Pub Date : 2024-07-01DOI: 10.1016/j.omtn.2024.102280
Heshadi Primrose Mandalawatta, Rajendra Kc, Kirsten A. Fairfax, A. Hewitt
{"title":"Emerging trends in virus and virus-like particle gene therapy delivery to the brain","authors":"Heshadi Primrose Mandalawatta, Rajendra Kc, Kirsten A. Fairfax, A. Hewitt","doi":"10.1016/j.omtn.2024.102280","DOIUrl":"https://doi.org/10.1016/j.omtn.2024.102280","url":null,"abstract":"","PeriodicalId":503104,"journal":{"name":"Molecular Therapy - Nucleic Acids","volume":"150 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141841758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.1016/j.omtn.2024.102281
Shuangxiang Xu, Tong-Tong Chen, Jin Yu, Lei Wan, Jianjian Zhang, Jincao Chen, Wei Wei, Xiang Li
{"title":"Insights into the Regulatory Role of Epigenetics in Moyamoya Disease: Current Advances and Future prospectives","authors":"Shuangxiang Xu, Tong-Tong Chen, Jin Yu, Lei Wan, Jianjian Zhang, Jincao Chen, Wei Wei, Xiang Li","doi":"10.1016/j.omtn.2024.102281","DOIUrl":"https://doi.org/10.1016/j.omtn.2024.102281","url":null,"abstract":"","PeriodicalId":503104,"journal":{"name":"Molecular Therapy - Nucleic Acids","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141850415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.1016/j.omtn.2024.102284
Andrew J. Fisher, Peter A Beal
{"title":"Structural Perspectives on Adenosine to Inosine RNA editing by ADARs","authors":"Andrew J. Fisher, Peter A Beal","doi":"10.1016/j.omtn.2024.102284","DOIUrl":"https://doi.org/10.1016/j.omtn.2024.102284","url":null,"abstract":"","PeriodicalId":503104,"journal":{"name":"Molecular Therapy - Nucleic Acids","volume":"204 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141840268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.1016/j.omtn.2024.102283
Christian Grützner, Y. Tan, Patrick Müller, Thais M. Schlee-Guimarães, Marius Jentzsch, Jonathan L. Schmid-Burgk, Marcel Renn, Rayk Behrendt, Gunther Hartmann
{"title":"Synthetic RIG-I agonist-mediated cancer immunotherapy synergizes with MAP-Kinase inhibition against BRAF mutated melanoma","authors":"Christian Grützner, Y. Tan, Patrick Müller, Thais M. Schlee-Guimarães, Marius Jentzsch, Jonathan L. Schmid-Burgk, Marcel Renn, Rayk Behrendt, Gunther Hartmann","doi":"10.1016/j.omtn.2024.102283","DOIUrl":"https://doi.org/10.1016/j.omtn.2024.102283","url":null,"abstract":"","PeriodicalId":503104,"journal":{"name":"Molecular Therapy - Nucleic Acids","volume":"7 14","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141845168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.1016/j.omtn.2024.102278
Mouraya Hussein, Ye Liu, Monique A. Vink, Pascal Kroon, A. Das, B. Berkhout, E. Herrera-Carrillo
{"title":"Evaluation of the effect of RNA secondary structure on Cas13d-mediated target RNA cleavage","authors":"Mouraya Hussein, Ye Liu, Monique A. Vink, Pascal Kroon, A. Das, B. Berkhout, E. Herrera-Carrillo","doi":"10.1016/j.omtn.2024.102278","DOIUrl":"https://doi.org/10.1016/j.omtn.2024.102278","url":null,"abstract":"","PeriodicalId":503104,"journal":{"name":"Molecular Therapy - Nucleic Acids","volume":"17 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141849946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.1016/j.omtn.2024.102279
Samita Kafle, Brian Montoya, Lingjuan Tang, Ying K. Tam, Hiromi Muramatsu, N. Pardi, L. Sigal
{"title":"The roles of CD4+ T-cell help, sex, and dose in the induction of protective CD8+ T-cells against a lethal poxvirus by mRNA-LNP vaccines.","authors":"Samita Kafle, Brian Montoya, Lingjuan Tang, Ying K. Tam, Hiromi Muramatsu, N. Pardi, L. Sigal","doi":"10.1016/j.omtn.2024.102279","DOIUrl":"https://doi.org/10.1016/j.omtn.2024.102279","url":null,"abstract":"","PeriodicalId":503104,"journal":{"name":"Molecular Therapy - Nucleic Acids","volume":"6 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141844911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-01DOI: 10.1016/j.omtn.2024.102233
Andreia Vilaça, C. Jesus, Miguel Lino, Danika Hayman, C. Emanueli, C. Terracciano, Hugo Fernandes, Leon J. de Windt, L. Ferreira
{"title":"Extracellular vesicle transfer of lncRNA H19 splice variants to cardiac cells","authors":"Andreia Vilaça, C. Jesus, Miguel Lino, Danika Hayman, C. Emanueli, C. Terracciano, Hugo Fernandes, Leon J. de Windt, L. Ferreira","doi":"10.1016/j.omtn.2024.102233","DOIUrl":"https://doi.org/10.1016/j.omtn.2024.102233","url":null,"abstract":"","PeriodicalId":503104,"journal":{"name":"Molecular Therapy - Nucleic Acids","volume":"51 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141275220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-01DOI: 10.1016/j.omtn.2024.102247
K. Andrysiak, Paweł E. Ferdek, A. Sanetra, G. Machaj, Luisa Schmidt, I. Kraszewska, K. Sarad, K. Palus-Chramiec, Olga Lis, Marta Targosz-Korecka, Marcus Krüger, Marian H. Lewandowski, Guillem Ylla, J. Stępniewski, Józef Dulak
{"title":"Upregulation of utrophin improves the phenotype of Duchenne muscular dystrophy hiPSC-derived cardiomyocytes","authors":"K. Andrysiak, Paweł E. Ferdek, A. Sanetra, G. Machaj, Luisa Schmidt, I. Kraszewska, K. Sarad, K. Palus-Chramiec, Olga Lis, Marta Targosz-Korecka, Marcus Krüger, Marian H. Lewandowski, Guillem Ylla, J. Stępniewski, Józef Dulak","doi":"10.1016/j.omtn.2024.102247","DOIUrl":"https://doi.org/10.1016/j.omtn.2024.102247","url":null,"abstract":"","PeriodicalId":503104,"journal":{"name":"Molecular Therapy - Nucleic Acids","volume":"18 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141397754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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