Pub Date : 2024-03-15DOI: 10.12775/jehs.2024.64.001
Bogusława Ryś, Aneta Gruszczyk
The presented work focuses on the description of issues related to ischemic stroke and the presentation of the patient's care process after this incident. The first part is a clinical description of the disease, and the second part is a case report of a patient after an ischemic stroke staying in a neurological ward. The work also includes a description of the course of hospitalization, nursing problems, nursing interventions undertaken and evaluations of nursing activities.
{"title":"Nursing care of a 69-year-old patient after a stroke staying in the neurological ward","authors":"Bogusława Ryś, Aneta Gruszczyk","doi":"10.12775/jehs.2024.64.001","DOIUrl":"https://doi.org/10.12775/jehs.2024.64.001","url":null,"abstract":"The presented work focuses on the description of issues related to ischemic stroke and the presentation of the patient's care process after this incident. The first part is a clinical description of the disease, and the second part is a case report of a patient after an ischemic stroke staying in a neurological ward. \u0000The work also includes a description of the course of hospitalization, nursing problems, nursing interventions undertaken and evaluations of nursing activities.","PeriodicalId":509157,"journal":{"name":"Journal of Education, Health and Sport","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140238795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-23DOI: 10.12775/jehs.2024.63.005
Nataliia Momot, S. Vorotyntsev
Intra-abdominal hypertension is an often underestimated risk factor for acute kidney injury (AKI). But the values of intra-abdominal pressure (IAP) and abdominal perfusion pressure (APP), which are critical for the development of AKI in elderly patients after urgent abdominal surgery, are still not defined.Objective. To evaluate the relationship between IAP and APP and the development of acute kidney injury in geriatric patients after emergency abdominal surgery.Materials and methods. A prospective single-center study included 66 patients older than 60 years who underwent surgery for peritonitis and were transferred to the intensive care unit. Statistical processing was performed using the program "STATISTICA for Windows 13" (StatSoftInc., No. JPZ804I382130ARCN10-J).Results. Among the examined patients, 48 developed AKI (73%). The average values of IAP in patients with AKI and without AKI were 10.4 (7.4, 13.3) mm Hg and 6.7 (4.4; 9.6) mm Hg respectively (p<0.0001). APP in patients with AKI, respectively, was significantly lower (72 (61.5, 83.7)) than in patients without AKI (85.6 (74.5, 94.4; p<0.0001)). According to the results of logistic regression analysis, a relationship between high IAP values and the development of AKI was revealed: the odds ratio (OR) was 3.4 with the value of the criterion x2=32.4 (р<0.0001). The odds ratio between the reduction of APP and the development of AKI was 2.3 with the value of the criterion x2=13.4 (p=0.0002).ROC analysis showed that IAP>10.4 mm Hg. is the threshold level for the development of AKI with a sensitivity of 46% and a specificity of 90.5%, with an area under the AUC curve of 0.74 (p<0.001). APP<79.12 mm Hg is critical for the development of AKI, with a sensitivity of 66.4% and a specificity of 70%, with an area under the AUC curve of 0.68 (p<0.001).Conclusions. High values of IAP and reduction of APP are associated with the occurrence of acute kidney injury in elderly patients after emergency abdominal surgery.
腹腔内高血压是急性肾损伤（AKI）的一个经常被低估的危险因素。但腹内压（IAP）和腹腔灌注压（APP）的值对急诊腹部手术后老年患者发生急性肾损伤至关重要，但目前仍未确定。评估 IAP 和 APP 与急诊腹部手术后老年患者发生急性肾损伤的关系。一项前瞻性单中心研究纳入了 66 名因腹膜炎接受手术并转入重症监护室的 60 岁以上患者。使用 "STATISTICA for Windows 13 "程序（StatSoftInc.，编号：JPZ804I382130ARCN10-J）进行统计处理。在接受检查的患者中，48 例（73%）发生了 AKI。有 AKI 和无 AKI 患者的 IAP 平均值分别为 10.4 (7.4, 13.3) mm Hg 和 6.7 (4.4; 9.6) mm Hg（p10.4 mm Hg. 是发生 AKI 的临界值，灵敏度为 46%，特异度为 90.5%，AUC 曲线下面积为 0.74（p<0.001）。APP<79.12毫米汞柱是发生AKI的关键，其敏感性为66.4%，特异性为70%，AUC曲线下面积为0.68（P<0.001）。结论：IAP的高值和APP的降低与急诊腹部手术后老年患者急性肾损伤的发生有关。
{"title":"Intra-abdominal hypertension as a risk factor for acute kidney injury in geriatric patients after emergency abdominal surgery","authors":"Nataliia Momot, S. Vorotyntsev","doi":"10.12775/jehs.2024.63.005","DOIUrl":"https://doi.org/10.12775/jehs.2024.63.005","url":null,"abstract":"Intra-abdominal hypertension is an often underestimated risk factor for acute kidney injury (AKI). But the values of intra-abdominal pressure (IAP) and abdominal perfusion pressure (APP), which are critical for the development of AKI in elderly patients after urgent abdominal surgery, are still not defined.Objective. To evaluate the relationship between IAP and APP and the development of acute kidney injury in geriatric patients after emergency abdominal surgery.Materials and methods. A prospective single-center study included 66 patients older than 60 years who underwent surgery for peritonitis and were transferred to the intensive care unit. Statistical processing was performed using the program \"STATISTICA for Windows 13\" (StatSoftInc., No. JPZ804I382130ARCN10-J).Results. Among the examined patients, 48 developed AKI (73%). The average values of IAP in patients with AKI and without AKI were 10.4 (7.4, 13.3) mm Hg and 6.7 (4.4; 9.6) mm Hg respectively (p<0.0001). APP in patients with AKI, respectively, was significantly lower (72 (61.5, 83.7)) than in patients without AKI (85.6 (74.5, 94.4; p<0.0001)). According to the results of logistic regression analysis, a relationship between high IAP values and the development of AKI was revealed: the odds ratio (OR) was 3.4 with the value of the criterion x2=32.4 (р<0.0001). The odds ratio between the reduction of APP and the development of AKI was 2.3 with the value of the criterion x2=13.4 (p=0.0002).ROC analysis showed that IAP>10.4 mm Hg. is the threshold level for the development of AKI with a sensitivity of 46% and a specificity of 90.5%, with an area under the AUC curve of 0.74 (p<0.001). APP<79.12 mm Hg is critical for the development of AKI, with a sensitivity of 66.4% and a specificity of 70%, with an area under the AUC curve of 0.68 (p<0.001).Conclusions. High values of IAP and reduction of APP are associated with the occurrence of acute kidney injury in elderly patients after emergency abdominal surgery. \u0000 ","PeriodicalId":509157,"journal":{"name":"Journal of Education, Health and Sport","volume":"26 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139957222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-22DOI: 10.12775/jehs.2024.63.003
Cezary Guzowski, Joanna Murawska, Martyna Michalska, Karolina Winiarek, Aleksandra Czernicka, K. Kędziora–Kornatowska
Introduction: Recent research are focused on natural compounds for preventing cardiovascular diseases, with emphasis on tyrosol and hydroxytyrosol in olive oil. Cardiovascular diseases are linked to risk factors, and adopting a Mediterranean diet rich in these compounds is recognized for reducing risks. Understanding these compounds' actions may inform new strategies for preventing and treating cardiovascular diseases. Aim: The aim of this paper is a systematic review of articles and research regarding the Role of tyrosol and hydroxytyrosol in Cardioprotection Review methods: An systematic review of scientific literature was conducted using the following keywords: Tyrosol, hydroxytyrosol, cardioprotection, cardiovascular diseases, olive oil cardioprotective role. Thirty-four articles published until 2023 were searched and analyzed. Abbreviated description of the state of knowledge: Tyrosol and hydroxytyrosol, prominent in olive oil, are studied for their potential cardioprotective properties. Linked to a Mediterranean diet, these compounds show promise in reducing cardiovascular disease risk. They counter oxidative stress, improve lipid profiles, and modulate inflammatory processes. Clinical studies suggest their positive impact, with tyrosol also explored as a potential anticoagulant. Ongoing research aims to uncover optimal doses and mechanisms, highlighting their significance in cardiovascular health. Conclusions: Tyrosol and hydroxytyrosol, found in olive oil, show promise in cardioprotection by combating oxidative stress, improving lipid profiles, and modulating inflammation. Clinical studies suggest their positive impact on cardiovascular health. Tyrosol has potential as a anticoagulant and exhibits antioxidant effects. These compounds present a compelling avenue for future therapeutic interventions, with emphasis on understanding mechanisms and optimizing supplementation.
{"title":"Tyrosol and Hydroxytyrosol: Their Role in Cardioprotection","authors":"Cezary Guzowski, Joanna Murawska, Martyna Michalska, Karolina Winiarek, Aleksandra Czernicka, K. Kędziora–Kornatowska","doi":"10.12775/jehs.2024.63.003","DOIUrl":"https://doi.org/10.12775/jehs.2024.63.003","url":null,"abstract":"Introduction: Recent research are focused on natural compounds for preventing cardiovascular diseases, with emphasis on tyrosol and hydroxytyrosol in olive oil. Cardiovascular diseases are linked to risk factors, and adopting a Mediterranean diet rich in these compounds is recognized for reducing risks. Understanding these compounds' actions may inform new strategies for preventing and treating cardiovascular diseases. \u0000Aim: The aim of this paper is a systematic review of articles and research regarding the Role of tyrosol and hydroxytyrosol in Cardioprotection \u0000Review methods: An systematic review of scientific literature was conducted using the following keywords: Tyrosol, hydroxytyrosol, cardioprotection, cardiovascular diseases, olive oil cardioprotective role. Thirty-four articles published until 2023 were searched and analyzed. \u0000Abbreviated description of the state of knowledge: Tyrosol and hydroxytyrosol, prominent in olive oil, are studied for their potential cardioprotective properties. Linked to a Mediterranean diet, these compounds show promise in reducing cardiovascular disease risk. They counter oxidative stress, improve lipid profiles, and modulate inflammatory processes. Clinical studies suggest their positive impact, with tyrosol also explored as a potential anticoagulant. Ongoing research aims to uncover optimal doses and mechanisms, highlighting their significance in cardiovascular health. \u0000Conclusions: Tyrosol and hydroxytyrosol, found in olive oil, show promise in cardioprotection by combating oxidative stress, improving lipid profiles, and modulating inflammation. Clinical studies suggest their positive impact on cardiovascular health. Tyrosol has potential as a anticoagulant and exhibits antioxidant effects. These compounds present a compelling avenue for future therapeutic interventions, with emphasis on understanding mechanisms and optimizing supplementation. ","PeriodicalId":509157,"journal":{"name":"Journal of Education, Health and Sport","volume":"3 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139957772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-19DOI: 10.12775/jehs.2024.61.012
Marta Drabczyk, Kamila Kosyra, Inga Magda, Zuzanna Marczyńska, Antoni Zyśk
Introduction: This review paper aims to discuss the effects of insulin resistance, and its association with various metabolic diseases. Insulin resistance (IR), characterized by diminished tissue responsiveness to physiological insulin levels, is a key component in various metabolic diseases, including type 2 diabetes, cardiovascular disorders (CVDs), obesity, and non-alcoholic fatty liver disease (NAFLD). State of knowledge The consequences of IR are profound; in type 2 diabetes, it hinders glucose utilization by muscle cells, leading to hyperglycemia, muscle damage, and loss of mass and strength. IR also plays a central role in NAFLD, promoting lipid accumulation, hepatic inflammation, fibrosis, and cell death. Materials and methods: A review of chosen literature in the PubMed and Google Scholar databases was conducted, using the following key words: „Insulin resistane”, „Insulin resistance in obesity”, „Obesity”, „Insulin resistance NAFLD”, „Diebetes”, „Insulin resistance CVD” Summary: The consequences of insulin resistance are far-reaching. In the context of type 2 diabetes, it impedes glucose utilization by muscle cells, resulting in hyperglycemia and subsequent muscle cell damage, contributing to loss of mass and strength. Insulin resistance is also a central player in the pathogenesis of non-alcoholic fatty liver disease (NAFLD), fostering lipid accumulation, hepatic inflammation, and, ultimately, fibrosis and cell death. Conclusions: In conclusion, understanding insulin resistance is paramount in addressing the rising prevalence of metabolic diseases globally Controlling insulin resistance emerges as a crucial aspect of managing these metabolic disorders and their complications. Further research into the mechanisms of IR formation and effective intervention strategies is imperative for improving public health outcomes.
导言本综述旨在讨论胰岛素抵抗的影响及其与各种代谢性疾病的关联。胰岛素抵抗（IR）的特点是组织对生理胰岛素水平的反应减弱，是各种代谢性疾病（包括 2 型糖尿病、心血管疾病（CVDs）、肥胖症和非酒精性脂肪肝（NAFLD））的关键组成部分。知识现状 IR 的后果非常严重；在 2 型糖尿病中，IR 会阻碍肌肉细胞对葡萄糖的利用，从而导致高血糖、肌肉损伤、肌肉质量和力量下降。在非酒精性脂肪肝中，IR 也起着核心作用，促进脂质积累、肝脏炎症、纤维化和细胞死亡。材料和方法：使用以下关键词对 PubMed 和 Google Scholar 数据库中选定的文献进行了综述："胰岛素抵抗"、"肥胖症中的胰岛素抵抗"、"肥胖症"、"胰岛素抵抗非酒精性脂肪肝"、"糖尿病"、"胰岛素抵抗心血管疾病" 摘要：胰岛素抵抗的后果影响深远。就 2 型糖尿病而言，胰岛素抵抗阻碍了肌肉细胞对葡萄糖的利用，导致高血糖和随后的肌肉细胞损伤，造成肌肉质量和力量的下降。胰岛素抵抗也是非酒精性脂肪肝（NAFLD）发病机制中的一个核心因素，会促进脂质积累、肝脏炎症，最终导致纤维化和细胞死亡。结论总之，要解决全球代谢性疾病发病率不断上升的问题，了解胰岛素抵抗至关重要。进一步研究胰岛素抵抗的形成机制和有效的干预策略对于改善公共卫生成果至关重要。
{"title":"Insulin resistance and metabolic diseases - a review","authors":"Marta Drabczyk, Kamila Kosyra, Inga Magda, Zuzanna Marczyńska, Antoni Zyśk","doi":"10.12775/jehs.2024.61.012","DOIUrl":"https://doi.org/10.12775/jehs.2024.61.012","url":null,"abstract":"Introduction: This review paper aims to discuss the effects of insulin resistance, and its association with various metabolic diseases. Insulin resistance (IR), characterized by diminished tissue responsiveness to physiological insulin levels, is a key component in various metabolic diseases, including type 2 diabetes, cardiovascular disorders (CVDs), obesity, and non-alcoholic fatty liver disease (NAFLD). \u0000State of knowledge The consequences of IR are profound; in type 2 diabetes, it hinders glucose utilization by muscle cells, leading to hyperglycemia, muscle damage, and loss of mass and strength. IR also plays a central role in NAFLD, promoting lipid accumulation, hepatic inflammation, fibrosis, and cell death. \u0000Materials and methods: A review of chosen literature in the PubMed and Google Scholar databases was conducted, using the following key words: „Insulin resistane”, „Insulin resistance in obesity”, „Obesity”, „Insulin resistance NAFLD”, „Diebetes”, „Insulin resistance CVD” \u0000Summary: The consequences of insulin resistance are far-reaching. In the context of type 2 diabetes, it impedes glucose utilization by muscle cells, resulting in hyperglycemia and subsequent muscle cell damage, contributing to loss of mass and strength. Insulin resistance is also a central player in the pathogenesis of non-alcoholic fatty liver disease (NAFLD), fostering lipid accumulation, hepatic inflammation, and, ultimately, fibrosis and cell death. \u0000Conclusions: In conclusion, understanding insulin resistance is paramount in addressing the rising prevalence of metabolic diseases globally Controlling insulin resistance emerges as a crucial aspect of managing these metabolic disorders and their complications. Further research into the mechanisms of IR formation and effective intervention strategies is imperative for improving public health outcomes.","PeriodicalId":509157,"journal":{"name":"Journal of Education, Health and Sport","volume":"16 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139958509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-18DOI: 10.12775/jehs.2023.48.01.020
V. Kosovsky
The article presents the results of the study of the clinical-anamnestic, clinical-psychopathological and clinical-dynamic features ofthefirst psychotic episode (FPE), taking into account the nosological specificity. It was determined that FPE (F20) is characterized by an early onset and significant duration of the prodrome (more than 3 years), the presence in the clinical picture of a moderate level of negative symptoms (apato-abulous symptoms, manifestations of flattening and rigidity of affect and austic tendencies). FPE (F23) defines the shortest (up to 3 months) prodromal period, the presence in the clinical picture of excitement and anxiety of a high and moderate level, disorganization and physical tension. FPE (F25) is characterized by a rather long prodrome (from 3 months) with manifestations in the form of emotional disorders, the presence in the clinical picture of pronounced symptoms of excitement, depression, anxiety, physical tension and impulsivity, negative symptoms in the form of apatho-abolic manifestations and anhedonia - asociality. According to indicators of the dynamics of the condition of patients with FPE, an unfavorable prognosis for recovery at F20 was determined.
{"title":"Clinical and psychopathological features of the course and outcome of the first psychotic episode","authors":"V. Kosovsky","doi":"10.12775/jehs.2023.48.01.020","DOIUrl":"https://doi.org/10.12775/jehs.2023.48.01.020","url":null,"abstract":"The article presents the results of the study of the clinical-anamnestic, clinical-psychopathological and clinical-dynamic features ofthefirst psychotic episode (FPE), taking into account the nosological specificity. It was determined that FPE (F20) is characterized by an early onset and significant duration of the prodrome (more than 3 years), the presence in the clinical picture of a moderate level of negative symptoms (apato-abulous symptoms, manifestations of flattening and rigidity of affect and austic tendencies). FPE (F23) defines the shortest (up to 3 months) prodromal period, the presence in the clinical picture of excitement and anxiety of a high and moderate level, disorganization and physical tension. FPE (F25) is characterized by a rather long prodrome (from 3 months) with manifestations in the form of emotional disorders, the presence in the clinical picture of pronounced symptoms of excitement, depression, anxiety, physical tension and impulsivity, negative symptoms in the form of apatho-abolic manifestations and anhedonia - asociality. According to indicators of the dynamics of the condition of patients with FPE, an unfavorable prognosis for recovery at F20 was determined.","PeriodicalId":509157,"journal":{"name":"Journal of Education, Health and Sport","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139959019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-17DOI: 10.12775/jehs.2024.61.008
Michał Razik, Piotr Bator, Patrycja Rozwadowska, Jan Ramian, Jakub Rybak, Barbara Magiera, Karol Magiera, Wiktor Razik
Introduction and purpose. Preserving fertility is crucial for cancer patients, aligning with advancements in oncology. As survival rates improve, addressing treatment-related late effects gains importance. Many young patients, aware of therapy toxicity, consider future conception chances, impacting treatment decisions. With a trend toward delayed childbirth and a growing population facing unplanned family planning disruptions, the demand for fertility preservation is expected to rise. This paper provides a brief review of available methods for preserving fertility in cancer patients. State of knowledge. Freezing semen in liquid nitrogen vapor is a standard method for preserving reproductive potential in male cancer patients. Shielding during total-body radiation limits testicular volume reduction, indicating less damage to the germinal epithelium. Hormone suppression treatments are not protective in male cancer patients. Oocyte and embryo cryopreservation are considered secure methods before anticancer treatments, with oocyte cryopreservation being preferred for post-pubertal women. Ovarian tissue cryopreservation remains an alternative method without preliminary treatment, suitable when time is insufficient for ovarian stimulation. Ovarian transposition beyond the intended radiation area, performed laparoscopically, can retain ovarian function. GnRH agonist administration before and during chemotherapy aims to minimize the likelihood of premature ovarian insufficiency. Summary. Advancements in fertility preservation for cancer patients, ranging from traditional cryopreservation to innovative methods like ovarian tissue preservation, highlight a commitment to empowering individuals facing cancer diagnoses. Ongoing research expands possibilities, ensuring a diverse range of strategies that offer tangible and hopeful prospects at the intersection of cancer and reproductive health.
{"title":"Fertility Preservation Strategies in Cancer Patients: A Comprehensive Review","authors":"Michał Razik, Piotr Bator, Patrycja Rozwadowska, Jan Ramian, Jakub Rybak, Barbara Magiera, Karol Magiera, Wiktor Razik","doi":"10.12775/jehs.2024.61.008","DOIUrl":"https://doi.org/10.12775/jehs.2024.61.008","url":null,"abstract":"Introduction and purpose. Preserving fertility is crucial for cancer patients, aligning with advancements in oncology. As survival rates improve, addressing treatment-related late effects gains importance. Many young patients, aware of therapy toxicity, consider future conception chances, impacting treatment decisions. With a trend toward delayed childbirth and a growing population facing unplanned family planning disruptions, the demand for fertility preservation is expected to rise. This paper provides a brief review of available methods for preserving fertility in cancer patients.\u0000 \u0000State of knowledge. Freezing semen in liquid nitrogen vapor is a standard method for preserving reproductive potential in male cancer patients. Shielding during total-body radiation limits testicular volume reduction, indicating less damage to the germinal epithelium. Hormone suppression treatments are not protective in male cancer patients. Oocyte and embryo cryopreservation are considered secure methods before anticancer treatments, with oocyte cryopreservation being preferred for post-pubertal women. Ovarian tissue cryopreservation remains an alternative method without preliminary treatment, suitable when time is insufficient for ovarian stimulation. Ovarian transposition beyond the intended radiation area, performed laparoscopically, can retain ovarian function. GnRH agonist administration before and during chemotherapy aims to minimize the likelihood of premature ovarian insufficiency.\u0000 \u0000Summary. Advancements in fertility preservation for cancer patients, ranging from traditional cryopreservation to innovative methods like ovarian tissue preservation, highlight a commitment to empowering individuals facing cancer diagnoses. Ongoing research expands possibilities, ensuring a diverse range of strategies that offer tangible and hopeful prospects at the intersection of cancer and reproductive health.","PeriodicalId":509157,"journal":{"name":"Journal of Education, Health and Sport","volume":"65 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139959888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-17DOI: 10.12775/jehs.2024.61.007
Paweł Smuszkiewicz-Różański, Gabriela Różańska-Smuszkiewicz, Karolina Koszyczarek, Maja Kotowska, Wiktoria Zamirska, Albin Ziemiański, Katarzyna Zięba, Anna Zygmunt
Introduction and purpose:With the development of civilization, the amount of technology enabling food processing increases. Due to the implementation of these procedures, food can gain new properties that will make it more attractive in the eyes of the consumer. The aim of our work is to collect information on the relationship between the consumption of processed and ultra-processed food and the development of various diseases, with particular emphasis on civilization diseases. State of knowledge:Processed food often contains non-nutritive ingredients, for example, artificial food additives, which have a negative impact on health. Numerous studies demonstrate the correlation between the consumption of ultra-processed food and the development of various diseases. Scientific research suggests that ultra-processed foods may lead to addictive behavioral and biological responses through their reinforcing effects. It also influences the development of various conditions, including obesity, type II diabetes, cardiovascular diseases, depression, and anxiety. Furthermore, its components pass through the placenta. Summary:In light of the research discussed, we are convinced that we cannot remain indifferent to the role of ultra-processed food in the pathogenesis of many diseases. Its multidirectional negative effects show that it is worth conducting further research to discover more consequences of its mechanisms. At the same time, consumers should become more aware of food composition data to be able to make conscious choices and countries should strive to change the food policies.
{"title":"How does the consumption of processed food affect the pathogenesis of various diseases? - literature review","authors":"Paweł Smuszkiewicz-Różański, Gabriela Różańska-Smuszkiewicz, Karolina Koszyczarek, Maja Kotowska, Wiktoria Zamirska, Albin Ziemiański, Katarzyna Zięba, Anna Zygmunt","doi":"10.12775/jehs.2024.61.007","DOIUrl":"https://doi.org/10.12775/jehs.2024.61.007","url":null,"abstract":"Introduction and purpose:With the development of civilization, the amount of technology enabling food processing increases. Due to the implementation of these procedures, food can gain new properties that will make it more attractive in the eyes of the consumer. The aim of our work is to collect information on the relationship between the consumption of processed and ultra-processed food and the development of various diseases, with particular emphasis on civilization diseases. \u0000State of knowledge:Processed food often contains non-nutritive ingredients, for example, artificial food additives, which have a negative impact on health. Numerous studies demonstrate the correlation between the consumption of ultra-processed food and the development of various diseases. Scientific research suggests that ultra-processed foods may lead to addictive behavioral and biological responses through their reinforcing effects. It also influences the development of various conditions, including obesity, type II diabetes, cardiovascular diseases, depression, and anxiety. Furthermore, its components pass through the placenta. \u0000Summary:In light of the research discussed, we are convinced that we cannot remain indifferent to the role of ultra-processed food in the pathogenesis of many diseases. Its multidirectional negative effects show that it is worth conducting further research to discover more consequences of its mechanisms. At the same time, consumers should become more aware of food composition data to be able to make conscious choices and countries should strive to change the food policies.","PeriodicalId":509157,"journal":{"name":"Journal of Education, Health and Sport","volume":"90 15","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139959422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-17DOI: 10.12775/jehs.2024.61.009
Iwona Czerwińska Pawluk, Bożena Kowalska, W. Żukow
Introduction: Liver cirrhosis is a disease whose development is influenced by many factors, including those related to lifestyle. The disease causes disturbances in the functioning of not only the liver but also many other organs and systems. During the course of the disease, there are a number of complications that affect the patient's functioning in all areas. Patients with liver cirrhosis require constant and systematic treatment and comprehensive care, including care provided by nursing staff. Purpose of research: Analysis of problems occurring in the care of patients with liver cirrhosis Material and methods: The study included 103 patients with liver cirrhosis, hospitalized from October 10, 2022 to April 10, 2023. in the Observation and Infection Ward for Adults of the SPZOZ in Puławy. The method used in the work was a diagnostic survey, the technique was a survey, and the research tool was an original survey questionnaire developed for the needs of the research. Results: Patients with liver cirrhosis have many problems of a physical nature and related to non-compliance with medical recommendations, which may affect the inhibition of the progression of the disease, the prevention of complications and the improvement of the general condition. Conclusions: Patients with liver cirrhosis have a number of physical problems, the knowledge of which may affect the organization of work of nursing staff, facilitate the identification of problems, help determine the goal of care and plan nursing interventions. Not all respondents followed the specialist's recommendations, including: in the field of pharmacotherapy, dietary recommendations, performing check-ups, reporting for follow-up visits and physical activity. An important element in the care of a patient with liver cirrhosis is patient education and motivation to follow recommendations that are important in stopping the progression of the disease, preventing complications and improving the general condition.
{"title":"Analysis of problems occurring in the care of a patient with liver cirrhosis","authors":"Iwona Czerwińska Pawluk, Bożena Kowalska, W. Żukow","doi":"10.12775/jehs.2024.61.009","DOIUrl":"https://doi.org/10.12775/jehs.2024.61.009","url":null,"abstract":"Introduction: Liver cirrhosis is a disease whose development is influenced by many factors, including those related to lifestyle. The disease causes disturbances in the functioning of not only the liver but also many other organs and systems. During the course of the disease, there are a number of complications that affect the patient's functioning in all areas. Patients with liver cirrhosis require constant and systematic treatment and comprehensive care, including care provided by nursing staff.\u0000Purpose of research: Analysis of problems occurring in the care of patients with liver cirrhosis\u0000Material and methods: The study included 103 patients with liver cirrhosis, hospitalized from October 10, 2022 to April 10, 2023. in the Observation and Infection Ward for Adults of the SPZOZ in Puławy. The method used in the work was a diagnostic survey, the technique was a survey, and the research tool was an original survey questionnaire developed for the needs of the research.\u0000Results: Patients with liver cirrhosis have many problems of a physical nature and related to non-compliance with medical recommendations, which may affect the inhibition of the progression of the disease, the prevention of complications and the improvement of the general condition.\u0000Conclusions:\u0000\u0000Patients with liver cirrhosis have a number of physical problems, the knowledge of which may affect the organization of work of nursing staff, facilitate the identification of problems, help determine the goal of care and plan nursing interventions.\u0000Not all respondents followed the specialist's recommendations, including: in the field of pharmacotherapy, dietary recommendations, performing check-ups, reporting for follow-up visits and physical activity.\u0000An important element in the care of a patient with liver cirrhosis is patient education and motivation to follow recommendations that are important in stopping the progression of the disease, preventing complications and improving the general condition.\u0000","PeriodicalId":509157,"journal":{"name":"Journal of Education, Health and Sport","volume":"79 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139960196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-16DOI: 10.12775/jehs.2024.61.005
Patrycja Rozwadowska, Piotr Bator, Michał Razik, Jan Ramian, Jakub Rybak, Barbara Magiera, Karol Magiera, Wiktor Razik
Introduction and purpose: Berberine is a plant alkaloid that naturally occurs in the fruits of common barberry (Berberis vulgaris). This alkaloid has long been used in natural medicine. It exhibits a range of bioactivities, such as antioxidant, anti-inflammatory, antidiabetic, anti-edema, and antimicrobial actions. Through the promising therapeutic effects of berberine in metabolic syndrome, as well as its impact on carcinogenesis, this compound is beginning to play a significant role in preventive medicine. Recently, particular attention has been paid to the anticancer properties of berberine, which are based on many biochemical pathways, particularly its pro-apoptotic and anti-inflammatory action. The study aimed to review the anticancer mechanisms of berberine and summarize them about individual cancers. State of knowledge: The article reviews the current literature on the anticancer properties of berberine for individual cancers, focusing primarily on its molecular mechanisms of action. In addition, the potential of berberine as a promising candidate forming the basis for drug production and its use in preventive medicine was analyzed. Summary: In summary, many studies have shown that berberine exhibits anticancer activity in many types of cancers, including breast, lung, stomach, liver, colorectal, ovarian, cervical, and prostate cancers. Berberine inhibits the growth of cancer cells, limits metastases, induces apoptosis, stimulates autophagy, and enhances the effectiveness of anticancer drugs. Despite its potential as a promising candidate for drug production, there are currently no approved pure berberine preparations for the treatment of specific ailments. Research on its effectiveness and safety is still ongoing.
{"title":"Anticancer properties of berberine - analysis of the latest reports","authors":"Patrycja Rozwadowska, Piotr Bator, Michał Razik, Jan Ramian, Jakub Rybak, Barbara Magiera, Karol Magiera, Wiktor Razik","doi":"10.12775/jehs.2024.61.005","DOIUrl":"https://doi.org/10.12775/jehs.2024.61.005","url":null,"abstract":" \u0000Introduction and purpose: \u0000Berberine is a plant alkaloid that naturally occurs in the fruits of common barberry (Berberis vulgaris). This alkaloid has long been used in natural medicine. It exhibits a range of bioactivities, such as antioxidant, anti-inflammatory, antidiabetic, anti-edema, and antimicrobial actions. Through the promising therapeutic effects of berberine in metabolic syndrome, as well as its impact on carcinogenesis, this compound is beginning to play a significant role in preventive medicine. Recently, particular attention has been paid to the anticancer properties of berberine, which are based on many biochemical pathways, particularly its pro-apoptotic and anti-inflammatory action. The study aimed to review the anticancer mechanisms of berberine and summarize them about individual cancers.\u0000 \u0000State of knowledge: \u0000The article reviews the current literature on the anticancer properties of berberine for individual cancers, focusing primarily on its molecular mechanisms of action. In addition, the potential of berberine as a promising candidate forming the basis for drug production and its use in preventive medicine was analyzed.\u0000 \u0000Summary: \u0000In summary, many studies have shown that berberine exhibits anticancer activity in many types of cancers, including breast, lung, stomach, liver, colorectal, ovarian, cervical, and prostate cancers. Berberine inhibits the growth of cancer cells, limits metastases, induces apoptosis, stimulates autophagy, and enhances the effectiveness of anticancer drugs. Despite its potential as a promising candidate for drug production, there are currently no approved pure berberine preparations for the treatment of specific ailments. Research on its effectiveness and safety is still ongoing.","PeriodicalId":509157,"journal":{"name":"Journal of Education, Health and Sport","volume":"16 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139960962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-16DOI: 10.12775/jehs.2024.60.015
Anna Gregułą, Bartosz Mazur, Karol Stachyrak, Dawid Mika, Aleksandra Kłos, Kamila Turek, Maciej Lambach, Mateusz Pawlicki, Aleksandra Mazurek, Wiktoria Wilanowska
Introduction Curcumin, the active ingredient in turmeric, is gaining increasing attention due to its potential health benefits, especially in the context of its immunomodulatory and anticancer properties. Aim of the study The aim of this review was to discuss recent findings regarding the impact of curcumin on the immune system and its potential applications in anticancer therapy. Materials and methods The paper was created based on the Pubmed and Scholar database. The literature was reviewed using the keywords: „curcumin”, „immunomodulatory effects”, „cytokines”, „anticancer”, „apoptosis”, „cell proliferation”, „radiosensitizing”. Results Studies have confirmed that curcumin, especially in the form of nanocurcumin, exhibits significant immunomodulatory effects. It reduces the number of Th17 cells, increases Treg cells, and regulates the expression of pro-inflammatory cytokines, which is crucial in controlling autoimmune reactions. Furthermore, it demonstrates anticancer activity by inhibiting the growth of cancer cells, stimulating apoptosis, and enhancing the effectiveness of anticancer therapy. Conclusions Despite promising results, further research on the safety of curcumin therapy, particularly in the long term, is essential. Limitations associated with bioavailability and pharmacokinetics suggest the need for the development of formulations with increased bioavailability to maximize the potential benefits of curcumin in the treatment of various disorders.
{"title":"Turmeric: A Spice Modulating Immune Response and Combatting Cancer – literature overview","authors":"Anna Gregułą, Bartosz Mazur, Karol Stachyrak, Dawid Mika, Aleksandra Kłos, Kamila Turek, Maciej Lambach, Mateusz Pawlicki, Aleksandra Mazurek, Wiktoria Wilanowska","doi":"10.12775/jehs.2024.60.015","DOIUrl":"https://doi.org/10.12775/jehs.2024.60.015","url":null,"abstract":"Introduction \u0000Curcumin, the active ingredient in turmeric, is gaining increasing attention due to its potential health benefits, especially in the context of its immunomodulatory and anticancer properties.\u0000Aim of the study\u0000The aim of this review was to discuss recent findings regarding the impact of curcumin on the immune system and its potential applications in anticancer therapy.\u0000Materials and methods\u0000The paper was created based on the Pubmed and Scholar database. The literature was reviewed using the keywords: „curcumin”, „immunomodulatory effects”, „cytokines”, „anticancer”, „apoptosis”, „cell proliferation”, „radiosensitizing”.\u0000Results\u0000Studies have confirmed that curcumin, especially in the form of nanocurcumin, exhibits significant immunomodulatory effects. It reduces the number of Th17 cells, increases Treg cells, and regulates the expression of pro-inflammatory cytokines, which is crucial in controlling autoimmune reactions. Furthermore, it demonstrates anticancer activity by inhibiting the growth of cancer cells, stimulating apoptosis, and enhancing the effectiveness of anticancer therapy.\u0000Conclusions\u0000Despite promising results, further research on the safety of curcumin therapy, particularly in the long term, is essential. Limitations associated with bioavailability and pharmacokinetics suggest the need for the development of formulations with increased bioavailability to maximize the potential benefits of curcumin in the treatment of various disorders.","PeriodicalId":509157,"journal":{"name":"Journal of Education, Health and Sport","volume":"36 31","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139961727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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