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Clinical Implant Dentistry and Related Research最新文献

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History of periodontitis as a risk factor for implant failure and incidence of peri-implantitis: A systematic review, meta-analysis, and trial sequential analysis of prospective cohort studies 牙周炎病史是种植失败和种植体周围炎发病率的风险因素:前瞻性队列研究的系统回顾、荟萃分析和试验序列分析。
IF 3.7 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-05-08 DOI: 10.1111/cid.13330
Matteo Serroni, Wenche S. Borgnakke, Luigi Romano, Giuseppe Balice, Michele Paolantonio, Muhammad H. A. Saleh, Andrea Ravidà

Introduction

Dental implants are widely employed as dependable replacements for lost teeth. However, it is crucial to establish, solely through prospective cohort studies, whether a history of periodontitis indeed constitutes a significant risk factor for implant failure.

Methods

A systematic literature search was conducted in October 2022 in several electronic databases with subsequent manual updates. Only original prospective cohort studies evaluating the implant (loss) rate ≥1 year after implant loading were included. Logarithmic risk ratio and weighted mean differences were calculated. Study results were summarized using random effects meta-analyses evaluated by trial sequential analyses. The Newcastle-Ottawa scale evaluated study bias and the GRADE approach assessed the certainty/quality of the evidence.

Results

A total of 14 publications reporting on 12 prospective cohort studies were included. Low evidence certainty/quality evidence due to the absence of randomized clinical trials revealed significantly greater odds of failure in patients with a history of periodontitis at follow-ups both after ≤5 years (RR = 1.62; 95% CI: 1.71–2.37; p = 0.013) and >5 years (RR = 2.26; 95% CI: 1.12–4.53; p = 0.023). The incidence of peri-implantitis (RR = 4.09; 95% CI: 1.93–8.58; p < 0.001) and the weighted mean (WM) of marginal bone loss (WM difference = 0.75 mm; 95% CI: 0.18–1.31; p < 0.05) were statistically significantly greater in the periodontally compromised group, whereas there was no significant difference between the two groups for peri-implant probing depth.

Conclusion

A history of periodontitis can be considered a significant risk factor for incident implant failure, peri-implantitis, and greater marginal bone loss.

简介种植牙作为失牙的可靠替代物被广泛使用。然而,仅通过前瞻性队列研究来确定牙周炎病史是否确实是导致种植失败的重要风险因素至关重要:方法:2022 年 10 月,我们在多个电子数据库中进行了系统性文献检索,并随后进行了人工更新。方法:2022 年 10 月,在多个电子数据库中进行了系统性文献检索,并进行了人工更新。仅纳入了评估种植体植入≥1 年后种植体(脱落)率的原始前瞻性队列研究。计算对数风险比和加权平均差。研究结果采用随机效应荟萃分析法进行总结,并通过试验序列分析法进行评估。纽卡斯尔-渥太华量表评估了研究偏倚,GRADE方法评估了证据的确定性/质量:结果:共纳入了 14 篇出版物,报告了 12 项前瞻性队列研究。由于缺乏随机临床试验,证据的确定性/质量较低,结果显示,有牙周炎病史的患者在随访≤5年(OR = 1.65; 95% CI: 1.12-2.44; p = 0.012)和>5年(OR = 2.36; 95% CI: 1.13-4.95; p = 0.023)后失败的几率明显更高。种植体周围炎的发生率(OR = 5.93;95% CI:2.75-12.8;P 结论:牙周炎病史可能会导致种植体周围炎:牙周炎病史可被视为种植失败、种植体周围炎和边缘骨质流失的重要风险因素。
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引用次数: 0
Clinical and radiographic performance of late placed and early loaded dental implants with a conditioned hydrophilic surface in posterior mandible sites: A prospective case series with an 8.5- to 9.5-year follow-up 在下颌后部植入具有条件亲水性表面的晚植入和早植入牙科植入体的临床和放射学表现:前瞻性病例系列,随访 8.5 至 9.5 年。
IF 3.7 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-05-06 DOI: 10.1111/cid.13333
Pedro Molinero-Mourelle, Martin Schimmel, Fiona Alena Forrer, Stefan Paul Hicklin, Clemens Raabe, Vivianne Chappuis, Manrique Fonseca

Objective

To assess the clinical outcomes by means of implant and prosthetic survival of late placed and early loaded implants with a hydrophilic, moderately rough surface for partially edentulous patients after a follow-up of 8.5 to 9.5 years.

Materials and methods

A prospective case series study involving 15 patients with single, late placed and early loaded implants in the posterior mandible was performed. Clinical and radiographical parameters, including biological and technical complications and patient satisfaction, were assessed.

Results

From an initial sample of 15 patients, 12 were included. A total of 16 implants were observed. After a mean follow-up of 9 years and 7 months (SD ± 3.8 months), implant success and survival rate were 100%. The prosthetic survival rate was 100%, and the prosthetic success rate was 93.8% since a major chipping was observed. No biological complications were observed, and the mean modified plaque index was 0.03 (SD ± 0.09) with a mean probing pocket depth of 2.95 mm (SD ± 0.09). A mean marginal bone level (MBL) of 0.04 mm (SD ± 0.88) and a mean VAS of 9.42 (SD ± 0.90) for patient satisfaction were recorded.

Conclusion

Late placed and early loaded implants with a moderately rough endosseal surface are a reliable option for rehabilitating partially edentulous patients. An implant survival rate of 100% and a prosthodontic success rate of 93.8% were observed. Patient satisfaction scores were high and peri-implant hard and soft tissues remained healthy. The study findings should be carefully interpreted because of the small sample.

目的通过对部分无牙颌患者进行 8.5 至 9.5 年的随访,评估亲水性适度粗糙表面的晚期植入和早期植入种植体的临床疗效:这是一项前瞻性病例系列研究,涉及 15 名下颌后部植入单个晚期和早期种植体的患者。研究评估了临床和放射学参数,包括生物学和技术并发症以及患者满意度:结果:从最初的 15 名患者中抽取了 12 名。结果:在最初的 15 名患者样本中,有 12 名患者被纳入其中,共观察到 16 个种植体。经过平均 9 年零 7 个月(SD ± 3.8 个月)的随访,种植体成功率和存活率均为 100%。修复体存活率为 100%,修复体成功率为 93.8%,因为观察到了严重的崩裂。未观察到生物学并发症,平均改良斑块指数为 0.03(SD ± 0.09),平均探诊袋深度为 2.95 毫米(SD ± 0.09)。平均边缘骨水平(MBL)为 0.04 mm(SD ± 0.88),患者满意度平均 VAS 为 9.42(SD ± 0.90):结论:对于部分无牙颌患者来说,晚期植入、早期加载、具有适度粗糙骨内表面的种植体是一种可靠的康复选择。种植体存活率为 100%,修复成功率为 93.8%。患者的满意度很高,种植体周围的软硬组织保持健康。由于样本较少,因此应谨慎解释研究结果。
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引用次数: 0
25 years of Clinical Implant Dentistry and Related Research (CIDRR): A modern bibliometric and Altmetrics network analysis 临床种植牙及相关研究(CIDRR)25 年:现代文献计量学和 Altmetrics 网络分析。
IF 3.7 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-05-06 DOI: 10.1111/cid.13335
Hamoun Sabri DMD, PgC, Paolo Nava DDS, Shayan Barootchi DMD, MS, Lorenzo Tavelli DDS, MS, PhD, Alberto Monje DDS, MS, PhD, José Nart DDS, PhD, Hom-Lay Wang DDS, MSD, PhD, Muhammad H. A. Saleh BDS, MDS
<div> <section> <h3> Introduction</h3> <p>Since its establishment in 1999, the journal of <i>Clinical Implant Dentistry and Related Research</i> (CIDRR) has consistently disseminated notable clinical and translational research within the domain of oral implantology. As the journal approaches its milestone 25th anniversary, this study endeavors to systematically delineate the publication trends, level of evidence, and bibliometric indices characterizing the initial quarter-century of CIDRR's scholarly activity. Notably, the investigation adopts a contemporary methodology by incorporating Altmetric analysis, thereby enriching the evaluation with an assessment of the broader societal and online impact of the published research.</p> </section> <section> <h3> Methods</h3> <p>A comprehensive search was performed in SCOPUS and PubMed to access the bibliographic data of all articles published in the journal from 1999 to 2024. Additionally, Altmetric database was used to obtain social media attention scores (AAS). Journal's overall performance via impact factor and quartile range was assessed. Most cited papers were identified and the most prolific authors, institutions and countries and the collaboration networks among those were assessed. The level of evidence of all articles was determined based on Oxford level of evidence scale. All articles were categorized based on their major topic in the field of implant dentistry.</p> </section> <section> <h3> Results</h3> <p>Throughout its first 25 years of activity, CIDRR published 1912 articles with an annual growth rate of 2.67% and consistently being ranked at Q1 quartile in “Dentistry (miscellaneous)” and “Oral Surgery” journal categories. When clinical studies are considered, level I and II evidence constituted 22.82% and 11.82% of all articles, respectively. Sweden, the USA, and Italy as well as Göteborgs Universitet, Sahlgrenska Akademin. and Malmö Högskola were the most prolific countries and institutions respectively. “Implant system/design/characteristics,” “Bone Augmentation,” and “Implant Prosthesis” were the top most investigated topics.</p> </section> <section> <h3> Conclusions</h3> <p>The examination of the journal's initial 25 years highlighted that CIDRR has surpassed similar dental research journals in publishing a greater number of high-level evidence articles. It also showcased diverse country- and author-collaboration networks. However, the journal's social media presence is still evolving. This article, presenting a comprehensive overview of the journal's scientometric and bibliographic acti
引言:自 1999 年创刊以来,《临床种植牙及相关研究》(CIDRR)杂志一直致力于传播口腔种植领域内著名的临床和转化研究成果。在该杂志即将迎来具有里程碑意义的 25 周年之际,本研究试图系统地描述 CIDRR 最初四分之一个世纪学术活动的发表趋势、证据水平和文献计量指数。值得注意的是,这项调查采用了现代方法,纳入了 Altmetric 分析,从而通过评估已发表研究的更广泛社会和网络影响来丰富评估内容:方法:在 SCOPUS 和 PubMed 中进行了全面搜索,以获取 1999 年至 2024 年期间该期刊发表的所有文章的书目数据。此外,还使用 Altmetric 数据库获取社会媒体关注度得分(AAS)。通过影响因子和四分位数范围评估期刊的整体表现。确定了被引用次数最多的论文,并评估了最多产的作者、机构和国家以及这些机构和国家之间的合作网络。根据牛津证据等级表确定所有文章的证据等级。所有文章都根据其在种植牙领域的主要课题进行了分类:在其最初 25 年的活动中,CIDRR 共发表了 1912 篇文章,年增长率为 2.67%,在 "牙科(杂项)"和 "口腔外科 "期刊类别中一直排名第一。如果考虑到临床研究,I 级和 II 级证据分别占所有文章的 22.82% 和 11.82%。瑞典、美国和意大利以及哥德堡大学、萨尔格伦斯卡学院和马尔默高等专科学校分别是发表文章最多的国家和机构。"植入系统/设计/特点"、"骨增量 "和 "植入假体 "是调查最多的主题:对该期刊最初 25 年的研究表明,CIDRR 在发表更多高水平的实证文章方面已经超越了同类牙科研究期刊。它还展示了多样化的国家和作者合作网络。然而,该期刊的社交媒体仍在不断发展。这篇文章全面概述了该期刊的科学计量学和文献学活动,为研究人员、临床医生和利益相关者提供了宝贵的参考,从传统和现代的角度提供了见解。
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引用次数: 0
Immediate versus early loading of immediately placed bone-level tapered dental implants with hydrophilic surface in full arch maxillary rehabilitation: A pilot randomized clinical trial with 2-year follow-up 在上颌全弓康复中,立即植入带亲水性表面的骨水平锥形种植体与提前植入种植体的比较:一项为期两年的随机临床试验
IF 3.7 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-05-01 DOI: 10.1111/cid.13334
Aleksa Marković, Ana Todorović, Mirko Glišić, Jovana Marković, Branislav Ilić, Bojan Janjić, Tijana Mišić, Branka Trifković, Uroš Vučić, Miodrag Šćepanović, Michel M. Dard

This study aimed to compare implant stabilities between the immediate and early loaded, immediately placed bone-level tapered dental implants in the maxilla and to evaluate marginal bone loss (MBL), oral health-related quality of life (OHRQoL), and patient satisfaction at a 2-year follow-up. A pilot, prospective, randomized, controlled clinical trial was conducted on 24 maxillary failing dentition patients. The bone-level tapered implants of 12 patients were immediately loaded with temporary restorations, while the other 12 patients did not receive any kind of temporization. Implant-supported screw-retained complete porcelain-fused-to-metal prostheses were delivered to all patients in the seventh postoperative week. The insertion torque values of implants assigned to the immediate and early loading groups were 33.0 ± 4.87 and 29.26 ± 8.31 Ncm, respectively. The dynamics of implant stability changes from implant placement up to a 2-year follow-up were similar for both groups (Penguin®, p = 0.268; Ostell®, p = 0.552), while the MBL was at submillimeter level. The cumulative implant survival rate was 91.80% for immediately loaded implants and 97.22% for early loaded implants, without significant difference (p = 0.162). The total score on the Oral Health Impact Profile questionnaire significantly decreased over time in both groups, indicating improvement in OHRQoL (p < 0.001), and the high level of patient satisfaction remained after 2 years of function regardless of a loading protocol. Both loading protocols, immediate and early, of six immediately placed bone-level tapered dental implants are an adequate treatment choice for fixed rehabilitation of the maxillary failing dentition.

本研究旨在比较上颌即刻植入和早期植入、即刻植入骨水平锥形牙种植体之间的种植体稳定性,并评估两年随访期间的边缘骨损失(MBL)、口腔健康相关生活质量(OHRQoL)和患者满意度。我们对 24 名上颌失败牙患者进行了试点、前瞻性、随机对照临床试验。其中 12 名患者的骨水平锥形种植体立即装上了临时修复体,而另外 12 名患者没有接受任何形式的临时修复。所有患者都在术后第 7 周接受了种植体支持螺钉固位的全瓷融合金属修复体。即刻加载组和早期加载组的种植体植入扭矩值分别为(33.0 ± 4.87)和(29.26 ± 8.31)Ncm。从种植体植入到两年随访期间,两组的种植体稳定性变化动态相似(Penguin®,p = 0.268;Ostell®,p = 0.552),而 MBL 处于亚毫米水平。即刻植入种植体的累积存活率为 91.80%,早期植入种植体的累积存活率为 97.22%,无显著差异(p = 0.162)。随着时间的推移,两组患者的口腔健康影响档案问卷总分均显著下降,表明患者的口腔健康质量生活得到了改善(p <0.001)。六颗即刻植入的骨水平锥形牙种植体的即刻植入和早期植入两种植入方案都是上颌失败牙固定修复的适当治疗选择。
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引用次数: 0
Effects of sterilization, conditioning, and thermal aging on the retention of zirconia hybrid abutments: A laboratory study 消毒、调理和热老化对氧化锆混合基台固位的影响:实验室研究
IF 3.7 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-04-29 DOI: 10.1111/cid.13332
Nalah Alghanaim, Matthias Kern, Christine Yazigi, M. Sad Chaar

Objective

To investigate the effects of sterilization, conditioning method, and thermal aging on the retentive strength of two-piece zirconia abutments.

Materials and Methods

In total, 128 stock zirconia abutments were divided into four groups (n = 32) according to the conditioning parameters: (A) air-abrasion using 50 μm alumina particles/1.0 bar, (B) 50 μm/2.0 bar, (C) 100 μm/1.0 bar, and (D) 100 μm/2.0 bar. All abutments were bonded onto titanium bases using DTK adhesive resin and stored in water bath (37°C) for 72 h. Each group was subdivided into two subgroups (n = 16), group 1 was disinfected, whereas group 2 followed disinfection and autoclave sterilization. Half of the specimens of each subgroup (n&amp;#x02009;=&amp;#x02009;8) was directly subjected to the axial retention test (groups N), while the other half was first subjected to 150&amp;#x02009;days of thermocycling followed by retention test (groups T). Statistical analysis was performed with three-way ANOVA, additional statistical analysis was performed by using separate one-way ANOVAs followed by the Tukey's post-hoc test for post hoc pairwise comparisons among groups.

Results

The highest median retention strength was recorded for group B2N (1390 N), whereas the lowest strength was recorded for group C1T (688 N). No significant interaction (p ≥ 0.05) was detected between the different variables; conditioning method, sterilization, and the thermal cycling regarding the effect on the resulting retention. However, the sterilization always showed a positive effect. Thermocycling presented an adversely significant effect only in the absence of sterilization (p < 0.05), with the exception of subgroups A. For the sterilized groups, thermocycling had no statistically significant effect on the retention.

Conclusion

Steam autoclaving increased the retention of hybrid zirconia abutments. DTK adhesive resin for two-piece zirconia abutments performed well after sterilization and thermocycling.

材料和方法将 128 个氧化锆基台按照调理参数分为四组(n = 32):(A) 使用 50 μm 氧化铝颗粒/1.0 bar 空磨,(B) 50 μm/2.0 bar 空磨,(C) 100 μm/1.0 bar 空磨,(D) 100 μm/2.0 bar 空磨。所有基台都使用 DTK 粘接树脂粘接在钛基台上,并在水浴(37°C)中保存 72 小时。每组又分为两个亚组(n = 16),第 1 组进行消毒,第 2 组进行消毒和高压灭菌。每个子组的一半样本(n&amp;#x02009;=&amp;#x02009;8)直接进行轴向保留试验(N 组),另一半样本先进行 150&amp;#x02009;d 的热循环,然后进行保留试验(T 组)。统计分析采用三因素方差分析,其他统计分析采用单独的单因素方差分析,然后采用 Tukey's 事后检验进行组间配对比较。结果 B2N 组的中位保留强度最高(1390 N),而 C1T 组的中位保留强度最低(688 N)。在不同变量(调节方法、灭菌和热循环)对所产生的保持力的影响方面,没有发现明显的交互作用(p ≥ 0.05)。然而,灭菌总是显示出积极的影响。结论蒸汽高压灭菌提高了混合氧化锆基台的固位力。用于两件式氧化锆基台的 DTK 粘接树脂在灭菌和热循环后表现良好。
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引用次数: 0
Half- and full-grafting alveolar ridge preservation with different sealing materials: A three-arm randomized clinical trial 采用不同密封材料的半移植和全移植牙槽嵴保存术:三臂随机临床试验
IF 3.7 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-04-18 DOI: 10.1111/cid.13327
Cho-Ying Lin, Meng-Yao Chiu, Pe-Yi Kuo, Hom-Lay Wang
<div> <section> <h3> Objective</h3> <p>The objective of this study is to investigate the effect of different alveolar ridge preservation (ARP) approaches on bone resorption and their potential for facilitating implant placement.</p> </section> <section> <h3> Materials and methods</h3> <p>Patients who underwent one or two tooth extractions with a desire for restoration were included in the study. The participants were randomly assigned to one of three groups for ARP. The groups were as follows: (1) Half grafting of bovine bone mineral (DBBM-C) covered with non-resorbable dense polytetrafluoroethylene (dPTFE) membrane (Test 1 group); (2) Half grafting of bovine bone mineral (DBBM-C) covered with collagen membrane (Test 2 group); and (3) Full grafting with collagen membrane (DBBM-C + Collagen membrane) as the Control group. After 6-month healing period, the evaluation encompassed clinical, radiographic, implant-related outcomes, and the factors contributing to hard and soft tissue alterations.</p> </section> <section> <h3> Results</h3> <p>Enrollment in this study comprised 56 patients. At the 6-month follow-up, radiographic analysis in computed beam computed tomography images was conducted for 18, 19, and 19 patients with 18, 20, and 20 tooth sites in Test 1, Test 2, and Control groups, respectively. Additionally, a total of 15, 17, and 17 patients with 15, 18, and 17 implants were evaluated. Based on radiographic analysis, all groups showed limited ridge resorption at 1 mm from crest horizontally (Test 1: 1.29 ± 1.37; Test 2: 1.07 ± 1.07; Control: 1.54 ± 1.33 mm, <i>p</i> = 0.328), while the Control group showed greater radiographic bone height gain in mid-crestal part vertically (Test 1: 0.11 ± 1.02; Test 2: 0.29 ± 0.83; Control: −0.46 ± 0.95 mm, <i>p</i> = 0.032). There were no significant intergroup differences in terms of keratinized mucosal width, bone density, insertion torque, and the need of additional bone graft. However, the use of a dPTFE membrane resulted in a significantly higher vertical mucosal thickness (Test 1: 2.67 ± 0.90; Test 2: 3.89 ± 1.08; Control: 2.41 ± 0.51 mm, <i>p</i> < 0.001).</p> </section> <section> <h3> Conclusions</h3> <p>The study showed comparable dimensional preservation with limited vertical shrinkage, while thin buccal bone plate, non-molar sites, and large discrepancy between buccal and palatal/lingual height may contribute to greater shrinkage. Thicker mucosa with dPTFE membrane required further investigation for interpretation.</p> </section> <section> <h3> Clinical trial registration number</h3> <p>NCT06049823
本研究旨在探讨不同牙槽嵴保留(ARP)方法对骨吸收的影响及其促进种植体植入的潜力。参与者被随机分配到三个组中的一组进行 ARP。组别如下(1) 牛骨矿物质(DBBM-C)半移植,覆盖不可吸收的致密聚四氟乙烯(dPTFE)膜(试验 1 组);(2) 牛骨矿物质(DBBM-C)半移植,覆盖胶原蛋白膜(试验 2 组);(3) 胶原蛋白膜全移植(DBBM-C + 胶原蛋白膜),作为对照组。经过 6 个月的愈合期后,评估内容包括临床、影像学、种植体相关结果以及导致软硬组织改变的因素。在 6 个月的随访中,分别对试验 1 组、试验 2 组和对照组的 18、19 和 19 名患者的 18、20 和 20 个牙位进行了计算机断层扫描图像的放射学分析。此外,共对 15、17 和 17 名患者的 15、18 和 17 个种植体进行了评估。根据影像学分析,所有组别在水平方向距牙冠 1 毫米处都显示出有限的牙脊吸收(试验 1:1.29 ± 1.37;试验 2:1.07 ± 1.07;对照组:1.54 ± 1.33 毫米,p = 0.328),而对照组在垂直方向的牙冠中段显示出更大的影像学骨高度增加(试验 1:0.11 ± 1.02;试验 2:0.29 ± 0.83;对照组:-0.46 ± 0.95):-0.46±0.95毫米,P = 0.032)。在角化粘膜宽度、骨密度、插入扭矩和是否需要额外植骨方面,组间差异不明显。然而,使用 dPTFE 膜导致粘膜垂直厚度明显增加(试验 1:2.67 ± 0.90;试验 2:3.89 ± 1.08;对照组:2.41 ± 0.51 mm,p < 0.001)。使用 dPTFE 膜的较厚粘膜需要进一步研究才能解释。该临床试验在参与者招募和随机化之前未注册。
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引用次数: 0
Featured Cover 精选封面
IF 3.6 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-04-07 DOI: 10.1111/cid.13329
Rubén Davó MD, PhD, Shengchi Fan DDS, MS, Feng Wang DDS, MD, Yiqun Wu DDS, MD

The cover image is based on the Original Article Long-term survival and complications of Quad Zygoma Protocol with Anatomy-Guided Approach in severely atrophic maxilla: A retrospective follow-up analysis of up to 17 years by Rubén Davó MD et al., https://doi.org/10.1111/cid.13296.

封面图片根据 Rubén Davó MD 等人的原创文章《严重萎缩上颌骨的 Quad Zygoma 方案与解剖引导方法的长期存活率和并发症:长达 17 年的回顾性随访分析》制作,https://doi.org/10.1111/cid.13296.
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引用次数: 0
Featured Cover 精选封面
IF 3.6 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-04-07 DOI: 10.1111/cid.13328
Chun Yi DMD, Xi Jiang DMD, Ping Di DMD, Shuxin Ren DMD, Ye Lin DMD

The cover image is based on the Original Article The facial–coronal ridge crest alterations after single immediate implant placement and provisionalization with thin buccal plate phenotype in anterior maxilla: A radiographic case-series study by Chun Yi DMD et al., https://doi.org/10.1111/cid.13280.

封面图片来自 Chun Yi DMD 等人的原创文章《上颌骨前部单个即刻种植体植入和薄颊板表型临时处理后的面部-冠状脊嵴改变:一项放射学病例系列研究》,https://doi.org/10.1111/cid.13280。
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引用次数: 0
Allergic reaction of poly-ether-ether-ketone versus titanium implants: A posttest-only control group design experimental study using a rabbit model 聚醚醚酮与钛植入物的过敏反应:以兔子为模型进行的纯试验后对照组设计实验研究
IF 3.7 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-04-04 DOI: 10.1111/cid.13323
Tamer Hamed Hassan, Nabeel Ayappali Kalluvalappil

Purpose

The aim of this study was to determine clinically and genetically the allergic effects of titanium and poly-ether-ether-ketone (PEEK) implants following loading in rabbit tibias.

Materials and methods

This study included 18 white New Zealand male rabbits (n = 18) divided evenly into three groups: control, titanium (Ti), and PEEK (P). Clinically, the allergenic effect of titanium and PEEK was investigated by detecting the effect on lymph nodes. Furthermore, RT-PCR and ELISA were used to detect the expression of certain genes IL-6, TNF-α, OPG, RANKL, and RUNX-2 through both types of implants.

Results

Our findings demonstrated that titanium implants induced enlarged lymph nodes, which PEEK did not. Overall, RT-PCR and ELISA techniques revealed that Ti implants had higher expression of the inflammatory genes IL-6 and TNF-α. Ti had the highest expression in OPG findings, while PEEK had the lowest. RANKL expression was highest in the control group and lowest in the PEEK group. RUNX-2 is the highest for the control group and the lowest for the titanium group.

Conclusion

Although titanium implants elicited greater allergy responses than PEEK implants, titanium has the highest expression of bone formation genes and the lowest expression of bone resorption genes, making it preferable to PEEK.

本研究的目的是从临床和遗传学角度确定钛和聚醚醚酮(PEEK)植入物在兔胫骨装载后的过敏效应。材料和方法本研究包括 18 只白色新西兰雄兔(n = 18),平均分为三组:对照组、钛组(Ti)和 PEEK 组(P)。在临床上,通过检测对淋巴结的影响来研究钛和 PEEK 的过敏效应。此外,还使用 RT-PCR 和 ELISA 检测了两种植入物中某些基因 IL-6、TNF-α、OPG、RANKL 和 RUNX-2 的表达情况。总体而言,RT-PCR 和 ELISA 技术表明,钛种植体的炎症基因 IL-6 和 TNF-α 表达较高。在 OPG 的研究结果中,钛的表达量最高,而 PEEK 的表达量最低。对照组的 RANKL 表达最高,而 PEEK 组最低。RUNX-2在对照组中最高,而在钛组中最低。结论虽然钛种植体比 PEEK 种植体引起的过敏反应更大,但钛在骨形成基因中的表达量最高,而在骨吸收基因中的表达量最低,因此钛比 PEEK 更受青睐。
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引用次数: 0
Assessment of bone gain and neurosensory affection with the sandwich osteotomy technique for vertically deficient posterior mandible using a full digital workflow versus conventional protocol: A randomized split mouth study 采用全数字化工作流程与传统方案对比,评估三明治截骨术治疗垂直缺损后下颌骨的骨增量和神经感觉:随机分口研究。
IF 3.7 2区 医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2024-03-31 DOI: 10.1111/cid.13324
Ahmed K. Moussa BDS, Mohamed Shawky BDS, MSc, Lobna Abdel Aziz Aly PhD, Mohamed Mounir PhD, Waleed F. Esmael PhD

Background

Using the sandwich osteotomy technique in the posterior mandible is delicate. This study aimed to assess the safety and the amount of bone gain using a full digital workflow versus the conventional procedure.

Patients and methods

This split mouth study included 10 patients with bilateral vertically deficient posterior mandible. One side received conventional sandwich interpositional bone grafting (control group), while the other side received the same protocol using two patient-specific guides. The first guide (cutting guide) was used to place the osteotomies safely and accurately according to the predetermined dimensions and locations, and the second guide was used to fix the mobilized bony segment, leaving the desired gap to be filled with a particulate xenogenic bone graft.

Results

Full neurosensory recovery was documented at 2 months postoperative for all patients and bilaterally. After 4 months, there was a statistically significant difference in vertical bone gain between both groups (p = 0.001), measuring an average of 3.76 ± 0.72 mm in the study group and 2.69 ± 0.37 mm in the control group. No statistically significant difference was found between the planned vertical augmentation (3.85 ± 0.58 mm) and the obtained vertical bone gain (3.76 ± 0.72 mm) in the study group (p = 0.765) proving the accuracy of the guided procedure.

Conclusion

Computer-guided sandwich interpositional grafting is predictable regarding the execution of the osteotomies and the accuracy of fixation of the transport segment.

背景:在下颌后部使用三明治截骨技术是很微妙的。本研究旨在评估使用全数字化工作流程与传统手术的安全性和骨增量:这项分口研究包括10名双侧下颌后部垂直缺损的患者。一侧患者接受传统的三明治夹层植骨术(对照组),另一侧患者则使用两种患者专用的导板接受相同的方案。第一种导板(切割导板)用于按照预定的尺寸和位置安全准确地放置截骨,第二种导板用于固定被移动的骨段,留下所需的间隙,用颗粒状异种骨移植填充:结果:所有患者术后 2 个月双侧神经感觉完全恢复。4 个月后,两组患者的垂直骨增量差异有统计学意义(P = 0.001),研究组平均为 3.76 ± 0.72 mm,对照组平均为 2.69 ± 0.37 mm。研究组计划的垂直骨增量(3.85 ± 0.58 毫米)和获得的垂直骨增量(3.76 ± 0.72 毫米)之间没有明显的统计学差异(p = 0.765),证明了引导程序的准确性:结论:计算机引导下的三明治夹层植骨术在截骨的实施和运输段固定的准确性方面具有可预测性。
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引用次数: 0
期刊
Clinical Implant Dentistry and Related Research
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