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Deinonychosaur trackways in southeastern China record a possible giant troodontid 中国东南部的恐龙足迹记录了一种可能的巨齿龙
Pub Date : 2024-04-01 DOI: 10.1016/j.isci.2024.109598
Lida Xing, Kecheng Niu, M. Lockley, A. Romilio, Ke Deng, W. Persons
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引用次数: 0
Mitochondrial F0F1-ATP synthase governs the induction of mitochondrial fission 线粒体 F0F1-ATP 合成酶控制着线粒体裂变的诱导过程
Pub Date : 2024-04-01 DOI: 10.1016/j.isci.2024.109808
Charlène Lhuissier, V. Desquiret-Dumas, Anaïs Girona, Jennifer Alban, Justine Faure, Julien Cassereau, Philippe Codron, Guy Lenaers, Olivier R. Baris, N. Gueguen, A. Chevrollier
{"title":"Mitochondrial F0F1-ATP synthase governs the induction of mitochondrial fission","authors":"Charlène Lhuissier, V. Desquiret-Dumas, Anaïs Girona, Jennifer Alban, Justine Faure, Julien Cassereau, Philippe Codron, Guy Lenaers, Olivier R. Baris, N. Gueguen, A. Chevrollier","doi":"10.1016/j.isci.2024.109808","DOIUrl":"https://doi.org/10.1016/j.isci.2024.109808","url":null,"abstract":"","PeriodicalId":508122,"journal":{"name":"iScience","volume":"86 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140756225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Phase 1b Study of Batiraxcept in Combination with Durvalumab in Patients with Platinum-Resistant Ovarian Cancer 铂耐药卵巢癌患者巴替拉塞与杜瓦单抗联合用药的 1b 期研究
Pub Date : 2024-04-01 DOI: 10.1016/j.isci.2024.109801
A. Knisely, Emily Hinchcliff, Elisabeth Gardiner, Reshma A. Rangwala, Kathryn Lito, B. Fellman, Ying Yuan, Anil Sood, Shannon Westin, Karen H. Lu, Amir Jazaeri
{"title":"Phase 1b Study of Batiraxcept in Combination with Durvalumab in Patients with Platinum-Resistant Ovarian Cancer","authors":"A. Knisely, Emily Hinchcliff, Elisabeth Gardiner, Reshma A. Rangwala, Kathryn Lito, B. Fellman, Ying Yuan, Anil Sood, Shannon Westin, Karen H. Lu, Amir Jazaeri","doi":"10.1016/j.isci.2024.109801","DOIUrl":"https://doi.org/10.1016/j.isci.2024.109801","url":null,"abstract":"","PeriodicalId":508122,"journal":{"name":"iScience","volume":"375 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140780263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unsupervised Clustering Identified Clinically Relevant Metabolic Syndrome Endotypes in UK and Taiwan Biobanks 无监督聚类识别英国和台湾生物库中与临床相关的代谢综合征内型
Pub Date : 2024-04-01 DOI: 10.1016/j.isci.2024.109815
Aylwin Ming Wee Lim, Evan Unit Lim, Pei-Lung Chen, Cathy Shen Jang Fann
{"title":"Unsupervised Clustering Identified Clinically Relevant Metabolic Syndrome Endotypes in UK and Taiwan Biobanks","authors":"Aylwin Ming Wee Lim, Evan Unit Lim, Pei-Lung Chen, Cathy Shen Jang Fann","doi":"10.1016/j.isci.2024.109815","DOIUrl":"https://doi.org/10.1016/j.isci.2024.109815","url":null,"abstract":"","PeriodicalId":508122,"journal":{"name":"iScience","volume":"145 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140797306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ganoderma lucidum extract attenuates corticotropin-releasing hormone induced cellular senescence in human hair follicle cells 灵芝提取物可减轻促肾上腺皮质激素释放激素诱导的人毛囊细胞衰老
Pub Date : 2024-04-01 DOI: 10.1016/j.isci.2024.109675
Sunhyoung Lee, So Young Kim, Seunghee Lee, Sunhyae Jang, Sungjoo Tommy Hwang, Youngji Kwon, Jaehwan Choi, Ohsang Kwon
{"title":"Ganoderma lucidum extract attenuates corticotropin-releasing hormone induced cellular senescence in human hair follicle cells","authors":"Sunhyoung Lee, So Young Kim, Seunghee Lee, Sunhyae Jang, Sungjoo Tommy Hwang, Youngji Kwon, Jaehwan Choi, Ohsang Kwon","doi":"10.1016/j.isci.2024.109675","DOIUrl":"https://doi.org/10.1016/j.isci.2024.109675","url":null,"abstract":"","PeriodicalId":508122,"journal":{"name":"iScience","volume":"135 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140783691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Zanubrutinib delays selinexor resistance evolution in biopsy sample-derived primary central nervous system lymphoma models 扎鲁替尼可延缓活检样本衍生的原发性中枢神经系统淋巴瘤模型的西利奈德耐药性演变
Pub Date : 2024-04-01 DOI: 10.1016/j.isci.2024.109799
Xiaohong Zheng, Can Wang, Feng Chen, Shenglan Li, Hua Zhang, Gehong Dong, Shoubo Yang, Xun Kang, Zhuang Kang, Chunlei Han, Shuo Yin, Wenbin Li
{"title":"Zanubrutinib delays selinexor resistance evolution in biopsy sample-derived primary central nervous system lymphoma models","authors":"Xiaohong Zheng, Can Wang, Feng Chen, Shenglan Li, Hua Zhang, Gehong Dong, Shoubo Yang, Xun Kang, Zhuang Kang, Chunlei Han, Shuo Yin, Wenbin Li","doi":"10.1016/j.isci.2024.109799","DOIUrl":"https://doi.org/10.1016/j.isci.2024.109799","url":null,"abstract":"","PeriodicalId":508122,"journal":{"name":"iScience","volume":"59 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140786602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Drug–target interaction prediction using knowledge graph embedding 利用知识图谱嵌入进行药物-靶点相互作用预测
Pub Date : 2024-03-01 DOI: 10.1016/j.isci.2024.109393
Nan Li, Zhihao Yang, Jian Wang, Hongfei Lin
{"title":"Drug–target interaction prediction using knowledge graph embedding","authors":"Nan Li, Zhihao Yang, Jian Wang, Hongfei Lin","doi":"10.1016/j.isci.2024.109393","DOIUrl":"https://doi.org/10.1016/j.isci.2024.109393","url":null,"abstract":"","PeriodicalId":508122,"journal":{"name":"iScience","volume":"95 22","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140086722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A LTB4/CD11b self-amplifying loop drives pyogranuloma formation in Chronic Granulomatous Disease LTB4/CD11b自扩增环路驱动慢性肉芽肿病中脓肿的形成
Pub Date : 2024-03-01 DOI: 10.1016/j.isci.2024.109589
Kelsey C. Haist, Sophie L Gibbings, Jordan Jacobelli, Kara J. Mould, Peter M. Henson, D. Bratton
{"title":"A LTB4/CD11b self-amplifying loop drives pyogranuloma formation in Chronic Granulomatous Disease","authors":"Kelsey C. Haist, Sophie L Gibbings, Jordan Jacobelli, Kara J. Mould, Peter M. Henson, D. Bratton","doi":"10.1016/j.isci.2024.109589","DOIUrl":"https://doi.org/10.1016/j.isci.2024.109589","url":null,"abstract":"","PeriodicalId":508122,"journal":{"name":"iScience","volume":"216 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140403025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The single D380 amino acid substitution increases pneumolysin cytotoxicity towards neuronal cells 单个 D380 氨基酸置换可增加肺溶蛋白对神经细胞的细胞毒性
Pub Date : 2024-03-01 DOI: 10.1016/j.isci.2024.109583
Simona Serra, Vittorio Iannotti, Margherita Ferrante, Miguel Tofiño-Vian, Joseph Baxendale, Gilad Silberberg, Thomas P. Kohler, Sven Hammerschmidt, Andrew T. Ulijasz, Federico Iovino
{"title":"The single D380 amino acid substitution increases pneumolysin cytotoxicity towards neuronal cells","authors":"Simona Serra, Vittorio Iannotti, Margherita Ferrante, Miguel Tofiño-Vian, Joseph Baxendale, Gilad Silberberg, Thomas P. Kohler, Sven Hammerschmidt, Andrew T. Ulijasz, Federico Iovino","doi":"10.1016/j.isci.2024.109583","DOIUrl":"https://doi.org/10.1016/j.isci.2024.109583","url":null,"abstract":"","PeriodicalId":508122,"journal":{"name":"iScience","volume":"156 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140403277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Infrastructure Adequacy for Electricity Trading in East Africa 东非电力交易基础设施的充足性
Pub Date : 2024-03-01 DOI: 10.1016/j.isci.2024.109554
Muhumuza Ezra Rubanda, Livingstone Senyonga, Mohammed Ngoma, M. Adaramola
{"title":"Infrastructure Adequacy for Electricity Trading in East Africa","authors":"Muhumuza Ezra Rubanda, Livingstone Senyonga, Mohammed Ngoma, M. Adaramola","doi":"10.1016/j.isci.2024.109554","DOIUrl":"https://doi.org/10.1016/j.isci.2024.109554","url":null,"abstract":"","PeriodicalId":508122,"journal":{"name":"iScience","volume":"227 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140275623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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