Clinical Implant Dentistry and Related Research最新文献_第5页

Progressive bone loss and bleeding on probing: A cohort study 渐进性骨质流失和探针出血：一项队列研究。

IF 3.7 2区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Clinical Implant Dentistry and Related Research

Pub Date : 2024-06-23 DOI: 10.1111/cid.13356

Ausra Ramanauskaite DDS, Dr. Med. Dent., PhD, Ninad Padhye DDS, Sandra Kallab Dr. Med. Dent, Iulia Dahmer PhD, Amira Begic Dr. Med. Dent, Stefanie Tiede DDS, Frank Schwarz Prof., DDS, Dr. Med. Dent

Aim

To investigate whether a progressive marginal bone loss (PMBL) occurring beyond the initial bone remodeling (IBR) is linked with bleeding on probing.

Materials and Methods

A total of 70 partially edentulous patients exhibiting 112 two-piece bone-level implants were included in this retrospective study. Panoramic radiographs were obtained after implant insertion (T0), after delivery of a final prosthetic restoration (T1) and subsequently during the 1-(T2), 5-(T3), 10-(T4), and 15-years (T5) follow-up visits. At each time point, radiographic marginal bone levels were assessed from the implant shoulder to the first bone-to-implant contact at mesial and distal aspects. The IBR was defined as a bone loss occurring up to prosthesis delivery, that is, from T0 to T1. The PMBL was defined as bone loss occurring after T1. At T2, T3, T4, and T5, the presence or absence of bleeding on probing (BOP) was recorded at four sites. A median regression with mixed models was performed to assess the difference of PMBL in PMBL + BOP⁺ and PBML + BOP⁻ groups.

Results

Over the mean implant functioning time of 4.44 ± 4.91 years, 38 (34%) implants showed no PBML, whereas 74 (66%) implants featured PMBL. Of these, 35 (47%) and 39 (53%) implants were assigned to the PMBL + BOP⁻ and PMBL + BOP⁺ groups, respectively. The mean PMBL after 1, 5, 10, and 15 years were comparable between implants featuring PMBL with or without BOP. At 1 year, BOP intensity significantly correlated PMBL, with each increase in one BOP-positive site being associated with increase in PMBL by 0.55 mm (p = 0.038), whereas this association was not found at 5, 10, and 15 years. The IBR values in the no PBML, PMBL + BOP⁺, and PBML + BOP⁻ groups were −0.24 ± 0.31, −0.41 ± 0.59, and −0.24 ± 0.33 mm, respectively, with no significant differences found among the groups.

Conclusion

Progressive bone loss at implant sites is not always linked with bleeding on probing.

目的：研究在初始骨重塑（IBR）后出现的渐进性边缘骨缺损（PMBL）是否与探诊出血有关：这项回顾性研究共纳入了 70 名部分缺牙患者，他们共植入了 112 颗两件式骨水平种植体。在种植体植入后（T0）、最终修复体交付后（T1）以及随后的 1 年（T2）、5 年（T3）、10 年（T4）和 15 年（T5）随访期间分别拍摄了全景照片。在每个时间点，都会对从种植体肩部到种植体中、远端第一次骨与种植体接触处的边缘骨水平进行放射学评估。IBR 被定义为假体植入前发生的骨质流失，即从 T0 到 T1。PMBL 被定义为 T1 之后发生的骨质流失。在T2、T3、T4和T5，记录四个部位是否有探诊出血（BOP）。采用混合模型进行中位回归，以评估 PMBL + BOP+ 组和 PBML + BOP- 组中 PMBL 的差异：在平均 4.44 ± 4.91 年的种植体功能时间内，38 个（34%）种植体没有出现 PBML，而 74 个（66%）种植体出现了 PMBL。其中，35 个（47%）和 39 个（53%）种植体分别被分配到 PMBL + BOP- 组和 PMBL + BOP+ 组。1年、5年、10年和15年后的平均PMBL值在使用或不使用BOP的植入物之间具有可比性。1 年时，BOP 强度与 PMBL 显著相关，BOP 阳性部位每增加一个，PMBL 就会增加 0.55 mm（p = 0.038），而在 5、10 和 15 年时，则没有发现这种关联。无 PBML 组、PMBL + BOP+ 组和 PBML + BOP- 组的 IBR 值分别为 -0.24 ± 0.31、-0.41 ± 0.59 和 -0.24 ± 0.33 mm，各组间无显著差异：结论：种植部位的骨质逐渐流失并不总是与探诊出血有关。

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引用次数: 0

Histomorphometric and microtomographic analysis of maxillary sinus augmentation surgeries with and without collagen membrane on the lateral window: A randomized clinical trial 上颌窦侧窗有胶原膜和无胶原膜隆鼻手术的组织形态计量学和显微断层扫描分析：随机临床试验

IF 3.7 2区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Clinical Implant Dentistry and Related Research

Pub Date : 2024-06-21 DOI: 10.1111/cid.13331

Ramiro Beato Souza DDS, MDSc, PhD, Haimon Diniz Lopes Alves DDS, MDSc, PhD, Luciano Santos Oliveira DDS, MDSc, PhD, Fabio Ramoa Pires DDS, MDSc, PhD, Guaracilei Maciel Vidigal Jr DDS, MDSc, PhD, Ricardo Guimaraes Fischer MD, DDS, MDSc, PhD

Objective

To evaluate the histomorphometric and computerized microtomographic (Micro-CT) analysis of the regenerated bone tissue from maxillary sinus augmentation surgery, with and without using the collagen membrane on the external osteotomy window.

Materials and Methods

Twelve patients were selected for this prospective, controlled, and randomized study. The patients were submitted to bilateral maxillary sinus surgery in a split-mouth design. On the test side, the maxillary sinus augmentation procedure included using Geistlich Bio-Oss® and a Geistlich Bio-Gide® collagen membrane covering the lateral osteotomy window. On the control side, only Geistlich Bio-Oss® was used without the presence of the membrane. After 6 months, the surgeries for implant installation were performed. In this surgical phase, specimens of the regenerated tissue were collected for histological and Micro-CT analysis.

Results

In the histomorphometric evaluation, the mean (±SD) percentages of newly formed bone were 43.9% (±11.5) and 40.8% (±8.9) in the test and control groups, respectively. The corresponding values of the Micro-CT analysis were 36.6% (±3.4) and 37.2% (±4.7) in the test and control groups, respectively. There was no statistically significant difference between the test and control groups in the two methods. In addition, there was no statistically significant difference between the mean percentage of biomaterial remaining between the test and control groups. However, the mean percentage of newly formed bone was significantly higher and the mean percentage of remaining biomaterial was significantly lower in the histomorphometric analysis compared to the values obtained through microtomography.

Conclusion

The additional use of collagen membranes in maxillary sinus surgery does not offer advantages in newly formed bone.

材料和方法这项前瞻性、对照和随机研究选择了 12 名患者。患者采用分口设计接受双侧上颌窦手术。在试验侧，上颌窦增量手术包括使用 Geistlich Bio-Oss® 和覆盖侧截骨窗的 Geistlich Bio-Gide® 胶原膜。对照组只使用 Geistlich Bio-Oss®，不使用薄膜。6 个月后，进行种植体安装手术。结果在组织形态学评估中，试验组和对照组新形成骨的平均百分比（±SD）分别为 43.9%（±11.5）和 40.8%（±8.9）。在 Micro-CT 分析中，试验组和对照组的相应数值分别为 36.6%（±3.4）和 37.2%（±4.7）。试验组和对照组在两种方法上的差异无统计学意义。此外，试验组和对照组剩余生物材料的平均百分比也没有明显的统计学差异。然而，与通过显微断层扫描获得的数值相比，组织形态计量分析中新形成骨的平均百分比明显更高，而剩余生物材料的平均百分比则明显更低。

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引用次数: 0

3D evaluation of sagittal inclination of the maxillary dentition in relation to facial landmarks: A cohort study 上颌牙齿矢状倾角与面部地标的关系的三维评估：一项队列研究。

IF 3.7 2区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Clinical Implant Dentistry and Related Research

Pub Date : 2024-06-12 DOI: 10.1111/cid.13351

Basel El-Sabbagh, Kathrin Seidel DMD, Babak Sayahpour DMD, Jan-Frederik Güth DMD, PhD

<div> <section> <h3> Background</h3> <p>The determination of the maxillary occlusal plane presents a significant clinical challenge in the treatment of edentulous patients as well as it is critical for complex full-mouth reconstructions in dentate patients, including those with implant-supported rehabilitations. While the use of a Fox plane plate is standard in edentulous cases, its application in dentate patients lacks thorough documentation in existing literature.</p> </section> <section> <h3> Purpose</h3> <p>This clinical study assessed the sagittal position of the maxillary dentition in relation to facial landmarks using a digital three-dimensional analysis and evaluated the suitability and reliability of applying a simulated Fox plane plate, also known as an occlusal plane guide, in dentate patients.</p> </section> <section> <h3> Materials and Methods</h3> <p>Eighty-one subjects were recruited at the Department of Prosthetic Dentistry of Goethe University Frankfurt, Germany, according to specific inclusion criteria. Intraoral and facial scans were obtained and analyzed using GOM Inspect Pro software (GOM, Braunschweig, Germany). The angles between the maxillary occlusal plane and three variations each of Camper's plane and ala-tragus line, relating to superior, middle, and inferior tragus points, were measured. These modified planes were then compared to a plane established by a simulated digital Fox plane plate, which was adapted to the maxillary anterior teeth and the lowest point of the posterior teeth in both quadrants.</p> </section> <section> <h3> Results</h3> <p>A total of 81 subjects (58 female and 23 male) with a mean age of 23.9 years were evaluated in this study. No significant angular difference was found between the angles of the maxillary occlusal plane compared with superior Camper's plane, middle Camper's plane, or superior ala-tragus line (<i>p</i> >0.05). The smallest angle occurred between superior Camper's plane and the maxillary occlusal plane on both the right (3.443°) and left (3.535°) sides. The application of a Fox plane plate resulted in two different occlusal planes in 70% of patients, significantly deviating from the digitally determined plane (<i>p</i> <0.05).</p> </section> <section> <h3> Conclusion</h3> <p>Superior and middle Camper's planes, along with superior ala-tragus line, can be considered approximately parallel reference planes and are suitable for routine determining of the maxillary occlusal plane

背景：上颌咬合平面的确定是无牙颌患者治疗中的一个重大临床挑战，同时也是有牙患者复杂全口重建的关键，包括那些接受种植体支持修复的患者。目的：这项临床研究使用数字三维分析评估了上颌牙体与面部地标的矢状位置关系，并评估了在无牙颌患者中使用模拟福克斯平面板（也称为咬合平面引导板）的适宜性和可靠性：根据特定的纳入标准，在德国法兰克福歌德大学修复牙科系招募了 81 名受试者。使用 GOM Inspect Pro 软件（GOM，德国布伦瑞克）获取口内和面部扫描结果并进行分析。测量了上颌咬合平面与坎珀平面和腭嵴线各三个变体之间的角度，分别与上、中、下腭嵴点有关。然后将这些修改后的平面与模拟数字福克斯平面板建立的平面进行比较，该平面与上颌前牙和两个象限后牙的最低点相适应：本研究共评估了 81 名受试者（58 名女性和 23 名男性），他们的平均年龄为 23.9 岁。上颌咬合面的角度与上康氏面、中康氏面或上腭嵴线的角度相比没有发现明显的角度差异（P>0.05）。右侧（3.443°）和左侧（3.535°）康帕上平面与上颌咬合平面之间的角度最小。70% 的患者在使用 Fox 平面板后会出现两个不同的咬合平面，与数字确定的平面有明显偏差（p 结论：Fox 平面板与数字确定的咬合平面有明显偏差：上、中Camper平面以及上ala-ragus线可视为近似平行的参考平面，适用于修复治疗中上颌咬合平面的常规确定。然而，与数字评估方法相比，在牙质较好的患者中应用福克斯平面板的变异性很大，这表明由于其在上颌牙体上的定位不明确，其可重复性很低。临床试验注册网站：https://drks.de/search/de/trial/DRKS00030166。

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引用次数: 0

Clinical, radiographic, and aesthetic outcomes at two narrow-diameter implants to replace congenital missing maxillary lateral incisors: A 3-year prospective, clinical study 用两颗窄直径种植体替代先天性上颌侧切牙缺失的临床、放射学和美学效果：为期 3 年的前瞻性临床研究。

IF 3.7 2区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Clinical Implant Dentistry and Related Research

Pub Date : 2024-06-11 DOI: 10.1111/cid.13339

Andrea Roccuzzo DDS, MAS, PhD, Jean-Claude Imber DDS, MAS, Jakob Lempert DDS, Simon Storgård Jensen DDS

Introduction

To present the 3-year clinical, radiographic, and aesthetic outcomes in patients with congenitally missing lateral incisors rehabilitated with two narrow-diameter implants (NDIs).

Methods

The original population consisted of 100 patients rehabilitated with a cement-retained bi-layered zirconia single-unit crown supported by either a Ø2.9 mm (Test) or a Ø3.3 mm (Control) NDI (n = 50). At the 1- and 3-year follow-up (T2, T3), implant survival rate, crestal bone level (CBL) changes, biological, and technical complications were recorded, while the assessment of the aesthetic outcomes was performed using the Copenhagen Index Score.

Results

Seventy-four patients Ø2.9 mm (n = 39) or Ø3.3 mm (n = 35) reached T3, as 24 patients were lost to follow-up and 1 implant (Ø3.3 mm) was removed. Throughout the observation period, minimal CBL changes (i.e., <1 mm) were detected between groups. Despite the positive aesthetic scores recorded (i.e., 1–2), at T3 20% of patients rehabilitated with a Ø3.3 mm versus 2.6% of patients Ø2.9 mm displayed an alveolar process deficiency (Score 3). No additional technical and/or mechanical complications were recorded between T2 and T3. Tooth vitality was maintained in all neighboring teeth. Peri-implant probing depths and plaque scores remained low in both groups (p > 0.05).

Conclusion

The use of 2.9 or 3.3 diameter implants showed comparable favorable mid-term results in terms of survival rate, CBL, and aesthetic outcomes. Hence, clinicians should rely on the use of such NDIs when replacing maxillary lateral incisors.

简介：目的目的：介绍先天性侧切牙缺失患者使用两个窄直径种植体（NDI）进行修复的3年临床、放射学和美学效果：最初的研究对象包括 100 名患者，他们在直径为 2.9 毫米的 NDI（试验）或直径为 3.3 毫米的 NDI（对照）（n = 50）的支持下，使用水泥固位的双层氧化锆单冠进行修复。随访1年和3年（T2、T3）时，记录种植体存活率、基底骨水平（CBL）变化、生物学和技术并发症，并使用哥本哈根指数评分评估美学效果：74名直径为2.9毫米（39人）或直径为3.3毫米（35人）的患者达到了T3，24名患者失去了随访机会，1颗直径为3.3毫米的种植体被移除。在整个观察期间，CBL的变化极小（即0.05）：结论：在存活率、CBL和美学效果方面，使用直径为2.9或3.3的种植体都能获得相当好的中期效果。因此，临床医生在替换上颌侧切牙时，应使用这种 NDI。

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引用次数: 0

Emergence of artificial intelligence for automating cone-beam computed tomography-derived maxillary sinus imaging tasks. A systematic review 用于自动完成锥形束计算机断层扫描上颌窦成像任务的人工智能的兴起。系统综述。

IF 3.7 2区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Clinical Implant Dentistry and Related Research

Pub Date : 2024-06-11 DOI: 10.1111/cid.13352

Sohaib Shujaat, Abdulmohsen Alfadley, Nermin Morgan, Ahmed Jamleh, Marryam Riaz, Ali Anwar Aboalela, Reinhilde Jacobs

Cone-beam computed tomography (CBCT) imaging of the maxillary sinus is indispensable for implantologists, offering three-dimensional anatomical visualization, morphological variation detection, and abnormality identification, all critical for diagnostics and treatment planning in digital implant workflows. The following systematic review presented the current evidence pertaining to the use of artificial intelligence (AI) for CBCT-derived maxillary sinus imaging tasks. An electronic search was conducted on PubMed, Web of Science, and Cochrane up until January 2024. Based on the eligibility criteria, 14 articles were included that reported on the use of AI for the automation of CBCT-derived maxillary sinus assessment tasks. The QUADAS-2 (Quality Assessment of Diagnostic Accuracy Studies 2) tool was used to evaluate the risk of bias and applicability concerns. The AI models used were designed to automate tasks such as segmentation, classification, and prediction. Most studies related to automated maxillary sinus segmentation demonstrated high performance. In terms of classification tasks, the highest accuracy was observed for diagnosing sinusitis (99.7%), whereas the lowest accuracy was detected for classifying abnormalities such as fungal balls and chronic rhinosinusitis (83.0%). Regarding implant treatment planning, the classification of automated surgical plans for maxillary sinus floor augmentation based on residual bone height showed high accuracy (97%). Additionally, AI demonstrated high performance in predicting gender and sinus volume. In conclusion, although AI shows promising potential in automating maxillary sinus imaging tasks which could be useful for diagnostic and planning tasks in implantology, there is a need for more diverse datasets to improve the generalizability and clinical relevance of AI models. Future studies are suggested to focus on expanding the datasets, making the AI model's source available, and adhering to standardized AI reporting guidelines.

上颌窦的锥形束计算机断层扫描（CBCT）成像对于种植医生来说是不可或缺的，它可以提供三维解剖可视化、形态变异检测和异常识别，这些对于数字化种植工作流程中的诊断和治疗规划都至关重要。以下系统性综述介绍了目前有关将人工智能（AI）用于 CBCT 衍生的上颌窦成像任务的证据。我们在 PubMed、Web of Science 和 Cochrane 上进行了电子检索，截止日期为 2024 年 1 月。根据资格标准，共纳入了 14 篇报道人工智能用于 CBCT 衍生上颌窦评估任务自动化的文章。QUADAS-2（诊断准确性研究质量评估 2）工具用于评估偏倚风险和适用性问题。所使用的人工智能模型旨在自动完成分割、分类和预测等任务。大多数与上颌窦自动分割相关的研究都显示出很高的性能。在分类任务方面，诊断鼻窦炎的准确率最高（99.7%），而对真菌球和慢性鼻炎等异常情况进行分类的准确率最低（83.0%）。在种植治疗计划方面，根据残余骨高度对上颌窦底增高的自动手术计划进行分类的准确率很高（97%）。此外，人工智能在预测性别和上颌窦容积方面也表现出色。总之，虽然人工智能在上颌窦成像任务自动化方面显示出了巨大的潜力，可用于种植学的诊断和规划任务，但仍需要更多样化的数据集来提高人工智能模型的通用性和临床相关性。建议今后的研究重点放在扩大数据集、公开人工智能模型的来源以及遵守标准化的人工智能报告指南上。

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引用次数: 0

Clinical efficacy of a two-piece abutment conforming to the concept of one abutment one time in the posterior region: A clinical pilot study 符合后牙区一次一基台概念的两件式基台的临床疗效：临床试验研究。

IF 3.7 2区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Clinical Implant Dentistry and Related Research

Pub Date : 2024-06-06 DOI: 10.1111/cid.13349

Jimin Jiang MDS, Hang Yang MDS, Han Zhu MDS, Ibrahim El Khalil Bouhamed MDS, Xiaoting Shen MD, Hongye Lu MD, Fuming He MD

Objectives

To assess the impact of a two-piece abutment workflow on enhancing the stability of the alveolar bone and gingiva surrounding the dental implant, and to determine the level of patient satisfaction.

Materials and Methods

A total of 48 patients with dentition defect in the posterior region were included and divided into two groups: the two-piece abutment workflow (TAW) and the sealing screw with submerged healing workflow (SHW). Marginal bone level (MBL), soft tissue indicators, oral hygiene indicators, and patient satisfaction were assessed and recorded partially at 0, 3, 6, and 12 months after surgery. The primary outcome was the change of MBL in different time periods. A generalized linear mixed model (GLMM) was used to take into account the correlated nature of the data, and adjust for potential confounding factors within inter-group differences.

Results

The survival rate of implants and prosthesis reached 100% at 12-month follow-up, with an average decrease of 0.25 mm (SD 0.23 mm) of MBL in the TAW group and 0.48 mm (SD 0.45 mm) in the SHW group. The change of MBL in the TAW group (0.15 ± 0.31 mm) was significantly lower than the SHW group (0.41 ± 0.41 mm) through the analysis of GLMM within 6 months, while no significance was found in 12 months. Moreover, less gingival pain and oppression during prosthesis loading, and less time consumption overall duration were showed in the TAW group through Visual Analogue Scale (VAS, p < 0.05).

Conclusions

Within a 6-month period, the two-piece abutment workflow showed superior efficacy in preserving the integrity of the marginal bone level. Furthermore, it streamlined treatment procedures and mitigated discomfort, hence increasing patient satisfaction.

目的评估两件式基台工作流程对提高种植牙周围牙槽骨和牙龈稳定性的影响，并确定患者的满意度：共纳入48名后部牙列缺损患者，并将其分为两组：两件式基台工作流程（TAW）和浸没式愈合密封螺钉工作流程（SHW）。在术后 0、3、6 和 12 个月对边缘骨水平 (MBL)、软组织指标、口腔卫生指标和患者满意度进行部分评估和记录。主要结果是不同时间段内边缘骨水平的变化。使用广义线性混合模型（GLMM）来考虑数据的相关性，并调整组间差异中的潜在混杂因素：结果：随访 12 个月时，种植体和假体的存活率达到 100%，TAW 组 MBL 平均下降 0.25 毫米（标度 0.23 毫米），SHW 组 MBL 平均下降 0.48 毫米（标度 0.45 毫米）。通过 GLMM 分析，在 6 个月内，TAW 组 MBL 的变化（0.15 ± 0.31 mm）明显低于 SHW 组（0.41 ± 0.41 mm），而在 12 个月内则无显著性差异。此外，通过视觉模拟量表（VAS，P）显示，TAW 组在装载假牙时牙龈疼痛和压迫感较轻，整个持续时间耗时较短：在 6 个月的时间内，两件式基台工作流程在保持边缘骨水平的完整性方面表现出了卓越的功效。此外，它还简化了治疗程序，减轻了不适感，从而提高了患者的满意度。

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引用次数: 0

Effects of sterilization and disinfection methods on digitally designed surgical implant guide accuracy: An in vitro study 灭菌和消毒方法对数字化设计的外科植入物导板精确度的影响：体外研究。

IF 3.7 2区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Clinical Implant Dentistry and Related Research

Pub Date : 2024-05-29 DOI: 10.1111/cid.13350

Ruikun Li, Jie Zhu, Shuo Wang, Xueyuan Li, Songhang Li

Introduction

Surgical guides are commonly used to assist with dental implant placement. This study investigated the effects of five sterilization and disinfection methods on the accuracy of implant guides.

Methods

Thirty surgical guides (five in each group) were designed and printed (with digital light processing technology) using different sterilization or disinfection methods categorized into six groups: hydrogen peroxide sterilization (group one); glutaraldehyde sterilization (group two); autoclaving (group three); plasma sterilization (group four); iodophor disinfection (group five); and blank group (group six). Verification was determined using three methods: distance and angle between the cross-shaped marks, deformation after superimposing the guides, and displacement and axial changes in the virtual implant.

Results

After disinfection and sterilization, the guides in the autoclaving and iodophor groups showed a more pronounced color change and the guide in the autoclaving group had visible cracks. More significant changes were observed in the H₂O₂, glutaraldehyde, autoclaving, and iodophor groups regarding deformation after superimposing the guides and the distance and angle between the cross-shaped marks. The average labial deformation values (mm) of the first through fifth groups of guides were 0.283, 0.172, 0.289, 0.153, and 0.188, respectively. All groups were statistically different from the blank group for displacement and axial changes of the virtual implant (p < 0.05).

Conclusion

The sizes of almost all surgical guides changed after sterilization and disinfection treatments, with between-group differences. Plasma sterilization was more suitable for surgical guide sterilization because of the smaller deformations after treatment.

导言：手术导板通常用于辅助牙科种植体的植入。本研究调查了五种消毒和灭菌方法对种植导板准确性的影响：采用不同的消毒或灭菌方法设计和打印了 30 个手术导板（每组 5 个），并将其分为六组：过氧化氢消毒组（第一组）、戊二醛消毒组（第二组）、高压灭菌组（第三组）、等离子消毒组（第四组）、碘伏消毒组（第五组）和空白组（第六组）。验证采用三种方法：十字形标记之间的距离和角度、叠加导板后的变形以及虚拟种植体的位移和轴向变化：消毒灭菌后，高压灭菌组和碘伏组的导板颜色变化更明显，高压灭菌组的导板有明显裂纹。H2O2组、戊二醛组、高压灭菌组和碘伏组的导板叠加后的变形以及十字形标记之间的距离和角度都有更明显的变化。第一至第五组导板的平均唇侧变形值（毫米）分别为 0.283、0.172、0.289、0.153 和 0.188。在虚拟种植体的位移和轴向变化方面，所有组与空白组都有统计学差异（P 结论：所有手术导板的位移和轴向变化都与空白组不同：几乎所有手术导板的尺寸在消毒和灭菌处理后都发生了变化，且存在组间差异。等离子消毒更适合用于手术导板消毒，因为处理后的变形较小。

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引用次数: 0

Prospective observational cohort study of the change of the marginal bone crest in relation to the prosthetic abutment height and the peri-implant vertical mucosal thickness at implants positioned subcrestally 前瞻性队列观察研究：边缘骨嵴的变化与修复基台高度和种植体周围垂直粘膜厚度的关系。

IF 3.7 2区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Clinical Implant Dentistry and Related Research

Pub Date : 2024-05-29 DOI: 10.1111/cid.13347

Serafín Maza-Solano DDS, María Baus-Domínguez DDS, Manuel-María Romero-Ruíz DMD, PhD, Aida Gutiérrez-Corrales DDS, PhD, Daniel Torres-Lagares DDS, PhD, María-Ángeles Serrera-Figallo DDS, PhD

Aim

To evaluate the influence on peri-implant crestal bone loss exerted by the vertical mucosal thickness and the abutment height over 12 months after placement of the restoration on subcrestal implants with change of platform, using a restoration abutment platform smaller than the implant platform.

Materials and Methods

A total of 99 implants were rehabilitated in the maxillary and mandibular posterior regions. A total of 22 implants were rehabilitated in the maxilla and 77 implants in the mandible, using digitally designed customized abutments with Atlantis weborder software, from the commercial house Dentsply Sirona (Dentsply Sirona S.A., Barcelona, Spain), version 4.6.5, adapting the height to the vertical thickness of the mucosa. Clinical and radiographic monitoring begins during the surgical procedure of placement of the implant and ends 12 months afterwards. Crestal bone loss was evaluated through the Carestream® CS8100 3D radiographic equipment.

Results

In all cases, the greatest loss of marginal bone occurred between the day of surgery (Tx) and placement of the rehabilitation (To). The average bone loss between both times was greater when the abutment height and vertical mucosal thickness did not exceed 3 mm. Subsequently, bone loss slowed and stabilized at 12 months.

Conclusions

The minimum abutment height and the vertical mucosal thickness are factors to take into account when minimizing peri-implant marginal bone loss, the abutment height having the greatest importance according to the clinical data obtained.

目的：使用小于种植体平台的修复基台，评估种植体平台下种植体修复后 12 个月内垂直粘膜厚度和基台高度对种植体周围骨质流失的影响：在上颌和下颌后牙区共修复了 99 个种植体。上颌共修复了22颗种植体，下颌共修复了77颗种植体，使用的是Dentsply Sirona公司（Dentsply Sirona S.A.，西班牙巴塞罗那）的Atlantis weborder软件（4.6.5版），根据粘膜的垂直厚度调整高度。临床和放射学监测从植入种植体的手术过程中开始，12 个月后结束。通过 Carestream® CS8100 3D X 射线设备评估嵴状骨损失：结果：在所有病例中，边缘骨的最大损失发生在手术当天（Tx）和植入修复体当天（To）之间。当基台高度和垂直粘膜厚度不超过 3 毫米时，这两个时间段的平均骨量损失较大。随后，骨质流失减缓，并在12个月时趋于稳定：结论：最小基台高度和垂直粘膜厚度是减少种植体周围边缘骨质流失时需要考虑的因素，根据临床数据，基台高度最为重要。

{"title":"Prospective observational cohort study of the change of the marginal bone crest in relation to the prosthetic abutment height and the peri-implant vertical mucosal thickness at implants positioned subcrestally","authors":"Serafín Maza-Solano DDS, María Baus-Domínguez DDS, Manuel-María Romero-Ruíz DMD, PhD, Aida Gutiérrez-Corrales DDS, PhD, Daniel Torres-Lagares DDS, PhD, María-Ángeles Serrera-Figallo DDS, PhD","doi":"10.1111/cid.13347","DOIUrl":"10.1111/cid.13347","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>To evaluate the influence on peri-implant crestal bone loss exerted by the vertical mucosal thickness and the abutment height over 12 months after placement of the restoration on subcrestal implants with change of platform, using a restoration abutment platform smaller than the implant platform.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>A total of 99 implants were rehabilitated in the maxillary and mandibular posterior regions. A total of 22 implants were rehabilitated in the maxilla and 77 implants in the mandible, using digitally designed customized abutments with Atlantis weborder software, from the commercial house Dentsply Sirona (Dentsply Sirona S.A., Barcelona, Spain), version 4.6.5, adapting the height to the vertical thickness of the mucosa. Clinical and radiographic monitoring begins during the surgical procedure of placement of the implant and ends 12 months afterwards. Crestal bone loss was evaluated through the Carestream® CS8100 3D radiographic equipment.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>In all cases, the greatest loss of marginal bone occurred between the day of surgery (Tx) and placement of the rehabilitation (To). The average bone loss between both times was greater when the abutment height and vertical mucosal thickness did not exceed 3 mm. Subsequently, bone loss slowed and stabilized at 12 months.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The minimum abutment height and the vertical mucosal thickness are factors to take into account when minimizing peri-implant marginal bone loss, the abutment height having the greatest importance according to the clinical data obtained.</p>\u0000 </section>\u0000 </div>","PeriodicalId":50679,"journal":{"name":"Clinical Implant Dentistry and Related Research","volume":"26 4","pages":"750-762"},"PeriodicalIF":3.7,"publicationDate":"2024-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cid.13347","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141162972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Static and dynamic guided bone regeneration using a shape-memory polyethylene terephthalate membrane: An experimental study in rabbit mandible 使用形状记忆聚对苯二甲酸乙二醇酯膜进行静态和动态引导骨再生：兔下颌骨实验研究。

IF 3.7 2区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Clinical Implant Dentistry and Related Research

Pub Date : 2024-05-28 DOI: 10.1111/cid.13337

Kazuhiro Imoto, Karen Hoshi, Kenji Odashima, Shinnosuke Nogami, Hidero Unuma, Kensuke Yamauchi

Background

Periosteal expansion (PEO) results in the formation of new bone in the space created between existing bone by expanding the periosteum. PEO has already been performed on rabbit parietal bone and effective new bone formation has been demonstrated. In this study, the utility of a polyethylene terephthalate (PET) membrane as an activator was evaluated in the more complex morphology of the mandible.

Methods

A PET membrane coated with hydroxyapatite (HA)/gelatine was placed in the rabbit mandibular bone at lower margin of mandibular molar region underneath periosteum, and screw-fixed. In the experimental group, the membrane was bent and screw-fixed along the lateral surface of the bone, with removal of the outer screw after 7 days followed by activation of the membrane. The experimental group was divided into two subgroups: with and without a waiting period for activation. Three animals were euthanized at 3 weeks and another three at 5 weeks postoperatively. Bone formation was assessed using micro-CT as well as histomorphometric and histological methods.

Results

No PET membrane-related complications were observed. The area of newly formed bone and the percentage of new bone in the space created by the stretched periosteum did not significantly differ between the control and experimental groups. However, in the experimental group a greater volume was present after 5 weeks than after 3 weeks. Histologically, bone formation occurred close to the site of cortical bone perforation, with many sinusoidal vessels extending through the perforations in the new bone into the overlying fibrous tissue. Inflammatory cells were not seen in the bone.

背景：骨膜扩张术（PEO）通过扩张骨膜，在现有骨骼之间形成新的骨骼。已在兔顶骨上进行了 PEO 试验，并证明能有效形成新骨。本研究评估了聚对苯二甲酸乙二醇酯（PET）膜作为激活剂在形态更为复杂的下颌骨中的效用：方法：将涂有羟基磷灰石（HA）/明胶的 PET 膜置于兔下颌骨，位于下颌磨牙区下缘骨膜下方，并用螺钉固定。在实验组中，将骨膜弯曲并沿骨的外侧表面用螺钉固定，7 天后取下外侧螺钉，然后激活骨膜。实验组分为两个亚组：有等待激活期和无等待激活期。三只动物在术后 3 周安乐死，另外三只在术后 5 周安乐死。使用显微 CT 以及组织形态学和组织学方法对骨形成进行评估：结果：未观察到 PET 膜相关并发症。对照组和实验组新形成骨的面积以及拉伸骨膜形成的空间中新骨的百分比没有显著差异。不过，实验组在 5 周后出现的骨量大于 3 周后。从组织学角度看，骨形成发生在皮质骨穿孔部位附近，许多窦状血管通过新骨穿孔延伸到上覆的纤维组织中。骨中未见炎性细胞。

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引用次数: 0

Tissue changes around dental implants installed in alveolar ridge preservation sites: A 1-year follow-up randomized controlled clinical trial 牙槽嵴保留区种植体周围组织的变化：为期 1 年的随机对照临床试验。

IF 3.7 2区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Clinical Implant Dentistry and Related Research

Pub Date : 2024-05-28 DOI: 10.1111/cid.13348

Eran Gabay DMD, PhD, Eli Regev DMD, Yaniv Mayer DMD, Jacob Horwitz DMD, Thabet Asbi DMD, Ofir Ginesin DMD, Hadar Zigdon-Giladi DMD, PhD

Objective

This study aimed to assess radiographic marginal bone changes 22 months post extraction, which is 1 year after implant loading in alveolar ridge preservation (ARP) sites grafted with a combination of collagen-embedded xenogenic bone substitute (DBBM-C) and collagen matrix (CMX), comparing them with implants placed in naturally healed sites.

Methods

This randomized controlled clinical trial was conducted over 22 months. Patients who needed a single tooth extraction and subsequent implant placement in nonmolar areas were enrolled. The test group received deproteinized bovine bone mineral with 10% collagen covered by a procaine collagen membrane, while the control group allowed spontaneous healing. Radiographic bone level changes were documented using periapical radiographs at implant placement and follow-up visits (6, 10, and 22 months postextraction). Early implant soft tissue exposure, clinical parameters, and patient-reported outcomes were recorded.

Results

Twenty-two out of 28 participants completed a 22-month follow-up, 9 in the test group and 13 in the control group. At 10-month postextraction follow-up, the mean MBL was 1.01 ± 1.04 mm in the treatment group and 0.81 ± 0.93 mm in the control group (p = 0.804). At 22 months, the mean MBL was 2.09 ± 1.03 mm in the treatment group and 1.58 ± 0.73 mm in the control group (p = 0.339). No statistically significant differences in probing depth (PD) and bleeding on probing (BOP) were found at the 22 -month follow-up as well. Soft tissue mean recession was observed in the control group (0.36 ± 0.84 mm), while no recession was found in the test group (p = 0.2). Early implant soft tissue exposure occurred in 33% of test group participants, while none was observed in the control group (p = 0.047).

Conclusion

One year after implant loading, no significant differences in marginal bone resorption were found between implants placed in ARP-treated and naturally healed sites. However, ARP-treated sites exhibited early implant soft-tissue exposure, suggesting a possible impairment in soft tissue healing.

研究目的本研究旨在评估拔牙后 22 个月，即种植体植入牙槽嵴保留（ARP）部位 1 年后的放射学边缘骨变化，并将其与自然愈合部位的种植体进行比较：这项随机对照临床试验为期 22 个月。方法：这项随机对照临床试验历时 22 个月，研究对象为需要拔除单颗牙齿并随后在非磨牙区植入种植体的患者。试验组接受含有 10%胶原蛋白的去蛋白牛骨矿物质，并覆盖一层普鲁卡因胶原蛋白膜，而对照组则允许自然愈合。在植入种植体和随访（拔牙后 6 个月、10 个月和 22 个月）时，使用根尖周X光片记录骨水平的变化。记录早期种植体软组织暴露情况、临床参数和患者报告结果：28 名参与者中有 22 人完成了 22 个月的随访，其中试验组 9 人，对照组 13 人。在拔牙后 10 个月的随访中，治疗组的平均 MBL 为 1.01 ± 1.04 毫米，对照组为 0.81 ± 0.93 毫米（p = 0.804）。22 个月时，治疗组的平均 MBL 为 2.09 ± 1.03 毫米，对照组为 1.58 ± 0.73 毫米（p = 0.339）。在 22 个月的随访中，探诊深度 (PD) 和探诊出血量 (BOP) 也没有发现明显的统计学差异。对照组观察到软组织平均后退（0.36 ± 0.84 mm），而试验组未发现后退（p = 0.2）。33% 的测试组参与者出现了早期种植体软组织暴露，而对照组则没有（p = 0.047）：结论：种植体植入一年后，ARP 处理过的种植体与自然愈合的种植体在边缘骨吸收方面没有明显差异。不过，ARP 处理过的部位会出现早期种植体软组织暴露，这表明软组织愈合可能会受到影响。

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引用次数: 0