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Preemptive vs preventive coadministration of ibuprofen L-arginine and dexamethasone in lower third molar surgeries: a randomized controlled trial 在下第三磨牙手术中联合使用布洛芬-L-精氨酸和地塞米松的预防性与先发制人:随机对照试验
Pub Date : 2024-08-19 DOI: 10.1016/j.oooo.2024.08.008
Edson Luiz Cetira-Filho DDS MSc PhD, Paulo Goberlânio de Barros Silva DDS MSc PhD, Isabelle de Fátima Vieira Camelo Maia CP, Deysi Viviana Tenazoa Wong MSc PhD, Roberto César Pereira Lima-Júnior Sc PhD, Ravy Jucá Farias DDS, Mayara Alves dos Anjos DDS student, Said Goncalves da Cruz Fonseca CP MSc PhD, Thyciana Rodrigues Ribeiro DDS MSc PhD, Fábio Wildson Gurgel Costa DDS MSc PhD
To compare the effect of different preemptive and preventive analgesia strategies involving oral coadministration of ibuprofen-arginine (770 mg)–Ib-Ar and dexamethasone (8 mg)-DX, and their respective placebos (P-Ib-Ar and P-DX), four evaluation groups on inflammatory and laboratory parameters, impact on quality of life, pain catastrophizing perception and sleep quality related after lower third molar surgery. A randomized split-mouth, triple-blind, controlled clinical trial was conducted with 48 volunteers. They were allocated depending on the use of Ib-Ar or DX, 1 hour before surgery or immediately postoperatively, discriminating the groups: G1 (Ib-Ar + DX), G2 (Ib-Ar + P-DX), G3 (P-Ib-Ar + DX), and G4 (P-Ib-Ar + P-DX). Pain peaks occurred after 2 h (P-Ib-Ar groups) ( = .003), while the other groups showed peak pain after 4 h ( < .05). Regarding the edema: groups treated with placebos measurements significantly reduced without returning to baseline ( < .001). Regarding laboratory parameters: MPO and MDA levels, the G1 group ( < .001) was the only one showing significant reduction. The use of preemptive and preventive analgesia strategies of Ib-Ar and DX showed that the combined use delayed peak pain, with no difference in edema and trismus. The benefit of coadministration of both strategies was superior to isolated use of drugs.
目的:比较不同的抢先和预防性镇痛策略(包括口服联合给药布洛芬-精氨酸(770 毫克)-Ib-Ar 和地塞米松(8 毫克)-DX,以及各自的安慰剂(P-Ib-Ar 和 P-DX))、四个评估组对下第三磨牙手术后炎症和实验室参数、对生活质量的影响、疼痛灾难化感知和睡眠质量的影响。对 48 名志愿者进行了随机分口三盲对照临床试验。他们根据术前 1 小时或术后立即使用 Ib-Ar 或 DX 的情况进行分配,并区分为不同的组别:G1组(Ib-Ar + DX)、G2组(Ib-Ar + P-DX)、G3组(P-Ib-Ar + DX)和G4组(P-Ib-Ar + P-DX)。疼痛峰值出现在 2 小时后(P-Ib-Ar 组)(= .003),而其他组的疼痛峰值出现在 4 小时后(< .05)。关于水肿:使用安慰剂治疗的各组水肿明显减轻,没有恢复到基线水平 ( < .001)。关于实验室参数:MPO和MDA水平,G1组(< .001)是唯一出现显著下降的组别。使用 Ib-Ar 和 DX 的先期和预防性镇痛策略表明,联合使用可延缓疼痛峰值,而在水肿和肢体瘫痪方面没有差异。联合使用这两种策略的效果优于单独使用药物。
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引用次数: 0
Efficacy evaluation of a high-precision simulator of posterior pharyngeal flap pharyngoplasty 咽后皮瓣咽成形术高精度模拟器的疗效评估
Pub Date : 2024-08-09 DOI: 10.1016/j.oooo.2024.07.012
Yulang Xu BDS, Hanyao Huang MD, Chao Yang MSc, Yang Li MD, Chenghao Li MD, Bing Shi MD, Jingtao Li MD, Yan Wang MD, Qian Zheng MD, Ni Zeng MD
To improve medical students’ preclinical skills and enable them to quickly comprehend the procedure of posterior pharyngeal flap surgery, our teaching team developed a surgical simulator specifically for pharyngeal flap surgery. Thirteen undergraduate students and 8 first-year residents trained from March to May 2023 participated in simulated surgical training. Initially, multimedia were used to explain and demonstrate to them relevant anatomy, surgical principles, and procedural steps. This was followed by independent simulated surgeries by the students, culminating in the completion of a questionnaire. Independent samples test was used for statistical analysis. Before the simulated surgery, the residents had a greater understanding of the surgical design compared with the undergraduate students. After the simulated surgery, the residents showed not only significantly greater levels of understanding of the surgical design but also increased familiarity with the surgical process and enhanced confidence in independent surgery compared with the undergraduate students. Both groups showed a notable increase in familiarity with the surgical process and confidence in performing surgery independently after the simulated surgery. The surgical simulator demonstrates high clinical fidelity and provides tactile feedback that closely resembles reality. It significantly enhances the understanding and mastery of surgical techniques for young doctors, ultimately improving their surgical skills.
为了提高医学生的临床前技能,使他们能够快速理解咽后皮瓣手术的过程,我们的教学团队专门开发了咽后皮瓣手术模拟器。2023 年 3 月至 5 月,接受培训的 13 名本科生和 8 名一年级住院医师参加了模拟手术培训。最初,我们使用多媒体向他们讲解和演示相关的解剖结构、手术原理和手术步骤。随后,学生们独立进行了模拟手术,最后完成了问卷调查。统计分析采用独立样本检验。与本科生相比,住院医师在模拟手术前对手术设计有了更深的理解。模拟手术后,与本科生相比,住院医师不仅对手术设计的理解程度明显提高,而且对手术过程的熟悉程度也有所提高,并增强了独立手术的信心。模拟手术后,两组学生对手术过程的熟悉程度和独立完成手术的信心都有明显提高。手术模拟器表现出高度的临床逼真性,提供的触觉反馈与现实非常相似。它大大增强了年轻医生对手术技巧的理解和掌握,最终提高了他们的手术技能。
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引用次数: 0
Evaluation of gingival thickness obtained from intraoral scanning registration with cone beam computed tomography at different acquisition modes 用锥束计算机断层扫描评估不同采集模式下通过口内扫描登记获得的牙龈厚度
Pub Date : 2024-08-09 DOI: 10.1016/j.oooo.2024.08.005
Luiz Eduardo Marinho-Vieira, Maria Clara Rodrigues Pinheiro, Deborah Queiroz Freitas, Reinhilde Jacobs, Christiano de Oliveira-Santos, Alexander Tadeu Sverzut, Matheus L. Oliveira
To investigate the reliability of gingival thickness measurements obtained from the registration of intraoral scans with cone beam computed tomography (CBCT) examinations at different acquisition modes. CBCT examinations of 9 porcine hemimandibles were acquired using the OP300 Maxio unit operating at the highest-dose protocol with the smallest voxel size as the reference standard for visualizing the gingival surface. Subsequently, the hemimandibles were surrounded by water to simulate soft tissue attenuation of radiation, and additional CBCT examinations were acquired in 4 modes: Endo, High-resolution, Standard-resolution, and Low-dose. These CBCT datasets were registered with corresponding intraoral scans obtained with the Carestream Dental 3600 intraoral scanning system using the Blue Sky Plan 4 software. Four oral radiologists measured the buccal gingival thickness on cross-sectional reconstructions at 4 measurement sites and 2 distances from the gingival margin in the CBCT reference standard examinations and examinations obtained with water and intraoral scan registration. Multifactorial analysis of variance was used to assess the influence of acquisition mode, measurement site, and distance from the gingival margin on measurements (α = 5%; statistical power = 90%). Buccal gingival thickness measurements obtained via CBCT after registration with intraoral scanning were not significantly influenced by acquisition mode ( = .153) or measurement site ( = .089). Gingival thickness measurements derived from the registration of intraoral scans with CBCT examinations at different acquisition modes appear to be reliable.
目的:研究在不同采集模式下,通过口内扫描与锥形束计算机断层扫描(CBCT)检查的配准所获得的牙龈厚度测量值的可靠性。使用 OP300 Maxio 设备,以最高剂量协议和最小体素尺寸作为牙龈表面可视化的参考标准,对 9 个猪半颌进行 CBCT 检查。随后,在半颌骨周围用水模拟软组织对辐射的衰减,并以 4 种模式进行额外的 CBCT 检查:内窥镜、高分辨率、标准分辨率和低剂量。这些 CBCT 数据集与使用蓝天计划 4 软件的 Carestream Dental 3600 口内扫描系统获得的相应口内扫描数据进行了登记。四名口腔放射科医生在 CBCT 参考标准检查和用水及口内扫描登记获得的检查中,在距离龈缘 4 个测量点和 2 个距离的横截面重建上测量了颊面龈厚度。多因素方差分析用于评估采集模式、测量部位和龈缘距离对测量结果的影响(α = 5%;统计功率 = 90%)。通过口内扫描登记后的 CBCT 获得的颊面龈厚度测量值不受采集模式(= 0.153)或测量部位(= 0.089)的显著影响。在不同采集模式下,通过口内扫描与 CBCT 检查配准得到的牙龈厚度测量结果似乎是可靠的。
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引用次数: 0
Antiresorptive therapy in combination with radiation results in enhanced risk for necrosis and associated complications 抗骨质吸收疗法与放射治疗相结合会增加坏死和相关并发症的风险
Pub Date : 2024-08-09 DOI: 10.1016/j.oooo.2024.07.008
Katharina Theresa Obermeier DMD MD, Wenko Smolka, Benjamin Palla, Moritz Kraus, David Steybe, Jens Tobias Hartung, Florian Nepomuk Fegg, Tim Hildebrandt, Ina Dewenter, Nicholas Callahan, Philipp Poxleitner, Sven Otto
Patients exposed to a combination of antiresorptive medication and radiotherapy of the head and neck area developing necrosis of the jaw in the course of treatment are extremely rare. Therefore, the aim of this study was to identify the outcome and complications in this highly vulnerable patient cohort. Seventeen patients who received both antiresorptive treatment and radiotherapy (medication-related osteonecrosis of the jaw/osteoradionecrosis = the [MRONJ/ORN] group) in the head and neck area were enrolled in this study. Included patients were treated in our department between 2005 and 2022. Four hundred twenty-four patients with MRONJ (the MRONJ group) and 138 patients with ORN of the jaw were enrolled as two control groups (the ORN group). Demographic data, lesion localization, date of primary diagnosis, clinical symptoms, type of therapy (surgical or non-surgical), details on antiresorptive treatment, outcome, and complications were recorded. Pathological fractures, continuity resection, and recurrence appear more often in patients who receive a combination of antiresorptive treatment and radiotherapy in the head and neck area compared with patients undergoing only one of these treatments. There was a statistically significant difference ( < .001) between the MRONJ/ORN group and the MRONJ group and the MRONJ/ORN group and the ORN group considering recurrence, fracture, and continuity resection. Patients with ORN combined with MRONJ have a 4-times higher risk for developing recurrence compared with patients with MRONJ and a 1.5-times higher risk for recurrence compared with patients with ORN. Jaw fracture and continuity resection appear more often in patients with MRONJ/ORN. Patients under antiresorptive therapy in combination with radiation therapy in the head and neck area have a higher risk for developing complications in case of osteonecrosis of the jaw. Therefore, a strict follow-up care schedule is highly recommended.
头颈部接受抗骨质吸收药物和放射治疗的患者在治疗过程中发生颌骨坏死的情况极为罕见。因此,本研究旨在确定这一极易受伤害的患者群体的治疗结果和并发症。本研究选取了头颈部同时接受抗骨质吸收治疗和放射治疗的17名患者(药物相关性颌骨坏死/骨坏死=[MRONJ/ORN]组)。所纳入的患者均在 2005 年至 2022 年期间在我科接受过治疗。424 名 MRONJ 患者(MRONJ 组)和 138 名颌骨 ORN 患者作为两个对照组(ORN 组)。研究人员记录了患者的人口统计学数据、病变定位、初诊日期、临床症状、治疗类型(手术或非手术)、抗骨吸收治疗的详细情况、疗效和并发症。与只接受其中一种治疗的患者相比,头颈部接受抗骨质吸收治疗和放疗联合治疗的患者更容易出现病理性骨折、连续性切除和复发。考虑到复发、骨折和连续性切除,MRONJ/ORN组与MRONJ组、MRONJ/ORN组与ORN组之间的差异有统计学意义(< .001)。ORN 合并 MRONJ 患者的复发风险是 MRONJ 患者的 4 倍,是 ORN 患者的 1.5 倍。MRONJ/ORN患者更容易发生颌骨骨折和连续性切除。头颈部接受抗骨质吸收治疗和放射治疗的患者发生颌骨骨坏死并发症的风险较高。因此,强烈建议严格执行随访护理计划。
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引用次数: 0
Severe odontogenic infections in patients with mental disorders—the challenge of ineffective initial treatment 精神障碍患者的严重牙源性感染--初期治疗无效的挑战
Pub Date : 2024-08-08 DOI: 10.1016/j.oooo.2024.08.002
Satu Manninen BDS, Johanna Snäll MD DDS PhD, Tero Puolakkainen DDS PhD, Aleksi Haapanen DDS PhD
This study clarified possible delays and deficiencies in severe odontogenic infection (OI) treatment in patients with mental disorders. Data of hospitalized patients with severe OI were evaluated retrospectively. The outcome variable was preceding health care visits prior to hospitalization. The primary predictor was patient's mental disorder. Explanatory variables were age, sex, smoking, heavy alcohol use, immunocompromised disease or medication, and time span from beginning of symptoms to hospitalization. Also, factors leading to intensive care unit (ICU) care were evaluated. Preceding visits prior to hospitalization were found in 61 (35.5%) out of 172 patients with OI. In total, 27 patients (15.7%) had a current mental disorder, more commonly in women (26.0%) than in men (8.1%) ( = .001). Patients with mental disorders had preceding health care visits related to the current infection notably more often than patients without recent psychiatric history (51.9% vs. 32.4%), = .053. Patient-related treatment delay remained nonsignificant. Heavy alcohol use ( = .010) and smoking ( = .025) predicted ICU treatment, but no association with patient's mental disorder was found. A patient's mental disorder can complicate diagnosis of OI. Effective and timely treatment requires the professional's ability to simultaneously identify the patient's mental health challenges and progressing OI.
本研究阐明了精神障碍患者在严重牙源性感染(OI)治疗中可能存在的延误和不足。研究人员对严重牙源性感染住院患者的数据进行了回顾性评估。结果变量是住院前的医疗就诊。主要预测因素是患者的精神障碍。解释变量包括年龄、性别、吸烟、酗酒、免疫力低下的疾病或药物以及从症状开始到住院的时间跨度。此外,还对导致重症监护室(ICU)护理的因素进行了评估。在 172 名 OI 患者中,有 61 人(35.5%)在住院前曾就诊。共有 27 名患者(15.7%)目前患有精神障碍,其中女性患者(26.0%)多于男性患者(8.1%)(= 0.001)。与近期无精神病史的患者(51.9% 对 32.4%)相比,有精神障碍的患者之前就诊与当前感染相关的次数明显增多(= .053)。与患者相关的治疗延迟仍然不显著。大量饮酒(=0.010)和吸烟(=0.025)会影响重症监护室的治疗,但与患者的精神障碍没有关联。患者的精神障碍会使开放性损伤的诊断复杂化。有效而及时的治疗要求专业人员能够同时识别患者的心理健康挑战和正在发展的 OI。
{"title":"Severe odontogenic infections in patients with mental disorders—the challenge of ineffective initial treatment","authors":"Satu Manninen BDS, Johanna Snäll MD DDS PhD, Tero Puolakkainen DDS PhD, Aleksi Haapanen DDS PhD","doi":"10.1016/j.oooo.2024.08.002","DOIUrl":"https://doi.org/10.1016/j.oooo.2024.08.002","url":null,"abstract":"This study clarified possible delays and deficiencies in severe odontogenic infection (OI) treatment in patients with mental disorders. Data of hospitalized patients with severe OI were evaluated retrospectively. The outcome variable was preceding health care visits prior to hospitalization. The primary predictor was patient's mental disorder. Explanatory variables were age, sex, smoking, heavy alcohol use, immunocompromised disease or medication, and time span from beginning of symptoms to hospitalization. Also, factors leading to intensive care unit (ICU) care were evaluated. Preceding visits prior to hospitalization were found in 61 (35.5%) out of 172 patients with OI. In total, 27 patients (15.7%) had a current mental disorder, more commonly in women (26.0%) than in men (8.1%) ( = .001). Patients with mental disorders had preceding health care visits related to the current infection notably more often than patients without recent psychiatric history (51.9% vs. 32.4%), = .053. Patient-related treatment delay remained nonsignificant. Heavy alcohol use ( = .010) and smoking ( = .025) predicted ICU treatment, but no association with patient's mental disorder was found. A patient's mental disorder can complicate diagnosis of OI. Effective and timely treatment requires the professional's ability to simultaneously identify the patient's mental health challenges and progressing OI.","PeriodicalId":501075,"journal":{"name":"Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142185691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Illicit cocaine and opioid drug-related maxillofacial trauma: a 10-year review of a state-wide database of all hospitals admissions 与非法可卡因和阿片类药物有关的颌面部创伤:对全州所有医院入院数据库的十年回顾
Pub Date : 2024-08-05 DOI: 10.1016/j.oooo.2024.07.013
Vincent Tran BDS, Michael Qiu BDS MBBS FRACDS (OMS), Santosh Kumar Tadakamadla PhD BDS MDS PGD-HP FHEA MRACDS (DPH), Kai Lee PhD BDSc MBBS MMedSc FRACDS (OMS)
The aim of this study was to investigate the characteristics of illicit cocaine and opioid drug-related facial trauma and determine whether the presence of cocaine or opioid drug use in facial trauma patients influenced the cause of injury, morbidity, or management. A retrospective observational cohort study was performed using records from a state-wide database of all patients who presented to a Victorian hospital with a facial fracture between 2004 and 2014. Data collected included demographics, concomitant opioid and cocaine use, mechanism of injury, facial injuries, and management. Statistical analysis was done using chi-square test, Student's tests, binary logistic regression analysis, and multivariable linear regression analysis. Results were considered statistically significant if < .05. A total of 54,613 patient presentations for facial trauma were analyzed with 363 patients in the cocaine and opioid-related group, and 54,250 patients in the nondrug-related group. Patients with illicit drug use were more likely to have facial fractures caused by interpersonal violence when compared with nondrug users (47.9% vs 23.5%, OR = 2.23, < .001). Opioid and cocaine users had 0.3 more total fractures per presentation, which included more midface and skull fractures, and more facial lacerations ( < .001). There was no statistically significant difference in the need for surgical management between the two groups. Opioid and cocaine affected patients also on average had a longer hospital stay of 3.4 days and required 0.9 more allied health inputs during their admission when compared with nondrug users ( < .05). This effect was similarly reflected when controlling for confounding variables ( < .001). Concomitant cocaine or opioid use in facial trauma patients leads to more violence-related injuries with higher morbidity and healthcare costs.
本研究旨在调查非法可卡因和阿片类药物相关面部创伤的特征,并确定面部创伤患者使用可卡因或阿片类药物是否会影响受伤原因、发病率或治疗。我们利用全州数据库中的记录开展了一项回顾性观察队列研究,该数据库收录了 2004 年至 2014 年间因面部骨折前往维多利亚州一家医院就诊的所有患者。收集的数据包括人口统计学特征、同时使用阿片类药物和可卡因的情况、受伤机制、面部损伤和处理方法。统计分析采用卡方检验、学生检验、二元逻辑回归分析和多变量线性回归分析。如果结果小于 0.05,则认为具有统计学意义。共分析了 54,613 名面部创伤患者,其中可卡因和阿片类药物相关组有 363 名患者,非药物相关组有 54,250 名患者。与非吸毒者相比,使用非法药物的患者更有可能因人际暴力而导致面部骨折(47.9% vs 23.5%,OR = 2.23,< .001)。阿片类药物和可卡因使用者每次发病时的骨折总数比其他人多0.3例,其中包括更多的中面部和颅骨骨折,以及更多的面部撕裂伤(< .001)。两组患者在手术治疗需求方面没有明显的统计学差异。与非吸毒者相比,受阿片类药物和可卡因影响的患者平均住院时间延长了3.4天,入院期间需要的专职医疗投入增加了0.9 ( < .05)。在控制了混杂变量后,这一影响也得到了类似的反映(< .001)。面部外伤患者同时使用可卡因或阿片类药物会导致更多与暴力相关的伤害,并带来更高的发病率和医疗费用。
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引用次数: 0
IMMUNOEXPRESSION OF HSP27 IN DENTIGEROUS CYSTS AND ODONTOGENIC KERATOCYSTS. 牙源性角化囊肿和牙源性角化囊肿中 hsp27 的免疫表达。
Pub Date : 2024-06-01 DOI: 10.1016/j.oooo.2023.12.653
N. Silva, Gustavo Borba Dias, Emily Ricelly da Silva Oliveira, Débora Frota Colares, Rodrigo Porpino Mafra, É. D. da Silveira, M. Miguel
{"title":"IMMUNOEXPRESSION OF HSP27 IN DENTIGEROUS CYSTS AND ODONTOGENIC KERATOCYSTS.","authors":"N. Silva, Gustavo Borba Dias, Emily Ricelly da Silva Oliveira, Débora Frota Colares, Rodrigo Porpino Mafra, É. D. da Silveira, M. Miguel","doi":"10.1016/j.oooo.2023.12.653","DOIUrl":"https://doi.org/10.1016/j.oooo.2023.12.653","url":null,"abstract":"","PeriodicalId":501075,"journal":{"name":"Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology","volume":"2 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141410046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CLINICOPATHOLOGICAL ANALYSIS OF CALCIFYING ODONTOGENIC CYSTS: A MULTICENTER RETROSPECTIVE STUDY. 钙化性牙源性囊肿的临床病理分析:多中心回顾性研究。
Pub Date : 2024-06-01 DOI: 10.1016/j.oooo.2023.12.712
H. Bezerra, Ana Luiza Oliveira Corrêa Roza, V. Cruz, W. V. van Heerden, M. Romañach, P. Vargas, D. Perez
{"title":"CLINICOPATHOLOGICAL ANALYSIS OF CALCIFYING ODONTOGENIC CYSTS: A MULTICENTER RETROSPECTIVE STUDY.","authors":"H. Bezerra, Ana Luiza Oliveira Corrêa Roza, V. Cruz, W. V. van Heerden, M. Romañach, P. Vargas, D. Perez","doi":"10.1016/j.oooo.2023.12.712","DOIUrl":"https://doi.org/10.1016/j.oooo.2023.12.712","url":null,"abstract":"","PeriodicalId":501075,"journal":{"name":"Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology","volume":"31 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141404183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
THE ROLE OF THE DENTIST IN THE HOSPITAL IN DIAGNOSIS AND MANAGEMENT OF HEMATOLOGICALLY BASED DISORDERS. 医院中的牙医在诊断和治疗血液病方面的作用。
Pub Date : 2024-06-01 DOI: 10.1016/j.oooo.2023.12.471
Marcos Altyeres Coelho Vasconcelos, A. R. de Camargo, L. J. Grando, Marcos Phelipe Araújo Andrade Alves, Everton Thiago Luz, Maria Victória Feijó Echevenguá, M. Lisboa
{"title":"THE ROLE OF THE DENTIST IN THE HOSPITAL IN DIAGNOSIS AND MANAGEMENT OF HEMATOLOGICALLY BASED DISORDERS.","authors":"Marcos Altyeres Coelho Vasconcelos, A. R. de Camargo, L. J. Grando, Marcos Phelipe Araújo Andrade Alves, Everton Thiago Luz, Maria Victória Feijó Echevenguá, M. Lisboa","doi":"10.1016/j.oooo.2023.12.471","DOIUrl":"https://doi.org/10.1016/j.oooo.2023.12.471","url":null,"abstract":"","PeriodicalId":501075,"journal":{"name":"Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology","volume":"28 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141403931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
IMMUNOTHERAPY WITH NATURAL COMPOUNDS IN HEAD AND NECK CANCER: A LITERATURE REVIEW. 头颈癌的天然化合物免疫疗法:文献综述。
Pub Date : 2024-06-01 DOI: 10.1016/j.oooo.2023.12.742
Ludmilla Dos Reis Silva, Anna Torrezani, Wigney Júnior Carvalho Gonzaga, Belmiro Ferreira Neves Neto, Winicius Arildo Ferreira Araujo, Vinícius Gonçalves de Souza, Carla Silva Siqueira Miranda
{"title":"IMMUNOTHERAPY WITH NATURAL COMPOUNDS IN HEAD AND NECK CANCER: A LITERATURE REVIEW.","authors":"Ludmilla Dos Reis Silva, Anna Torrezani, Wigney Júnior Carvalho Gonzaga, Belmiro Ferreira Neves Neto, Winicius Arildo Ferreira Araujo, Vinícius Gonçalves de Souza, Carla Silva Siqueira Miranda","doi":"10.1016/j.oooo.2023.12.742","DOIUrl":"https://doi.org/10.1016/j.oooo.2023.12.742","url":null,"abstract":"","PeriodicalId":501075,"journal":{"name":"Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology","volume":"43 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141406645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
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