Alejandro Hernández-Solis, Andrea Quintana-Martínez, M Inés Quintanar-Ramírez, Pablo Álvarez-Maldonado, Arturo Reding-Bernal
Extrapulmonary tuberculosis is defined as that case of tuberculosis clinically diagnosed and confirmed by bacteriological studies that affects tissues and organs outside the lung parenchyma. Mexico is in third place among Latin American countries in terms of the incidence of pulmonary and extrapulmonary tuberculosis. Culture methods are still the gold standard for the diagnosis of extrapulmonary tuberculosis since they identify the species and susceptibility to drugs.
{"title":"Tuberculosis extrapulmonar: un problema de salud pública.","authors":"Alejandro Hernández-Solis, Andrea Quintana-Martínez, M Inés Quintanar-Ramírez, Pablo Álvarez-Maldonado, Arturo Reding-Bernal","doi":"10.24875/CIRU.21000688","DOIUrl":"https://doi.org/10.24875/CIRU.21000688","url":null,"abstract":"<p><p>Extrapulmonary tuberculosis is defined as that case of tuberculosis clinically diagnosed and confirmed by bacteriological studies that affects tissues and organs outside the lung parenchyma. Mexico is in third place among Latin American countries in terms of the incidence of pulmonary and extrapulmonary tuberculosis. Culture methods are still the gold standard for the diagnosis of extrapulmonary tuberculosis since they identify the species and susceptibility to drugs.</p>","PeriodicalId":50990,"journal":{"name":"Cirugia Y Cirujanos","volume":"91 1","pages":"131-138"},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9297155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jessica P García-Chávez, Mónica M Meléndez-Abanto, Óscar Guerrero-Berger, Humberto Wong-Chavarria, Héctor J Pérez-Cano, Cristina Mendoza-Velásquez
Purpose: To evaluate the stability and the refractive error of the different intraocular lens (IOL) after cataract surgery.
Method: Retrospective, observational and single-center study. Patients diagnosed with cataract and myopia who underwent a phacoemulsification surgery with intraocular lens placement without complications were included. All patients underwent a complete ophthalmological examination, ultrasound biomicroscopy was performed at 2 weeks, 1 and 3 months after surgery. Descriptive statistics were performed using measures of central tendency and comparative analyzes. A value of p < 0.05 was considered significant.
Results: Thirty-one subjects with a diagnosis of axial myopia and senile cataract were included, 20 women (64.5%) and 11 men (35.5%), with a mean age was 62.8 ± 13.14 years. The IOL displacement were not different for the upper, lower, temporal and nasal quadrants; however, we observed a tendency to inclination to the temporal sector (p = 0.054) between the first and third postoperative month. Therefore, the were no significant differences in spherical equivalent between groups postoperatively.
Conclusions: The inclination of the IOL did not change over time after surgery, the changes were similar with the different three types of IOL.
{"title":"Ultrabiomicroscopía ultrasónica y estabilidad de la lente intraocular en pacientes con miopía axial sometidos a cirugía de facoemulsificación.","authors":"Jessica P García-Chávez, Mónica M Meléndez-Abanto, Óscar Guerrero-Berger, Humberto Wong-Chavarria, Héctor J Pérez-Cano, Cristina Mendoza-Velásquez","doi":"10.24875/CIRU.21000720","DOIUrl":"https://doi.org/10.24875/CIRU.21000720","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the stability and the refractive error of the different intraocular lens (IOL) after cataract surgery.</p><p><strong>Method: </strong>Retrospective, observational and single-center study. Patients diagnosed with cataract and myopia who underwent a phacoemulsification surgery with intraocular lens placement without complications were included. All patients underwent a complete ophthalmological examination, ultrasound biomicroscopy was performed at 2 weeks, 1 and 3 months after surgery. Descriptive statistics were performed using measures of central tendency and comparative analyzes. A value of p < 0.05 was considered significant.</p><p><strong>Results: </strong>Thirty-one subjects with a diagnosis of axial myopia and senile cataract were included, 20 women (64.5%) and 11 men (35.5%), with a mean age was 62.8 ± 13.14 years. The IOL displacement were not different for the upper, lower, temporal and nasal quadrants; however, we observed a tendency to inclination to the temporal sector (p = 0.054) between the first and third postoperative month. Therefore, the were no significant differences in spherical equivalent between groups postoperatively.</p><p><strong>Conclusions: </strong>The inclination of the IOL did not change over time after surgery, the changes were similar with the different three types of IOL.</p>","PeriodicalId":50990,"journal":{"name":"Cirugia Y Cirujanos","volume":"91 1","pages":"107-112"},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10750092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Carlos A Hinojosa-Becerril, Javier E Anaya-Ayala, Luis Bobadilla-Rosado, Juan C Arámburo-López, Luis Barragán-Galindo, Rodrigo Lozano-Corona, Adriana Torres-Machorro, Hugo Laparra-Escareno
Objective: To review admissions, interventions and in-hospital mortality associated to Abdominal Aortic Aneurysms (AAA), and to analyze the impact of the introduction of a training program and imaging screening at our institution.
Methods: Retrospective study where hospitalizations, procedures and mortality secondary to AAA were recorded. The national databases (ND) from the Secretariat of Health were utilized from 2010 to 2020. In-hospital lethality was calculated and compared with the experience at the Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán (INCMNSZ). The statistical analysis was completed with the STATA version 17.
Results: According to the ND, 899 (91%) hospital admissions secondary to AAA occurred, while in the INCMNSZ 85 (9%). Most of them belonged to the male gender (68%); 811 (82%) patients underwent open surgical repair, and 173 (18%) to an endovascular exclusion (EVAR), the latter approach was significantly more frequently performed at our institution (p = 0.007). The 30-day hospital mortality was 22.5%; in the ND was 23.9 vs. a 16.4% in the INCMNSZ without significant difference (p = 0.1).
Conclusions: AAA remain unrecognized in our country. The introduction of University programs and imaging screening might impact in the early detection, and to reduce the morbidity and mortality associated to emergency procedures.
{"title":"Efforts for detection of aortic aneurysms and human resources training for the optimization of their treatment.","authors":"Carlos A Hinojosa-Becerril, Javier E Anaya-Ayala, Luis Bobadilla-Rosado, Juan C Arámburo-López, Luis Barragán-Galindo, Rodrigo Lozano-Corona, Adriana Torres-Machorro, Hugo Laparra-Escareno","doi":"10.24875/CIRU.22000300","DOIUrl":"10.24875/CIRU.22000300","url":null,"abstract":"<p><strong>Objective: </strong>To review admissions, interventions and in-hospital mortality associated to Abdominal Aortic Aneurysms (AAA), and to analyze the impact of the introduction of a training program and imaging screening at our institution.</p><p><strong>Methods: </strong>Retrospective study where hospitalizations, procedures and mortality secondary to AAA were recorded. The national databases (ND) from the Secretariat of Health were utilized from 2010 to 2020. In-hospital lethality was calculated and compared with the experience at the Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán (INCMNSZ). The statistical analysis was completed with the STATA version 17.</p><p><strong>Results: </strong>According to the ND, 899 (91%) hospital admissions secondary to AAA occurred, while in the INCMNSZ 85 (9%). Most of them belonged to the male gender (68%); 811 (82%) patients underwent open surgical repair, and 173 (18%) to an endovascular exclusion (EVAR), the latter approach was significantly more frequently performed at our institution (p = 0.007). The 30-day hospital mortality was 22.5%; in the ND was 23.9 vs. a 16.4% in the INCMNSZ without significant difference (p = 0.1).</p><p><strong>Conclusions: </strong>AAA remain unrecognized in our country. The introduction of University programs and imaging screening might impact in the early detection, and to reduce the morbidity and mortality associated to emergency procedures.</p>","PeriodicalId":50990,"journal":{"name":"Cirugia Y Cirujanos","volume":"91 4","pages":"514-520"},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10198264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jorge Martínez-Ulloa-Torres, Paulo Gutiérrez-Torres, Pablo Castro-Ruiz, Patricia B Bolado-García, Mariano Hernandez-Dominguez, Luis F Aguilar-Castillejos, Mauro E Tun-Abraham, Juan P Baas-Cruz
Introduction: Kidney transplantation is the treatment of choice for end-stage renal disease (ESRD). Since March 2020, transplant activity in Mexico has been affected due to the COVID-19 pandemic.
Objective: The aim of the study was to determine the impact on mortality of patients on the waiting list (WL) for cadaveric donor kidney transplantation in a referral hospital in Yucatán, due to suspension of activities due to the pandemic.
Material and methods: Patients over 18 years of age on the waiting list for kidney transplantation at this hospital. In the event of a patient's death, the cause was investigated, especially if it was associated with COVID-19. A two-tailed p ≤ 0.05 was considered significant in all analyzes.
Results: The odds ratio (OR) of death from COVID-19 in a patient with ESRD in the WL in 2020 was OR = 5.04 (95% CI: 1.65-7.14, p = 0.023). The OR of dying with ESRD in the WL with a delay in the follow-up visits was OR = 6.59 (95% CI: 2.7-16.28, p = 0.008).
Conclusion: The probability of death of a patient with ESRD with delayed follow-up visits and transplant retention is statistically higher than the probability of death from COVID-19.
肾移植是治疗终末期肾病(ESRD)的首选方法。自2020年3月以来,由于COVID-19大流行,墨西哥的移植活动受到影响。目的:本研究的目的是确定Yucatán转诊医院因流感大流行而暂停活动对等待尸体供体肾移植的患者死亡率的影响。材料与方法:本院18岁以上肾移植候诊患者。在患者死亡的情况下,会调查原因,特别是与COVID-19有关的原因。所有分析均认为双尾p≤0.05具有显著性。结果:2020年WL中ESRD患者死于COVID-19的优势比(OR)为OR = 5.04 (95% CI: 1.65-7.14, p = 0.023)。在WL中死于ESRD并延迟随访的OR = 6.59 (95% CI: 2.7 ~ 16.28, p = 0.008)。结论:延迟随访并移植保留的ESRD患者死亡概率高于COVID-19死亡概率。
{"title":"Renal transplant waiting list mortality in COVID era: is it advisable to halt transplant activity?","authors":"Jorge Martínez-Ulloa-Torres, Paulo Gutiérrez-Torres, Pablo Castro-Ruiz, Patricia B Bolado-García, Mariano Hernandez-Dominguez, Luis F Aguilar-Castillejos, Mauro E Tun-Abraham, Juan P Baas-Cruz","doi":"10.24875/CIRU.21000718","DOIUrl":"https://doi.org/10.24875/CIRU.21000718","url":null,"abstract":"<p><strong>Introduction: </strong>Kidney transplantation is the treatment of choice for end-stage renal disease (ESRD). Since March 2020, transplant activity in Mexico has been affected due to the COVID-19 pandemic.</p><p><strong>Objective: </strong>The aim of the study was to determine the impact on mortality of patients on the waiting list (WL) for cadaveric donor kidney transplantation in a referral hospital in Yucatán, due to suspension of activities due to the pandemic.</p><p><strong>Material and methods: </strong>Patients over 18 years of age on the waiting list for kidney transplantation at this hospital. In the event of a patient's death, the cause was investigated, especially if it was associated with COVID-19. A two-tailed p ≤ 0.05 was considered significant in all analyzes.</p><p><strong>Results: </strong>The odds ratio (OR) of death from COVID-19 in a patient with ESRD in the WL in 2020 was OR = 5.04 (95% CI: 1.65-7.14, p = 0.023). The OR of dying with ESRD in the WL with a delay in the follow-up visits was OR = 6.59 (95% CI: 2.7-16.28, p = 0.008).</p><p><strong>Conclusion: </strong>The probability of death of a patient with ESRD with delayed follow-up visits and transplant retention is statistically higher than the probability of death from COVID-19.</p>","PeriodicalId":50990,"journal":{"name":"Cirugia Y Cirujanos","volume":"91 4","pages":"507-513"},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10199837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yovana Rodríguez-Maldonado, Teresa Sánchez-Moreno de Juan, Alicia Ruiz-de la Hermosa, Inés Naranjo-Peña, Virginia de Gea-López, Javier Cambronero-Santos
Background: An ostomy significantly influences a person's life, altering their biopsychosocial and sexual sphere and affecting their interpersonal relationships.
Materials and methods: Through an observational, descriptive, and cross-sectional study, with a questionnaire aimed at professionals from a health area in Madrid, we analyzed: sociodemographic variables, knowledge of the professionals on the subject, referral of the patient according to the professional's assessment and feelings that the subject under study produces in the patient and in professionals.
Results: 49% claimed to have no knowledge about sexuality of the ostomyzed patients. 55.9% of those surveyed consider that the healthcare provider is the one who should introduce the topic of sexuality during the clinical interview. 48.5 and 85.2% are unaware of treatments for male and female sexual dysfunction, respectively.
Conclusions: The data show that the training provided in the university centers is insufficient to deal effectively with this issue in the medical consultation. The participants manifest null or minimal knowledge about the sexual sphere in ostomized patients. Knowledge deficiencies are detected in relation to the sexuality of the ostomized patient, difficulty in talking about sex with these patients, and the importance that sanitary professionals give to the patient's sexual sphere, among others.
{"title":"Knowledge of professionals about sexuality of the ostomyzed.","authors":"Yovana Rodríguez-Maldonado, Teresa Sánchez-Moreno de Juan, Alicia Ruiz-de la Hermosa, Inés Naranjo-Peña, Virginia de Gea-López, Javier Cambronero-Santos","doi":"10.24875/CIRU.22000153","DOIUrl":"10.24875/CIRU.22000153","url":null,"abstract":"<p><strong>Background: </strong>An ostomy significantly influences a person's life, altering their biopsychosocial and sexual sphere and affecting their interpersonal relationships.</p><p><strong>Materials and methods: </strong>Through an observational, descriptive, and cross-sectional study, with a questionnaire aimed at professionals from a health area in Madrid, we analyzed: sociodemographic variables, knowledge of the professionals on the subject, referral of the patient according to the professional's assessment and feelings that the subject under study produces in the patient and in professionals.</p><p><strong>Results: </strong>49% claimed to have no knowledge about sexuality of the ostomyzed patients. 55.9% of those surveyed consider that the healthcare provider is the one who should introduce the topic of sexuality during the clinical interview. 48.5 and 85.2% are unaware of treatments for male and female sexual dysfunction, respectively.</p><p><strong>Conclusions: </strong>The data show that the training provided in the university centers is insufficient to deal effectively with this issue in the medical consultation. The participants manifest null or minimal knowledge about the sexual sphere in ostomized patients. Knowledge deficiencies are detected in relation to the sexuality of the ostomized patient, difficulty in talking about sex with these patients, and the importance that sanitary professionals give to the patient's sexual sphere, among others.</p>","PeriodicalId":50990,"journal":{"name":"Cirugia Y Cirujanos","volume":"91 4","pages":"528-534"},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10199838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jesús G Valencia-Martínez, Donovan Reynoso-Saldaña, Ricardo Reynoso-González, David Estrada-Hernández, Mariana Ángeles-Santillán, Viridiana Aja-Sixto
Recurrent gallstone ileus has a recurrence of 2-8.2% with a mortality of 12-20%, secondary to an enteric or cholecystic gallstone. A male patient with a diagnosis of intestinal occlusion secondary to biliary ileus and cholecystoduodenal fistula, performing enterotomy and closure in two planes with drainage placement. Two months after presenting the clinical of intestinal occlusion, medical management began and an abdominal tomography was performed, finding an image suggestive of recurrent gallstone ileus, treated with laparotomy.
{"title":"Gallstone ileus, a rare cause of intestinal occlusion. A case report.","authors":"Jesús G Valencia-Martínez, Donovan Reynoso-Saldaña, Ricardo Reynoso-González, David Estrada-Hernández, Mariana Ángeles-Santillán, Viridiana Aja-Sixto","doi":"10.24875/CIRU.21000678","DOIUrl":"https://doi.org/10.24875/CIRU.21000678","url":null,"abstract":"<p><p>Recurrent gallstone ileus has a recurrence of 2-8.2% with a mortality of 12-20%, secondary to an enteric or cholecystic gallstone. A male patient with a diagnosis of intestinal occlusion secondary to biliary ileus and cholecystoduodenal fistula, performing enterotomy and closure in two planes with drainage placement. Two months after presenting the clinical of intestinal occlusion, medical management began and an abdominal tomography was performed, finding an image suggestive of recurrent gallstone ileus, treated with laparotomy.</p>","PeriodicalId":50990,"journal":{"name":"Cirugia Y Cirujanos","volume":"91 2","pages":"284-289"},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9774777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alejandro F Rodríguez-Mauricio, M Guadalupe Leyva-Cárdenas, Emilio Arch-Tirado, Ana L Lino-González
Background: The acquired brain damage is a common neurological disorder.
Objective: Determine the probabilistic intersections of variables related to acquired brain damage from the determination of a priori and a posteriori probabilities.
Method: Analytical retrospective study. A descriptive analysis was carried out, confidence intervals were calculated to obtain the mean and the proportion with α = 0.05 considering the age of the patient and the diagnosis. An analysis of probabilistic intersection, a priori and a posteriori probability was performed considering diagnosis, sex and age decade; finally, chi squared was calculated.
Results: 736 patients were analyzed. The most frequent diagnosis was language disorder. The patients diagnosed with memory disorder were the youngest and those diagnosed with degenerative cognitive disorder the oldest. The probability that a patient with sequelae due to acquired brain damage arrives at the hospital, at the language pathology service, to be diagnosed with a language disorder and that this patient is also a man is 29.06%.
Conclusions: The high prevalence of short and long-term disability generated by acquired brain damage highlights the importance of an early and timely detection and diagnosis so that it favors prompt and efficient specialized care.
{"title":"Determinación de intersecciones probabilísticas relacionadas con daño cerebral adquirido a partir de la determinación de probabilidades a priori y a posteriori.","authors":"Alejandro F Rodríguez-Mauricio, M Guadalupe Leyva-Cárdenas, Emilio Arch-Tirado, Ana L Lino-González","doi":"10.24875/CIRU.21000291","DOIUrl":"https://doi.org/10.24875/CIRU.21000291","url":null,"abstract":"<p><strong>Background: </strong>The acquired brain damage is a common neurological disorder.</p><p><strong>Objective: </strong>Determine the probabilistic intersections of variables related to acquired brain damage from the determination of a priori and a posteriori probabilities.</p><p><strong>Method: </strong>Analytical retrospective study. A descriptive analysis was carried out, confidence intervals were calculated to obtain the mean and the proportion with α = 0.05 considering the age of the patient and the diagnosis. An analysis of probabilistic intersection, a priori and a posteriori probability was performed considering diagnosis, sex and age decade; finally, chi squared was calculated.</p><p><strong>Results: </strong>736 patients were analyzed. The most frequent diagnosis was language disorder. The patients diagnosed with memory disorder were the youngest and those diagnosed with degenerative cognitive disorder the oldest. The probability that a patient with sequelae due to acquired brain damage arrives at the hospital, at the language pathology service, to be diagnosed with a language disorder and that this patient is also a man is 29.06%.</p><p><strong>Conclusions: </strong>The high prevalence of short and long-term disability generated by acquired brain damage highlights the importance of an early and timely detection and diagnosis so that it favors prompt and efficient specialized care.</p>","PeriodicalId":50990,"journal":{"name":"Cirugia Y Cirujanos","volume":"91 3","pages":"388-396"},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9803993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gerardo Del C Palacios-Saucedo, Juan J Padilla-Martínez, Alejandra G Dávila-Gaytán, Celia G Herrera-Rivera, José M Vázquez-Guillén, Lydia G Rivera-Morales, José R Cortés-Cárdenas, Cristina Rodríguez-Padilla
Objective: To identify factors associated with one-year survival in postoperative glioblastoma patients at a hospital in northeastern Mexico.
Material and methods: Nested case-control study. Patients operated on for glioblastoma between 2016-2019 were included. Information about clinical and surgical factors was obtained, survival was calculated by Kaplan-Meier analysis. Descriptive analysis was performed with medians and ranges, and inferential analysis with χ2, Fisher and Student t test, odds ratio and 95% confidence interval. A value of p < 0.05 was considered significant.
Results: Sixty-two patients with glioblastoma were included, 27 (43.5%) women and 35 (56.5%) men, median age 56 years (range: 6-83). Median survival was 3.6 months (1-52), 45 (72.6%) survived less than 12 months. The factors associated with a higher survival were administration of adjuvant treatment (p < 0.001), better functional status (p = 0.001), and absence of post-surgical complications (p = 0.034).
Conclusions: Most patients with glioblastoma survive less than 12 months and the factors most strongly associated with longer survival are administration of adjuvant treatment, better functional status of the patient and absence of post-surgical complications.
{"title":"Factores asociados a sobrevida a un año en pacientes postoperados de glioblastoma.","authors":"Gerardo Del C Palacios-Saucedo, Juan J Padilla-Martínez, Alejandra G Dávila-Gaytán, Celia G Herrera-Rivera, José M Vázquez-Guillén, Lydia G Rivera-Morales, José R Cortés-Cárdenas, Cristina Rodríguez-Padilla","doi":"10.24875/CIRU.21000130","DOIUrl":"https://doi.org/10.24875/CIRU.21000130","url":null,"abstract":"<p><strong>Objective: </strong>To identify factors associated with one-year survival in postoperative glioblastoma patients at a hospital in northeastern Mexico.</p><p><strong>Material and methods: </strong>Nested case-control study. Patients operated on for glioblastoma between 2016-2019 were included. Information about clinical and surgical factors was obtained, survival was calculated by Kaplan-Meier analysis. Descriptive analysis was performed with medians and ranges, and inferential analysis with χ<sup>2</sup>, Fisher and Student t test, odds ratio and 95% confidence interval. A value of p < 0.05 was considered significant.</p><p><strong>Results: </strong>Sixty-two patients with glioblastoma were included, 27 (43.5%) women and 35 (56.5%) men, median age 56 years (range: 6-83). Median survival was 3.6 months (1-52), 45 (72.6%) survived less than 12 months. The factors associated with a higher survival were administration of adjuvant treatment (p < 0.001), better functional status (p = 0.001), and absence of post-surgical complications (p = 0.034).</p><p><strong>Conclusions: </strong>Most patients with glioblastoma survive less than 12 months and the factors most strongly associated with longer survival are administration of adjuvant treatment, better functional status of the patient and absence of post-surgical complications.</p>","PeriodicalId":50990,"journal":{"name":"Cirugia Y Cirujanos","volume":"91 3","pages":"397-402"},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9811342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Silvia Jiménez-Morales, Carlos J Pérez-Amado, Isela Montúfar-Robles, José M Fragoso, Iván S Aranda-Uribe, David A Ramos-Puga, Ángel E Martínez-Flores, Julián Ramírez-Bello
Coronavirus (CoV) infections cause respiratory and enteric diseases with clinical manifestations ranging from faint to severe, even lead to death of patients. High connectivity between nations and infectivity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), represent a global health problem as the coronavirus disease 19 (COVID-19). This CoV-2 that cause SARS, which appeared in Wuhan, China, in December 2019 originated COVID-19 and declared as pandemic a few months posterior its appearance. In this review, the genomic and spike protein characteristics of SARS-CoV-2, the role of SARS-CoV-2 in the COVID-19 pathogenesis, cytokine storm, the role of cytotoxic T and B cells against SARS-CoV-2, as well as the vaccines efficacy (taking into account mutations in the spike protein) are described.
{"title":"Importance of the SARS-CoV-2 genome and spike protein in the immunopathogenesis of COVID-19 and in the efficacy of vaccines.","authors":"Silvia Jiménez-Morales, Carlos J Pérez-Amado, Isela Montúfar-Robles, José M Fragoso, Iván S Aranda-Uribe, David A Ramos-Puga, Ángel E Martínez-Flores, Julián Ramírez-Bello","doi":"10.24875/CIRU.22000547","DOIUrl":"https://doi.org/10.24875/CIRU.22000547","url":null,"abstract":"<p><p>Coronavirus (CoV) infections cause respiratory and enteric diseases with clinical manifestations ranging from faint to severe, even lead to death of patients. High connectivity between nations and infectivity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), represent a global health problem as the coronavirus disease 19 (COVID-19). This CoV-2 that cause SARS, which appeared in Wuhan, China, in December 2019 originated COVID-19 and declared as pandemic a few months posterior its appearance. In this review, the genomic and spike protein characteristics of SARS-CoV-2, the role of SARS-CoV-2 in the COVID-19 pathogenesis, cytokine storm, the role of cytotoxic T and B cells against SARS-CoV-2, as well as the vaccines efficacy (taking into account mutations in the spike protein) are described.</p>","PeriodicalId":50990,"journal":{"name":"Cirugia Y Cirujanos","volume":"91 2","pages":"268-276"},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9775250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
María F Padilla-Rubio, Miguel Robledo-Valdez, Miguel Morante-Ruiz, Andrea Pérez de Acha-Chávez, Gabino Cervantes-Guevara, Guillermo A Cervantes-Cardona, Sol Ramírez-Ochoa, Gabino Cervantes-Pérez, Alejandro González-Ojeda, Clotilde Fuentes-Orozco, Eduardo Gómez-Sánchez, Enrique Cervantes-Pérez
A polytraumatized patient is defined as one who has multiple lesions involving different organs and systems, which are usually serious and lead to life-threatening respiratory or circulatory dysfunction. Traumatic stress in the polytraumatized patient results in many metabolic changes that are evident from the first days, but usually persist for weeks, requiring adequate nutritional support as they influence outcomes. Nutritional treatment should be a priority in the comprehensive treatment of polytraumatized patients since it attenuates the metabolic response to trauma and prevents the deterioration of body reserves. It should be noted that some patients present previous nutritional risk. Nutritional intervention should be considered at the same level as any other therapy that supports organic functions, especially in patients in the intensive care unit. Nutritional intervention in polytraumatized patients is a pillar of treatment that has multiple benefits and can improve prognosis. All efforts must be aimed at the early detection of malnourished patients at nutritional risk and providing timely therapies that improve clinical outcomes.
{"title":"Terapia médico-nutricional en pacientes politraumatizados: una carrera contra el tiempo.","authors":"María F Padilla-Rubio, Miguel Robledo-Valdez, Miguel Morante-Ruiz, Andrea Pérez de Acha-Chávez, Gabino Cervantes-Guevara, Guillermo A Cervantes-Cardona, Sol Ramírez-Ochoa, Gabino Cervantes-Pérez, Alejandro González-Ojeda, Clotilde Fuentes-Orozco, Eduardo Gómez-Sánchez, Enrique Cervantes-Pérez","doi":"10.24875/CIRU.220001901","DOIUrl":"https://doi.org/10.24875/CIRU.220001901","url":null,"abstract":"<p><p>A polytraumatized patient is defined as one who has multiple lesions involving different organs and systems, which are usually serious and lead to life-threatening respiratory or circulatory dysfunction. Traumatic stress in the polytraumatized patient results in many metabolic changes that are evident from the first days, but usually persist for weeks, requiring adequate nutritional support as they influence outcomes. Nutritional treatment should be a priority in the comprehensive treatment of polytraumatized patients since it attenuates the metabolic response to trauma and prevents the deterioration of body reserves. It should be noted that some patients present previous nutritional risk. Nutritional intervention should be considered at the same level as any other therapy that supports organic functions, especially in patients in the intensive care unit. Nutritional intervention in polytraumatized patients is a pillar of treatment that has multiple benefits and can improve prognosis. All efforts must be aimed at the early detection of malnourished patients at nutritional risk and providing timely therapies that improve clinical outcomes.</p>","PeriodicalId":50990,"journal":{"name":"Cirugia Y Cirujanos","volume":"91 1","pages":"122-130"},"PeriodicalIF":0.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10720080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}