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Review of: "[Perspective] Hypochlorous Acid (HOCL): A Multifaceted and Promising Therapeutic Perspective Against Human Immunodeficiency Virus (HIV)" 评论"[透视]次氯酸(HOCL):抗击人类免疫缺陷病毒(HIV)的前景广阔的多元疗法"
Pub Date : 2024-05-21 DOI: 10.32388/94wp1r
Bhumi Shah
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引用次数: 0
The Applicability of Design Thinking in the Tourism Sector, Kwazulu-Natal, South Africa 设计思维在南非夸祖鲁-纳塔尔旅游部门的适用性
Pub Date : 2024-05-21 DOI: 10.32388/arjmsr
Zahir Sayed, Cecile N Gerwel Proches, Abdullah Kader, Simon Taylor
One of the most significant corporate trends nowadays is design thinking, which gives firms the ability to develop their strategic thinking capabilities in order to tackle difficult problems. The goals of design thinking are to transform enterprises, encourage imaginative abilities, pinpoint needs and opportunities, and provide fresh ideas and scenarios for the company. South Africa's economy can grow as much as is desired by including all of these aspects. Design thinking is a capability that may deliberately assist the South African tourism industry in attaining its aspirational goals of increasing visitor arrivals, accelerating job development, and unleashing entrepreneurial prospects across sub-sectors that are closely related to the tourism sector. Tourism industry stakeholders must be aware of the evolving consumer demands. Understanding whether design thinking might be applied to the tourism sector in KwaZulu-Natal, South Africa, and whether doing so may be effective and advantageous for this sector, was the study's primary objective. Purposive sampling was used in this study's qualitative research approach. Eleven members of the tourism industry participated in a design thinking workshop, a focus group, and interviews in August and September 2021. The main conclusions showed that design thinking would be an effective technique to support improvements and innovation in the tourism sector, as all participants confirmed and agreed. The study's findings have led to various factors that can help design thinking improve tourism industry business. It is recommended that though design thinking can boost business in the tourism industry, a number of contributing factors must be properly implemented.
设计思维是当今最重要的企业趋势之一,它使企业有能力发展其战略思维能力,以解决棘手的问题。设计思维的目标是改造企业,鼓励想象力,明确需求和机遇,为公司提供新的想法和方案。通过将所有这些方面纳入其中,南非的经济可以实现预期增长。设计思维是一种能力,它可以有意识地帮助南非旅游业实现其愿望目标,即增加游客数量、加快就业发展,以及释放与旅游业密切相关的各子行业的创业前景。旅游业的利益相关者必须了解不断变化的消费者需求。了解设计思维是否可以应用于南非夸祖鲁-纳塔尔省的旅游业,以及这样做是否会对该行业有效和有利,是本研究的首要目标。本研究的定性研究方法采用了目的取样法。旅游业的 11 名成员参加了 2021 年 8 月和 9 月举行的设计思维研讨会、焦点小组和访谈。主要结论表明,设计思维是支持旅游业改进和创新的有效技术,所有参与者都对此表示肯定和赞同。研究结果提出了有助于设计思维改进旅游业业务的各种因素。我们建议,尽管设计思维可以促进旅游业的业务发展,但必须正确实施一系列促进因素。
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引用次数: 0
Perceptions and Challenges of Online Group Work Among Emirati Female Undergraduates 阿联酋女大学生对在线小组工作的看法和挑战
Pub Date : 2024-05-21 DOI: 10.32388/g3ugsd
Reem AlDhaheri
This study investigates the experiences of female undergraduate students at a federal university in the UAE with online group work. Using a questionnaire, the attitudes and perceptions of 32 female Emirati students were analyzed. Results indicate a generally positive attitude towards online group projects, highlighting the development of skills such as time management, teamwork, and leadership. Despite these benefits, challenges such as low contribution and poor communication were noted. The study recommends the careful design of online group assignments to ensure meaningful participation. Further research is suggested to explore faculty perspectives and conflict management in online group settings.
本研究调查了阿联酋一所联邦大学的女大学生在网上小组工作方面的经验。通过问卷调查,分析了 32 名阿联酋女学生的态度和看法。结果表明,学生对在线小组项目普遍持积极态度,并强调了时间管理、团队合作和领导力等技能的培养。尽管有这些好处,但也指出了一些挑战,如贡献率低和沟通不畅。研究建议精心设计在线小组作业,以确保有意义的参与。建议开展进一步研究,探讨在线小组环境中教师的观点和冲突管理。
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引用次数: 0
The Relationships Between the Perception of Physical and Economic Risks Measured Within the Road Environment and Within the Digital Environment and the Relationships Between Risk Perceptions Measured in Separate Environments 在道路环境和数字环境中测量的物理和经济风险感知之间的关系,以及在不同环境中测量的风险感知之间的关系
Pub Date : 2024-05-21 DOI: 10.32388/cwrsys.2
Amotz Perlman
Risk perception may be measured in different, separate environments. For example, drivers and pedestrians assess the risks in the road environment and workers assess the risks in the workplace environment.The purpose of this study is to examine the relationships between the risks perceived in several different environments in order to examine whether separate environments – such as the workplace environment and the road environment – are perceived as distinct environments, and whether the knowledge gained by learning to assess risks in one environment can be transferred to a new one.This study found a relationship between measures of risk perception while driving and a while crossing a road. Another finding is that a relationship was observed between the perception of risks related to vaccines and those related to medication, and a relationship was also observed between measures of risk perception while browsing the Internet and while using social media.The relationships between the measures of risk perception while crossing a road and the measures of risk perception while hiking in nature or in the workplace are small, as are the relationships between health-related risks and stock market-related risks.These findings suggest that separate environments, such as the workplace environment and the natural environment, are perceived as distinct environments from the road environment, and that knowledge learned in one environment cannot be transferred and used when in the other environment.
风险感知可以在不同的独立环境中进行测量。例如,司机和行人评估道路环境中的风险,而工人则评估工作场所环境中的风险。本研究的目的是检查在几个不同环境中感知到的风险之间的关系,以研究不同的环境(如工作场所环境和道路环境)是否被视为不同的环境,以及在一个环境中学习评估风险所获得的知识是否可以转移到一个新的环境中。另一项发现是,对疫苗相关风险的感知与对药物相关风险的感知之间存在关系,浏览互联网时的风险感知与使用社交媒体时的风险感知之间也存在关系。这些研究结果表明,工作场所环境和自然环境等独立环境被视为与道路环境截然不同的环境,在一种环境中学到的知识无法在另一种环境中转移和使用。
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引用次数: 0
The Impact of Systemic Racism and Trauma on Individuals, Families, and Communities in Toni Morrison’s Novels “Beloved” and “The Bluest Eye” 托尼-莫里森的小说《亲爱的》和《最蓝的眼睛》中系统性种族主义和创伤对个人、家庭和社区的影响
Pub Date : 2024-05-20 DOI: 10.32388/u8l1el
Sahaya Babina Rose, R. Kavitha, Richard Mwale
This abstract provides an overview of a research paper that delves into the themes of systemic racism and trauma as depicted in Toni Morrison’s novels ‘Beloved’ and ‘The Bluest Eye’. The paper aims to explore how these societal issues impact individuals, families, and communities within the narratives. It outlines the analysis of characters’ experiences to understand the influence of historical injustices and societal pressures on their identities, relationships, and overall lives. Moreover, it highlights the themes of race, identity, memory, and community as central to understanding the enduring effects of trauma and the resilience displayed by the characters.
本摘要概述了一篇研究论文,该论文深入探讨了托尼-莫里森的小说《心爱的人》和《最蓝的眼睛》中描写的系统性种族主义和创伤主题。论文旨在探讨这些社会问题如何影响叙事中的个人、家庭和社区。论文概述了对人物经历的分析,以了解历史不公正和社会压力对人物身份、人际关系和整体生活的影响。此外,它还强调了种族、身份、记忆和社区等主题,这些主题是理解创伤的持久影响和人物所表现出的复原力的核心。
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引用次数: 0
Impact of integrating smartphones in the teaching and learning of Mathematics in Mberengwa district, Zimbabwe 津巴布韦 Mberengwa 地区将智能手机融入数学教学的影响
Pub Date : 2024-05-20 DOI: 10.32388/gts31s
Kudzaishe Ganyani, Stella Muchemwa
Worldwide, the utility of smartphones in the teaching and learning of Mathematics has been greatly recognized and taken advantage of. This is mainly because of the precisions this technology can bring in the classroom. This study investigated the impact of integrating smart phones in the teaching and learning of Mathematics at secondary schools in Chegato Cluster in Mberengwa district, Zimbabwe. It also examined strategies that can be used to enhance the use of smartphones in these schools. The study used a mixed method approach where both qualitative and quantitative data was gathered and was used to answer the formulated research questions. Ten parents, 10 Mathematics teachers, 4 school heads and 40 learners participated in the study. The study found that the introduction of the competence-based curriculum by the ministry of Education in Zimbabwe, which is in solidarity with Education 5.0 calls for the use of smart phones in the teaching and learning of Mathematics which ensures that several modern skills are being acquired by learners in Chegato secondary schools. Learners in Chegato Cluster benefit by using smartphones to store soft copies of various Mathematics textbooks which are often scarce in hard-copy form. Students also benefit from Mathematical applications that are installed in their smartphones. Teachers use smartphones as media in the classroom to enhance learner-understanding of the concepts. Again, in Chegato, the use of smartphones has exposed learners to various Mathematical technological skills that help in the learning of Mathematics and has the potential of improving the pass rate. School heads and teachers acknowledged that the availability of smartphones in the schools has greatly assisted “O” level Mathematics learners to accomplish their tasks.Strategies that can be used to enhance the use of smartphones in secondary schools include the use of individualised student passwords which are controlled and monitored by the school administrators to ensure that the activities of each learner on the Internet can be tracked and any attempts by students to visit undesirable sites are detected. Also, the use of software applications, such as Mikrotik Hotspot Blocker, can be used to block students from accessing unsavoury Internet sites. The study concluded that though challenges such as lack of technological resources and some educators’ negative attitudes towards the use of smart phones affect Chegato Cluster, most participants found it helpful to use smartphones in the classroom because the gadget expose learners to new and better ways of dealing with Mathematical concepts. The study finally calls for all the involved parties in the cluster and beyond to actively take up their responsibilities facilitating the use of smartphones for the benefits of the students.
在世界范围内,智能手机在数学教学中的作用已得到极大的认可和利用。这主要是因为这项技术可以为课堂带来精确性。本研究调查了津巴布韦姆贝伦瓜区切加托中学将智能手机融入数学教学的影响。研究还探讨了在这些学校加强使用智能手机的策略。研究采用了混合方法,收集了定性和定量数据,用于回答提出的研究问题。10 名家长、10 名数学教师、4 名校长和 40 名学生参与了研究。研究发现,津巴布韦教育部推出的能力本位课程与教育 5.0 相一致,要求在数学教学中使用智能手机,以确保切加托中学的学生掌握多项现代技能。通过使用智能手机存储各种数学教科书的软拷贝,Chegato 群组的学生可以从中受益。智能手机中安装的数学应用程序也让学生受益匪浅。教师在课堂上使用智能手机作为媒体,加深学生对概念的理解。同样,在切加托,智能手机的使用让学生接触到各种数学技术技能,有助于数学学习,并有可能提高及格率。校领导和教师都承认,智能手机在学校的使用极大地帮助了 "O "级数学学习者完成他们的任务。在中学加强智能手机使用的策略包括使用由学校管理人员控制和监控的个性化学生密码,以确保可以跟踪每个学生在互联网上的活动,并检测学生访问不良网站的任何企图。此外,还可以使用 Mikrotik 热点拦截器等应用软件来阻止学生访问不良网站。研究得出的结论是,虽然缺乏技术资源和一些教育工作者对使用智能手机的消极态度等挑战影响了切加托集群,但大多数参与者认为在课堂上使用智能手机很有帮助,因为这种小工具让学习者接触到了处理数学概念的更好的新方法。最后,这项研究呼吁集群内外的所有相关方积极承担起责任,促进智能手机的使用,为学生谋福利。
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引用次数: 0
Modified free energy generation using permanent Neodymium Magnet based on Bedini with Maxwell and Lorenz gauge conditions 利用基于贝迪尼与麦克斯韦和洛伦兹量规条件的永久钕磁铁产生修正自由能
Pub Date : 2024-05-20 DOI: 10.32388/os9v96
Sahar Rahim, Haseeb Ahmed, Sohail Ahmad
An efficient, reliable, and real-time electricity generator is proposed by keeping in view the constraints, related to the electricity generation cost, resource reservoirs, greenhouse gas emission, energy storage, and power demand for a pre-defined residential area. Paramount importance is given to the rotor's design; coupled with movable neodymium magnets to increase the harvester's life span and system's net revenue. For the amplification in the stator output, a cost-effective approach is adopted that is based on the parallel winding of the bifilar coil. Furthermore, the coefficient of performance factor for the Bedini's smart school girl circuit based electricity harvester is modified by aiding the concepts of radiant energy incorporated with the electromagnetic phenomenon. Moreover, the mathematical model is formulated by the Maxwell equations using the Lorenz gauge condition to capture free vacuum energy from the environment. For the investigation, analysis, and corroboration of the proposed design, results are reported after performing extensive numerical computations and a comprehensive comparison between the original and modified design is stated in detail.
考虑到发电成本、资源储备、温室气体排放、能源储存以及预定住宅区的电力需求等相关限制因素,我们提出了一种高效、可靠和实时的发电机。转子的设计至关重要,再加上可移动的钕磁铁,可以延长收割机的使用寿命,增加系统的净收入。为了放大定子输出,采用了一种基于双纤丝线圈并联绕组的经济有效的方法。此外,通过将辐射能概念与电磁现象相结合,对基于贝迪尼智能女学生电路的电力收集器的性能系数进行了修改。此外,数学模型是通过麦克斯韦方程,利用洛伦兹规条件来捕捉环境中的自由真空能。为了调查、分析和证实所提出的设计,在进行大量数值计算后报告了结果,并详细说明了原始设计和改进设计之间的综合比较。
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引用次数: 0
Evaluating the Antimicrobial Activity of Esomeprazole Magnesium Trihydrate on Antibiotic-Resistant Bacteria Using Efflux Pumps 利用外排泵评估埃索美拉唑镁三水合物对耐药细菌的抗菌活性
Pub Date : 2024-05-20 DOI: 10.32388/aq4wlb
Thualfakar Hayder Hasan Abusaiba
BACKGROUND: Antibiotic resistance mediated by efflux pumps is a serious public health threat. Esomeprazole magnesium trihydrate (EMT) is a proton pump inhibitor with reported antimicrobial activity, but its effects against efflux-mediated resistance are unknown.OBJECTIVE: To evaluate the antimicrobial activity of EMT alone and in combination with the efflux pump inhibitor reserpine against clinical isolates of _Pseudomonas aeruginosa, Acinetobacter baumannii_ and _Staphylococcus aureus_.METHODS: Minimum inhibitory concentration (MIC) assays were performed using the broth microdilution method on 15 non-duplicate clinical isolates and reference strains with/without EMT and reserpine.RESULTS: EMT demonstrated activity against all isolates, with MIC ranges of 4-32 μg/mL, 8-64 μg/mL and 2-16 μg/mL respectively. EMT MICs decreased 4-8-fold for 13/15 isolates when combined with reserpine, indicating EMT may inhibit efflux pumps. Similar reductions occurred for comparator antibiotics.CONCLUSIONS: This study provides the first evidence that EMT possesses intrinsic antimicrobial activity against these pathogens and may function as both an efflux pump substrate and inhibitor. EMT warrants further investigation as a potential adjuvant antibiotic for overcoming efflux-mediated resistance.
背景:由外排泵介导的抗生素耐药性是一种严重的公共卫生威胁。目的:评估 EMT 单独使用以及与外排泵抑制剂瑞瑟平联合使用对铜绿假单胞菌、鲍曼不动杆菌和金黄色葡萄球菌临床分离株的抗菌活性。方法:采用肉汤微稀释法对 15 个不重复的临床分离株和参考菌株进行了最低抑菌浓度(MIC)测定,结果表明:EMT 对所有分离株都有活性,MIC 范围分别为 4-32μg/mL、8-64 μg/mL 和 2-16μg/mL。当 EMT 与利血平合用时,13/15 株分离物的 EMT MIC 下降了 4-8 倍,这表明 EMT 可能抑制了外排泵。对比抗生素也有类似的降低:本研究首次证明了 EMT 对这些病原体具有内在抗菌活性,并可同时作为外排泵底物和抑制剂发挥作用。EMT 作为克服外排介导的耐药性的潜在辅助抗生素,值得进一步研究。
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引用次数: 0
Automatic Content Analysis Systems: Detecting Disinformation in Social Networks 自动内容分析系统:检测社交网络中的虚假信息
Pub Date : 2024-05-20 DOI: 10.32388/tyb6ze
Roman Romanchuk, Victoria Vysotska
In the 21st century, the rapid rise of disinformation and propaganda has become a significant global issue, undermining democratic processes and socio-political institutions. Disinformation, defined as intentionally false or misleading information, aims to manipulate public opinion and cause economic harm. This paper explores the use of computational linguistics and machine learning methods to detect disinformation. Techniques such as text preprocessing, feature extraction, and classification algorithms (e.g., SVM, naive Bayes) are adapted for identifying fake news. Recent studies demonstrate the effectiveness of these methods in social media and news platforms, highlighting the importance of advanced models like GPT-4 in improving detection accuracy and combating the spread of disinformation.
在 21 世纪,虚假信息和宣传的迅速崛起已成为一个重大的全球性问题,破坏了民主进程和社会政治体制。虚假信息被定义为故意虚假或误导性信息,旨在操纵公众舆论并造成经济损失。本文探讨了如何利用计算语言学和机器学习方法来检测虚假信息。文本预处理、特征提取和分类算法(如 SVM、天真贝叶斯)等技术适用于识别假新闻。最近的研究证明了这些方法在社交媒体和新闻平台中的有效性,突出了 GPT-4 等先进模型在提高检测准确性和打击虚假信息传播方面的重要性。
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引用次数: 0
Last Days of Linearity in Business Analytics: Useful Analysis Based on Programming Tools 商业分析中线性的末日:基于编程工具的实用分析
Pub Date : 2024-05-20 DOI: 10.32388/q71143
Ihor Hurnyak, Hurniak Yaroslav
Modern tools, especially in the conditions of availability of computer calculations, no longer need simplification in the form of linearity in modeling business processes. Using the example of the interaction of strategies, Fama - French analysis, neural networks and other tools, the appropriateness of transforming the methodology in the direction of nonlinearity is shown. The method of simulating physical forces in economic processes is included in this analysis. A range of Python and R packages are used.
现代工具,特别是在计算机计算可用的条件下,不再需要以线性形式简化业务流程建模。以战略互动、法玛-弗伦奇分析、神经网络和其他工具为例,说明了向非线性方向转变方法的适当性。模拟经济过程中物理力量的方法也包含在这一分析中。使用了一系列 Python 和 R 软件包。
{"title":"Last Days of Linearity in Business Analytics: Useful Analysis Based on Programming Tools","authors":"Ihor Hurnyak, Hurniak Yaroslav","doi":"10.32388/q71143","DOIUrl":"https://doi.org/10.32388/q71143","url":null,"abstract":"Modern tools, especially in the conditions of availability of computer calculations, no longer need simplification in the form of linearity in modeling business processes. Using the example of the interaction of strategies, Fama - French analysis, neural networks and other tools, the appropriateness of transforming the methodology in the direction of nonlinearity is shown. The method of simulating physical forces in economic processes is included in this analysis. A range of Python and R packages are used.\u0000","PeriodicalId":503632,"journal":{"name":"Qeios","volume":"22 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141120639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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