Pub Date : 2024-01-01DOI: 10.4103/pajo.pajo_105_23
Margarida Baptista, C. Bruxelas, Miguel Cordeiro, Marta Guedes
Human T-cell lymphotropic virus type 1 (HTLV-1) is an endemic retrovirus associated with adult T-cell leukemia/lymphoma (ATL), HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM-TSP), and HTLV-1 uveitis (HU). The latter may occur in association with HAM-TSP, more rarely along ATL, or as an isolated manifestation of the viral infection. The authors present a review of the literature on HU, illustrated by a clinical case. A literature search was performed in the MEDLINE database (PubMed) and included surveys completed until 2022. HU prevalence is increasing in nonendemic metropolitan areas due to migration, thus it is becoming an increasingly relevant agent in the differential diagnosis of patients with uveitis.
人类 T 细胞淋巴细胞病毒 1 型(HTLV-1)是一种地方性逆转录病毒,与成人 T 细胞白血病/淋巴瘤(ATL)、HTLV-1 相关骨髓病/热带痉挛性截瘫(HAM-TSP)和 HTLV-1 葡萄膜炎(HU)有关。后者可能与 HAM-TSP 同时出现,但很少与 ATL 同时出现,也可能是病毒感染的一种独立表现。作者通过一个临床病例回顾了有关 HU 的文献。作者在 MEDLINE 数据库(PubMed)中进行了文献检索,并纳入了 2022 年之前完成的调查。由于人口迁移,HU 在非流行的大都市地区的流行率正在上升,因此它正日益成为葡萄膜炎患者鉴别诊断中的重要病原体。
{"title":"Human T-cell lymphotropic virus type 1-related uveitis, review about a case","authors":"Margarida Baptista, C. Bruxelas, Miguel Cordeiro, Marta Guedes","doi":"10.4103/pajo.pajo_105_23","DOIUrl":"https://doi.org/10.4103/pajo.pajo_105_23","url":null,"abstract":"\u0000 Human T-cell lymphotropic virus type 1 (HTLV-1) is an endemic retrovirus associated with adult T-cell leukemia/lymphoma (ATL), HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM-TSP), and HTLV-1 uveitis (HU). The latter may occur in association with HAM-TSP, more rarely along ATL, or as an isolated manifestation of the viral infection. The authors present a review of the literature on HU, illustrated by a clinical case. A literature search was performed in the MEDLINE database (PubMed) and included surveys completed until 2022. HU prevalence is increasing in nonendemic metropolitan areas due to migration, thus it is becoming an increasingly relevant agent in the differential diagnosis of patients with uveitis.","PeriodicalId":508483,"journal":{"name":"The Pan-American Journal of Ophthalmology","volume":"25 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140519686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01DOI: 10.4103/pajo.pajo_107_23
Omer Faruk Yilmaz
{"title":"Comment on: Corneal drug delivery with tattoo technique","authors":"Omer Faruk Yilmaz","doi":"10.4103/pajo.pajo_107_23","DOIUrl":"https://doi.org/10.4103/pajo.pajo_107_23","url":null,"abstract":"","PeriodicalId":508483,"journal":{"name":"The Pan-American Journal of Ophthalmology","volume":"26 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140526936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Our goal is to determine the number of excised chalazion over the last 16 years to see if there is an increase in the last 36 months, particularly during the COVID-19 pandemic. In this retrospective study, 1772 surgically excised cases of chalazion were reviewed. The date range was between 2007 and 2021, and cases were grouped in intervals of 36 months. Information regarding age, sex, and location of the chalazion was also obtained. Of all cases, 54% of the patients (n = 952) were male and 46% (n = 820) were female. The mean age was 46.26 years, ranging from 44.65 to 47.28 in the different groups. There was a relative increase in the number of excised chalazion over the last 36 months. From 2019 to 2021, 506 cases were diagnosed. There were fewer cases in the other groups, as follows: 2016–2018-455 cases; 2013–2015-283 cases; 2010–2012-302 cases; and 2007–2009-226 cases. Regarding location of the excised lesion, 1098 (62%) were in the upper eyelid and 674 (38%) were in the lower eyelid. In the onset of the COVID-19 pandemic, fewer patients sought medical care for nonurgent conditions, such as chalazion. However, our data showed that despite that decrease, there was an increased number in chalazion excisions. Among several possible explanations, we suggest that the use of oral protection, such as masks, could have an impact in the increased incidence of chalazion, particularly the ones that end up being surgically removed.
{"title":"The increasing number of surgically excised chalazion during the COVID-19 pandemic","authors":"Jacqueline Coblentz, Mateus Arruda, Heitor Nogueira, Angela Fajardo, Kubra Ozdemir, MiguelN Burnier","doi":"10.4103/pajo.pajo_42_23","DOIUrl":"https://doi.org/10.4103/pajo.pajo_42_23","url":null,"abstract":"\u0000 \u0000 \u0000 Our goal is to determine the number of excised chalazion over the last 16 years to see if there is an increase in the last 36 months, particularly during the COVID-19 pandemic.\u0000 \u0000 \u0000 \u0000 In this retrospective study, 1772 surgically excised cases of chalazion were reviewed. The date range was between 2007 and 2021, and cases were grouped in intervals of 36 months. Information regarding age, sex, and location of the chalazion was also obtained.\u0000 \u0000 \u0000 \u0000 Of all cases, 54% of the patients (n = 952) were male and 46% (n = 820) were female. The mean age was 46.26 years, ranging from 44.65 to 47.28 in the different groups. There was a relative increase in the number of excised chalazion over the last 36 months. From 2019 to 2021, 506 cases were diagnosed. There were fewer cases in the other groups, as follows: 2016–2018-455 cases; 2013–2015-283 cases; 2010–2012-302 cases; and 2007–2009-226 cases. Regarding location of the excised lesion, 1098 (62%) were in the upper eyelid and 674 (38%) were in the lower eyelid.\u0000 \u0000 \u0000 \u0000 In the onset of the COVID-19 pandemic, fewer patients sought medical care for nonurgent conditions, such as chalazion. However, our data showed that despite that decrease, there was an increased number in chalazion excisions. Among several possible explanations, we suggest that the use of oral protection, such as masks, could have an impact in the increased incidence of chalazion, particularly the ones that end up being surgically removed.\u0000","PeriodicalId":508483,"journal":{"name":"The Pan-American Journal of Ophthalmology","volume":"20 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140524544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. I. Nassrallah, Christina Mastromonaco, Emily Marcotte, Emma Youhnovska, Mohamed Abdouh, M. Burnier
To investigate the effect of blue-light filtering intraocular lenses on drusen formation in postmortem eyes via histopathological analysis. One hundred and ninety-three postmortem pseudophakic eyes (100 with a clear intraocular lenses [cIOL] and 93 with a yellow, yellow intraocular lenses [yIOL]) were obtained from the Lions Gift of Sight eye bank. Sex, age-at-surgery, age-at-death, surgery-to-death time, and clinical history were collected. Eyes were sectioned on their coronal and sagittal axes, and formalin-fixed paraffin-embedded macular cross sections were obtained. Sections were stained with hematoxylin and eosin and scanned with the Zeiss Axio Scan. Z1 scanner. Drusen were classified by type, size or subtype, and quantity. Large, soft drusen were present in 49% (n = 95) of eyes, 9% (n = 17) had cuticular drusen, 16% (n = 30) had hard drusen, and 26% (n = 51) had no drusen. There were significantly more cIOL eyes with large, soft drusen (P < 0.001). There were significantly more yIOL eyes with no drusen (P < 0.0001). No significant differences in the presence of hard or cuticular drusen were found. yIOL eyes had significantly higher mean age-at-surgery (P < 0.001) and mean age-at-death (P < 0.05), while cIOL eyes had a significantly higher mean surgery-to-death time (P < 0.05). Finally, significantly more yIOL eyes had a history of smoking (P < 0.01) and hypertension (P < 0.05), while significantly more cIOL eyes had a history of glaucoma (P < 0.05). Large, soft drusen were significantly less prevalent in yIOL eyes than in cIOL eyes and significantly more yIOL eyes had no drusen. These findings suggest that yIOLs may prevent the incidence and development of age-related macular degeneration after cataract surgery.
{"title":"Drusen classification and quantification in pseudophakic postmortem eyes implanted with or without blue-light filtering intraocular lenses","authors":"E. I. Nassrallah, Christina Mastromonaco, Emily Marcotte, Emma Youhnovska, Mohamed Abdouh, M. Burnier","doi":"10.4103/pajo.pajo_87_23","DOIUrl":"https://doi.org/10.4103/pajo.pajo_87_23","url":null,"abstract":"\u0000 \u0000 \u0000 To investigate the effect of blue-light filtering intraocular lenses on drusen formation in postmortem eyes via histopathological analysis.\u0000 \u0000 \u0000 \u0000 One hundred and ninety-three postmortem pseudophakic eyes (100 with a clear intraocular lenses [cIOL] and 93 with a yellow, yellow intraocular lenses [yIOL]) were obtained from the Lions Gift of Sight eye bank. Sex, age-at-surgery, age-at-death, surgery-to-death time, and clinical history were collected. Eyes were sectioned on their coronal and sagittal axes, and formalin-fixed paraffin-embedded macular cross sections were obtained. Sections were stained with hematoxylin and eosin and scanned with the Zeiss Axio Scan. Z1 scanner. Drusen were classified by type, size or subtype, and quantity.\u0000 \u0000 \u0000 \u0000 Large, soft drusen were present in 49% (n = 95) of eyes, 9% (n = 17) had cuticular drusen, 16% (n = 30) had hard drusen, and 26% (n = 51) had no drusen. There were significantly more cIOL eyes with large, soft drusen (P < 0.001). There were significantly more yIOL eyes with no drusen (P < 0.0001). No significant differences in the presence of hard or cuticular drusen were found. yIOL eyes had significantly higher mean age-at-surgery (P < 0.001) and mean age-at-death (P < 0.05), while cIOL eyes had a significantly higher mean surgery-to-death time (P < 0.05). Finally, significantly more yIOL eyes had a history of smoking (P < 0.01) and hypertension (P < 0.05), while significantly more cIOL eyes had a history of glaucoma (P < 0.05).\u0000 \u0000 \u0000 \u0000 Large, soft drusen were significantly less prevalent in yIOL eyes than in cIOL eyes and significantly more yIOL eyes had no drusen. These findings suggest that yIOLs may prevent the incidence and development of age-related macular degeneration after cataract surgery.\u0000","PeriodicalId":508483,"journal":{"name":"The Pan-American Journal of Ophthalmology","volume":"76 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140524916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nikitha Nataraju, N. Apoorva, K. M. Chandana, B. Rachana
Hypertensive disorder is a major cause of maternal and perinatal mortality and morbidity, with preeclampsia and eclampsia being the most common. Preeclampsia is characterized by endothelial dysfunction and vasospasm of vessels, which can be observed by an ocular fundus examination. The fundus usually develops changes such as hypertensive retinopathy, papilledema, exudative retinal detachment, and vitreous and preretinal hemorrhages. Retinopathy is associated with placental insufficiency and intrauterine growth retardation. Therefore, this study has been undertaken to assess the prevalence of retinal changes in preeclampsia and their association with fetal parameters. To study the fundus changes in preeclampsia. To study the relationship between fundus changes and fetal outcome with respect to various parameters like birth weight, APGAR score, stillbirth, and perinatal death. To study the relationship between fundus changes with respect to proteinuria and serum uric acid. Observational study. One hundred patients presenting to the department of obstetrics and gynecology diagnosed with preeclampsia at a tertiary care center were included in the study. The patient recruited underwent an ocular examination using Snellen’s chart, a pupillary examination, a slit lamp examination, and a dilated fundus examination. The retinopathy was graded according to Keith and Wagner’s classification. The fetal parameters considered were birth weight, APGAR score, stillbirth, and neonatal death. Patients ages ranged from 25 to 30 years old, with an average of 23.28 ± 3.37. Average systolic and diastolic blood pressures were 156.9 ± 17.961 and 104.88 ± 13.58, respectively. All patients had normal anterior segments. Visual acuity was6/6 in most of the patients. Fundus changes were noted in 48% of patients. Based on retinopathy classification, we found 66.7% patients with Grade 1 and 27.1% patients with Grade 2 hypertensive retinopathy. Only 6.3% of patients presented with Grade 3 hypertensive retinopathy. There was a significant association between retinopathy and proteinuria (P = 0.003), serum uric acid (P = 0.002), and the fetal birth weight (P = 0.001). Our findings suggest that progressive fundal changes in preeclampsia indicate worsening of the pathophysiological status of pregnancy-induced hypertension (PIH) and help in management. The degree of hypertensive retinopathy in women with preeclampsia is a valid and reliable prognostic factor that serves as an indirect marker of the severity of PIH and fetal outcome. Fundus examination is a simple, noninvasive, and cost-effective procedure that could be the initial finding in an asymptomatic patient who may require immediate management, which may help in saving the lives of both the mother and the baby. Fundus evaluation is essential for all patients with PIH.
{"title":"Fundoscopic changes in preeclampsia and eclampsia and their association with fetal outcome","authors":"Nikitha Nataraju, N. Apoorva, K. M. Chandana, B. Rachana","doi":"10.4103/pajo.pajo_38_23","DOIUrl":"https://doi.org/10.4103/pajo.pajo_38_23","url":null,"abstract":"\u0000 \u0000 \u0000 Hypertensive disorder is a major cause of maternal and perinatal mortality and morbidity, with preeclampsia and eclampsia being the most common. Preeclampsia is characterized by endothelial dysfunction and vasospasm of vessels, which can be observed by an ocular fundus examination. The fundus usually develops changes such as hypertensive retinopathy, papilledema, exudative retinal detachment, and vitreous and preretinal hemorrhages. Retinopathy is associated with placental insufficiency and intrauterine growth retardation. Therefore, this study has been undertaken to assess the prevalence of retinal changes in preeclampsia and their association with fetal parameters.\u0000 \u0000 \u0000 \u0000 To study the fundus changes in preeclampsia. To study the relationship between fundus changes and fetal outcome with respect to various parameters like birth weight, APGAR score, stillbirth, and perinatal death. To study the relationship between fundus changes with respect to proteinuria and serum uric acid.\u0000 \u0000 \u0000 \u0000 Observational study.\u0000 \u0000 \u0000 \u0000 One hundred patients presenting to the department of obstetrics and gynecology diagnosed with preeclampsia at a tertiary care center were included in the study. The patient recruited underwent an ocular examination using Snellen’s chart, a pupillary examination, a slit lamp examination, and a dilated fundus examination. The retinopathy was graded according to Keith and Wagner’s classification. The fetal parameters considered were birth weight, APGAR score, stillbirth, and neonatal death.\u0000 \u0000 \u0000 \u0000 Patients ages ranged from 25 to 30 years old, with an average of 23.28 ± 3.37. Average systolic and diastolic blood pressures were 156.9 ± 17.961 and 104.88 ± 13.58, respectively. All patients had normal anterior segments. Visual acuity was6/6 in most of the patients. Fundus changes were noted in 48% of patients. Based on retinopathy classification, we found 66.7% patients with Grade 1 and 27.1% patients with Grade 2 hypertensive retinopathy. Only 6.3% of patients presented with Grade 3 hypertensive retinopathy. There was a significant association between retinopathy and proteinuria (P = 0.003), serum uric acid (P = 0.002), and the fetal birth weight (P = 0.001).\u0000 \u0000 \u0000 \u0000 Our findings suggest that progressive fundal changes in preeclampsia indicate worsening of the pathophysiological status of pregnancy-induced hypertension (PIH) and help in management. The degree of hypertensive retinopathy in women with preeclampsia is a valid and reliable prognostic factor that serves as an indirect marker of the severity of PIH and fetal outcome. Fundus examination is a simple, noninvasive, and cost-effective procedure that could be the initial finding in an asymptomatic patient who may require immediate management, which may help in saving the lives of both the mother and the baby. Fundus evaluation is essential for all patients with PIH.\u0000","PeriodicalId":508483,"journal":{"name":"The Pan-American Journal of Ophthalmology","volume":"75 1-2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140516476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rita C Basto, Catarina Francisco, A. Silva, Ana Rita Viana, Renato Correia Barbosa, Sofia Teixeira, Catarina Cunha Ferreira, Carolina Madeira, Rui Carvalho, Carla Teixeira, Paula Tenedório
This is a two-center, case series of three patients with postoperative refractory cystoid macular edema (CME) and disruption of the iris–lens diaphragm, submitted to scleral fixation of fluocinolone acetonide implant. All patients achieved successful CME reduction with visual acuity improvement. The surgical procedure was uneventful in all cases; however, one patient developed hypotony with leakage from the scleral tunnel, which was successfully resolved with reinforcement of the suture and injection of viscoelastics in the anterior chamber. No case of implant migration was observed and patients did not report any visual field disturbances. Our results emphasize this surgical technique as an effective and safe procedure for patients with persistent CME and disruption of the iris–lens diaphragm.
{"title":"Fluocinolone acetonide implant scleral fixation for cystoid macular edema in eyes with iris–lens diaphragm disruption","authors":"Rita C Basto, Catarina Francisco, A. Silva, Ana Rita Viana, Renato Correia Barbosa, Sofia Teixeira, Catarina Cunha Ferreira, Carolina Madeira, Rui Carvalho, Carla Teixeira, Paula Tenedório","doi":"10.4103/pajo.pajo_26_23","DOIUrl":"https://doi.org/10.4103/pajo.pajo_26_23","url":null,"abstract":"\u0000 This is a two-center, case series of three patients with postoperative refractory cystoid macular edema (CME) and disruption of the iris–lens diaphragm, submitted to scleral fixation of fluocinolone acetonide implant. All patients achieved successful CME reduction with visual acuity improvement. The surgical procedure was uneventful in all cases; however, one patient developed hypotony with leakage from the scleral tunnel, which was successfully resolved with reinforcement of the suture and injection of viscoelastics in the anterior chamber. No case of implant migration was observed and patients did not report any visual field disturbances. Our results emphasize this surgical technique as an effective and safe procedure for patients with persistent CME and disruption of the iris–lens diaphragm.","PeriodicalId":508483,"journal":{"name":"The Pan-American Journal of Ophthalmology","volume":"112 3-4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140523347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01DOI: 10.4103/pajo.pajo_109_23
Edgar Lozano-Cruz
{"title":"Commentary: “To study the role of hematological biomarkers in type 2 diabetes patients with diabetic retinopathy”","authors":"Edgar Lozano-Cruz","doi":"10.4103/pajo.pajo_109_23","DOIUrl":"https://doi.org/10.4103/pajo.pajo_109_23","url":null,"abstract":"","PeriodicalId":508483,"journal":{"name":"The Pan-American Journal of Ophthalmology","volume":"50 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140519192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daniele Oliveira, Adriana Ribeiro, Sílvia Diniz, Helena Cabral-Marques, Diogo Sousa-Martins
Basal cell carcinoma (BCC), the most common malignant tumor, accounts for 85%–95% of cases of eyelid malignant tumors. Demographic factors such as age, gender, tumor location, and subtype play a crucial role in epidemiological knowledge. We investigated eyelid BCC diagnosis and treatment at the Department of Ophthalmology in Centro Hospitalar de Setúbal (CHS). A retrospective study was conducted on patient cases with suspected eyelid epithelial tumors who underwent excisional biopsy surgery. The study included data from the CHS database between 2015 and 2021. Data collection and subsequent analysis were based on histopathological results. In our study, were analyzed a total of 47 tumor cases, with 68.1% located on the lower eyelids and 31.9% on the upper eyelids. Among these cases, 25 (53.2%) were classified as benign, while 22 (46.8%) were identified as malignant eyelid tumors. BCCs accounted for 90.9% of all malignant cases, with an average age of 71.7 ± 16.6 years. The nodular subtype was the most prevalent, followed by infiltrative and superficial subtypes. Superficial BCC patients were older than infiltrative BCC patients (median age = 69.5 years vs. 61.5 years). BCC primarily affected the lower eyelids compared to the upper eyelid, and there was a slight female predominance (n = 11). All diagnosed BCCs correlated with sun-exposed regions. Timely intervention is crucial for reducing morbidity. These findings emphasize the need for improved registration and notification systems to enhance the prevention and treatment of eyelid BCCs. Furthermore, despite advancements in ultraviolet-blocking technologies, further development of sunscreen specifically formulated for ocular use remains necessary to reduce the incidence of eyelid tumors.
{"title":"Incidence of malignant eyelid tumors: A 6-year period review (2015–2021)","authors":"Daniele Oliveira, Adriana Ribeiro, Sílvia Diniz, Helena Cabral-Marques, Diogo Sousa-Martins","doi":"10.4103/pajo.pajo_72_23","DOIUrl":"https://doi.org/10.4103/pajo.pajo_72_23","url":null,"abstract":"\u0000 \u0000 \u0000 Basal cell carcinoma (BCC), the most common malignant tumor, accounts for 85%–95% of cases of eyelid malignant tumors. Demographic factors such as age, gender, tumor location, and subtype play a crucial role in epidemiological knowledge. We investigated eyelid BCC diagnosis and treatment at the Department of Ophthalmology in Centro Hospitalar de Setúbal (CHS).\u0000 \u0000 \u0000 \u0000 A retrospective study was conducted on patient cases with suspected eyelid epithelial tumors who underwent excisional biopsy surgery. The study included data from the CHS database between 2015 and 2021. Data collection and subsequent analysis were based on histopathological results.\u0000 \u0000 \u0000 \u0000 In our study, were analyzed a total of 47 tumor cases, with 68.1% located on the lower eyelids and 31.9% on the upper eyelids. Among these cases, 25 (53.2%) were classified as benign, while 22 (46.8%) were identified as malignant eyelid tumors. BCCs accounted for 90.9% of all malignant cases, with an average age of 71.7 ± 16.6 years. The nodular subtype was the most prevalent, followed by infiltrative and superficial subtypes. Superficial BCC patients were older than infiltrative BCC patients (median age = 69.5 years vs. 61.5 years). BCC primarily affected the lower eyelids compared to the upper eyelid, and there was a slight female predominance (n = 11). All diagnosed BCCs correlated with sun-exposed regions.\u0000 \u0000 \u0000 \u0000 Timely intervention is crucial for reducing morbidity. These findings emphasize the need for improved registration and notification systems to enhance the prevention and treatment of eyelid BCCs. Furthermore, despite advancements in ultraviolet-blocking technologies, further development of sunscreen specifically formulated for ocular use remains necessary to reduce the incidence of eyelid tumors.\u0000","PeriodicalId":508483,"journal":{"name":"The Pan-American Journal of Ophthalmology","volume":"188 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140521359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daniela Chacón-Zambrano, Jaime Andrés Suárez-Garavito, José Leonardo Ramírez Casas, Shirley M. Rosenstiehl, Matilde Mora
Femtosecond laser devices have been praised for their precision in corneal surgery; however, their performance in endothelial corneal graft surgery is still in development compared to the standard microkeratome technique. The purpose of this study is to describe the anatomical and functional differences in surgical outcomes between microkeratome (mk) and femtosecond laser (fs) assisted Descemet stripping automated endothelial keratoplasty (DSAEK). This is an analytic, observational, pilot study of patients who underwent mk-DSAEK or fs-DSAEK. The data were obtained from the clinical records and the institutional transplant registry with a focus on graft measurements, survival, transparency, visual acuity and was further analyzed. A total of 37 participants were included in the study with 70.3% (n = 26) of them being female and 29.7% of them being male (n = 11). Of the 37 eyes, 23 (62.2%) of them underwent mk-DSAEK and 14 (37.8%) of them underwent fs-DSAEK. Optimized femtosecond laser parameters are reported. There was a statistically significant difference in donor graft thickness which was thinner in the fs-DSAEK group with a median of 110 mm interquartile range (IQR) (102.25–117.5) versus a median of 233 mm IQR (219–243.75) P = 0.00 in the mk-DSAEK group. There were no significant differences for other variables between techniques. Fs-DSAEK allowed significantly thinner graft obtention in comparison to mk-DSAEK; however, there were no significant differences between mk-DSAEK and fs-DSAEK in terms of transparency, graft survival, or visual acuity.
{"title":"Anatomical and functional results of femtosecond laser-assisted descemet stripping automated endothelial keratoplasty compared to microkeratome-assisted descemet stripping automated endothelial keratoplasty","authors":"Daniela Chacón-Zambrano, Jaime Andrés Suárez-Garavito, José Leonardo Ramírez Casas, Shirley M. Rosenstiehl, Matilde Mora","doi":"10.4103/pajo.pajo_98_23","DOIUrl":"https://doi.org/10.4103/pajo.pajo_98_23","url":null,"abstract":"\u0000 \u0000 \u0000 Femtosecond laser devices have been praised for their precision in corneal surgery; however, their performance in endothelial corneal graft surgery is still in development compared to the standard microkeratome technique. The purpose of this study is to describe the anatomical and functional differences in surgical outcomes between microkeratome (mk) and femtosecond laser (fs) assisted Descemet stripping automated endothelial keratoplasty (DSAEK).\u0000 \u0000 \u0000 \u0000 This is an analytic, observational, pilot study of patients who underwent mk-DSAEK or fs-DSAEK. The data were obtained from the clinical records and the institutional transplant registry with a focus on graft measurements, survival, transparency, visual acuity and was further analyzed.\u0000 \u0000 \u0000 \u0000 A total of 37 participants were included in the study with 70.3% (n = 26) of them being female and 29.7% of them being male (n = 11). Of the 37 eyes, 23 (62.2%) of them underwent mk-DSAEK and 14 (37.8%) of them underwent fs-DSAEK. Optimized femtosecond laser parameters are reported. There was a statistically significant difference in donor graft thickness which was thinner in the fs-DSAEK group with a median of 110 mm interquartile range (IQR) (102.25–117.5) versus a median of 233 mm IQR (219–243.75) P = 0.00 in the mk-DSAEK group. There were no significant differences for other variables between techniques.\u0000 \u0000 \u0000 \u0000 Fs-DSAEK allowed significantly thinner graft obtention in comparison to mk-DSAEK; however, there were no significant differences between mk-DSAEK and fs-DSAEK in terms of transparency, graft survival, or visual acuity.\u0000","PeriodicalId":508483,"journal":{"name":"The Pan-American Journal of Ophthalmology","volume":"23 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140521884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}