Pub Date : 2021-01-01DOI: 10.6890/IJGE.202101_15(1).0009
Y. Ha, J. Yoo, K. Park, R. Kim, Sung-Hyo Seo
Purpose: The purpose of this study was to analyze the association between mortality and the prevalence of delirium in patients with hip fracture using national claim data. Method: This cohort study was conducted from 2010 to 2013, including diagnostic criteria for hip fractures (femoral neck fractures or femur fractures) over 50 years of age. Operational definitions of delirium include disease code and drug use. The mortality rate was calculated using the Charlson's comorbidity index and statistically analyzed using the Cox proportional hazards regression analysis. Results: A total of 1,587 patients, 209 patients (13.2%) had delirium during hospitalization (66 (31.6%) in males, 143 (68.4%) in females). After adjusting for the comorbidity index, the mortality rate in patients with postoperative delirium was 1.42 times higher than for the patients without delirium during over a mean 17-month follow-up (HR = 1.42, 95% CI; 1.07-1.87, p = 0.007). During the follow-up duration at four years, the cumulative mortality rates were higher in the delirium group (24.3% at one year, 31.8% at two years, 35.8% at three years, and 37.8% at four years, respectively) than in the non-delirium group (14.8% at one year, 21.7% at two years, 24.9% at three years, and 25.5% at four years, respectively). Conclusion: In this nationwide study, the prevalence of delirium during the hospital stay after hip fracture surgery was 13.2% and the mortality rate in patients with postoperative delirium was 1.42 times higher than for the patients without delirium during a mean 17-month follow-up.
目的:本研究的目的是利用国家索赔数据分析髋部骨折患者谵妄患病率与死亡率之间的关系。方法:本队列研究于2010 - 2013年进行，纳入50岁以上髋部骨折(股骨颈骨折或股骨骨折)的诊断标准。谵妄的操作定义包括疾病代码和药物使用。死亡率采用Charlson合并症指数计算，并采用Cox比例风险回归分析进行统计学分析。结果:共1587例患者，住院期间出现谵妄209例(13.2%)，其中男性66例(31.6%)，女性143例(68.4%)。在调整合并症指数后，在平均17个月的随访中，术后谵妄患者的死亡率是无谵妄患者的1.42倍(HR = 1.42, 95% CI;1.07-1.87, p = 0.007)。在4年随访期间，谵妄组的累积死亡率(1年24.3%，2年31.8%，3年35.8%，4年37.8%)高于非谵妄组(1年14.8%，2年21.7%，3年24.9%，4年25.5%)。结论:在这项全国性的研究中，髋部骨折术后住院期间谵妄的患病率为13.2%，术后谵妄患者的死亡率是无谵妄患者的1.42倍，平均随访17个月。
{"title":"Delirium in Patient with Hip Fracture is Related High Mortality: A National Cohort Study","authors":"Y. Ha, J. Yoo, K. Park, R. Kim, Sung-Hyo Seo","doi":"10.6890/IJGE.202101_15(1).0009","DOIUrl":"https://doi.org/10.6890/IJGE.202101_15(1).0009","url":null,"abstract":"Purpose: The purpose of this study was to analyze the association between mortality and the prevalence of delirium in patients with hip fracture using national claim data. Method: This cohort study was conducted from 2010 to 2013, including diagnostic criteria for hip fractures (femoral neck fractures or femur fractures) over 50 years of age. Operational definitions of delirium include disease code and drug use. The mortality rate was calculated using the Charlson's comorbidity index and statistically analyzed using the Cox proportional hazards regression analysis. Results: A total of 1,587 patients, 209 patients (13.2%) had delirium during hospitalization (66 (31.6%) in males, 143 (68.4%) in females). After adjusting for the comorbidity index, the mortality rate in patients with postoperative delirium was 1.42 times higher than for the patients without delirium during over a mean 17-month follow-up (HR = 1.42, 95% CI; 1.07-1.87, p = 0.007). During the follow-up duration at four years, the cumulative mortality rates were higher in the delirium group (24.3% at one year, 31.8% at two years, 35.8% at three years, and 37.8% at four years, respectively) than in the non-delirium group (14.8% at one year, 21.7% at two years, 24.9% at three years, and 25.5% at four years, respectively). Conclusion: In this nationwide study, the prevalence of delirium during the hospital stay after hip fracture surgery was 13.2% and the mortality rate in patients with postoperative delirium was 1.42 times higher than for the patients without delirium during a mean 17-month follow-up.","PeriodicalId":50321,"journal":{"name":"International Journal of Gerontology","volume":"30 1","pages":"45-48"},"PeriodicalIF":0.3,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86238735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.6890/IJGE.202101_15(1).0012
Chen-I Shih, Y. Hsu, Hui-Fei Yang, Hsi-Lung Hung, S. Chia, Ying-Wei Wang, Wei Chen, Sheng-Yu Fan
{"title":"Development of an Age-Friendly Health Service Recognition Framework for Primary Health Centers in Taiwan","authors":"Chen-I Shih, Y. Hsu, Hui-Fei Yang, Hsi-Lung Hung, S. Chia, Ying-Wei Wang, Wei Chen, Sheng-Yu Fan","doi":"10.6890/IJGE.202101_15(1).0012","DOIUrl":"https://doi.org/10.6890/IJGE.202101_15(1).0012","url":null,"abstract":"","PeriodicalId":50321,"journal":{"name":"International Journal of Gerontology","volume":"115 1","pages":"58-63"},"PeriodicalIF":0.3,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80808610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.6890/IJGE.202101_15(1).EC
J. Kuo, C. Hung
{"title":"Albumin Level and Physical Integrity","authors":"J. Kuo, C. Hung","doi":"10.6890/IJGE.202101_15(1).EC","DOIUrl":"https://doi.org/10.6890/IJGE.202101_15(1).EC","url":null,"abstract":"","PeriodicalId":50321,"journal":{"name":"International Journal of Gerontology","volume":"359 1","pages":"1-1"},"PeriodicalIF":0.3,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76410138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.6890/IJGE.202101_15(1).0001
Chieh-Wen Chen
Obesity and intermittent hypoxia (IH) occurring during obstructive sleep apnea (OSA) are two independent risk factors for impaired ventricular function; cardiac dysfunction is exacerbated when the two factors co-occur. Regular exercise provides beneficial effects to attenuate cardiac fibrosis by reducing body fat percentage and preventing adipokine dysregulation. However, the mechanisms by which myokines, muscle-derived factors released during exercise, play a role in the prevention of IH-induced cardiac dysfunction, are still unclear. This study investigates the effects of myokines on ventricular dysfunction. The important role that myokines play in cardiac function in patients with OSA is discussed in the literature review. The conclusion of this study is that in obese individuals, excess adipose tissues trigger the dysregulation of adipokines. This dysregulation leads to myocardial inflammation, resulting in left ventricular dysfunction. Physical activity induces an increase in energy expenditure and triggers the release of myokines into the circulation by skeletal muscles, accelerating lipid metabolism, and improving the altered secretion profiles of adipokines. This process helps to alleviate myocardial inflammation and prevents the impairment of ventricular function. The paper suggests that future studies can investigate the effects of myokines on lipid metabolism, including how to reduce fat deposition and alleviate inflammation efficiently. In effect, muscle-derived cytokines (myokines) can be considered as anti-inflammatory mediators. This similarity provides support for advocating that regular exercise provides cardioprotective effects against cardiac function impairment in obese patients with OSA.
{"title":"Effects of Exercise on Myocardial Damage and Heart Failure Due to Hypoxia Induced by Obstructive Sleep Apnea","authors":"Chieh-Wen Chen","doi":"10.6890/IJGE.202101_15(1).0001","DOIUrl":"https://doi.org/10.6890/IJGE.202101_15(1).0001","url":null,"abstract":"Obesity and intermittent hypoxia (IH) occurring during obstructive sleep apnea (OSA) are two independent risk factors for impaired ventricular function; cardiac dysfunction is exacerbated when the two factors co-occur. Regular exercise provides beneficial effects to attenuate cardiac fibrosis by reducing body fat percentage and preventing adipokine dysregulation. However, the mechanisms by which myokines, muscle-derived factors released during exercise, play a role in the prevention of IH-induced cardiac dysfunction, are still unclear. This study investigates the effects of myokines on ventricular dysfunction. The important role that myokines play in cardiac function in patients with OSA is discussed in the literature review. The conclusion of this study is that in obese individuals, excess adipose tissues trigger the dysregulation of adipokines. This dysregulation leads to myocardial inflammation, resulting in left ventricular dysfunction. Physical activity induces an increase in energy expenditure and triggers the release of myokines into the circulation by skeletal muscles, accelerating lipid metabolism, and improving the altered secretion profiles of adipokines. This process helps to alleviate myocardial inflammation and prevents the impairment of ventricular function. The paper suggests that future studies can investigate the effects of myokines on lipid metabolism, including how to reduce fat deposition and alleviate inflammation efficiently. In effect, muscle-derived cytokines (myokines) can be considered as anti-inflammatory mediators. This similarity provides support for advocating that regular exercise provides cardioprotective effects against cardiac function impairment in obese patients with OSA.","PeriodicalId":50321,"journal":{"name":"International Journal of Gerontology","volume":"57 1","pages":"2-6"},"PeriodicalIF":0.3,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79845753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-11-01DOI: 10.6890/IJGE.202011_14(4).0011
T. Czernicki, P. Kunert, A. Nowak, J. Żyłkowski, M. Jaworski, A. Marchel
Background: Management of unruptured intracranial aneurysms (UIA) in elderly patients is controversial, taking into consideration their limited life-expectancy and existing comorbidities. With advances in endovascular techniques, we decided to evaluate treatment results in this population and to assess results in surgically and endovascularly treated cases. Methods: Thirty six elderly patients, aged ≥ 70, with the total of 39 aneurysms, were treated. The possibility of endovascular treatment was considered as the first option and surgical treatment as the second method of intervention. Results: No patient died and no patient became bedridden after the procedures. In surgical group (14 UIA), deterioration was observed in five cases at the time of discharge, but persisted in only two cases at follow-up. In endovascular group (25 UIA), deterioration was observed in one case at the time of discharge and persisted at follow-up. Endovascular techniques included coils placement alone in nine (36%) procedures, coiling with stent placement in five (20%) procedures and stent placement alone in eleven (44%) procedures. Follow-up DSA revealed no treatment effect in three patients after stent placement alone (12% of endovascularly treated aneurysms). Of these, two patients were successfully retreated with second flow-diverting stent placement and one patient refused retreatment. Conclusion: Treatment of elderly patients with UIA is relatively safe and effective. Worse short-term and long-term outcomes were observed among the operated compared to embolized patients. In patients treated with stent placement alone, treatment failure and the need for the next stage of embolization in some cases should be taken into account.
{"title":"Unruptured Intracranial Aneurysms in Elderly Patients: Results of Surgical and Endovascular Treatment","authors":"T. Czernicki, P. Kunert, A. Nowak, J. Żyłkowski, M. Jaworski, A. Marchel","doi":"10.6890/IJGE.202011_14(4).0011","DOIUrl":"https://doi.org/10.6890/IJGE.202011_14(4).0011","url":null,"abstract":"Background: Management of unruptured intracranial aneurysms (UIA) in elderly patients is controversial, taking into consideration their limited life-expectancy and existing comorbidities. With advances in endovascular techniques, we decided to evaluate treatment results in this population and to assess results in surgically and endovascularly treated cases. Methods: Thirty six elderly patients, aged ≥ 70, with the total of 39 aneurysms, were treated. The possibility of endovascular treatment was considered as the first option and surgical treatment as the second method of intervention. Results: No patient died and no patient became bedridden after the procedures. In surgical group (14 UIA), deterioration was observed in five cases at the time of discharge, but persisted in only two cases at follow-up. In endovascular group (25 UIA), deterioration was observed in one case at the time of discharge and persisted at follow-up. Endovascular techniques included coils placement alone in nine (36%) procedures, coiling with stent placement in five (20%) procedures and stent placement alone in eleven (44%) procedures. Follow-up DSA revealed no treatment effect in three patients after stent placement alone (12% of endovascularly treated aneurysms). Of these, two patients were successfully retreated with second flow-diverting stent placement and one patient refused retreatment. Conclusion: Treatment of elderly patients with UIA is relatively safe and effective. Worse short-term and long-term outcomes were observed among the operated compared to embolized patients. In patients treated with stent placement alone, treatment failure and the need for the next stage of embolization in some cases should be taken into account.","PeriodicalId":50321,"journal":{"name":"International Journal of Gerontology","volume":"235 1","pages":"310-314"},"PeriodicalIF":0.3,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85207211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-11-01DOI: 10.6890/IJGE.202011_14(4).0014
Qing Wu, B. Ye, X. Lv, Genxiang Mao, Sanying Wang, Zhuomei Chen, Guo-Fu Wang
Background: Many studies have demonstrated the beneficial effects of the mixed forest environment on human health. However, few studied the effect of the single tree species forest on human health. This study was explored the effect of C. camphora forest environment on elderly patients with hypertension (HTN). Methods: 31 elderly patients with essential HTN were randomly divided into two groups. Blood pressure (BP), pulse oxygen saturation (SpO_2%), heart rate (HR), heart rate variability (HRV) and levels of plasma high-sensitivity C-reactive protein (hs-CRP), as well as profile of mood states (POMS) test, were measured. Environment factors of two experimental sites were monitored. Categorical variables and continuous data were analyzed by Chi-square and t-test, respectively. Results: After forest bathing, subjects in the forest group showed significantly lower levels of diastolic blood pressure (DBP), low frequency (LF), the ratio of low frequency and high frequency (LF/HF) and hs-CRP, and greatly higher levels of SpO_2% and high frequency (HF) than that of in control group. Furthermore, negative mood subscale scores of POMS were significantly lower following forest bathing, while the positive score was much higher. However, the main components of volatile organic compounds (VOCs) in the two experimental sites were obviously different. Conclusion: C. Camphora environment significantly decreased the DBP and inflammatory level, balanced the autonomic activity and improved the mood state of participates, which might be associated with the biological effectiveness of terpenes, implying that C. Camphora environment might be an adjunctive therapy for HTN patients.
{"title":"Adjunctive Therapeutic Effects of Cinnamomum Camphora Forest Environment on Elderly Patients with Hypertension","authors":"Qing Wu, B. Ye, X. Lv, Genxiang Mao, Sanying Wang, Zhuomei Chen, Guo-Fu Wang","doi":"10.6890/IJGE.202011_14(4).0014","DOIUrl":"https://doi.org/10.6890/IJGE.202011_14(4).0014","url":null,"abstract":"Background: Many studies have demonstrated the beneficial effects of the mixed forest environment on human health. However, few studied the effect of the single tree species forest on human health. This study was explored the effect of C. camphora forest environment on elderly patients with hypertension (HTN). Methods: 31 elderly patients with essential HTN were randomly divided into two groups. Blood pressure (BP), pulse oxygen saturation (SpO_2%), heart rate (HR), heart rate variability (HRV) and levels of plasma high-sensitivity C-reactive protein (hs-CRP), as well as profile of mood states (POMS) test, were measured. Environment factors of two experimental sites were monitored. Categorical variables and continuous data were analyzed by Chi-square and t-test, respectively. Results: After forest bathing, subjects in the forest group showed significantly lower levels of diastolic blood pressure (DBP), low frequency (LF), the ratio of low frequency and high frequency (LF/HF) and hs-CRP, and greatly higher levels of SpO_2% and high frequency (HF) than that of in control group. Furthermore, negative mood subscale scores of POMS were significantly lower following forest bathing, while the positive score was much higher. However, the main components of volatile organic compounds (VOCs) in the two experimental sites were obviously different. Conclusion: C. Camphora environment significantly decreased the DBP and inflammatory level, balanced the autonomic activity and improved the mood state of participates, which might be associated with the biological effectiveness of terpenes, implying that C. Camphora environment might be an adjunctive therapy for HTN patients.","PeriodicalId":50321,"journal":{"name":"International Journal of Gerontology","volume":"26 1","pages":"327-331"},"PeriodicalIF":0.3,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87150938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-11-01DOI: 10.6890/IJGE.202011_14(4).0009
H. Hayashi, Hiroki Fukuda, T. Hasegawa, Hiroyuki Takahama, M. Amaki, H. Kanzaki, M. Sakamoto, Mika Maeda, M. Sata, S. Ito, Yasuhiro Izumiya, M. Yoshiyama, M. Kitakaze
{"title":"Impact of comorbidity of chronic obstructive pulmonary disease on cardiovascular events and prognosis in patients with chronic heart failure: A single-center retrospective observational study","authors":"H. Hayashi, Hiroki Fukuda, T. Hasegawa, Hiroyuki Takahama, M. Amaki, H. Kanzaki, M. Sakamoto, Mika Maeda, M. Sata, S. Ito, Yasuhiro Izumiya, M. Yoshiyama, M. Kitakaze","doi":"10.6890/IJGE.202011_14(4).0009","DOIUrl":"https://doi.org/10.6890/IJGE.202011_14(4).0009","url":null,"abstract":"","PeriodicalId":50321,"journal":{"name":"International Journal of Gerontology","volume":"1 1","pages":"298-303"},"PeriodicalIF":0.3,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89622755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-11-01DOI: 10.6890/IJGE.202011_14(4).0001
Chih-Po Chang, Ching-Hui You, L. Y. Tseng, Yun‐Ju Cheng, H. Tseng
Worldwide attention has been drawn to the recent COVID-19 outbreak Many studies have shown that under the pandemic, elderlies, especially those with chronic diseases, are more vulnerable than youths Upon infection, older people tend to endure a higher hospitalization and mortality rate, and the mortality rate after acute hospitalization appears even higher for frail elderlies than non-frail ones Moreover, older COVID-19 patients can exhibit different, atypical clinical manifestations such as falls, delirium, general weakness, functional decline, and other geriatric syndromes indicating frailty Therefore, this review suggests that the most effective way to improve the prognosis of COVID-19 infection in the elderly is to avoid the occurrence of frailty
{"title":"COVID-19 in Older Adults: A Focus on Clinical Characteristics and Frail Status","authors":"Chih-Po Chang, Ching-Hui You, L. Y. Tseng, Yun‐Ju Cheng, H. Tseng","doi":"10.6890/IJGE.202011_14(4).0001","DOIUrl":"https://doi.org/10.6890/IJGE.202011_14(4).0001","url":null,"abstract":"Worldwide attention has been drawn to the recent COVID-19 outbreak Many studies have shown that under the pandemic, elderlies, especially those with chronic diseases, are more vulnerable than youths Upon infection, older people tend to endure a higher hospitalization and mortality rate, and the mortality rate after acute hospitalization appears even higher for frail elderlies than non-frail ones Moreover, older COVID-19 patients can exhibit different, atypical clinical manifestations such as falls, delirium, general weakness, functional decline, and other geriatric syndromes indicating frailty Therefore, this review suggests that the most effective way to improve the prognosis of COVID-19 infection in the elderly is to avoid the occurrence of frailty","PeriodicalId":50321,"journal":{"name":"International Journal of Gerontology","volume":"3 1","pages":"256-259"},"PeriodicalIF":0.3,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78853915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-11-01DOI: 10.6890/IJGE.202011_14(4).0012
Hui-Kung Yu, Shu Chuan Chen, Yu Chi Chen
{"title":"Influence of self-efficacy and perceived barriers on physical activity among patients with chronic kidney disease","authors":"Hui-Kung Yu, Shu Chuan Chen, Yu Chi Chen","doi":"10.6890/IJGE.202011_14(4).0012","DOIUrl":"https://doi.org/10.6890/IJGE.202011_14(4).0012","url":null,"abstract":"","PeriodicalId":50321,"journal":{"name":"International Journal of Gerontology","volume":"56 1","pages":"315-319"},"PeriodicalIF":0.3,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83946221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-11-01DOI: 10.6890/IJGE.202011_14(4).0002
YuJiao Sun, Jinyang Li, Ling Chen, Liye Shi, Shijie Zhao, W. Tian, Haiyan Zhang, G. Qi
Aims: To observe the associations of hemoglobin, albumin and cholesterol as potential malnutrition risk biomarkers with coronary artery disease in the elderly. Methods: Individuals who were aged 80 or older took annual medical examination were included, they were divided into two groups based on the median levels of hemoglobin, albumin or cholesterol respectively. The incidences of coronary artery disease between two groups were compared. The levels of hemoglobin, albumin or cholesterol were compared in coronary artery disease and non-coronary artery disease group respectively. The relationships between hemoglobin, albumin and cholesterol and coronary artery disease were assessed by univariate and multivariate logistic regression analysises. Results: 1007 individuals with ≥ 80 years old were enrolled. The incidences of coronary artery disease were significantly higher in the lower level of hemoglobin and cholesterol groups than the higher level of hemoglobin and cholesterol groups respectively (both p ＜ 0.05). The levels of hemoglobin and cholesterol were siginificantly lower in coronary artery disease than non-coronary artery disease group (both p ＜ 0.05). After adjusting for potential confounding factors, hemoglobin was only protective factor for coronary artery disease in people with ≥ 80 years old (p ＜ 0.05). Conclusions: The general elderly population with lower levels of hemoglobin and cholesterol had the higher incidence of coronary artery disease, but only hemoglobin was a significant protective factor for coronary artery disease.
{"title":"Hemoglobin, Albumin and Cholesterol as Potential Malnutrition Risk Biomarkers Associated with Coronary Artery Disease in Older People: A Cross-Sectional Analysis","authors":"YuJiao Sun, Jinyang Li, Ling Chen, Liye Shi, Shijie Zhao, W. Tian, Haiyan Zhang, G. Qi","doi":"10.6890/IJGE.202011_14(4).0002","DOIUrl":"https://doi.org/10.6890/IJGE.202011_14(4).0002","url":null,"abstract":"Aims: To observe the associations of hemoglobin, albumin and cholesterol as potential malnutrition risk biomarkers with coronary artery disease in the elderly. Methods: Individuals who were aged 80 or older took annual medical examination were included, they were divided into two groups based on the median levels of hemoglobin, albumin or cholesterol respectively. The incidences of coronary artery disease between two groups were compared. The levels of hemoglobin, albumin or cholesterol were compared in coronary artery disease and non-coronary artery disease group respectively. The relationships between hemoglobin, albumin and cholesterol and coronary artery disease were assessed by univariate and multivariate logistic regression analysises. Results: 1007 individuals with ≥ 80 years old were enrolled. The incidences of coronary artery disease were significantly higher in the lower level of hemoglobin and cholesterol groups than the higher level of hemoglobin and cholesterol groups respectively (both p ＜ 0.05). The levels of hemoglobin and cholesterol were siginificantly lower in coronary artery disease than non-coronary artery disease group (both p ＜ 0.05). After adjusting for potential confounding factors, hemoglobin was only protective factor for coronary artery disease in people with ≥ 80 years old (p ＜ 0.05). Conclusions: The general elderly population with lower levels of hemoglobin and cholesterol had the higher incidence of coronary artery disease, but only hemoglobin was a significant protective factor for coronary artery disease.","PeriodicalId":50321,"journal":{"name":"International Journal of Gerontology","volume":"44 1","pages":"260-264"},"PeriodicalIF":0.3,"publicationDate":"2020-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82706416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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