Pub Date : 2023-08-31DOI: 10.20885/jkki.vol14.iss2.art5
H. Nisa, Putri Kurniawati, Rifka Qatrunnida, Dadang Mulyono
Background: Evidence indicates that COVID-19 vaccines are effective at helping to prevent serious infection and risks of hospitalization due to COVID-19. Seven types of vaccines have been used in Indonesia. Adverse events following immunization (AEFI) may occur after the COVID-19 vaccination. Objective: This study aimed to determine factors associated with AEFI of the COVID-19 vaccination.Methods: This cross-sectional study included 160 respondents who had been vaccinated against COVID-19. Data were collected by using google form distributed through social media from October 12-20, 2021. Multivariate analysis was performed by using a logistic regression test.Result: The incidence of AEFI of the COVID-19 vaccination was 69.4%, and the AEFI symptoms were lower in the second dose of COVID-19 vaccine than the first dose. Poor dietary habits were associated with higher risks of the AEFI (OR=2.34 CI 95% 1.14-4.80). The second vaccine dose was related to decreased risks of the AEFI (OR=0.35 CI 95% 0.13-0.92).Conclusion: The incidence of AEFI of the COVID-19 vaccination was quite high, and the common AEFI was systemic symptoms. Dietary habits and vaccine doses were associated with the AEFI of the COVID-19 vaccination. These findings suggest that poor dietary habits may increase the risks of the AEFI, and decreased risks of the AEFI may be experienced in the second dose of COVID-19 vaccine. Further studies are warranted to explore the effects of both doses of COVID-19 vaccines on the AEFI.
{"title":"Factors associated with adverse events following immunization of COVID-19 vaccination","authors":"H. Nisa, Putri Kurniawati, Rifka Qatrunnida, Dadang Mulyono","doi":"10.20885/jkki.vol14.iss2.art5","DOIUrl":"https://doi.org/10.20885/jkki.vol14.iss2.art5","url":null,"abstract":"Background: Evidence indicates that COVID-19 vaccines are effective at helping to prevent serious infection and risks of hospitalization due to COVID-19. Seven types of vaccines have been used in Indonesia. Adverse events following immunization (AEFI) may occur after the COVID-19 vaccination. Objective: This study aimed to determine factors associated with AEFI of the COVID-19 vaccination.Methods: This cross-sectional study included 160 respondents who had been vaccinated against COVID-19. Data were collected by using google form distributed through social media from October 12-20, 2021. Multivariate analysis was performed by using a logistic regression test.Result: The incidence of AEFI of the COVID-19 vaccination was 69.4%, and the AEFI symptoms were lower in the second dose of COVID-19 vaccine than the first dose. Poor dietary habits were associated with higher risks of the AEFI (OR=2.34 CI 95% 1.14-4.80). The second vaccine dose was related to decreased risks of the AEFI (OR=0.35 CI 95% 0.13-0.92).Conclusion: The incidence of AEFI of the COVID-19 vaccination was quite high, and the common AEFI was systemic symptoms. Dietary habits and vaccine doses were associated with the AEFI of the COVID-19 vaccination. These findings suggest that poor dietary habits may increase the risks of the AEFI, and decreased risks of the AEFI may be experienced in the second dose of COVID-19 vaccine. Further studies are warranted to explore the effects of both doses of COVID-19 vaccines on the AEFI.","PeriodicalId":508182,"journal":{"name":"Jurnal Kedokteran dan Kesehatan Indonesia","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139347253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-04-30DOI: 10.20885/jkki.vol11.iss1.art7
Clara Elitha, Pusparini Pusparini
Background: Uses of HbA1c compared with glycated albumin as an indicator of glycemic control for hemodialysis patients(HD) needs to be evaluated. HbA1c has some limitations when used for HD because its results can falsely low or falsely high. It can be missunderstood if clinicians use HbA1c as glycemic control. Objective: This study aimed to evaluate correlation between HbA1c and GA in HD patients with Diabetes Mellitus (DM). Methods: This study was a cross sectional study conducted on November 2016 until January 2017. Its samples were obtained from 43 patients in HD with DM, fullfilling inclusion and exclusion criteria, located in a private hospital at east Jakarta. The HbA1c was measured by using a turbidimetric inhibition immunoassay method, and the GA was measured by using an enzimatic colorimetric method. In addition, a test of Pearson correlation was used to determine the correlation between HbA1c and GA with a significance of p<0.05. Results: Averages of patients age in this study was 57.16 ± 9.0 years old, including 24 men (55.8%) and 19 women (44.2%). The mean values of HbA1C were 8 ± 2.30%, and the mean values of GA were 30.02 ± 13.3%. The mean duration of the HD was 4.5 ± 1.3 years. The glycemic control based on GA was significantly better than the HbA1c with p = 0.028 (Chi-Square test). Pearson correlation showed that there were a significant correlation between HbA1c and GA with r = 0.759 and p = 0.000. Conclusion: There were a significant correlation between HbA1c with GA in HD patients with DM. Glycemic control based on GA was better than HbA1c.
背景：与糖化白蛋白相比，HbA1c 作为血液透析患者血糖控制指标的用途有待评估。HbA1c 在用于血液透析时有一些局限性，因为其结果可能过低或过高。如果临床医生将 HbA1c 用作血糖控制指标，可能会造成误解。研究目的本研究旨在评估糖尿病 (DM) HD 患者 HbA1c 和 GA 之间的相关性。研究方法本研究是一项横断面研究，于 2016 年 11 月至 2017 年 1 月进行。样本来自雅加达东部一家私立医院的 43 名符合纳入和排除标准的糖尿病 HD 患者。HbA1c 采用比浊抑制免疫测定法测定，GA 采用比色法测定。此外，还使用了皮尔逊相关性检验来确定 HbA1c 和 GA 之间的相关性，显著性为 P<0.05。结果本研究中患者的平均年龄为（57.16±9.0）岁，其中男性 24 人（55.8%），女性 19 人（44.2%）。HbA1C 平均值为 8 ± 2.30%，GA 平均值为 30.02 ± 13.3%。HD 的平均持续时间为 4.5 ± 1.3 年。基于 GA 的血糖控制明显优于 HbA1c，P = 0.028（Chi-Square 检验）。Pearson 相关性显示，HbA1c 和 GA 之间存在显著相关性，r = 0.759，p = 0.000。结论HD 糖尿病患者的 HbA1c 与 GA 之间存在明显相关性。基于 GA 的血糖控制效果优于 HbA1c。
{"title":"Correlation of HbA1c and glycated albumin in hemodialysis patients with diabetes melitus","authors":"Clara Elitha, Pusparini Pusparini","doi":"10.20885/jkki.vol11.iss1.art7","DOIUrl":"https://doi.org/10.20885/jkki.vol11.iss1.art7","url":null,"abstract":"Background: Uses of HbA1c compared with glycated albumin as an indicator of glycemic control for hemodialysis patients(HD) needs to be evaluated. HbA1c has some limitations when used for HD because its results can falsely low or falsely high. It can be missunderstood if clinicians use HbA1c as glycemic control. Objective: This study aimed to evaluate correlation between HbA1c and GA in HD patients with Diabetes Mellitus (DM). Methods: This study was a cross sectional study conducted on November 2016 until January 2017. Its samples were obtained from 43 patients in HD with DM, fullfilling inclusion and exclusion criteria, located in a private hospital at east Jakarta. The HbA1c was measured by using a turbidimetric inhibition immunoassay method, and the GA was measured by using an enzimatic colorimetric method. In addition, a test of Pearson correlation was used to determine the correlation between HbA1c and GA with a significance of p<0.05. Results: Averages of patients age in this study was 57.16 ± 9.0 years old, including 24 men (55.8%) and 19 women (44.2%). The mean values of HbA1C were 8 ± 2.30%, and the mean values of GA were 30.02 ± 13.3%. The mean duration of the HD was 4.5 ± 1.3 years. The glycemic control based on GA was significantly better than the HbA1c with p = 0.028 (Chi-Square test). Pearson correlation showed that there were a significant correlation between HbA1c and GA with r = 0.759 and p = 0.000. Conclusion: There were a significant correlation between HbA1c with GA in HD patients with DM. Glycemic control based on GA was better than HbA1c.","PeriodicalId":508182,"journal":{"name":"Jurnal Kedokteran dan Kesehatan Indonesia","volume":"54 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141209175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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