartum depression: the Japan Environment and Children's Study. 妊娠期恶心呕吐与产后抑郁的关系:日本环境与儿童研究。
IF 3.1 3区 医学 Q2 OBSTETRICS & GYNECOLOGY Pub Date : 2022-03-01 Epub Date: 2020-03-04 DOI: 10.1080/0167482X.2020.1734792
Sifa Marie Joelle Muchanga, Masamitsu Eitoku, Etongola Papy Mbelambela, Hitoshi Ninomiya, Tatsuo Iiyama, Kaori Komori, Kahoko Yasumitsu-Lovell, Naomi Mitsuda, Rahma Rashid Tozin, Nagamasa Maeda, Mikiya Fujieda, Narufumi Suganuma

Objective: Postpartum depression (PPD) is a global emotional distress that affects women and their offspring regardless of their culture. The association between nausea and vomiting of pregnancy (NVP) and PPD has been widely described only for the severe form of NVP. We aimed to assess the relationship between PPD and NVP with regards to its severity.

Methods: Data from the Japan Environment and Children's Study (JECS), a birth cohort study, were analyzed. PPD was assessed using the Edinburgh Postnatal Depression Scale (EPDS). Multiple logistic regression models were performed to assess the association between NVP and PPD.

Results: Out of the 80,396 women included in the study 14% had PPD. Among them 4,640 (42.1%) had mild NVP; 3,295 (29.9%) had moderate NVP whereas 1,481 (13.4%) had severe NVP. All forms of NVP were associated with PPD and the association gradually increased with the severity of NVP symptoms with odd ratio (OR): 1.26; 95% confidence interval (CI): 1.18-1.35 for mild, OR: 1.28; 95% CI: 1.19-1.38 for moderate and OR: 1.54; 95% CI: 1.42-1.68 for severe NVP.

Conclusion: Japanese women with NVP were more susceptible to develop PPD and the more severe the NVP symptoms were, the greater the risk of PPD. Thus, close monitoring of NVP-affected women is recommended.

目的:产后抑郁症(PPD)是一种全球性的情绪困扰,不论其文化背景如何,都会影响到女性及其后代。妊娠期恶心和呕吐(NVP)与PPD之间的关联已被广泛描述,但仅限于严重形式的NVP。我们的目的是评估PPD和NVP在严重程度上的关系。方法:对日本环境与儿童研究(JECS)的出生队列研究数据进行分析。PPD采用爱丁堡产后抑郁量表(EPDS)进行评估。采用多元logistic回归模型评估NVP与PPD之间的关系。结果:在80396名参与研究的女性中,14%患有产后抑郁症。其中轻度NVP 4640例(42.1%);3295例(29.9%)为中度NVP, 1481例(13.4%)为重度NVP。所有形式的NVP均与PPD相关,且随着NVP症状的严重程度,相关性逐渐增强,奇数比(OR): 1.26;轻度95%置信区间(CI): 1.18-1.35, OR: 1.28;中度95% CI: 1.19-1.38, OR: 1.54;严重NVP的95% CI: 1.42-1.68。结论:日本NVP患者更易发生PPD,且NVP症状越严重,发生PPD的风险越大。因此,建议密切监测受nvp影响的妇女。
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引用次数: 9
Post-traumatic stress following total hysterectomy for benign disease: an observational prospective study. 良性疾病全子宫切除术后的创伤后应激:一项观察性前瞻性研究。
IF 3.1 3区 医学 Q2 OBSTETRICS & GYNECOLOGY Pub Date : 2022-03-01 Epub Date: 2020-04-22 DOI: 10.1080/0167482X.2020.1752174
Jvan Casarin, Marta Ielmini, Antonella Cromi, Antonio Simone Laganà, Nicola Poloni, Camilla Callegari, Fabio Ghezzi

Purpose: Over the last decade, there has been growing interest in the psychophysical integrity of surgical patients in the context of healthcare events. In the present study, we aimed to evaluate the incidence rate of postoperative distress symptoms, namely post-traumatic stress disorder (PTSD), following total hysterectomy for benign disease. We also investigated possible associations between sociodemographic characteristics, clinical outcomes, anxiety, depression, and PTSD.

Methods: We prospectively enrolled 100 consecutive patients who underwent total hysterectomy for benign disease between 01/01/2019 and 15/04/2019. Demographic and surgical-related characteristics have been registered. The Hospital Anxiety and Depression Scale (HADS) questionnaire was administered preoperatively (Time1), postoperatively (Time2), and at follow-up clinical evaluation, between two and three months after surgery (Time3). PTSD was defined based on the results of the Post-traumatic Stress Disorder Checklist for DSM-5 (PCL-5) at Time3.

Results: At Time3, the median PCL-5 score was 12,8 (0-70), and 16.4% of patients had PTSD symptoms (PCL-5 > 33). No correlation between sociodemographic or gynecologic characteristics and PTSD was detected. A significant association between depression (HADS > 8) at Time2 (p = 0.002) and Time3 (p < 0.001) and PTSD symptoms was shown.

Conclusion: Hysterectomy for benign disease is associated with a non-negligible risk of PTDS; the use of the HADS questionnaires might be useful to select patients who might benefit from dedicated psychological support.

目的:在过去的十年中,在医疗保健事件的背景下,对外科患者的心理生理完整性的兴趣越来越大。在本研究中,我们旨在评估良性疾病全子宫切除术后的术后痛苦症状,即创伤后应激障碍(PTSD)的发生率。我们还调查了社会人口学特征、临床结果、焦虑、抑郁和创伤后应激障碍之间可能存在的关联。方法:我们前瞻性地招募了100例在2019年1月1日至2019年4月15日期间因良性疾病接受全子宫切除术的患者。已登记了人口统计学和外科相关特征。术前(Time1)、术后(Time2)和术后2 - 3个月(Time3)进行医院焦虑抑郁量表(HADS)问卷调查。PTSD的定义基于DSM-5创伤后应激障碍检查表(PCL-5)在Time3的结果。结果:Time3时,PCL-5评分中位数为12.8分(0-70分),16.4%的患者出现PTSD症状(PCL-5 > 33分)。未发现社会人口学或妇科特征与PTSD之间存在相关性。抑郁症(HADS > 8)在Time2 (p = 0.002)和Time3 (p)之间存在显著相关(p = 0.002)。结论:良性疾病子宫切除术与PTDS不可忽视的风险相关;使用HADS问卷可能有助于选择可能受益于专门心理支持的患者。
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引用次数: 6
Psychological variables and quality of life in women with endometriosis. 子宫内膜异位症患者的心理变量和生活质量。
IF 3.1 3区 医学 Q2 OBSTETRICS & GYNECOLOGY Pub Date : 2022-03-01 Epub Date: 2020-07-24 DOI: 10.1080/0167482X.2020.1784874
Madeleine Rees, Gundi Kiemle, Pauline Slade

Background: Endometriosis is a common gynecological condition which has been found to have a detrimental impact upon women's quality of life (QoL). This study investigated the impact of pain self-efficacy, health locus of control (HLOC), coping style and illness uncertainty on QoL in women with endometriosis.

Method: Two hundred and thirty women completed online questionnaires. Standard multiple regressions assessed the relationship between the psychological predictors and QoL.

Results: The psychological variables accounted for a statistically significant proportion of the variance (p < .0005) in scores across the four QoL domains. The model accounted for 55, 26, 10 and 32% of the scores in physical, psychological, social and environmental QoL domains, respectively. Pain self-efficacy made the largest unique contribution, followed by illness uncertainty.

Conclusions: Women's perception of their ability to manage their pain and how uncertain they felt about their condition, were important factors in QoL, particularly in the physical domain.

背景:子宫内膜异位症是一种常见的妇科疾病,已被发现对妇女的生活质量(QoL)产生不利影响。本研究探讨疼痛自我效能感、健康控制点(HLOC)、应对方式和疾病不确定性对子宫内膜异位症患者生活质量的影响。方法:230名女性完成在线问卷调查。标准多元回归评估心理预测因子与生活质量之间的关系。结果:心理变量占差异的统计显著比例(p)结论:女性对自己管理疼痛的能力的感知以及她们对自己状况的不确定程度,是生活质量的重要因素,特别是在身体方面。
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引用次数: 7
期刊
Journal of Psychosomatic Obstetrics & Gynecology
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