Pub Date : 2024-05-20DOI: 10.58806/ijhmr.2024.v3i05n06
Wahyudi Wahyudi, Siti Nurhaliza Fardani, Vina Noura, Dyva Patricia Siahaan, Fifia El Zuhra, Azzahra Al Adawiyah
T2DM is a chronic disease characterized by high blood glucose levels due to insulin resistance or insufficient insulin production. Aim of this study was to analyze the direct medical costs of outpatient T2DM management with cardiovascular disease complications. 58 T2DM patients at the Universitas Sumatera Utara Hospital, in Sumatera Utara, Indonesia were recruited in this study in April-May 2023. This study analyze based on payer prespective named as Badan Penyelenggara Jaminan Sosial (BPJS). This quantitative research was carried out by collecting data retrospectively. Result of this study show that phycian service IDR 8,715,000, drug acquisition cost IDR 13,081,242, laboratory examination IDR 2,531,000, medical execution IDR 410,000, and administration IDR 1,425,000. Conclusion of this study, that drug acquisition cost was the highest cost IDR 13,081,242.
{"title":"Analysis Of Direct Medical Costs On Type 2 Diabetes Mellitus Outpatient With Cardiovascular Disease","authors":"Wahyudi Wahyudi, Siti Nurhaliza Fardani, Vina Noura, Dyva Patricia Siahaan, Fifia El Zuhra, Azzahra Al Adawiyah","doi":"10.58806/ijhmr.2024.v3i05n06","DOIUrl":"https://doi.org/10.58806/ijhmr.2024.v3i05n06","url":null,"abstract":"T2DM is a chronic disease characterized by high blood glucose levels due to insulin resistance or insufficient insulin production. Aim of this study was to analyze the direct medical costs of outpatient T2DM management with cardiovascular disease complications. 58 T2DM patients at the Universitas Sumatera Utara Hospital, in Sumatera Utara, Indonesia were recruited in this study in April-May 2023. This study analyze based on payer prespective named as Badan Penyelenggara Jaminan Sosial (BPJS). This quantitative research was carried out by collecting data retrospectively. Result of this study show that phycian service IDR 8,715,000, drug acquisition cost IDR 13,081,242, laboratory examination IDR 2,531,000, medical execution IDR 410,000, and administration IDR 1,425,000. Conclusion of this study, that drug acquisition cost was the highest cost IDR 13,081,242.","PeriodicalId":504355,"journal":{"name":"International Journal Of Health & Medical Research","volume":"42 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141119114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-20DOI: 10.58806/ijhmr.2024.v3i05n07
N. I. Abdul-Zahra, Zahraa K. Taiban
One of the most common ailments is hypertension, or high blood pressure. Many say this disease concerns them because it causes heart attack and stroke, which kill millions around the world each year. In recent years, the number of hypertension patients has been growing at an alarming rate. Humans with Hypertinsure about 1 billion The developing countries are particularly hard-hit What is more worrying than increasing numbers that have already skyrocketed--it's LMICC soaring These countries have also been especially hard hit by the burden of hypertension due to various socioeconomic aspects including income, wealth, employment status and place of residence. [1] Hypertension with its 41.5 incidence rate for every 1000 people is a big concern in Iraq. It is no different for children, obesity, poor dietary choices and lack of physical activity are all also associated with increasing risk of hypertension. Their experience makes clear how important it is to get hypertension under control and take measures prematurely.
{"title":"Association Between High Blood Pressure And Cardiovascular Disease In Iraq: A Review","authors":"N. I. Abdul-Zahra, Zahraa K. Taiban","doi":"10.58806/ijhmr.2024.v3i05n07","DOIUrl":"https://doi.org/10.58806/ijhmr.2024.v3i05n07","url":null,"abstract":"One of the most common ailments is hypertension, or high blood pressure. Many say this disease concerns them because it causes heart attack and stroke, which kill millions around the world each year. In recent years, the number of hypertension patients has been growing at an alarming rate. Humans with Hypertinsure about 1 billion The developing countries are particularly hard-hit What is more worrying than increasing numbers that have already skyrocketed--it's LMICC soaring These countries have also been especially hard hit by the burden of hypertension due to various socioeconomic aspects including income, wealth, employment status and place of residence. [1] Hypertension with its 41.5 incidence rate for every 1000 people is a big concern in Iraq. It is no different for children, obesity, poor dietary choices and lack of physical activity are all also associated with increasing risk of hypertension. Their experience makes clear how important it is to get hypertension under control and take measures prematurely.","PeriodicalId":504355,"journal":{"name":"International Journal Of Health & Medical Research","volume":"17 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141119549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-16DOI: 10.58806/ijhmr.2024.v3i05n04
SALIM OMAMBIA
Objective: The project aimed to call to mind the exploration of health management and information systems among healthcare workers at Kenyatta National Hospital, Kenya. Design setting: The investigation deployed a cross-sectional study. Subjects or participants: A sample total of 263 respondents was calculated using the Krecie and Morgan formula for the quantitative study. A strict inclusion criterion was followed to select the respondents from all trained health personnel in Kenyatta National Hospital. The study utilized an interview schedule. Data were analyzed using SPSS version 21 while qualitative data was analyzed on themes developed. Data presentation was in the form of quantitative statistics such as frequency distribution, percentages and tables. Qualitative results were presented in verbatim form. Results: A total of 263 respondents were engaged in the quantitative study. The study utilized a questionnaire and a key informant interview guide. Before processing quantitative data, data was cleaned, coded and keyed into MS Excel database computer and analyzed using SPSS version 21. Descriptive statistics were used to describe measures of central tendency and dispersion. Findings were presented using frequency distributions and summary tables. Associations between predictor and outcome variables were run through Correlational statistics. Of the 263 respondents, 193 (72.6%) were optimistic that HMIS had brought about better up-dating and expertise in healthcare service delivery and 40(15%) were neutral while, 33(12.4%) were pessimistic about the concept. A weak positive correlation (r = 0.3345, p =0.03) between self-confidence in productivity and HMIS implementation was observed. Conclusion:The KNH management needs to ensure that there is system thinking, where each staff is not only motivated but also feels part and parcel of a robust and cohesive HIMS process
{"title":"Exploring Health Information And Management System Trends Among Healthcare Workers At Kenyatta National Hospital","authors":"SALIM OMAMBIA","doi":"10.58806/ijhmr.2024.v3i05n04","DOIUrl":"https://doi.org/10.58806/ijhmr.2024.v3i05n04","url":null,"abstract":"Objective: The project aimed to call to mind the exploration of health management and information systems among healthcare workers at Kenyatta National Hospital, Kenya. Design setting: The investigation deployed a cross-sectional study. Subjects or participants: A sample total of 263 respondents was calculated using the Krecie and Morgan formula for the quantitative study. A strict inclusion criterion was followed to select the respondents from all trained health personnel in Kenyatta National Hospital. The study utilized an interview schedule. Data were analyzed using SPSS version 21 while qualitative data was analyzed on themes developed. Data presentation was in the form of quantitative statistics such as frequency distribution, percentages and tables. Qualitative results were presented in verbatim form. Results: A total of 263 respondents were engaged in the quantitative study. The study utilized a questionnaire and a key informant interview guide. Before processing quantitative data, data was cleaned, coded and keyed into MS Excel database computer and analyzed using SPSS version 21. Descriptive statistics were used to describe measures of central tendency and dispersion. Findings were presented using frequency distributions and summary tables. Associations between predictor and outcome variables were run through Correlational statistics. Of the 263 respondents, 193 (72.6%) were optimistic that HMIS had brought about better up-dating and expertise in healthcare service delivery and 40(15%) were neutral while, 33(12.4%) were pessimistic about the concept. A weak positive correlation (r = 0.3345, p =0.03) between self-confidence in productivity and HMIS implementation was observed. Conclusion:The KNH management needs to ensure that there is system thinking, where each staff is not only motivated but also feels part and parcel of a robust and cohesive HIMS process","PeriodicalId":504355,"journal":{"name":"International Journal Of Health & Medical Research","volume":"38 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140971442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: There are several efforts to address impacted teeth, one of which is through a minor surgical intervention called Odontectomy. There are also several complications that may arise after Odontectomy is performed, but this usually only occurs for a few days, and patients will experience a more comfortable feeling compared to before the Odontectomy. This research aims to analyze the difference in the quality of life of patients before and after the Odontectomy surgical procedure. Material and Methods: The method employed in this research was analytical observational, using a Cross-Sectional design. The sampling technique used was Accidental sampling, which involved patients who underwent Odontectomy at Bhayangkara Hospital Semarang Indonesia in October 2023. The total sample size was 10 patients based on inclusion criteria. The research was conducted using the OHIP-14 (Oral Health Impact Profile 14) questionnaire, consisting of 14 questions from 7 dimensions. Data analysis was performed using the Wilcoxon test because the data scale was ordinal. Results: The results of this study indicated that before undergoing Odontectomy, the quality of life of patients at a moderate level was 3 individuals (30%), while those at a low level were 7 individuals (70%). After Odontectomy was performed, the quality of life of patients improved, with 1 individual (10%) at a moderate level, 9 individuals (90%) at a good level, and 1 individual (10%) at a very good level. The statistical analysis results showed that the significance value (P) was 0.005, indicating that p < 0.05. Conclusion: The conclusion that can be drawn from this research is that there was a significant difference in the quality of life of patients before and after undergoing the Odontectomy procedure.
{"title":"The Influence Of Minor Surgical Intervention On Quality Of Life In Third Molar Impaction Cases","authors":"Erwid Fatchur Rahman, Erdianto Setya Wardhana, Hayyu Failasufa","doi":"10.58806/ijhmr.2024.v3i05n03","DOIUrl":"https://doi.org/10.58806/ijhmr.2024.v3i05n03","url":null,"abstract":"Background: There are several efforts to address impacted teeth, one of which is through a minor surgical intervention called Odontectomy. There are also several complications that may arise after Odontectomy is performed, but this usually only occurs for a few days, and patients will experience a more comfortable feeling compared to before the Odontectomy. This research aims to analyze the difference in the quality of life of patients before and after the Odontectomy surgical procedure. Material and Methods: The method employed in this research was analytical observational, using a Cross-Sectional design. The sampling technique used was Accidental sampling, which involved patients who underwent Odontectomy at Bhayangkara Hospital Semarang Indonesia in October 2023. The total sample size was 10 patients based on inclusion criteria. The research was conducted using the OHIP-14 (Oral Health Impact Profile 14) questionnaire, consisting of 14 questions from 7 dimensions. Data analysis was performed using the Wilcoxon test because the data scale was ordinal. Results: The results of this study indicated that before undergoing Odontectomy, the quality of life of patients at a moderate level was 3 individuals (30%), while those at a low level were 7 individuals (70%). After Odontectomy was performed, the quality of life of patients improved, with 1 individual (10%) at a moderate level, 9 individuals (90%) at a good level, and 1 individual (10%) at a very good level. The statistical analysis results showed that the significance value (P) was 0.005, indicating that p < 0.05. Conclusion: The conclusion that can be drawn from this research is that there was a significant difference in the quality of life of patients before and after undergoing the Odontectomy procedure.","PeriodicalId":504355,"journal":{"name":"International Journal Of Health & Medical Research","volume":"2 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140968799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-15DOI: 10.58806/ijhmr.2024.v3i05n02
Ozdan Akram Ghareeb, Goljameen Midhat Abdulla, Awni Ismail Sultan
There is an urgent need for new supportive treatment options against infectious viral diseases, given the rapid spread and huge number of individuals affected worldwide by these diseases, so cost-effective, globally available and safe options with minimal side effects and simple application are highly assured. This study will therefore discuss the potential of vitamin D supplementation as a preventive and therapeutic agent in combination with other strategies, as this vitamin meets all the criteria described above. A variety of data are available on the association of vitamin D with respiratory infections and viral infections, as well as on the immune response by supplementation with this vitamin.Vitamin D deficiency adds to the variables that make people more susceptible to infection and the damaging development of COVID-19, as there is a correlation between its levels in the body and the severity of COVID-19 infections. Due to its direct antiviral and anti-inflammatory properties, it can be assumed that maintaining it within normal levels in the body is necessary to maintain the health of the body, and when its level in the body is below the optimal level, this can be compensated for with vitamin D supplements.
鉴于传染性病毒性疾病在全球范围内传播迅速，患病人数众多，因此迫切需要新的辅助治疗方案来应对这些疾病，因此，成本效益高、全球通用、安全、副作用小且应用简单的方案就显得尤为重要。因此，本研究将讨论维生素 D 补充剂作为预防和治疗药物与其他策略相结合的潜力，因为维生素 D 符合上述所有标准。关于维生素 D 与呼吸道感染和病毒感染的关系，以及补充这种维生素后的免疫反应，目前已有多种数据。维生素 D 的缺乏增加了人们更容易受到感染和 COVID-19 破坏性发展的变数，因为维生素 D 在体内的水平与 COVID-19 感染的严重程度存在相关性。由于维生素 D 具有直接抗病毒和抗炎的特性，因此可以认为，将其维持在体内正常水平是保持身体健康的必要条件，当其在体内的水平低于最佳水平时，可以通过补充维生素 D 来弥补。
{"title":"Vitamin D Deficiency And Risk Of COVID-19 Infection","authors":"Ozdan Akram Ghareeb, Goljameen Midhat Abdulla, Awni Ismail Sultan","doi":"10.58806/ijhmr.2024.v3i05n02","DOIUrl":"https://doi.org/10.58806/ijhmr.2024.v3i05n02","url":null,"abstract":"There is an urgent need for new supportive treatment options against infectious viral diseases, given the rapid spread and huge number of individuals affected worldwide by these diseases, so cost-effective, globally available and safe options with minimal side effects and simple application are highly assured. This study will therefore discuss the potential of vitamin D supplementation as a preventive and therapeutic agent in combination with other strategies, as this vitamin meets all the criteria described above. A variety of data are available on the association of vitamin D with respiratory infections and viral infections, as well as on the immune response by supplementation with this vitamin.Vitamin D deficiency adds to the variables that make people more susceptible to infection and the damaging development of COVID-19, as there is a correlation between its levels in the body and the severity of COVID-19 infections. Due to its direct antiviral and anti-inflammatory properties, it can be assumed that maintaining it within normal levels in the body is necessary to maintain the health of the body, and when its level in the body is below the optimal level, this can be compensated for with vitamin D supplements.","PeriodicalId":504355,"journal":{"name":"International Journal Of Health & Medical Research","volume":"68 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140971804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-07DOI: 10.58806/ijhmr.2024.v3i05n01
Dr P Lekha Priyadharshini, Dr V Jayaraman
BACKGROUND: The purpose of this study is to compare the duration of sensory and motor block in elective lower limb and abdominal procedures following intrathecal administration of bupivacaine along with adjuvants either clonidine or dexmedetomidine. METHODS: A prospective randomised double blinded study. 120 study participants were randomly allocated to three groups-Group A was given 12.5 mg of hyperbaric bupivacaine, Group B was given 3 mcg dexmedetomidine along with 12.5 mg hyperbaric bupivacaine and Group C was given 30 mcg of clonidine along with hyperbaric bupivacaine. The duration of sensory and motor block was recorded. RESULTS: Group B and C study participants showed significantly longer duration of sensory and motor block when compared to Group A. The mean duration of sensory block in Group A was 92.5 minutes, Group B 124.5 minutes Group C (119.4 minutes) (A vs B, A vs C p<0.001). The mean duration of motor block in group A 149.1 min, group B 252.5 min, Group C 217 min (A vs B, A vs C, B vs C P<0.001) CONCLUSION: By adding 3 mcg dexmedetomidine or 30 mcg clonidine to hyperbaric bupivacaine duration of sensory and motor block was significantly prolonged.
背景：本研究的目的是比较在择期下肢和腹部手术中鞘内注射布比卡因以及氯尼替丁或右美托咪定辅助剂后感觉和运动阻滞的持续时间。方法：前瞻性随机双盲研究。120 名参与者被随机分配到三组--A 组给予 12.5 毫克高压布比卡因，B 组在给予 12.5 毫克高压布比卡因的同时给予 3 微克右美托咪定，C 组在给予高压布比卡因的同时给予 30 微克氯尼替丁。记录感觉和运动阻滞的持续时间。结果：与 A 组相比，B 组和 C 组研究人员的感觉和运动阻滞持续时间明显更长。A 组的平均感觉阻滞持续时间为 92.5 分钟，B 组为 124.5 分钟，C 组为 119.4 分钟（A vs B，A vs C p<0.001）。A 组运动阻滞的平均持续时间为 149.1 分钟，B 组为 252.5 分钟，C 组为 217 分钟（A vs B，A vs C，B vs C P<0.001 结论：在高压布比卡因中加入 3 微克右美托咪定或 30 微克氯尼替丁可明显延长感觉和运动阻滞的持续时间。
{"title":"Effects Of Low Doses Of Intrathecal Clonidine And Dexmedetomidine With Bupivacaine On The Duration Of Sensory And Motor Block In Abdominal And Lower Limb Surgeries- A Prospective Randomised Double Blinded Study","authors":"Dr P Lekha Priyadharshini, Dr V Jayaraman","doi":"10.58806/ijhmr.2024.v3i05n01","DOIUrl":"https://doi.org/10.58806/ijhmr.2024.v3i05n01","url":null,"abstract":"BACKGROUND: The purpose of this study is to compare the duration of sensory and motor block in elective lower limb and abdominal procedures following intrathecal administration of bupivacaine along with adjuvants either clonidine or dexmedetomidine. METHODS: A prospective randomised double blinded study. 120 study participants were randomly allocated to three groups-Group A was given 12.5 mg of hyperbaric bupivacaine, Group B was given 3 mcg dexmedetomidine along with 12.5 mg hyperbaric bupivacaine and Group C was given 30 mcg of clonidine along with hyperbaric bupivacaine. The duration of sensory and motor block was recorded. RESULTS: Group B and C study participants showed significantly longer duration of sensory and motor block when compared to Group A. The mean duration of sensory block in Group A was 92.5 minutes, Group B 124.5 minutes Group C (119.4 minutes) (A vs B, A vs C p<0.001). The mean duration of motor block in group A 149.1 min, group B 252.5 min, Group C 217 min (A vs B, A vs C, B vs C P<0.001) CONCLUSION: By adding 3 mcg dexmedetomidine or 30 mcg clonidine to hyperbaric bupivacaine duration of sensory and motor block was significantly prolonged.","PeriodicalId":504355,"journal":{"name":"International Journal Of Health & Medical Research","volume":"116 s434","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141002722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The prognosis for pancreatic cancer (PC) is poor making it a substantial treatment challenge. A potentially effective treatment option is immunotherapy. To better understand the changing field of immunotherapy in PC management, this analysis will focus on important tactics and their consequences. To find relevant research published between 2019 and 2024, a thorough literature search was carried out using Scopus, Google Scholar, and PubMed. Tumor cells may be targeted and immune responses can be modulated using passive immunotherapeutic techniques such as CAR T-cell therapy and programmed death checkpoint inhibitors. Preclinical and clinical studies show enhanced effectiveness of combination therapy, such as anti-PD-1/anti-PD-L1 plus CTLA-4 inhibitors. Although their efficacy varies, active immunotherapeutic strategies, in particular cancer vaccines, seek to promote immune recognition of tumor antigens. Subpar response rates and treatment-related toxicity are obstacles. Checkpoint inhibitors, CAR T-cell therapy, and cancer vaccines are a few possible therapeutic options in the exciting field of immunotherapy for PC treatment. Nevertheless, further study is required to enhance these strategies and enhance patient.
胰腺癌（PC）的预后很差，因此治疗难度很大。免疫疗法是一种潜在的有效治疗方法。为了更好地了解免疫疗法在PC治疗领域的变化，本分析将重点关注重要策略及其后果。为了找到2019年至2024年期间发表的相关研究，我们使用Scopus、谷歌学术和PubMed进行了全面的文献检索。利用被动免疫治疗技术（如 CAR T 细胞疗法和程序性死亡检查点抑制剂）可以靶向肿瘤细胞并调节免疫反应。临床前和临床研究表明，联合疗法（如抗-PD-1/抗-PD-L1加CTLA-4抑制剂）可提高疗效。积极的免疫治疗策略，尤其是癌症疫苗，虽然疗效各异，但都旨在促进免疫系统识别肿瘤抗原。不理想的反应率和治疗相关毒性是这些疗法的障碍。检查点抑制剂、CAR T 细胞疗法和癌症疫苗是治疗 PC 的免疫疗法这一令人兴奋的领域中几种可能的治疗方案。不过，还需要进一步的研究来加强这些策略并提高患者的治疗效果。
{"title":"Emerging Trends In Immunotherapy Management For Pancreatic Cancer: A Literature Review","authors":"Jhonny Joel Calle Bravo, Nicole Stephanie Rodríguez Acurio, Jessica Valeria Medrano Aulestia, Tatiana Carolina Rosales Pavón, Delia Soledad Calle Cadme, Nathaly Paola Castro Moscoso","doi":"10.58806/ijhmr.2024.v3i03n10","DOIUrl":"https://doi.org/10.58806/ijhmr.2024.v3i03n10","url":null,"abstract":"The prognosis for pancreatic cancer (PC) is poor making it a substantial treatment challenge. A potentially effective treatment option is immunotherapy. To better understand the changing field of immunotherapy in PC management, this analysis will focus on important tactics and their consequences. To find relevant research published between 2019 and 2024, a thorough literature search was carried out using Scopus, Google Scholar, and PubMed. Tumor cells may be targeted and immune responses can be modulated using passive immunotherapeutic techniques such as CAR T-cell therapy and programmed death checkpoint inhibitors. Preclinical and clinical studies show enhanced effectiveness of combination therapy, such as anti-PD-1/anti-PD-L1 plus CTLA-4 inhibitors. Although their efficacy varies, active immunotherapeutic strategies, in particular cancer vaccines, seek to promote immune recognition of tumor antigens. Subpar response rates and treatment-related toxicity are obstacles. Checkpoint inhibitors, CAR T-cell therapy, and cancer vaccines are a few possible therapeutic options in the exciting field of immunotherapy for PC treatment. Nevertheless, further study is required to enhance these strategies and enhance patient.","PeriodicalId":504355,"journal":{"name":"International Journal Of Health & Medical Research","volume":"58 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140365122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-28DOI: 10.58806/ijhmr.2024.v3i3n09
Wiet Sidharta, A. Krismariono, Aristo Lay
Background: Gingival recession is apical migration of marginal gingiva, causing exposure of the root surface of the tooth.To treat this condition, free gingival autograft is used to increase the keratinized gingiva in the deformed area. The aim of the case is to prove the efficacy of Free Gingival Autograft technique in increasing amount of keratinized gingiva in area affected by gingival recession. Case presentation: In this clinical case presentation, a systemically healthy 61‑years‑old female come to the Periodontics Department of Airlangga Dental and Mouth Hospital seeking treatment for her mandibular front teeth which appeared to be elongated clinically and aesthetically unpleasing. Case management: The patient was treated by free gingival autograft. Graft is harvested from the palatal, placed, and sutured on the recipient site. 1 month post treatment follow up showed good result, evident with increased amount of keratinized mucosa in the previously deformed area. Conclusion: Gingival recession is a complex condition which can be treated with free gingival autograft. This technique showed satisfactory result, evident with increase of keratinized gingiva at 1 month follow-up.
{"title":"Gingival Recession Treatment With Utilization Of Free Gingival Autograft Technique: A Case Study","authors":"Wiet Sidharta, A. Krismariono, Aristo Lay","doi":"10.58806/ijhmr.2024.v3i3n09","DOIUrl":"https://doi.org/10.58806/ijhmr.2024.v3i3n09","url":null,"abstract":"Background: Gingival recession is apical migration of marginal gingiva, causing exposure of the root surface of the tooth.To treat this condition, free gingival autograft is used to increase the keratinized gingiva in the deformed area. The aim of the case is to prove the efficacy of Free Gingival Autograft technique in increasing amount of keratinized gingiva in area affected by gingival recession. Case presentation: In this clinical case presentation, a systemically healthy 61‑years‑old female come to the Periodontics Department of Airlangga Dental and Mouth Hospital seeking treatment for her mandibular front teeth which appeared to be elongated clinically and aesthetically unpleasing. Case management: The patient was treated by free gingival autograft. Graft is harvested from the palatal, placed, and sutured on the recipient site. 1 month post treatment follow up showed good result, evident with increased amount of keratinized mucosa in the previously deformed area. Conclusion: Gingival recession is a complex condition which can be treated with free gingival autograft. This technique showed satisfactory result, evident with increase of keratinized gingiva at 1 month follow-up.","PeriodicalId":504355,"journal":{"name":"International Journal Of Health & Medical Research","volume":"14 16","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140373389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: Tonsillectomy is the most common surgery in the field of ENT. Pain is the most common post tonsillectomy complaint. Considering the importance of nursing cares in relieving post-surgery pain in general and post-tonsillectomy pain in particular, this study is conducted To assess Nurses knowledge towards nursing care of tonsillectomy in children and To find out the relationship between the Nurses knowledge and their selected demographic variables of age ,gender, level of education, years of experience, and training session. Methods: A Non-probability purposive sample of ( 120) nurses who are working in the operation rooms, surgical units and Ear, nose and throat units in these hospitals .The study was carried out from January 1st, 2023 up to April 28th, 2023. Conclusion: there are high significant relationship between the nurses’ age, hospital and their knowledge related to nursing care of children with tonsillectomy and there is a non-significant relationship with the remaining demographic and clinical data.
{"title":"Improving Nurses’ Proficiency In Providing Nursing Care For Pediatric Tonsillectomy","authors":"Mohammed Baqer Hassan, Wamith Hamid Shaker, Asmahan Qasim Mohammed, Zainab Abidzaid Abid AL-Hadrawy","doi":"10.58806/ijhmr.2024.v3i3n08","DOIUrl":"https://doi.org/10.58806/ijhmr.2024.v3i3n08","url":null,"abstract":"Objective: Tonsillectomy is the most common surgery in the field of ENT. Pain is the most common post tonsillectomy complaint. Considering the importance of nursing cares in relieving post-surgery pain in general and post-tonsillectomy pain in particular, this study is conducted To assess Nurses knowledge towards nursing care of tonsillectomy in children and To find out the relationship between the Nurses knowledge and their selected demographic variables of age ,gender, level of education, years of experience, and training session. Methods: A Non-probability purposive sample of ( 120) nurses who are working in the operation rooms, surgical units and Ear, nose and throat units in these hospitals .The study was carried out from January 1st, 2023 up to April 28th, 2023. Conclusion: there are high significant relationship between the nurses’ age, hospital and their knowledge related to nursing care of children with tonsillectomy and there is a non-significant relationship with the remaining demographic and clinical data.","PeriodicalId":504355,"journal":{"name":"International Journal Of Health & Medical Research","volume":" 90","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140210454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-22DOI: 10.58806/ijhmr.2024.v3i3n07
C. Prahasanti, Michael Ganda Wijaya, Rahmidian Safitri, Hardini Dyah Astuti, Poernomo Agoes
Background: Drug induced gingival enlargement is frequently observed in patients taking three main group of drugs like calcium channel blockers (CCBs), immunosuppressant’s and anticonvulsants. Amlodipine belongs to the dihydropyridine-a third generation calcium channel blockers agents that may cause the side effect of drug-induced gingival enlargement and oral bacteria intervention due to calculus retention. This case report describes the management of gingival enlargement in a hypertensive patient taking amlodipine. Purpose: This case report was aimed to discuss the treatment and maintenance of systemic observationsurgical periodontic approach to restore gingival enlargement. Case Report: A 47-years old man was referred to the Department of Periodontology, Faculty of Dentistry, Airlangga University complaining of swellings and bleeding on his gingiva in all region. He felt very uncomfortable as the swelling interfered while chewing and sometimes there was bleeding spontaneously and halitosis. He had hypertension since 5 years and was on medications Captopril 12,5 mg daily during 4 years and Amlodipine 5mg daily during last 1 year. A provisional diagnosis and systemic observation-periodontal phases treatment were taken to restore gingival enlargement condition. Case Management: Systemic observation of medication use, periodontal phases treatment such as scaling root planning, periodontal surgery as flap surgery, home oral hygiene maintenance, control recall every month during first 3 months were taken. Conclusion: The successful of combination carefully systemic observation-surgery periodontal approach are promising to maintain Amlodipine induced gingival enlargement.
{"title":"Systemic Observation-Surgical Periodontic Approach In The Management Of Amlodipine Induced Gingival Enlargement","authors":"C. Prahasanti, Michael Ganda Wijaya, Rahmidian Safitri, Hardini Dyah Astuti, Poernomo Agoes","doi":"10.58806/ijhmr.2024.v3i3n07","DOIUrl":"https://doi.org/10.58806/ijhmr.2024.v3i3n07","url":null,"abstract":"Background: Drug induced gingival enlargement is frequently observed in patients taking three main group of drugs like calcium channel blockers (CCBs), immunosuppressant’s and anticonvulsants. Amlodipine belongs to the dihydropyridine-a third generation calcium channel blockers agents that may cause the side effect of drug-induced gingival enlargement and oral bacteria intervention due to calculus retention. This case report describes the management of gingival enlargement in a hypertensive patient taking amlodipine. Purpose: This case report was aimed to discuss the treatment and maintenance of systemic observationsurgical periodontic approach to restore gingival enlargement. Case Report: A 47-years old man was referred to the Department of Periodontology, Faculty of Dentistry, Airlangga University complaining of swellings and bleeding on his gingiva in all region. He felt very uncomfortable as the swelling interfered while chewing and sometimes there was bleeding spontaneously and halitosis. He had hypertension since 5 years and was on medications Captopril 12,5 mg daily during 4 years and Amlodipine 5mg daily during last 1 year. A provisional diagnosis and systemic observation-periodontal phases treatment were taken to restore gingival enlargement condition. Case Management: Systemic observation of medication use, periodontal phases treatment such as scaling root planning, periodontal surgery as flap surgery, home oral hygiene maintenance, control recall every month during first 3 months were taken. Conclusion: The successful of combination carefully systemic observation-surgery periodontal approach are promising to maintain Amlodipine induced gingival enlargement.","PeriodicalId":504355,"journal":{"name":"International Journal Of Health & Medical Research","volume":" 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140215357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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