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[What (general/abdominal) surgeons should know about occupational medicine? : General vaccine recommendations and postexposure prophylaxis of hepatitis B, C and HIV]. 关于职业医学,(普通外科医生/腹部外科医生)应该知道些什么?:乙肝、丙肝和艾滋病毒的一般疫苗建议和接触后预防]。
4区 医学 Q3 Medicine Pub Date : 2022-02-01 Epub Date: 2021-09-15 DOI: 10.1007/s00104-021-01502-w
Beatrice Thielmann, Frank Meyer, Irina Böckelmann

This article deals with the general recommendations on vaccination and postexposure prophylaxis, which can be utilized for cuts and needlestick injuries. Cuts and needlestick injuries among surgeons are common occupational accidents. These should be interpreted as acute or emergency situations, especially if there was contact with infectious index patients or the danger of infection cannot be excluded. This results in high economic costs but also in the individual confrontation with an infectious disease that is definitely incurable. The aim of this review is to highlight the general and occupational vaccine recommendations for surgeons. In addition, background information and legal principles are presented. There is a duty to provide and to obtain information about effective protective measures against infectious diseases from cuts and needlestick injuries even for surgeons. In addition, primary prophylaxis, vaccination recommendations, and postexposure prophylaxis after cuts and needlestick injuries as well as the TOP principle are presented. The TOP principle comprises technical, organizational and person-related protective measures.

本文讨论了关于疫苗接种和暴露后预防的一般建议,这些建议可用于割伤和针刺伤。外科医生的割伤和针刺伤是常见的职业事故。这些应被解释为急性或紧急情况,特别是如果与感染指数患者有接触或不能排除感染危险。这不仅造成了高昂的经济成本,而且还使个人面临着一种绝对无法治愈的传染病。本综述的目的是强调外科医生的一般和职业疫苗建议。此外,还介绍了背景资料和法律原则。有义务提供和获取有关有效保护措施的信息,防止因割伤和针刺而感染传染病,即使对外科医生也是如此。此外,还介绍了初级预防、疫苗接种建议、割伤和针刺伤后暴露后预防以及TOP原则。TOP原则包括技术、组织和与人有关的保护措施。
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引用次数: 0
[Association between time to surgery and colon cancer survival in the United States]. [在美国,手术时间与结肠癌存活率之间的关系]。
4区 医学 Q3 Medicine Pub Date : 2022-02-01 Epub Date: 2022-01-13 DOI: 10.1007/s00104-021-01565-9
S Axt, M Anthuber
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引用次数: 0
[ASCO guidelines for the management of stage III NSCLC part 1: staging]. [ASCO III期NSCLC管理指南第1部分:分期]。
4区 医学 Q3 Medicine Pub Date : 2022-02-01 Epub Date: 2022-01-24 DOI: 10.1007/s00104-022-01581-3
Khosro Hekmat, Christiane J Bruns
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引用次数: 0
[Complication rate after femoral shaft fractures in childhood and adolescence depending on patient factors and treatment measures]. [儿童和青少年股骨干骨折并发症发生率取决于患者因素和治疗措施]。
4区 医学 Q3 Medicine Pub Date : 2022-02-01 Epub Date: 2021-06-16 DOI: 10.1007/s00104-021-01437-2
S Oberthür, S Piatek, H Krause, H Rüther, P J Roch, A Zoch, W Lehmann, S Sehmisch, M R Klauser

Background: The treatment of pediatric femoral shaft fractures has undergone an increasing change in recent years. The previously predominant treatment procedures were extensively replaced by minimally invasive techniques (e.g. elastic stable intramedullary nailing, ESIN). The aim of this study was the comparison of complication rates depending on patient factors as well as various treatment procedures.

Material and methods: This study involved a retrospective X‑ray morphometric evaluation of data. The patient files and X‑rays of 101 children who were treated at 2 level I trauma centers were analyzed.

Results: Conservative treatment was carried out in 19% of the cases. Among the surgical procedures the ESIN technique was predominant (n = 60). Complications that needed revision occurred in 10% of the children after conservative treatment. Revision surgery had to be carried out in more than 6% of the cases in children who were surgically treated. Among the surgical procedures ESIN stabilization demonstrated the lowest revision rate with only 3%. Children under three years and adolescents had a higher risk for developing complications. If the ESIN wires used were too thin in relation to the diameter of the medullary cavity there was an increased probability of complications of around 30%.

Conclusion: This study revealed a moderate risk of complications in the treatment of femoral shaft fractures in children. The risk of complications after external fixation and conservative treatment was the highest in this study. Overall, the ESIN technique showed the lowest risk of complications. The results of this study could confirm the known limitations of the ESIN technique depending on age and body weight.

背景:近年来,小儿股骨干骨折的治疗方法发生了越来越多的变化。以前主要的治疗方法被微创技术广泛取代(例如弹性稳定髓内钉,ESIN)。本研究的目的是比较并发症的发生率取决于患者的因素和不同的治疗程序。材料和方法:本研究对资料进行回顾性X线形态计量学评价。分析了101例在2个一级创伤中心接受治疗的儿童的病历和X线照片。结果:保守治疗占19%。ESIN技术在外科手术中占主导地位(n = 60)。10%的患儿在保守治疗后出现需要翻修的并发症。在接受手术治疗的儿童中,超过6%的病例必须进行翻修手术。在外科手术中,ESIN稳定的翻修率最低,仅为3%。三岁以下儿童和青少年患并发症的风险更高。如果使用的ESIN丝相对于髓腔的直径太细,则并发症的可能性增加约30%。结论:本研究揭示了儿童股骨干骨折治疗并发症的中等风险。外固定及保守治疗后并发症风险最高。总体而言,ESIN技术显示出最低的并发症风险。本研究的结果可以证实ESIN技术在年龄和体重方面的已知局限性。
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引用次数: 2
[Complete response after neoadjuvant therapy : How certain is the pathology?] 新辅助治疗后完全缓解:病理有多确定?]
4区 医学 Q3 Medicine Pub Date : 2022-02-01 Epub Date: 2021-10-06 DOI: 10.1007/s00104-021-01510-w
Iris Tischoff, Andrea Tannapfel

Histopathologic evaluation of tumors after neoadjuvant therapy is performed by tumor regression grading (TRG) systems, which reflect the proportion of vital residual primary tumor in relation to the previous total tumor. The World Health Organization (WHO) tumor grading is replaced by TRG in tumor classification. The histopathological work-up of a tumor is based on the criteria of the TNM classification even after neoadjuvant therapy. A uniform TRG does not exist. For various tumors TRGs based on the tumor entity have been established, consisting of a 3-stage or 5‑stage grading system. Complete histopathological tumor regression is only present if no vital tumor cells are detectable in the histopathological examination of the primary surgical specimens (primary tumor and accompanying locoregional lymph nodes) and there are no distant metastases.

新辅助治疗后肿瘤的组织病理学评估是通过肿瘤回归分级(TRG)系统进行的,该系统反映了重要残余原发肿瘤与先前总肿瘤的比例。在肿瘤分类中,TRG取代了世界卫生组织(WHO)的肿瘤分级。肿瘤的组织病理学检查是基于TNM分类的标准,即使在新辅助治疗后。统一的TRG不存在。对于各种肿瘤,已经建立了基于肿瘤实体的trg,包括3期或5期的分级系统。只有在原发手术标本(原发肿瘤和伴随的局部区域淋巴结)的组织病理学检查中没有检测到重要的肿瘤细胞,并且没有远处转移时,才存在完全的组织病理学肿瘤消退。
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引用次数: 0
[What (abdominal) surgeons must know about aspects of autonomic decisions with respect to self-determination, advance healthcare directives and suicide]. [腹部外科医生在自主决定、预先医疗指示和自杀方面必须了解哪些方面]。
4区 医学 Q3 Medicine Pub Date : 2022-02-01 Epub Date: 2021-07-23 DOI: 10.1007/s00104-021-01469-8
Alfred Simon, Frank Meyer

The right of patients to self-determination has become increasingly important in recent decades. In clinical practice, it finds concrete expression in the concept of informed consent, according to which medical interventions outside of emergency situations are only permissible with the consent of the informed patient. In the event that the patient later becomes incapable of giving consent, it is possible to document the patient's own treatment wishes in a living will or to appoint a trusted person as a proxy. The right to self-determination reaches its limits where the patient demands medical measures for which there is no medical indication, which are prohibited by law or which contradict the physician's conscience. The latter applies to physician-assisted suicide, which is legally permissible but which physicians cannot be obliged to perform.

近几十年来,病人自决的权利变得越来越重要。在临床实践中,它具体体现在知情同意的概念中,根据这一概念,紧急情况以外的医疗干预只有在知情患者同意的情况下才允许。如果病人后来没有能力表示同意,可以在生前遗嘱中记录病人自己的治疗愿望,或者指定一个值得信赖的人作为代理人。在病人要求采取没有医学指征、法律禁止或违背医生良心的医疗措施时,自决权达到了极限。后者适用于医生协助自杀,这在法律上是允许的,但医生没有义务执行。
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引用次数: 0
[Thoracic and abdominal pain after esophageal resection]. [食管切除术后胸腹疼痛]。
4区 医学 Q3 Medicine Pub Date : 2022-02-01 Epub Date: 2021-08-10 DOI: 10.1007/s00104-021-01481-y
S Blaj, M Mayr, P Piso
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引用次数: 0
[Complete response after neoadjuvant therapy: how certain is radiology?] 新辅助治疗后完全缓解:放射学有多确定?]
4区 医学 Q3 Medicine Pub Date : 2022-02-01 Epub Date: 2021-12-22 DOI: 10.1007/s00104-021-01548-w
Hanna Kuzior, Michel Eisenblätter

The concept of total neoadjuvant therapy (TNT) means a paradigm shift in the treatment of patients with rectal cancer. In cases in which the TNT induced a complete clinical response (cCR), an organ preserving watch and wait therapy concept can now be provided more often; however, this increases the demand for imaging for the determination of cCR and in the subsequent follow-up. In this article, the performance of radiology in these scenarios will be evaluated and discussed. Magnetic resonance imaging (MRI) is the current standard for local assessment of the rectum with a high sensitivity for diagnosis and staging of rectal cancer, residual tumor and tumor recurrence. However, the certain exclusion of residual malignant tissue is still difficult, in particular the differentiation of residual scar tissue from vital residual tumor is only possible with low specificity and a moderate negative predictive value (NPV). The currently discussed criteria for the assessment of imaging have not yet been validated in large cohorts and are frequently subjective. An improvement of the diagnostic accuracy for identification of cCR in patients after TNT and for monitoring patients in watch and wait treatment concepts can certainly be achieved by the integration of MRI, endoscopy and endosonography as well as clinical parameters. This should enable for identification of patients with an incomplete response or local recurrence, in time for extended treatment to be initiated without relevant impact on the patient outcome.

全新辅助治疗(TNT)的概念意味着直肠癌患者治疗的范式转变。在TNT诱导完全临床反应(cCR)的病例中,现在可以更多地提供器官保存观察和等待治疗概念;然而,这增加了对确定cCR和后续随访的影像学需求。在这篇文章中,放射学在这些情况下的表现将被评估和讨论。磁共振成像(MRI)是目前直肠局部评估的标准,对直肠癌的诊断和分期、残留肿瘤和肿瘤复发具有很高的敏感性。然而,一定程度上排除残留的恶性组织仍然是困难的,特别是残留疤痕组织与重要残留肿瘤的区分只有在低特异性和中等阴性预测值(NPV)下才有可能。目前讨论的影像学评估标准尚未在大型队列中得到验证,而且往往是主观的。通过MRI、内镜、超声以及临床参数的整合,一定可以提高对TNT术后患者cCR的诊断准确性,提高观察等待治疗理念下对患者的监测。这应该能够识别不完全缓解或局部复发的患者,及时开始延长治疗,而不会对患者的预后产生相关影响。
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引用次数: 0
[Classification of intraoperative difficulty of open liver resections]. 【肝切开切除术术中难点分类】。
4区 医学 Q3 Medicine Pub Date : 2022-02-01 Epub Date: 2022-01-18 DOI: 10.1007/s00104-022-01579-x
Oliver Rohland, Michael Ardelt, Utz Settmacher
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引用次数: 0
[Results of the Limberg flap procedure in acute and chronic pilonidal abscesses]. [Limberg皮瓣治疗急慢性毛毛脓肿的结果]。
4区 医学 Q3 Medicine Pub Date : 2022-02-01 Epub Date: 2021-06-16 DOI: 10.1007/s00104-021-01439-0
Jamal Driouch, C Braumann, J Dehnst, M Ikram, G Alnammous, D Bausch, T Glatz

Background: A number of different treatment algorithms are recommended for the treatment of an acute pilonidal abscess and a chronic pilonidal sinus. While a 1-stage surgical procedure using excision or plastic reconstruction according to Limberg or Karydakis is suggested for chronic pilonidal sinus, a 2‑stage procedure is recommended for an acute pilonidal abscess. The aim of this study was to compare the results of the 1‑stage surgery with plastic reconstruction according to Limberg for acute pilonidal abscess and chronic pilonidal sinus in terms of recurrence, disorders of wound healing, inpatient length of stay and patient satisfaction.

Methods: From 2009 to 2014 a total of 39 patients were included in this prospective observational study: 21 patients with acute pilonidal abscess and 18 patients with chronic pilonidal sinus. All patients were surgically treated with a 1‑stage procedure using the Limberg flap method. The groups were compared in terms of postoperative complication rates and frequency of recurrence.

Results: Both groups were basically comparable with respect to demographic characteristics and risk factor profiles. Analysis of the postoperative results showed a comparable rate of postoperative wound healing disorders (10% vs. 17%, p = 0.647). In the group with acute pilonidal abscesses there was no recurrence during the observational period, while in the chronic pilonidal sinus group there were 2 (11%) recurrences (p = 0.206).

Conclusion: The results of the Limberg flap procedure regarding acute pilonidal abscesses were comparable to those of chronic pilonidal sinus. The results of this study show a trend to a lower risk of recurrence. The use of the Limberg flaps therefore also seems to be an adequate treatment option in an acute infection situation.

背景:许多不同的治疗算法被推荐用于治疗急性毛毛脓肿和慢性毛毛窦。根据Limberg或Karydakis的建议,对于慢性毛毛窦,建议采用一期手术切除或整形重建,而对于急性毛毛窦脓肿,建议采用二期手术。本研究的目的是比较急性毛毛脓肿和慢性毛毛窦的一期手术与Limberg整形重建在复发、伤口愈合障碍、住院时间和患者满意度方面的结果。方法:2009 - 2014年共纳入39例患者进行前瞻性观察研究,其中急性毛细脓肿21例,慢性毛细窦18例。所有患者均采用Limberg皮瓣一期手术治疗。比较两组患者术后并发症发生率和复发率。结果:两组在人口学特征和危险因素方面基本具有可比性。术后结果分析显示,两组术后伤口愈合障碍发生率相当(10%对17%,p = 0.647)。急性毛细脓肿组观察期内无复发,慢性毛细窦组2例(11%)复发(p = 0.206)。结论:Limberg皮瓣治疗急性毛毛脓肿的效果与治疗慢性毛毛窦的效果相当。这项研究的结果显示了复发风险降低的趋势。因此,在急性感染情况下,使用Limberg皮瓣似乎也是一种适当的治疗选择。
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引用次数: 1
期刊
Chirurg
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