首页 > 最新文献

Annual Review of Clinical Psychology最新文献

英文 中文
Interventions for Couples. 夫妇干预。
IF 18.4 1区 心理学 Q1 PSYCHOLOGY Pub Date : 2020-05-07 Epub Date: 2020-02-07 DOI: 10.1146/annurev-clinpsy-071519-020546
Thomas N Bradbury, Guy Bodenmann
Because relationship discord and dissolution are common and costly, interventions are needed to treat distressed couples and to prevent distress among vulnerable couples. We review meta-analytic evidence showing that 60-80% of distressed couples benefit from behavioral and emotion-focused approaches to couple therapy, but we also note that treatment effects are weaker in actual clinical practice than in controlled studies, dissipate following treatment for about half of all couples, and may be explained by factors that are common across models. Meta-analyses of prevention programs reveal reliable but smaller effects, reflecting a need to know more about whether and how communication mediates effects, about how risk and diversity moderate effects, and about how technology-enabled interventions can reduce attrition in vulnerable populations. Interventions for couples are improving and expanding, but critical questions remain about how and for whom they work. Expected final online publication date for the Annual Review of Clinical Psychology, Volume 16 is May 7, 2020. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.
由于关系不和和破裂是常见的和昂贵的,干预需要治疗痛苦的夫妇和防止痛苦的脆弱的夫妇。我们回顾了荟萃分析证据,表明60-80%的痛苦夫妇受益于以行为和情绪为重点的夫妻治疗方法,但我们也注意到,实际临床实践中的治疗效果比对照研究弱,大约一半的夫妇在治疗后消失,这可能是由模型中常见的因素来解释的。对预防项目的荟萃分析显示了可靠但较小的效果,反映出需要更多地了解沟通是否以及如何调节效果,风险和多样性如何调节效果,以及技术支持的干预措施如何减少弱势群体的流失。针对夫妇的干预措施正在改善和扩大,但关键的问题仍然是如何以及为谁工作。
{"title":"Interventions for Couples.","authors":"Thomas N Bradbury, Guy Bodenmann","doi":"10.1146/annurev-clinpsy-071519-020546","DOIUrl":"https://doi.org/10.1146/annurev-clinpsy-071519-020546","url":null,"abstract":"Because relationship discord and dissolution are common and costly, interventions are needed to treat distressed couples and to prevent distress among vulnerable couples. We review meta-analytic evidence showing that 60-80% of distressed couples benefit from behavioral and emotion-focused approaches to couple therapy, but we also note that treatment effects are weaker in actual clinical practice than in controlled studies, dissipate following treatment for about half of all couples, and may be explained by factors that are common across models. Meta-analyses of prevention programs reveal reliable but smaller effects, reflecting a need to know more about whether and how communication mediates effects, about how risk and diversity moderate effects, and about how technology-enabled interventions can reduce attrition in vulnerable populations. Interventions for couples are improving and expanding, but critical questions remain about how and for whom they work. Expected final online publication date for the Annual Review of Clinical Psychology, Volume 16 is May 7, 2020. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.","PeriodicalId":50755,"journal":{"name":"Annual Review of Clinical Psychology","volume":"16 ","pages":"99-123"},"PeriodicalIF":18.4,"publicationDate":"2020-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1146/annurev-clinpsy-071519-020546","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37621544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 26
Creativity and Bipolar Disorder: A Shared Genetic Vulnerability. 创造力和双相情感障碍:共同的遗传脆弱性。
IF 18.4 1区 心理学 Q1 PSYCHOLOGY Pub Date : 2020-05-07 Epub Date: 2020-02-10 DOI: 10.1146/annurev-clinpsy-050718-095449
Tiffany A Greenwood

Bipolar disorder is a lifelong mood disorder characterized by extreme mood swings between mania and depression. Despite fitness costs associated with increased mortality and significant impairment, bipolar disorder has persisted in the population with a high heritability and a stable prevalence. Creativity and other positive traits have repeatedly been associated with the bipolar spectrum, particularly among unaffected first-degree relatives and those with milder expressions of bipolar traits. This suggests a model in which large doses of risk variants cause illness, but mild to moderate doses confer advantages, which serve to maintain bipolar disorder in the population. Bipolar disorder may thus be better conceptualized as a dimensional trait existing at the extreme of normal population variation in positive temperament, personality, and cognitive traits, aspects of which may reflect a shared vulnerability with creativity. Investigations of this shared vulnerability may provide insight into the genetic mechanisms underlying illness and suggest novel treatments.

双相情感障碍是一种以躁狂症和抑郁症之间的极端情绪波动为特征的终身情绪障碍。尽管健身成本与死亡率增加和显著损伤相关,但双相情感障碍在人群中持续存在,具有高遗传性和稳定的患病率。创造力和其他积极的特征一再与双相情感障碍谱系联系在一起,特别是在未受影响的一级亲属和双相情感障碍特征表达较轻的人之间。这表明了一种模型,在这种模型中,大剂量的风险变异会导致疾病,但轻度到中度的剂量会带来优势,这有助于维持人群中的双相情感障碍。因此,双相情感障碍可能被更好地概念化为存在于正常人群在积极气质、个性和认知特征方面极端变化的一种维度特征,这些特征的某些方面可能反映了与创造力共同的脆弱性。对这一共同弱点的调查可能会为疾病的遗传机制提供见解,并提出新的治疗方法。
{"title":"Creativity and Bipolar Disorder: A Shared Genetic Vulnerability.","authors":"Tiffany A Greenwood","doi":"10.1146/annurev-clinpsy-050718-095449","DOIUrl":"https://doi.org/10.1146/annurev-clinpsy-050718-095449","url":null,"abstract":"<p><p>Bipolar disorder is a lifelong mood disorder characterized by extreme mood swings between mania and depression. Despite fitness costs associated with increased mortality and significant impairment, bipolar disorder has persisted in the population with a high heritability and a stable prevalence. Creativity and other positive traits have repeatedly been associated with the bipolar spectrum, particularly among unaffected first-degree relatives and those with milder expressions of bipolar traits. This suggests a model in which large doses of risk variants cause illness, but mild to moderate doses confer advantages, which serve to maintain bipolar disorder in the population. Bipolar disorder may thus be better conceptualized as a dimensional trait existing at the extreme of normal population variation in positive temperament, personality, and cognitive traits, aspects of which may reflect a shared vulnerability with creativity. Investigations of this shared vulnerability may provide insight into the genetic mechanisms underlying illness and suggest novel treatments.</p>","PeriodicalId":50755,"journal":{"name":"Annual Review of Clinical Psychology","volume":"16 ","pages":"239-264"},"PeriodicalIF":18.4,"publicationDate":"2020-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1146/annurev-clinpsy-050718-095449","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37628813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 25
Stress and Psychiatric Disorders: The Role of Mitochondria. 应激与精神疾病:线粒体的作用。
IF 18.4 1区 心理学 Q1 PSYCHOLOGY Pub Date : 2020-05-07 Epub Date: 2020-02-24 DOI: 10.1146/annurev-clinpsy-082719-104030
Teresa E Daniels, Elizabeth M Olsen, Audrey R Tyrka

In seeking to understand mental health and disease, it is fundamental to identify the biological substrates that draw together the experiences and physiological processes that underlie observed psychological changes. Mitochondria are subcellular organelles best known for their central role in energetics, producing adenosine triphosphate to power most cellular processes. Converging lines of evidence indicate that mitochondria play a key role in the biological embedding of adversity. Preclinical research documents the effects of stress exposure on mitochondrial structure and function, and recent human research suggests alterations constituting recalibrations, both adaptive and nonadaptive. Current research suggests dynamic relationships among stress exposure, neuroendocrine signaling, inflammation, and mitochondrial function. These complex relationships are implicated in disease risk, and their elucidation may inform prevention and treatment of stress- and trauma-related disorders. We review and evaluate the evidence for mitochondrial dysfunction as a consequence of stress exposure and as a contributing factor to psychiatric disease.

在寻求了解心理健康和疾病的过程中,确定将观察到的心理变化背后的经验和生理过程结合在一起的生物基础是至关重要的。线粒体是亚细胞细胞器,以其在能量学中的核心作用而闻名,产生三磷酸腺苷,为大多数细胞过程提供动力。越来越多的证据表明,线粒体在逆境的生物嵌入中起着关键作用。临床前研究记录了应激暴露对线粒体结构和功能的影响,最近的人类研究表明,适应性和非适应性的改变构成了重新校准。目前的研究表明,应激暴露、神经内分泌信号、炎症和线粒体功能之间存在动态关系。这些复杂的关系与疾病风险有关,它们的阐明可能为预防和治疗压力和创伤相关疾病提供信息。我们回顾和评估线粒体功能障碍作为压力暴露的结果和作为精神疾病的一个促成因素的证据。
{"title":"Stress and Psychiatric Disorders: The Role of Mitochondria.","authors":"Teresa E Daniels,&nbsp;Elizabeth M Olsen,&nbsp;Audrey R Tyrka","doi":"10.1146/annurev-clinpsy-082719-104030","DOIUrl":"https://doi.org/10.1146/annurev-clinpsy-082719-104030","url":null,"abstract":"<p><p>In seeking to understand mental health and disease, it is fundamental to identify the biological substrates that draw together the experiences and physiological processes that underlie observed psychological changes. Mitochondria are subcellular organelles best known for their central role in energetics, producing adenosine triphosphate to power most cellular processes. Converging lines of evidence indicate that mitochondria play a key role in the biological embedding of adversity. Preclinical research documents the effects of stress exposure on mitochondrial structure and function, and recent human research suggests alterations constituting recalibrations, both adaptive and nonadaptive. Current research suggests dynamic relationships among stress exposure, neuroendocrine signaling, inflammation, and mitochondrial function. These complex relationships are implicated in disease risk, and their elucidation may inform prevention and treatment of stress- and trauma-related disorders. We review and evaluate the evidence for mitochondrial dysfunction as a consequence of stress exposure and as a contributing factor to psychiatric disease.</p>","PeriodicalId":50755,"journal":{"name":"Annual Review of Clinical Psychology","volume":"16 ","pages":"165-186"},"PeriodicalIF":18.4,"publicationDate":"2020-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1146/annurev-clinpsy-082719-104030","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37672399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 46
Accounting for Confounding in Observational Studies. 观察性研究中混淆的解释。
IF 18.4 1区 心理学 Q1 PSYCHOLOGY Pub Date : 2020-05-07 DOI: 10.1146/annurev-clinpsy-032816-045030
Brian M D'Onofrio, Arvid Sjölander, Benjamin B Lahey, Paul Lichtenstein, A Sara Öberg

The goal of this review is to enable clinical psychology researchers to more rigorously test competing hypotheses when studying risk factors in observational studies. We argue that there is a critical need for researchers to leverage recent advances in epidemiology/biostatistics related to causal inference and to use innovative approaches to address a key limitation of observational research: the need to account for confounding. We first review theoretical issues related to the study of causation, how causal diagrams can facilitate the identification and testing of competing hypotheses, and the current limitations of observational research in the field. We then describe two broad approaches that help account for confounding: analytic approaches that account for measured traits and designs that account for unmeasured factors. We provide descriptions of several such approaches and highlight their strengths and limitations, particularly as they relate to the etiology and treatment of behavioral health problems.

本综述的目的是使临床心理学研究人员在观察性研究中研究风险因素时能够更严格地检验相互竞争的假设。我们认为,研究人员迫切需要利用与因果推理相关的流行病学/生物统计学的最新进展,并使用创新的方法来解决观察性研究的一个关键限制:需要考虑混淆。我们首先回顾了与因果关系研究相关的理论问题,因果图如何促进相互竞争的假设的识别和检验,以及该领域目前观察研究的局限性。然后,我们描述了两种有助于解释混淆的广泛方法:解释测量特征的分析方法和解释未测量因素的设计方法。我们提供了几个这样的方法的描述,并强调他们的优势和局限性,特别是因为他们涉及到的病因和治疗行为健康问题。
{"title":"Accounting for Confounding in Observational Studies.","authors":"Brian M D'Onofrio,&nbsp;Arvid Sjölander,&nbsp;Benjamin B Lahey,&nbsp;Paul Lichtenstein,&nbsp;A Sara Öberg","doi":"10.1146/annurev-clinpsy-032816-045030","DOIUrl":"https://doi.org/10.1146/annurev-clinpsy-032816-045030","url":null,"abstract":"<p><p>The goal of this review is to enable clinical psychology researchers to more rigorously test competing hypotheses when studying risk factors in observational studies. We argue that there is a critical need for researchers to leverage recent advances in epidemiology/biostatistics related to causal inference and to use innovative approaches to address a key limitation of observational research: the need to account for confounding. We first review theoretical issues related to the study of causation, how causal diagrams can facilitate the identification and testing of competing hypotheses, and the current limitations of observational research in the field. We then describe two broad approaches that help account for confounding: analytic approaches that account for measured traits and designs that account for unmeasured factors. We provide descriptions of several such approaches and highlight their strengths and limitations, particularly as they relate to the etiology and treatment of behavioral health problems.</p>","PeriodicalId":50755,"journal":{"name":"Annual Review of Clinical Psychology","volume":"16 ","pages":"25-48"},"PeriodicalIF":18.4,"publicationDate":"2020-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1146/annurev-clinpsy-032816-045030","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37913880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 29
Conceptualization, History, and Future of the Paraphilias. 释义、历史和未来。
IF 18.4 1区 心理学 Q1 PSYCHOLOGY Pub Date : 2020-05-07 Epub Date: 2020-02-05 DOI: 10.1146/annurev-clinpsy-050718-095548
Charles Moser, Peggy J Kleinplatz

There is no accepted definition of the term paraphilia despite its being listed as an essential feature of a class of mental disorders known as the paraphilic disorders. The origin of the term, history of its inclusion as a diagnosis, and logical flaws inherent in the various definitions are discussed in this review. We examine the basis for pathologizing individuals with paraphilias, consider what paraphilias can tell us about how humans develop their sexual interests, and question the usefulness of dividing sexual interests into paraphilias and normophilias. The construct of the paraphilias appears to be poorly conceived and has outlived its usefulness.

尽管它被列为一种被称为性反常障碍的精神障碍的基本特征,但对“性反常”一词还没有公认的定义。本综述讨论了该术语的起源,其作为诊断的历史,以及各种定义中固有的逻辑缺陷。我们研究了有性反常行为的个体的病理基础,考虑了性反常行为可以告诉我们人类是如何发展他们的性兴趣的,并质疑将性兴趣分为性反常行为和正常恋的有效性。性偏离的构造似乎构思得很差,而且已经失去了它的用处。
{"title":"Conceptualization, History, and Future of the Paraphilias.","authors":"Charles Moser,&nbsp;Peggy J Kleinplatz","doi":"10.1146/annurev-clinpsy-050718-095548","DOIUrl":"https://doi.org/10.1146/annurev-clinpsy-050718-095548","url":null,"abstract":"<p><p>There is no accepted definition of the term paraphilia despite its being listed as an essential feature of a class of mental disorders known as the paraphilic disorders. The origin of the term, history of its inclusion as a diagnosis, and logical flaws inherent in the various definitions are discussed in this review. We examine the basis for pathologizing individuals with paraphilias, consider what paraphilias can tell us about how humans develop their sexual interests, and question the usefulness of dividing sexual interests into paraphilias and normophilias. The construct of the paraphilias appears to be poorly conceived and has outlived its usefulness.</p>","PeriodicalId":50755,"journal":{"name":"Annual Review of Clinical Psychology","volume":"16 ","pages":"379-399"},"PeriodicalIF":18.4,"publicationDate":"2020-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1146/annurev-clinpsy-050718-095548","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37612374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 13
Risk and Resilience in Minority Youth Populations. 少数民族青年人口的风险和复原力。
IF 18.4 1区 心理学 Q1 PSYCHOLOGY Pub Date : 2020-05-07 DOI: 10.1146/annurev-clinpsy-071119-115839
Amy K Marks, G Alice Woolverton, Cynthia García Coll

This review presents current theory and empirical research that address the interplay between risk and resilience processes among minority youth in the United States. To move the clinical sciences forward in their research and treatment approaches to solving minority-majority health and well-being disparities, ecological, intersectional, and emic (within-group) approaches must be adopted. We discuss the consequences of systematic oppression and marginalization for children in the United States, focusing primarily on research regarding xenophobia, discrimination, and racism. Lastly, we provide examples of recent interventions that take emic approaches to closing minority-majority gaps in developmental outcomes.

本综述提出了当前的理论和实证研究,以解决美国少数民族青年风险和弹性过程之间的相互作用。为了推动临床科学的研究和治疗方法向前发展,以解决少数人与多数人的健康和福祉差距,必须采用生态、交叉和局部(组内)方法。我们讨论了美国儿童的系统性压迫和边缘化的后果,主要集中在仇外心理、歧视和种族主义方面的研究。最后,我们提供了一些最近的干预措施的例子,这些干预措施采用了主流方法来缩小少数人与多数人在发展结果方面的差距。
{"title":"Risk and Resilience in Minority Youth Populations.","authors":"Amy K Marks,&nbsp;G Alice Woolverton,&nbsp;Cynthia García Coll","doi":"10.1146/annurev-clinpsy-071119-115839","DOIUrl":"https://doi.org/10.1146/annurev-clinpsy-071119-115839","url":null,"abstract":"<p><p>This review presents current theory and empirical research that address the interplay between risk and resilience processes among minority youth in the United States. To move the clinical sciences forward in their research and treatment approaches to solving minority-majority health and well-being disparities, ecological, intersectional, and emic (within-group) approaches must be adopted. We discuss the consequences of systematic oppression and marginalization for children in the United States, focusing primarily on research regarding xenophobia, discrimination, and racism. Lastly, we provide examples of recent interventions that take emic approaches to closing minority-majority gaps in developmental outcomes.</p>","PeriodicalId":50755,"journal":{"name":"Annual Review of Clinical Psychology","volume":"16 ","pages":"151-163"},"PeriodicalIF":18.4,"publicationDate":"2020-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1146/annurev-clinpsy-071119-115839","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37913881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 25
Epigenetics, Development, and Psychopathology. 表观遗传学、发育和精神病理学。
IF 18.4 1区 心理学 Q1 PSYCHOLOGY Pub Date : 2020-05-07 Epub Date: 2020-02-21 DOI: 10.1146/annurev-clinpsy-050718-095530
Kieran J O'Donnell, Michael J Meaney

Epigenetic mechanisms govern the transcription of the genome. Research with model systems reveals that environmental conditions can directly influence epigenetic mechanisms that are associated with interindividual differences in gene expression in brain and neural function. In this review, we provide a brief overview of epigenetic mechanisms and research with relevant rodent models. We emphasize more recent translational research programs in epigenetics as well as the challenges inherent in the integration of epigenetics into developmental and clinical psychology. Our objectives are to present an update with respect to the translational relevance of epigenetics for the study of psychopathology and to consider the state of current research with respect to its potential importance for clinical research and practice in mental health.

表观遗传机制控制着基因组的转录。模型系统研究表明,环境条件可以直接影响与个体间脑和神经功能基因表达差异相关的表观遗传机制。本文就表观遗传机制及相关啮齿动物模型的研究进展作一综述。我们强调最近的表观遗传学转化研究项目,以及将表观遗传学整合到发展和临床心理学中所固有的挑战。我们的目标是更新表观遗传学在精神病理学研究中的翻译相关性,并考虑其对心理健康临床研究和实践的潜在重要性的当前研究状态。
{"title":"Epigenetics, Development, and Psychopathology.","authors":"Kieran J O'Donnell,&nbsp;Michael J Meaney","doi":"10.1146/annurev-clinpsy-050718-095530","DOIUrl":"https://doi.org/10.1146/annurev-clinpsy-050718-095530","url":null,"abstract":"<p><p>Epigenetic mechanisms govern the transcription of the genome. Research with model systems reveals that environmental conditions can directly influence epigenetic mechanisms that are associated with interindividual differences in gene expression in brain and neural function. In this review, we provide a brief overview of epigenetic mechanisms and research with relevant rodent models. We emphasize more recent translational research programs in epigenetics as well as the challenges inherent in the integration of epigenetics into developmental and clinical psychology. Our objectives are to present an update with respect to the translational relevance of epigenetics for the study of psychopathology and to consider the state of current research with respect to its potential importance for clinical research and practice in mental health.</p>","PeriodicalId":50755,"journal":{"name":"Annual Review of Clinical Psychology","volume":"16 ","pages":"327-350"},"PeriodicalIF":18.4,"publicationDate":"2020-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1146/annurev-clinpsy-050718-095530","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37666482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 35
Social Safety Theory: A Biologically Based Evolutionary Perspective on Life Stress, Health, and Behavior. 社会安全理论:从生物学的进化角度看生活压力、健康和行为。
IF 18.4 1区 心理学 Q1 PSYCHOLOGY Pub Date : 2020-05-07 Epub Date: 2020-03-06 DOI: 10.1146/annurev-clinpsy-032816-045159
George M Slavich

Social Safety Theory hypothesizes that developing and maintaining friendly social bonds is a fundamental organizing principle of human behavior and that threats to social safety are a critical feature of psychological stressors that increase risk for disease. Central to this formulation is the fact that the human brain and immune system are principally designed to keep the body biologically safe, which they do by continually monitoring and responding to social, physical, and microbial threats in the environment. Because situations involving social conflict, isolation, devaluation, rejection, and exclusion historically increased risk for physical injury and infection, anticipatory neural-immune reactivity to social threat was likely highly conserved. This neurocognitive and immunologic ability for humans to symbolically represent and respond to potentially dangerous social situations is ultimately critical for survival. When sustained, however, this multilevel biological threat response can increase individuals' risk for viral infections and several inflammation-related disease conditions that dominate present-day morbidity and mortality.

社会安全理论(Social Safety Theory)假设,发展和维持友好的社会纽带是人类行为的基本组织原则,而对社会安全的威胁是增加疾病风险的心理压力的关键特征。这一理论的核心是,人类大脑和免疫系统的主要设计目的是保持身体的生物安全,它们通过不断监测和应对环境中的社会、物理和微生物威胁来实现这一目的。由于历史上涉及社会冲突、孤立、贬低、拒绝和排斥的情况会增加身体受伤和感染的风险,因此神经免疫系统对社会威胁的预期反应可能是高度保守的。人类的这种神经认知和免疫能力象征性地代表并应对潜在的危险社会环境,最终对生存至关重要。然而,当这种多层次的生物威胁反应持续存在时,会增加个体感染病毒和多种炎症相关疾病的风险,而这些疾病在当今的发病率和死亡率中占主导地位。
{"title":"Social Safety Theory: A Biologically Based Evolutionary Perspective on Life Stress, Health, and Behavior.","authors":"George M Slavich","doi":"10.1146/annurev-clinpsy-032816-045159","DOIUrl":"10.1146/annurev-clinpsy-032816-045159","url":null,"abstract":"<p><p>Social Safety Theory hypothesizes that developing and maintaining friendly social bonds is a fundamental organizing principle of human behavior and that threats to social safety are a critical feature of psychological stressors that increase risk for disease. Central to this formulation is the fact that the human brain and immune system are principally designed to keep the body biologically safe, which they do by continually monitoring and responding to social, physical, and microbial threats in the environment. Because situations involving social conflict, isolation, devaluation, rejection, and exclusion historically increased risk for physical injury and infection, anticipatory neural-immune reactivity to social threat was likely highly conserved. This neurocognitive and immunologic ability for humans to symbolically represent and respond to potentially dangerous social situations is ultimately critical for survival. When sustained, however, this multilevel biological threat response can increase individuals' risk for viral infections and several inflammation-related disease conditions that dominate present-day morbidity and mortality.</p>","PeriodicalId":50755,"journal":{"name":"Annual Review of Clinical Psychology","volume":"16 ","pages":"265-295"},"PeriodicalIF":18.4,"publicationDate":"2020-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7213777/pdf/nihms-1578206.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37711751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Personalized Models of Psychopathology. 精神病理学的个性化模型。
IF 18.4 1区 心理学 Q1 PSYCHOLOGY Pub Date : 2019-09-26 DOI: 10.31234/osf.io/6hqzj
A. Wright, William C. Woods
The personalized approach to psychopathology conceptualizes mental disorder as a complex system of contextualized dynamic processes that is nontrivially specific to each individual, and it seeks to develop formal idiographic statistical models to represent these individual processes. Although the personalized approach draws on long-standing influences in clinical psychology, there has been an explosion of research in recent years following the development of intensive longitudinal data capture and statistical techniques that facilitate modeling of the dynamic processes of each individual's pathology. Advances are also making idiographic analyses scalable and generalizable. We review emerging research using the personalized approach in descriptive psychopathology, precision assessment, and treatment selection and tailoring, and we identify future challenges and areas in need of additional research. The personalized approach to psychopathology holds promise to resolve thorny diagnostic issues, generate novel insights, and improve the timing and efficacy of interventions. Expected final online publication date for the Annual Review of Clinical Psychology, Volume 16 is May 7, 2020. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.
精神病理学的个性化方法将精神障碍概念化为一个复杂的情境化动态过程系统,该系统对每个个体都具有非寻常的特异性,并且它寻求发展正式的具体统计模型来代表这些个体过程。尽管个性化方法在临床心理学中有着长期的影响,但近年来,随着密集的纵向数据捕获和统计技术的发展,促进了每个个体病理动态过程的建模,研究也出现了爆炸式增长。进步也使具体分析可扩展和推广。我们回顾了在描述性精神病理学、精确评估、治疗选择和剪裁方面使用个性化方法的新兴研究,并确定了未来的挑战和需要进一步研究的领域。精神病理学的个性化方法有望解决棘手的诊断问题,产生新的见解,并改善干预的时机和效果。《临床心理学年度评论》第16卷的最终在线出版日期预计为2020年5月7日。修订后的估计数请参阅http://www.annualreviews.org/page/journal/pubdates。
{"title":"Personalized Models of Psychopathology.","authors":"A. Wright, William C. Woods","doi":"10.31234/osf.io/6hqzj","DOIUrl":"https://doi.org/10.31234/osf.io/6hqzj","url":null,"abstract":"The personalized approach to psychopathology conceptualizes mental disorder as a complex system of contextualized dynamic processes that is nontrivially specific to each individual, and it seeks to develop formal idiographic statistical models to represent these individual processes. Although the personalized approach draws on long-standing influences in clinical psychology, there has been an explosion of research in recent years following the development of intensive longitudinal data capture and statistical techniques that facilitate modeling of the dynamic processes of each individual's pathology. Advances are also making idiographic analyses scalable and generalizable. We review emerging research using the personalized approach in descriptive psychopathology, precision assessment, and treatment selection and tailoring, and we identify future challenges and areas in need of additional research. The personalized approach to psychopathology holds promise to resolve thorny diagnostic issues, generate novel insights, and improve the timing and efficacy of interventions. Expected final online publication date for the Annual Review of Clinical Psychology, Volume 16 is May 7, 2020. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.","PeriodicalId":50755,"journal":{"name":"Annual Review of Clinical Psychology","volume":"1 1","pages":""},"PeriodicalIF":18.4,"publicationDate":"2019-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47179853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 120
Estrogen, Stress, and Depression: Cognitive and Biological Interactions. 雌激素、压力和抑郁:认知和生物学的相互作用。
IF 18.4 1区 心理学 Q1 PSYCHOLOGY Pub Date : 2019-05-07 Epub Date: 2019-02-20 DOI: 10.1146/annurev-clinpsy-050718-095557
Kimberly M Albert, Paul A Newhouse

This article reviews the interactions of estrogen changes and psychosocial stress in contributing to vulnerability to major depressive disorder (MDD) in women. Estrogen modulates brain networks and processes related to changes in stress response, cognition, and emotional dysregulation that are core characteristics of MDD. Synergistic effects of estrogen on cognitive and emotional function, particularly during psychosocial stress, may underlie the association of ovarian hormone fluctuation and depression in women. We propose a model of estrogen effects on multiple brain systems that interface with stress-related emotional and cognitive processes implicated in MDD and discuss possible mechanisms through which reproductive events and changes in estrogen may contribute to MDD risk in women with other concurrent risk factors.

本文综述了雌激素变化和社会心理压力在促进女性易患重度抑郁症(MDD)中的相互作用。雌激素调节与应激反应、认知和情绪失调变化相关的大脑网络和过程,这些变化是重度抑郁症的核心特征。雌激素对认知和情绪功能的协同作用,特别是在心理社会压力期间,可能是卵巢激素波动与妇女抑郁之间关联的基础。我们提出了雌激素对多个脑系统的影响模型,这些脑系统与MDD中涉及的压力相关的情绪和认知过程相连接,并讨论了生殖事件和雌激素变化可能导致女性MDD风险的机制,以及其他并发风险因素。
{"title":"Estrogen, Stress, and Depression: Cognitive and Biological Interactions.","authors":"Kimberly M Albert,&nbsp;Paul A Newhouse","doi":"10.1146/annurev-clinpsy-050718-095557","DOIUrl":"https://doi.org/10.1146/annurev-clinpsy-050718-095557","url":null,"abstract":"<p><p>This article reviews the interactions of estrogen changes and psychosocial stress in contributing to vulnerability to major depressive disorder (MDD) in women. Estrogen modulates brain networks and processes related to changes in stress response, cognition, and emotional dysregulation that are core characteristics of MDD. Synergistic effects of estrogen on cognitive and emotional function, particularly during psychosocial stress, may underlie the association of ovarian hormone fluctuation and depression in women. We propose a model of estrogen effects on multiple brain systems that interface with stress-related emotional and cognitive processes implicated in MDD and discuss possible mechanisms through which reproductive events and changes in estrogen may contribute to MDD risk in women with other concurrent risk factors.</p>","PeriodicalId":50755,"journal":{"name":"Annual Review of Clinical Psychology","volume":"15 ","pages":"399-423"},"PeriodicalIF":18.4,"publicationDate":"2019-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1146/annurev-clinpsy-050718-095557","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36983126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 90
期刊
Annual Review of Clinical Psychology
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1