Pub Date : 2024-11-01Epub Date: 2024-08-06DOI: 10.2215/CJN.0000000000000511
Qandeel H Soomro, Shuojohn Li, Angela McCarthy, Dalila Varela, Javaughn Ways, Amalya M Charytan, Colin Keane, Giana Ramos, Joey Nicholson, David M Charytan
{"title":"Gender Differences in Citation Rate: An Analysis of Randomized Controlled Trials in Nephrology High-Impact Journals Over Two Decades.","authors":"Qandeel H Soomro, Shuojohn Li, Angela McCarthy, Dalila Varela, Javaughn Ways, Amalya M Charytan, Colin Keane, Giana Ramos, Joey Nicholson, David M Charytan","doi":"10.2215/CJN.0000000000000511","DOIUrl":"10.2215/CJN.0000000000000511","url":null,"abstract":"","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":" ","pages":"1453-1460"},"PeriodicalIF":8.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11556916/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141903486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-01Epub Date: 2024-08-14DOI: 10.2215/CJN.0000000000000538
Dillon Winkelman, Julie Smith-Gagen, Casey M Rebholz, Orlando M Gutierrez, David E St-Jules
{"title":"Association of Intake of Whole Grains with Health Outcomes in the Chronic Renal Insufficiency Cohort Study.","authors":"Dillon Winkelman, Julie Smith-Gagen, Casey M Rebholz, Orlando M Gutierrez, David E St-Jules","doi":"10.2215/CJN.0000000000000538","DOIUrl":"10.2215/CJN.0000000000000538","url":null,"abstract":"","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":" ","pages":"1435-1443"},"PeriodicalIF":8.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11556944/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141983813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Whole Grains, Refined Grains, and Diet Quality in Chronic Kidney Disease.","authors":"Susanne Fleig, Martin K Kuhlmann","doi":"10.2215/CJN.0000000595","DOIUrl":"10.2215/CJN.0000000595","url":null,"abstract":"","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":"19 11","pages":"1365-1367"},"PeriodicalIF":8.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11556909/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142606178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-01Epub Date: 2024-08-21DOI: 10.2215/CJN.0000000000000531
Sarah M Haeger, Kayo Okamura, Amy S Li, Zhibin He, Bryan D Park, Isadore M Budnick, North Foulon, Matthew Kennis, Rachel E Blaine, Makoto Miyazaki, Ruth Campbell, Diana I Jalal, James F Colbert, John T Brinton, Benjamin R Griffin, Sarah Faubel
{"title":"Cystatin C and Kidney Function Recovery in Patients Requiring Continuous KRT for Acute Kidney Injury.","authors":"Sarah M Haeger, Kayo Okamura, Amy S Li, Zhibin He, Bryan D Park, Isadore M Budnick, North Foulon, Matthew Kennis, Rachel E Blaine, Makoto Miyazaki, Ruth Campbell, Diana I Jalal, James F Colbert, John T Brinton, Benjamin R Griffin, Sarah Faubel","doi":"10.2215/CJN.0000000000000531","DOIUrl":"10.2215/CJN.0000000000000531","url":null,"abstract":"","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":" ","pages":"1395-1404"},"PeriodicalIF":8.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11556902/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142019464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-01Epub Date: 2024-08-26DOI: 10.2215/CJN.0000000000000565
Jasmine Berry, Aubriana Perez, Mengyu Di, Chengcheng Hu, Stephen O Pastan, Rachel E Patzer, Jessica L Harding
{"title":"The Association between Residential Segregation and Access to Kidney Transplantation: Evidence from a Multistate Cohort Study.","authors":"Jasmine Berry, Aubriana Perez, Mengyu Di, Chengcheng Hu, Stephen O Pastan, Rachel E Patzer, Jessica L Harding","doi":"10.2215/CJN.0000000000000565","DOIUrl":"10.2215/CJN.0000000000000565","url":null,"abstract":"","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":" ","pages":"1473-1484"},"PeriodicalIF":8.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11556903/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142074482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-01Epub Date: 2024-10-04DOI: 10.2215/CJN.0000000585
Liz Lightstone
{"title":"Gender Equity in Academic Nephrology: Enough Talk, Now Is the Time to Act.","authors":"Liz Lightstone","doi":"10.2215/CJN.0000000585","DOIUrl":"10.2215/CJN.0000000585","url":null,"abstract":"","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":" ","pages":"1368-1370"},"PeriodicalIF":8.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11556935/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142373467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-01Epub Date: 2024-01-08DOI: 10.2215/CJN.0000000000000424
Matthew B Rivara, Jonathan Himmelfarb
Although the past two decades have seen substantial proportional growth of home hemodialysis in the United States, the absolute number of patients treated with home hemodialysis remains small. Currently available stationary hemodialysis devices for use in the home have inherent limitations that represent barriers for more widespread adoption by a larger proportion of individuals with kidney failure. These limitations include device weight and bulk, ergonomics considerations, technical complexity, vascular access challenges, and limited remote patient monitoring. Recent years have witnessed a resurgence in research and development of prototype wearable kidney replacement devices incorporating innovations in miniaturization, new biomaterials, and new methods for toxin clearance and dialysate regeneration. Recent work has built on five decades of incremental innovation in wearable dialysis concepts and prototypes, starting from the work by Kolff in the 1970s. Wearable dialysis devices that successfully overcome key persistent barriers to successful development and adoption of these technologies will radically reshape the landscape of kidney replacement therapies and have the potential to dramatically improve the lives of individuals living with kidney failure.
{"title":"From Home to Wearable Hemodialysis: Barriers, Progress, and Opportunities.","authors":"Matthew B Rivara, Jonathan Himmelfarb","doi":"10.2215/CJN.0000000000000424","DOIUrl":"10.2215/CJN.0000000000000424","url":null,"abstract":"<p><p>Although the past two decades have seen substantial proportional growth of home hemodialysis in the United States, the absolute number of patients treated with home hemodialysis remains small. Currently available stationary hemodialysis devices for use in the home have inherent limitations that represent barriers for more widespread adoption by a larger proportion of individuals with kidney failure. These limitations include device weight and bulk, ergonomics considerations, technical complexity, vascular access challenges, and limited remote patient monitoring. Recent years have witnessed a resurgence in research and development of prototype wearable kidney replacement devices incorporating innovations in miniaturization, new biomaterials, and new methods for toxin clearance and dialysate regeneration. Recent work has built on five decades of incremental innovation in wearable dialysis concepts and prototypes, starting from the work by Kolff in the 1970s. Wearable dialysis devices that successfully overcome key persistent barriers to successful development and adoption of these technologies will radically reshape the landscape of kidney replacement therapies and have the potential to dramatically improve the lives of individuals living with kidney failure.</p>","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":" ","pages":"1488-1495"},"PeriodicalIF":8.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11556920/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139378727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Exercise and Cognition in People with Chronic Kidney Disease.","authors":"Nicole Scholes-Robertson","doi":"10.2215/CJN.0000000589","DOIUrl":"10.2215/CJN.0000000589","url":null,"abstract":"","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":"19 11","pages":"1357-1358"},"PeriodicalIF":8.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11556926/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142605221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-01Epub Date: 2024-07-22DOI: 10.2215/CJN.0000000000000540
Teena Zachariah, Jai Radhakrishnan
Glomerular disease is a leading cause of CKD and ESKD. Although diabetic kidney disease is the most common cause of glomerular disease, nondiabetic causes include malignancy, systemic autoimmune conditions, drug effects, or genetic conditions. Nondiabetic glomerular diseases are rare diseases, with a paucity of high-quality clinical trials in this area. Furthermore, late referral can result in poor patient outcomes. This article reviews the current management of nondiabetic glomerular disease and explores the latest developments in drug treatment in this area. Current treatment of nondiabetic glomerular disease aims to manage complications (edema, hypertension, proteinuria, hyperlipidemia, hypercoagulability, and thrombosis) as well as target the underlying cause of glomerular disease. Treatment options include renin-angiotensin-aldosterone system inhibitors, statins/nonstatin alternatives, loop diuretics, anticoagulation agents, immunosuppressives, and lifestyle and dietary modifications. Effective treatment of nondiabetic glomerular disease is limited by heterogeneity and a lack of understanding of the disease pathogenesis. Sodium-glucose cotransporter-2 inhibitors and nonsteroidal mineralocorticoid receptor antagonists (ns-MRAs, such as finerenone), with their broad anti-inflammatory and antifibrotic effects, have emerged as valuable therapeutic options for a range of cardiorenal conditions, including CKD. ns-MRAs are an evolving drug class of particular interest for the future treatment of nondiabetic glomerular disease, and there is evidence that these agents may improve kidney prognosis in various subgroups of patients with CKD. The benefits offered by ns-MRAs may present an opportunity to reduce the progression of CKD from a spectrum of glomerular disease. Several novel ns-MRA are in clinical development for both diabetic and nondiabetic CKD.
{"title":"Potential Role of Mineralocorticoid Receptor Antagonists in Nondiabetic Chronic Kidney Disease and Glomerular Disease.","authors":"Teena Zachariah, Jai Radhakrishnan","doi":"10.2215/CJN.0000000000000540","DOIUrl":"10.2215/CJN.0000000000000540","url":null,"abstract":"<p><p>Glomerular disease is a leading cause of CKD and ESKD. Although diabetic kidney disease is the most common cause of glomerular disease, nondiabetic causes include malignancy, systemic autoimmune conditions, drug effects, or genetic conditions. Nondiabetic glomerular diseases are rare diseases, with a paucity of high-quality clinical trials in this area. Furthermore, late referral can result in poor patient outcomes. This article reviews the current management of nondiabetic glomerular disease and explores the latest developments in drug treatment in this area. Current treatment of nondiabetic glomerular disease aims to manage complications (edema, hypertension, proteinuria, hyperlipidemia, hypercoagulability, and thrombosis) as well as target the underlying cause of glomerular disease. Treatment options include renin-angiotensin-aldosterone system inhibitors, statins/nonstatin alternatives, loop diuretics, anticoagulation agents, immunosuppressives, and lifestyle and dietary modifications. Effective treatment of nondiabetic glomerular disease is limited by heterogeneity and a lack of understanding of the disease pathogenesis. Sodium-glucose cotransporter-2 inhibitors and nonsteroidal mineralocorticoid receptor antagonists (ns-MRAs, such as finerenone), with their broad anti-inflammatory and antifibrotic effects, have emerged as valuable therapeutic options for a range of cardiorenal conditions, including CKD. ns-MRAs are an evolving drug class of particular interest for the future treatment of nondiabetic glomerular disease, and there is evidence that these agents may improve kidney prognosis in various subgroups of patients with CKD. The benefits offered by ns-MRAs may present an opportunity to reduce the progression of CKD from a spectrum of glomerular disease. Several novel ns-MRA are in clinical development for both diabetic and nondiabetic CKD.</p>","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":" ","pages":"1499-1512"},"PeriodicalIF":8.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11556932/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141749572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-01Epub Date: 2024-07-31DOI: 10.2215/CJN.0000000000000533
Ellen Bradshaw, Abdulfattah Alejmi, Gabriella Rossetti, Giovanni D'Avossa, Jamie Hugo Macdonald
{"title":"Exercise and Cognitive Function in Chronic Kidney Disease: A Systematic Review and Meta-Analysis of Efficacy and Harms.","authors":"Ellen Bradshaw, Abdulfattah Alejmi, Gabriella Rossetti, Giovanni D'Avossa, Jamie Hugo Macdonald","doi":"10.2215/CJN.0000000000000533","DOIUrl":"10.2215/CJN.0000000000000533","url":null,"abstract":"","PeriodicalId":50681,"journal":{"name":"Clinical Journal of the American Society of Nephrology","volume":" ","pages":"1461-1472"},"PeriodicalIF":8.5,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11556908/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141861460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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