Journal of Aapos最新文献

英文中文

Long-term outcomes of Ahmed glaucoma drainage device capsulectomies in pediatric glaucoma patients 小儿青光眼患者接受艾哈迈德青光眼引流装置囊切除术的长期疗效。

IF 1.2 4区医学 Q3 OPHTHALMOLOGY

Journal of Aapos

Pub Date : 2024-10-01 DOI: 10.1016/j.jaapos.2024.104002

Sharmila Segar MD , Amanda Ismail MD , Riya Shah BS , Chaesik Kim BSEE , Aditi Kappagantu BS , John Roarty MD

Purpose

To investigate the long-term outcomes associated with Ahmed glaucoma device capsulectomy in pediatric patients at a single institution over a period of nearly 10 years, from 2011 to 2021.

Methods

We retrospectively reviewed the medical records of pediatric glaucoma patients with FP-7 Ahmed glaucoma device capsulectomies performed by three surgeons. Surgical success was defined as post-capsulectomy IOP of <21 mm Hg at most recent follow-up without need for additional procedures, regardless of topical medications.

Results

A total of 22 capsulectomies of 22 eyes of 18 patients aged 1-17 years were reviewed. Median post-capsulectomy follow-up was 5.8 years. Etiologies of glaucoma were primary congenital glaucoma (50%), anterior segment dysgenesis (32%), Sturge-Weber syndrome (14%), and angle recession (5%). Pre-capsulectomy IOP was 30 ± 6.2 mm Hg, with first postoperative IOP of 15 ± 8.0 mm Hg. Surgical success was achieved with 5 capsulectomies (23%), with follow-up of 1.5-5.9 years. Post-capsulectomy complications included short-term hypotony in 1 eye (5%) and macular edema in 1 eye (5%). Eleven of 22 eyes (50%) had at least one repeat placement of Ahmed glaucoma device, with median time to repeat surgery of 80 months.

Conclusions

In pediatric glaucoma patients with glaucoma drainage device encapsulation, capsulectomy likely does not prevent additional surgery in most children over the long term, but may serve as a temporizing measure before other interventions.

目的：在2011年至2021年的近10年时间里，调查一家医疗机构为小儿患者实施艾哈迈德青光眼装置囊切除术的长期疗效：我们回顾性地查看了由三位外科医生实施的FP-7艾哈迈德青光眼器帽切除术的小儿青光眼患者的病历。手术成功的定义是，囊帽切除术后的眼压达到结果：共审查了 18 名 1-17 岁患者 22 只眼睛的 22 例帽状切除术。囊帽切除术后的中位随访时间为 5.8 年。青光眼的病因包括原发性先天性青光眼（50%）、前节发育不良（32%）、Sturge-Weber 综合征（14%）和角膜后退（5%）。囊袋切除术前的眼压为 30 ± 6.2 mm Hg，术后首次眼压为 15 ± 8.0 mm Hg。有 5 例眼帽切除术取得了手术成功（23%），随访时间为 1.5-5.9 年。眼帽切除术后并发症包括 1 只眼睛（5%）出现短期低眼压，1 只眼睛（5%）出现黄斑水肿。22只眼睛中有11只（50%）至少重复放置过一次艾哈迈德青光眼装置，重复手术的中位时间为80个月：结论：对于青光眼引流装置被包裹的小儿青光眼患者，囊帽切除术可能无法长期避免大多数患儿再次接受手术，但可以作为其他干预措施前的临时措施。

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引用次数: 0

The effect of age on congenital nasolacrimal duct obstruction probing and stent intubation outcomes in pediatric Down syndrome patients 年龄对小儿唐氏综合征患者先天性鼻泪管阻塞探查和支架插管结果的影响。

IF 1.2 4区医学 Q3 OPHTHALMOLOGY

Journal of Aapos

Pub Date : 2024-10-01 DOI: 10.1016/j.jaapos.2024.104010

Yulia Haraguchi BA , Zeina Salem MD , Noor Ghali MS , Arianne Zeng BS , Faruk H. Örge MD

Purpose

To examine the effect of age at time of congenital nasolacrimal duct obstruction (CNLDO) intervention on symptom resolution and reoperation rates in patients with Down syndrome (DS).

Methods

The medical records of patients with DS and CNLDO between 2012 and 2021 were reviewed retrospectively. Age at the time of first stent placement was utilized to categorize patients into age groups <3 and >3 years of age. Epiphora resolution at last office visit and restenting rate were used as outcome measures.

Results

A total of 49 patients with DS and CLNDO were identified between 2012 and 2021; of these, 17 had received surgical stent placement with appropriate follow-up. Epiphora resolution (X²₁ = 0.78, P = 0.33), restenting rate (X²₁ = 2.84, P = 0.09), cumulative stent duration (P = 0.33) and number of stent placement operations (P = 0.98) were not significantly different between the age groups. There was no significant difference between stent duration <1 year or >1 year with regard to epiphora resolution (X²₁ = 0.91, P = 0.34).

Conclusions

Success of stent placement and reoperation rates among patients with DS and CNLDO were not associated with age and duration of stent intubation. Intervention at later ages may still be beneficial for symptom resolution in patients with DS.

目的：研究先天性鼻泪管阻塞（CNLDO）干预时的年龄对唐氏综合征（DS）患者症状缓解和再次手术率的影响：方法：对2012年至2021年间唐氏综合征和先天性鼻泪管阻塞患者的病历进行回顾性研究。首次放置支架时的年龄被用来将患者划分为 3 岁年龄组。结果显示，共有 49 名 DS 和 CNLDO 患者接受了支架植入治疗：结果：2012 年至 2021 年间，共发现了 49 例 DS 和 CLNDO 患者；其中 17 例接受了手术支架置入并进行了适当的随访。不同年龄组的外虹膜消退率（X21=0.78，P=0.33）、再支架植入率（X21=2.84，P=0.09）、累计支架植入时间（P=0.33）和支架植入手术次数（P=0.98）无显著差异。支架持续时间 1 年与上睑下垂缓解程度无明显差异（X21 = 0.91，P = 0.34）：结论：DS和CNLDO患者的支架置入成功率和再次手术率与年龄和支架插管持续时间无关。结论：DS 和 CNLDO 患者的支架置入成功率和再次手术率与年龄和支架插管持续时间无关。

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引用次数: 0

Overlapping clinical features of persistent fetal vasculature and combined hamartoma of the retina and retinal pigment epithelium 胎儿持续性血管瘤与视网膜和视网膜色素上皮合并火腿肠瘤的临床特征重叠。

IF 1.2 4区医学 Q3 OPHTHALMOLOGY

Journal of Aapos

Pub Date : 2024-10-01 DOI: 10.1016/j.jaapos.2024.104012

Ece Ozdemir Zeydanli MD, FRCS(Ed) , Ahmet Yucel Ucgul MD, FRCS(Ed) , H. Tuba Atalay MD, FEBO , M. Elizabeth Hartnett MD, FASRS , Ehab El Rayes MD, FASRS , Huban Atilla MD, FEBO , Sengul Ozdek MD, FASRS

Purpose

To investigate cases exhibiting overlapping features of persistent fetal vasculature (PFV) and combined hamartoma of the retina and retinal pigment epithelium (CHRRPE) and to explore potential associations between these developmental ocular anomalies.

Methods

This retrospective, descriptive case series included 9 eyes of 8 patients aged 0-7 years with shared clinical features of PFV and CHRRPE. Diagnoses were established through clinical examination and intraoperative findings.

Results

All eyes exhibited elevated pigmented retinal thickening, increased vascular tortuosity, and preretinal fibrotic/gliotic changes or epiretinal membranes. Macular involvement was observed in 56% of cases; peripapillary involvement, in 44%. Four eyes showed hyaloid stalklike fibrotic remnants extending from the lesion to the posterior lens surface, suggestive of PFV component; the other 5 harbored isolated CHRRPE. One patient presented with PFV in one eye and CHRPPE in the other.

Conclusions

This study reveals significant clinical overlap between PFV and CHRRPE, with some cases displaying features typically associated with the other condition. The presence of both diagnoses in the same patient further suggests a potential association between these entities. Further research, including molecular studies, is needed to explore this potential connection and deepen our understanding of ocular development.

目的：研究具有胎儿血管持续性畸形（PFV）和视网膜及视网膜色素上皮联合火腿肠瘤（CHRPE）重叠特征的病例，并探讨这些眼部发育异常之间的潜在关联：该回顾性、描述性病例系列包括 8 名 0-7 岁患者的 9 只眼睛，这些患者具有 PFV 和 CHRRPE 的共同临床特征。通过临床检查和术中发现确定诊断：结果：所有眼球均表现为色素性视网膜增厚、血管迂曲增加、视网膜前纤维化/胶质细胞病变或视网膜外膜。56%的病例出现黄斑受累，44%的病例出现毛细血管周围受累。有四只眼睛显示从病变处延伸到晶状体后表面的类玻璃体柄状纤维化残余物，提示存在 PFV 成分；另外五只眼睛则存在孤立的 CHRRPE。一名患者的一只眼为 PFV，另一只眼为 CHRPPE：本研究揭示了 PFV 和 CHRRPE 之间存在明显的临床重叠，一些病例显示出与另一种疾病相关的典型特征。在同一患者身上同时出现这两种诊断，进一步表明这两种疾病之间存在潜在的关联。我们需要进一步的研究，包括分子研究，来探索这种潜在的联系，加深我们对眼部发育的理解。

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引用次数: 0

Performance of orbital rapid magnetic resonance imaging (rMRI) as a primary tool for evaluation of suspected pediatric orbital cellulitis 将眼眶快速磁共振成像（rMRI）作为评估疑似小儿眼眶蜂窝织炎的主要工具。

IF 1.2 4区医学 Q3 OPHTHALMOLOGY

Journal of Aapos

Pub Date : 2024-10-01 DOI: 10.1016/j.jaapos.2024.103998

Anas Yasin MD , Steve Mathew , Joseph Maes , Terri Love MD , Angela Beavers MD , Sandra Allbery MD , Andria M. Powers MD , Paul Rychwalski MD , Samiksha Fouzdar Jain MD

In 2021, rapid magnetic resonance imaging (rMRI) became a primary imaging tool for suspected pediatric orbital cellulitis at our institution. We retrospectively reviewed the medical records of patients who underwent rMRI to evaluate the effectiveness of the protocol. A total of 31 patients were included (median age, 5.07 years). Of the 30 diagnostic scans, 11 (37%) showed preseptal cellulitis, and 19 (63%) showed orbital cellulitis. In 5 cases, orbital contrast-enhanced computed tomography (CT) was additionally ordered; rMRI and CT scan findings were similar in all 5 cases. Overall, we observed 93% (28/30) concordance of rMRI with the final clinical diagnosis.

2021 年，快速磁共振成像（rMRI）成为我院疑似小儿眼眶蜂窝织炎的主要成像工具。我们回顾性地查看了接受快速磁共振成像的患者的病历，以评估该方案的有效性。共纳入 31 名患者（中位年龄为 5.07 岁）。在 30 次诊断性扫描中，11 例（37%）显示为眼睑前蜂窝织炎，19 例（63%）显示为眼眶蜂窝织炎。在 5 例病例中，还需要进行眼眶对比增强计算机断层扫描 (CT)；在所有 5 例病例中，rMRI 和 CT 扫描结果相似。总体而言，我们观察到 rMRI 与最终临床诊断的一致性为 93%（28/30）。

引用次数: 0

Unilateral pigmented posterior lenticonus with retinochoroidal coloboma: a case report 单侧色素后皮孔伴视网膜脉络膜巨瘤：病例报告。

IF 1.2 4区医学 Q3 OPHTHALMOLOGY

Journal of Aapos

Pub Date : 2024-10-01 DOI: 10.1016/j.jaapos.2024.103995

Hennaav Kaur Dhillon MS, Abinaya Valliappan MS, FICO, Sumita Agarkar MS, DNB

Posterior lenticonus is a rare congenital anomaly of the crystalline lens characterized by the conical herniation of the posterior lenticular surface with or without cortex herniation into the anterior vitreous. It is usually unilateral and axial; bilateral cases are usually familial and have syndromic associations. The irregular lenticular surface produces high myopia and irregular astigmatism producing optical distortion and hence deprivation amblyopia. We report a case of a 13-year-old girl with a unilateral pigmented posterior lenticonus associated with a retinochoridal coloboma with deprivation amblyopia.

后晶状体疝是一种罕见的先天性晶状体异常，其特点是后晶状体表面呈圆锥形疝出，伴有或不伴有皮质疝入玻璃体前部。这种病通常是单侧和轴性的，双侧病例通常是家族性的，并与综合征有关。不规则的光栅表面会产生高度近视和不规则散光，造成光学畸变，从而导致剥夺性弱视。我们报告了一例 13 岁女孩的病例，她患有单侧色素性后皮孔伴视网膜脉络膜巨瘤，并伴有剥夺性弱视。

引用次数: 0

Validation of the eye screening tool GoCheck Kids for the detection of amblyopia risk factors in toddlers in Flanders 验证 GoCheck Kids 眼科筛查工具，以发现佛兰德幼儿弱视的风险因素。

IF 1.2 4区医学 Q3 OPHTHALMOLOGY

Journal of Aapos

Pub Date : 2024-10-01 DOI: 10.1016/j.jaapos.2024.104008

Hanne Otto MSc , Maaike Deschoemaeker MD , Bart Van Overmeire PhD, MD , Ingele Casteels PhD, MD , Catherine Cassiman PhD, MD

Purpose

To assess the validity of the GoCheck Kids photoscreening application (Gobiquity Mobile Health, Scottdale, AZ) on iPhone, which was used (2018-2022) as standard of care by Child and Family (Kind en Gezin) to detect amblyopia risk factors in children 12-30 months of age.

Methods

Between August 2021 and May 2022, 453 children 11-16 months of age underwent a confirmatory ophthalmic examination within 2 months of GoCheck Kids photoscreening at Child and Family, Flanders, Belgium. Additionally, manual review was performed by specialists of GoCheck Kids. Diagnostic metrics were assessed using the 2013 criteria of the American Association for Pediatric Ophthalmology and Strabismus as reference.

Results

Specificity was similar for automatic screening with or without manual review: 90.0% (95% CI, 87.6%-92.3%) and 90.3% (95% CI, 88.0%-92.7%), respectively. Sensitivity was estimated at 52.0% (95% CI, 35.6%-68.4%) for automatic grading and 56.0% (95% CI, 39.7%-72.3%) after manual review. Positive predictive values for automatic screening and manual review were, respectively, 23.2% (95% CI, 13.9-32.5) and 25.5% (95% CI, 15.8-35.1). Negative predictive values for automatic screening and manual review were, respectively, 97.0% (95% CI, 95.6-98.4) and 97.2 (95% CI, 95.8-98.6).

Conclusions

In our study cohort of children around 12 months of age, the GoCheck Kids application had a specificity of 90% for the targeted amblyopia risk factors, with sensitivity just over 50%.

目的：评估iPhone上的GoCheck Kids照片筛查应用程序（Gobiquity Mobile Health, Scottdale, AZ）的有效性，该应用程序被儿童与家庭（Kind en Gezin）作为标准护理方法（2018-2022年），用于检测12-30个月大儿童的弱视风险因素：2021年8月至2022年5月期间，453名11-16个月大的儿童在比利时佛兰德斯儿童与家庭组织进行GoCheck Kids照片筛查后2个月内接受了眼科确诊检查。此外，GoCheck Kids 的专家还进行了人工复查。诊断指标以美国儿科眼科和斜视协会 2013 年标准为参考进行评估：有无人工审核的自动筛查的特异性相似：结果：有无人工复查的自动筛查的特异性相似：分别为 90.0%（95% CI，87.6%-92.3%）和 90.3%（95% CI，88.0%-92.7%）。自动分级的灵敏度估计为 52.0%（95% CI，35.6%-68.4%），人工复查后的灵敏度估计为 56.0%（95% CI，39.7%-72.3%）。自动筛查和人工复查的阳性预测值分别为 23.2%（95% CI，13.9-32.5）和 25.5%（95% CI，15.8-35.1）。自动筛查和人工复查的阴性预测值分别为 97.0% (95% CI, 95.6-98.4) 和 97.2 (95% CI, 95.8-98.6)：我们的研究对象是 12 个月左右的儿童，GoCheck Kids 应用程序对目标弱视风险因素的特异性为 90%，灵敏度略高于 50%。

{"title":"Validation of the eye screening tool GoCheck Kids for the detection of amblyopia risk factors in toddlers in Flanders","authors":"Hanne Otto MSc , Maaike Deschoemaeker MD , Bart Van Overmeire PhD, MD , Ingele Casteels PhD, MD , Catherine Cassiman PhD, MD","doi":"10.1016/j.jaapos.2024.104008","DOIUrl":"10.1016/j.jaapos.2024.104008","url":null,"abstract":"<div><h3>Purpose</h3><div>To assess the validity of the GoCheck Kids photoscreening application (Gobiquity Mobile Health, Scottdale, AZ) on iPhone, which was used (2018-2022) as standard of care by Child and Family (Kind en Gezin) to detect amblyopia risk factors in children 12-30 months of age.</div></div><div><h3>Methods</h3><div>Between August 2021 and May 2022, 453 children 11-16 months of age underwent a confirmatory ophthalmic examination within 2 months of GoCheck Kids photoscreening at Child and Family, Flanders, Belgium. Additionally, manual review was performed by specialists of GoCheck Kids. Diagnostic metrics were assessed using the 2013 criteria of the American Association for Pediatric Ophthalmology and Strabismus as reference.</div></div><div><h3>Results</h3><div>Specificity was similar for automatic screening with or without manual review: 90.0% (95% CI, 87.6%-92.3%) and 90.3% (95% CI, 88.0%-92.7%), respectively. Sensitivity was estimated at 52.0% (95% CI, 35.6%-68.4%) for automatic grading and 56.0% (95% CI, 39.7%-72.3%) after manual review. Positive predictive values for automatic screening and manual review were, respectively, 23.2% (95% CI, 13.9-32.5) and 25.5% (95% CI, 15.8-35.1). Negative predictive values for automatic screening and manual review were, respectively, 97.0% (95% CI, 95.6-98.4) and 97.2 (95% CI, 95.8-98.6).</div></div><div><h3>Conclusions</h3><div>In our study cohort of children around 12 months of age, the GoCheck Kids application had a specificity of 90% for the targeted amblyopia risk factors, with sensitivity just over 50%.</div></div>","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":"28 5","pages":"Article 104008"},"PeriodicalIF":1.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142299951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Visual and surgical outcomes of childhood glaucoma following cataract surgery 白内障手术后儿童青光眼的视觉和手术效果。

IF 1.2 4区医学 Q3 OPHTHALMOLOGY

Journal of Aapos

Pub Date : 2024-10-01 DOI: 10.1016/j.jaapos.2024.103993

Adam Jacobson MD , Brenda L. Bohnsack MD, PhD

Purpose

To evaluate frequency of surgery and post-treatment outcomes in glaucoma following cataract surgery (GFCS).

Methods

The medical records of patients with GFCS were reviewed retrospectively. Lensectomy and glaucoma surgery details and final examination findings were collected. Inclusion criteria included history of lensectomy at <1 year of age, diagnosis of glaucoma, and at least 1 year of follow-up.

Results

Of 169 eyes of 127 GFCS patients (66 male, 58 bilateral cases), 88 eyes (52%) of 73 (57%) patients underwent glaucoma surgery (median, 3.5 years of age at first glaucoma surgery; median of two glaucoma surgeries). At final follow-up (mean, 13.6 ± 7.0 years), eyes requiring glaucoma surgery had worse visual acuity (P = 0.01) and greater cup:disk ratio (P < 0.01). GFCS patients with history of bilateral congenital cataracts had better visual acuity in affected eyes than those with history of unilateral congenital cataract (P < 0.01). Angle surgery (n = 56), Baerveldt devices (n = 38), Ahmed valves (n = 19), and cycloablation (n = 21) showed 1-year survival rates between 64% and 75%. Baerveldt implants showed the highest 5- and 10-year survival rates, at 65% and 43%, respectively.

Conclusions

More than 50% of eyes with GFCS in our study cohort required at least one glaucoma surgery. Glaucoma surgery and history of unilateral cataract were associated with worse visual acuity outcomes.

目的：评估白内障手术后青光眼（GFCS）的手术频率和治疗后效果：方法：回顾性审查白内障手术后青光眼患者的病历。方法：对 GFCS 患者的病历进行回顾性审查，收集晶体切除术和青光眼手术的详细信息以及最终检查结果。纳入标准包括有晶状体切除术史：在 127 名 GFCS 患者（66 名男性，58 名双侧病例）的 169 只眼睛中，73 名患者（57%）的 88 只眼睛（52%）接受了青光眼手术（首次接受青光眼手术的年龄中位数为 3.5 岁；两次青光眼手术的中位数）。最后随访时（平均 13.6 ± 7.0 年），需要进行青光眼手术的眼睛视力较差（P = 0.01），杯盘比较大（P < 0.01）。与单侧先天性白内障患者相比，有双侧先天性白内障病史的 GFCS 患者的患眼视力更好（P < 0.01）。开眼角手术（56 例）、Baerveldt 装置（38 例）、Ahmed 瓣膜（19 例）和环形消融术（21 例）的 1 年存活率介于 64% 和 75% 之间。Baerveldt植入体的5年和10年存活率最高，分别为65%和43%：结论：在我们的研究队列中，50% 以上的 GFCS 患者至少需要进行一次青光眼手术。青光眼手术和单侧白内障病史与较差的视力结果有关。

{"title":"Visual and surgical outcomes of childhood glaucoma following cataract surgery","authors":"Adam Jacobson MD , Brenda L. Bohnsack MD, PhD","doi":"10.1016/j.jaapos.2024.103993","DOIUrl":"10.1016/j.jaapos.2024.103993","url":null,"abstract":"<div><h3>Purpose</h3><div>To evaluate frequency of surgery and post-treatment outcomes in glaucoma following cataract surgery (GFCS).</div></div><div><h3>Methods</h3><div>The medical records of patients with GFCS were reviewed retrospectively. Lensectomy and glaucoma surgery details and final examination findings were collected. Inclusion criteria included history of lensectomy at <1 year of age, diagnosis of glaucoma, and at least 1 year of follow-up.</div></div><div><h3>Results</h3><div>Of 169 eyes of 127 GFCS patients (66 male, 58 bilateral cases), 88 eyes (52%) of 73 (57%) patients underwent glaucoma surgery (median, 3.5 years of age at first glaucoma surgery; median of two glaucoma surgeries). At final follow-up (mean, 13.6 ± 7.0 years), eyes requiring glaucoma surgery had worse visual acuity (<em>P</em> = 0.01) and greater cup:disk ratio (<em>P</em> < 0.01). GFCS patients with history of bilateral congenital cataracts had better visual acuity in affected eyes than those with history of unilateral congenital cataract (<em>P</em> < 0.01). Angle surgery (n = 56), Baerveldt devices (n = 38), Ahmed valves (n = 19), and cycloablation (n = 21) showed 1-year survival rates between 64% and 75%. Baerveldt implants showed the highest 5- and 10-year survival rates, at 65% and 43%, respectively.</div></div><div><h3>Conclusions</h3><div>More than 50% of eyes with GFCS in our study cohort required at least one glaucoma surgery. Glaucoma surgery and history of unilateral cataract were associated with worse visual acuity outcomes.</div></div>","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":"28 5","pages":"Article 103993"},"PeriodicalIF":1.2,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142299952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Paradoxical keratitis and dermatitis following adalimumab treatment 阿达木单抗治疗后出现的矛盾性角膜炎和皮炎。

IF 1.2 4区医学 Q3 OPHTHALMOLOGY

Journal of Aapos

Pub Date : 2024-10-01 DOI: 10.1016/j.jaapos.2024.103970

Noor Ghali MS , Arif O. Khan MD

Anti-tumor necrosis factor monoclonal antibodies are an important tool in the management of rheumatologic disease. However, paradoxical inflammation can be precipitated by their use. This case report describes the development of keratitis and dermatitis following adalimumab treatment for chronic recurrent multifocal osteomyelitis in a 6-year-old girl. The keratitis and dermatitis subsided once topical steroids were started and the adalimumab was held.

抗肿瘤坏死因子（TNF）单克隆抗体是治疗风湿病的重要工具。然而，使用这种抗体可能会诱发矛盾性炎症。本病例报告描述了一名6岁女孩在接受阿达木单抗治疗慢性复发性多灶性骨髓炎后出现角膜炎和皮炎的情况。在开始使用外用类固醇并停用阿达木单抗后，角膜炎和皮炎均已消退。

引用次数: 0

Risk factors for suprachoroidal hemorrhage associated with glaucoma surgery in children: a case–control study 与儿童青光眼手术相关的脉络膜上腔出血风险因素：病例对照研究。

IF 1.2 4区医学 Q3 OPHTHALMOLOGY

Journal of Aapos

Pub Date : 2024-10-01 DOI: 10.1016/j.jaapos.2024.103973

Rakan Algorinees MD , Abdulrahman Alhomoud MD , Ashwaq Al-Abeeri MD , Abdulrahman Al-Gaeed BSc , Priscilla Gikandi MPH , Rizwan Malik MD, PhD

Purpose

To assess the risk factors for suprachoroidal hemorrhage (SCH) following glaucoma surgery in pediatric patients at a tertiary eye center.

Methods

The medical records of 326 patients (326 eyes) who underwent glaucoma surgery between January 2014, and September 2017 were reviewed retrospectively. Seventeen cases with SCH were compared with 309 controls who underwent uneventful glaucoma surgery during the same period. We documented age, sex, baseline intraocular pressure, glaucoma diagnosis, previous surgery, preoperative axial length, pachymetry, lens status and type of glaucoma surgery performed (whether combined with cataract or other glaucoma procedure or being standalone).

Results

Of the 17 cases of SCH, only a single case occurred intraoperatively; the remainder occurred in the early postoperative period. The most frequent diagnosis was primary congenital glaucoma (PCG), accounting for 10 patients (59%) in cases and 247 (80%) in controls, followed by glaucoma associated with nonacquired ocular anomalies, which accounted for 3 cases (18%) and 22 controls (7%). Aphakia and combined surgeries (in the univariate analysis) were found to be possible risk factors for the development of SCH, with none achieving significance in the multivariable analysis.

Conclusions

In our study cohort, combined surgeries as well aphakia were possible risk factors for SCH.

目的：评估一家三级眼科中心的儿科患者青光眼手术后发生脉络膜上腔出血（SCH）的风险因素：方法：回顾性审查2014年1月至2017年9月期间接受青光眼手术的326名患者（326只眼）的病历。17例SCH患者与同期接受青光眼手术的309例对照组患者进行了比较。我们记录了患者的年龄、性别、基线眼压、青光眼诊断、既往手术情况、术前轴位长度、眼球厚度、晶状体状态和青光眼手术类型（是否与白内障或其他青光眼手术合并进行或单独进行）：在17例SCH病例中，只有一例发生在术中，其余均发生在术后早期。最常见的诊断是原发性先天性青光眼（PCG），病例中有 10 例（59%），对照组中有 247 例（80%），其次是与非后天性眼部异常相关的青光眼，病例中有 3 例（18%），对照组中有 22 例（7%）。在单变量分析中发现，无晶体眼和联合手术可能是SCH发病的风险因素，但在多变量分析中均未发现显著性：在我们的研究队列中，合并手术和无晶体眼都可能是导致SCH的危险因素。

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引用次数: 0

Giant molluscum contagiosum with preseptal cellulitis 巨型软疣伴有隔前蜂窝织炎。

IF 1.2 4区医学 Q3 OPHTHALMOLOGY

Journal of Aapos

Pub Date : 2024-10-01 DOI: 10.1016/j.jaapos.2024.103989

Amitouj S. Sidhu BMed, MD , Josefina Herrera MD , Shereen Aiyub MD, MMed , Nicole S. Graf FRCPA , Trent Sandercoe PhD, FRANZCO , Krishna Tumuluri FRANZCO

Molluscum contagiosum (MC) is a benign cutaneous viral infection commonly affecting children, sexually active adults, immunocompromised individuals, and patients on immunosuppressive therapy. Giant periorbital MC lesions with preseptal cellulitis are rare. We present 2 such pediatric cases. Case 1 was a 9-month-old boy with an enlarging left upper eyelid mass and preseptal cellulitis. MC was confirmed on histopathology, and surgical excision was curative. Case 2 was an 18-month-old girl with a right lower eyelid ulcerating mass and preseptal cellulitis. She was managed with antibiotics and surgical excision.

传染性软疣（MC）是一种良性皮肤病毒感染，常见于儿童、性活跃的成年人、免疫力低下者和接受免疫抑制治疗的患者。眶周巨型 MC 病变伴有眶隔前蜂窝织炎的情况非常罕见。我们介绍 2 例此类儿科病例。病例 1 是一名 9 个月大的男孩，左上眼睑肿块增大，并伴有眶隔前蜂窝织炎。组织病理学证实为 MC，手术切除后治愈。病例 2 是一名 18 个月大的女孩，患有右下眼睑溃疡性肿块和眼睑前蜂窝组织炎。她接受了抗生素治疗和手术切除。

引用次数: 0

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