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Development of the CRISPR-Cas12a System for Editing of Pseudomonas aeruginosa Phages 开发用于编辑铜绿假单胞菌噬菌体的 CRISPR-Cas12a 系统
Pub Date : 2024-06-01 DOI: 10.1016/j.isci.2024.110210
Yibao Chen, Bingjie Yan, Weizhong Chen, Xue Zhang, Zhengjie Liu, Qing Zhang, Lulu Li, Ming Hu, Xiaonan Zhao, Xiaohui Xu, Qianghua Lv, Yanbo Luo, Yumei Cai, Yuqing Liu
{"title":"Development of the CRISPR-Cas12a System for Editing of Pseudomonas aeruginosa Phages","authors":"Yibao Chen, Bingjie Yan, Weizhong Chen, Xue Zhang, Zhengjie Liu, Qing Zhang, Lulu Li, Ming Hu, Xiaonan Zhao, Xiaohui Xu, Qianghua Lv, Yanbo Luo, Yumei Cai, Yuqing Liu","doi":"10.1016/j.isci.2024.110210","DOIUrl":"https://doi.org/10.1016/j.isci.2024.110210","url":null,"abstract":"","PeriodicalId":508122,"journal":{"name":"iScience","volume":"112 13","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141407238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nuclear NME1 enhances the malignant behavior of A549 cells and impacts lung adenocarcinoma patient prognosis 核 NME1 可增强 A549 细胞的恶性行为并影响肺腺癌患者的预后
Pub Date : 2024-06-01 DOI: 10.1016/j.isci.2024.110286
Mingfang Xu, Yingda Liu, Xunjie Kuang, Yu Pu, Yuzhu Jiang, Xiaodong Zhao, Xueqin Yang, Mengxia Li
{"title":"Nuclear NME1 enhances the malignant behavior of A549 cells and impacts lung adenocarcinoma patient prognosis","authors":"Mingfang Xu, Yingda Liu, Xunjie Kuang, Yu Pu, Yuzhu Jiang, Xiaodong Zhao, Xueqin Yang, Mengxia Li","doi":"10.1016/j.isci.2024.110286","DOIUrl":"https://doi.org/10.1016/j.isci.2024.110286","url":null,"abstract":"","PeriodicalId":508122,"journal":{"name":"iScience","volume":"29 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141408973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Differences in male Aedes aegypti and Aedes albopictus hearing systems facilitate recognition of conspecific female flight tones 雄性埃及伊蚊和白纹伊蚊听觉系统的差异有助于识别同种雌性的飞行音调
Pub Date : 2024-06-01 DOI: 10.1016/j.isci.2024.110264
YuMin M. Loh, YiFeng Y. J. Xu, Tai-Ting Lee, T. Ohashi, Yixiao D. Zhang, Daniel F. Eberl, Matthew P. Su, Azusa Kamikouchi
{"title":"Differences in male Aedes aegypti and Aedes albopictus hearing systems facilitate recognition of conspecific female flight tones","authors":"YuMin M. Loh, YiFeng Y. J. Xu, Tai-Ting Lee, T. Ohashi, Yixiao D. Zhang, Daniel F. Eberl, Matthew P. Su, Azusa Kamikouchi","doi":"10.1016/j.isci.2024.110264","DOIUrl":"https://doi.org/10.1016/j.isci.2024.110264","url":null,"abstract":"","PeriodicalId":508122,"journal":{"name":"iScience","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141392579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Experimental study on the Direct Firing of Ceramic Ware Using Concentrated Solar Energy 利用聚光太阳能直接烧制陶瓷器的实验研究
Pub Date : 2024-06-01 DOI: 10.1016/j.isci.2024.110222
Dong Guo, Hantao Liu, C. Zang, Yan wang, Feihu Sun, Dongqiang Lei, Jianfeng Wu, Huibin Zhu, Zhifeng Wang
{"title":"Experimental study on the Direct Firing of Ceramic Ware Using Concentrated Solar Energy","authors":"Dong Guo, Hantao Liu, C. Zang, Yan wang, Feihu Sun, Dongqiang Lei, Jianfeng Wu, Huibin Zhu, Zhifeng Wang","doi":"10.1016/j.isci.2024.110222","DOIUrl":"https://doi.org/10.1016/j.isci.2024.110222","url":null,"abstract":"","PeriodicalId":508122,"journal":{"name":"iScience","volume":"16 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141390359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Shipping traffic through the Arctic Ocean: spatial distribution, seasonal variation and its dependence on the sea ice extent 北冰洋航运交通:空间分布、季节变化及其与海冰范围的关系
Pub Date : 2024-06-01 DOI: 10.1016/j.isci.2024.110236
Jorge P. Rodríguez, Konstantin Klemm, Carlos M. Duarte, Víctor M. Eguíluz
{"title":"Shipping traffic through the Arctic Ocean: spatial distribution, seasonal variation and its dependence on the sea ice extent","authors":"Jorge P. Rodríguez, Konstantin Klemm, Carlos M. Duarte, Víctor M. Eguíluz","doi":"10.1016/j.isci.2024.110236","DOIUrl":"https://doi.org/10.1016/j.isci.2024.110236","url":null,"abstract":"","PeriodicalId":508122,"journal":{"name":"iScience","volume":"12 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141407763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dystrophin deficiency impairs cell junction formation during embryonic myogenesis from pluripotent stem cells 在多能干细胞胚胎肌形成过程中,肌营养不良蛋白缺乏会损害细胞连接的形成
Pub Date : 2024-06-01 DOI: 10.1016/j.isci.2024.110242
Elise Mozin, E. Massouridès, Virginie Mournetas, Clémence Lièvre, A. Bourdon, Dana L. Jackson, Jonathan S. Packer, Juyoung Seong, C. Trapnell, Caroline Le Guiner, O. Adjali, Christian Pinset, David L. Mack, J. Dupont
{"title":"Dystrophin deficiency impairs cell junction formation during embryonic myogenesis from pluripotent stem cells","authors":"Elise Mozin, E. Massouridès, Virginie Mournetas, Clémence Lièvre, A. Bourdon, Dana L. Jackson, Jonathan S. Packer, Juyoung Seong, C. Trapnell, Caroline Le Guiner, O. Adjali, Christian Pinset, David L. Mack, J. Dupont","doi":"10.1016/j.isci.2024.110242","DOIUrl":"https://doi.org/10.1016/j.isci.2024.110242","url":null,"abstract":"","PeriodicalId":508122,"journal":{"name":"iScience","volume":"77 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141391189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
VHL loss enhances anti-tumor immunity by activating the anti-viral DNA sensing pathway VHL缺失可通过激活抗病毒DNA感应途径增强抗肿瘤免疫力
Pub Date : 2024-06-01 DOI: 10.1016/j.isci.2024.110285
Meng Jiao, Mengjie Hu, Dong Pan, Xinjian Liu, Xuhui Bao, Jonathan Kim, Fang Li, Chuan-Yuan Li
{"title":"VHL loss enhances anti-tumor immunity by activating the anti-viral DNA sensing pathway","authors":"Meng Jiao, Mengjie Hu, Dong Pan, Xinjian Liu, Xuhui Bao, Jonathan Kim, Fang Li, Chuan-Yuan Li","doi":"10.1016/j.isci.2024.110285","DOIUrl":"https://doi.org/10.1016/j.isci.2024.110285","url":null,"abstract":"","PeriodicalId":508122,"journal":{"name":"iScience","volume":"5 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141396028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Machine learning on longitudinal multi-modal data enables the understanding and prognosis of Alzheimer’s disease progression 通过对纵向多模态数据的机器学习,了解阿尔茨海默病的进展情况并做出预后判断
Pub Date : 2024-06-01 DOI: 10.1016/j.isci.2024.110263
Suixia Zhang, Jing Yuan, Yu Sun, Fei Wu, Ziyue Liu, Feifei Zhai, Yaoyun Zhang, Judith Somekh, Mor Peleg, Yi-Cheng Zhu, Zhengxing Huang
{"title":"Machine learning on longitudinal multi-modal data enables the understanding and prognosis of Alzheimer’s disease progression","authors":"Suixia Zhang, Jing Yuan, Yu Sun, Fei Wu, Ziyue Liu, Feifei Zhai, Yaoyun Zhang, Judith Somekh, Mor Peleg, Yi-Cheng Zhu, Zhengxing Huang","doi":"10.1016/j.isci.2024.110263","DOIUrl":"https://doi.org/10.1016/j.isci.2024.110263","url":null,"abstract":"","PeriodicalId":508122,"journal":{"name":"iScience","volume":"25 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141395617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The profile of blood microbiome in new-onset type 1 diabetes children 新发 1 型糖尿病儿童血液微生物组的概况
Pub Date : 2024-06-01 DOI: 10.1016/j.isci.2024.110252
Xiaoxiao Yuan, Xin Yang, Zhenran Xu, Jie Li, ChengJun Sun, Ruimin Chen, Haiyan Wei, Linqi Chen, Hongwei Du, Guimei Li, Yu Yang, Xiaojuan Chen, LanWei Cui, Junfen Fu, Jing Wu, Zhihong Chen, Xin Fang, Zhe Su, Miaoying Zhang, Jing Wu, Xin Chen, Jiawei Zhou, Yue Luo, Lei Zhang, Ruirui Wang, Feihong Luo
{"title":"The profile of blood microbiome in new-onset type 1 diabetes children","authors":"Xiaoxiao Yuan, Xin Yang, Zhenran Xu, Jie Li, ChengJun Sun, Ruimin Chen, Haiyan Wei, Linqi Chen, Hongwei Du, Guimei Li, Yu Yang, Xiaojuan Chen, LanWei Cui, Junfen Fu, Jing Wu, Zhihong Chen, Xin Fang, Zhe Su, Miaoying Zhang, Jing Wu, Xin Chen, Jiawei Zhou, Yue Luo, Lei Zhang, Ruirui Wang, Feihong Luo","doi":"10.1016/j.isci.2024.110252","DOIUrl":"https://doi.org/10.1016/j.isci.2024.110252","url":null,"abstract":"","PeriodicalId":508122,"journal":{"name":"iScience","volume":"23 33","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141393383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reduced anti-viral IgG repertoire in HIV-exposed but uninfected infants compared to HIV-unexposed infants 与未感染艾滋病毒的婴儿相比,已感染艾滋病毒但未感染的婴儿体内的抗病毒 IgG 减少了
Pub Date : 2024-06-01 DOI: 10.1016/j.isci.2024.110282
Racheal Gachogo, Anna-Ursula Happel, Berenice Alinde, Clive M Gray, Heather B. Jaspan, Sonwabile Dzanibe
{"title":"Reduced anti-viral IgG repertoire in HIV-exposed but uninfected infants compared to HIV-unexposed infants","authors":"Racheal Gachogo, Anna-Ursula Happel, Berenice Alinde, Clive M Gray, Heather B. Jaspan, Sonwabile Dzanibe","doi":"10.1016/j.isci.2024.110282","DOIUrl":"https://doi.org/10.1016/j.isci.2024.110282","url":null,"abstract":"","PeriodicalId":508122,"journal":{"name":"iScience","volume":"10 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141397060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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