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Pathological Study of Rare Case of Duodenal Leiomyosarcoma in a Labrador Dog 拉布拉多犬十二指肠横纹肌肉瘤罕见病例的病理学研究
Pub Date : 2024-03-18 DOI: 10.47191/ijcsrr/v7-i3-33
Dr. Prashant Sonkusale, U.P. Mainde, Chaitanya S, Samiksha Suroshe
The leiomyosarcoma is a tumor of mesenchymal origin of smooth, malignant, slow-growing muscles. The present study reports a case of duodenal leiomyosarcoma in Labrador dog. A 6 year old black female Labrador dog with history off feed, vomition and melena brought for necropsy examination. Gross lesions revealed tennis ball size tumorus mass at the initial portion of duodenum resulting into the obstruction of intestinal lumen. Microscopically, duodenum with tumours mass revealed smooth muscle bundles arranged in all the directions having elongated blunt ended nuclei along with numerous blood vessels and mitotic figure which is indicative of leiomyosarcoma.
子宫肌瘤是一种起源于间质的平滑肌肿瘤,具有恶性和生长缓慢的特点。本研究报告了一例拉布拉多犬十二指肠肌瘤。这是一只 6 岁的黑色雌性拉布拉多犬,曾出现断食、呕吐和腹泻症状,被送去进行尸体解剖检查。大体病变显示,十二指肠起始部有网球大小的肿块,导致肠腔阻塞。显微镜下,带有肿瘤块的十二指肠显示出平滑肌束向各个方向排列,具有细长的钝端细胞核,以及大量血管和有丝分裂图,这表明该犬患的是白肌肉瘤。
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引用次数: 0
Efficacy of Botanical Oils on Adult Mortality, Egg Laying, Hatchability and Adult Emergence of Callosobruchus. Maculatus (F.) (Coleoptera: Chrysomelidae: Bruchidae) 植物油对 Callosobruchus.Maculatus (F.) (Coleoptera: Chrysomelidae: Bruchidae)
Pub Date : 2024-03-18 DOI: 10.47191/ijcsrr/v7-i3-29
Abdullah Ahmady, Mohammad Raees Mukhles, Abdullah Naseri, Abdul Jamil Ahmadi, Fahim Andar
The cowpea weevil Callosobruchus maculatus Fabricius, is the major insect pest that threatens effective legume storage. The laboratory experiment was conducted to assess the efficacy of four different botanical oils (Clove, Eucalyptus, Jojoba and Lemon) against the cowpea weevil, C. maculatus by using residual film technique. All the botanical oils were applied at two different concentration levels (0/50 and 0.75%). The results showed that all used oils significantly increased the mortality and reduced the mean number of eggs laying, hatchability and emergence percentages compared to the untreated control. The treatment of cowpea seeds with oils reduced slightly the germination but swelling percentage was higher in treated seeds than control. The results also indicated variation in the activity of botanical oils regarding the stage of the insect, the plant origin of the oils and concentration level. The present study suggested that botanical oils (Clove, Eucalyptus, Jojoba and Lemon) may be preferred option than conventional pesticides far the protecting stored pulse grains against stored products insect pests’ infestation, especially C. maculatus.
豇豆象鼻虫(Callosobruchus maculatus Fabricius)是威胁豆类有效贮藏的主要害虫。本实验室实验采用残膜技术评估了四种不同植物油(丁香、桉树、荷荷巴油和柠檬)对豇豆象鼻虫的功效。所有植物油均以两种不同的浓度水平(0/50 和 0.75%)施用。结果表明,与未处理的对照组相比,所有使用过的植物油都能显著提高死亡率,降低平均产卵数、孵化率和出苗率。用油处理豇豆种子后,发芽率略有降低,但处理后种子的膨胀率高于对照组。研究结果还表明,植物油的活性因昆虫的阶段、植物油的来源和浓度水平而异。本研究表明,植物油(丁香、桉树、荷荷巴油和柠檬)可能是比传统杀虫剂更有效的保护贮藏谷物免受贮藏产品害虫(尤其是大斑椿害虫)侵扰的选择。
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引用次数: 0
Effects of Fresh Azolla microphylla Supplementation on Pelleted Basal Diet to Local Muscovy Duck Breed Production Performances 在颗粒基础日粮中添加新鲜毛鹃对当地麝香鸭品种生产性能的影响
Pub Date : 2024-03-15 DOI: 10.47191/ijcsrr/v7-i3-27
Firmansyah Budi Pratama, I. Djunaidi, Eko Widodo
The study was aimed to evaluate the effect of feeding fresh Azolla microphylla on pelleted basal feed on the Local muscovy duck breed production performances. The research was done for 2 months August to September 2023, in the Muscovy duck farm, Paguyuban Petani Mandiri Kademangan, (PPMK), Blitar Regency, and feed analysis was done in the Nutrition and Animal Feed Laboratory, Faculty of Animal Science, Muhammadiyah Malang University. The research method used is experiment using a completely randomized design consisting of 3 treatments and 5 replications, each experimental unit used 4 ducks, reared and plotted randomly in the litter cage. The research variables observed were: day old duck weight, final weight, feed intake, FCR and performance index. The results of the study of the effect of supplementation 10% of fresh Azolla microphylla on the best performance index of Muscovy duck (Cairina moschata), can be apply for duck feed.
该研究旨在评估在颗粒基础饲料中添加新鲜微囊绿藻对当地麝香鸭品种生产性能的影响。研究于 2023 年 8 月至 9 月在 Blitar Regency 的 Paguyuban Petani Mandiri Kademangan(PPMK)麝香鸭养殖场进行,为期 2 个月,饲料分析在 Muhammadiyah Malang 大学动物科学学院营养与动物饲料实验室完成。采用的研究方法是完全随机设计实验,包括 3 个处理和 5 次重复,每个实验单元使用 4 只鸭子,随机饲养并放置在产仔笼中。观察的研究变量包括:鸭子的日龄体重、最终体重、采食量、FCR 和性能指标。研究结果表明,补充 10%的新鲜微囊绿藻对鸭子(Cairina moschata)的最佳性能指标有影响,可用于鸭饲料中。
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引用次数: 0
Development and Validation of a Viable and User-Friendly Spectrophotometric Analytical Method for Estimation of Assay of Formoterol and Beclomethasone in Metered Dose Inhaler Formulation 开发和验证可行且便于使用的分光光度分析法,用于评估计量吸入剂配方中福莫特罗和倍氯米松的含量
Pub Date : 2024-03-15 DOI: 10.47191/ijcsrr/v7-i3-28
Vinod Musale, Pranav Shah
The primary aim of this research endeavor is to innovate a viable and user-friendly UV spectroscopic approach for quantifying formoterol and beclomethasone within metered dose inhalers (MDIs). These formulations, amalgamating Beclomethasone Dipropionate (BDP) and Formoterol Fumarate (FF), are extensively employed in managing bronchial asthma and chronic obstructive pulmonary diseases. Although analytical techniques already exist for assessing formoterol and beclomethasone in combination dry powder inhalers, this study concentrates on devising and validating a UV spectrophotometric method for simultaneously quantifying formoterol fumarate and Anhydrous Beclomethasone Dipropionate in Pressurized Metered Dose Inhalers (pMDIs). The estimation is performed at a wavelength of 240 nm for Beclomethasone Dipropionate and 216 nm for Formoterol Fumarate. Both drugs demonstrate satisfactory linearity within the concentration range of 10-30 μg/ml for BDP and 0.3 to 0.9 μg/ml for FF at wavelengths of 240 nm (r^2=0.999) and 216 nm (r^2=0.999), respectively. The Beer-Lambert law is adhered to within the concentration range of 10-30 μg/ml for BDP and 0.3-0.9 μg/ml for FF. The proposed methods are subjected to validation following ICH guidelines to assess accuracy, method precision, specificity, among other parameters. As a result, the proposed method can be effectively employed for the simultaneous determination of Beclomethasone Dipropionate and Formoterol Fumarate in routine analytical applications, offering a rapid and reliable solution for pharmaceutical analysis in the field.
这项研究工作的主要目的是创新一种可行且用户友好的紫外光谱方法,用于量化计量吸入器(MDI)中的福莫特罗和倍氯米松。这些配方混合了二丙酸倍氯米松(BDP)和富马酸福莫特罗(FF),被广泛用于治疗支气管哮喘和慢性阻塞性肺病。虽然已有分析技术可用于评估复方干粉吸入器中的福莫特罗和倍氯米松,但本研究集中于设计和验证一种紫外分光光度法,用于同时量化加压计量吸入器(pMDIs)中的富马酸福莫特罗和二丙酸无水倍氯米松。二丙酸倍氯米松的检测波长为 240 nm,富马酸福莫特罗的检测波长为 216 nm。在 240 nm 波长(r^2=0.999)和 216 nm 波长(r^2=0.999)下,两种药物的线性范围分别为 10-30 μg/ml 和 0.3-0.9 μg/ml。在 BDP 浓度为 10-30 μg/ml 和 FF 浓度为 0.3-0.9 μg/ml 的范围内,均符合比尔-朗伯定律。根据 ICH 指南对所提出的方法进行了验证,以评估准确度、方法精密度和特异性等参数。因此,所提出的方法可有效地用于常规分析中同时测定二丙酸倍氯米松和富马酸福莫特罗,为药物分析领域提供了快速可靠的解决方案。
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引用次数: 0
The Efforts of Arab and Muslim Scientists in Pharmacy, Practically and Theoretically – Treating Poisons as an Example 阿拉伯和穆斯林科学家在药剂学方面的实践和理论努力--以毒药治疗为例
Pub Date : 2024-03-14 DOI: 10.47191/ijcsrr/v7-i3-22
Dr. Mohamed Shafei Moftah Bosheya
Pharmacy is considered a science and a profession in all human civilizations. Toxic substances are considered health problems that many people face and require prevention and treatment. Arabs and Muslims, in general, have shown interest in pharmacy, and specifically in toxins, both practically and theoretically. This is the focus of this research, which aims to introduce the science of pharmacy, highlight the efforts of Arabs and Muslims in it, especially in combating toxins through prevention, treatment, classification, and definition. The research also aims to introduce some of the works they have written in this field and assess their usefulness, using a descriptive-analytical approach and a historical approach to trace the significant contributions of Arabs and Muslims in pharmacy and toxins over time. The research, with reference to specialized sources in each field, concludes with several key findings, including the significant contribution of Islamic civilization to pharmacy and toxins, benefiting many other nations from these efforts.
药剂学在所有人类文明中都被视为一门科学和一种职业。有毒物质被认为是许多人面临的健康问题,需要预防和治疗。阿拉伯人和穆斯林在实践和理论方面都对药学,特别是对毒素表现出浓厚的兴趣。这就是本研究的重点,旨在介绍药剂学,突出阿拉伯人和穆斯林在这方面所做的努力,特别是通过预防、治疗、分类和定义来对抗毒素。研究还旨在介绍他们在这一领域撰写的一些作品,并评估这些作品的实用性,采用描述-分析方法和历史方法,追溯阿拉伯人和穆斯林长期以来在药学和毒素方面做出的重大贡献。研究参考了各领域的专业资料,最后得出了一些重要结论,包括伊斯兰文明对药剂学和毒素学的重大贡献,许多其他国家也从这些努力中受益。
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引用次数: 0
The Effect of Capital Structure on the Ho Chi Minh Stock Exchange (HOSE) Performance of Companies Listed in the Plastics Industry 资本结构对胡志明证券交易所(HOSE)塑料行业上市公司绩效的影响
Pub Date : 2024-03-14 DOI: 10.47191/ijcsrr/v7-i3-25
Nguyen Duc Dat
The relationship between capital structure and company performance was examined in this study. From 2019 to 2023, information was gathered from 29 plastic firms that were listed on the Ho Chi Minh Stock Exchange (HOSE). Each company’s performance was gauged using three variables: ROA, ROE, and EPS. The major components of capital structure are the ratios of total debt to total assets (DA), total debt to equity (DE), short-term debt to total assets (SDTA), and long-term debt to total assets (LDTA). In addition, the model incorporates growth rate (GROWTH) and company size (SIZE) as control variables. Consequently, every performance characteristic of the company is negatively impacted by the majority of the capital structure variables. Notably, this study not only demonstrates the weak association between SDTA and SDTA but also the negative correlation between ROE and capital structure, which was considered minor in many earlier studies. Furthermore, prior research had not consistently shown ROE. Additionally, the study’s findings indicate that size and company performance are positively correlated and have no effect on growth pace.
本研究探讨了资本结构与公司业绩之间的关系。从 2019 年到 2023 年,我们收集了在胡志明证券交易所(HOSE)上市的 29 家塑料公司的信息。每家公司的业绩都通过三个变量来衡量:ROA、ROE 和 EPS。资本结构的主要组成部分是总债务与总资产比率(DA)、总债务与股本比率(DE)、短期债务与总资产比率(SDTA)和长期债务与总资产比率(LDTA)。此外,模型还将增长率(GROWTH)和公司规模(SIZE)作为控制变量。因此,公司的每个绩效特征都会受到大多数资本结构变量的负面影响。值得注意的是,本研究不仅证明了 SDTA 与 SDTA 之间的微弱关联,还证明了 ROE 与资本结构之间的负相关,而这在之前的许多研究中被认为是次要的。此外,之前的研究也没有一致地显示 ROE。此外,研究结果表明,规模和公司业绩呈正相关,对增长速度没有影响。
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引用次数: 0
Enhancing Network Security through Advanced Authentication and Key Management Mechanisms 通过高级认证和密钥管理机制增强网络安全
Pub Date : 2024-03-14 DOI: 10.47191/ijcsrr/v7-i3-26
Annu Annu, Dr. Anil Duddy, Dr. Nidhi
This paper introduces the SEAKS-PKMv2 protocol, a robust security mechanism aimed at addressing vulnerabilities within the PKMv2 framework, particularly focusing on mutual authentication, key management, and encryption in mobile WiMAX networks. By integrating RSA-based and EAP-based authentication methods, SEAKS-PKMv2 establishes a secure environment that mitigates risks such as replay, man-in-the-middle and interleaving attacks. The protocol adopts a distributed authentication and localized key management approach, facilitating efficient and secure network access and data transmission. Through simulation, we evaluate the SEAKS-PKMv2 protocol’s performance in terms of packet delivery ratio, overhead, processing time, and resilience against rogue relay station attacks. The findings demonstrate significant improvements in network security and efficiency, confirming the effectiveness of SEAKS-PKMv2 in enhancing the integrity and confidentiality of communications in distributed network settings.
本文介绍了 SEAKS-PKMv2 协议,它是一种强大的安全机制,旨在解决 PKMv2 框架内的漏洞,尤其侧重于移动 WiMAX 网络中的相互验证、密钥管理和加密。通过整合基于 RSA 和 EAP 的验证方法,SEAKS-PKMv2 建立了一个安全的环境,可降低重放、中间人和交错攻击等风险。该协议采用分布式认证和本地化密钥管理方法,促进了高效、安全的网络访问和数据传输。通过仿真,我们评估了 SEAKS-PKMv2 协议在数据包传送率、开销、处理时间和抵御流氓中继站攻击等方面的性能。研究结果表明,SEAKS-PKMv2 在网络安全和效率方面都有显著提高,证实了它在增强分布式网络环境中通信的完整性和保密性方面的有效性。
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引用次数: 0
Application of MLR Method and Pearson Correlation on Nickel Extraction from Laterite Using Nitric Acid 使用硝酸从红土中提取镍的 MLR 方法和皮尔逊相关性的应用
Pub Date : 2024-03-14 DOI: 10.47191/ijcsrr/v7-i3-24
W. Dahani, Rita Sundari, Rosmalia Nugraheni, S. Subandrio, Ahmad Pangeran
Indonesia is a country rich in laterite mining especially in Celebes island and northern Moluccas. Laterite is a mineral rich with precious nickel. Nitric acid leaching has been used for nickel extraction from laterite under the influence of nitric acid concentration (2.0 M, 4.0 M, and 6.0 M) and leaching temperature (65oC, 70oC, and 75oC) during 60 min. at 300 rpm. The preliminary study aims to apply multiple linear regression (MLR) method to examine the dominant effect between acid concentration and leaching temperature on nickel extraction, and also Pearson correlation to study significant correlation between the variables involved (acid concentration, leaching temperature, and nickel concentration). The method and results is related to acid leaching at varied temperature set up as predictors and nickel concentration as dependent variable in the MLR equation using the enter method. The MLR method showed that acid concentration gave significant effect on nickel concentration, however, the leaching temperature showed no significant effect on nickel extraction at t ≤ 0.05. The Pearson correlation showed acid concentration correlated significantly with nickel concentration. The Kolmogrov-Smirnov (K-S) test showed normality for distribution of nickel concentration. The acid leaching method is potential for nickel extraction from laterite using extensive range of acid concentrations and leaching temperatures to improve nickel extraction.
印度尼西亚是一个红土矿产丰富的国家,尤其是在西里伯斯岛和摩鹿加群岛北部。红土是一种富含贵重镍的矿物。在硝酸浓度(2.0 M、4.0 M 和 6.0 M)和浸出温度(65oC、70oC 和 75oC)的影响下,采用硝酸浸出法从红土中提取镍,浸出时间为 60 分钟,浸出转速为 300 转/分。初步研究旨在应用多元线性回归(MLR)方法来检验酸浓度和浸出温度对镍萃取的主要影响,并应用皮尔逊相关性来研究相关变量(酸浓度、浸出温度和镍浓度)之间的显著相关性。该方法和结果是以不同温度下的酸浸出为预测变量,以镍浓度为因变量,采用回车法计算 MLR 方程。MLR 方法表明,酸浓度对镍浓度有显著影响,但在 t ≤ 0.05 时,浸出温度对镍提取无显著影响。皮尔逊相关性表明,酸浓度与镍浓度有显著相关性。Kolmogrov-Smirnov(K-S)检验表明镍浓度分布呈正态分布。酸浸出法具有从红土中提取镍的潜力,可使用多种酸浓度和浸出温度来提高镍的提取率。
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引用次数: 0
Strategies to Improve the Sales Performance of Car Loan Products in Bank Shinhan Indonesia 印尼新韩银行提高汽车贷款产品销售业绩的策略
Pub Date : 2024-03-14 DOI: 10.47191/ijcsrr/v7-i3-23
Tri Wulan Defridayanti S.Hum, Ana Noveria SE, MBA, PHD
In internal Bank Shinhan, My Car Loan is one of their top consumer products. However, when compared to other car financing competitors, Bank Shinhan was far behind in terms of sales performance. Hyundai Motors Indonesia has four official financial partners to support its car purchasing, namely: Maybank Finance, Mandiri Tunas Finance, Sunindo KB Finance, and Bank Shinhan. The company is the only bank-based financial partner, while the three others were multi-finance companies that specialized in car financing. Moreover, two of them, Mandiri Tunas Finance and Maybank were already well-known players in the car financing industry. Meanwhile, Bank Shinhan is a new player with low brand awareness among the public. In this research, the data collection methods were interviews and questionnaires. As for the research method, for the questionnaire data, the author used the NPS (Net Promoter Score) method and reliability test. As for the interview data, the author used the TA (thematic analysis) method. With this research, the author aimed to get insights to propose new strategies.
在新韩银行内部,"我的汽车贷款 "是其顶级消费产品之一。然而,与其他汽车金融竞争对手相比,新韩银行在销售业绩方面远远落后。印尼现代汽车公司有四个官方金融合作伙伴为其购车提供支持,即Maybank Finance、Mandiri Tunas Finance、Sunindo KB Finance 和新韩银行。该公司是唯一一家以银行为基础的金融合作伙伴,其他三家则是专门从事汽车融资的综合金融公司。此外,其中两家公司,Mandiri Tunas Finance 和 Maybank 已经是汽车融资行业的知名企业。与此同时,新韩银行是一家新公司,在公众中的品牌知名度较低。本研究的数据收集方法是访谈和问卷调查。在研究方法上,对于问卷数据,作者采用了 NPS(净推荐值)法和信度检验法。至于访谈数据,作者使用了主题分析法(TA)。通过这项研究,作者旨在获得洞察力,从而提出新的战略。
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引用次数: 0
Integrated Marketing Communication Strategy to Increase Brand Equity of BPJS Kesehatan 提高 BPJS Kesehatan 品牌资产的整合营销传播战略
Pub Date : 2024-03-13 DOI: 10.47191/ijcsrr/v7-i3-21
Ryan Abdullah Putra, I. Zaim, S. A. Wibowo
BPJS Kesehatan, the implementing body of the JKN Programme, is confronted with the challenge of maintaining program sustainability due to a significant number of inactive participants in the PBPU segment, a situation primarily attributed to the organization’s low brand equity. The primary research objective of this study is to To develop integrated marketing communication strategy to increase BPJS Kesehatan brand equity. The methodelogy used is qualitative and quantitative research. Despite possessing commendable competitive advantages and offering the most affordable healthcare options, BPJS Kesehatan’s struggle stems from deficiencies in marketing communication. Internally, the organization recognizes its potential to build brand equity but acknowledges a gap in marketing communication effectiveness and message coherence. Externally, the PBPU segment exhibits low brand equity, notably in terms of loyalty and awareness towards the JKN program. The identified target demographic for BPJS Kesehatan within the PBPU segment includes individuals aged 18-35, residing in urban and densely populated areas, with an upper-class socioeconomic status. While these individuals generally express trust in BPJS Kesehatan, they lack awareness of the program details. To address these challenges, a recommended strategy involves implementing an Integrated Marketing Communication approach with a specific theme: “ease of health insurance, which is reliable.” Key messages emphasizing affordability, accessibility, quality, value, convenience, technology, and social impact should be conveyed. Utilizing diverse marketing channels such as television, online video, social media campaigns, mobile app optimization, and events can enhance communication effectiveness. Additionally, BPJS Kesehatan should consider developing supplementary benefits to augment services and increase participant loyalty. It is also crucial to empower employees to serve as effective communicators, enhancing their assertive communication skills to bolster the organization’s overall communication strategy.
BPJS Kesehatan 是 JKN 计划的实施机构,由于 PBPU 部分有大量不活跃的参与者,该机构面临着维持计划可持续性的挑战,而造成这种情况的主要原因是该机构的品牌资产较低。本研究的主要目的是制定综合营销传播战略,以提高 BPJS Kesehatan 的品牌资产。采用的方法是定性和定量研究。尽管 BPJS Kesehatan 拥有值得称道的竞争优势,并提供最经济实惠的医疗保健选择,但其挣扎源于营销传播方面的不足。对内,该组织认识到自己在建立品牌资产方面的潜力,但也承认在营销传播的有效性和信息一致性方面存在差距。从外部来看,PBPU 部分的品牌资产较低,尤其是在对 JKN 计划的忠诚度和认知度方面。BPJS Kesehatan 在 PBPU 细分市场中确定的目标人群包括 18-35 岁、居住在城市和人口稠密地区、社会经济地位较高的个人。虽然这些人普遍对 BPJS Kesehatan 表示信任,但他们对计划的细节缺乏了解。为了应对这些挑战,建议采取的策略是实施以特定主题为中心的整合营销传播方法:"便捷、可靠的医疗保险"。应传达强调可负担性、可获得性、质量、价值、便利性、技术和社会影响的关键信息。利用多样化的营销渠道,如电视、在线视频、社交媒体宣传、移动应用程序优化和活动,可以提高传播效果。此外,BPJS Kesehatan 还应考虑开发补充福利,以增强服务并提高参与者的忠诚度。同样重要的是,要让员工成为有效的沟通者,提高他们自信的沟通技巧,以加强组织的整体沟通战略。
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引用次数: 0
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International Journal of Current Science Research and Review
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