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Whole blood: total blood product ratio impacts survival in injured children. 全血:全血制品比例对受伤儿童存活率的影响。
Pub Date : 2024-04-30 DOI: 10.1097/ta.0000000000004362
Erin Feeney, Katrina M Morgan, Philip C Spinella, Barbara A Gaines, Christine M Leeper
Some studies in both children and adults have shown a mortality benefit for the use of low titer group O whole blood (LTOWB) compared to component therapy for traumatic resuscitation. Although LTOWB is not widely available at pediatric trauma centers, its use is increasing. We hypothesized that in children who received whole blood after injury, the proportion of whole blood in relation to the total blood product resuscitation volume would impact survival.
一些针对儿童和成人的研究表明,与创伤复苏中的成分疗法相比,使用低滴度 O 组全血(LTOWB)可降低死亡率。尽管低滴度 O 组全血在儿科创伤中心并不普及,但其使用率正在不断上升。我们假设,在受伤后接受全血的儿童中,全血与血液制品复苏总量的比例将影响存活率。
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引用次数: 0
Characterizing Trauma Patients with Delays in Orthopaedic Process Measures. 用矫形过程测量法描述有延迟的创伤患者的特征。
Pub Date : 2024-04-30 DOI: 10.1097/ta.0000000000004346
Nishant Gohel, Pranav Khambete, Laura Gerhardinger, Anna N Miller, Philip Wolinsky, Molly Jarman, John W Scott, Rahul Vaidya, Mark R Hemmila, Bryant W Oliphant
Early operative intervention in orthopaedic injuries is associated with decreased morbidity and mortality. Relevant process measures (e.g. femoral shaft fixation <24 hours) are used in trauma quality improvement programs to evaluate performance. Currently, there is no mechanism to account for patients who are unable to undergo surgical intervention (i.e. physiologically unstable). We characterized the factors associated with patients who did not meet these orthopaedic process measures.
骨科损伤的早期手术干预与发病率和死亡率的降低有关。在创伤质量改进计划中,相关的流程措施(如股骨干固定术<24小时)被用于评估绩效。目前,还没有一种机制可以对无法接受手术治疗的患者(即生理状态不稳定的患者)进行解释。我们对未达到这些骨科流程措施要求的患者的相关因素进行了分析。
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引用次数: 0
Characteristics of Firearm Injury by Injury Intent: The Need for Tailored Interventions. 按伤害意图划分的火器伤害特征:需要有针对性的干预措施。
Pub Date : 2024-04-24 DOI: 10.1097/TA.0000000000004344
Shelbie D Kirkendoll, Ashley B. Hink, Deborah A Kuhls, F. P. Rivara, Joseph V Sakran, Lauren L. Agoubi, Alex Winchester, Jacy Richards, Christopher J. Hoeft, Bhavin Patel, Holly N Michaels, A. Nathens
INTRODUCTIONWhile the U.S. has high quality data on firearm-related deaths, less information is available on those who arrive at trauma centers alive, especially those discharged from the emergency department. This study sought to describe characteristics of patients arriving to trauma centers alive following a firearm injury, postulating that significant differences in firearm injury intent might provide insights into injury prevention strategies.METHODSThis was a multi-center prospective cohort study of patients treated for firearm-related injuries at 128 U.S. trauma centers from 3/2021-2/2022. Data collected included patient-level sociodemographic, injury and clinical characteristics, community characteristics, and context of injury. The outcome of interest was the association between these factors and the intent of firearm injury. Measures of urbanicity, community distress, and strength of state firearm laws were utilized to characterize patient communities.RESULTS15,232 patients presented with firearm-related injuries across 128 centers in 41 states. Overall, 9.5% of patients died, and deaths were more common among law enforcement and self-inflicted (SI) firearm injuries (80.9% and 50.5%, respectively). These patients were also more likely to have a history of mental illness. SI firearm injuries were more common in older White men from rural and less distressed communities, whereas firearm assaults were more common in younger, Black men from urban and more distressed communities. Unintentional injuries were more common among younger patients and in states with lower firearm safety grades whereas law enforcement-related injuries occurred most often in unemployed patients with a history of mental illness.CONCLUSIONSInjury, clinical, sociodemographic, and community characteristics among patients injured by a firearm significantly differed between intents. With the goal of reducing firearm-related deaths, strategies and interventions need to be tailored to include community improvement and services that address specific patient risk factors for firearm injury intent.LEVEL OF EVIDENCELevel III, Prognostic/Epidemiological.
引言虽然美国拥有与枪支相关的高质量死亡数据,但关于那些活着到达创伤中心的患者,尤其是那些从急诊科出院的患者的信息却较少。本研究试图描述在枪支伤害后活着到达创伤中心的患者的特征,假设枪支伤害意图的显著差异可能会为伤害预防策略提供启示。收集的数据包括患者的社会人口学特征、受伤和临床特征、社区特征以及受伤背景。关注的结果是这些因素与枪支伤害意图之间的关联。结果41个州的128个中心共收治了15232名枪支相关伤害患者。总体而言,9.5%的患者死亡,其中执法人员枪支伤害和自残枪支伤害的死亡人数较多(分别为80.9%和50.5%)。这些患者也更有可能有精神病史。自残式枪伤更常见于来自农村和不太贫困社区的老年白人男性,而枪支袭击则更常见于来自城市和较贫困社区的年轻黑人男性。意外伤害在年轻患者和枪支安全等级较低的州更为常见,而与执法相关的伤害则多发生在有精神病史的失业患者身上。为了减少与枪支相关的死亡,需要对战略和干预措施进行调整,以包括针对枪支伤害意图的特定患者风险因素的社区改善和服务。
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引用次数: 0
Response to the letter to the editor for our article entitled "A Pseudo-dilemma: Are we over-diagnosing and over-treating traumatic splenic intraparenchymal pseudoaneurysms?" 对我们题为 "一个伪难题:我们是否过度诊断和治疗了外伤性脾动脉内假性动脉瘤?
Pub Date : 2024-04-16 DOI: 10.1097/TA.0000000000004360
M. Harfouche, Rishi Kundi, T. Scalea
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引用次数: 0
Letter to the Editor - External validation of novel Revised Intensity Battle Score and comparison of static rib fracture scoring systems. 致编辑的信 - 新型修订强度战斗评分的外部验证以及肋骨骨折静态评分系统的比较。
Pub Date : 2024-04-16 DOI: 10.1097/TA.0000000000004333
Ceri Battle
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引用次数: 0
Direct red blood cell effect on thrombosis is dependent on the interaction of tissue factor and calcium with membrane phosphatidylserine. 红细胞对血栓形成的直接影响取决于组织因子和钙与膜磷脂酰丝氨酸的相互作用。
Pub Date : 2024-04-12 DOI: 10.1097/ta.0000000000004340
Adam D Price, Ryan C Chae, Taylor E Wallen, Ellen R Becker, Matthew R Baucom, Rebecca Schuster, Lisa England, Timothy A Pritts, Michael D Goodman
Prior literature has implicated Red Blood Cells (RBCs) in the initiation of thrombosis and suggests that post-transfusion hypercoagulability may occur secondary to the effects of RBCs. Elevated serum tissue factor is a known sequelae of acute trauma. Phosphatidylserine is a pro-thrombotic phospholipid present within the RBC cell membrane. We hypothesized that RBC aggregation is dependent on the interaction between RBC membrane bound (exposed) PS, extracellular calcium, and tissue factor.
先前的文献指出红细胞(RBC)与血栓形成的起因有关,并认为输血后高凝状态可能继发于红细胞的影响。血清组织因子升高是已知的急性创伤后遗症。磷脂酰丝氨酸是一种存在于红细胞细胞膜内的促血栓形成磷脂。我们假设 RBC 的聚集取决于 RBC 膜结合(暴露)的 PS、细胞外钙和组织因子之间的相互作用。
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引用次数: 0
Should Soldiers Take Oral Tranexamic Acid Before Going into Battle? 士兵是否应该在上战场前口服氨甲环酸?
Pub Date : 2024-04-10 DOI: 10.1097/ta.0000000000004343
Nicolas Cazes, Simon-Pierre Corcostegui, Steven Lovi, Emeric Romary, Vincent Desrobert, Lionel Lidzborski, Clément Derkenne
Tranexamic acid is an inexpensive antifibrinolytic treatment that reduces morbidity and mortality in civilian and military trauma patients. It must be administered within 3 hours of the injury, and its efficacy is greater the earlier it is given. It is already used preventively in the civilian environment in a number of indications to reduce bleeding and bleeding-related mortality. We wondered about the potential benefits of preventive oral administration of tranexamic acid prior to an assault for military personnel with a potential risk of injury.
氨甲环酸是一种廉价的抗纤维蛋白溶解治疗药物,可降低平民和军事创伤患者的发病率和死亡率。氨甲环酸必须在受伤后 3 小时内使用,而且越早使用疗效越好。在民用环境中,它已被用于多种适应症的预防性治疗,以减少出血和与出血相关的死亡率。我们想知道,对有潜在受伤风险的军事人员来说,在攻击前预防性口服氨甲环酸有哪些潜在益处。
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引用次数: 0
Response to the letter to the editor for our article entitled "A Pseudo-dilemma: Are we over-diagnosing and over-treating traumatic splenic intraparenchymal pseudoaneurysms?" 对我们题为 "一个伪难题:我们是否过度诊断和治疗了外伤性脾动脉内假性动脉瘤?
Pub Date : 2024-04-10 DOI: 10.1097/TA.0000000000004359
M. Harfouche, Rishi Kundi, T. Scalea
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引用次数: 0
Comparison of Law Enforcement Officer versus Emergency Medical Services Placed Tourniquets. 执法人员与紧急医疗服务人员放置止血带的比较。
Pub Date : 2024-04-10 DOI: 10.1097/ta.0000000000004349
Dhara Shukla, Geoff Shapiro, E Reed Smith, Babak Sarani
Tourniquet (TQ) use for hemorrhage control is a core skill for many law enforcement officers (LEO) and all emergency medical services (EMS) providers. However, LEO TQ training is not as intensive as EMS. Overuse of TQ can result in over triage. We hypothesize that LEO are more liberal than EMS with TQ placement.
使用止血带(TQ)控制出血是许多执法人员(LEO)和所有紧急医疗服务(EMS)提供者的核心技能。但是,执法人员止血带培训的强度不如急救医疗服务人员。过度使用 TQ 可能会导致过度分流。我们假设,执法人员比急救医疗人员更善于使用 TQ。
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引用次数: 0
CONTEMPORARY DIAGNOSIS AND MANAGEMENT OF COLORECTAL INJURIES: WHAT YOU NEED TO KNOW. 结肠直肠损伤的当代诊断和管理:你需要知道的。
Pub Date : 2024-04-10 DOI: 10.1097/ta.0000000000004352
Adam Fields, Ali Salim
Colorectal injuries are commonly encountered by trauma surgeons. The management of colorectal injuries has evolved significantly over the past several decades, beginning with wartime experience and subsequently refining with prospective randomized studies. Colon injuries were initially nonoperative, evolved towards fecal diversion for all, then became anatomic based with resection and primary anastomosis with selective diversion, and now primary repair, resection with primary anastomosis, or delayed anastomosis after damage control laparotomy are all commonplace. Rectal injuries were also initially considered non-operative until diversion came into favor. Diversion in addition to direct repair, presacral drain placement, and distal rectal washout became the gold standard for extraperitoneal rectal injuries until drainage and washout fell out of favor. Despite a large body of evidence, there remains debate on the optimal management of some colorectal injuries. This article will focus on how to diagnose and manage colorectal injuries. The aim of this review is to provide an evidence-based summary of the contemporary diagnosis and management of colorectal injuries.
结肠直肠损伤是创伤外科医生经常遇到的问题。在过去的几十年中,结肠直肠损伤的治疗方法发生了显著的变化,最初是根据战时经验,随后通过前瞻性随机研究加以改进。结肠损伤最初是不进行手术的,后来逐渐发展到对所有患者进行粪便转流,再后来发展到以解剖为基础的切除术和选择性转流的初端吻合术,而现在,初端修复术、切除加初端吻合术或损伤控制腹腔手术后的延迟吻合术都已司空见惯。直肠损伤最初也被认为是非手术性的,直到转流术的出现。除了直接修补术、骶前引流管置入术和直肠远端冲洗术外,转流术也成为腹膜外直肠损伤的金标准,直到引流和冲洗术不再受青睐。尽管有大量证据表明,对于某些结肠直肠损伤的最佳处理方法仍存在争议。本文将重点讨论如何诊断和处理结直肠损伤。本综述旨在对当代结直肠损伤的诊断和处理进行循证总结。
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The Journal of Trauma and Acute Care Surgery
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