Pub Date : 2025-07-12DOI: 10.1016/j.explore.2025.103215
Harri Hemilä , Elizabeth Chalker
{"title":"Misleading summary of the Cochrane review on zinc for the common cold (2024)","authors":"Harri Hemilä , Elizabeth Chalker","doi":"10.1016/j.explore.2025.103215","DOIUrl":"10.1016/j.explore.2025.103215","url":null,"abstract":"","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"21 5","pages":"Article 103215"},"PeriodicalIF":1.9,"publicationDate":"2025-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144656208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Online mindfulness may be an effective non-pharmacological mental health intervention.
Objective
To evaluate the effectiveness of an online mindfulness platform in ameliorating anxiety, depression, and stress in patients with chronic diseases.
Methods
In this randomized controlled study, 97 patients were enrolled and randomly assigned to either the online intervention group (N = 47) or the control group (N = 50). Anxiety, depression, and stress levels were assessed at baseline, 4 weeks, and 8 weeks after the intervention.
Results
The baseline scores of anxiety, depression, and stress between the control and experiment groups were comparable. Online mindfulness intervention significantly reduced anxiety scores at Week 4 and Week 8 (both P < 0.001). In addition, online mindfulness intervention significantly lowered both depression scores and stress levels at Week 8 (both P ≤ 0.002), but not at Week 4.
Conclusion
Online mindfulness interventions effectively alleviate anxiety, depression, and stress in patients with chronic diseases. Future qualitative research is recommended to further explore the mechanisms of change at the psychological level.
{"title":"Effect of online mindfulness intervention on anxiety, depression, and stress in patients with chronic diseases","authors":"Ying-Ju Chen , Chiu-Hsiang Lee , Chia-Jung Hsieh , Pei-Hung Liao , Yu-Da Chen , Kuei-Ru Chou , Shu-Liu Guo , Li-Fang Chang , Tso-Ying Lee","doi":"10.1016/j.explore.2025.103214","DOIUrl":"10.1016/j.explore.2025.103214","url":null,"abstract":"<div><h3>Background</h3><div>Online mindfulness may be an effective non-pharmacological mental health intervention.</div></div><div><h3>Objective</h3><div>To evaluate the effectiveness of an online mindfulness platform in ameliorating anxiety, depression, and stress in patients with chronic diseases.</div></div><div><h3>Methods</h3><div>In this randomized controlled study, 97 patients were enrolled and randomly assigned to either the online intervention group (<em>N</em> = 47) or the control group (<em>N</em> = 50). Anxiety, depression, and stress levels were assessed at baseline, 4 weeks, and 8 weeks after the intervention.</div></div><div><h3>Results</h3><div>The baseline scores of anxiety, depression, and stress between the control and experiment groups were comparable. Online mindfulness intervention significantly reduced anxiety scores at Week 4 and Week 8 (both <em>P</em> < 0.001). In addition, online mindfulness intervention significantly lowered both depression scores and stress levels at Week 8 (both <em>P</em> ≤ 0.002), but not at Week 4.</div></div><div><h3>Conclusion</h3><div>Online mindfulness interventions effectively alleviate anxiety, depression, and stress in patients with chronic diseases. Future qualitative research is recommended to further explore the mechanisms of change at the psychological level.</div></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"21 5","pages":"Article 103214"},"PeriodicalIF":1.9,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144656209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-07DOI: 10.1016/j.explore.2025.103210
Natasha Tassell-Matamua
{"title":"Environmental woes and the role of Indigenous knowledges","authors":"Natasha Tassell-Matamua","doi":"10.1016/j.explore.2025.103210","DOIUrl":"10.1016/j.explore.2025.103210","url":null,"abstract":"","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"21 5","pages":"Article 103210"},"PeriodicalIF":1.9,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144605315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-07DOI: 10.1016/j.explore.2025.103213
Himanshu Shekhar , Dr. Parth Aphale , Shashank Dokania
{"title":"Corrigendum to “Constructive appraisal of “retrospective case control study of microcurrent therapy in autism spectrum disorder: Behavioral outcomes and dose-response analysis”","authors":"Himanshu Shekhar , Dr. Parth Aphale , Shashank Dokania","doi":"10.1016/j.explore.2025.103213","DOIUrl":"10.1016/j.explore.2025.103213","url":null,"abstract":"","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"21 5","pages":"Article 103213"},"PeriodicalIF":1.9,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144605316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-07DOI: 10.1016/j.explore.2025.103206
Stephan A. Schwartz
{"title":"Consciousness, the decline of American healthcare and its dramatic effect on women","authors":"Stephan A. Schwartz","doi":"10.1016/j.explore.2025.103206","DOIUrl":"10.1016/j.explore.2025.103206","url":null,"abstract":"","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"21 5","pages":"Article 103206"},"PeriodicalIF":1.9,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144696513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-07DOI: 10.1016/j.explore.2025.103207
Angie Lillehei
{"title":"Circadian Rhythm Syndrome and mortality risk","authors":"Angie Lillehei","doi":"10.1016/j.explore.2025.103207","DOIUrl":"10.1016/j.explore.2025.103207","url":null,"abstract":"","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"21 5","pages":"Article 103207"},"PeriodicalIF":1.9,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144656207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-02DOI: 10.1016/j.explore.2025.103209
Heba Hussein , L. Susan Wieland
{"title":"Vitamin D supplementation for women during pregnancy: summary of a Cochrane review","authors":"Heba Hussein , L. Susan Wieland","doi":"10.1016/j.explore.2025.103209","DOIUrl":"10.1016/j.explore.2025.103209","url":null,"abstract":"","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"21 5","pages":"Article 103209"},"PeriodicalIF":1.9,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144587403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Integrative medicine is a whole-person approach that combines conventional and complementary approaches to address physical, emotional, and spiritual well-being while facing challenges such as fragmented healthcare systems, lack of interoperability, and poor data management. The metaverse is a virtual space that combines physical and virtual reality, allowing real-time interaction with digital avatars. Blockchain is a decentralized and secure ledger for recording transactional data. By leveraging metaverse and blockchain technology, healthcare providers can collaborate and share data on a secure and transparent platform, addressing the challenges faced by integrative medicine. This paper discusses the potential impact of integrating the metaverse and blockchain technology in integrative medicine. It provides a comprehensive insight into the possible applications of this integration, including patient education, therapy delivery, and medical training. Its undeniable challenges and promising prospects are also addressed.
{"title":"Application of metaverse and blockchain technology in integrative medicine","authors":"Babak Daneshfard , Mahboubeh Sadat Fateminasab , Alireza Asghari","doi":"10.1016/j.explore.2025.103212","DOIUrl":"10.1016/j.explore.2025.103212","url":null,"abstract":"<div><div>Integrative medicine is a whole-person approach that combines conventional and complementary approaches to address physical, emotional, and spiritual well-being while facing challenges such as fragmented healthcare systems, lack of interoperability, and poor data management. The metaverse is a virtual space that combines physical and virtual reality, allowing real-time interaction with digital avatars. Blockchain is a decentralized and secure ledger for recording transactional data. By leveraging metaverse and blockchain technology, healthcare providers can collaborate and share data on a secure and transparent platform, addressing the challenges faced by integrative medicine. This paper discusses the potential impact of integrating the metaverse and blockchain technology in integrative medicine. It provides a comprehensive insight into the possible applications of this integration, including patient education, therapy delivery, and medical training. Its undeniable challenges and promising prospects are also addressed.</div></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"21 5","pages":"Article 103212"},"PeriodicalIF":1.9,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144581409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-01DOI: 10.1016/j.explore.2025.103201
Betül BAL , Nagihan KÖROĞLU-KABA , Havva ÖZTÜRK , Yeter KURT , Aysel ÖZSABAN
The aim of this study was to determine the effect of laughter yoga on hemodialysis patients' disease acceptance, treatment adherence and comfort levels. This randomized controlled study was conducted with 42 patients (experimental group=21, control group=21) who were treated in the hemodialysis unit. Hemodialysis patients in the experimental group received 12 sessions of laughter yoga for four weeks, three days a week. Data were collected using Patient Information Form, Disease Acceptance Scale, End-Stage Renal Disease Adherence Questionnaire, and Hemodialysis Comfort Scale. A significant difference was found between the disease acceptance scale (t(41) = 4.39, p < 0.001, d = 1.364), end-stage renal failure adaptation scale (t(41) = 2.69, p = 0.010, d = 0.830) and hemodialysis comfort scale (t(41) = 5.58, p = 0.010, d = 1.710) of hemodialysis patients who underwent laughter yoga. In addition for the Disease Acceptance Scale, the SD of the pre-test scores was 7.51. Accordingly, the MCID thresholds were calculated as 3.75 (0.5 SD), 3.11 (1 SEM), and 6.09 (1.96 SEM). For the End-Stage Renal Disease Adherence Questionnaire, the SD was 178.79, and the MCID was calculated as 89.40 (0.5 SD), 63.47 (1 SEM), and 124.39 (1.96 SEM). For the Hemodialysis Comfort Scale, the SD was 6.43, resulting in MCID estimates of 3.21 (0.5 SD), 2.01 (1 SEM), and 3.94 (1.96 SEM). Laughter yoga practiced during hemodialysis increased acceptance of the disease, adherence to treatment, and comfort (p < 0.05). In contrast, no statistically significant difference was found in the control group (p > 0.05). Increasing hemodialysis patients' acceptance of the disease, adherence to treatment, and comfort levels ensure the successful continuation of the disease management process. The practice of laughter yoga in clinics during hemodialysis sessions is recommended to increase disease acceptance, adherence to treatment and comfort levels.
本研究的目的是确定笑瑜伽对血液透析患者疾病接受度、治疗依从性和舒适度的影响。本研究采用随机对照方法，选取42例在血透病房接受治疗的患者，实验组21例，对照组21例。血液透析患者在实验组接受12次笑声瑜伽，为期四周，每周三天。采用患者信息表、疾病接受度量表、终末期肾病依从性问卷和血液透析舒适度量表收集数据。疾病接受度量表(t(41) = 4.39, p <；0.001, d = 1.364)、终末期肾功能衰竭适应量表（t(41) = 2.69, p = 0.010, d = 0.830）和血液透析舒适量表（t(41) = 5.58, p = 0.010, d = 1.710）。另外，疾病接受度量表的前测分数标准差为7.51。据此，MCID阈值分别为3.75 （0.5 SD）、3.11 （1 SEM）和6.09 （1.96 SEM）。终末期肾病依从性问卷的SD为178.79，MCID分别为89.40 （0.5 SD）、63.47 （1 SEM）和124.39 （1.96 SEM）。对于血液透析舒适量表，SD为6.43，导致MCID估计值为3.21 (0.5 SD), 2.01 （1 SEM）和3.94 （1.96 SEM）。在血液透析期间练习笑声瑜伽增加了对疾病的接受度，对治疗的依从性和舒适度(p <；0.05)。相比之下，对照组无统计学差异(p >；0.05)。增加血液透析患者对疾病的接受程度、对治疗的依从性和舒适度确保了疾病管理过程的成功延续。建议在诊所血液透析期间练习笑瑜伽，以增加疾病的接受度，坚持治疗和舒适度。
{"title":"The effect of laughter yoga on disease acceptance, treatment adherence and comfort in hemodialysis patients: A randomized controlled study","authors":"Betül BAL , Nagihan KÖROĞLU-KABA , Havva ÖZTÜRK , Yeter KURT , Aysel ÖZSABAN","doi":"10.1016/j.explore.2025.103201","DOIUrl":"10.1016/j.explore.2025.103201","url":null,"abstract":"<div><div>The aim of this study was to determine the effect of laughter yoga on hemodialysis patients' disease acceptance, treatment adherence and comfort levels. This randomized controlled study was conducted with 42 patients (experimental group=21, control group=21) who were treated in the hemodialysis unit. Hemodialysis patients in the experimental group received 12 sessions of laughter yoga for four weeks, three days a week. Data were collected using Patient Information Form, Disease Acceptance Scale, End-Stage Renal Disease Adherence Questionnaire, and Hemodialysis Comfort Scale. A significant difference was found between the disease acceptance scale (t(41) = 4.39, <em>p</em> < 0.001, <em>d</em> = 1.364), end-stage renal failure adaptation scale (t(41) = 2.69, <em>p</em> = 0.010, <em>d</em> = 0.830) and hemodialysis comfort scale (t(41) = 5.58, <em>p</em> = 0.010, <em>d</em> = 1.710) of hemodialysis patients who underwent laughter yoga. In addition for the Disease Acceptance Scale, the SD of the pre-test scores was 7.51. Accordingly, the MCID thresholds were calculated as 3.75 (0.5 SD), 3.11 (1 SEM), and 6.09 (1.96 SEM). For the End-Stage Renal Disease Adherence Questionnaire, the SD was 178.79, and the MCID was calculated as 89.40 (0.5 SD), 63.47 (1 SEM), and 124.39 (1.96 SEM). For the Hemodialysis Comfort Scale, the SD was 6.43, resulting in MCID estimates of 3.21 (0.5 SD), 2.01 (1 SEM), and 3.94 (1.96 SEM). Laughter yoga practiced during hemodialysis increased acceptance of the disease, adherence to treatment, and comfort (<em>p</em> < 0.05). In contrast, no statistically significant difference was found in the control group (p > 0.05). Increasing hemodialysis patients' acceptance of the disease, adherence to treatment, and comfort levels ensure the successful continuation of the disease management process. The practice of laughter yoga in clinics during hemodialysis sessions is recommended to increase disease acceptance, adherence to treatment and comfort levels.</div></div>","PeriodicalId":50459,"journal":{"name":"Explore-The Journal of Science and Healing","volume":"21 4","pages":"Article 103201"},"PeriodicalIF":1.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144589094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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