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Pharmaceutical innovation collaboration, evaluation, and matching 医药创新合作、评估和匹配
IF 3.4 2区 经济学 Q1 ECONOMICS Pub Date : 2024-09-11 DOI: 10.1016/j.jhealeco.2024.102922

This paper theoretically studies pharmaceutical innovation collaborations, where heterogeneous firms compete for heterogeneous academics. At an interim stage, the firm evaluates the project, which allows it to monitor academics and decide whether to terminate the project to avoid the loss from a future failure. This paper explores the contract, project termination strategy, and collaboration matching. The firm’s innovation strategy (exploitations or explorations) determines the evaluation structure, which may affect the market equilibrium. By considering different innovation strategies, this paper shows that in each case, the equilibrium matching is unique (either positive or negative assortative). Consequently, the chosen innovation strategy plays a pivotal role in shaping equilibrium matching outcomes. These findings provide theoretical insights into pharma-academic alliances, shed light on the observed positive or negative assortative properties in the market, and advocate for the consideration of innovation strategies and evaluation structures in future research endeavors. Moreover, this paper also provides several empirical and policy implications.

本文从理论上研究了医药创新合作,在这种合作中,异质企业争夺异质学者。在中期阶段,企业会对项目进行评估,从而对学者进行监督,并决定是否终止项目,以避免未来失败带来的损失。本文探讨了合同、项目终止策略和合作匹配。企业的创新战略(开发或探索)决定了评估结构,而评估结构可能会影响市场均衡。通过考虑不同的创新战略,本文表明,在每种情况下,均衡匹配都是唯一的(要么是正向匹配,要么是负向匹配)。因此,所选择的创新战略在形成均衡匹配结果方面起着举足轻重的作用。这些发现提供了对医药-学术联盟的理论见解,揭示了市场中观察到的正向或负向同配特性,并倡导在未来的研究工作中考虑创新战略和评估结构。此外,本文还提供了一些经验和政策方面的启示。
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引用次数: 0
Paying for advance care planning in medicare: Impacts on care and spending near end of life 在医疗保险中支付预先护理计划的费用:对临终护理和支出的影响
IF 3.4 2区 经济学 Q1 ECONOMICS Pub Date : 2024-09-06 DOI: 10.1016/j.jhealeco.2024.102921

Spending at end of life (EOL) accounts for a large and growing share of healthcare expenditures in the US, and often reflects aggressive care with questionable value for dying patients. Using a novel instrumental variables approach, we conduct the first study on the causal effect of Medicare reimbursement for advance care planning (ACP)—the process of discussing and recording patient preferences for goals of care—on care utilization, spending, and mortality outcomes for critically ill Medicare patients. We find that billed ACP services substantially increase hospice use and hospice spending within a year, accompanied by corresponding increase in one-year mortality. The impacts of ACP services on hospice use and spending are especially prominent among patients with dementia and those of lower socioeconomic status. Among decedents, death is significantly less likely to occur in the hospital, and total and inpatient spending within the last 30 days of life fall significantly. Our findings suggest that paying for ACP services can be effective in improving hospice use for critically ill Medicare patients, with the (possibly intended) consequence of increased one-year mortality.

在美国,生命末期(EOL)的支出占医疗支出的比例很大,而且还在不断增长,这往往反映出积极的护理对垂死病人的价值值得怀疑。我们使用一种新颖的工具变量方法,首次研究了医疗保险对预先护理计划(ACP)的补偿的因果效应,预先护理计划是指讨论和记录患者对护理目标的偏好的过程,它对医疗保险重症患者的护理利用率、支出和死亡率结果都有影响。我们发现,开具账单的 ACP 服务在一年内大幅增加了临终关怀的使用率和临终关怀的支出,同时一年的死亡率也相应增加。ACP 服务对临终关怀使用和支出的影响在痴呆症患者和社会经济地位较低的患者中尤为突出。在死者中,在医院死亡的可能性明显降低,生命最后 30 天内的总支出和住院费用也显著下降。我们的研究结果表明,为 ACP 服务付费可以有效改善医疗保险重症患者的安宁疗护使用情况,其结果(可能是预期的)是增加了一年的死亡率。
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引用次数: 0
Hospital competition when patients learn through experience 患者从经验中学习时的医院竞争
IF 3.4 2区 经济学 Q1 ECONOMICS Pub Date : 2024-09-01 DOI: 10.1016/j.jhealeco.2024.102920

We study competing hospitals’ incentives for quality provision in a dynamic setting where healthcare is an experience good. In our model, the utility a patient derives from choosing a particular provider depends on a subjective component specific to the match between the patient and the provider, which can only be learned through experience. We find that the experience-good nature of healthcare can either reinforce or dampen the demand responsiveness to quality and the hospitals’ incentives for quality provision, depending on two key factors: the shape of the distribution of match-specific utilities and the cost relationship between quality provision and treatment volume. We establish conditions under which ignoring the experience dimension of healthcare leads to inaccurate assessments of the competitiveness of hospital markets.

我们研究了在医疗保健是一种经验商品的动态环境下,竞争医院提供优质医疗服务的激励机制。在我们的模型中,患者从选择特定医疗服务提供者中获得的效用取决于患者与医疗服务提供者之间匹配的主观因素,而这种因素只能通过经验获得。我们发现,医疗保健的 "经验好 "性质既可以加强也可以削弱对质量的需求反应和医院提供质量的动力,这取决于两个关键因素:匹配特定效用的分布形状以及质量提供与治疗量之间的成本关系。我们确定了忽略医疗保健的经验维度会导致对医院市场竞争力评估不准确的条件。
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引用次数: 0
Do e-cigarette retail licensure laws reduce youth tobacco use? 电子烟零售许可法能减少青少年烟草使用吗?
IF 3.4 2区 经济学 Q1 ECONOMICS Pub Date : 2024-08-22 DOI: 10.1016/j.jhealeco.2024.102919

E-cigarette licensure laws (ELLs) require retailers to obtain a state license to sell e-cigarettes over the counter. This study is the first to comprehensively explore the effect of ELL adoption on youth tobacco product use. Using data from the State Youth Risk Behavior Survey (YRBS) and a difference-in-differences approach, we find no evidence that ELL adoption reduces youth ENDS use. The precision of our estimates allows us to rule out, with 95 % confidence, ELL-induced declines in prior-month, frequent, and everyday youth ENDS use of more than 0.7, 0.3, and 0.4 percentage points, respectively. The pattern of null findings persists when we examine ELLs that impose higher penalties for retailer non-compliance, higher renewable licensure fees, and criminal in addition to civil penalties. We conclude that ELLs have only limited success in curbing access to ENDS among youths.

电子烟许可法(ELL)要求零售商必须获得州政府颁发的许可证才能在柜台销售电子烟。本研究首次全面探讨了采用 ELL 对青少年烟草制品使用的影响。利用州青少年风险行为调查(YRBS)的数据和差分法,我们没有发现任何证据表明采用 ELL 会减少青少年使用 ENDS。我们估算的精确度使我们能够以 95% 的置信度排除 ELL 引起的青少年上月、经常和日常 ENDS 使用率分别下降超过 0.7、0.3 和 0.4 个百分点的可能性。当我们研究对零售商违规行为处以更高的处罚、收取更高的可续期许可费以及除民事处罚外还处以刑事处罚的 ELL 时,结果依然为空。我们的结论是,电子学习法律在遏制青少年接触ENDS方面成效有限。
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引用次数: 0
Health insurance, agricultural production and investments 医疗保险、农业生产和投资
IF 3.4 2区 经济学 Q1 ECONOMICS Pub Date : 2024-08-08 DOI: 10.1016/j.jhealeco.2024.102918

We study the effects of health insurance coverage on agricultural production decisions, examining the causal relationships by exploiting a health care reform and providing a theoretical framework to elucidate underlying mechanisms. We find that the reform led to long-run increases in total cultivation investments and output, accompanied by a shift in households’ cultivation portfolio towards riskier crops. We explain these findings using a model of agricultural investment, highlighting the important roles of health insurance in mitigating background medical expenditure risks and enhancing health. We also find that the reform improved households’ financial well-being through reduced debts and defaults on loans.

我们研究了医疗保险对农业生产决策的影响,通过利用医疗改革来检验因果关系,并提供了一个理论框架来阐明内在机制。我们发现,改革导致了种植业总投资和产出的长期增长,并伴随着家庭种植组合向风险较高作物的转移。我们利用农业投资模型解释了这些发现,并强调了医疗保险在降低背景医疗支出风险和提高健康水平方面的重要作用。我们还发现,改革通过减少债务和拖欠贷款改善了家庭的财务状况。
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引用次数: 0
Investigating the complexity of naloxone distribution: Which policies matter for pharmacies and potential recipients 调查纳洛酮分发的复杂性:哪些政策对药店和潜在接受者至关重要
IF 3.4 2区 经济学 Q1 ECONOMICS Pub Date : 2024-07-17 DOI: 10.1016/j.jhealeco.2024.102917

Despite efforts to expand naloxone access, opioid-related overdoses remain a significant contributor to mortality. We study state efforts to expand naloxone distribution through pharmacies by reducing the non-monetary costs to prescribers, dispensers, and/or potential recipients of naloxone. We find that laws that only address liability costs have small and insignificant effects on the volume of naloxone dispensed through pharmacies. In contrast, we estimate large effects of laws removing the need for patients to obtain prescriptions from traditional prescribers (e.g., primary care physicians): laws authorizing non-patient-specific prescription distribution and laws granting pharmacists prescriptive authority. We test whether areas designated as primary care shortage areas—where it would be costlier to obtain a prescription—were disproportionately impacted. Shortage areas experienced sharper growth in pharmacy naloxone dispensing in states adopting prescriptive authority policies. These gains were primarily due to those facing low out-of-pocket costs, suggesting that price barriers also must be addressed to increase naloxone purchases.

尽管各州努力扩大纳洛酮的使用范围,但与阿片类药物相关的用药过量仍是导致死亡的重要原因。我们研究了各州通过降低处方者、配药者和/或纳洛酮潜在接受者的非货币成本来扩大纳洛酮通过药店配药的努力。我们发现,只涉及责任成本的法律对通过药店发放纳洛酮的数量影响很小,而且不显著。与此相反,我们估算出了免除患者从传统处方者(如初级保健医生)处获得处方的法律所产生的巨大影响:授权非特定患者处方分配的法律和授予药剂师处方权的法律。我们检验了被指定为初级保健短缺地区的地区(在这些地区获取处方的成本更高)是否受到了不成比例的影响。在采用处方权政策的州,短缺地区的纳洛酮药房配药量增长更快。这些增长主要归功于那些自付费用较低的地区,这表明要增加纳洛酮的购买量,还必须解决价格障碍。
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引用次数: 0
Financial incentives for sanitation take-up: A randomized control trial in rural Vietnam 促进卫生设施使用的财政激励措施:越南农村随机对照试验
IF 3.4 2区 经济学 Q1 ECONOMICS Pub Date : 2024-07-07 DOI: 10.1016/j.jhealeco.2024.102916
Cuong Viet Nguyen , Tung Duc Phung

This study assesses the impact of financial incentives on hygienic latrine ownership by poor/near-poor households in Vietnam. Rural communes were randomly assigned to a control group and three treatment arm groups: (T1) a rebate for households that installed a hygienic latrine; (T2) a financial reward for commune governments if the proportion of hygienic latrines in their commune increased by 30 percentage points; (T3) both a household rebate and a commune reward. We find a strong and positive effect from the household rebate (treatment arms 1 and 3) but an insignificant effect from the commune reward (treatment arm 2) on household ownership of a septic tank latrine. Our analysis provides suggestive evidence that microcredit is a channel through which a rebate encourages the installation of septic tank latrines. We also find that treatment arm 3 increases people's knowledge regarding sanitation and the availability of water and soap for handwashing within households.

本研究评估了经济激励措施对越南贫困/近乎贫困家庭拥有卫生厕所的影响。农村乡镇被随机分配到一个对照组和三个处理组:(T1)对安装卫生厕所的家庭给予回扣;(T2)如果乡镇的卫生厕所比例提高了 30 个百分点,乡镇政府将获得财政奖励;(T3)同时给予家庭回扣和乡镇奖励。我们发现,家庭返利(处理方案 1 和 3)对家庭拥有化粪池厕所有很强的积极影响,但乡镇奖励(处理方案 2)对家庭拥有化粪池厕所的影响并不显著。我们的分析提供了提示性证据,表明小额贷款是鼓励安装化粪池厕所的一个渠道。我们还发现,治疗方案 3 提高了人们对环境卫生的认识,以及家庭内洗手用水和肥皂的可用性。
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引用次数: 0
Housing wealth, fertility and children's health in China: A regression discontinuity design 中国的住房财富、生育率和儿童健康:回归不连续设计
IF 3.4 2区 经济学 Q1 ECONOMICS Pub Date : 2024-07-06 DOI: 10.1016/j.jhealeco.2024.102915
Geer Ang , Ya Tan , Yingjia Zhai , Fan Zhang , Qinghua Zhang

This paper examines the influence of housing wealth on fertility outcomes through a regression discontinuity design based on a 2006 Chinese housing-market policy. Our analysis reveals that the positive impact of this policy on housing wealth significantly enhances the likelihood of fertility by 7.3 %. Our result implies that a 1 % increase in housing wealth can raise the fertility rate by 0.18 %. Furthermore, we observe that children born subsequent to the positive housing wealth shock exhibit improved health, not only at birth but also over the long term. Lastly, we present suggestive evidence suggesting that both parental pre-birth time allocation and parental health may help explain the documented positive effects of housing wealth on fertility rates.

本文通过基于 2006 年中国住房市场政策的回归不连续设计,研究了住房财富对生育结果的影响。我们的分析表明,该政策对住房财富的积极影响显著提高了 7.3% 的生育可能性。我们的结果意味着,住房财富每增加 1%,生育率就会提高 0.18%。此外,我们还观察到,在住房财富受到积极冲击后出生的儿童不仅在出生时,而且在长期内都会表现出健康状况的改善。最后,我们提出了一些提示性证据,表明父母出生前的时间分配和父母的健康状况可能有助于解释所记录的住房财富对生育率的积极影响。
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引用次数: 0
Nudging the nudger: Performance feedback and organ donor registrations 点拨点拨者:绩效反馈与器官捐献登记
IF 3.4 2区 经济学 Q1 ECONOMICS Pub Date : 2024-07-03 DOI: 10.1016/j.jhealeco.2024.102914

In a randomized controlled trial conducted in three waves over 2.5 years and involving nearly 700 customer-service representatives (CSRs) from a Canadian government service agency, we studied how providing CSRs with repeated performance feedback, with or without peer comparison, affected their subsequent organ donor registration rates. The feedback resulted in a 25 % increase in daily signups compared to otherwise equivalent encouragements and reminders. Adding benchmark information about peer performance did not amplify or diminish this effect. We observed increased registration rates for both high and low performers. A post-intervention survey indicates that CSRs in all conditions found the information included in the treatments helpful and motivating, and that signing up organ donors makes their job more meaningful. We also found suggestive evidence that performance feedback with benchmark information was the most motivating and created the least pressure to perform.

在一项历时 2.5 年、分三轮进行、有近 700 名加拿大政府服务机构客户服务代表(CSR)参与的随机对照试验中,我们研究了在有或没有同行比较的情况下,向客户服务代表反复提供绩效反馈会如何影响他们随后的器官捐献登记率。与其他同等的鼓励和提醒相比,反馈使每日登记率提高了 25%。添加有关同行表现的基准信息并没有扩大或缩小这种影响。我们观察到,无论是表现好的还是表现差的,注册率都有所提高。干预后的调查显示,所有情况下的企业社会责任人都认为处理方法中包含的信息很有帮助和激励作用,并且登记器官捐献者让他们的工作更有意义。我们还发现,有提示性证据表明,包含基准信息的绩效反馈最能激发员工的积极性,也最不会给他们带来工作压力。
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引用次数: 0
Housing wealth, fertility and children's health in China: A regression discontinuity design. 中国的住房财富、生育率和儿童健康:回归不连续设计
IF 3.4 2区 经济学 Q1 ECONOMICS Pub Date : 2024-07-01 DOI: 10.2139/ssrn.4852579
Geer Ang, Ya Tan, Ying Zhai, Fan Zhang, Qinghua Zhang
This paper examines the influence of housing wealth on fertility outcomes through a regression discontinuity design based on a 2006 Chinese housing-market policy. Our analysis reveals that the positive impact of this policy on housing wealth significantly enhances the likelihood of fertility by 7.3 %. Our result implies that a 1 % increase in housing wealth can raise the fertility rate by 0.18 %. Furthermore, we observe that children born subsequent to the positive housing wealth shock exhibit improved health, not only at birth but also over the long term. Lastly, we present suggestive evidence suggesting that both parental pre-birth time allocation and parental health may help explain the documented positive effects of housing wealth on fertility rates.
本文通过基于 2006 年中国住房市场政策的回归不连续设计,研究了住房财富对生育结果的影响。我们的分析表明,该政策对住房财富的积极影响显著提高了 7.3% 的生育可能性。我们的结果意味着,住房财富每增加 1%,生育率就会提高 0.18%。此外,我们还观察到,在住房财富受到积极冲击后出生的儿童不仅在出生时,而且在长期内都会表现出健康状况的改善。最后,我们提出了一些提示性证据,表明父母出生前的时间分配和父母的健康状况可能有助于解释所记录的住房财富对生育率的积极影响。
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引用次数: 0
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Journal of Health Economics
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