Pub Date : 2022-04-01Epub Date: 2021-08-18DOI: 10.1007/s00104-021-01482-x
A Winter, M M Maurer, M Schmelzle, T Malinka, M Biebl, P Fikatas, D Kröll, I M Sauer, M Hippler-Benscheidt, J Pratschke, S Chopra
Against the background of the growing economization of clinical medicine, in the last decades the topics of risk and complication management have also become more important in surgical disciplines. The standardization and reproducible documentation of outcome and complication data play a key role for valid quality control. In this article a digital system implemented at the surgical clinic of the Charité University Medicine in Berlin is analyzed with respect to its practicability for perioperative and postoperative monitoring of complications within the framework of quality assurance.
{"title":"[Digital documentation of complications in visceral surgery: possibilities and evaluation of an instrument for quality management].","authors":"A Winter, M M Maurer, M Schmelzle, T Malinka, M Biebl, P Fikatas, D Kröll, I M Sauer, M Hippler-Benscheidt, J Pratschke, S Chopra","doi":"10.1007/s00104-021-01482-x","DOIUrl":"https://doi.org/10.1007/s00104-021-01482-x","url":null,"abstract":"<p><p>Against the background of the growing economization of clinical medicine, in the last decades the topics of risk and complication management have also become more important in surgical disciplines. The standardization and reproducible documentation of outcome and complication data play a key role for valid quality control. In this article a digital system implemented at the surgical clinic of the Charité University Medicine in Berlin is analyzed with respect to its practicability for perioperative and postoperative monitoring of complications within the framework of quality assurance.</p>","PeriodicalId":50700,"journal":{"name":"Chirurg","volume":"93 4","pages":"381-387"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s00104-021-01482-x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39321905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-04-01Epub Date: 2022-02-23DOI: 10.1007/s00104-022-01596-w
Hauke Lang, Peter Philipp Grimminger, Hans-Joachim Meyer
The scientifically founded surgical specialist discussion regarding the legal requirements for minimum volume numbers for diverse organ systems and selected surgical procedures as the basis of quality assurance and optimization of treatment is not new. Comprehensive and also reliable data from national and international studies are available for colorectal surgery, pancreatic surgery, esophageal surgery, liver surgery and gastric surgery. Recently, the raising of the minimum volume for complex esophageal interventions by the Federal Joint Committee (G-BA) in Germany from 10 up to 26 procedures per hospital and year, reignited the debate on this topic as well as the debate on centralization in the healthcare system in general. This decision seems to be scientifically well-justified from the perspective of political bodies and realizable in the practical implementation; however, from the perspective of physicians routinely involved in the corresponding highly complex procedures, there is a very much broader basis for discussion, which is only partially covered by a report of the Institute for Quality and Efficiency in the Healthcare System (IQWiG) as the foundation of the decision of the G‑BA. For the scientifically oriented surgical specialist society, in the first instance priority is given to the scientific evidence as the guiding principle. Nevertheless, aspects of the treatment reality cannot and should not be ignored. Therefore, the recommendations of the specialist society must be oriented not only to the quality of results but also to the realistic options for successful implementation in practice. Furthermore, questions of further education, the right of the patient to freedom of choice of the physician and preservation of the attractiveness of the occupational profile of surgeons are immanent topics for the surgical specialist society.
{"title":"[Minimum case volume regulations in surgery from the perspective of the specialist society (DGCH) : Balancing act between science, politics, treatment reality and a range of other aspects].","authors":"Hauke Lang, Peter Philipp Grimminger, Hans-Joachim Meyer","doi":"10.1007/s00104-022-01596-w","DOIUrl":"https://doi.org/10.1007/s00104-022-01596-w","url":null,"abstract":"<p><p>The scientifically founded surgical specialist discussion regarding the legal requirements for minimum volume numbers for diverse organ systems and selected surgical procedures as the basis of quality assurance and optimization of treatment is not new. Comprehensive and also reliable data from national and international studies are available for colorectal surgery, pancreatic surgery, esophageal surgery, liver surgery and gastric surgery. Recently, the raising of the minimum volume for complex esophageal interventions by the Federal Joint Committee (G-BA) in Germany from 10 up to 26 procedures per hospital and year, reignited the debate on this topic as well as the debate on centralization in the healthcare system in general. This decision seems to be scientifically well-justified from the perspective of political bodies and realizable in the practical implementation; however, from the perspective of physicians routinely involved in the corresponding highly complex procedures, there is a very much broader basis for discussion, which is only partially covered by a report of the Institute for Quality and Efficiency in the Healthcare System (IQWiG) as the foundation of the decision of the G‑BA. For the scientifically oriented surgical specialist society, in the first instance priority is given to the scientific evidence as the guiding principle. Nevertheless, aspects of the treatment reality cannot and should not be ignored. Therefore, the recommendations of the specialist society must be oriented not only to the quality of results but also to the realistic options for successful implementation in practice. Furthermore, questions of further education, the right of the patient to freedom of choice of the physician and preservation of the attractiveness of the occupational profile of surgeons are immanent topics for the surgical specialist society.</p>","PeriodicalId":50700,"journal":{"name":"Chirurg","volume":"93 4","pages":"342-348"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8864976/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39808450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-04-01Epub Date: 2022-03-22DOI: 10.1007/s00104-022-01587-x
Horst Schuster, Peter Follert
The minimum case volume regulations of the Federal Joint Committee determine the size of the respective annual minimum number for each site of a hospital, for selected scheduled inpatient services where the quality of the treatment results is dependent on the number of services carried out. In addition, further details on the elucidation of the prognosis are determined in the regulations. Due to the legally defined prognostic procedure as a prerequisite for a prospective justification for service provision, new or altered minimum case volumes come into effect even before the end of the validity period established on the justification for provision of services. The Federal Joint Committee established this basic principle also for the introduction procedure in a resolution from 16 December 2021. This article explains the background and should support the implementation.
{"title":"[Minimum case volume regulations of the Federal Joint Committee : Mode of function and application in practice].","authors":"Horst Schuster, Peter Follert","doi":"10.1007/s00104-022-01587-x","DOIUrl":"https://doi.org/10.1007/s00104-022-01587-x","url":null,"abstract":"<p><p>The minimum case volume regulations of the Federal Joint Committee determine the size of the respective annual minimum number for each site of a hospital, for selected scheduled inpatient services where the quality of the treatment results is dependent on the number of services carried out. In addition, further details on the elucidation of the prognosis are determined in the regulations. Due to the legally defined prognostic procedure as a prerequisite for a prospective justification for service provision, new or altered minimum case volumes come into effect even before the end of the validity period established on the justification for provision of services. The Federal Joint Committee established this basic principle also for the introduction procedure in a resolution from 16 December 2021. This article explains the background and should support the implementation.</p>","PeriodicalId":50700,"journal":{"name":"Chirurg","volume":" ","pages":"325-334"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40313958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-28DOI: 10.1007/s00104-022-01633-8
J. Betzler, P. Piso, R. Hofheinz, C. Reissfelder
{"title":"Multizentrische, randomisiert-kontrollierte Studien der ACO/AIO/ARO","authors":"J. Betzler, P. Piso, R. Hofheinz, C. Reissfelder","doi":"10.1007/s00104-022-01633-8","DOIUrl":"https://doi.org/10.1007/s00104-022-01633-8","url":null,"abstract":"","PeriodicalId":50700,"journal":{"name":"Chirurg","volume":"93 1","pages":"409-412"},"PeriodicalIF":0.0,"publicationDate":"2022-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43764871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-28DOI: 10.1007/s00104-022-01599-7
R. Siegel, F. Aigner
{"title":"Webinar zur S3-Leitlinie „Diagnostik, Therapie und Nachsorge von Analkanal- und Analrandkarzinomen“","authors":"R. Siegel, F. Aigner","doi":"10.1007/s00104-022-01599-7","DOIUrl":"https://doi.org/10.1007/s00104-022-01599-7","url":null,"abstract":"","PeriodicalId":50700,"journal":{"name":"Chirurg","volume":"93 1","pages":"413-414"},"PeriodicalIF":0.0,"publicationDate":"2022-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42657236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-01Epub Date: 2022-02-22DOI: 10.1007/s00104-022-01610-1
R Keiner, M Ardelt, U Settmacher
{"title":"[Targeted intraoperative molecular imaging for localization of nonpalpable tumors and quantification of resection margin distances].","authors":"R Keiner, M Ardelt, U Settmacher","doi":"10.1007/s00104-022-01610-1","DOIUrl":"https://doi.org/10.1007/s00104-022-01610-1","url":null,"abstract":"","PeriodicalId":50700,"journal":{"name":"Chirurg","volume":"93 3","pages":"307-308"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39943205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-01Epub Date: 2021-07-23DOI: 10.1007/s00104-021-01470-1
J Sterz, V Britz, P Carstensen, T Kollewe, S H Voß, M C Stefanescu, T Schreckenbach, R D Verboket, Miriam Rüsseler
Background: Thus medical students must be inspired to undertake this specialty. Students complain that the teaching is subordinate to patient care and limited by a lack of time and medical personnel. Although there are many studies assessing student perceptions, few exist that focus on the issues that teachers face.
Objective: To analyse student teaching in the daily routine and its potential' problems from the surgeon's perspectives.
Material and methods: In this prospective study guidelines for semistructured interviews with formulated, open questions were created, which were specified with further questions. All interviews were conducted using these guidelines and recorded. The number of interviews were a function of the concept of content saturation.
Results: All 22 participants perceived that the teaching in clinical practice is of paramount importance. Nevertheless, respondents described that learning goals in the clinical routine are not always achieved. The main reason is a lack of time; however, as clinical experience increases other factors will similarly become more important: Consultants and heads of departments complain about deficiencies in students' previous knowledge, including insufficient motivation. Most respondents described that they do not feel appreciated for teaching. Overall, student teaching was perceived as an additional burden but all respondents found the task to be extremely worthwhile.
Conclusion: In addition to the lack of personnel, a lack of appreciation is the most significant obstacle towards effective teaching. It is therefore important to increase the value of teaching by rewarding good achievements and the creation of effective transparency.
{"title":"[The surgeon's balancing act-Teaching in the clinical routine].","authors":"J Sterz, V Britz, P Carstensen, T Kollewe, S H Voß, M C Stefanescu, T Schreckenbach, R D Verboket, Miriam Rüsseler","doi":"10.1007/s00104-021-01470-1","DOIUrl":"10.1007/s00104-021-01470-1","url":null,"abstract":"<p><strong>Background: </strong>Thus medical students must be inspired to undertake this specialty. Students complain that the teaching is subordinate to patient care and limited by a lack of time and medical personnel. Although there are many studies assessing student perceptions, few exist that focus on the issues that teachers face.</p><p><strong>Objective: </strong>To analyse student teaching in the daily routine and its potential' problems from the surgeon's perspectives.</p><p><strong>Material and methods: </strong>In this prospective study guidelines for semistructured interviews with formulated, open questions were created, which were specified with further questions. All interviews were conducted using these guidelines and recorded. The number of interviews were a function of the concept of content saturation.</p><p><strong>Results: </strong>All 22 participants perceived that the teaching in clinical practice is of paramount importance. Nevertheless, respondents described that learning goals in the clinical routine are not always achieved. The main reason is a lack of time; however, as clinical experience increases other factors will similarly become more important: Consultants and heads of departments complain about deficiencies in students' previous knowledge, including insufficient motivation. Most respondents described that they do not feel appreciated for teaching. Overall, student teaching was perceived as an additional burden but all respondents found the task to be extremely worthwhile.</p><p><strong>Conclusion: </strong>In addition to the lack of personnel, a lack of appreciation is the most significant obstacle towards effective teaching. It is therefore important to increase the value of teaching by rewarding good achievements and the creation of effective transparency.</p>","PeriodicalId":50700,"journal":{"name":"Chirurg","volume":"93 3","pages":"286-291"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894151/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39212337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-01Epub Date: 2022-01-27DOI: 10.1007/s00104-022-01593-z
Khosro Hekmat, Christiane J Bruns
{"title":"[ASCO guideline for the management of stage III NSCLC Part 2: Indications for surgery].","authors":"Khosro Hekmat, Christiane J Bruns","doi":"10.1007/s00104-022-01593-z","DOIUrl":"https://doi.org/10.1007/s00104-022-01593-z","url":null,"abstract":"","PeriodicalId":50700,"journal":{"name":"Chirurg","volume":"93 3","pages":"309"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39964413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-01Epub Date: 2021-12-14DOI: 10.1007/s00104-021-01552-0
Henning Niebuhr, Zaid Omar Malaibari, Ferdinand Köckerling, Wolfgang Reinpold, Halil Dag, Dietmar Eucker, Thomas Aufenberg, Panagiotis Fikatas, René H Fortelny, Jan Kukleta, Hansjörg Meier, Christian Flamm, Guido Baschleben, Marius Helmedag
Objective: The aim was to evaluate the effectiveness, clinical practicability, and complication rate of the intraoperative fascial traction (IFT) procedure for the treatment of large ventral hernias.
Method: This study evaluated 50 patients from 11 specialized centers with an intraoperatively measured fascial distance of more than 8 cm, who were treated by IFT (traction time 30-35 min) using the fasciotens® hernia traction procedure.
Results: Fascial gaps measured preoperatively ranged from 8 cm to 44 cm, with most patients (94%) having a fascial gap above 10 cm (W3 according to the European Hernia Society classification). The mean fascial distance was reduced from 16.1 ± 0.8 cm to 5.8 ± 0.7 cm (stretch gain 10.2 ± 0.7 cm, p < 0.0001, Wilcoxon matched-pairs signed-ranks test). A reduction in fascial distance of at least 50% was achieved in three quarters of the patients and in half of the treated patients the reduction in fascial distance amounted to even more than 70%. The closure rate achieved by IFT after a mean surgical duration of 207.3 ± 11.0 min was 90% (45/50). Hernia closure was performed in all cases with a mesh augmentation in a sublay position. Postoperative complications occurred in 6 patients (12%). A reoperation was required in 3 patients (6%).
Conclusion: The described IFT method is a new procedure for abdominal wall closure in large ventral hernias. The presented results demonstrate a high effectiveness, a good clinical practicability and a low complication rate of IFT.
目的:评价术中筋膜牵引(IFT)术治疗腹大疝的疗效、临床实用性及并发症发生率。方法:本研究评估了来自11个专科中心的50例患者,术中测量的筋膜距离大于8 cm,采用筋膜筋膜®疝牵引方法进行IFT治疗(牵引时间30-35 min)。结果:术前测量的筋膜间隙范围为8 cm至44 cm,大多数患者(94%)的筋膜间隙大于10 cm(根据欧洲疝学会分类W3)。平均筋膜距离由16.1 ±0.8 cm缩短至5.8 ±0.7 cm(拉伸增加10.2 ±0.7 cm, p )。结论:所述的IFT方法是大腹疝腹壁闭合的一种新方法。结果表明,体外移植术疗效高,临床实用性好,并发症发生率低。
{"title":"[Intraoperative fascial traction (IFT) for treatment of large ventral hernias : A retrospective analysis of 50 cases].","authors":"Henning Niebuhr, Zaid Omar Malaibari, Ferdinand Köckerling, Wolfgang Reinpold, Halil Dag, Dietmar Eucker, Thomas Aufenberg, Panagiotis Fikatas, René H Fortelny, Jan Kukleta, Hansjörg Meier, Christian Flamm, Guido Baschleben, Marius Helmedag","doi":"10.1007/s00104-021-01552-0","DOIUrl":"https://doi.org/10.1007/s00104-021-01552-0","url":null,"abstract":"<p><strong>Objective: </strong>The aim was to evaluate the effectiveness, clinical practicability, and complication rate of the intraoperative fascial traction (IFT) procedure for the treatment of large ventral hernias.</p><p><strong>Method: </strong>This study evaluated 50 patients from 11 specialized centers with an intraoperatively measured fascial distance of more than 8 cm, who were treated by IFT (traction time 30-35 min) using the fasciotens® hernia traction procedure.</p><p><strong>Results: </strong>Fascial gaps measured preoperatively ranged from 8 cm to 44 cm, with most patients (94%) having a fascial gap above 10 cm (W3 according to the European Hernia Society classification). The mean fascial distance was reduced from 16.1 ± 0.8 cm to 5.8 ± 0.7 cm (stretch gain 10.2 ± 0.7 cm, p < 0.0001, Wilcoxon matched-pairs signed-ranks test). A reduction in fascial distance of at least 50% was achieved in three quarters of the patients and in half of the treated patients the reduction in fascial distance amounted to even more than 70%. The closure rate achieved by IFT after a mean surgical duration of 207.3 ± 11.0 min was 90% (45/50). Hernia closure was performed in all cases with a mesh augmentation in a sublay position. Postoperative complications occurred in 6 patients (12%). A reoperation was required in 3 patients (6%).</p><p><strong>Conclusion: </strong>The described IFT method is a new procedure for abdominal wall closure in large ventral hernias. The presented results demonstrate a high effectiveness, a good clinical practicability and a low complication rate of IFT.</p>","PeriodicalId":50700,"journal":{"name":"Chirurg","volume":"93 3","pages":"292-298"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894171/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39838035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-01Epub Date: 2021-10-19DOI: 10.1007/s00104-021-01521-7
Romana Lenzen-Großimlinghaus
Geriatric patients often have cardiovascular diseases that require differentiated perioperative management of hemostasis. The operation-related bleeding risk and the individual thromboembolism risk mutually influence each other, so that a differentiated preoperative assessment of the further prescription of coagulation-modulating medication is required. In many cases the active coagulation medication can be interrupted without replacement or continued unchanged. In cardiovascular diseases with antiplatelet medication, the preoperative risk-benefit assessment for most operations leads to the continuation of previous platelet aggregation inhibitor monotherapy; however, if there is a high risk of cardiovascular thromboembolism with dual platelet inhibition, the individual perioperative medication should be closely coordinated with a geriatrician or cardiologist.In most cases, the intake of vitamin K antagonists (VKA) can be preoperatively interrupted. In cases of high risk of thromboembolism, a temporary bridging with heparin must be carried out. The introduction of the four new direct oral antagonists (DOAC) has made the perioperative management of anticoagulation much easier. Bridging with heparin is not necessary. Perioperatively, only the dosage and timing of interruption of the DOACs have to be determined individually depending on the operative bleeding risk as well as the age, body weight and kidney function of the patient. If bleeding complications arise under the influence of the DOACs, antidotes are available for three of the four DOACs, which in acute cases can be used in addition to prothrombin complex concentrates and fresh frozen plasma to normalize coagulation.
{"title":"[Perioperative management of platelet function and anticoagulation in geriatric patients].","authors":"Romana Lenzen-Großimlinghaus","doi":"10.1007/s00104-021-01521-7","DOIUrl":"https://doi.org/10.1007/s00104-021-01521-7","url":null,"abstract":"<p><p>Geriatric patients often have cardiovascular diseases that require differentiated perioperative management of hemostasis. The operation-related bleeding risk and the individual thromboembolism risk mutually influence each other, so that a differentiated preoperative assessment of the further prescription of coagulation-modulating medication is required. In many cases the active coagulation medication can be interrupted without replacement or continued unchanged. In cardiovascular diseases with antiplatelet medication, the preoperative risk-benefit assessment for most operations leads to the continuation of previous platelet aggregation inhibitor monotherapy; however, if there is a high risk of cardiovascular thromboembolism with dual platelet inhibition, the individual perioperative medication should be closely coordinated with a geriatrician or cardiologist.In most cases, the intake of vitamin K antagonists (VKA) can be preoperatively interrupted. In cases of high risk of thromboembolism, a temporary bridging with heparin must be carried out. The introduction of the four new direct oral antagonists (DOAC) has made the perioperative management of anticoagulation much easier. Bridging with heparin is not necessary. Perioperatively, only the dosage and timing of interruption of the DOACs have to be determined individually depending on the operative bleeding risk as well as the age, body weight and kidney function of the patient. If bleeding complications arise under the influence of the DOACs, antidotes are available for three of the four DOACs, which in acute cases can be used in addition to prothrombin complex concentrates and fresh frozen plasma to normalize coagulation.</p>","PeriodicalId":50700,"journal":{"name":"Chirurg","volume":"93 3","pages":"266-273"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39556222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}