Clinical Journal of the American Society of Nephrology最新文献

{"title":"Effect of Remote and Virtual Technology on Home Dialysis.","authors":"Susie Q Lew, Sabrina Milan Manani, Claudio Ronco, Mitchell H Rosner, James A Sloand","doi":"10.2215/CJN.0000000000000405","DOIUrl":"10.2215/CJN.0000000000000405","url":null,"abstract":"<p><p>In the United States, regulatory changes dictate telehealth activities. Telehealth was available to patients on home dialysis as early as 2019, allowing patients to opt for telehealth with home as the originating site and without geographic restriction. In 2020, coronavirus disease 2019 was an unexpected accelerant for telehealth use in the United States. Within nephrology, remote patient monitoring has most often been applied to the care of patients on home dialysis modalities. The effect that remote and virtual technologies have on home dialysis patients, telehealth and health care disparities, and health care providers' workflow changes are discussed here. Moreover, the future use of remote and virtual technologies to include artificial intelligence and artificial neural network model to optimize and personalize treatments will be highlighted. Despite these advances in technology challenges continue to exist, leaving room for future innovation to improve patient health outcome and equity. Prospective studies are needed to further understand the effect of using virtual technologies and remote monitoring on home dialysis outcomes, cost, and patient engagement.</p>","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":null,"pages":null},"PeriodicalIF":8.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11469790/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139378728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antihypertensive Drug Treatment and the Risk for Intrahemodialysis Hypotension.","authors":"Carmine Zoccali, Giovanni Tripepi, Paola Carioni, Edouard L Fu, Friedo Dekker, Vianda Stel, Kitty J Jager, Francesca Mallamaci, Jeffrey L Hymes, Franklin W Maddux, Stefano Stuard","doi":"10.2215/CJN.0000000000000521","DOIUrl":"10.2215/CJN.0000000000000521","url":null,"abstract":"","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":null,"pages":null},"PeriodicalIF":8.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11469783/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141629237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between Chronic Kidney Disease-Mineral and Bone Disorder Biomarkers and Symptom Burden in Older Patients with Advanced Chronic Kidney Disease: Results from the EQUAL Study.","authors":"Lorenza Magagnoli, Mario Cozzolino, Marie Evans, Fergus J Caskey, Friedo W Dekker, Claudia Torino, Maciej Szymczak, Christiane Drechsler, Maria Pippias, Antonio Vilasi, Roemer J Janse, Magdalena Krajewska, Vianda S Stel, Kitty J Jager, Nicholas C Chesnaye","doi":"10.2215/CJN.0000000000000510","DOIUrl":"10.2215/CJN.0000000000000510","url":null,"abstract":"","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":null,"pages":null},"PeriodicalIF":8.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11469787/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141749571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intradialytic Hypotension in the Face of Using Different Antihypertensive Medication Classes.","authors":"Csaba P Kovesdy","doi":"10.2215/CJN.0000000000000572","DOIUrl":"10.2215/CJN.0000000000000572","url":null,"abstract":"","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":null,"pages":null},"PeriodicalIF":8.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11469771/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142127233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diurnal and Daily Symptom Variation in Patients with ESKD.","authors":"Dawn P Edwards","doi":"10.2215/CJN.0000000000000573","DOIUrl":"https://doi.org/10.2215/CJN.0000000000000573","url":null,"abstract":"","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":null,"pages":null},"PeriodicalIF":8.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11469763/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142512350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Infection-Related GN with Cutaneous Vasculitis.","authors":"Jodi Gedallovich, Ralph M Mohty, Ksenia Kasimova, Zhengchun Lu, Vivek Charu, John P Higgins, Neeraja Kambham, Vanderlene L Kung, Megan L Troxell","doi":"10.2215/CJN.0000000000000503","DOIUrl":"10.2215/CJN.0000000000000503","url":null,"abstract":"","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":null,"pages":null},"PeriodicalIF":8.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11469774/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141460585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Large Discordance between Creatinine-Based and Cystatin C-Based eGFRs is Associated with Falls, Hospitalizations, and Death in Older Adults.","authors":"Nurit Katz-Agranov, Meghan L Rieu-Werden, Ayush Thacker, Jacquelyn M Lykken, Meghan E Sise, Sachin J Shah","doi":"10.2215/CJN.0000000000000523","DOIUrl":"10.2215/CJN.0000000000000523","url":null,"abstract":"","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":null,"pages":null},"PeriodicalIF":8.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11469786/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141989436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Role of Repeat Kidney Biopsies in Lupus Nephritis in a Largely Black and Hispanic Population.","authors":"Anitha Ramu, Rosalba Santana de Roberts, Nang San Hti Lar Seng, Gopisree Peringeth, Hana Rajevac, James M Pullman, Meryl Waldman, Ladan Golestaneh, Belinda Jim","doi":"10.2215/CJN.0000000000000556","DOIUrl":"https://doi.org/10.2215/CJN.0000000000000556","url":null,"abstract":"","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":null,"pages":null},"PeriodicalIF":8.5,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142331748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Living donation and pregnancy complications: State of the evidence and ‘call-to-action’ for improved risk assessment","authors":"Ana P. Rossi, Goni Katz-Greenberg, Lisa Coscia, Carla W. Brady, Christina Doligalski, Roxanna A. Irani, Arthur Matas, Silvi Shah, Krista L. Lentine, Contraception and Pregnancy after Transplantation and Living Donation Controversies Conference Participants on behalf of the AST WHCOP Reproductive Health","doi":"10.2215/cjn.0000000593","DOIUrl":"https://doi.org/10.2215/cjn.0000000593","url":null,"abstract":"of donation on future pregnancies as well as the impact of pregnancy complications on postdonation outcomes. In February of 2023, the American Society of Transplantation Women’s Health Community of Practice held a virtual Controversies Conference on reproductive health, contraception and pregnancy after transplantation and living donation. Experts in the field presented the available data. Smaller breakout sessions were created to discuss findings, identify knowledge gaps and develop recommendations. Herein we present the conference findings related to living donation. The evidence reviewed shows that gestational hypertension and gestational diabetes mellitus pre-kidney donation have been associated with an increased risk of developing postdonation hypertension and diabetes mellitus respectively, without increasing the risk of developing an estimated glomerular filtration rate &lt;45 ml/min postdonation. The risk of preeclampsia in living kidney donors increases to 4-10% and low dose aspirin may help reduce that risk. Little is known about the financial burden of living donors that become pregnant, their risk of postpartum depression or the optimal time between donation and conception. The data on living liver donors is even scarcer. The creation of a registry of donor candidates may help answer many of these questions and in turn educate prospective donors so they can make an informed choice. Living kidney and liver donation significantly increase the organ supply to make lifesaving transplant possible, offering a survival advantage to the recipient and cost savings to the society. Of all living donors 40% are women of childbearing age. However limited data exist regarding the impact of donation on future pregnancies as well as the impact of pregnancy complications on postdonation outcomes. In February of 2023, the American Society of Transplantation Women’s Health Community of Practice held a virtual Controversies Conference on reproductive health, contraception and pregnancy after transplantation and living donation. Experts in the field presented the available data. Smaller breakout sessions were created to discuss findings, identify knowledge gaps and develop recommendations. Herein we present the conference findings related to living donation. The evidence reviewed shows that gestational hypertension and gestational diabetes mellitus pre-kidney donation have been associated with an increased risk of developing postdonation hypertension and diabetes mellitus respectively, without increasing the risk of developing an estimated glomerular filtration rate &lt;45 ml/min postdonation. The risk of preeclampsia in living kidney donors increases to 4-10% and low dose aspirin may help reduce that risk. Little is known about the financial burden of living donors that become pregnant, their risk of postpartum depression or the optimal time between donation and conception. The data on living liver donors is even scarcer. The creation of a registry of donor ca","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":null,"pages":null},"PeriodicalIF":9.8,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142321554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Medication Burden and Adverse Cardiovascular Events and Death in Patients Treated with Maintenance Hemodialysis: A Nationwide Cohort Study","authors":"Cheol Ho Park, Ye Eun Ko, Ga Young Heo, Bo Yeon Kim, Seong Ju Oh, So Young Han, Jung Tak Park, Seung Hyeok Han, Tae-Hyun Yoo, Shin-Wook Kang, Hyung Woo Kim","doi":"10.2215/cjn.0000000000000570","DOIUrl":"https://doi.org/10.2215/cjn.0000000000000570","url":null,"abstract":"ied to investigate the prognostic implications of medication burden regarding adverse outcomes in patients with end-stage kidney disease with maintenance hemodialysis. Methods We analyzed 26,690 patients receiving maintenance hemodialysis who participated in the Periodic Hemodialysis Quality Assessment conducted by the Health Insurance Review and Assessment Service. The exposure of interest was the number of routinely prescribed oral medications. The main outcome was a composite of non-fatal cardiovascular events (non-fatal myocardial infarction, coronary revascularization, non-fatal stroke, or hospitalization for heart failure) or all-cause death (major adverse cardiac and cerebrovascular events). The secondary outcomes were the individual components of the primary outcome. Results During a follow-up period of 146,749 person-years (median, 6.0 years), major adverse cardiac and cerebrovascular events occurred in 17,573 (59.2%) patients. Higher medication burden was associated with progressively higher incidence of major adverse cardiac and cerebrovascular events (84.7, 107.2, 130.2, and 168.9 events per 1000 person-years in Q1–Q4, respectively). In a multivariable Cox proportional hazard model, the adjusted hazard ratios (95% confidence intervals) for the second, third, and highest quartiles were 1.05 (1.00–1.10), 1.12 (1.07–1.17), and 1.27 (1.21–1.33), respectively, compared with the lowest quartile. In continuous modeling, each increase in the number of medication was associated with a 1.03-fold (95% confidence interval 1.03–1.04) higher risk of the primary outcome. Conclusion A high medication burden was independently associated with higher risk of adverse cardiovascular outcomes and all-cause death in patients receiving maintenance hemodialysis. These findings suggest that a high medication burden could be a useful indicator of adverse clinical outcomes in patients undergoing hemodialysis. Copyright © 2024 by the American Society of Nephrology...","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":null,"pages":null},"PeriodicalIF":9.8,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142321555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}