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Genome-wide association reveals a locus in neuregulin 3 associated with gabapentin efficacy in women with chronic pelvic pain 全基因组关联发现神经胶质蛋白 3 中的一个位点与加巴喷丁对慢性盆腔痛妇女的疗效有关
iScience
Pub Date : 2024-07-01 DOI: 10.1016/j.isci.2024.110370
S. C. Mackenzie, N. Rahmioglu, L. Romaniuk, Frances Collins, L. Coxon, Heather C. Whalley, Katy Vincent, K. Zondervan, A. W. Horne, Lucy H.R. Whitaker
{"title":"Genome-wide association reveals a locus in neuregulin 3 associated with gabapentin efficacy in women with chronic pelvic pain","authors":"S. C. Mackenzie, N. Rahmioglu, L. Romaniuk, Frances Collins, L. Coxon, Heather C. Whalley, Katy Vincent, K. Zondervan, A. W. Horne, Lucy H.R. Whitaker","doi":"10.1016/j.isci.2024.110370","DOIUrl":"https://doi.org/10.1016/j.isci.2024.110370","url":null,"abstract":"","PeriodicalId":508122,"journal":{"name":"iScience","volume":"49 16","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141689815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Differential Immunometabolic Responses to Delta and Omicron SARS-CoV-2 Variants in Golden Syrian Hamsters 金色叙利亚仓鼠对δ和ΩSARS-CoV-2 变体的不同免疫代谢反应
iScience
Pub Date : 2024-07-01 DOI: 10.1016/j.isci.2024.110501
Rajesh Rajaiah, K. Pandey, Arpan Acharya, Anoop T. Ambikan, Narendra Kumar, Reema Guda, Sean N. Avedissian, Luis J. Montaner, Samuel M. Cohen, U. Neogi, S. Byrareddy
{"title":"Differential Immunometabolic Responses to Delta and Omicron SARS-CoV-2 Variants in Golden Syrian Hamsters","authors":"Rajesh Rajaiah, K. Pandey, Arpan Acharya, Anoop T. Ambikan, Narendra Kumar, Reema Guda, Sean N. Avedissian, Luis J. Montaner, Samuel M. Cohen, U. Neogi, S. Byrareddy","doi":"10.1016/j.isci.2024.110501","DOIUrl":"https://doi.org/10.1016/j.isci.2024.110501","url":null,"abstract":"","PeriodicalId":508122,"journal":{"name":"iScience","volume":"62 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141695546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Androgen receptor-induced molecules and androgen contribute synergistically to male-predominance of hepatocellular carcinoma 雄激素受体诱导分子和雄激素协同导致肝细胞癌男性占主导地位
iScience
Pub Date : 2024-07-01 DOI: 10.1016/j.isci.2024.110519
Jiayi Zhao, Letian Fang, R. Pu, Wenbin Liu, Shiliang Cai, Ruihua Wang, Yiwei Shi, Zheng Li, Zihan Zhang, Zishuai Li, Guangwen Cao
{"title":"Androgen receptor-induced molecules and androgen contribute synergistically to male-predominance of hepatocellular carcinoma","authors":"Jiayi Zhao, Letian Fang, R. Pu, Wenbin Liu, Shiliang Cai, Ruihua Wang, Yiwei Shi, Zheng Li, Zihan Zhang, Zishuai Li, Guangwen Cao","doi":"10.1016/j.isci.2024.110519","DOIUrl":"https://doi.org/10.1016/j.isci.2024.110519","url":null,"abstract":"","PeriodicalId":508122,"journal":{"name":"iScience","volume":"8 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141698822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
FXN Targeting Induces Cell Death in Ovarian Cancer Stem-Like Cells Through PRDX3-Mediated Oxidative Stress FXN 靶向技术通过 PRDX3 介导的氧化应激诱导卵巢癌干样细胞死亡
iScience
Pub Date : 2024-07-01 DOI: 10.1016/j.isci.2024.110506
Shanshan Xu, Yuwan Liu, Shizhou Yang, Weidong Fei, Jiale Qin, Weiguo Lu, Junfen Xu
{"title":"FXN Targeting Induces Cell Death in Ovarian Cancer Stem-Like Cells Through PRDX3-Mediated Oxidative Stress","authors":"Shanshan Xu, Yuwan Liu, Shizhou Yang, Weidong Fei, Jiale Qin, Weiguo Lu, Junfen Xu","doi":"10.1016/j.isci.2024.110506","DOIUrl":"https://doi.org/10.1016/j.isci.2024.110506","url":null,"abstract":"","PeriodicalId":508122,"journal":{"name":"iScience","volume":"15 40","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141700090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rewiring the evolution of the human hand: How the embodiment of a virtual bionic tool improves behavior 重新连接人类手部的进化：虚拟仿生工具如何改善行为
iScience
Pub Date : 2024-06-01 DOI: 10.1016/j.isci.2024.109937
Matteo Marucci, O. Maddaluno, C. P. Ryan, Cristina Perciballi, Simona Vasta, Simone Ciotti, Alessandro Moscatelli, Viviana Betti
{"title":"Rewiring the evolution of the human hand: How the embodiment of a virtual bionic tool improves behavior","authors":"Matteo Marucci, O. Maddaluno, C. P. Ryan, Cristina Perciballi, Simona Vasta, Simone Ciotti, Alessandro Moscatelli, Viviana Betti","doi":"10.1016/j.isci.2024.109937","DOIUrl":"https://doi.org/10.1016/j.isci.2024.109937","url":null,"abstract":"","PeriodicalId":508122,"journal":{"name":"iScience","volume":"25 14","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141415236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Circulating biomarkers of kidney angiomyolipoma and cysts in tuberous sclerosis complex patients 结节性硬化症复合体患者肾脏血管脂肪瘤和囊肿的循环生物标记物
iScience
Pub Date : 2024-06-01 DOI: 10.1016/j.isci.2024.110265
V. I. Rubtsova, Y. Chun, Joohwan Kim, Cuauhtemoc B. Ramirez, Sunhee Jung, Wonsuk Choi, Miranda E. Kelly, Miranda L. Lopez, Elizabeth Cassidy, Gabrielle Rushing, Dean J. Aguiar, Wei Ling Lau, R. S. Ahdoot, Moyra Smith, A. Edinger, Sang-Guk Lee, Cholsoon Jang, Gina Lee
{"title":"Circulating biomarkers of kidney angiomyolipoma and cysts in tuberous sclerosis complex patients","authors":"V. I. Rubtsova, Y. Chun, Joohwan Kim, Cuauhtemoc B. Ramirez, Sunhee Jung, Wonsuk Choi, Miranda E. Kelly, Miranda L. Lopez, Elizabeth Cassidy, Gabrielle Rushing, Dean J. Aguiar, Wei Ling Lau, R. S. Ahdoot, Moyra Smith, A. Edinger, Sang-Guk Lee, Cholsoon Jang, Gina Lee","doi":"10.1016/j.isci.2024.110265","DOIUrl":"https://doi.org/10.1016/j.isci.2024.110265","url":null,"abstract":"","PeriodicalId":508122,"journal":{"name":"iScience","volume":"50 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141416485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vhl safeguards thymic epithelial cell identity and thymopoietic capacity by constraining Hif1a activity during development. Vhl 在发育过程中通过限制 Hif1a 的活性来保护胸腺上皮细胞的特性和胸腺造血能力。
iScience
Pub Date : 2024-06-01 DOI: 10.1016/j.isci.2024.110258
Christiane Grammer, Julia A. Komorowska, Jeremy B. Swann
{"title":"Vhl safeguards thymic epithelial cell identity and thymopoietic capacity by constraining Hif1a activity during development.","authors":"Christiane Grammer, Julia A. Komorowska, Jeremy B. Swann","doi":"10.1016/j.isci.2024.110258","DOIUrl":"https://doi.org/10.1016/j.isci.2024.110258","url":null,"abstract":"","PeriodicalId":508122,"journal":{"name":"iScience","volume":"325 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141402010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigation of a fluorescent reporter microenvironment niche labeling strategy in experimental brain metastasis 实验性脑转移中荧光报告微环境生态位标记策略的研究
iScience
Pub Date : 2024-06-01 DOI: 10.1016/j.isci.2024.110284
Matteo Massara, Bastien Dolfi, Vladimir Wischnewski, Emma Nolan, Werner Held, Ilaria Malanchi, Johanna A. Joyce
{"title":"Investigation of a fluorescent reporter microenvironment niche labeling strategy in experimental brain metastasis","authors":"Matteo Massara, Bastien Dolfi, Vladimir Wischnewski, Emma Nolan, Werner Held, Ilaria Malanchi, Johanna A. Joyce","doi":"10.1016/j.isci.2024.110284","DOIUrl":"https://doi.org/10.1016/j.isci.2024.110284","url":null,"abstract":"","PeriodicalId":508122,"journal":{"name":"iScience","volume":"57 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141399017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Humoral and cellular immune responses following Omicron BA.2.2 breakthrough infection and Omicron BA.5 reinfection Omicron BA.2.2 突破性感染和 Omicron BA.5 再感染后的体液和细胞免疫反应
iScience
Pub Date : 2024-06-01 DOI: 10.1016/j.isci.2024.110283
Xin-Jing Zhao, Bin Ji, Chao Shang, De-Yu Li, Sheng Zhang, Hong-Jing Gu, Hong-Hong Peng, Cheng Qian, Cui-Ling Zhang, Chao Shi, Yuan Shen, Jin-Jin Chen, Qiang Xu, C. Lv, B. Jiang, Hui Wang, Xiao Li, Guo-Lin Wang, Li-Qun Fang
{"title":"Humoral and cellular immune responses following Omicron BA.2.2 breakthrough infection and Omicron BA.5 reinfection","authors":"Xin-Jing Zhao, Bin Ji, Chao Shang, De-Yu Li, Sheng Zhang, Hong-Jing Gu, Hong-Hong Peng, Cheng Qian, Cui-Ling Zhang, Chao Shi, Yuan Shen, Jin-Jin Chen, Qiang Xu, C. Lv, B. Jiang, Hui Wang, Xiao Li, Guo-Lin Wang, Li-Qun Fang","doi":"10.1016/j.isci.2024.110283","DOIUrl":"https://doi.org/10.1016/j.isci.2024.110283","url":null,"abstract":"","PeriodicalId":508122,"journal":{"name":"iScience","volume":"219 S706","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141413240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ADAMTS18-fibronectin interaction regulates the morphology of liver sinusoidal endothelial cells ADAMTS18-纤连蛋白相互作用调控肝窦内皮细胞的形态
iScience
Pub Date : 2024-06-01 DOI: 10.1016/j.isci.2024.110273
Liya Wang, Li He, Weijia Yi, Min Wang, Fangmin Xu, Hanlin Liu, Jiahui Nie, Yi-Hsuan Pan, S. Dang, Wei Zhang
{"title":"ADAMTS18-fibronectin interaction regulates the morphology of liver sinusoidal endothelial cells","authors":"Liya Wang, Li He, Weijia Yi, Min Wang, Fangmin Xu, Hanlin Liu, Jiahui Nie, Yi-Hsuan Pan, S. Dang, Wei Zhang","doi":"10.1016/j.isci.2024.110273","DOIUrl":"https://doi.org/10.1016/j.isci.2024.110273","url":null,"abstract":"","PeriodicalId":508122,"journal":{"name":"iScience","volume":"77 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141412055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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