Pub Date : 2020-08-01DOI: 10.6890/IJGE.202008_14(3).0017
Daewoo Lee, J. Yoo
Background: The purpose of this systematic review was to explore the association between masticatory function (subjective and objective assessment) and sarcopenia in elderly people. Methods: Multiple electronic databases including PubMed, Embase, Web of Science, and Cochrane Central Register of Controlled Trials were searched for all years up to October 1, 2019. Articles that evaluated occlusal force or chewing ability or difficulties in eating scores to explore the association between sarcopenia in elderly patients and healthy elderly peoples were included. A modified version of the Newcastle Ottawa Scale was used to assess study quality. The pooled standardized effect size with its corresponding 95% confidence interval for each parameter was calculated. Results: Of the 45 articles identified, three retrospective observational comparison studies, which had a lower risk of bias, were included: objective (occlusal force or chewing gum) and subjective (difficulties in eating scores) assessment were reported. Meta-analysis revealed that maximum occlusal force (standardized mean difference (SMD) = 0.36, confidence interval (CI) = 0.19-0.53, p ＜ 0.001)was significantly lower in subjects who were diagnosed with sarcopenia than in control groups. There were significant associations between sarcopenia and chewing ability using chewing gum (odds ratio (OR) = 2.34, CI = 1.09-5.02, p = 0.03) and difficulties in eating score (OR = 2.21, CI = 1.65-2.97, p ＜ 0.001). Conclusions: We found some limited evidence for an association between sarcopenia and masticatory function. Our meta-analysis supports an association between sarcopenia and subjective and objective masticatory function. More evidence is needed to demonstrate the association between masticatory function and sarcopenia in elderly people.
背景:本系统综述的目的是探讨老年人咀嚼功能(主观和客观评估)与肌肉减少症之间的关系。方法:检索截至2019年10月1日的所有年份的PubMed、Embase、Web of Science和Cochrane Central Register of Controlled Trials等多个电子数据库。纳入了评估咬合力、咀嚼能力或进食困难评分的文章，以探讨老年患者肌肉减少症与健康老年人之间的关系。采用改良版的纽卡斯尔渥太华量表来评估研究质量。计算每个参数的合并标准化效应大小及其相应的95%置信区间。结果:在纳入的45篇文章中，有3篇回顾性观察性比较研究(偏倚风险较低)被纳入:客观(咬合力或嚼口香糖)和主观(进食困难评分)评估。meta分析显示，肌少症患者的最大咬合力(标准化平均差(SMD) = 0.36，置信区间(CI) = 0.19-0.53, p < 0.001)显著低于对照组。肌肉减少症与嚼口香糖的咀嚼能力(比值比(OR) = 2.34, CI = 1.09-5.02, p = 0.03)和进食困难评分(OR = 2.21, CI = 1.65-2.97, p < 0.001)之间存在显著相关性。结论:我们发现一些有限的证据表明肌肉减少症与咀嚼功能之间存在关联。我们的荟萃分析支持肌肉减少症与主观和客观咀嚼功能之间的关联。需要更多的证据来证明老年人咀嚼功能和肌肉减少症之间的联系。
{"title":"Association between Masticatory Function and Sarcopenia in Elderly People: A Systematic Review and Meta-Analysis","authors":"Daewoo Lee, J. Yoo","doi":"10.6890/IJGE.202008_14(3).0017","DOIUrl":"https://doi.org/10.6890/IJGE.202008_14(3).0017","url":null,"abstract":"Background: The purpose of this systematic review was to explore the association between masticatory function (subjective and objective assessment) and sarcopenia in elderly people. Methods: Multiple electronic databases including PubMed, Embase, Web of Science, and Cochrane Central Register of Controlled Trials were searched for all years up to October 1, 2019. Articles that evaluated occlusal force or chewing ability or difficulties in eating scores to explore the association between sarcopenia in elderly patients and healthy elderly peoples were included. A modified version of the Newcastle Ottawa Scale was used to assess study quality. The pooled standardized effect size with its corresponding 95% confidence interval for each parameter was calculated. Results: Of the 45 articles identified, three retrospective observational comparison studies, which had a lower risk of bias, were included: objective (occlusal force or chewing gum) and subjective (difficulties in eating scores) assessment were reported. Meta-analysis revealed that maximum occlusal force (standardized mean difference (SMD) = 0.36, confidence interval (CI) = 0.19-0.53, p ＜ 0.001)was significantly lower in subjects who were diagnosed with sarcopenia than in control groups. There were significant associations between sarcopenia and chewing ability using chewing gum (odds ratio (OR) = 2.34, CI = 1.09-5.02, p = 0.03) and difficulties in eating score (OR = 2.21, CI = 1.65-2.97, p ＜ 0.001). Conclusions: We found some limited evidence for an association between sarcopenia and masticatory function. Our meta-analysis supports an association between sarcopenia and subjective and objective masticatory function. More evidence is needed to demonstrate the association between masticatory function and sarcopenia in elderly people.","PeriodicalId":50321,"journal":{"name":"International Journal of Gerontology","volume":"4 1","pages":"238-244"},"PeriodicalIF":0.3,"publicationDate":"2020-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84727570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-08-01DOI: 10.6890/IJGE.202008_14(3).0006
Chang-Wan Kim, Y. Choi, Keon Kim
Background: Suicide is a major cause of death worldwide. While studies have been conducted on the predictors of suicide behaviors, these have not covered how lethality and the various predictors differ by age. We explored these age differences in the present study. Methods: We retrospectively reviewed the medical records of suicidal patients in the emergency department (ED) of a university hospital in Seoul, South Korea, between September 2017 and August 2018. We extracted participants' data from the National Emergency Department Information System of Korea and their individual electronic medical records (EMRs), including demographic information (e.g., age, gender), details of their ED visit (e.g., suicide method), and medical history (e.g., physical illness, alcohol co-ingestion).We also used EMR data to complete the Risk-Rescue Rating Scale (RRRS). Results: Of the 499 patients referred to the ED for suicide attempts, 427 were analyzed.We found that while younger participants were more likely to have repeated attempts, older participants' attempts were more likely to be fatal (e.g., higher RRRS risk scores and lower accessibility-to-rescue scores). After adjusting for demographics, older participants showed significantly higher scores on RRRS risk, impaired consciousness, and treatment required than younger participants. Conclusion: Our findings clarified the characteristics of high-risk suicide attempters based onage, which could influence suicide-prevention policies (e.g., younger people tend to repeat suicide attempts, and thus may require continued surveillance). However, as older adults showed higher lethality and were more difficult to save, they may require suicide prevention coupled with social support interventions.
{"title":"Characteristics and Lethality of Suicide Attempters by Age Group in Korea: Retrospective Single-Centered Study","authors":"Chang-Wan Kim, Y. Choi, Keon Kim","doi":"10.6890/IJGE.202008_14(3).0006","DOIUrl":"https://doi.org/10.6890/IJGE.202008_14(3).0006","url":null,"abstract":"Background: Suicide is a major cause of death worldwide. While studies have been conducted on the predictors of suicide behaviors, these have not covered how lethality and the various predictors differ by age. We explored these age differences in the present study. Methods: We retrospectively reviewed the medical records of suicidal patients in the emergency department (ED) of a university hospital in Seoul, South Korea, between September 2017 and August 2018. We extracted participants' data from the National Emergency Department Information System of Korea and their individual electronic medical records (EMRs), including demographic information (e.g., age, gender), details of their ED visit (e.g., suicide method), and medical history (e.g., physical illness, alcohol co-ingestion).We also used EMR data to complete the Risk-Rescue Rating Scale (RRRS). Results: Of the 499 patients referred to the ED for suicide attempts, 427 were analyzed.We found that while younger participants were more likely to have repeated attempts, older participants' attempts were more likely to be fatal (e.g., higher RRRS risk scores and lower accessibility-to-rescue scores). After adjusting for demographics, older participants showed significantly higher scores on RRRS risk, impaired consciousness, and treatment required than younger participants. Conclusion: Our findings clarified the characteristics of high-risk suicide attempters based onage, which could influence suicide-prevention policies (e.g., younger people tend to repeat suicide attempts, and thus may require continued surveillance). However, as older adults showed higher lethality and were more difficult to save, they may require suicide prevention coupled with social support interventions.","PeriodicalId":50321,"journal":{"name":"International Journal of Gerontology","volume":"88 1","pages":"179-184"},"PeriodicalIF":0.3,"publicationDate":"2020-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73625560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-08-01DOI: 10.6890/IJGE.202008_14(3).0001
Chih-Ning Chang, N. Ko, Yu-Ning Hu, G. Hu
Knee osteoarthritis (KOA) is the most common form of arthritis and one of the leading causes of disability. OA is characterized by cartilage damage, subchondral bone changes, and synovial tissue inflammation, with clinical symptoms of pain, decreased range of motion (ROM) and functional impairment. Recently, extracorporeal shockwave therapy (ESWT) has been introduced in the treatment of OA and there is increasing evidence of the therapeutic effects of ESWT on patients with KOA. For decades, there have been multiple attempts to understand the mechanisms of these therapeutic effects. So far, it is appreciated that cellular mechanotransduction through the cytoskeleton into the nuclei can regulate gene expression and cause biological changes. The purpose of this article is to provide current evidence on the physical and biological principles, mechanism of action and clinical efficacy of ESWT on KOA.
{"title":"Extracorporeal Shock Wave Therapy in the Treatment of Knee Osteoarthritis: A Review of Mechanism of Action and Clinical Efficacy","authors":"Chih-Ning Chang, N. Ko, Yu-Ning Hu, G. Hu","doi":"10.6890/IJGE.202008_14(3).0001","DOIUrl":"https://doi.org/10.6890/IJGE.202008_14(3).0001","url":null,"abstract":"Knee osteoarthritis (KOA) is the most common form of arthritis and one of the leading causes of disability. OA is characterized by cartilage damage, subchondral bone changes, and synovial tissue inflammation, with clinical symptoms of pain, decreased range of motion (ROM) and functional impairment. Recently, extracorporeal shockwave therapy (ESWT) has been introduced in the treatment of OA and there is increasing evidence of the therapeutic effects of ESWT on patients with KOA. For decades, there have been multiple attempts to understand the mechanisms of these therapeutic effects. So far, it is appreciated that cellular mechanotransduction through the cytoskeleton into the nuclei can regulate gene expression and cause biological changes. The purpose of this article is to provide current evidence on the physical and biological principles, mechanism of action and clinical efficacy of ESWT on KOA.","PeriodicalId":50321,"journal":{"name":"International Journal of Gerontology","volume":"6 1","pages":"154-158"},"PeriodicalIF":0.3,"publicationDate":"2020-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80242380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-08-01DOI: 10.6890/IJGE.202008_14(3).0015
X. Lv, Wenyan Gao, Guo-Fu Wang, B. Jia, Jing Zhang, Jirong Wang, Wenmin Xing, Jing Yan
Background: The role of bone metabolism markers for identifying the severity of chronic heart failure (CHF) in elderly adults had not been comprehensively investigated. Methods: 335 elderly patients (mean age 83.98 years, women 36.72%) were divided into mild CHF (NYHA class I+II) group and severe CHF (NYHA class III+IV) group. We performed a binary logistic regression analysis to identify the independent association of bone metabolism markers with the severity of CHF. Besides, we used ROC curve to explore the predictability of bone metabolism markers on CHF severity. Results: BMD levels of femoral neck in severe CHF group were significantly lower than that in mild CHF group with no gender difference. However, CTX-I, OC, PINP, ALP and PTH levels were significantly increased only in women with severe CHF. CTX-I (OR = 1.003, p = 0.008) was identified as an independent influencing factor positively associated with the severity of CHF in women after controlling for covariates. The predictability of CTX-I, OC, PINP and ALP for CHF severity was superior to NT-proBNP. Conclusion: The association between bone metabolism and CHF severity varied by genders. Bone metabolism markers, especially the CTX-I, might be a possible risk marker associated with CHF severity independent of NT-proBNP in women.
{"title":"Association between Bone Metabolism and the Severity of Chronic Heart Failure in Chinese Elderly Men and Women","authors":"X. Lv, Wenyan Gao, Guo-Fu Wang, B. Jia, Jing Zhang, Jirong Wang, Wenmin Xing, Jing Yan","doi":"10.6890/IJGE.202008_14(3).0015","DOIUrl":"https://doi.org/10.6890/IJGE.202008_14(3).0015","url":null,"abstract":"Background: The role of bone metabolism markers for identifying the severity of chronic heart failure (CHF) in elderly adults had not been comprehensively investigated. Methods: 335 elderly patients (mean age 83.98 years, women 36.72%) were divided into mild CHF (NYHA class I+II) group and severe CHF (NYHA class III+IV) group. We performed a binary logistic regression analysis to identify the independent association of bone metabolism markers with the severity of CHF. Besides, we used ROC curve to explore the predictability of bone metabolism markers on CHF severity. Results: BMD levels of femoral neck in severe CHF group were significantly lower than that in mild CHF group with no gender difference. However, CTX-I, OC, PINP, ALP and PTH levels were significantly increased only in women with severe CHF. CTX-I (OR = 1.003, p = 0.008) was identified as an independent influencing factor positively associated with the severity of CHF in women after controlling for covariates. The predictability of CTX-I, OC, PINP and ALP for CHF severity was superior to NT-proBNP. Conclusion: The association between bone metabolism and CHF severity varied by genders. Bone metabolism markers, especially the CTX-I, might be a possible risk marker associated with CHF severity independent of NT-proBNP in women.","PeriodicalId":50321,"journal":{"name":"International Journal of Gerontology","volume":"33 1","pages":"227-232"},"PeriodicalIF":0.3,"publicationDate":"2020-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77305006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-08-01DOI: 10.6890/IJGE.202008_14(3).0020
Yi-Chung Yu, Wei-Kee Huang
Gastric volvulus is defined as the rotation of the hollow viscus around its mesentery. The classic symptoms, known as “Borchardt’s triad” consist of nonproductive vomiting, severe and constant epigastric pain, and difficulty inserting a nasogastric tube; however, these may not be present in as many as 25% of the patients. The mortality rate of 30–50 % is reported. It should be differentiated from myocardial infarction, perforated peptic ulcer, and abdominal apoplexy.
{"title":"Acute Gastric Volvulus: A Deadly Surgical Condition at Emergency Department","authors":"Yi-Chung Yu, Wei-Kee Huang","doi":"10.6890/IJGE.202008_14(3).0020","DOIUrl":"https://doi.org/10.6890/IJGE.202008_14(3).0020","url":null,"abstract":"Gastric volvulus is defined as the rotation of the hollow viscus around its mesentery. The classic symptoms, known as “Borchardt’s triad” consist of nonproductive vomiting, severe and constant epigastric pain, and difficulty inserting a nasogastric tube; however, these may not be present in as many as 25% of the patients. The mortality rate of 30–50 % is reported. It should be differentiated from myocardial infarction, perforated peptic ulcer, and abdominal apoplexy.","PeriodicalId":50321,"journal":{"name":"International Journal of Gerontology","volume":"145 1","pages":"253-253"},"PeriodicalIF":0.3,"publicationDate":"2020-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78588216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-08-01DOI: 10.6890/IJGE.202008_14(3).0011
Takuma Yasuda, T. Murakami, Y. Ueba, H. Fujita, Masaki Fujimura, Tomonobu Hatoko, Y. Kanai, Eisaku Mori, S. Yonemitsu, S. Oki, Seiji Muro
Background: Assessing cognitive function and the risk of hypoglycemia among older individuals with diabetes is an ongoing challenge. Although the Japan Diabetes Society/Japan Geriatrics Society Joint Committee has already provided recommendations for glycemic control in older individuals with diabetes, its usefulness in clinical settings remains unclear. Methods: A retrospective, single-center study was conducted on 616 outpatients aged over 65 years at Osaka Red Cross Hospital, Japan. They were assessed for glycemic control and cognitive function using the Dementia Assessment Sheet for Community-based Integrated Care System 21-items (DASC-21). Patients were categorized into three groups based on cognitive function, and each group was divided into six subcategories based on recommended therapeutic regimens. Results: Ninety-eight patients treated with insulin, sulfonylurea, or glinide were identified using DASC- 21 and classified into categories IIB and IIIB. The number of hypoglycemic events was divided according to the lower limit of the recommended glycohemoglobin (HbA1c) value. However, the results did not significantly differ. Notably, in 7 of 9 IIIB patients who with hypoglycemic events, their DASC-21 scores reached up to 36. This suggests that the physicians had not identified the risk of dementia before conducting the assessment using DASC-21, which might result in continuous therapy for diabetes including daily multiple insulin injections. Conclusions: Physicians can overlook the risk of hypoglycemia and cognitive impairment thereby failing to optimize diabetic therapies among older individuals if DASC-21 is not used during assessments in daily diabetic care.
{"title":"Identification of Undetected Dementia and Hypoglycemic Risk Using the Dementia Assessment Sheet for Community-Based Integrated Care System 21-Items in the Glycohemoglobin-Guided Management of Elderly Individuals with Diabetes: An Exploratory Study","authors":"Takuma Yasuda, T. Murakami, Y. Ueba, H. Fujita, Masaki Fujimura, Tomonobu Hatoko, Y. Kanai, Eisaku Mori, S. Yonemitsu, S. Oki, Seiji Muro","doi":"10.6890/IJGE.202008_14(3).0011","DOIUrl":"https://doi.org/10.6890/IJGE.202008_14(3).0011","url":null,"abstract":"Background: Assessing cognitive function and the risk of hypoglycemia among older individuals with diabetes is an ongoing challenge. Although the Japan Diabetes Society/Japan Geriatrics Society Joint Committee has already provided recommendations for glycemic control in older individuals with diabetes, its usefulness in clinical settings remains unclear. Methods: A retrospective, single-center study was conducted on 616 outpatients aged over 65 years at Osaka Red Cross Hospital, Japan. They were assessed for glycemic control and cognitive function using the Dementia Assessment Sheet for Community-based Integrated Care System 21-items (DASC-21). Patients were categorized into three groups based on cognitive function, and each group was divided into six subcategories based on recommended therapeutic regimens. Results: Ninety-eight patients treated with insulin, sulfonylurea, or glinide were identified using DASC- 21 and classified into categories IIB and IIIB. The number of hypoglycemic events was divided according to the lower limit of the recommended glycohemoglobin (HbA1c) value. However, the results did not significantly differ. Notably, in 7 of 9 IIIB patients who with hypoglycemic events, their DASC-21 scores reached up to 36. This suggests that the physicians had not identified the risk of dementia before conducting the assessment using DASC-21, which might result in continuous therapy for diabetes including daily multiple insulin injections. Conclusions: Physicians can overlook the risk of hypoglycemia and cognitive impairment thereby failing to optimize diabetic therapies among older individuals if DASC-21 is not used during assessments in daily diabetic care.","PeriodicalId":50321,"journal":{"name":"International Journal of Gerontology","volume":"14 1","pages":"207-211"},"PeriodicalIF":0.3,"publicationDate":"2020-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85532890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-08-01DOI: 10.6890/IJGE.202008_14(3).0016
E. Akyuz, O. Ekinci
Background: There is a lack of information about the factors that affect depression in hospitalized geriatric patients with malnutrition. We aimed to determine the risk and influencing factors of depression in these patients. Methods: The prospective, descriptive study was conducted on 125 elderly patients with malnutrition in Istanbul, Turkey in 2018. The Mini Nutritional Assessment-short form was used in determining the nutritional statuses of the participants, and the Geriatric Depression Scale-short form was used for the status of depression. Results: A negative relationship was found between nutritional status and risk of depression in the study (p: 0.000; r: -0.558). Depression was detected in 52.8% of the patients. 60.8% were women and 39.2% were men. It was also found that BMI scores, gender, marital status, level of education, lifestyle and location, the existence of chronic diseases, chronic medication use, hospital stay period, and mobilization affect the emergence and severity of depression in geriatric patients (p ＜ 0.005). Multivariate regression analysis showed that increased risk of depression occurs with female gender (OR: 24.665, 95% CI: 5.83-104.34), marital status (OR = 11.97, 95% CI: 3.51-40.86), mobilization (OR: 9.52, 95% CI: 1.79-50.71) and malnutrition (OR = 0.49, 95% CI: 0.27-0.89). Conclusions: Depression was frequent in elderly patients with malnutrition. Also, many factors (e.g. low BMI, female gender, mobilization etc.) affect it in hospital. Therefore, close follow-up of patients is important.
{"title":"Risk Factors for Depression in Hospitalized Elderly Patients with Malnutrition","authors":"E. Akyuz, O. Ekinci","doi":"10.6890/IJGE.202008_14(3).0016","DOIUrl":"https://doi.org/10.6890/IJGE.202008_14(3).0016","url":null,"abstract":"Background: There is a lack of information about the factors that affect depression in hospitalized geriatric patients with malnutrition. We aimed to determine the risk and influencing factors of depression in these patients. Methods: The prospective, descriptive study was conducted on 125 elderly patients with malnutrition in Istanbul, Turkey in 2018. The Mini Nutritional Assessment-short form was used in determining the nutritional statuses of the participants, and the Geriatric Depression Scale-short form was used for the status of depression. Results: A negative relationship was found between nutritional status and risk of depression in the study (p: 0.000; r: -0.558). Depression was detected in 52.8% of the patients. 60.8% were women and 39.2% were men. It was also found that BMI scores, gender, marital status, level of education, lifestyle and location, the existence of chronic diseases, chronic medication use, hospital stay period, and mobilization affect the emergence and severity of depression in geriatric patients (p ＜ 0.005). Multivariate regression analysis showed that increased risk of depression occurs with female gender (OR: 24.665, 95% CI: 5.83-104.34), marital status (OR = 11.97, 95% CI: 3.51-40.86), mobilization (OR: 9.52, 95% CI: 1.79-50.71) and malnutrition (OR = 0.49, 95% CI: 0.27-0.89). Conclusions: Depression was frequent in elderly patients with malnutrition. Also, many factors (e.g. low BMI, female gender, mobilization etc.) affect it in hospital. Therefore, close follow-up of patients is important.","PeriodicalId":50321,"journal":{"name":"International Journal of Gerontology","volume":"206 1","pages":"233-237"},"PeriodicalIF":0.3,"publicationDate":"2020-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77059700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-08-01DOI: 10.6890/IJGE.202008_14(3).0010
Shiqi Wen, Quan-jing Chen, Wanli Sun
Background: Lower extremity atherosclerotic disease (LEAD) is a common disease in elderly, and it is closely related to many risk factors. The oxidative stress is involved in the arteriosclerosis. This study aimed to investigate the changes of oxidative stress indexes in patients with LEAD, and discuss their relations with the disease severity and the complications. Methods: Eighty-three LEAD patients and 40 subjects without LEAD (control group) were enrolled. The ankle-brachial index (ABI) was measured. The serum superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and malondialdehyde (MDA) levels were determined. Results: The serum SOD and GSH-Px levels and ABI in LEAD group were significantly lower than those in control group, respectively (p ＜ 0.01), while the serum MDA level in LEAD groupwas significantly higher than that in control group (p ＜ 0.01). There was significant difference of SOD, GSH-Px, MDA and ABI among LEAD patients with different stages, respectively (p ＜ 0.01), with significant difference of each index between LEAD patients with and without hypertension, with and without diabetes, and with and without hyperlipemia, respectively (p ＜ 0.01). In LEAD patients, there was positive correlation between SOD and ABI and between GSH-Px and ABI, respectively, with negative correlation between SOD and MDA, between GSH-Px and MDA and between MDA and ABI, respectively (p ＜ 0.01). Conclusion: The changes of serum SOD, GSH-Px and MDA levels are involved in the occurrence and development of LEAD. These indexes are helpful for the diagnosis of the LEAD severity and the complications.
{"title":"Oxidative Stress is Involved in the Occurrence and Development of Lower Extremity Atherosclerotic Disease","authors":"Shiqi Wen, Quan-jing Chen, Wanli Sun","doi":"10.6890/IJGE.202008_14(3).0010","DOIUrl":"https://doi.org/10.6890/IJGE.202008_14(3).0010","url":null,"abstract":"Background: Lower extremity atherosclerotic disease (LEAD) is a common disease in elderly, and it is closely related to many risk factors. The oxidative stress is involved in the arteriosclerosis. This study aimed to investigate the changes of oxidative stress indexes in patients with LEAD, and discuss their relations with the disease severity and the complications. Methods: Eighty-three LEAD patients and 40 subjects without LEAD (control group) were enrolled. The ankle-brachial index (ABI) was measured. The serum superoxide dismutase (SOD), glutathione peroxidase (GSH-Px) and malondialdehyde (MDA) levels were determined. Results: The serum SOD and GSH-Px levels and ABI in LEAD group were significantly lower than those in control group, respectively (p ＜ 0.01), while the serum MDA level in LEAD groupwas significantly higher than that in control group (p ＜ 0.01). There was significant difference of SOD, GSH-Px, MDA and ABI among LEAD patients with different stages, respectively (p ＜ 0.01), with significant difference of each index between LEAD patients with and without hypertension, with and without diabetes, and with and without hyperlipemia, respectively (p ＜ 0.01). In LEAD patients, there was positive correlation between SOD and ABI and between GSH-Px and ABI, respectively, with negative correlation between SOD and MDA, between GSH-Px and MDA and between MDA and ABI, respectively (p ＜ 0.01). Conclusion: The changes of serum SOD, GSH-Px and MDA levels are involved in the occurrence and development of LEAD. These indexes are helpful for the diagnosis of the LEAD severity and the complications.","PeriodicalId":50321,"journal":{"name":"International Journal of Gerontology","volume":"2 1","pages":"202-206"},"PeriodicalIF":0.3,"publicationDate":"2020-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90137603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-08-01DOI: 10.6890/IJGE.202008_14(3).0018
O. Ozger, Necati Kaplan
Background: Lumbar microdiscectomy is considered the gold standard in the surgical treatment of patients with lumbar disc herniation. This study evaluated the clinical outcomes of lumbar microdiscectomy in geriatric patients who underwent surgery in our clinic and determined whether there was a significant difference in clinical outcomes between the two genders in this population. Methods: This study included 60 geriatric patients aged ≥ 65 years who underwent lumbar microdiscectomy between April 2015 and May 2019 for lumbar disc herniation. Preoperative and postoperative visual analog scale and Oswestry Disability Index scores were calculated and compared separately for both genders. Statistical analyses were performed using statistical package for the social sciences version 22.0 software. Results: The mean age of the patients was 72.22 ± 6.06 years and the mean length of stay in the operating room and hospital were 172.83 ± 37.19 min and 1643.18 ± 647.05 min, respectively. Although there was a significant decrease in postoperative visual analog scale and Oswestry Disability Index scores compared to preoperative scores, no significant difference was observed between the genders. The success rate for excellent or good results according to the modified Macnab criteria was 91.66% in all groups. Conclusion: In the surgical treatment of geriatric patients with lumbar disc herniation, lumbar microdiscectomy is an effective and safe method since it is associated with low complication rates and high success rates. No significant difference was found between genders in terms of clinical outcomes in this age group.
{"title":"Evaluation of the Clinical Outcomes of Lumbar Microdiscectomy in Both Gender of Geriatric Patients Aged ≥ 65 Years","authors":"O. Ozger, Necati Kaplan","doi":"10.6890/IJGE.202008_14(3).0018","DOIUrl":"https://doi.org/10.6890/IJGE.202008_14(3).0018","url":null,"abstract":"Background: Lumbar microdiscectomy is considered the gold standard in the surgical treatment of patients with lumbar disc herniation. This study evaluated the clinical outcomes of lumbar microdiscectomy in geriatric patients who underwent surgery in our clinic and determined whether there was a significant difference in clinical outcomes between the two genders in this population. Methods: This study included 60 geriatric patients aged ≥ 65 years who underwent lumbar microdiscectomy between April 2015 and May 2019 for lumbar disc herniation. Preoperative and postoperative visual analog scale and Oswestry Disability Index scores were calculated and compared separately for both genders. Statistical analyses were performed using statistical package for the social sciences version 22.0 software. Results: The mean age of the patients was 72.22 ± 6.06 years and the mean length of stay in the operating room and hospital were 172.83 ± 37.19 min and 1643.18 ± 647.05 min, respectively. Although there was a significant decrease in postoperative visual analog scale and Oswestry Disability Index scores compared to preoperative scores, no significant difference was observed between the genders. The success rate for excellent or good results according to the modified Macnab criteria was 91.66% in all groups. Conclusion: In the surgical treatment of geriatric patients with lumbar disc herniation, lumbar microdiscectomy is an effective and safe method since it is associated with low complication rates and high success rates. No significant difference was found between genders in terms of clinical outcomes in this age group.","PeriodicalId":50321,"journal":{"name":"International Journal of Gerontology","volume":"23 1","pages":"245-250"},"PeriodicalIF":0.3,"publicationDate":"2020-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91233615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-08-01DOI: 10.6890/IJGE.202008_14(3).0005
I-Ju Chen, Y. Chuang, L. Hsu, Jau-Yuan Chen
Background: The main aim of this study was to explore whether the risk of chronic kidney disease (CKD) varies by marital status among men and women aged 50 years and older in Taiwan. Methods: The study data were gathered from health exams in communities of northern Taiwan from January to October 2014. In this study, people who were divorced, separated, widowed, or never married were categorized as currently single. Those who lived with their mate regardless of married or not were categorized as currently couple. We used chi-square test and a multiple logistic regression model to evaluate the association between CKD and different marital status. Other factors for CKD, including sex, age, smoking, body mass index (BMI), systolic blood pressure (SBP), heart rate, fasting plasma glucose (FPG), triglyceride (TG), uric acid, occupation, and source of income were adjusted. Results: A total of 400 participants were enrolled in this study (35.3% male and 64.8% female), with a mean age of 64.47 ± 8.45 years. Among them, 19% (n = 76) were categorized as currently single. The prevalence of CKD was higher in single status (31.58%) than in couple status (17.59%) (p value = 0.01). Multiple logistic regression analysis indicated an independent association of marital status and CKD (odds ratio [OR] = 2.14, 95% confidence interval [CI]: 1.12-4.09, p = 0.02) after adjusting for other confounding factors. Conclusions: Marital status is associated with CKD in middle-aged and elderly Taiwanese population. Single status is an independent risk factor for CKD.
{"title":"Association between Marital Status and Chronic Kidney Disease among Middle-Aged and Elderly Taiwanese: A Community-Based, Cross-Sectional Study","authors":"I-Ju Chen, Y. Chuang, L. Hsu, Jau-Yuan Chen","doi":"10.6890/IJGE.202008_14(3).0005","DOIUrl":"https://doi.org/10.6890/IJGE.202008_14(3).0005","url":null,"abstract":"Background: The main aim of this study was to explore whether the risk of chronic kidney disease (CKD) varies by marital status among men and women aged 50 years and older in Taiwan. Methods: The study data were gathered from health exams in communities of northern Taiwan from January to October 2014. In this study, people who were divorced, separated, widowed, or never married were categorized as currently single. Those who lived with their mate regardless of married or not were categorized as currently couple. We used chi-square test and a multiple logistic regression model to evaluate the association between CKD and different marital status. Other factors for CKD, including sex, age, smoking, body mass index (BMI), systolic blood pressure (SBP), heart rate, fasting plasma glucose (FPG), triglyceride (TG), uric acid, occupation, and source of income were adjusted. Results: A total of 400 participants were enrolled in this study (35.3% male and 64.8% female), with a mean age of 64.47 ± 8.45 years. Among them, 19% (n = 76) were categorized as currently single. The prevalence of CKD was higher in single status (31.58%) than in couple status (17.59%) (p value = 0.01). Multiple logistic regression analysis indicated an independent association of marital status and CKD (odds ratio [OR] = 2.14, 95% confidence interval [CI]: 1.12-4.09, p = 0.02) after adjusting for other confounding factors. Conclusions: Marital status is associated with CKD in middle-aged and elderly Taiwanese population. Single status is an independent risk factor for CKD.","PeriodicalId":50321,"journal":{"name":"International Journal of Gerontology","volume":"34 1","pages":"174-178"},"PeriodicalIF":0.3,"publicationDate":"2020-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74310479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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