Explore-The Journal of Science and Healing最新文献_第5页

Effects of the Rebozo technique on labor outcomes in primiparous women: A randomized controlled trial Rebozo技术对初产妇分娩结局的影响：一项随机对照试验

IF 2.2 4区医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE

Explore-The Journal of Science and Healing

Pub Date : 2025-11-01 DOI: 10.1016/j.explore.2025.103282

Zeynep Tuncay , Gulsen Cayir , Halime Sule Selman , Aysu Yldz Karaahmet

Aim

This study was conducted as a randomized controlled trial to examine the effect of the rebozo technique on labor duration, pain, and satisfaction in primiparous women.

Methods

The study was conducted between November 2022 and June 2023 in primiparous pregnant women who applied to a public hospital in Ankara for vaginal delivery. Pregnant women in the active phase were randomized, and 146 pregnant women, 73 in the Rebozo and 73 in the control group were included. Mother-infants were evaluated during labor and the postpartum period. Data were collected using the Descriptive Information Form, State Anxiety Scale, Birth Follow-up Form, Visual Analog Scale, and Birth Satisfaction Scale. Pregnant women in the rebozo group underwent rebozo techniques for an average of 10-15 minutes from the active phase to delivery with a rebozo shawl during contraction, according to the pregnant woman's preference.

Results

In the rebozo group, the second stage of labor and placenta expulsion time was significantly shorter; episiotomy, laceration, the need to change pads in the first 2 hours postpartum, and the decrease in blood HTC value were found to be less. In the Rebozo group, Postpartum Maternal State Anxiety Scale and Visual Analog Scale Pain measurements were significantly lower, birth satisfaction was higher, and they preferred vaginal delivery in their subsequent births.

Conclusions

The use of Rebozo techniques in the labor process had many benefits for the labor and postpartum period and had no negative effects on maternal, fetal, and neonatal health.

目的本研究是一项随机对照试验，旨在探讨rebozo技术对初产妇产程、疼痛和满意度的影响。方法研究于2022年11月至2023年6月在安卡拉一家公立医院申请阴道分娩的初产妇。随机选取活动期孕妇146例，其中73例为Rebozo组，73例为对照组。在分娩和产后对母婴进行评估。采用描述性信息表、状态焦虑量表、分娩随访表、视觉模拟量表和分娩满意度量表收集数据。根据孕妇的喜好，rebozo组的孕妇从活跃期到在宫缩期间使用rebozo披肩分娩，平均需要10-15分钟。结果中药组第二产程及胎盘排出时间明显缩短；外阴切开术、撕裂伤、产后前2小时需要更换垫、血HTC值下降较少。在Rebozo组，产后产妇状态焦虑量表和视觉模拟量表疼痛测量明显较低，分娩满意度较高，她们在随后的分娩中更倾向于阴道分娩。结论在分娩过程中使用Rebozo技术对产程和产后有许多好处，对产妇、胎儿和新生儿的健康没有负面影响。

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引用次数: 0

Limb-saving integrative Chinese-western therapy for necrotizing fasciitis: A case report and literature review 中西医结合保肢疗法治疗坏死性筋膜炎1例并文献复习

IF 2.2 4区医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE

Explore-The Journal of Science and Healing

Pub Date : 2025-11-01 DOI: 10.1016/j.explore.2025.103275

Xu Sun , Jielin Song , Xuelian Zhao , Zhaohui Zhang , Junchao Sun

Background

Necrotizing fasciitis (NF) of the lower leg is a severe, potentially fatal aggressive infection. Untimely treatment frequently leads to amputation or even life-threatening outcomes.

Case Presentation

This case report presents a limb-salvage and life-saving strategy integrating Traditional Chinese Medicine (TCM) and Western medicine in a 93-year-old male patient with lower extremity necrotizing fasciitis who refused amputation. The integrated treatment plan included: early surgical incision with debridement, nose ring drainage, broad-spectrum antibiotics, and symptomatic supportive therapy. Local wound irrigation was performed with rhubarb-licorice decoction, supplemented by topical galla chinensis paste application and oral administration of Si-Miao-Yong-An Decoction and Siwu Decoction. During the intermediate phase, limited additional debridement was performed, followed by local chymotrypsin and lithospermum gauze application. After optimal wound bed preparation, split-thickness stamp skin grafting was performed. Postoperatively, Vaseline gauze and lithospermum gauze were applied alternately with intermittent closed drainage. The oral TCM regimen was subsequently adjusted to Buzhong Yiqi Decoction.

Conclusion

This integrative approach effectively addressed infection control, systemic inflammation, and tissue regeneration, demonstrating its potential as a limb-preserving alternative for NF patients when standard surgery is contraindicated or declined. Further studies are warranted to validate these findings.

背景：下肢坏死性筋膜炎（NF）是一种严重的、具有潜在致命性的侵袭性感染。不及时的治疗常常导致截肢，甚至危及生命。本病例报告介绍了一名拒绝截肢的93岁男性下肢坏死性筋膜炎患者的中西医结合保肢救命策略。综合治疗方案包括：早期手术切口清创、鼻环引流、广谱抗生素、对症支持治疗。用大黄甘草煎液局部创面冲洗，辅以五倍子膏外敷，口服四苗永安汤、四物汤。在中间阶段，进行有限的额外清创，然后局部应用凝乳胰蛋白酶和紫砂纱布。在最佳的创面准备后，进行分厚度的邮票皮移植。术后交替涂抹凡士林纱布和紫砂纱布，间歇闭式引流。随后将中药口服方案调整为补中益气汤。结论：这种综合方法有效地解决了感染控制、全身性炎症和组织再生问题，在标准手术禁忌或拒绝的情况下，证明了其作为NF患者肢体保留替代方案的潜力。需要进一步的研究来证实这些发现。

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引用次数: 0

Management of the seasonal mood-sleep-fatigue symptom cluster in Parkinson's disease: Methodological insights from a cassia oil aromatherapy trial 帕金森病季节性情绪-睡眠-疲劳症状群的管理：决明子油芳香疗法试验的方法学见解

IF 2.2 4区医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE

Explore-The Journal of Science and Healing

Pub Date : 2025-11-01 DOI: 10.1016/j.explore.2025.103276

Fei-Yi Zhao , Yan-Mei Wang , Qiang-Qiang Fu , Jia-Yi Zhu , Jie Qian

引用次数: 0

Rethinking communication and consciousness: Lessons from the telepathy tapes podcast 重新思考沟通和意识：来自心灵感应磁带播客的教训。

IF 2.2 4区医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE

Explore-The Journal of Science and Healing

Pub Date : 2025-11-01 DOI: 10.1016/j.explore.2025.103271

Marina Weiler , Marjorie Woollacott

In late 2024, The Telepathy Tapes podcast ignited global debate by spotlighting nonspeaking autistic individuals who appeared to convey knowledge beyond ordinary sensory channels. For some, the series offered overdue recognition of nonspeakers’ intelligence and agency; for others, it represented a revival of the discredited practice of Facilitated Communication. This controversy reflects deeper cultural and scientific assumptions: nonspeakers have long been misclassified as profoundly intellectually disabled, with their lack of speech equated with a lack of thought. Yet emerging evidence increasingly challenges this deficit model, with recent empirical findings supporting authorship and intentionality. At the same time, anecdotal reports of anomalous—potentially telepathic—communication, though contentious, warrant consideration in light of prior parapsychological research. We contend that The Telepathy Tapes marks a cultural turning point, compelling a reassessment of entrenched scientific frameworks and ethical stances toward nonspeakers. We advocate that the podcast should be considered a filmmaker’s curious exploration of the phenomenon, which will engender the curiosity of scientists to move forward with carefully controlled experiments. Moving forward, a less stigmatized and more open-minded approach is needed—one that recognizes carefully documented anecdotes as valuable starting points for rigorous empirical inquiry.

2024年末，《心灵感应磁带》（The Telepathy Tapes）播客通过关注不会说话的自闭症患者，引发了全球辩论，这些自闭症患者似乎能传递超越普通感官渠道的知识。对一些人来说，这一系列节目对不会说话的人的智力和能动性给予了迟来的认可；对另一些人来说，它代表了名誉扫地的“促进沟通”的复兴。这场争论反映了更深层次的文化和科学假设：不会说话的人长期以来被错误地归类为严重的智力残疾，他们不会说话就等同于缺乏思考。然而，新出现的证据越来越多地挑战这一缺陷模型，最近的实证研究结果支持作者和意向性。与此同时，关于异常——潜在的心灵感应——交流的轶事报道，尽管有争议，但根据先前的超心理学研究，值得考虑。我们认为，《心灵感应磁带》标志着一个文化转折点，迫使人们重新评估根深蒂固的科学框架和对非语言者的伦理立场。我们主张，播客应该被视为电影制作人对这一现象的好奇探索，这将激发科学家的好奇心，推动他们进行精心控制的实验。展望未来，我们需要一种不那么污名化、更开放的方法——一种将精心记录的轶事视为严谨实证调查的宝贵起点的方法。

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引用次数: 0

Masthead page 报头页面

IF 2.2 4区医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE

Explore-The Journal of Science and Healing

Pub Date : 2025-11-01 DOI: 10.1016/S1550-8307(25)00187-9

引用次数: 0

Effect of self-acupressure on fatigue and sleep quality in patients with multiple sclerosis: A randomized controlled trial 自我穴位按压对多发性硬化症患者疲劳和睡眠质量的影响：一项随机对照试验

IF 2.2 4区医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE

Explore-The Journal of Science and Healing

Pub Date : 2025-11-01 DOI: 10.1016/j.explore.2025.103266

Gülden Atan

Objective

This study aimed to assess the efficacy of self-acupressure in alleviating fatigue and enhancing sleep quality among individuals diagnosed with multiple sclerosis.

Methods

In our randomized controlled study, participants in the intervention group were instructed to administer self-acupressure on two specific sites. Patients were directed to administer the therapy to the specified two sites biweekly in the morning, at least one hour after breakfast, for a duration of 4 weeks, culminating in a total of 8 sessions. No intervention occurred in the control group during this study. Data were gathered utilizing the Patient Introductory Information Form, the Fatigue Severity Scale (FSS), and the Richards-Campbell Sleep Questionnaire (RCSQ).

Results

The study comprised twenty-four individuals with multiple sclerosis in each group, comprising fourteen women in the intervention group and thirteen women in the control group. Subsequent to the intervention, the intervention group demonstrated a statistically significant decrease in total FSS scores compared to the control group (p < 0.001; d = 1.68), although total RCSQ scores revealed a substantial gain (p < 0.001; d = 1.65).

Conclusion

Self-acupressure was proven to reduce fatigue levels and improve sleep quality in adults with multiple sclerosis. In conclusion, self-acupressure is an accessible, cost-effective, and efficacious technique for alleviating fatigue and enhancing sleep quality in patients with multiple sclerosis.

目的探讨自我穴位按压对多发性硬化症患者缓解疲劳、提高睡眠质量的作用。方法在随机对照研究中，干预组受试者被指示在两个特定部位进行自我穴位按压。指导患者每两周在早餐后至少一小时的早晨对指定的两个部位进行治疗，持续4周，总共8次。在本研究中，对照组未进行干预。使用患者介绍信息表、疲劳严重程度量表（FSS）和Richards-Campbell睡眠问卷（RCSQ）收集数据。结果每组24例多发性硬化症患者，干预组14例，对照组13例。干预后，干预组的FSS总分与对照组相比有统计学意义上的显著下降（p < 0.001; d = 1.68），尽管RCSQ总分有显著提高（p < 0.001; d = 1.65）。结论自我穴位按摩可减轻成人多发性硬化症患者的疲劳程度，改善睡眠质量。综上所述，自我穴位按压对于缓解多发性硬化症患者的疲劳和提高睡眠质量是一种方便、经济、有效的技术。

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引用次数: 0

Clinical efficacy of Guishao Shengxue decoction in the treatment of pediatric immune thrombocytopenia: A randomized controlled trial 桂芍生血汤治疗小儿免疫性血小板减少症的临床疗效：随机对照试验。

IF 2.2 4区医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE

Explore-The Journal of Science and Healing

Pub Date : 2025-11-01 DOI: 10.1016/j.explore.2025.103277

Wei Wang , Xiaofei Xie , Shengtao Cui , Lin Xue

Background

Current treatments for pediatric immune thrombocytopenia (ITP) are effective but often associated with significant side effects, highlighting the need for safer and more sustainable alternatives. The objective of this study is to evaluate the clinical efficacy and safety of Guishao Shengxue Decoction (GSD) as a complementary therapy for ITP, aiming to provide a safer and more sustainable alternative to conventional treatments.

Methods

In this randomized, double-blind study, 42 children with persistent or chronic ITP were enrolled and allocated equally to treatment or control groups. The treatment group received GSD combined with conventional therapy, while the control group received a placebo combined with conventional therapy for six months. Efficacy outcomes included platelet parameters, immune and hematological markers, and safety evaluations.

Results

The treatment group demonstrated higher complete response (33.33% vs. 14.29%), overall response rate (95.24% vs. 71.43%), and durable response (95.24% vs. 80.95%) compared to the control group. Platelet indices and hematological parameters improved significantly in the treatment group, along with reduced platelet-associated immunoglobulins and better immune modulation.

Conclusions

GSD enhances clinical outcomes, supports platelet recovery, and modulates immune function in pediatric ITP, offering a safe and effective adjunct to conventional therapy.

背景：目前儿童免疫性血小板减少症（ITP）的治疗是有效的，但往往伴有显著的副作用，这突出了对更安全、更可持续的替代方案的需求。本研究旨在评价桂芍生血汤（GSD）作为ITP补充治疗的临床疗效和安全性，以期提供一种更安全、更可持续的替代常规治疗方法。方法：在这项随机双盲研究中，42名患有持续性或慢性ITP的儿童被纳入研究，并被平均分配到治疗组和对照组。治疗组采用GSD联合常规治疗，对照组采用安慰剂联合常规治疗，疗程6个月。疗效指标包括血小板参数、免疫和血液学指标以及安全性评价。结果：治疗组完全缓解率（33.33% vs. 14.29%）、总缓解率（95.24% vs. 71.43%）、持续缓解率（95.24% vs. 80.95%）均高于对照组。治疗组血小板指数和血液学参数明显改善，血小板相关免疫球蛋白降低，免疫调节改善。结论：GSD可改善儿童ITP的临床结果，支持血小板恢复，调节免疫功能，为常规治疗提供安全有效的辅助。

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引用次数: 0

Traditional Chinese medicine as an adjunctive strategy in long-term management of colorectal cancer liver metastasis: A case report 中医药作为结直肠癌肝转移长期治疗的辅助策略1例报告

IF 2.2 4区医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE

Explore-The Journal of Science and Healing

Pub Date : 2025-11-01 DOI: 10.1016/j.explore.2025.103281

Nan Li, Shulan Hao, Likun Liu, Xixing Wang

Background

Colorectal cancer liver metastasis (CRLM) is one of the leading causes of death among patients with colorectal cancer, characterized by poor prognosis and a high recurrence rate. Although multidisciplinary treatments, including surgical resection, chemotherapy, targeted therapy, and immunotherapy, can prolong survival, some patients fail to tolerate or sustain these therapies due to drug resistance or adverse effects. In recent years, Traditional Chinese Medicine (TCM) has attracted increasing attention as an adjunctive approach for improving symptoms, enhancing treatment tolerance, and potentially extending survival.

Case Summary

We report a 52-year-old male patient with CRLM who underwent two hepatic resections, radiotherapy, multiple lines of chemotherapy and targeted therapy, as well as radiofrequency ablation. Guided by TCM, he received long-term oral decoctions based on the therapeutic principle of gong-bu jian-shi (simultaneous reinforcement and elimination), which aims to strengthen vital Qi while removing pathogenic factors. Despite limited tolerance to systemic therapies, the patient maintained prolonged disease stability and achieved an overall survival of 11 years after the initial diagnosis of liver metastasis in 2013. In 2024, following SARS-CoV-2 infection, he developed duodenal ulceration and multiorgan progression, eventually succumbing to disease deterioration.

Conclusion

This case highlights the potential role of TCM as an adjunct in the long-term integrative management of CRLM. Through reinforcing vital Qi, eliminating pathogenic factors, and harmonizing Yin and Yang, TCM may improve systemic function, enhance treatment tolerance, and delay disease progression. When conventional treatments are limited, TCM may serve as a valuable complementary strategy, providing new insights into individualized and long-term management of colorectal cancer liver metastasis.

结直肠癌肝转移（colorectal cancer liver metastasis， CRLM）是结直肠癌患者死亡的主要原因之一，其特点是预后差、复发率高。尽管包括手术切除、化疗、靶向治疗和免疫治疗在内的多学科治疗可以延长生存期，但由于耐药或不良反应，一些患者不能耐受或维持这些治疗。近年来，中医作为一种改善症状、提高治疗耐受性和延长生存期的辅助手段，越来越受到人们的关注。我们报告了一位52岁的CRLM男性患者，他接受了两次肝切除术，放疗，多线化疗和靶向治疗，以及射频消融。在中医的指导下，他接受了长期的口服煎剂治疗，这是基于“同时补消”的治疗原则，旨在增强正气，同时去除致病因素。尽管对全身治疗的耐受性有限，但在2013年首次诊断为肝转移后，患者维持了较长的疾病稳定性，并实现了11年的总生存期。2024年，在SARS-CoV-2感染后，他出现了十二指肠溃疡和多器官进展，最终因疾病恶化而死亡。结论本病例强调了中医药在慢性粒细胞白血病长期综合治疗中的潜在作用。通过补气、祛邪、调和阴阳，中医可以改善全身功能，增强治疗耐受性，延缓疾病进展。在常规治疗有限的情况下，中医药可作为一种有价值的补充策略，为大肠癌肝转移的个体化和长期治疗提供新的见解。

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引用次数: 0

Massage and electroacupuncture as a combined method versus epidural analgesia for chronic low back pain management 按摩和电针作为联合方法与硬膜外镇痛治疗慢性腰痛

IF 2.2 4区医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE

Explore-The Journal of Science and Healing

Pub Date : 2025-11-01 DOI: 10.1016/j.explore.2025.103279

Fotini Papanikolaou , Metaxia Bareka , Christina Karatzaferi , Giorgos K. Sakkas , Violeta Roka , Ioannis Liampas , Mairy Gouva , Eleni Arnaoutoglou

Background

Chronic low back pain (CLBP) is a widespread issue, affecting 21 % to 68 % of adults, and holistic management with individualized treatments are recommended.

Purpose

The aim was to compare the effectiveness of two combined methods, massage and electroacupuncture (MA), versus epidural analgesia (EP) in managing pain, functionality, mood, and quality of life in patients with CLBP.

Materials and Methods

This study is a prospective randomized, controlled, assessor-blinded, interventional clinical trial. One Hundred and ten (110) participants (age 48.5 ± 2.9, 45M/65F) were randomly divided into two groups: 1) Massage – Electroacupuncture (MA) receiving 8 weekly sessions once a week and 2) Epidural analgesia (EP) receiving 3 epidural injections, every 15 days. Participants completed validated questionnaires assessing pain, mood, functionality, and quality of life for four (4) intervals, before and after treatment, 24- and 48-weeks’ follow-up respectively.

Results

Statistically significant improvements in pain relief for the MA group compared to EP, as measured by the NRS scale (p < 0.001) were observed. However, both groups exhibited similar outcomes regarding mood, functionality, and quality of life, with the MA group showing slight superiority, especially at the 24-week follow-up. Between-group adjustments over time represented relatively greater or earlier improvements in the MA group, as observed by the negative values obtained by the sample in the measurements.

Conclusion

The MA method could offer a comprehensive and potentially effective approach to pain management in CLBP patients compared to EP. The findings support the integration of combined treatments as part of a holistic approach for the management of CLBP.

背景：慢性腰痛（CLBP）是一个普遍的问题，影响了21%至68%的成年人，建议采用个性化治疗的整体管理。目的比较按摩和电针（MA）两种联合方法与硬膜外镇痛（EP）在控制CLBP患者疼痛、功能、情绪和生活质量方面的有效性。材料与方法本研究是一项前瞻性、随机、对照、评估盲、干预性临床试验。110名参与者（年龄48.5±2.9岁，45岁/65岁）随机分为两组：1)按摩-电针（MA）每周8次，每周一次；2)硬膜外镇痛（EP）接受3次硬膜外注射，每15天一次。参与者分别在治疗前后、24周和48周的随访中完成了四(4)个间隔的疼痛、情绪、功能和生活质量评估问卷。结果通过NRS量表（p < 0.001）观察到，与EP相比，MA组疼痛缓解有统计学意义上的显著改善。然而，两组在情绪、功能和生活质量方面表现出相似的结果，MA组表现出轻微的优势，特别是在24周的随访中。随着时间的推移，组间调整在MA组中表现出相对更大或更早的改善，正如测量中样本获得的负值所观察到的那样。结论与EP相比，MA方法可为CLBP患者提供全面有效的疼痛管理方法。研究结果支持将联合治疗作为CLBP管理整体方法的一部分。

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引用次数: 0

Integrative therapy with moxibustion and repetitive transcranial magnetic stimulation enhances outcomes in patients with post-stroke depression 艾灸和反复经颅磁刺激相结合的综合治疗可提高脑卒中后抑郁症患者的预后

IF 2.2 4区医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE

Explore-The Journal of Science and Healing

Pub Date : 2025-11-01 DOI: 10.1016/j.explore.2025.103280

Yating Song , Rui Chu , Yajing Ren , Miao Liu

Background

Post-stroke depression (PSD) affects 30–60 % of stroke survivors and significantly impairs rehabilitation outcomes. While selective serotonin reuptake inhibitors remain standard treatment, they often have limited efficacy and notable side effects. This study investigated whether combining Governor Vessel-regulating and depression-relieving moxibustion with repetitive transcranial magnetic stimulation (rTMS) could enhance treatment outcomes compared to escitalopram alone.

Methods

In this prospective comparative study, 120 PSD patients treated at our hospital from December 2021 to December 2023 were enrolled and assigned to control (n = 60) or study groups (n = 60) based on treatment allocation. The control group received escitalopram oxalate (Lexapro) 10 mg daily. The study group received escitalopram plus Governor Vessel-regulating and depression-relieving moxibustion (30 min daily) and 1 Hz rTMS (20 min, 5 times weekly) for 4 weeks. Primary outcomes included Hamilton Depression Rating Scale (HAMD) scores and treatment effectiveness.

Results

The study group demonstrated significantly greater improvements than controls across all measures: lower post-treatment HAMD scores (p < 0.05), higher total effectiveness rate (96.67 % vs 80.00 %, p < 0.05), reduced inflammatory markers (TNF-α and IL-6, both p < 0.05), improved neurological function (lower NIHSS scores, p < 0.05), better daily living activities (higher Barthel Index, p < 0.05), and fewer adverse reactions (3.33 % vs 15.00 %, p < 0.05).

Conclusion

The combination of Governor Vessel-regulating and depression-relieving moxibustion with rTMS and escitalopram significantly outperformed escitalopram monotherapy for PSD, offering enhanced antidepressant effects, reduced inflammation, improved neurological recovery, and better tolerability. This integrative approach represents a promising therapeutic strategy for post-stroke depression management.

脑卒中后抑郁（PSD）影响了30 - 60%的脑卒中幸存者，并显著影响康复结果。虽然选择性血清素再摄取抑制剂仍然是标准的治疗方法，但它们的疗效有限，副作用明显。本研究旨在探讨与艾司西酞普兰单独治疗相比，联合调节督血管和缓解抑郁艾灸与重复经颅磁刺激（rTMS）是否能提高治疗效果。方法本前瞻性比较研究纳入2021年12月至2023年12月在我院治疗的120例PSD患者，根据治疗分配分为对照组（n = 60）和研究组（n = 60）。对照组给予草酸艾司西酞普兰（Lexapro） 10 mg / d。实验组患者给予艾司西酞普兰加总督血管调节和抑郁艾灸（每日30分钟）和1 Hz rTMS（20分钟，每周5次），疗程4周。主要结局包括汉密尔顿抑郁评定量表（HAMD）评分和治疗效果。结果研究组在治疗后HAMD评分较低（p < 0.05），总有效率较高（96.67%比80.00 %,p < 0.05），炎症标志物（TNF-α和IL-6， p < 0.05）降低，神经功能改善（NIHSS评分较低，p < 0.05），日常生活活动改善（Barthel指数较高，p < 0.05），不良反应减少（3.33%比15.00%,p < 0.05）。结论经颅磁刺激联合艾司西酞普兰治疗PSD明显优于艾司西酞普兰单药治疗，抗抑郁作用增强，炎症减轻，神经功能恢复改善，耐受性更好。这种综合方法代表了卒中后抑郁管理的一种有前途的治疗策略。

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引用次数: 0