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Congenital epiblepharon in Chinese school-age children: a cross-sectional study 中国学龄儿童先天性会厌炎:一项横断面研究
IF 1.2 4区 医学 Q3 OPHTHALMOLOGY Pub Date : 2024-08-01 DOI: 10.1016/j.jaapos.2024.103938

Purpose

To investigate the prevalence and body mass index (BMI) associations of congenital lower epiblepharon in children in China and the difference in the refractive errors between children with and without epiblepharon.

Methods

Children 6-12 years of age in Beichen District of Tianjin were screened for congenital epiblepharon from September to October 2017. All children underwent slit-lamp examination, strabismus screening, visual acuity examination and refraction. Weight and height were also recorded. The prevalence of lower epiblepharon in school-age children was evaluated, and its association with age, sex, BMI, and refractive error was analyzed.

Results

A total of 28,225 children were examined; 564 had epiblepharon. The prevalence of epiblepharon was found to be, for 6-year-olds, 2.50%; for 7-year-olds, 2.13%; for 8-year-olds, 2.10%; for 9-year-olds, 1.97%; for 10-year-olds, 1.85%; for 11-year-olds, 1.67%; and for 12-year-olds, 1.19% (P < 0.05). The prevalence of overweight and obesity in children with epiblepharon was found to be 16.7% and 47.2%, respectively. The prevalence and degree of astigmatism was higher than in nonepiblepharon children. We found a possible association between severity of astigmatism and severity of epiblepharon.

Conclusions

In our study, the prevalence of epiblepharon decreased with advancing age, and the majority of children with epiblepharon were found to be overweight or obese. Epiblepharon was associated with astigmatism.

目的 探讨中国儿童先天性下睑外翻的患病率和体重指数(BMI)相关性,以及有外翻儿童和无外翻儿童屈光不正的差异。方法 于2017年9月至10月对天津市北辰区6-12岁儿童进行先天性下睑外翻筛查。所有儿童均接受了裂隙灯检查、斜视筛查、视力检查和屈光检查。同时还记录了体重和身高。评估了学龄儿童下眼睑外翻的患病率,并分析了其与年龄、性别、体重指数和屈光不正的关系。结果发现,6 岁儿童的睑外翻发生率为 2.50%;7 岁儿童为 2.13%;8 岁儿童为 2.10%;9 岁儿童为 1.97%;10 岁儿童为 1.85%;11 岁儿童为 1.67%;12 岁儿童为 1.19%(P < 0.05)。在患有眼睑外翻的儿童中,超重和肥胖的发生率分别为 16.7% 和 47.2%。散光的发生率和散光的程度均高于非睑外翻患儿。结论 在我们的研究中,随着年龄的增长,眼睑外翻的患病率有所下降,大多数眼睑外翻的儿童都超重或肥胖。眼睑外翻与散光有关。
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引用次数: 0
Prolonged hypotony maculopathy following uneventful strabismus surgery 顺利进行斜视手术后出现的长期低眼压黄斑病变。
IF 1.2 4区 医学 Q3 OPHTHALMOLOGY Pub Date : 2024-08-01 DOI: 10.1016/j.jaapos.2024.103939

Hypotony is a rare postoperative complication of strabismus surgery. Resolution has been reported to occur within 1 month of surgery. Here, we describe the case of a 14-year-old boy with prolonged hypotony maculopathy following uneventful bilateral medial rectus recession. The hypotony resolved without long-term sequela after 7 months of treatment with topical steroids and atropine. Ultrasound biomicroscopy revealed a ciliary body effusion, which we hypothesize was the cause of decreased aqueous humor production and hypotony.

眼球下垂是斜视手术后一种罕见的并发症。据报道,术后 1 个月内即可缓解。这里,我们描述了一个 14 岁男孩的病例,他在顺利进行双侧内直肌后退术后出现了长时间的低眼压斑。在使用局部类固醇和阿托品治疗 7 个月后,眼睑下垂症状缓解,未出现长期后遗症。超声生物显微镜检查发现睫状体积液,我们推测这是导致房水分泌减少和眼压过低的原因。
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引用次数: 0
Bilateral nonarteritic ischemic optic neuropathy and retinal ischemia in a pediatric dialysis patient 一名儿童透析患者的双侧非动脉缺血性视神经病变和视网膜缺血。
IF 1.2 4区 医学 Q3 OPHTHALMOLOGY Pub Date : 2024-08-01 DOI: 10.1016/j.jaapos.2024.103948

A nearly 3-year-old boy on nightly dialysis presented emergently with sudden loss of vision. On examination, his visual acuity was light perception in the right eye and no light perception in the left eye. There was bilateral optic disk edema, diffuse pallor of posterior poles, and a cherry red spot in the left fundus. The patient was subsequently found to be hemodynamically unstable and admitted to the pediatric intensive care unit with presumed septic shock. Optical coherence tomography revealed paracentral acute middle maculopathy lesions in the right eye and diffusely thick retina in the left eye. Magnetic resonance imaging and magnetic resonance angiography of the brain and vessels did not reveal any acute findings. The patient’s presentation was most consistent with bilateral nonarteritic ischemic optic neuropathy and unilateral central retinal artery occlusion. On repeat evaluation 9 months later, vision was largely unchanged.

一名正在接受夜间透析的近 3 岁男孩因视力突然下降而急诊就诊。经检查,他的右眼视力为光感,左眼无光感。双侧视盘水肿,后极弥漫性苍白,左眼底有樱桃红色斑点。随后发现患者血流动力学不稳定,被送入儿科重症监护室,推测为脓毒性休克。光学相干断层扫描显示,右眼出现旁中心急性中间黄斑病变,左眼视网膜弥漫性增厚。脑部和血管的磁共振成像和磁共振血管造影未发现任何急性病变。患者的表现最符合双侧非动脉缺血性视神经病变和单侧视网膜中央动脉闭塞。9 个月后再次评估时,视力基本没有变化。
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引用次数: 0
Leukemic infiltration of the ciliary body in a child with T-cell acute lymphoblastic leukemia 一名 T 细胞急性淋巴细胞白血病患儿的睫状体白血病浸润。
IF 1.2 4区 医学 Q3 OPHTHALMOLOGY Pub Date : 2024-08-01 DOI: 10.1016/j.jaapos.2024.103937

A 14-year-old boy presented after 2 months of vision loss, redness, and pain in the right eye, initially treated as anterior uveitis with topical corticosteroids. He had a 1-year history of T-cell acute lymphoblastic leukemia, which had been in remission for 6 months. On examination, visual acuity in the right eye was light perception, with 4+ anterior chamber cells, pupillary membrane, and an intumescent cataract. Ultrasound biomicroscopy (UBM) revealed a ciliary body mass and capsular bag rupture. After consultation with his oncologist, he received 10 radiotherapy sessions. At 1 month, UBM showed resolution of the mass. After 1 year of remission, the patient underwent pars plana vitrectomy, pupillary membranectomy, and placement of a scleral-fixated intraocular lens. Thirty months after surgery, visual acuity was 20/25. Leukemic infiltration of the ciliary body is a rare manifestation of the disease that is often misdiagnosed as uveitis.

一名 14 岁男孩因右眼视力下降、发红和疼痛 2 个月后就诊,起初被当作前葡萄膜炎使用局部皮质类固醇治疗。他曾患 T 细胞急性淋巴细胞白血病 1 年,已缓解 6 个月。经检查,右眼视力为光感,前房细胞4+,瞳孔膜,白内障。超声生物显微镜(UBM)显示睫状体肿块和囊袋破裂。在咨询肿瘤专家后,他接受了 10 次放疗。1 个月后,超声生物显微镜显示肿块消退。缓解一年后,患者接受了玻璃体旁切除术、瞳孔膜切除术和巩膜固定人工晶体植入术。术后 30 个月,视力为 20/25。睫状体白血病浸润是一种罕见的疾病表现,常被误诊为葡萄膜炎。
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引用次数: 0
Small tuck for superior oblique palsy 上斜肌麻痹的小收腹术
IF 1.2 4区 医学 Q3 OPHTHALMOLOGY Pub Date : 2024-08-01 DOI: 10.1016/j.jaapos.2024.103952

Purpose

To investigate the surgical outcomes of small superior oblique (SO) tuck—denoting minimal tendon laxity—in patients with unilateral SO palsy.

Methods

The medical records of consecutive patients treated with ≤6 mm SO tuck from 2000 to 2018 at Kellogg Eye Center, University of Michigan, were reviewed retrospectively. Tendon tucks were performed to a fairly uniform tension in an amount that just eliminated slack in the tendon. Pre- and postoperative motility measurements were compared. Patients were excluded if they had a history of prior strabismus surgery or concurrent vertical rectus or inferior oblique surgery.

Results

A total of 27 cases (14 males) met inclusion criteria. The median age at surgery was 47 years (range 3–74 years). The mean SO tuck (total, both arms of tuck) was 4.9 mm (range, 2–6 mm). After surgery, median hypertropia decreased from 9Δ to 1Δ in primary position and from 20Δ to 4Δ in the SO field of action (contralateral downgaze). Lateral incomitance (difference in hypertropia between contralateral and ipsilateral gaze) decreased from 10Δ to 2Δ (P < 0.001 in each case). Six patients had diplopia in upgaze postoperatively that was not symptomatic enough to require reoperation. Six patients had residual hypertropia requiring additional surgery.

Conclusions

Small SO tuck provided disproportionate correction of hypertropia in the SO field of action and nearly eliminated lateral incomitance without producing unacceptable iatrogenic Brown syndrome. Even in the absence of tendon laxity, SO tuck was a good surgical option for SO palsy in our cohort where there was marked lateral incomitance and the greatest deviation was in the SO field of action.

目的:研究单侧上斜肌麻痹患者接受小范围上斜肌收肌术(即肌腱松弛程度最小的收肌术)的手术效果:方法:回顾性审查密歇根大学凯洛格眼科中心 2000 年至 2018 年期间接受≤6 毫米 SO 收紧术治疗的连续患者的病历。肌腱收紧术的张力相当均匀,刚好消除了肌腱的松弛。比较了术前和术后的活动度测量结果。如果患者之前有斜视手术史或同时接受过垂直直肌或下斜肌手术,则排除在外:共有 27 例患者(14 名男性)符合纳入标准。手术年龄中位数为 47 岁(3-74 岁)。平均SO皱褶(总皱褶,两臂皱褶)为4.9毫米(范围为2-6毫米)。手术后,原位的中位肥厚从9Δ减小到1Δ,SO作用野(对侧下视)从20Δ减小到4Δ。侧方不等距(对侧和同侧注视时的高视度差)从 10Δ 减小到 2Δ(每个病例的 P < 0.001)。六名患者术后出现上视复视,但症状不严重,无需再次手术。六名患者的眼球后凸需要再次手术:结论:小的SO锥切术可以不成比例地矫正SO作用野的肥厚,几乎消除了侧方不对称,但不会产生不可接受的先天性布朗综合征。在我们的病例中,即使没有肌腱松弛,SO收紧术也是治疗SO麻痹的一个很好的手术选择,因为在我们的病例中,存在明显的外侧不对称,而且最大的偏差位于SO作用野。
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引用次数: 0
Malignant rhabdoid tumor of the orbit in an infant 一名婴儿的眼眶恶性横纹肌瘤。
IF 1.2 4区 医学 Q3 OPHTHALMOLOGY Pub Date : 2024-08-01 DOI: 10.1016/j.jaapos.2024.103935

We present the case of an infant with rapidly progressing orbital tumor that had initial radiological and clinical features of both rhabdomyosarcoma and capillary hemangioma. The patient was eventually diagnosed with malignant rhabdoid tumor of the orbit. We discuss the salient histological and radiological features of our case and review the literature on orbital malignant rhabdoid tumors.

我们介绍了一例进展迅速的婴儿眼眶肿瘤病例,该病例最初具有横纹肌肉瘤和毛细血管瘤的放射学和临床特征。患者最终被诊断为眼眶恶性横纹肌瘤。我们讨论了本病例的组织学和放射学特征,并回顾了有关眼眶恶性横纹肌瘤的文献。
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引用次数: 0
Risk factors for suprachoroidal hemorrhage associated with glaucoma surgery in children: a case-control study. 与儿童青光眼手术相关的脉络膜上腔出血风险因素:病例对照研究。
IF 1.2 4区 医学 Q3 OPHTHALMOLOGY Pub Date : 2024-07-26 DOI: 10.1016/j.jaapos.2024.103973
Rakan Algorinees, Abdulrahman Alhomoud, Ashwaq Al-Abeeri, Abdulrahman Al-Gaeed, Priscilla Gikandi, Rizwan Malik

Purpose: To assess the risk factors for suprachoroidal hemorrhage (SCH) following glaucoma surgery in pediatric patients at a tertiary eye center.

Methods: The medical records of 326 patients (326 eyes) who underwent glaucoma surgery between January 2014, and September 2017 were reviewed retrospectively. Seventeen cases with SCH were compared with 309 controls who underwent uneventful glaucoma surgery during the same period. We documented age, sex, baseline intraocular pressure, glaucoma diagnosis, previous surgery, preoperative axial length, pachymetry, lens status and type of glaucoma surgery performed (whether combined with cataract or other glaucoma procedure or being standalone).

Results: Of the 17 cases of SCH, only a single case occurred intraoperatively; the remainder occurred in the early postoperative period. The most frequent diagnosis was primary congenital glaucoma (PCG), accounting for 10 patients (59%) in cases and 247 (80%) in controls, followed by glaucoma associated with nonacquired ocular anomalies, which accounted for 3 cases (18%) and 22 controls (7%). Aphakia and combined surgeries (in the univariate analysis) were found to be possible risk factors for the development of SCH, with none achieving significance in the multivariable analysis.

Conclusions: In our study cohort, combined surgeries as well aphakia were possible risk factors for SCH.

目的:评估一家三级眼科中心的儿科患者青光眼手术后发生脉络膜上腔出血(SCH)的风险因素:方法:回顾性审查2014年1月至2017年9月期间接受青光眼手术的326名患者(326只眼)的病历。17例SCH患者与同期接受青光眼手术的309例对照组患者进行了比较。我们记录了患者的年龄、性别、基线眼压、青光眼诊断、既往手术情况、术前轴位长度、眼球厚度、晶状体状态和青光眼手术类型(是否与白内障或其他青光眼手术合并进行或单独进行):在17例SCH病例中,只有一例发生在术中,其余均发生在术后早期。最常见的诊断是原发性先天性青光眼(PCG),病例中有 10 例(59%),对照组中有 247 例(80%),其次是与非后天性眼部异常相关的青光眼,病例中有 3 例(18%),对照组中有 22 例(7%)。在单变量分析中发现,无晶体眼和联合手术可能是SCH发病的风险因素,但在多变量分析中均未发现显著性:在我们的研究队列中,合并手术和无晶体眼都可能是导致SCH的危险因素。
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引用次数: 0
Paradoxical keratitis and dermatitis following adalimumab treatment. 阿达木单抗治疗后出现的矛盾性角膜炎和皮炎。
IF 1.2 4区 医学 Q3 OPHTHALMOLOGY Pub Date : 2024-07-14 DOI: 10.1016/j.jaapos.2024.103970
Noor Ghali, Arif O Khan

Anti-tumor necrosis factor monoclonal antibodies are an important tool in the management of rheumatologic disease. However, paradoxical inflammation can be precipitated by their use. This case report describes the development of keratitis and dermatitis following adalimumab treatment for chronic recurrent multifocal osteomyelitis in a 6-year-old girl. The keratitis and dermatitis subsided once topical steroids were started and the adalimumab was held.

抗肿瘤坏死因子(TNF)单克隆抗体是治疗风湿病的重要工具。然而,使用这种抗体可能会诱发矛盾性炎症。本病例报告描述了一名6岁女孩在接受阿达木单抗治疗慢性复发性多灶性骨髓炎后出现角膜炎和皮炎的情况。在开始使用外用类固醇并停用阿达木单抗后,角膜炎和皮炎均已消退。
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引用次数: 0
The association between race and age of diagnosis of retinoblastoma in United States children 就 "美国儿童视网膜母细胞瘤的种族与诊断年龄之间的关系 "发表评论。
IF 1.6 4区 医学 Q3 Medicine Pub Date : 2024-06-01 DOI: 10.1016/j.jaapos.2024.103932
Francisco Altamirano-Lamarque MD, Efren Gonzalez MD, Isdin Oke MD, MPH
{"title":"The association between race and age of diagnosis of retinoblastoma in United States children","authors":"Francisco Altamirano-Lamarque MD,&nbsp;Efren Gonzalez MD,&nbsp;Isdin Oke MD, MPH","doi":"10.1016/j.jaapos.2024.103932","DOIUrl":"10.1016/j.jaapos.2024.103932","url":null,"abstract":"","PeriodicalId":50261,"journal":{"name":"Journal of Aapos","volume":null,"pages":null},"PeriodicalIF":1.6,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140892868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pilot study comparing a new virtual reality–based visual field test to standard perimetry in children 将基于虚拟现实的新型儿童视野测试与标准视力测试进行比较的试点研究。
IF 1.6 4区 医学 Q3 Medicine Pub Date : 2024-06-01 DOI: 10.1016/j.jaapos.2024.103933
Yeabsira Mesfin BS , Alan Kong MD , Benjamin T. Backus PhD , Michael Deiner PhD , Yvonne Ou MD , Julius T. Oatts MD

Purpose

To assess the feasibility and performance of Vivid Vision Perimetry (VVP), a new virtual reality (VR)–based visual field platform.

Methods

Children 7-18 years of age with visual acuity of 20/80 or better undergoing Humphrey visual field (HVF) testing were recruited to perform VVP, a VR-based test that uses suprathreshold stimuli to test 54 field locations and calculates a fraction seen score. Pearson correlation coefficients were calculated to evaluate correlation between HVF mean sensitivity and VVP mean fraction seen scores. Participants were surveyed regarding their experience.

Results

A total of 37 eyes of 23 participants (average age, 12.9 ± 3.1 years; 48% female) were included. All participants successfully completed VVP testing. Diagnoses included glaucoma (12), glaucoma suspect (7), steroid-induced ocular hypertension (3), and craniopharyngioma (1). Sixteen participants had prior HVF experience, and none had prior VVP experience, although 7 had previously used VR. Of the 23 HVF tests performed, 9 (39%) were unreliable due to fixation losses, false positives, or false negatives. Similarly, 35% of VVP tests were unreliable (as defined by accuracy of blind spot detection). Excluding unreliable HVF tests, the correlation between HVF average mean sensitivity and VVP mean fraction seen score was 0.48 (P = 0.02; 95% CI, 0.09-0.74). When asked about preference for the VVP or HVF examination, all participants favored the VVP, and 70% were “very satisfied” with VVP.

Conclusions

In our cohort of 23 pediatric subjects, VVP proved to be a clinically feasible VR-based visual field testing, which was uniformly preferred over HVF.

目的:评估基于虚拟现实(VR)的全新视野平台Vivid Vision Perimetry(VVP)的可行性和性能:方法:招募视力在 20/80 或更佳的 7-18 岁儿童进行汉弗莱视野(HVF)测试,并进行 VVP 测试。VVP 是一种基于虚拟现实的测试,使用阈上刺激测试 54 个视野位置,并计算出所见分数。通过计算皮尔逊相关系数来评估 HVF 平均灵敏度与 VVP 平均可见分数之间的相关性。对参与者进行了经验调查:共纳入 23 名参与者的 37 只眼睛(平均年龄为 12.9 ± 3.1 岁;48% 为女性)。所有参与者都成功完成了 VVP 测试。诊断包括青光眼(12 例)、疑似青光眼(7 例)、类固醇引起的眼压过高(3 例)和颅咽管瘤(1 例)。16 名参与者之前有过高频荧光检测经验,没有人有过 VVP 经验,但有 7 人曾使用过 VR。在进行的 23 次 HVF 测试中,有 9 次(39%)由于固定损失、假阳性或假阴性而不可靠。同样,35% 的 VVP 测试也不可靠(以准确检测盲点为标准)。排除不可靠的 HVF 测试,HVF 平均灵敏度与 VVP 平均可见分数之间的相关性为 0.48(P = 0.02;95% CI,0.09-0.74)。当被问及对 VVP 或 HVF 检查的偏好时,所有参与者都倾向于 VVP,70% 的人对 VVP 表示 "非常满意":在我们的 23 名儿科受试者中,VVP 被证明是一种临床上可行的基于 VR 的视野测试,与 HVF 相比,所有受试者都更倾向于 VVP。
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引用次数: 0
期刊
Journal of Aapos
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