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Modeling the epidemiologic individual. 流行病学个体建模。
IF 0.5 2区 历史学 Q2 HISTORY & PHILOSOPHY OF SCIENCE Pub Date : 2025-06-06 DOI: 10.1177/09526951251337680
Christopher J Phillips

Modern epidemiological methods often elide the distinction between individuals and populations in practice. Health data and outcomes gathered from a population can be, and often are, applied to a specific person, guiding preventive, diagnostic, and therapeutic interventions. This article looks at a key site for the origin of this elision, the Framingham Heart Study, and shows how a novel methodological 'calculator' for individual risk of future disease emerged from what was originally designed as a community-based epidemiological study. The article explains how the methodological transformation of epidemiology and biostatistics was surprisingly driven by methods emerging from outside of traditionally trained epidemiologists, particularly through statisticians trained in non-medical areas of the human sciences, including economics, sociology, and demography. It therefore also explains how and why epidemiologists became far more statistically sophisticated and the field more dependent on statistical methods by the 1970s than they had been in the 1940s.

现代流行病学方法在实践中往往忽略了个体和群体之间的区别。从人群中收集的健康数据和结果可以(而且经常)应用于特定的人,指导预防、诊断和治疗干预。这篇文章着眼于这一省略起源的关键地点,弗雷明汉心脏研究,并展示了一个新的方法“计算器”如何从最初设计为社区流行病学研究的个人未来疾病风险中出现。这篇文章解释了流行病学和生物统计学的方法转变是如何出人意料地受到传统训练的流行病学家之外的方法的推动,特别是通过在人文科学的非医学领域(包括经济学、社会学和人口学)受过训练的统计学家。因此,它也解释了为什么流行病学家在20世纪70年代比20世纪40年代在统计上变得更加复杂,并且该领域更加依赖统计方法。
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引用次数: 0
Being captured by queer kinship: Margaret Lowenfeld and Margaret Mead. 被奇怪的亲属关系俘获:玛格丽特·洛温菲尔德和玛格丽特·米德。
IF 0.5 2区 历史学 Q2 HISTORY & PHILOSOPHY OF SCIENCE Pub Date : 2025-04-10 eCollection Date: 2025-07-01 DOI: 10.1177/09526951251328114
Katherine A Hubbard

Margaret Lowenfeld (1890-1973) and Margaret Mead (1901-78) met in 1948. This eventful first meeting in London was the start of a fascinating working friendship, albeit a somewhat uneven one. The two women share particular similarities across their careers, including their positions as women in their respective fields of psychology and anthropology, though Mead was notably more renowned. They also both had substantial and long-lasting relationships with other women. In this article, I draw primarily upon archival resources of interviews with both Mead and Rhoda Métraux conducted about Lowenfeld following her death. In doing so I argue how such material not only reveals the type of relationship between Lowenfeld and Mead, but also raises questions about how lesbian relationships are historically understood. In recognising the queer worlds of these women, it is possible to extend historical thinking about the lesbian relationships they had. Crucially, it also demonstrates what a lesbian feminist historical approach uniquely provides. In addition to this, by likewise recognising myself as a queer feminist, it is possible to reveal the reflexive and emotional queer kinship which extends between historian and subject.

玛格丽特·洛温菲尔德(1890-1973)和玛格丽特·米德(1901-78)于1948年相识。在伦敦举行的第一次多事的会面,是一段令人着迷的工作友谊的开始,尽管这种友谊有些不平衡。这两位女性在她们的职业生涯中有着特别的相似之处,包括她们在各自的心理学和人类学领域中作为女性的地位,尽管米德的名气要大得多。他们也都与其他女性有着稳固而持久的关系。在这篇文章中,我主要利用了米德和罗达·姆萨特罗在洛温菲尔德去世后对她进行的采访的档案资源。在这样做的过程中,我认为这些材料不仅揭示了洛温菲尔德和米德之间的关系类型,而且还提出了关于历史上如何理解女同性恋关系的问题。认识到这些女性的酷儿世界,就有可能扩展对她们所拥有的女同性恋关系的历史思考。至关重要的是,它还展示了女同性恋女权主义历史研究的独特之处。除此之外,通过同样地承认自己是一个酷儿女权主义者,有可能揭示历史学家和主体之间的反身性和情感上的酷儿亲属关系。
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引用次数: 0
That men should put an enemy in their mouths to steal away their brains: Reconsidering the origins of model psychosis. 人类应该把敌人放进嘴里,偷走他们的大脑:重新思考模式精神病的起源。
IF 0.8 2区 历史学 Q2 HISTORY & PHILOSOPHY OF SCIENCE Pub Date : 2025-02-01 Epub Date: 2024-11-12 DOI: 10.1177/09526951241286744
Matthew Perkins-McVey

The promises of the Prozac century have fallen short; the number of novel, therapeutically significant medications successfully completing development shrinks every year; and the demand for better treatments constantly grows. Answering these hardships is a renewed optimism concerning the efficacy of controlled psychedelic therapy, a renaissance that has seen the resurgence of a familiar concept: intoxication as model psychosis. And yet, little has been made of where this peculiar idea originates. Why did we come to liken psychosis to intoxication, and why is this an idea we find so hard to shake? Questioning the conventional narrative that identifies the concept as emerging in the mid 19th century, this article seeks to uncover the conceptual foundations underlying what is now intended by 'model psychosis'. This investigation begins with an assessment of both Moreau de Tours's concept of hashish madness in 1845 and Emil Kraepelin's study of artificial insanity in the 1880s-90s. In seeking to contextualize these ideas, this article further considers the deeper historical association between intoxication and psychosis, instead proposing that intoxication represents an originary conception of madness. Bringing this examination into the 19th century, it becomes apparent that perceptions of intoxicants, and intoxication, were immanently participatory in the emerging understanding of psychosis. The contemporary understanding of model psychosis comes into focus when these elements coalesce with the advent of psychological modelling. Ultimately, the goal is not merely to understand how and why model psychosis became thinkable, but to examine how overlooked concepts have engendered new ways of being neuro-psychiatric subjects.

百忧解世纪的承诺落空了;成功完成研发的具有重要治疗意义的新型药物数量每年都在减少;对更好治疗方法的需求也在不断增长。对这些困难的回答是对受控迷幻疗法疗效的一种新的乐观主义,这种复兴已经看到了一个熟悉的概念的复苏:作为精神病模型的中毒。然而,很少有人知道这个奇特的想法是从哪里来的。为什么我们会把精神病比作醉酒,为什么我们发现这个想法很难动摇?对19世纪中期出现的概念的传统叙述提出质疑,本文试图揭示“模式精神病”的概念基础。本研究首先评估了1845年莫罗·德·图尔的大麻疯癫概念,以及19世纪80年代至90年代埃米尔·克雷佩林对人工精神错乱的研究。在试图将这些观点置于背景中,本文进一步考虑了醉酒和精神病之间更深层次的历史联系,而不是提出醉酒代表了疯狂的原始概念。将这一研究带入19世纪,很明显,对麻醉剂和中毒的感知,内在地参与了对精神病的新兴理解。当这些因素与心理模型的出现结合在一起时,对模型精神病的当代理解就成为焦点。最终,我们的目标不仅仅是理解模型精神病是如何以及为什么变得可以想象的,而是要研究被忽视的概念是如何产生神经精神病学学科的新方法的。
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引用次数: 0
The model multiple: Representing cancer in sub-Saharan Africa. 模型倍数:代表撒哈拉以南非洲的癌症。
IF 0.8 2区 历史学 Q2 HISTORY & PHILOSOPHY OF SCIENCE Pub Date : 2024-12-10 DOI: 10.1177/09526951241286733
Jennifer Fraser, David Reubi, Thandeka Cochrane

Over the past half-century, modelling has come to play an increasingly important role in cancer research. These representational tools frame perceptions of malignant disease, guide public health responses, and help determine which interventions are necessary. But what makes a cancer model a model? What authority do they have? What stories do they tell? And how do they shape our understanding of disease and bodies? To shed light on these questions, this article explores the long history of cancer modelling in sub-Saharan Africa: a place where malignant disease has often been imagined as different, and where experimentation and improvisation in cancer research and treatment has been rife. Drawing on archival and ethnographic sources, we examine modelling strategies that health professionals have used to generate information about cancer in Africa from the mid 20th century to the present day. Focusing on three different case studies - anatomical models of Burkitt's lymphoma patients, diagnostic models for Kaposi sarcoma, and statistical models of the African smoking and lung cancer epidemic - we meditate on the multiplicity of models and modelling by identifying the epistemic strands that hold these representations together, as well as what sets them apart. In addition to contributing to discussions of how cancer research has taken shape beyond the Anglo-American realm, our article helps expand and complicate our understandings of what a disease model is.

在过去的半个世纪里,模型在癌症研究中扮演着越来越重要的角色。这些代表性工具构成了对恶性疾病的认识,指导公共卫生反应,并帮助确定哪些干预措施是必要的。但是是什么让一个癌症模型成为一个模型呢?他们有什么权力?他们讲了什么故事?它们又如何影响我们对疾病和身体的理解?为了阐明这些问题,本文探讨了撒哈拉以南非洲地区癌症建模的悠久历史:在那里,恶性疾病经常被认为是不同的,在那里,癌症研究和治疗的实验和即兴创作一直很普遍。利用档案和人种学资料,我们研究了从20世纪中期到现在,卫生专业人员用来生成非洲癌症信息的建模策略。关注三个不同的案例研究——伯基特淋巴瘤患者的解剖模型、卡波西肉瘤的诊断模型以及非洲吸烟和肺癌流行的统计模型——我们通过识别将这些表征结合在一起的认知链,以及将它们区分开来的知识链,来思考模型和建模的多样性。除了讨论癌症研究是如何在英美之外形成的,我们的文章还有助于扩展和复杂化我们对疾病模型的理解。
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引用次数: 0
In the shadow of the tree: The diagrammatics of relatedness in genealogy, anthropology, and genetics as epistemic, cultural, and political practice 树影中:家谱学、人类学和遗传学中的亲缘关系图解作为认识论、文化和政治实践
IF 0.9 2区 历史学 Q2 HISTORY & PHILOSOPHY OF SCIENCE Pub Date : 2024-07-21 DOI: 10.1177/09526951241261837
Marianne Sommer, Caroline Arni, Staffan Müller-Wille, Simon Teuscher
The preferred tool for conceptualizing, determining, and claiming relations of kinship, ancestry, and descent among humans are diagrams. For this reason, and at the same time to avoid a reduction to biology as transported by terms such as kinship, ancestry, and descent, we introduce the expression diagrammatics of relatedness. We seek to understand the enormous influence that especially tree diagrams have had as a way to express and engage with human relatedness, but hold that this success can only be adequately understood by attending to what in fact are broader diagrammatic practices. These practices bring to light that diagrams of relatedness do not simply make visible natural connections, but create or deny relations in particular ways and for particular reasons. In this special section, contributors investigate diagrams of relatedness in genealogy, heredity, as well as biological and social anthropology. Conceiving of diagrams as techniques that transcend such binaries as ‘thought and action’ and ‘image and text’, we aim at an understanding of how they were constructed and how they functioned in particular epistemic, cultural, and political contexts.
将人类之间的亲属关系、祖先关系和世系关系概念化、确定和主张的首选工具是图表。为此,同时为了避免将亲缘关系、祖先和血统等术语简化为生物学,我们引入了亲缘关系图解这一表达方式。我们试图理解特别是树图作为表达和处理人类亲缘关系的一种方式所产生的巨大影响,但认为只有关注实际上是更广泛的图解实践,才能充分理解这种成功。这些实践揭示了关联性图解并不只是简单地显示自然联系,而是以特定的方式和出于特定的原因创造或否认关系。在本专栏中,撰稿人研究了家谱学、遗传学以及生物和社会人类学中的亲缘关系图解。我们将图解视为超越 "思想与行动"、"图像与文本 "等二元对立的技术,旨在了解它们是如何构建的,以及它们在特定的认识论、文化和政治背景下是如何发挥作用的。
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引用次数: 0
Low on the Kinsey scale: Homosexuality in Swedish and Finnish sex research, 1960s–1990s 金赛量表上的低分:瑞典和芬兰性研究中的同性恋,1960-1990 年代
IF 0.9 2区 历史学 Q2 HISTORY & PHILOSOPHY OF SCIENCE Pub Date : 2024-05-06 DOI: 10.1177/09526951241245040
Riikka Taavetti
This article addresses the history of sociological sex research and its reception in Sweden and Finland. It describes the background and implementation of the first study in Sweden in 1967, and how the methodology of this study was adopted in Finland in 1971. Both of these studies were followed up in the 1990s with surveys that documented the changes in sexuality, 1992 in Finland and 1996 in Sweden. As the studies were labelled ‘Kinsey studies’ of their respective countries, the article examines the effect that the work of Alfred Kinsey's research group had on them. In particular, the article pays attention to the role of homosexuality in the studies and their reception, both in the mainstream media and in lesbian and gay organizations’ magazines. The article argues that, even though the studies recognized their position on the continuum of sex research stemming from Kinsey's work, they did not have a similar role in normalizing homosexuality. On the contrary, the studies showed diminishingly small numbers of homosexual respondents, even in the 1990s, when lesbian and gay rights were rapidly developing, and the studies were used to argue against equality and minority rights.
本文介绍了性社会学研究的历史及其在瑞典和芬兰的接受情况。文章介绍了 1967 年在瑞典开展的第一项研究的背景和实施情况,以及芬兰是如何在 1971 年采用这项研究的方法的。在 20 世纪 90 年代,这两项研究又分别于 1992 年和 1996 年在芬兰和瑞典进行了调查,记录了性行为的变化。由于这两项研究在各自国家被称为 "金赛研究",因此文章探讨了阿尔弗雷德-金赛研究小组的工作对这两项研究的影响。文章特别关注了同性恋在这些研究中的作用,以及主流媒体和女同性恋组织杂志对这些研究的反应。文章认为,尽管这些研究承认了自己在源自金赛工作的性研究连续体中的地位,但它们在使同性恋正常化方面并没有发挥类似的作用。相反,这些研究显示,即使在女同性恋和男同性恋权利迅速发展的 20 世纪 90 年代,同性恋受访者的人数也越来越少,这些研究被用来反对平等和少数人权利。
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引用次数: 0
The origins of film, psychology and the neurosciences 电影、心理学和神经科学的起源
IF 0.9 2区 历史学 Q2 HISTORY & PHILOSOPHY OF SCIENCE Pub Date : 2024-04-29 DOI: 10.1177/09526951241244979
Bonnie Evans
The invention of film technologies in France at the end of the 19th century inspired neurologists and associated professionals to engage with this new medium to demonstrate their theories of the brain, the nervous system, and the mind. Beginning with the origins of cinema in Paris, this article explores how film technologies were used at La Salpêtrière, and beyond, to visualise internal mental processes, and to support the burgeoning sciences of the mind. This film-making became increasingly sophisticated by the late 1910s and early 1920s, creating innovative ways to present psychological experiences on film. This article focuses on films produced by Albert Londe, Vincenzo Neri, Gheorghe Marinescu, and Jean Comandon. It argues that these polymaths created new filming techniques that built complexity into the visual articulation of psychological concepts. Their films were essential to shaping early debates in neurology, psychology, and the observational sciences during this critical period in the establishment of the modern sciences of the self.
19 世纪末,法国发明了电影技术,这激发了神经学家和相关专业人士利用这种新媒体来展示他们的大脑、神经系统和思维理论。本文从电影在巴黎的起源开始,探讨电影技术如何在 Salpêtrière 及其他地方被用于将内部心理过程可视化,并为新兴的心智科学提供支持。到 20 世纪 10 年代末和 20 世纪 20 年代初,电影制作变得越来越复杂,创造出了在电影中呈现心理体验的创新方式。本文重点介绍阿尔伯特-隆德(Albert Londe)、文森佐-内里(Vincenzo Neri)、格奥尔基-马里内斯库(Gheorghe Marinescu)和让-科曼东(Jean Comandon)制作的电影。文章认为,这些多面手创造了新的拍摄技术,将复杂性融入到心理概念的视觉表达中。在建立现代自我科学的关键时期,他们的电影对影响神经学、心理学和观察科学的早期辩论至关重要。
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引用次数: 0
Finding modernity in England's past: Social anthropology and the remaking of social history in Britain, 1959–77* 在英国的过去中寻找现代性:社会人类学与英国社会史的重塑,1959-77 年*。
IF 0.9 2区 历史学 Q2 HISTORY & PHILOSOPHY OF SCIENCE Pub Date : 2024-04-27 DOI: 10.1177/09526951241242327
Freddy Foks
British historians drew on anthropological exemplars to remake social history between 1959 and 1977. Eric Hobsbawm's ‘primitive rebels’, Peter Laslett's World We Have Lost, Keith Thomas’s studies of witchcraft, and E. P. Thompson's ‘moral economy’ were all inspired by contemporary social anthropology, and they transformed historians’ understanding of the past. Reconstructing this moment of cross-disciplinary research contributes to our understanding of broader changes in the mid-century human sciences. This was a moment of grand theorizing about ‘modernization’, capitalism, and industrialization. Social historians responded to these concerns by drawing analogies between the past and the ethnographic present. The result was a number of hugely influential studies of social change that posed new questions to those seeking to create abstract models of modernization out of the English past.
1959 年至 1977 年间,英国历史学家借鉴人类学典范重塑社会史。埃里克-霍布斯鲍姆(Eric Hobsbawm)的 "原始叛逆者"、彼得-拉斯莱特(Peter Laslett)的《我们失去的世界》、基思-托马斯(Keith Thomas)的巫术研究以及 E. P. 汤普森(E. P. Thompson)的 "道德经济 "都受到了当代社会人类学的启发,它们改变了历史学家对过去的理解。重建这一跨学科研究的时刻有助于我们了解世纪中期人文科学的广泛变化。这是一个关于 "现代化"、资本主义和工业化的宏大理论的时代。社会史学家通过类比过去和人种学的现在来回应这些关切。由此产生了许多极具影响力的社会变迁研究,这些研究向那些试图从英国的过去中创造出抽象的现代化模式的人提出了新的问题。
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引用次数: 0
Mother-blaming revisited: Gender, cinematography, and infant research in the heyday of psychoanalysis. 重新审视母亲的指责:精神分析鼎盛时期的性别、电影摄影和婴儿研究
IF 0.9 2区 历史学 Q2 HISTORY & PHILOSOPHY OF SCIENCE Pub Date : 2024-04-01 Epub Date: 2023-07-25 DOI: 10.1177/09526951231187556
Felix E Rietmann

This article examines cinematographic observational studies of infants conducted by a loosely connected group of female psychologists and physicians in the USA from the 1930s to the 1960s. Largely forgotten today, these practitioners realized detailed and carefully planned research projects about infant behavior in a variety of settings-from the laboratory to the well-baby clinic. Although their studies were in conversation with better-known works, such as John Bowlby's research on attachment and René Spitz's films on institutionalized infants, they differed in a close examination of individual characteristics of babies and a critical attitude toward contemporary notions of 'pathological mothering'. In closely following the work of several researchers, including but not limited to pediatrician Margaret Fries (1898-1987), the clinical psychologist Sibylle Escalona (1915-96) and her team members-child psychiatrist Mary Leitch (1914-?) and avant-garde photographer Ellen Auerbach (1906-2004)-and psychologist Anneliese Korner (1918-2010), I argue that their cinematographic works shed a more nuanced light on the landscape of infant research and child psychiatry in the mid 20th century, and open a way for alternative readings of gender, psychoanalysis, and scientific observation at that time.

这篇文章考察了20世纪30年代到60年代美国一群松散联系的女性心理学家和医生对婴儿进行的电影观察研究。这些实践者在今天基本上被遗忘了,他们实现了在各种环境下——从实验室到健康婴儿诊所——对婴儿行为进行详细而精心策划的研究项目。尽管他们的研究与约翰·鲍尔比关于依恋的研究和雷诺·斯皮茨关于制度化婴儿的电影等更知名的作品有联系,但他们在对婴儿个体特征的仔细研究和对当代“病态育儿”概念的批判态度上有所不同。在密切关注几位研究人员的工作后,包括但不限于儿科医生玛格丽特·弗里斯(1898-1987),临床心理学家西比勒·埃斯卡罗纳(1915 - 1996)和她的团队成员——儿童精神病学家玛丽·莱奇(1914 - ?)和前卫摄影师埃伦·奥尔巴赫(1906-2004)——心理学家安内利斯·科尔纳(1918-2010),我认为他们的电影作品更细致地揭示了20世纪中期婴儿研究和儿童精神病学的景观。并为当时对性别、精神分析和科学观察的另类解读开辟了一条道路。
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引用次数: 0
The visualization of autism: Filming children at the Maudsley Hospital, London, 1957–8 自闭症的可视化:拍摄伦敦莫兹利医院的儿童,1957-2008 年
IF 0.9 2区 历史学 Q2 HISTORY & PHILOSOPHY OF SCIENCE Pub Date : 2024-04-01 DOI: 10.1177/09526951241238650
Janet Harbord
This article examines three films made during the 1950s by Elwyn James Anthony at the psychotic clinic for children at the Maudsley Hospital that marked an important transition in the purpose and practice of visual documentation in a clinical setting: film as a research tool was transitioning from the recording of external signs as indicators of internal subjective states, to the capture of the visual flow of communication between subjects. It is a shift that had a particular impact on the emergent classification of autism, a modality not yet properly separated from the broader term of psychosis, as a non-relational condition whose visual capture demonstrated a void of inter-human communicational exchange. Film was significant not only as a recording apparatus, but as a method of cutting and crafting sequences of movements into brief repetitive motifs. The filmed behaviour of children remained opaque to interpretation, a ‘finding’ that facilitated the modelling of an emergent autism as subjects who were isolated, alienated and automaton-like, inhabiting a separate temporality. The article situates this ‘second’, affectless autism, within a broader context of post-war research into gestures as a language of the body, developed largely through an intellectual network of German émigré psychoanalysts who had fled to the US and UK in the 1930s.
本文研究了埃尔温-詹姆斯-安东尼(Elwyn James Anthony)于 20 世纪 50 年代在莫兹利医院(Maudsley Hospital)儿童精神病诊所拍摄的三部电影,这三部电影标志着临床环境中视觉记录的目的和实践的重要转变:电影作为一种研究工具,正在从记录作为内部主观状态指标的外部迹象,转变为捕捉受试者之间交流的视觉流。这一转变对自闭症的新分类产生了特别的影响,自闭症是一种尚未从更广泛的精神病术语中适当分离出来的模式,是一种非关系性疾病,其视觉捕捉显示了人与人之间沟通交流的缺失。电影的重要意义不仅在于它是一种记录工具,还在于它是一种将动作序列剪辑成简短重复主题的方法。被拍摄的儿童行为仍然无法解释,这一 "发现 "有助于将新出现的自闭症儿童塑造成孤立、疏离和自动的主体,他们居住在一个独立的时空中。文章将这种 "第二种"、无情感的自闭症置于战后研究手势作为身体语言的大背景下,这种研究主要是通过 20 世纪 30 年代逃往美国和英国的德国移民精神分析学家的知识网络发展起来的。
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引用次数: 0
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