Bowen Tang, Tao Tan, Yi Huang, Mi Zhang, Mengqing Li, Xiaocan Lei, Weihua Nong
Background : Polycystic ovary syndrome (PCOS) stands as one of the most prevalent endocrine disorders affecting women of reproductive age. Despite being recognized for decades, numerous unresolved issues persist regarding its impact on reproductive medicine. Metformin, a widely utilized drug in clinical practice for PCOS management, has attracted researchers’ attention due to its pharmacological mechanism and novel drug combination methods. Methods : This study employs bibliometric analysis to comprehensively examine the research progress in this field. The statistical source for this paper is Web of Science, covering the entire timespan. Utilizing various tools such as Web of Science, VOSviewer, and CiteSpace for analysis, the focus is on countries, institutions, authors, journals, and keywords. Data encompass the total number of papers published, total citations, and the average number of citations per paper. Results : Our analysis uncovered 2817 papers within the statistical range, with both paper count and citations exhibiting a rising trend over the years. The United States, China, and the United Kingdom emerged as influential countries in this field. Primary research areas include molecular biology, immunology, and clinical medicine. While China has made significant progress in recent years, there is room for improvement in the average number of citations per article, highlighting the importance of emphasizing article quality. Conclusions : The United States has spearheaded research in this field, potentially owing to support from domestic universities. Nevertheless, the notable contribution of Chinese scientists cannot be overlooked. Among universities, the most prolific are the Federal University of Virginia from United States and Fudan University from China. Notably, Glueck CJ is identified as the most productive researcher in this field. Fertility and Sterility, ranking first globally in terms of both article count and citations, emerges as the most popular journal in this field.
背景：多囊卵巢综合征（PCOS）是影响育龄妇女最普遍的内分泌疾病之一。尽管多囊卵巢综合征已被公认数十年，但其对生殖医学的影响仍存在许多悬而未决的问题。二甲双胍是临床上广泛用于治疗多囊卵巢综合征的药物，因其药理机制和新颖的联合用药方法而备受研究人员关注。方法：本研究采用文献计量学分析方法，全面考察该领域的研究进展。本文的统计来源是 Web of Science，涵盖了整个时间跨度。利用 Web of Science、VOSviewer 和 CiteSpace 等多种工具进行分析，重点关注国家、机构、作者、期刊和关键词。数据包括发表论文的总数、总引用次数和每篇论文的平均引用次数。结果：我们的分析在统计范围内发现了 2817 篇论文，论文数量和引用次数均呈现逐年上升趋势。美国、中国和英国成为该领域有影响力的国家。主要研究领域包括分子生物学、免疫学和临床医学。虽然中国近年来取得了长足进步，但每篇文章的平均被引次数仍有待提高，这凸显了重视文章质量的重要性。结论 ：美国在这一领域的研究处于领先地位，这可能得益于国内大学的支持。然而，中国科学家的突出贡献也不容忽视。在众多大学中，美国弗吉尼亚联邦大学和中国复旦大学的研究成果最为丰富。值得注意的是，Glueck CJ 被认为是该领域最有成果的研究人员。生育与不育》在文章数量和引用次数方面均居全球首位，成为该领域最受欢迎的期刊。
{"title":"A Bibliometric Analysis of Global Research Trends in Polycystic Ovary Syndrome and Metformin","authors":"Bowen Tang, Tao Tan, Yi Huang, Mi Zhang, Mengqing Li, Xiaocan Lei, Weihua Nong","doi":"10.31083/j.ceog5104086","DOIUrl":"https://doi.org/10.31083/j.ceog5104086","url":null,"abstract":"Background : Polycystic ovary syndrome (PCOS) stands as one of the most prevalent endocrine disorders affecting women of reproductive age. Despite being recognized for decades, numerous unresolved issues persist regarding its impact on reproductive medicine. Metformin, a widely utilized drug in clinical practice for PCOS management, has attracted researchers’ attention due to its pharmacological mechanism and novel drug combination methods. Methods : This study employs bibliometric analysis to comprehensively examine the research progress in this field. The statistical source for this paper is Web of Science, covering the entire timespan. Utilizing various tools such as Web of Science, VOSviewer, and CiteSpace for analysis, the focus is on countries, institutions, authors, journals, and keywords. Data encompass the total number of papers published, total citations, and the average number of citations per paper. Results : Our analysis uncovered 2817 papers within the statistical range, with both paper count and citations exhibiting a rising trend over the years. The United States, China, and the United Kingdom emerged as influential countries in this field. Primary research areas include molecular biology, immunology, and clinical medicine. While China has made significant progress in recent years, there is room for improvement in the average number of citations per article, highlighting the importance of emphasizing article quality. Conclusions : The United States has spearheaded research in this field, potentially owing to support from domestic universities. Nevertheless, the notable contribution of Chinese scientists cannot be overlooked. Among universities, the most prolific are the Federal University of Virginia from United States and Fudan University from China. Notably, Glueck CJ is identified as the most productive researcher in this field. Fertility and Sterility, ranking first globally in terms of both article count and citations, emerges as the most popular journal in this field.","PeriodicalId":505527,"journal":{"name":"Clinical and Experimental Obstetrics & Gynecology","volume":"12 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140374168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xi Luo, Zhenlin He, Rui Ma, Na Lin, Lei Li, Yunxiu Li, Yang Ke, Xia Meng, Ze Wu
Objective : We aimed to explore the multifaceted etiology of recurrent implantation failure (RIF) and evaluate the efficacy of various management strategies, with a focus on refining examination protocols and treatment pathways to improve implantation success rates in patients undergoing in vitro fertilization-embryo transfer. Mechanism : The development of RIF can be attributed to a complex causal network of factors. Chromosomal anomalies, such as aneuploidies, directly impact the genetic viability of embryos. Immune system dysregulation, marked by the presence of autoantibodies, disrupts the normal immunological tolerance required for successful implantation. Endocrine disruptions interfere with the hormonal balance essential for preparing the endometrium for implantation. Anatomical irregularities in the female reproductive tract can physically impede the embryo’s ability to implant. Lifestyle factors, including diet, stress, and environmental exposures, influence both male and female reproductive health, affecting gamete quality and implantation potential. These diverse factors interact in a multifaceted manner, making a personalized diagnostic and therapeutic approach essential for addressing the specific causes in each case of RIF. Findings in brief : The review synthesizes current understanding of RIF’s etiology, highlighting the need for innovative interventions and adjustments in clinical practice. It emphasizes the significance of a highly personalized approach in managing RIF, incorporating refined examination protocols and tailor-made treatment pathways to address the unique combination of factors present in each case. Conclusions : Effective management of RIF requires innovative interventions and a shift in clinical practice towards personalized care. Identifying gaps in the current understanding of RIF points towards a clear direction for future research, aimed at refining treatment protocols and improving outcomes for patients. This contributes significantly to the broader field of reproductive medicine, aiming to alleviate the clinical and psychological burdens of RIF.
{"title":"Narrative Review of Multifaceted Approaches to Managing Recurrent Implantation Failure: Insights and Innovations","authors":"Xi Luo, Zhenlin He, Rui Ma, Na Lin, Lei Li, Yunxiu Li, Yang Ke, Xia Meng, Ze Wu","doi":"10.31083/j.ceog5104087","DOIUrl":"https://doi.org/10.31083/j.ceog5104087","url":null,"abstract":"Objective : We aimed to explore the multifaceted etiology of recurrent implantation failure (RIF) and evaluate the efficacy of various management strategies, with a focus on refining examination protocols and treatment pathways to improve implantation success rates in patients undergoing in vitro fertilization-embryo transfer. Mechanism : The development of RIF can be attributed to a complex causal network of factors. Chromosomal anomalies, such as aneuploidies, directly impact the genetic viability of embryos. Immune system dysregulation, marked by the presence of autoantibodies, disrupts the normal immunological tolerance required for successful implantation. Endocrine disruptions interfere with the hormonal balance essential for preparing the endometrium for implantation. Anatomical irregularities in the female reproductive tract can physically impede the embryo’s ability to implant. Lifestyle factors, including diet, stress, and environmental exposures, influence both male and female reproductive health, affecting gamete quality and implantation potential. These diverse factors interact in a multifaceted manner, making a personalized diagnostic and therapeutic approach essential for addressing the specific causes in each case of RIF. Findings in brief : The review synthesizes current understanding of RIF’s etiology, highlighting the need for innovative interventions and adjustments in clinical practice. It emphasizes the significance of a highly personalized approach in managing RIF, incorporating refined examination protocols and tailor-made treatment pathways to address the unique combination of factors present in each case. Conclusions : Effective management of RIF requires innovative interventions and a shift in clinical practice towards personalized care. Identifying gaps in the current understanding of RIF points towards a clear direction for future research, aimed at refining treatment protocols and improving outcomes for patients. This contributes significantly to the broader field of reproductive medicine, aiming to alleviate the clinical and psychological burdens of RIF.","PeriodicalId":505527,"journal":{"name":"Clinical and Experimental Obstetrics & Gynecology","volume":"98 31","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140377447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background : Toevaluate thechemotherapy toxicityof 5-fluorouracil(5-FU) inthe treatment ofinvasive moles. Methods : Weconducted a retrospective study of therapeutic satisfaction, recurrence, and toxicity in 17 patients treated with 5-FU in the Zhuzhou Central Hospital, from 2015 to 2020. Results : After a single-agent 5-FU treatment a complete remission of low-risk invasive moles was observed, and remission of high-risk invasive moles reached rates of 76.5%. After 4–5 chemotherapy cycles, 5-FU reduced serum human chorionic gonadotropin (hCG) to normal levels in invasive moles. Furthermore, a toxicity assessment revealed that 5-FU chemotherapy has low toxicity and is generally acceptable for patients. Conclusions : 5-FU offers high efficacy in both low-risk and high-risk invasive moles, with low chemotherapy toxicity.
{"title":"Analysis of the Efficacy of 5-Fluorouracil in the Treatment of Invasive Moles","authors":"Chunhua Liu, Peilin Ouyang, Yin Tao, Mingyu Xie","doi":"10.31083/j.ceog5104083","DOIUrl":"https://doi.org/10.31083/j.ceog5104083","url":null,"abstract":"Background : Toevaluate thechemotherapy toxicityof 5-fluorouracil(5-FU) inthe treatment ofinvasive moles. Methods : Weconducted a retrospective study of therapeutic satisfaction, recurrence, and toxicity in 17 patients treated with 5-FU in the Zhuzhou Central Hospital, from 2015 to 2020. Results : After a single-agent 5-FU treatment a complete remission of low-risk invasive moles was observed, and remission of high-risk invasive moles reached rates of 76.5%. After 4–5 chemotherapy cycles, 5-FU reduced serum human chorionic gonadotropin (hCG) to normal levels in invasive moles. Furthermore, a toxicity assessment revealed that 5-FU chemotherapy has low toxicity and is generally acceptable for patients. Conclusions : 5-FU offers high efficacy in both low-risk and high-risk invasive moles, with low chemotherapy toxicity.","PeriodicalId":505527,"journal":{"name":"Clinical and Experimental Obstetrics & Gynecology","volume":"105 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140380711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Explanatory Model of Self-Efficacy for Cervical Cancer Screening","authors":"Angela-Cristina Yanez Corrales, Maria-Teresa Urrutia, Oslando Padilla","doi":"10.31083/j.ceog5104084","DOIUrl":"https://doi.org/10.31083/j.ceog5104084","url":null,"abstract":"","PeriodicalId":505527,"journal":{"name":"Clinical and Experimental Obstetrics & Gynecology","volume":"44 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140378520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Huanhuan Wang, J. Meng, Guoqiang Dong, Lijing Zhu, Zhengyang Zhou, Yuan Jiang, Li Zhu
Background : To explore the feasibility of radiomic models using different magnetic resonance imaging (MRI) sequences combined with clinical information in evaluating the status of lymphovascular space invasion (LVSI) in cervical cancer. Methods : One hundred one cervical cancer patients were included from January 2018 to December 2020. All patients underwent 3.0T MRI examination including T2 weighted imaging (T2WI), diffusion weighted imaging (DWI) and contrast-enhanced T1 weighted imaging (T1WI + C) enhanced sequences. Age, preoperative squamous cell carcinoma (SCC) associated antigen value and the depth of muscular invasion were collected. The 101 patients were divided into training set and validation set. Three different models were developed using T2WI, DWI and T1WI + C parameters respectively. One model was developed combining the three different sequences. The diagnostic performance of each model was compared via receiver operating characteristic curve analysis. Results : Forty-eight cases were pathologically confirmed with lymphovascular space invasion. The average SCC value of the LVSI positive group (10.82 ± 20.11 ng/mL) was higher than that of the negative group (6.71 ± 14.45 ng/mL), however there was no significant statistical difference between the two groups. No clinical or traditional imaging features were selected by spearman correlation analysis. Among the corresponding radiomic models, the machine learning model based on multi-modality showed the best diagnostic efficiency in the evaluation of LVSI (receiver operating characteristic (ROC) curve of multimodal radiomics in the training set (area under the ROC curve (AUC) = 0.990 (0.975–0.999)) and in the validation set (AUC = 0.832 (0.693–0.971)). Conclusions : The diagnostic efficacy of radiomics is superior to conventional MRI parameters and clinical parameters. The radiomics-based machine learning model can help improve accuracy for the preoperative evaluation of LVSI in cervical cancer.
{"title":"Multi-Parametric MRI Combined with Radiomics for the Evaluation of Lymphovascular Space Invasion in Cervical Cancer","authors":"Huanhuan Wang, J. Meng, Guoqiang Dong, Lijing Zhu, Zhengyang Zhou, Yuan Jiang, Li Zhu","doi":"10.31083/j.ceog5104081","DOIUrl":"https://doi.org/10.31083/j.ceog5104081","url":null,"abstract":"Background : To explore the feasibility of radiomic models using different magnetic resonance imaging (MRI) sequences combined with clinical information in evaluating the status of lymphovascular space invasion (LVSI) in cervical cancer. Methods : One hundred one cervical cancer patients were included from January 2018 to December 2020. All patients underwent 3.0T MRI examination including T2 weighted imaging (T2WI), diffusion weighted imaging (DWI) and contrast-enhanced T1 weighted imaging (T1WI + C) enhanced sequences. Age, preoperative squamous cell carcinoma (SCC) associated antigen value and the depth of muscular invasion were collected. The 101 patients were divided into training set and validation set. Three different models were developed using T2WI, DWI and T1WI + C parameters respectively. One model was developed combining the three different sequences. The diagnostic performance of each model was compared via receiver operating characteristic curve analysis. Results : Forty-eight cases were pathologically confirmed with lymphovascular space invasion. The average SCC value of the LVSI positive group (10.82 ± 20.11 ng/mL) was higher than that of the negative group (6.71 ± 14.45 ng/mL), however there was no significant statistical difference between the two groups. No clinical or traditional imaging features were selected by spearman correlation analysis. Among the corresponding radiomic models, the machine learning model based on multi-modality showed the best diagnostic efficiency in the evaluation of LVSI (receiver operating characteristic (ROC) curve of multimodal radiomics in the training set (area under the ROC curve (AUC) = 0.990 (0.975–0.999)) and in the validation set (AUC = 0.832 (0.693–0.971)). Conclusions : The diagnostic efficacy of radiomics is superior to conventional MRI parameters and clinical parameters. The radiomics-based machine learning model can help improve accuracy for the preoperative evaluation of LVSI in cervical cancer.","PeriodicalId":505527,"journal":{"name":"Clinical and Experimental Obstetrics & Gynecology","volume":" 792","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140382704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Susana Blanco-López, Laura Peteiro-Mahia, Rocío Navas-Arrebola, Noelia López-Castiñeira, Sonia Pértega-Díaz, T. Seoane-Pillado
Background : The object is to analyze the influence of the nocturnal period and lunar phases on the frequency of obstetrical events in pregnant women. Methods : This was a retrospective, transversal observational study of 1409 births in a hospital from northwest Spain ( α = 0.05; precision = ± 2.65%). A review of patients’ clinical records was performed recording the following data: labor onset type, date of last menstrual period, parity, gestational age, duration of pre-labor and labor, type of delivery, the hour, work shift, and lunar phase pattern of events. Statistical evaluation included descriptive and inferential analysis. Results : Labor was spontaneous in 58.3% of all cases; spontaneous deliveries accounted for 54.2% of the total and 19.2% were instrumental. In the cases of spontaneous labor onset, 48.5% began during the nocturnal period. The early labor phase was less than 6 hours in 62.7% of cases (44.8% during the full moon phase). During the nocturnal period, rupture of membranes and dilation periods of less than 3 hours were more common, with 32% of spontaneous membrane rupture occurring during a full moon. A significant dependence was observed between the labor type and nocturnal period, as 40.8% of all spontaneous births, 36.2% of instrumental births and 46.9% of emergency cesarean sections occurred during the night shift. Furthermore, 66.3% of precipitous deliveries ( < 3 hours) took place during this period. Conclusions : The nocturnal period is related to a higher number of spontaneous rupture of the membranes, non-intervention in the onset of labor, shorter early labor phases, faster deliveries, spontaneous births and emergency caesarean sections. A higher frequency of spontaneous rupture of the membranes, a full labor, early labor phases of less than 3 hours and emergency caesarean sections was observed during full moon phases.
{"title":"Current Experience with Obstetrical Events: Characteristics and the Effects of Nocturnal Periods","authors":"Susana Blanco-López, Laura Peteiro-Mahia, Rocío Navas-Arrebola, Noelia López-Castiñeira, Sonia Pértega-Díaz, T. Seoane-Pillado","doi":"10.31083/j.ceog5104080","DOIUrl":"https://doi.org/10.31083/j.ceog5104080","url":null,"abstract":"Background : The object is to analyze the influence of the nocturnal period and lunar phases on the frequency of obstetrical events in pregnant women. Methods : This was a retrospective, transversal observational study of 1409 births in a hospital from northwest Spain ( α = 0.05; precision = ± 2.65%). A review of patients’ clinical records was performed recording the following data: labor onset type, date of last menstrual period, parity, gestational age, duration of pre-labor and labor, type of delivery, the hour, work shift, and lunar phase pattern of events. Statistical evaluation included descriptive and inferential analysis. Results : Labor was spontaneous in 58.3% of all cases; spontaneous deliveries accounted for 54.2% of the total and 19.2% were instrumental. In the cases of spontaneous labor onset, 48.5% began during the nocturnal period. The early labor phase was less than 6 hours in 62.7% of cases (44.8% during the full moon phase). During the nocturnal period, rupture of membranes and dilation periods of less than 3 hours were more common, with 32% of spontaneous membrane rupture occurring during a full moon. A significant dependence was observed between the labor type and nocturnal period, as 40.8% of all spontaneous births, 36.2% of instrumental births and 46.9% of emergency cesarean sections occurred during the night shift. Furthermore, 66.3% of precipitous deliveries ( < 3 hours) took place during this period. Conclusions : The nocturnal period is related to a higher number of spontaneous rupture of the membranes, non-intervention in the onset of labor, shorter early labor phases, faster deliveries, spontaneous births and emergency caesarean sections. A higher frequency of spontaneous rupture of the membranes, a full labor, early labor phases of less than 3 hours and emergency caesarean sections was observed during full moon phases.","PeriodicalId":505527,"journal":{"name":"Clinical and Experimental Obstetrics & Gynecology","volume":" 73","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140384308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Jenabi, A. Salehi, S. Aghababaei, Salman Khazaei
Background : Hyperemesis gravidarum (HG) is an infrequent and severe occurrence of nausea and/or vomiting during pregnancy, with a prevalence ranging from 0.3% to 2%. Until now, no meta-analytic study has been undertaken to assess the correlation between pre-pregnancy body mass index (BMI) and the likelihood of HG. Consequently, this meta-analysis was carried out to examine the connection between BMI and HG risk. Methods : For this systematic review and meta-analysis, we conducted a thorough search of electronic bibliographic databases such as PubMed, Web of Science, Scopus
{"title":"Pre-Pregnancy Body Mass Index and the Risk of Hyperemesis Gravidarum: A Systematic Review and Meta-Analysis","authors":"E. Jenabi, A. Salehi, S. Aghababaei, Salman Khazaei","doi":"10.31083/j.ceog5104082","DOIUrl":"https://doi.org/10.31083/j.ceog5104082","url":null,"abstract":"Background : Hyperemesis gravidarum (HG) is an infrequent and severe occurrence of nausea and/or vomiting during pregnancy, with a prevalence ranging from 0.3% to 2%. Until now, no meta-analytic study has been undertaken to assess the correlation between pre-pregnancy body mass index (BMI) and the likelihood of HG. Consequently, this meta-analysis was carried out to examine the connection between BMI and HG risk. Methods : For this systematic review and meta-analysis, we conducted a thorough search of electronic bibliographic databases such as PubMed, Web of Science, Scopus","PeriodicalId":505527,"journal":{"name":"Clinical and Experimental Obstetrics & Gynecology","volume":" August","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140383233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Alayed, M. Arafah, W. Alkhamis, Khalid M Akkour, Ghada A. AlMalki, Munerah A. M. Alomari, Lama Alshwairikh, Ahmed Sherif Abdel Hamid
Background : Placental chorangiosis is a response to fetal hypoxia, linked to be associated with maternal/fetal disorders and higher mortality rates. Therefore, this study aimed to explore the association of placental chorangiosis with specific maternal clinical risk factors, as well as its impact on pregnancy outcomes compared to pregnancies with normal placental conditions. Methods : This retrospective case-control study was conducted at King Saud University Medical City (KSUMC) between September 2018 and December 2021. A total of 78 pregnant women were included, and 26 cases of placental chorangiosis were identified and included in the study, which were randomly matched to 52 controls. The demographic data of maternal factors (age, body mass index (BMI), type of gestation, gravidity, and parity) and pregnancy outcomes (abortion, gestation age at delivery, mode of delivery, born alive or not, Appearance, Pulse, Grimace, Activity, and Respiration (APGAR) score at 1 and 5 minutes, birth weight, and mean placental weight) were retrieved from the patient’s medical records, all placental histopathological examination were reviewed. Simple and multiple logistic regression analysis were used, and crude and adjusted odds ratios (ORs) and relative risk (RR) were reported with a 95% confidence interval (95% CI). Results : None of the potential maternal risk factors (age, BMI, type of gestation, gravidity, and parity) were statistically associated with chorangiosis. Chorangiosis, however, exhibit statistically significant associations with an increased number of abortions (RR: 21.59, 95% CI: 1.24– 376.20, p = 0.003), intrauterine fetal death (IUFD; RR: 4.50, 95% CI: 1.53–13.25, p = 0.004), and low neonatal APGAR scores at 5 minutes (RR: 3.31, 95% CI: 1.22–9.01, p = 0.029). Conclusion : Placental chorangiosis is a rare pathological change in the placenta resulting from the interaction of several maternal and fetal disorders. When present, it can serve as an important indicator of chronic fetal hypoxia and predict poor obstetrical outcomes.
{"title":"Placental Chorangiosis: Clinical Risk Factors and Pregnancy Outcomes","authors":"N. Alayed, M. Arafah, W. Alkhamis, Khalid M Akkour, Ghada A. AlMalki, Munerah A. M. Alomari, Lama Alshwairikh, Ahmed Sherif Abdel Hamid","doi":"10.31083/j.ceog5104079","DOIUrl":"https://doi.org/10.31083/j.ceog5104079","url":null,"abstract":"Background : Placental chorangiosis is a response to fetal hypoxia, linked to be associated with maternal/fetal disorders and higher mortality rates. Therefore, this study aimed to explore the association of placental chorangiosis with specific maternal clinical risk factors, as well as its impact on pregnancy outcomes compared to pregnancies with normal placental conditions. Methods : This retrospective case-control study was conducted at King Saud University Medical City (KSUMC) between September 2018 and December 2021. A total of 78 pregnant women were included, and 26 cases of placental chorangiosis were identified and included in the study, which were randomly matched to 52 controls. The demographic data of maternal factors (age, body mass index (BMI), type of gestation, gravidity, and parity) and pregnancy outcomes (abortion, gestation age at delivery, mode of delivery, born alive or not, Appearance, Pulse, Grimace, Activity, and Respiration (APGAR) score at 1 and 5 minutes, birth weight, and mean placental weight) were retrieved from the patient’s medical records, all placental histopathological examination were reviewed. Simple and multiple logistic regression analysis were used, and crude and adjusted odds ratios (ORs) and relative risk (RR) were reported with a 95% confidence interval (95% CI). Results : None of the potential maternal risk factors (age, BMI, type of gestation, gravidity, and parity) were statistically associated with chorangiosis. Chorangiosis, however, exhibit statistically significant associations with an increased number of abortions (RR: 21.59, 95% CI: 1.24– 376.20, p = 0.003), intrauterine fetal death (IUFD; RR: 4.50, 95% CI: 1.53–13.25, p = 0.004), and low neonatal APGAR scores at 5 minutes (RR: 3.31, 95% CI: 1.22–9.01, p = 0.029). Conclusion : Placental chorangiosis is a rare pathological change in the placenta resulting from the interaction of several maternal and fetal disorders. When present, it can serve as an important indicator of chronic fetal hypoxia and predict poor obstetrical outcomes.","PeriodicalId":505527,"journal":{"name":"Clinical and Experimental Obstetrics & Gynecology","volume":" 31","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140387895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mei He, Ling Chen, Ningning Wang, Xinxin Ma, Yajun Wang, Yaming Zhang, Li Wang, Bing Zhao
Background : We investigated the mediating role of personality compatibility, couple communication, and sexual life in the psychological resilience and marital satisfaction of women with breast cancer. Methods : This is a cross-sectional survey. From March 2022 to June 2022, we enrolled 212 women with breast cancer from a tertiary tumor hospital in Xinjiang, China using a convenient sampling method. The basic information of patients was collected. The marriage quality and psychological resilience were assessed with the Enrich Marital Inventory and Connor-Davidson resilience scale, respectively. Counting data are expressed using the number and frequency while measuring data are presented using mean ± standard deviation. Statistical tests included one-way ANOVA and t -test. Pearson correlation was performed. The mediating effects were analyzed using the Baron and Kenny stepwise method. Results : The mean marriage quality score of women with breast cancer in marital satisfaction was 31.38 ± 8.36, in couple communication was 31.28 ± 7.15, in sexual life was 31.16 ± 7.76, in personality compatibility was 29.61 ± 7.32, and in psychological resilience was 53.60 ± 12.05, all of which were lower than the corresponding female norms. Correlation analysis showed that the three factors of psychological resilience (tenacity, strength, and optimism) of women with breast cancer were positively correlated with marital quality (marital satisfaction, personality compatibility, couple communication, and sexual life). The mediating effects of personality compatibility, couple communication, and sexual life on psychological resilience and marital satisfaction of women with breast cancer were significant ( p < 0.001). Their effect values accounted for 48.6%, 63.1%, and 64.4% of the total effects, respectively. Conclusions : The level of psychological resilience and marital satisfaction of women with breast cancer is low. Psychological resilience can not only directly affect the marital satisfaction of women with breast cancer, but also indirectly affect marital quality through personality compatibility, couple communication, and sexual life. Medical workers should pay attention to the psychological status and marital satisfaction of women with breast cancer.
{"title":"The Mediating Role of Personality Compatibility, Couple Communication, and Sexual Life in Psychological Resilience and Marital Satisfaction of Women with Breast Cancer","authors":"Mei He, Ling Chen, Ningning Wang, Xinxin Ma, Yajun Wang, Yaming Zhang, Li Wang, Bing Zhao","doi":"10.31083/j.ceog5103055","DOIUrl":"https://doi.org/10.31083/j.ceog5103055","url":null,"abstract":"Background : We investigated the mediating role of personality compatibility, couple communication, and sexual life in the psychological resilience and marital satisfaction of women with breast cancer. Methods : This is a cross-sectional survey. From March 2022 to June 2022, we enrolled 212 women with breast cancer from a tertiary tumor hospital in Xinjiang, China using a convenient sampling method. The basic information of patients was collected. The marriage quality and psychological resilience were assessed with the Enrich Marital Inventory and Connor-Davidson resilience scale, respectively. Counting data are expressed using the number and frequency while measuring data are presented using mean ± standard deviation. Statistical tests included one-way ANOVA and t -test. Pearson correlation was performed. The mediating effects were analyzed using the Baron and Kenny stepwise method. Results : The mean marriage quality score of women with breast cancer in marital satisfaction was 31.38 ± 8.36, in couple communication was 31.28 ± 7.15, in sexual life was 31.16 ± 7.76, in personality compatibility was 29.61 ± 7.32, and in psychological resilience was 53.60 ± 12.05, all of which were lower than the corresponding female norms. Correlation analysis showed that the three factors of psychological resilience (tenacity, strength, and optimism) of women with breast cancer were positively correlated with marital quality (marital satisfaction, personality compatibility, couple communication, and sexual life). The mediating effects of personality compatibility, couple communication, and sexual life on psychological resilience and marital satisfaction of women with breast cancer were significant ( p < 0.001). Their effect values accounted for 48.6%, 63.1%, and 64.4% of the total effects, respectively. Conclusions : The level of psychological resilience and marital satisfaction of women with breast cancer is low. Psychological resilience can not only directly affect the marital satisfaction of women with breast cancer, but also indirectly affect marital quality through personality compatibility, couple communication, and sexual life. Medical workers should pay attention to the psychological status and marital satisfaction of women with breast cancer.","PeriodicalId":505527,"journal":{"name":"Clinical and Experimental Obstetrics & Gynecology","volume":"108 44","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140088460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective : Adnexal torsion, a rare gynecological emergency, occurs in 10–20% of adnexal cases during pregnancy, and the risk is fivefold greater for pregnant women than for their non-pregnant counterparts. Pathological variations include ovarian-tubal, solely ovarian, and solely tubal torsion. Mechanism : Ultrasound examination stands out as the accurate, safe, and readily available primary method for assessing adnexal torsion during pregnancy. Treatment approaches encompass both conservative and surgical interventions, with surgery being the mainstay for definitive diagnosis and management. The evolving trend toward minimally invasive techniques has led to elevated laparoscopic surgery being the preferred method for addressing surgical diseases during pregnancy. Findings in Brief : Laparoscopic surgery offers several advantages, such as minimal trauma, reduced bleeding, diminished postoperative pain, faster recovery, lower thromboembolic event incidence, and shorter hospital stays. Furthermore, laparoscopy provides superior exposure to the surgical field in pregnant women, minimizing uterine disturbance and subsequently lowering the risks of miscarriage, preterm labor, and premature rupture of membranes. Conclusions : A nuanced approach is needed for patients with adnexal torsion during pregnancy, where ultrasound serves as a crucial diagnostic tool and surgical intervention, especially through laparoscopy, emerges as a favorable therapeutic strategy. The benefits of laparoscopic surgery extend beyond effective treatment to encompass reduced maternal risk and improved postoperative outcomes, making it a preferred option for managing adnexal torsion during pregnancy.
{"title":"Adnexal Torsion during Pregnancy Diagnosis, Treatment, and Prognosis","authors":"Rong Xu, Heng Zhang, Zhilong Yang","doi":"10.31083/j.ceog5103056","DOIUrl":"https://doi.org/10.31083/j.ceog5103056","url":null,"abstract":"Objective : Adnexal torsion, a rare gynecological emergency, occurs in 10–20% of adnexal cases during pregnancy, and the risk is fivefold greater for pregnant women than for their non-pregnant counterparts. Pathological variations include ovarian-tubal, solely ovarian, and solely tubal torsion. Mechanism : Ultrasound examination stands out as the accurate, safe, and readily available primary method for assessing adnexal torsion during pregnancy. Treatment approaches encompass both conservative and surgical interventions, with surgery being the mainstay for definitive diagnosis and management. The evolving trend toward minimally invasive techniques has led to elevated laparoscopic surgery being the preferred method for addressing surgical diseases during pregnancy. Findings in Brief : Laparoscopic surgery offers several advantages, such as minimal trauma, reduced bleeding, diminished postoperative pain, faster recovery, lower thromboembolic event incidence, and shorter hospital stays. Furthermore, laparoscopy provides superior exposure to the surgical field in pregnant women, minimizing uterine disturbance and subsequently lowering the risks of miscarriage, preterm labor, and premature rupture of membranes. Conclusions : A nuanced approach is needed for patients with adnexal torsion during pregnancy, where ultrasound serves as a crucial diagnostic tool and surgical intervention, especially through laparoscopy, emerges as a favorable therapeutic strategy. The benefits of laparoscopic surgery extend beyond effective treatment to encompass reduced maternal risk and improved postoperative outcomes, making it a preferred option for managing adnexal torsion during pregnancy.","PeriodicalId":505527,"journal":{"name":"Clinical and Experimental Obstetrics & Gynecology","volume":"16 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140083799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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