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Proposal for a permanent magnet system with a constant gradient mechanically adjustable in direction and strength 一种方向和强度可机械调节的恒梯度永磁系统的方案
IF 0.9 4区 医学 Q3 Chemistry Pub Date : 2016-02-27 DOI: 10.1002/cmr.b.21320
Peter BlüMler

A design for a permanent magnet system is proposed that generates spatially homogeneous, constant magnetic field gradients, thus creating conditions suitable for MRI without gradient coils and amplifiers. This is achieved by superimposing a weak Halbach quadrupole on a strong Halbach dipole. Rotation of either the quadrupole or the entire magnet assembly can be used to generate two-dimensional images via filtered backprojection. Additionally, the mutual rotation of two quadrupoles can be used to scale the resulting gradient. If both gradients have identical strength the gradient can even be made to vanish. The concept is demonstrated by analytical considerations and FEM simulations. However, a demonstration on a working prototype is still pending. © 2016 Wiley Periodicals, Inc. Concepts Magn Reson Part B (Magn Reson Engineering) 46B: 41–48, 2016

提出了一种永磁系统的设计,该系统产生空间均匀的恒定磁场梯度,从而为无需梯度线圈和放大器的MRI创造了条件。这是通过将弱哈尔巴赫四极子叠加在强哈尔巴赫偶极子上实现的。四极杆或整个磁铁组件的旋转可用于通过过滤后的反向投影生成二维图像。此外,两个四极杆的相互旋转可用于缩放所产生的梯度。如果两个梯度具有相同的强度,甚至可以使梯度消失。通过分析和有限元模拟验证了这一概念。然而,工作原型的演示仍在等待中。©2016 Wiley期刊公司机械工程B辑(机械工程),46 (1):41-48,2016
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引用次数: 34
Dependence of and field patterns of surface coils on the electrical properties of the sample and the MR operating frequency 表面线圈的磁场模式与样品电学特性和磁流变仪工作频率的关系
IF 0.9 4区 医学 Q3 Chemistry Pub Date : 2016-02-04 DOI: 10.1002/cmr.b.21319
Manushka V. Vaidya, Christopher M. Collins, Daniel K. Sodickson, Ryan Brown, Graham C. Wiggins, Riccardo Lattanzi

In high field MRI, the spatial distribution of the radiofrequency magnetic () field is usually affected by the presence of the sample. For hardware design and to aid interpretation of experimental results, it is important both to anticipate and to accurately simulate the behavior of these fields. Fields generated by a radiofrequency surface coil were simulated using dyadic Green's functions, or experimentally measured over a range of frequencies inside an object whose electrical properties were varied to illustrate a variety of transmit () and receive () field patterns. In this work, we examine how changes in polarization of the field and interference of propagating waves in an object can affect the spatial distribution. Results are explained conceptually using Maxwell's equations and intuitive illustrations. We demonstrate that the electrical conductivity alters the spatial distribution of distinct polarized components of the field, causing “twisted” transmit and receive field patterns, and asymmetries between and . Additionally, interference patterns due to wavelength effects are observed at high field in samples with high relative permittivity and near-zero conductivity, but are not present in lossy samples due to the attenuation of propagating EM fields. This work provides a conceptual framework for understanding spatial distributions for surface coils and can provide guidance for RF engineers. © 2016 Wiley Periodicals, Inc. Concepts Magn Reson Part B (Magn Reson Engineering) 46B: 25–40, 2016

在高场MRI中,射频磁场的空间分布通常受到样品存在的影响。对于硬件设计和帮助解释实验结果,预测和准确模拟这些场的行为是很重要的。射频表面线圈产生的场是用二进格林函数模拟的,或者是在一个物体内部的频率范围内进行实验测量,该物体的电学特性是不同的,以说明各种发射()和接收()场模式。在这项工作中,我们研究了场的偏振变化和传播波在物体中的干涉如何影响空间分布。使用麦克斯韦方程组和直观的插图对结果进行了概念性解释。我们证明了电导率改变了场中不同极化分量的空间分布,导致发射和接收场模式“扭曲”,以及和之间的不对称。此外,由于波长效应的干涉模式在高场中观察到具有高相对介电常数和接近零电导率的样品,但由于传播电磁场的衰减而不存在于损耗样品中。这项工作为理解表面线圈的空间分布提供了一个概念框架,并可以为射频工程师提供指导。©2016 Wiley期刊公司机械工程B辑(机械工程),46 (6):25-40,2016
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引用次数: 67
Permittivity measurement of liquids, powders, and suspensions using a parallel-plate cell 用平行板电池测量液体、粉末和悬浮液的介电常数
IF 0.9 4区 医学 Q3 Chemistry Pub Date : 2016-01-13 DOI: 10.1002/cmr.b.21318
Atefeh Kordzadeh, Nicola De Zanche

This work describes the measurement of complex permittivity (or dielectric constant) of powders (water insoluble), solutions, and suspensions using a parallel-plate capacitor cell. An impedance analyzer measures the cell's impedance at radio frequencies used in nuclear magnetic resonance and magnetic resonance imaging (10–300 MHz) through an appropriate test fixture. The cell's impedance is fitted to an equivalent circuit using a Matlab script or other software, and the permittivity of the material is extracted after calibration with known materials. The permittivity of the solid material is obtained from that of the powder suspension using known mixing rules. Measurements for most materials tested are in agreement with those obtained using standard coaxial probes. Some discrepancies are observed for loose powders because of the difficulty of controlling the amount of packing. For high-permittivity materials or conductive solutions an enhanced equivalent circuit has been found that characterizes the cell's behavior over the full frequency range. © 2016 Wiley Periodicals, Inc. Concepts Magn Reson Part B (Magn Reson Engineering) 46B: 19–24, 2016

这项工作描述了使用平行板电容器电池测量粉末(水不溶性)、溶液和悬浮液的复介电常数(或介电常数)。阻抗分析仪通过适当的测试夹具测量核磁共振和磁共振成像(10-300 MHz)使用的无线电频率下细胞的阻抗。使用Matlab脚本或其他软件将电池的阻抗拟合到等效电路中,并使用已知材料校准后提取材料的介电常数。固体材料的介电常数是根据已知的混合规则从粉末悬浮液的介电常数得到的。大多数材料的测量结果与使用标准同轴探头得到的结果一致。对于松散粉末,由于难以控制包装量,会观察到一些差异。对于高介电常数材料或导电溶液,已经发现了一种增强的等效电路,可以表征电池在整个频率范围内的行为。©2016 Wiley期刊公司概念物理推理B部分(物理推理工程)46 (6):19-24,2016
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引用次数: 12
Effects of anatomical differences on electromagnetic fields, SAR, and temperature change 解剖差异对电磁场、SAR和温度变化的影响
IF 0.9 4区 医学 Q3 Chemistry Pub Date : 2015-12-15 DOI: 10.1002/cmr.b.21317
Leeor Alon, Cem M. Deniz, Giuseppe Carluccio, Ryan Brown, Daniel K. Sodickson, Christopher M. Collins

Electromagnetic field simulations are increasingly used to assure RF safety of patients during MRI exams. In practice, however, tissue property distribution of the patient being imaged is not known, but may be represented with a pre-existing model. Repeatedly, agreement in transmit magnetic () field distributions between two geometries has been used to suggest agreement in heating distributions. Here we examine relative effects of anatomical differences on distribution, specific absorption rate (SAR), and temperature change (ΔT). Numerical simulations were performed for a single surface coil positioned adjacent a homogeneous phantom and bovine phantom, each with slight geometric variations, and adjacent two different human body models. Experimental demonstration was performed on a bovine phantom using MR thermometry and mapping. Simulations and experiments demonstrate that distributions in different samples can be well correlated, while notable difference in maximum SAR and ΔT occur. This work illustrates challenges associated with utilizing simulations or experiments for RF safety assurance purposes. Reliance on distributions alone for validation of simulations and/or experiments with a sample or subject for assurance of safety in another should be performed with caution. © 2015 Wiley Periodicals, Inc. Concepts Magn Reson Part B (Magn Reson Engineering) 46B: 8–18, 2016

电磁场模拟越来越多地用于确保患者在MRI检查期间的射频安全。然而,在实践中,被成像患者的组织特性分布是未知的,但可以用预先存在的模型表示。两种几何形状之间传输磁场分布的一致性一再被用来表明加热分布的一致性。在这里,我们研究了解剖差异对分布、比吸收率(SAR)和温度变化的相对影响(ΔT)。将单个表面线圈放置在具有轻微几何变化的均匀体模和牛体模之间,并与两个不同的人体模型相邻,进行了数值模拟。利用磁共振测温和成像技术在牛体上进行了实验演示。模拟和实验表明,不同样品的分布具有良好的相关性,但最大SAR和ΔT存在显著差异。这项工作说明了利用模拟或实验来保证射频安全的挑战。仅依靠分布来验证模拟和/或用样品或对象进行的实验,以确保在另一个样品或对象中的安全性,应谨慎进行。©2015 Wiley期刊公司机械工程B辑(工学版),46 (1):8-18,2016
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引用次数: 24
An RF breast coil for 0.2T MRI 用于0.2T MRI的射频乳房线圈
IF 0.9 4区 医学 Q3 Chemistry Pub Date : 2015-11-12 DOI: 10.1002/cmr.b.21316
Barbara Blasiak, Vyacheslav Volotovskyy, Randy Tyson, Jonathan Sharp, Boguslaw Tomanek

Breast cancer is the most frequently diagnosed cancer in women. High field studies have shown the diagnostic value of breast MRI, but the examination costs greatly exceed those of competing conventional mammography. Low field MRI offers typical MRI contrast at substantially lower cost, but has suffered from lower spatial resolution. Specificity of breast MRI can potentially be increased by acquiring MR imaging with higher spatial or temporal resolution, but the signal-to-noise ratio (SNR) achievable in a given imaging time becomes limiting. SNR for the particular pulse sequence and magnet field strength is strongly influenced by the characteristics of the radio-frequency coil. An optimal breast coil should yield excellent SNR but also generate a homogeneous B1 field, while allowing imaging of the both breasts simultaneously and maintaining patient comfort. RF receiver coil design is a key determinant of image quality, thus to address this we have designed and constructed a low field breast imaging coil. The coil was tested with a 4-post 0.2T MRI providing high quality breast images. Designed and constructed saddle rf coil allows to obtain good quality image of the breast using low 0.2 T MRI system within 2 minutes. The coil provides patient comfort as breast compression is not required and minimizes artefacts caused by respiration or motion. A high contrast, low-cost and pain-free breast examination using optimized low field MRI system has the potential to serve a large patient population for whom current technologies have deficiencies. © 2015 Wiley Periodicals, Inc. Concepts Magn Reson Part B (Magn Reson Engineering) 46B: 3–7, 2016

乳腺癌是女性中最常见的癌症。高场研究显示了乳房MRI的诊断价值,但其检查费用大大超过了与之竞争的传统乳房x光检查。低场MRI以较低的成本提供典型的MRI对比,但空间分辨率较低。乳房MRI的特异性可以通过获得更高的空间或时间分辨率的磁共振成像来提高,但在给定的成像时间内可实现的信噪比(SNR)变得有限。特定脉冲序列和磁场强度的信噪比受射频线圈特性的强烈影响。最佳的乳房线圈应产生优异的信噪比,同时产生均匀的B1场,同时允许对两个乳房进行成像,并保持患者的舒适度。射频接收器线圈的设计是图像质量的关键决定因素,因此,为了解决这个问题,我们设计并构建了一个低场乳房成像线圈。用4柱0.2T MRI检测线圈,提供高质量的乳房图像。设计和构建的鞍形射频线圈允许使用低0.2 T MRI系统在2分钟内获得高质量的乳房图像。线圈为患者提供舒适,因为乳房不需要压缩,并最大限度地减少呼吸或运动引起的人工制品。使用优化的低场MRI系统进行高对比度、低成本和无痛的乳房检查,有可能为当前技术存在缺陷的大量患者提供服务。©2015 Wiley期刊公司核电工程B辑(核电工程),第46期,第3-7期,2016
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引用次数: 3
NMR Concepts 核磁共振的概念
IF 0.9 4区 医学 Q3 Chemistry Pub Date : 2015-10-28 DOI: 10.1002/cmr.b.21315
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引用次数: 0
DVD Review DVD的评论
IF 0.9 4区 医学 Q3 Chemistry Pub Date : 2015-10-28 DOI: 10.1002/cmr.b.21314
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引用次数: 0
Practical design of multi-channel MOSFET RF transmission system for 7 T animal MR imaging 用于7 T动物磁共振成像的多通道MOSFET射频传输系统的实用设计
IF 0.9 4区 医学 Q3 Chemistry Pub Date : 2015-10-23 DOI: 10.1002/cmr.b.21313
Yizhe Zhang, Yan Liu, Bingyao Sun, Xiaoliang Zhang, Xiaohua Jiang

In this work, we developed and tested a multi-channel radio frequency (RF) transmission system with compact metal-oxide semiconductor field effect transistor (MOSFET) amplifiers for parallel excitation in 7 T animal MRI scanner. The system is composed of a multi-channel RF controller and four independent RF power amplifiers. Each power amplifier contains two amplification stages. The design was validated by simulation and bench test. The power gain for the amplifier is 18.7 dB at 300 MHz, demonstrating the sufficient amplification capability of the transmission system for small animal parallel excitation applications at 7 T. This compact RF power amplifier can be potentially used for on-coil amplification in multichannel RF array system. © 2015 Wiley Periodicals, Inc. Concepts Magn Reson Part B (Magn Reson Engineering) 45B: 191–200, 2015

在这项工作中,我们开发并测试了一种多通道射频(RF)传输系统,该系统具有紧凑型金属氧化物半导体场效应晶体管(MOSFET)放大器,用于7 T动物MRI扫描仪的并联激励。该系统由一个多通道射频控制器和四个独立的射频功率放大器组成。每个功率放大器包含两个放大级。通过仿真和台架试验验证了设计的正确性。该放大器在300 MHz时的功率增益为18.7 dB,证明了该传输系统在7 t时对小型动物并联激励应用具有足够的放大能力。该紧凑型射频功率放大器可用于多通道射频阵列系统的线圈放大。©2015 Wiley期刊公司工程机械学报(自然科学版),第1期,第2 - 3节,2015
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引用次数: 2
Theoretical analysis of magnetic wall decoupling method for radiative antenna arrays in ultrahigh magnetic field MRI 超高磁场MRI中辐射天线阵列磁壁解耦方法的理论分析
IF 0.9 4区 医学 Q3 Chemistry Pub Date : 2015-10-19 DOI: 10.1002/cmr.b.21312
Xinqiang Yan, Zhentian Xie, Jan Ole Pedersen, Xiaoliang Zhang

Radiative antenna techniques, e.g., dipole and monopole, have been proposed for radiofrequency (RF) coil array designs in ultrahigh field MRI to obtain stronger B1 field and higher signal-to-noise ratio (SNR) gain in the areas deep inside human head or body. It is known that element decoupling performance is crucial to SNR and parallel imaging ability of array coil and has been a challenging issue in radiative antenna array designs for MR imaging. Magnetic wall or induced current elimination (ICE) technique has proven to be a simple and effective way of achieving sufficient decoupling for radiative array coils experimentally. In this study, this decoupling technique for radiative coil array was analyzed theoretically and verified by a simulation study. The decoupling conditions were derived and obtained from the theory. By applying the predicated decoupling conditions, the isolation of two radiative elements could be improved from about 8 dB to better than 35 dB. The decoupling performance has also been validated by current distribution along the radiative elements and magnetic field profiles in a water phantom. © 2015 Wiley Periodicals, Inc. Concepts Magn Reson Part B (Magn Reson Engineering) 45B: 183–190, 2015

辐射天线技术,如偶极子和单极子,已被提出用于超高场MRI射频(RF)线圈阵列设计,以获得更强的B1场和更高的信噪比(SNR)增益在人体头部或身体深处区域。元件去耦性能对阵列线圈的信噪比和并行成像能力至关重要,是磁共振成像辐射天线阵列设计中的一个难题。实验证明,磁壁或感应电流消除技术是实现辐射阵列线圈充分去耦的一种简单有效的方法。本文对辐射线圈阵列的解耦技术进行了理论分析和仿真研究。从理论上推导并得到了解耦条件。通过应用预测的解耦条件,两个辐射元件的隔离度可以从−8 dB左右提高到−35 dB以上。通过水模体中沿辐射单元和磁场剖面的电流分布验证了解耦性能。©2015 Wiley期刊公司工程机械学报(自然科学版),第4期,第1 -第2期,2015
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引用次数: 9
A novel switched frequency 3He/1H high-pass birdcage coil for imaging at 1.5 tesla 一种用于1.5特斯拉成像的新型开关频率3He/1H高通鸟笼线圈
IF 0.9 4区 医学 Q3 Chemistry Pub Date : 2015-10-06 DOI: 10.1002/cmr.b.21309
Ronald Pratt, Randy Giaquinto, Christopher Ireland, Barret Daniels, Wolfgang Loew, Nara Higano, Xuefeng Cao, Robert Thomen, Jason Woods, Charles L. Dumoulin

The ability to produce hyperpolarized noble gases 3He and 129Xe has opened up exciting possibilities for pulmonary magnetic resonance imaging (MRI). We have recently built a hyperpolarizer with the goal of using hyperpolarized 3He gas for MRI in neonatal lungs in a dedicated small foot-print 1.5 T MR scanner developed at our institution and sited in our Neonatal Intensive Care Unit. Although hyperpolarized gas imaging can provide unique insights into lung ventilation, acinar microstructure, and gas-exchange dynamics, there is an undiminished need for 1H MRI of the lung to provide anatomic references, B1 and B0 maps, and 1H images of lung parenchyma. To address this need, we designed, built and tested a novel radiofrequency body coil that provides a high-pass birdcage coil that can be used for both 3He and 1H frequencies (48.65 and 63.86 MHz, respectively, at 1.5 T). To switch between frequencies, the birdcage coil has a large mechanical actuator that simultaneously changes the capacitance between every rung of the birdcage. Advantages of this coil design include: 1) quadrature excitation and reception at the 3He and 1H frequencies, 2) identical B1 field maps for 3He and 1H imaging, 3) excellent signal-to-noise ratio and B1 homogeneity at both frequencies, and 4) rapid (10–20 s) switching times between 3He and 1H operation. This report provides details of the coil's design and fabrication. Images of hyperpolarized 3He and 1H in phantoms and ex vivo rabbit lungs demonstrate the image quality obtained with the coil. © 2015 Wiley Periodicals, Inc. Concepts Magn Reson Part B (Magn Reson Engineering) 45B: 174–182, 2015

产生超极化惰性气体3He和129Xe的能力为肺部磁共振成像(MRI)开辟了令人兴奋的可能性。我们最近建立了一个超偏振器,目标是使用超偏振3He气体在我们机构开发的专用小型占地1.5 T MR扫描仪中对新生儿肺部进行MRI。虽然超极化气体成像可以提供对肺通气、腺泡微观结构和气体交换动力学的独特见解,但仍然需要肺1H MRI提供解剖学参考、B1和B0图以及肺实质的1H图像。为了满足这一需求,我们设计、制造并测试了一种新型射频体线圈,该线圈提供了一种高频鸟笼线圈,可用于3He和1H频率(分别为48.65和63.86 MHz, 1.5 T)。为了在频率之间切换,鸟笼线圈有一个大型机械执行器,可以同时改变鸟笼每个梯级之间的电容。该线圈设计的优点包括:1)3He和1H频率下的正交激励和接收,2)3He和1H成像的相同B1场图,3)两个频率下良好的信噪比和B1均匀性,4)3He和1H工作之间的快速切换时间(10-20秒)。本报告提供了线圈的设计和制造的细节。超偏振3He和1H在兔肺和离体兔肺中的图像显示了线圈获得的图像质量。©2015 Wiley期刊公司工程机械学报(自然科学版),2015,31 (1):1 - 4
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引用次数: 7
期刊
Concepts in Magnetic Resonance Part B-Magnetic Resonance Engineering
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