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Localized mRNA translation and protein association 本地化mRNA翻译和蛋白关联
Pub Date : 2014-07-20 DOI: 10.2478/s11534-014-0486-3
V. Zhdanov
Recent direct observations of localization of mRNAs and proteins both in prokaryotic and eukaryotic cells can be related to slowdown of diffusion of these species due to macromolecular crowding and their ability to aggregate and form immobile or slowly mobile complexes. Here, a generic kinetic model describing both these factors is presented and comprehensively analyzed. Although the model is non-linear, an accurate self-consistent analytical solution of the corresponding reaction-diffusion equation has been constructed, the types of localized protein distributions have been explicitly shown, and the predicted kinetic regimes of gene expression have been classified.
最近在原核和真核细胞中直接观察到的mrna和蛋白质的定位可能与这些物种的扩散减缓有关,这是由于大分子拥挤以及它们聚集和形成固定或缓慢移动复合物的能力。本文提出了一个描述这两个因素的通用动力学模型,并对其进行了综合分析。虽然该模型是非线性的,但已经构建了相应的反应-扩散方程的精确自洽解析解,明确显示了局部蛋白质分布的类型,并对预测的基因表达动力学机制进行了分类。
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引用次数: 0
Threshold conditions and bound states for locally periodic delta potentials 局部周期δ势的阈值条件和束缚态
Pub Date : 2014-07-18 DOI: 10.2478/s11534-014-0508-1
Marappan Dharani, B. Sahu, C. Shastry
We present a systematic study of the conditions for the generation of threshold energy eigen states and also the energy spectrum generated by two types of locally periodic delta potentials each having the same strength λV and separation distance parameter a: (a) sum of N attractive potentials and (b) sum of pairs of attractive and repulsive potentials. Using the dimensionless parameter g = λV a in case (a) the values of g = gn, n = 1, 2, …, N at which threshold energy bound state gets generated are shown to be the roots of Nth order polynomial D1(N, g) in g. We present an algebraic recursive procedure to evaluate the polynomial D1(N, g) for any given N. This method obviates the need for the tedious mathematical analysis described in our earlier work to generate D1(N, g). A similar study is presented for case (b). Using the properties of D1(N, g) we establish that in case (a) the critical minimum value of g which guarantees the generation of the maximum possible number of bound states is g = 4. The corresponding result for case (b) is g = 2. A typical set of numerical results showing the pattern of variation of gn as a function of n and several interesting features of the energy spectrum for different values of g and N are also described.
我们系统地研究了产生阈值能量本征态的条件,以及由两种具有相同强度λV和分离距离参数a的局部周期δ势所产生的能谱:(a) N个吸引势和(b)一对吸引和排斥势和。使用无量纲参数g =λV以防(a)的值g = gn, n = 1, 2,…,n的阈值能量束缚态显示生成的根源n阶多项式D1 (n, g)在g。我们提出一个代数递归过程评估多项式D1 (n, g)对于任何给定的n .这个方法可以不再需要我们的早期作品中描述的乏味的数学分析生成D1 (n, g)。类似的研究提出了为例(b)。使用D1的属性(n,G)我们建立了在情形(a)下保证产生最大可能约束态数的G的临界最小值为G = 4。情形(b)的对应结果为g = 2。还描述了一组典型的数值结果,显示了gn作为n的函数的变化模式,以及不同g和n值时能谱的几个有趣特征。
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引用次数: 5
A comparison of the effect of the ellipticity on the small and large solid-core PCF’s characteristics 椭圆度对小、大实心PCF特性影响的比较
Pub Date : 2014-07-18 DOI: 10.2478/s11534-014-0509-0
Halime Demir Inci, S. Ozsoy
In this paper we study small and large solid-core PCFs with elliptical shaped air-holes for the hexagonal lattice, which were constructed by omitting one air-hole (small core) and seven air-holes (large core), respectively, and we compare their characteristics with those with circular holes. We use two types of ellipticity: vertical and horizontal. Birefringence, dispersion, and the numerical apertures of the fundamental modes are analyzed using commercial simulation software. Also, the confinement loss is obtained. The effect of ellipticity on these characteristics is investigated in detail. It is found that the type of ellipticity of the air holes affects the numerical aperture and hence confinement loss significantly, but it has no crucial effect on either the dispersion or the birefringence for the small and large core PCFs.
本文研究了在六边形晶格上分别省去1个空孔(小芯)和7个空孔(大芯)的带椭圆空孔的小、大实心PCFs,并与带圆孔的PCFs进行了比较。我们使用两种类型的椭圆:垂直和水平。利用商业仿真软件对基模的双折射、色散和数值孔径进行了分析。同时也得到了约束损失。详细研究了椭圆度对这些特性的影响。研究发现,空气孔的椭圆型对数值孔径和约束损失有显著影响,但对小芯和大芯PCFs的色散和双折射均无显著影响。
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引用次数: 0
MCNP simulation of the dose distribution in liver cancer treatment for BNC therapy MCNP模拟肝癌治疗中BNC治疗的剂量分布
Pub Date : 2014-07-18 DOI: 10.2478/s11534-014-0507-2
D. Krstić, Z. Jovanović, V. Markovic, D. Nikezic, V. Urošević
The Boron Neutron Capture Therapy (BNCT) is based on selective uptake of boron in tumour tissue compared to the surrounding normal tissue. Infusion of compounds with boron is followed by irradiation with neutrons. Neutron capture on 10B, which gives rise to an alpha particle and recoiled 7Li ion, enables the therapeutic dose to be delivered to tumour tissue while healthy tissue can be spared. Here, therapeutic abilities of BNCT were studied for possible treatment of liver cancer using thermal and epithermal neutron beam. For neutron transport MCNP software was used and doses in organs of interest in ORNL phantom were evaluated. Phantom organs were filled with voxels in order to obtain depth-dose distributions in them. The result suggests that BNCT using an epithermal neutron beam could be applied for liver cancer treatment.
硼中子俘获疗法(BNCT)是基于与周围正常组织相比,肿瘤组织中硼的选择性摄取。将硼注入化合物后,再用中子照射。10B上的中子捕获会产生α粒子和反作用的7Li离子,从而使治疗剂量能够传递到肿瘤组织,而健康组织可以幸免。在这里,研究了BNCT的治疗能力,以研究热中子束和超热中子束治疗肝癌的可能性。使用MCNP软件进行中子输运,并评估ORNL幻象中感兴趣器官的剂量。用体素填充幻体器官,以获得其中的深度-剂量分布。结果表明,利用超热中子束的BNCT可用于肝癌的治疗。
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引用次数: 8
Calibration of the RSS-131 high efficiency ionization chamber for radiation dose monitoring during plasma experiments conducted on plasma focus device 等离子体聚焦装置等离子体实验中辐射剂量监测用RSS-131高效电离室的校准
Pub Date : 2014-07-07 DOI: 10.2478/s11534-014-0506-3
K. Szewczak, S. Jednoróg
Plasma research poses a radiation hazard. Due to the program of deuterium plasma research using the PF-1000 device, it is an intensive source of neutrons (up to 1011 n · pulse−1) with energy of 2,45 MeV and ionizing electromagnetic radiation with a broad energy spectrum. Both types of radiation are mostly emitted in ultra-short pulses (∼100 ns). The aim of this work was to test and calibrate the RSS-131 radiometer for its application in measurements of ultra-short electromagnetic radiation pulses with broad energy spectrum emitted during PF-1000 discharge. In addition, the results of raw measurements performed in the control room are presented.
等离子体研究有辐射危害。由于使用PF-1000装置的氘等离子体研究计划,它是一个能量为2,45 MeV的中子密集源(高达1011 n·脉冲−1)和具有宽能谱的电离电磁辐射。这两种类型的辐射大多以超短脉冲(~ 100纳秒)发射。本工作的目的是对RSS-131辐射计进行测试和校准,使其能够用于测量PF-1000放电过程中发射的具有宽能谱的超短电磁辐射脉冲。此外,还介绍了在控制室进行的原始测量结果。
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引用次数: 5
“Slow” wave of zero-sound in degenerate Fermi gas 简并费米气体中零声的“慢”波
Pub Date : 2014-07-07 DOI: 10.2478/s11534-014-0491-6
Y. Poluektov, V. Savchenko
The dynamic Hartree-Fock theory with point-like interaction is used to calculate the speed of sound and damping factor of a zero-sound wave propagating in a degenerate Fermi gas. This wave propagates slower than Fermi velocity. It is shown, that if the interaction is weak and density is small, then the damping of such a wave can be small. A possibility of discovering such waves in ultracold Fermi gases is discussed.
采用具有点状相互作用的动态Hartree-Fock理论计算了零声波在简并费米气体中的传播速度和阻尼系数。这种波的传播速度比费米速度慢。结果表明,如果相互作用较弱且密度较小,则这种波的阻尼可以很小。讨论了在超冷费米气体中发现这种波的可能性。
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引用次数: 0
Spectral characterization of hydrogen-like atoms confined by oscillating systems 受振荡系统约束的类氢原子的光谱表征
Pub Date : 2014-07-07 DOI: 10.2478/s11534-014-0496-1
F. Iacob
The spectral characterization of Coulomb systems confined by a homogeneous pseudo-Gaussian oscillator is investigated. This is done using the efficient computational method of generating functionals. Also, this method is used for the spectral characterization of homogeneous harmonic oscillator confinement, treated as a particular case of pseudo-Gaussian oscillator confinement. Finally, confinement by an impenetrable sphere of finite radius is considered by studying its conjugate effect along with a harmonic oscillator.
研究了受均匀伪高斯振子约束的库仑系统的谱特性。这是使用生成函数的有效计算方法来完成的。同时,将此方法作为伪高斯振子约束的一个特例,用于均匀谐振子约束的谱表征。最后,通过研究有限半径不可穿透球与谐振子的共轭效应,考虑了有限半径不可穿透球的约束。
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引用次数: 5
Heat transfer in the plastic phases I and II of cyclopentane 环戊烷的塑性I、II相传热
Pub Date : 2014-07-07 DOI: 10.2478/s11534-014-0501-8
V. Konstantinov, V. Sagan, V. P. Revyakin, A. V. Karachevtseva, O. Pursky
Thermal conductivity of solid cyclopentane C5H10 has been measured at isochoric conditions in the plastic phases I and II for samples of different densities. Isochoric thermal conductivity is nearly constant in phase II and increases with temperature in phase I. Such behaviour is attributed to weakening of the translational orientational coupling which, in turn, leads to a decrease of phonon scattering on rotational excitations. The experimental data are described in terms of a modified Debye model of thermal conductivity with allowance for heat transfer by both low-frequency phonons and diffusive modes.
测定了固体环戊烷C5H10在不同密度的塑料相I和II等时条件下的导热系数。等时热导率在相II中几乎是恒定的,而在相i中随着温度的升高而增加。这种行为归因于平移取向耦合的减弱,这反过来又导致旋转激励下声子散射的减少。实验数据是根据修正的德拜导热模型描述的,该模型考虑了低频声子和扩散模式的传热。
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引用次数: 5
Analysis of the fluctuations of a laser beam due to thermal turbulence 热湍流引起激光束波动的分析
Pub Date : 2014-07-01 DOI: 10.2478/s11534-014-0479-2
S. C. Ndlovu, N. Chetty
A laser beam propagating in air and passing through a point diffraction interferometer (PDI) produces stable interferograms that can be used to extract wavefront data such as major atmospheric characteristics: turbulence strength, inner scale and outer scale of the refractive index. These parameters need to be taken into consideration when developing defense laser weapons since they can be affected by thermal fluctuations that are due to the changes in temperature in close proximity to the propagating beam and results in phase shifts that can be used to calculate the temperature which causes wavefront perturbations on a propagating beam.
激光束在空气中传播并通过点衍射干涉仪(PDI)产生稳定的干涉图,可用于提取波前数据,如主要大气特征:湍流强度,折射率的内尺度和外尺度。在开发防御激光武器时需要考虑到这些参数,因为它们可能受到热波动的影响,热波动是由于传播光束附近的温度变化引起的,并导致相移,可用于计算引起传播光束波前扰动的温度。
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引用次数: 4
Deformation effects on isospin mixing and isobar analogue resonance for 74−80Kr isotopes 形变对74−80Kr同位素同位旋混合和等压线模拟共振的影响
Pub Date : 2014-07-01 DOI: 10.2478/s11534-014-0471-x
H. A. Aygör, S. Ünlü, N. Çakmak, C. Selam
Pyatov’s method has been applied to investigate Fermi beta transitions in deformed 74–80Kr isotopes. This self-consistent method, which was used to study the isobar analogue states in the spherical odd-odd nuclei, has to date not been applied for the isobar analogue states in deformed nuclei. The nucleon-nucleon residual interaction has been included so that the broken isospin symmetry in the mean field approximation has been restored and the strength parameter of the effective interaction has been taken out to be a free parameter. The energies and wave functions of the isobaric analogue excitations in 74–80Rb isotopes have been obtained within the framework of the pnQRPA method. The probability of the isospin mixing in the ground states and the centroid energies of the isobar analogue resonance have been presented and the deformation effects on these quantities have been quantified.
Pyatov的方法已经应用于研究变形74-80Kr同位素中的费米β跃迁。这种自洽方法用于研究球形奇-奇核的等压线模拟态,迄今尚未应用于形变核的等压线模拟态。在平均场近似中加入核子-核子剩余相互作用,恢复了同位旋的破缺对称性,并将有效相互作用的强度参数提取为自由参数。在pnQRPA方法的框架内,得到了74-80Rb同位素等压模拟激发的能量和波函数。给出了基态同位旋混合的概率和等压线模拟共振的质心能量,并量化了变形对这些量的影响。
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引用次数: 2
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Central European Journal of Physics
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