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Major Depression and Its Recurrences: Life Course Matters. 抑郁症及其复发:生命历程至关重要。
IF 18.4 1区 心理学 Q1 PSYCHOLOGY Pub Date : 2022-02-25 DOI: 10.1146/annurev-clinpsy-072220-021440
S. Monroe, K. Harkness
Major depression is one of the most prevalent and debilitating personal and public health conditions worldwide. Less appreciated is that depression's tremendous burdens are not shared equally among all who become depressed. Some will suffer recurrences over the rest of their lives, whereas half or more will never have a recurrence. Based on these two distinctive life course prototypes, we propose a subtype distinction for research on the origins and lifetime course of major depression. A pressing goal is to determine at the time of depression's first onset who will follow which clinical trajectory. The lack of recognition of this distinction has resulted in many obstacles, including conceptual biases, methodological oversights, and definitional dead ends. Current theories are reviewed and compared. The implications for contemporary diagnostic controversies, reevaluating research on treatment and prevention, and enhancing the predictive strength of traditionally weak indicators of recurrences and recurrent depression are discussed. Expected final online publication date for the Annual Review of Clinical Psychology, Volume 18 is May 2022. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.
重度抑郁症是世界上最普遍和最使人衰弱的个人和公共健康状况之一。人们较少认识到的是,抑郁症带来的巨大负担并不是所有抑郁症患者都能平等分担的。有些人会在他们的余生中复发,而一半或更多的人永远不会复发。基于这两种截然不同的生命历程原型,我们提出了重性抑郁症起源和生命历程研究的亚型区分。一个紧迫的目标是在抑郁症首次发作时确定谁将遵循哪种临床轨迹。缺乏对这种区别的认识导致了许多障碍,包括概念上的偏见、方法上的疏忽和定义上的死胡同。对目前的理论进行了回顾和比较。讨论了对当代诊断争议的影响,重新评估治疗和预防研究,以及提高复发和复发性抑郁症传统薄弱指标的预测强度。《临床心理学年度评论》第18卷预计最终在线出版日期为2022年5月。修订后的估计数请参阅http://www.annualreviews.org/page/journal/pubdates。
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引用次数: 46
The Biopsychosocial Puzzle of Painful Sex. 痛苦性爱的生物心理社会难题。
IF 18.4 1区 心理学 Q1 PSYCHOLOGY Pub Date : 2022-02-25 DOI: 10.1146/annurev-clinpsy-072720-014549
M. Meana, Y. Binik
Genital pain associated with sex is a prevalent and distressing problem with a complex research and clinical profile. This article reviews the historical context of the "sexual pain disorders" and the circuitous trajectory that has led from the first mention of painful sex in ancient documents to the latest diagnostic category of genito-pelvic pain penetration disorder in the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders as well as in other existing and proposed nomenclatures. Prominent etiologic research and emergent theoretical models are critically assessed, as is the latest treatment outcome research of note. Finally, the review points to a number of extant needs in the research and clinical effort, including an integrated biopsychosocial and multidisciplinary approach, randomized clinical trials, targeting of treatment barriers, and expansion of the entire enterprise to include populations that have not been considered. Expected final online publication date for the Annual Review of Clinical Psychology, Volume 18 is May 2022. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.
与性有关的生殖器疼痛是一个普遍存在的令人痛苦的问题,研究和临床情况都很复杂。本文回顾了“性疼痛障碍”的历史背景,以及从古代文献中首次提到疼痛性行为到《精神疾病诊断与统计手册》第五版以及其他现有和拟议的术语中最新诊断类别生殖器盆腔疼痛渗透障碍的迂回轨迹。对突出的病因研究和新兴的理论模型进行了批判性评估,最新的治疗结果研究也值得注意。最后,该综述指出了研究和临床工作中的一些现存需求,包括综合的生物-心理-社会和多学科方法、随机临床试验、针对治疗障碍,以及将整个企业扩展到未考虑的人群。《临床心理学年度评论》第18卷预计最终在线出版日期为2022年5月。请参阅http://www.annualreviews.org/page/journal/pubdates用于修订估算。
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引用次数: 1
Psychosocial Treatments for Bipolar Disorder in Children and Adolescents. 儿童和青少年双相情感障碍的社会心理治疗。
IF 18.4 1区 心理学 Q1 PSYCHOLOGY Pub Date : 2022-02-25 DOI: 10.1146/annurev-clinpsy-072220-021237
Haley M. Brickman, M. Fristad
Evidence suggests that adjunctive psychosocial intervention for the treatment of pediatric bipolar spectrum disorders (BPSDs) is effective, feasible, and highly accepted as both an acute and maintenance treatment for youth with BPSD diagnoses as well as a preventive treatment for high-risk youth who are either asymptomatic or exhibit subsyndromal mood symptoms. Here, we provide a comprehensive review of all known evidence-based interventions, including detailed descriptions of treatment targets and core components, results of clinical trials, and updated research on mediators and moderators of treatment efficacy. Treatments are presented systematically according to level of empirical support (i.e., well established, probably efficacious, possibly efficacious, experimental, or questionable); upcoming and ongoing trials are included when possible. In line with a staging approach, preventive interventions are presented separately. Recommendations for best practices based on age, stage, and additional evidence-based child and family factors shown to affect treatment outcomes are provided. Expected final online publication date for the Annual Review of Clinical Psychology, Volume 18 is May 2022. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.
有证据表明,辅助心理社会干预治疗儿童双相情感障碍(BPSD)是有效的、可行的,并且被高度接受,既可以作为诊断为BPSD的青少年的急性和维持治疗,也可以作为无症状或表现为亚综合征情绪症状的高危青少年的预防性治疗。在此,我们对所有已知的循证干预措施进行了全面回顾,包括对治疗目标和核心成分的详细描述,临床试验结果,以及对治疗疗效的介质和调节因子的最新研究。根据经验支持的水平系统地提出治疗方法(即,已建立的,可能有效的,可能有效的,实验性的或可疑的);如果可能,将包括即将进行和正在进行的试验。按照分期方法,预防性干预措施分别提出。提供了基于年龄、阶段和其他循证儿童和家庭因素的最佳实践建议,这些因素显示会影响治疗结果。《临床心理学年度评论》第18卷预计最终在线出版日期为2022年5月。修订后的估计数请参阅http://www.annualreviews.org/page/journal/pubdates。
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引用次数: 5
Training the Next Generation of Clinical Psychological Scientists: A Data-Driven Call to Action. 培养下一代临床心理科学家:数据驱动的行动号召。
IF 18.4 1区 心理学 Q1 PSYCHOLOGY Pub Date : 2021-09-28 DOI: 10.31234/osf.io/xq538
D. Gee, K. DeYoung, K. McLaughlin, R. Tillman, D. Barch, E. Forbes, R. Krueger, T. Strauman, Mariann R Weierich, A. Shackman
The central goal of clinical psychology is to reduce the suffering caused by mental health conditions. Anxiety, mood, psychosis, substance use, personality, and other mental disorders impose an immense burden on global public health and the economy. Tackling this burden will require the development and dissemination of intervention strategies that are more effective, sustainable, and equitable. Clinical psychology is uniquely poised to serve as a transdisciplinary hub for this work. But rising to this challenge requires an honest reckoning with the strengths and weaknesses of current training practices. Building on new data, we identify the most important challenges to training the next generation of clinical scientists. We provide specific recommendations for the full spectrum of stakeholders-from funders, accreditors, and universities to program directors, faculty, and students-with an emphasis on sustainable solutions that promote scientific rigor and discovery and enhance the mental health of clinical scientists and the public alike. Expected final online publication date for the Annual Review of Clinical Psychology, Volume 18 is May 2022. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.
临床心理学的中心目标是减少心理健康状况造成的痛苦。焦虑、情绪、精神病、药物使用、人格和其他精神障碍给全球公共卫生和经济带来了巨大负担。解决这一负担需要制定和传播更有效、可持续和公平的干预战略。临床心理学作为这项工作的跨学科中心是独一无二的。但应对这一挑战需要诚实地思考当前训练实践的优势和劣势。在新数据的基础上,我们确定了培养下一代临床科学家的最重要挑战。我们为从资助者、认证机构和大学到项目主任、教员和学生的所有利益相关者提供具体建议,重点是可持续的解决方案,以促进科学严谨性和发现,并增强临床科学家和公众的心理健康。《临床心理学年度评论》第18卷预计最终在线出版日期为2022年5月。请参阅http://www.annualreviews.org/page/journal/pubdates用于修订估算。
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引用次数: 11
Designing Evidence-Based Preventive Interventions That Reach More People, Faster, and with More Impact in Global Contexts. 设计基于证据的预防干预措施,在全球范围内更快、更具影响力地惠及更多人。
IF 18.4 1区 心理学 Q1 PSYCHOLOGY Pub Date : 2021-05-07 DOI: 10.1146/annurev-clinpsy-081219-120453
Mary Jane Rotheram-Borus

This article demonstrates the substantial similarities globally among preventive, evidence-based interventions (EBIs) designed to address HIV by providing four examples: an HIV family-focused intervention, the Community Popular Opinion Leader intervention, a South African maternal/child health program, and an EBI for sex workers in India. Each identified the key problems in the target population, utilized well-established social cognitive theories, created processes for engaging the target population, set standards for staff accountability, and included routine data collection to facilitate iterative program improvements over time. Building EBIs based on these common, robust features is an alternative design strategy to replication with fidelity. These components provide a road map for researchers, especially those using new technologies, and for local providers seeking to deliver EBIs that match their clients' and communities' needs. Technology platforms and community organizations may serve as resources for designers of the next generation of EBIs, offering an alternative to repeatedly validating the same interventions and replicating them with fidelity.

本文通过提供四个例子,展示了全球范围内旨在应对艾滋病毒的预防性循证干预措施(EBI)的实质性相似性:以艾滋病毒家庭为重点的干预措施、社区民意领袖干预措施、南非妇幼保健计划和印度性工作者的EBI。每一项都确定了目标人群中的关键问题,利用了公认的社会认知理论,创建了参与目标人群的流程,制定了员工问责制标准,并包括常规数据收集,以促进随着时间的推移不断改进计划。基于这些常见的、健壮的功能构建EBI是一种替代保真复制的设计策略。这些组成部分为研究人员,特别是那些使用新技术的研究人员,以及寻求提供符合客户和社区需求的息税前利润的当地供应商提供了路线图。技术平台和社区组织可以作为下一代EBI设计者的资源,为重复验证相同的干预措施并忠实地复制它们提供了一种替代方案。
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引用次数: 4
Clinical and Translational Implications of an Emerging Developmental Substructure for Autism. 新出现的自闭症发育结构对临床和转化的影响。
IF 17.8 1区 心理学 Q1 PSYCHOLOGY Pub Date : 2021-05-07 Epub Date: 2021-02-12 DOI: 10.1146/annurev-clinpsy-081219-110503
John N Constantino, Tony Charman, Emily J H Jones

A vast share of the population-attributable risk for autism relates to inherited polygenic risk. A growing number of studies in the past five years have indicated that inherited susceptibility may operate through a finite number of early developmental liabilities that, in various permutations and combinations, jointly predict familial recurrence of the convergent syndrome of social communication disability that defines the condition. Here, we synthesize this body of research to derive evidence for a novel developmental substructure for autism, which has profound implications for ongoing discovery efforts to elucidate its neurobiological causes, and to inform future clinical and biomarker studies, early interventions, and personalized approaches to therapy.

在自闭症的人口可归因风险中,有很大一部分与遗传多基因风险有关。过去五年中,越来越多的研究表明,遗传易感性可能是通过有限数量的早期发育缺陷产生的,这些缺陷通过不同的排列和组合,共同预示着自闭症家族性复发的社会交往障碍综合征。在这里,我们综合了这些研究成果,得出了自闭症新型发育亚结构的证据,这对目前阐明自闭症神经生物学病因的探索工作具有深远影响,并为未来的临床和生物标志物研究、早期干预和个性化治疗方法提供了依据。
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引用次数: 0
Personalized Models of Psychopathology. 精神病理学的个性化模型。
IF 18.4 1区 心理学 Q1 PSYCHOLOGY Pub Date : 2020-05-07 Epub Date: 2020-02-18 DOI: 10.1146/annurev-clinpsy-102419-125032
Aidan G C Wright, William C Woods

The personalized approach to psychopathology conceptualizes mental disorder as a complex system of contextualized dynamic processes that is nontrivially specific to each individual, and it seeks to develop formal idiographic statistical models to represent these individual processes. Although the personalized approach draws on long-standing influences in clinical psychology, there has been an explosion of research in recent years following the development of intensive longitudinal data capture and statistical techniques that facilitate modeling of the dynamic processes of each individual's pathology. Advances are also making idiographic analyses scalable and generalizable. We review emerging research using the personalized approach in descriptive psychopathology, precision assessment, and treatment selection and tailoring, and we identify future challenges and areas in need of additional research. The personalized approach to psychopathology holds promise to resolve thorny diagnostic issues, generate novel insights, and improve the timing and efficacy of interventions.

精神病理学的个性化方法将精神障碍概念化为一个复杂的情境化动态过程系统,该系统对每个个体都具有非寻常的特异性,并且它寻求发展正式的具体统计模型来代表这些个体过程。尽管个性化方法在临床心理学中有着长期的影响,但近年来,随着密集的纵向数据捕获和统计技术的发展,促进了每个个体病理动态过程的建模,研究也出现了爆炸式增长。进步也使具体分析可扩展和推广。我们回顾了在描述性精神病理学、精确评估、治疗选择和剪裁方面使用个性化方法的新兴研究,并确定了未来的挑战和需要进一步研究的领域。精神病理学的个性化方法有望解决棘手的诊断问题,产生新的见解,并改善干预的时机和效果。
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引用次数: 0
Prevention and Management of Childhood Obesity and Its Psychological and Health Comorbidities. 儿童肥胖及其心理和健康合并症的预防和管理。
IF 18.4 1区 心理学 Q1 PSYCHOLOGY Pub Date : 2020-05-07 Epub Date: 2020-02-25 DOI: 10.1146/annurev-clinpsy-100219-060201
Justin D Smith, Emily Fu, Marissa A Kobayashi

Childhood obesity has become a global pandemic in developed countries, leading to a host of medical conditions that contribute to increased morbidity and premature death. The causes of obesity in childhood and adolescence are complex and multifaceted, presenting researchers and clinicians with myriad challenges in preventing and managing the problem. This article reviews the state of the science for understanding the etiology of childhood obesity, the preventive interventions and treatment options for overweight and obesity, and the medical complications and co-occurring psychological conditions that result from excess adiposity, such as hypertension, nonalcoholic fatty liver disease, and depression. Interventions across the developmental span, varying risk levels, and service contexts (e.g.,community, school, home, health care systems) are reviewed. Future directions for research are offered with an emphasis on translational issues for taking evidence-based interventions to scale in a manner that will reduce the public health burden of the childhood obesity pandemic.

在发达国家,儿童肥胖已成为一种全球性流行病,导致许多疾病,导致发病率增加和过早死亡。儿童和青少年肥胖的原因是复杂和多方面的,给研究人员和临床医生在预防和管理这个问题方面提出了无数的挑战。这篇文章回顾了了解儿童肥胖病因的科学现状,超重和肥胖的预防干预和治疗方案,以及由过度肥胖引起的医学并发症和共存的心理状况,如高血压、非酒精性脂肪肝和抑郁症。在整个发展跨度,不同的风险水平和服务环境(例如,社区,学校,家庭,卫生保健系统)的干预措施进行了审查。提出了未来的研究方向,重点是采取以证据为基础的干预措施的转化问题,以减轻儿童肥胖流行病的公共卫生负担。
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引用次数: 0
Intergenerational Transmission of Depression. 抑郁症的代际传递。
IF 18.4 1区 心理学 Q1 PSYCHOLOGY Pub Date : 2020-05-07 Epub Date: 2020-01-21 DOI: 10.1146/annurev-clinpsy-071519-113915
Sherryl H Goodman

The study of depression in mothers in relation to transmission of risk for the development of psychopathology in their children relies on solid foundations in the understanding of psychopathology, of development, and of developmental psychopathology per se. This article begins with a description of the scope of the problem, including a summary of knowledge of how mothers' depression is associated with outcomes in children and of moderators of those associations. The sense of scope then informs a theoretical and empirical perspective on knowledge of mechanisms in those associations, with a focus on what has been learned in the past 20 years. Throughout the article, and in conclusions at the end, are suggestions for next steps in research and practice.

对母亲抑郁与子女精神病理发展风险传递的关系的研究,依赖于对精神病理学、发展和发展精神病理学本身的理解。这篇文章首先描述了这个问题的范围,包括对母亲抑郁是如何与孩子的结果相关联的知识的总结,以及这些关联的调节因子。然后,范围感告知了这些关联机制知识的理论和经验观点,重点是过去20年所学到的知识。在全文和结束语中,对下一步的研究和实践提出了建议。
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引用次数: 97
Behavioral Conceptualization and Treatment of Chronic Pain. 慢性疼痛的行为概念和治疗。
IF 18.4 1区 心理学 Q1 PSYCHOLOGY Pub Date : 2020-05-07 Epub Date: 2019-12-10 DOI: 10.1146/annurev-clinpsy-050718-095744
Johan W S Vlaeyen, Geert Crombez

Pain is considered a hardwired signal of bodily disturbance belonging to a basic motivational system that urges the individual to act and to restore the body's integrity, rather than just a sensory and emotional experience. Given its eminent survival value, pain is a strong motivator for learning. Response to repeated pain increases when harm risks are high (sensitization) and decreases in the absence of such risks (habituation). Discovering relations between pain and other events provides the possibility to predict (Pavlovian conditioning) and control (operant conditioning) harmful events. Avoidance is adaptive in the short term but paradoxically may have detrimental long-term effects. Pain and pain-related responses compete with other demands in the environment. Exposure-based treatments share the aim of facilitating or restoring the pursuit of individual valued life goals in the face of persistent pain, and further improvements in pain treatment may require a paradigm shift toward more personalized approaches.

疼痛被认为是一种身体紊乱的固有信号,属于一个基本的动机系统,它促使个人采取行动,恢复身体的完整性,而不仅仅是一种感觉和情感体验。考虑到其显著的生存价值,疼痛是学习的强大动力。当伤害风险高时,对反复疼痛的反应会增加(致敏),而在没有这种风险时,对疼痛的反应会减少(习惯化)。发现疼痛和其他事件之间的关系提供了预测(巴甫洛夫条件反射)和控制(操作性条件反射)有害事件的可能性。逃避在短期内是适应性的,但矛盾的是,它可能会产生有害的长期影响。疼痛和与疼痛相关的反应与环境中的其他需求相竞争。暴露治疗的目的是促进或恢复个体在面对持续疼痛时对有价值的生活目标的追求,进一步改善疼痛治疗可能需要向更个性化的方法转变。
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引用次数: 52
期刊
Annual Review of Clinical Psychology
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