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Multimodal benefits of hypnosis on pain, mental health, sleep, and quality of life in patients with chronic pain related to fibromyalgia: A randomized, controlled, blindly-evaluated trial 催眠对纤维肌痛相关慢性疼痛患者的疼痛、心理健康、睡眠和生活质量的多模式益处:一项随机、对照、盲测试验。
IF 1.9 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-06-11 DOI: 10.1016/j.explore.2024.103016
Daniela Caputo Dorta , Paulo Oliveira Colavolpe , Pedro Santana Sales Lauria , Renata Barbosa Fonseca , Vitória Cézar Santos Gonçalves Brito , Cristiane Flora Villarreal

Background and purpose

Fibromyalgia is a chronic syndrome marked by intense musculoskeletal pain often refractory to pharmacological treatment. Although studies have shown that hypnosis improves fibromyalgia pain, gaps in experimental design limit their reliability. This work aimed to evaluate the effects of hypnosis on pain, mental health, sleep, and quality of life in participants with fibromyalgia chronic pain.

Methods

In this prospective, parallel, randomized, controlled, blindly-evaluated trial, participants of both sexes (n = 49) diagnosed with fibromyalgia and with moderate to severe chronic pain attended 8 weekly 1-h sessions with a hypnotherapist. For the hypnosis group (n = 24), sessions consisted in induction of hypnotic trance followed by suggestions to promote analgesia. For the control group (n = 25), sessions consisted in casual unscripted conversation. Participants were assessed at baseline (7 days before), post-intervention (7 days after), and follow-up (3 months after). The primary outcome was pain intensity. The secondary outcomes were the sensory and affective dimensions of pain; pain unpleasantness; pain catastrophizing; anxiety and depression; sleep quality; fibromyalgia impact; and quality of life.

Results

Hypnosis significantly reduced pain scores both at post-intervention and follow-up in comparison with baseline. The analgesic effect of hypnosis combined with pharmacological treatment lasted for at least 3 months and was superior to analgesia promoted by first- and second-line pharmacological treatment alone. Hypnosis significantly improved all parameters evaluated as secondary outcomes both at post-intervention and follow-up without inducing adverse events.

Conclusion

Our results corroborate that clinical hypnosis is an effective and feasible tool for managing chronic pain and other symptoms of fibromyalgia.

背景和目的:纤维肌痛是一种慢性综合征,以强烈的肌肉骨骼疼痛为特征,药物治疗往往难以奏效。尽管有研究表明催眠能改善纤维肌痛,但实验设计上的缺陷限制了其可靠性。这项研究旨在评估催眠对纤维肌痛慢性疼痛患者的疼痛、心理健康、睡眠和生活质量的影响:在这项前瞻性、平行、随机、对照、盲测试验中,被诊断患有纤维肌痛并伴有中度至重度慢性疼痛的男女参与者(n = 49)参加了催眠治疗师每周 8 次每次 1 小时的治疗。催眠组(24 人)的课程包括诱导催眠恍惚,然后提出促进镇痛的建议。对照组(n = 25)的课程则包括随意的、无脚本的对话。分别在基线(干预前 7 天)、干预后(干预后 7 天)和随访(干预后 3 个月)时对参与者进行评估。主要结果是疼痛强度。次要结果是疼痛的感觉和情感维度、疼痛的不快感、疼痛的灾难化、焦虑和抑郁、睡眠质量、纤维肌痛的影响以及生活质量:结果:与基线相比,催眠能明显降低干预后和随访期间的疼痛评分。催眠结合药物治疗的镇痛效果至少持续了3个月,优于单独使用一线和二线药物治疗的镇痛效果。在干预后和随访期间,催眠明显改善了作为次要结果评估的所有参数,且不会引起不良反应:我们的研究结果证实,临床催眠是治疗慢性疼痛和纤维肌痛其他症状的一种有效可行的工具。
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引用次数: 0
Effects of a traditional herbal formula containing Melissa officinalis, Pimpinella anisum, and Rosa damascena on anxiety and depression in patients with constipation-predominant irritable bowel syndrome (IBS-C): A double-blind randomized clinical trial 含有 Melissa officinalis、Pimpinella anisum 和大马士革蔷薇的传统草药配方对便秘为主的肠易激综合征(IBS-C)患者焦虑和抑郁的影响:双盲随机临床试验。
IF 1.9 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-05-29 DOI: 10.1016/j.explore.2024.05.011
Maryam Azimi , Hossein Karimi Dokht Shahrbabaki , Mahboobeh Raeiszadeh , Omid Eslami

Introduction

Irritable bowel syndrome (IBS) is associated with a high prevalence of anxiety and depression. This study aimed to evaluate the effects of a traditional Persian herbal formula containing Melissa officinalis, Pimpinella anisum, and Rosa damascena (MPR) on anxiety and depression in IBS patients with symptoms of constipation-predominant IBS (IBS-C).

Methods

This double-blind randomized clinical trial was conducted in Afzalipour Hospital via block randomization method. A total of 96 IBS-C patients (based on Rome IV criteria), aged 18–60 years, were included in this study. Participants received capsules containing either 500 mg of herbal formula or placebo (cornstarch) twice a day for four weeks Anxiety and depression were assessed using the Hospital Anxiety and Depression Scale.

Results

Forty-three patients in the intervention group and 45 patients in the control group completed this study. Except for the education level, there were no significant differences in the demographic characteristics between the two groups (P > 0.05). The mean levels of anxiety and depression, and total IBS symptom severity score showed no significant differences between the two groups at baseline (P > 0.05). After four weeks of treatment, the anxiety score considerably improvement in the treatment group (Cohen's d = -1.19, 95 % confidence intervals [CIs] -4.49 to 2.13), as did the depression score (Cohen's d = -1.93, 95 % CIs -4.32 to 2.79).

Conclusion

MPR considerably improved anxiety and depression in patients with IBS-C compared to the placebo without serious side effects.

简介肠易激综合征(IBS)与高发的焦虑和抑郁有关。本研究旨在评估一种含有 Melissa officinalis、Pimpinella anisum 和大马士革蔷薇(MPR)的传统波斯草药配方对便秘为主的肠易激综合征(IBS-C)患者焦虑和抑郁的影响:这项双盲随机临床试验在阿夫扎利普尔医院通过区组随机法进行。共有 96 名 18-60 岁的 IBS-C 患者(根据罗马 IV 标准)参与了这项研究。参与者服用含有 500 毫克草药配方或安慰剂(玉米淀粉)的胶囊,每天两次,连续服用四周:干预组和对照组分别有 43 名和 45 名患者完成了本研究。除教育程度外,两组患者的人口统计学特征无显著差异(P>0.05)。两组患者的焦虑和抑郁平均水平以及肠易激综合征症状严重程度总分在基线时无明显差异(P>0.05)。治疗四周后,治疗组的焦虑评分明显改善(Cohen's d = -1.19, 95 % 置信区间 [CIs] -4.49 to 2.13),抑郁评分也有所改善(Cohen's d = -1.93, 95 % 置信区间 -4.32 to 2.79):结论:与安慰剂相比,MPR能显著改善肠易激综合征(IBS-C)患者的焦虑和抑郁状况,且无严重副作用。
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引用次数: 0
Prevalence and determinants of massage therapy use in the U.S.: Findings from the 2022 National Health Interview Survey 美国使用按摩疗法的流行率和决定因素:2022 年全国健康访谈调查的结果。
IF 1.9 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-05-25 DOI: 10.1016/j.explore.2024.05.013
Jeff Levin , Matt Bradshaw

Background

This study presents findings on the prevalence and determinants of past-year massage therapy use among U.S. adults from the 2022 round of the National Health Interview Survey (NHIS) (total available N = 27,651), an annual national population survey.

Methods

The NHIS uses face-to-face interviews on a representative sample of the civilian, noninstitutionalized U.S. population drawn using a systematic, stratified, single-stage probability design. The analyses consist of logistically modeling the determinants of three outcome (dependent) measures: past year utilization of a practitioner of massage, past year utilization of massage for pain, and past-year utilization of massage to restore overall health. Exposure (independent) variables include numerous sociodemographic, health services, health-related, mental health and well-being, and behavioral indicators.

Results

The past-year prevalence rate for visiting a massage therapist in the U.S. is 11.1 %. The past-year rate for massage visits for pain is 6.0 %, and for restoring overall health is 8.5 %. Significantly higher rates are found among females and socioeconomically advantaged individuals, among other categories, and the strongest net determinant of massage therapy utilization is use of complementary or integrative practitioners.

Conclusion

It is apparent that massage therapy is a commonly utilized therapeutic modality in the U.S. While use of complementary or integrative therapies is a significant determinant of massage utilization, it may not be fitting to consider massage therapy itself as an “alternative” therapy, but rather a widely used and increasingly mainstream therapeutic modality meriting wider integration into the community of healthcare professions.

背景:本研究介绍了美国年度全国人口调查--全国健康访谈调查(NHIS)2022年的调查结果显示的美国成年人在过去一年中使用按摩疗法的普遍程度和决定因素(总人数=27,651):国家健康访谈调查采用系统、分层、单阶段概率设计,对美国平民、非住院人口中具有代表性的样本进行面对面访谈。分析包括对三个结果(因果)指标的决定因素进行逻辑建模:过去一年中按摩从业者的使用情况、过去一年中按摩治疗疼痛的使用情况以及过去一年中按摩恢复整体健康的使用情况。暴露(独立)变量包括众多社会人口、医疗服务、健康相关、心理健康和幸福感以及行为指标:在美国,过去一年去看按摩师的比例为 11.1%。过去一年中,因疼痛而去看按摩师的比例为 6.0%,因恢复整体健康而去看按摩师的比例为 8.5%。除其他类别外,女性和社会经济条件较好的人接受按摩治疗的比例明显较高,而使用按摩治疗的最强净决定因素是使用辅助或综合从业人员:虽然使用辅助或综合疗法是决定按摩使用率的一个重要因素,但将按摩疗法本身视为一种 "替代 "疗法可能并不恰当,按摩疗法是一种广泛使用且日益成为主流的治疗方式,应更广泛地融入医疗保健行业。
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引用次数: 0
The effects of aromatherapy massage in menopausal women with knee osteoarthritis: A randomized controlled study 香薰按摩对患有膝骨关节炎的更年期妇女的影响:随机对照研究
IF 1.9 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-05-23 DOI: 10.1016/j.explore.2024.05.012
Şerife İrem Döner , Hasan Gerçek , Özlem Akkoyun Sert , Ayça Aytar , Aydan Aytar

Objective

Knee Osteoarthritis (OA)’s prevalence increases during menopause. Aromatherapy massage with different oils is applied in the treatment of knee OA. The aim of this study was to determine the effects of aromatherapy massage with Bergamot essential oil (BEO) on pain, functionality, sleep quality and menopausal symptoms in menopausal women with knee OA.

Materials and methods

This study included 60 menopausal participants diagnosed with grade II-III OA. Participants were randomly divided into three groups: BEO (n=20), placebo (n=20) and control (n=20). The participants in the BEO group, received aromatherapy massage with BEO, in the placebo group aromatherapy massage with sweet almond oil was applied twice a week for 4 weeks. All participants underwent conventional physiotherapy. Visual Analog Scale was used to assess the severity of pain, Osteoarthritis Index to assess functionality, Pittsburgh Sleep Quality Index to assess sleep quality and Menopausal Symptoms Rating Scale to assess menopausal symptoms. All measurements were performed before and after the study.

Results

The results of the study showed that all three groups were effective on pain, functionality, sleep quality and menopausal symptoms (p<0.001). The results of the study showed that, aromatherapy massage with BEO was found to be more effective on functionality (p<0.001), pain (p<0.001) and menopausal symptoms (somatic and psychological symptoms) (p<0.001) compared to the control and placebo groups. It was determined that aromatherapy massage with BEO did not create a significant difference between the sleep quality scale scores in the control group and the placebo group (p=0.454).

Conclusion

This study found that aromatherapy massage with BEO improved functionality, reduced pain and menopausal symptoms, and did not affect sleep quality. We consider that its application in addition to routine treatment may be useful to reduce symptoms.

目的 膝关节骨性关节炎(OA)的发病率在更年期增加。使用不同精油的香薰按摩可用于治疗膝关节 OA。本研究旨在确定使用佛手柑精油(BEO)进行香薰按摩对患有膝关节 OA 的更年期妇女的疼痛、功能、睡眠质量和更年期症状的影响。参与者被随机分为三组:BEO组(20人)、安慰剂组(20人)和对照组(20人)。BEO组的参与者接受BEO香薰按摩,安慰剂组的参与者接受甜杏仁油香薰按摩,每周两次,持续4周。所有参与者都接受了常规物理治疗。采用视觉模拟量表评估疼痛的严重程度,采用骨关节炎指数评估功能,采用匹兹堡睡眠质量指数评估睡眠质量,采用更年期症状评定量表评估更年期症状。结果研究结果表明,三组对疼痛、功能、睡眠质量和更年期症状均有效(p<0.001)。研究结果表明,与对照组和安慰剂组相比,使用 BEO 的芳香疗法按摩对功能(p<0.001)、疼痛(p<0.001)和更年期症状(躯体和心理症状)(p<0.001)更有效。结论本研究发现,使用 BEO 进行芳香按摩可改善机能,减轻疼痛和更年期症状,且不影响睡眠质量。我们认为,除了常规治疗外,使用 BEO 可能有助于减轻症状。
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引用次数: 0
The effect of soy isoflavones given to women in the climacteric period on menopausal symptoms and quality of life: Systematic review and meta-analysis of randomized controlled trials 更年期妇女服用大豆异黄酮对更年期症状和生活质量的影响:随机对照试验的系统回顾和元分析
IF 1.9 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-05-22 DOI: 10.1016/j.explore.2024.05.010
Nuran GENÇTÜRK , Fatma Şule BİLGİÇ , Hülya Ulaşlı KABAN

Objective

This systematic review and meta-analysis aimed to examine the effect of soy isoflavones on menopausal symptoms and quality of life in climacteric women.

Method

The literature search was conducted in PubMed, CINAHL, Scopus, and Science Citation Index (Web of Science) until September 2023. This study is based on the recommendations of the Cochrane guidelines. The data were analysed using the Review Manager computer software (Version 5.4). The methodological quality of the studies was assessed with the RoB-2 tool.

Results

This analysis was completed with five studies and 425 climacteric women. According to the results of the analysis, menopausal symptoms (SMD: −0.49, 95 % CI: −1.13 to 0.16, Z = 1.47, p = 0.14), physical component (MD: −1.10, 95 % CI: −4.22 to 2.01, Z = 0.70, p = 0. 49) and mental component (MD: 0.81, 95 % CI: −6.73 to 8.35, Z = 0.21, p = 0.83), but there was a significant difference in depression level (SMD: −0.41, 95 % CI: −0.73 to −0.09, Z = 2.53, p = 0.01).

Conclusion

According to the results of the analysis, soy isoflavones had no effect on menopausal symptoms (vasomotor, psychosocial, physical, sexual, and urogenital complaints) and quality of life in climacteric women but did reduce the level of depression. There was a high risk of conflict of interest in the included studies.

PROSPERO database

Registration: CRD420234479700.

目的本系统综述和荟萃分析旨在研究大豆异黄酮对更年期症状和更年期女性生活质量的影响。方法在PubMed、CINAHL、Scopus和科学引文索引(Web of Science)中进行文献检索,直至2023年9月。本研究基于 Cochrane 指南的建议。数据使用 Review Manager 计算机软件(5.4 版)进行分析。采用 RoB-2 工具对研究的方法学质量进行了评估。分析结果显示,更年期症状(SMD:-0.49,95 % CI:-1.13 至 0.16,Z = 1.47,P = 0.14)、身体部分(MD:-1.10,95 % CI:-4.22 至 2.01, Z = 0.70, p = 0. 49)和精神部分(MD:0.81, 95 % CI:-6.73 to 8.35, Z = 0.21, p = 0.83),但抑郁水平存在显著差异(SMD:-0.结论根据分析结果,大豆异黄酮对更年期症状(血管运动、社会心理、身体、性和泌尿生殖系统不适)和更年期妇女的生活质量没有影响,但能降低抑郁水平。所纳入的研究存在较高的利益冲突风险:CRD420234479700。
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引用次数: 0
A patient-designed integrative oncology intervention for stage IV locally recurrent rectal cancer: A case report 针对 IV 期局部复发直肠癌的患者设计的综合肿瘤学干预:病例报告。
IF 1.9 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-05-21 DOI: 10.1016/j.explore.2024.05.002
Julia M. Hush , Daniel Steffens , Michael J. Solomon

Introduction

Stage IV colorectal cancer is a highly challenging condition to treat, with 5-year survival rates of 13% in Australia, improving to 40% for those patients with locally recurrent rectal cancer who are suitable for total neoadjuvant therapy and pelvic exenterative surgery. This study reports a unique case of a patient with Stage IV locally recurrent rectal cancer (LRRC), who designed and implemented a holistic integrative oncology intervention.

Case presentation

The patient was 59-years-old when diagnosed with Stage IV locally recurrent rectal cancer, and referred to a highly specialised centre for colorectal cancer care at a tertiary teaching hospital in Sydney, Australia. Treatment included chemo/radiotherapy, liver resection and posterior pelvic exenteration surgery. The patient's background as a health researcher and clinician optimised her ability to design and implement an integrative oncology model of care, including yoga, mindfulness, Buddhist meditation and study, social connection, exercise, psychotherapeutic and nutritional support. This paper describes these mind-body practices and lifestyle modifications and outlines her experiences and outcomes at each stage of her extensive and radical treatment.

Conclusion

This case provides a unique perspective into how the integration of mind-body practices and lifestyle modifications with conventional treatment can support those living with colorectal cancer.

简介IV期结直肠癌是一种极具治疗挑战性的疾病,在澳大利亚,5年生存率仅为13%,而对于适合接受全新药辅助治疗和盆腔肠外手术的局部复发直肠癌患者,5年生存率可提高至40%。本研究报告了一例独特的 IV 期局部复发直肠癌(LRRC)患者的病例,该患者设计并实施了整体综合肿瘤学干预:患者被诊断为局部复发直肠癌 IV 期时 59 岁,并被转诊至澳大利亚悉尼一家三级教学医院的结直肠癌高度专业化治疗中心。治疗包括化疗/放疗、肝脏切除和后盆腔开腹手术。患者的健康研究员和临床医生背景使她有能力设计并实施一种综合肿瘤治疗模式,包括瑜伽、正念、佛教冥想和学习、社会联系、运动、心理治疗和营养支持。本文介绍了这些身心练习和生活方式调整,并概述了她在广泛而彻底的治疗过程中每个阶段的经历和结果:本病例提供了一个独特的视角,让我们了解如何将身心疗法和生活方式调整与常规治疗相结合,为结肠直肠癌患者提供支持。
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引用次数: 0
RANGATAHI MĀORI AND THE WHĀNAU CHOCOLATE BOX: Rangatahi wellbeing in whānau contexts rangatahi māori and the whānau chocolate box:毛利人和毛利人巧克力盒:毛利人的福祉
IF 1.9 4区 医学 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE Pub Date : 2024-05-18 DOI: 10.1016/j.explore.2024.05.005
Te Maringi Mai o Hawaiiki ((Te Arawa)) , Jade Le Grice ((Te Rarawa, Ngāpuhi)) , Logan Hamley ((Ngāti Rangi)) , Cinnamon Lindsay Latimer ((Ngāpuhi, Ngāti Porou)) , Shiloh Groot ((Ngāti Uenukukōpako, Ngāti Pikiao)) , Ashlea Gillon ((Ngāti Awa, Ngāpuhi, Ngāiterangi)) , Lara Greaves ((Ngāpuhi)) , Terryann C. Clark ((Ngāti Whātua, Ngāti Wai, Ngāpuhi))

Whānau (Māori understandings of family) are comprised of unique and vital relationships that support and scaffold rangatahi (youth) wellbeing, yet are often reduced to nuclear family structures within individualised notions of wellbeing. While rangatahi contend with racialised discourses in a colonial socio-cultural context, their whānau can be an important site for mitigating these challenges, supporting rangatahi agency and wellbeing. This article explores how whānau practices inform rangatahi wellbeing, drawing upon photo-projects and interviews with 51 rangatahi and their whānau. Interviews were thematically analysed, informing four themes that drew on Māori (the Indigenous people of Aotearoa) concepts and whakataukī: te haerenga whakamua, kotahitanga, he toa takitini and tātai hono. These themes speak to the significance of vitalising relationships between rangatahi, their whānau and beyond. We outline a strengths-based activity with rangatahi and their whānau, identifying and drawing from the delightful array of whānau relationships, qualities and characteristics that may be likened to a ‘whānau chocolate box’ for rangatahi to derive influence, systems of support and inspiration for future identities and inspiration.

Whānau(毛利人对家庭的理解)是由独特而重要的关系组成的,这些关系支持并支撑着rangatahi(青年)的福祉,但在个人化的福祉概念中,这些关系往往被简化为核心家庭结构。在殖民地社会文化背景下,rangatahi(青少年)与种族化的言论作斗争,而他们的 "家庭"(whānau)则是缓解这些挑战、支持rangatahi(青少年)的能动性和福祉的重要场所。本文通过照片项目和对 51 名 "牧民 "及其 "牧民 "的访谈,探讨了 "牧民 "的做法如何影响 "牧民 "的福祉。对访谈内容进行了专题分析,并根据毛利人(奥特亚罗瓦土著人)的概念和 "whakataukī "提出了四个主题:te haerenga whakamua、kotahitanga、he toa takitini 和 tātai hono。这些主题说明了在 "牧民"、他们的 "牧民 "和其他方面之间建立重要关系的重要性。我们概述了一项以优势为基础的活动,该活动涉及 "长老 "和他们的 "长老",确定并从 "长老 "关系、品质和特征的令人愉快的系列中汲取营养,这些品质和特征可被比作 "长老巧克力盒",供 "长老 "汲取影响、支持系统和灵感,以促进未来的身份和灵感。
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引用次数: 0
Matters of Note 注意事项
IF 2.4 4区 医学 Q1 Health Professions Pub Date : 2024-05-17 DOI: 10.1016/j.explore.2024.05.006
Angie Lillehei
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引用次数: 0
Consciousness, authoritarianism, and political violence 意识、专制主义和政治暴力
IF 2.4 4区 医学 Q1 Health Professions Pub Date : 2024-05-17 DOI: 10.1016/j.explore.2024.05.007
Stephan A. Schwartz
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引用次数: 0
The effects of electronic cigarette inhalation on immune responses: Perspectives from animal model studies 吸入电子烟对免疫反应的影响:动物模型研究的视角
IF 2.4 4区 医学 Q1 Health Professions Pub Date : 2024-05-17 DOI: 10.1016/j.explore.2024.05.008
Kelly Naranjo , Christina Awada , Judith T. Zelikoff
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引用次数: 0
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Explore-The Journal of Science and Healing
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