Current Problems in Cardiology最新文献

英文中文

Sex differences in in-hospital outcomes in hypertrophic cardiomyopathy: A nationwide analysis 肥厚性心肌病住院结果的性别差异：一项全国性分析

IF 3.3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Current Problems in Cardiology

Pub Date : 2025-09-10 DOI: 10.1016/j.cpcardiol.2025.103172

Ahmed M. Saad MD , Mohammed Abozenah MD , Colby Salerno DO , Andrew M. Goldsweig MD, MS

Background

Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiomyopathy. HCM is associated with heart failure (HF), arrhythmia, and acute coronary syndrome (ACS). The influence of sex on in-hospital outcomes in HCM is unknown. We conducted a nationwide analysis to compare outcomes between women and men with HCM hospitalized for HF, arrhythmias, or ACS.

Methods

This retrospective cohort analysis of the 2022 National Inpatient Sample (NIS) identified adults hospitalized with acute HF, arrhythmia, or ACS plus a secondary diagnosis of HCM. The primary outcome was in-hospital mortality. Secondary outcomes included length of stay (LOS) and total hospital charges. Multivariable logistic and linear regression models were used to adjust for demographics and comorbidities.

Results

Among 5,089 HCM admissions (51.1 % female; mean age 65.9 years), women were older (68.9 vs. 62.1 years) and more often admitted for acute HF. Arrhythmia presentations were similarly common in both sexes, and men more frequently had ACS. In-hospital mortality was 1.7 % and did not differ by sex after adjustment (adjusted odds ratio 1.3, p = 0.63). Mean LOS was 4.3 days and was similar between sexes. Total hospitalization charges showed no significant sex difference for HF or ACS, but men incurred higher charges for arrhythmias.

Conclusions

In this nationwide analysis, sex was not an independent predictor of in-hospital mortality or LOS among admissions with HCM and acute cardiovascular events. Resource utilization was broadly comparable except for arrhythmia admissions, where charges were substantially higher in men. Differences in hospital charges suggest that differences in management may exist.

背景：肥厚性心肌病（HCM）是最常见的遗传性心肌病。HCM与心力衰竭（HF）、心律失常和急性冠状动脉综合征（ACS）有关。性别对HCM患者住院结果的影响尚不清楚。我们进行了一项全国性的分析，比较因HF、心律失常或ACS住院的HCM患者的男女预后。方法：对2022年全国住院患者样本（NIS）进行回顾性队列分析，确定了急性心衰、心律失常或ACS合并HCM的住院成年人。主要终点是住院死亡率。次要结局包括住院时间（LOS）和总住院费用。使用多变量logistic和线性回归模型来调整人口统计学和合并症。结果：在5089例HCM入院患者中（51.1%为女性，平均年龄65.9岁），女性年龄较大（68.9岁对62.1岁），且更常因急性心衰入院。心律失常的表现在两性中同样常见，男性更常患有ACS。住院死亡率为1.7%，校正后性别差异无统计学意义（校正优势比为1.3,p=0.63）。平均生存期为4.3天，两性之间相似。HF和ACS的总住院费用无显著性差异，但男性因心律失常的住院费用较高。结论：在这项全国性的分析中，性别不是HCM和急性心血管事件入院患者的住院死亡率或LOS的独立预测因子。除了心律失常入院外，资源利用率大致相当，其中男性收费高得多。医院收费的差异表明可能存在管理上的差异。

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引用次数: 0

Knowledge mapping of SGLT2-inhibitors and cardiovascular outcomes: A bibliometric analysis sglt2抑制剂与心血管结局的知识图谱：文献计量学分析。

IF 3.3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Current Problems in Cardiology

Pub Date : 2025-09-10 DOI: 10.1016/j.cpcardiol.2025.103171

Aysa Rezabakhsh , Hadis Iraji , Ashot Avagimyan , Elena Aghajanova , Zinaida Jndoyan , Lilia Mirzoyan , Waseem Hassan , Solomon Habtemariam , Anne Meddahi-Pellé , Graciela Pavon-Djavid , Abolfazl Barzegri

Introduction

Initially developed for the treatment of type 2 diabetes mellitus (T2DM), SGLT2 inhibitors have increasingly been recognized for their substantial cardiovascular, renal, and metabolic benefits. This study undertakes a systematic bibliometric analysis to delineate research trends, quantify advancements, and identify influential studies on SGLT2 inhibitors and cardiovascular outcomes.

Methods

A comprehensive literature search was performed using the Scopus database, resulting in 10,211 documents up to the search date. Both original research articles and reviews (narrative and systematic) were included. Quantitative metrics such as publication count, citation analysis, and authorship were employed. Network visualization tools (e.g., VOSviewer) and bibliometric software (R Studio with bibliometrix packages) were used to analyze collaboration networks, keyword co-occurrence, and thematic clustering.

Results

The analysis revealed a significant upward trend in publication volume, with a notable peak in recent years, indicating a heightened interest in the topic among scientists. The United States and selected European institutions emerged as major contributors, with prominent authors and funding sources influencing the research output. Thematic analysis highlighted a focus on cardiovascular diseases, heart failure, renal outcomes, and mechanistic studies of SGLT2 inhibitor action. Notably, landmark randomized controlled trials have reported significant reductions in cardiovascular mortality, heart failure hospitalizations, and progression of kidney disease.

Conclusion

This study underscores the transformative impact of SGLT2 inhibitors on cardiovascular therapy. The analytical framework highlights the expansion of the field, and the integration of translational research.

SGLT2抑制剂最初是为治疗2型糖尿病（T2DM）而开发的，现已越来越多地因其在心血管、肾脏和代谢方面的重大益处而得到认可。本研究进行了系统的文献计量分析，以描述研究趋势，量化进展，并确定SGLT2抑制剂和心血管结局的影响研究。方法：利用Scopus数据库进行全面的文献检索，截至检索日期共检索文献10211篇。包括原始研究文章和评论（叙述性和系统性）。定量指标，如发表数，引文分析和作者被采用。使用网络可视化工具（如VOSviewer）和文献计量软件（带有bibliometrix软件包的R Studio）分析协作网络、关键词共现和主题聚类。结果：分析显示，出版物数量呈显著上升趋势，近年来出现了一个显著的高峰，表明科学家对该主题的兴趣日益浓厚。美国和部分欧洲机构成为主要贡献者，其著名作者和资金来源影响着研究成果。专题分析强调了心血管疾病、心力衰竭、肾脏结局和SGLT2抑制剂作用机制研究的重点。值得注意的是，具有里程碑意义的随机对照试验报告了心血管死亡率、心力衰竭住院率和肾脏疾病进展的显著降低。结论：本研究强调了SGLT2抑制剂对心血管治疗的变革性影响。分析框架突出了领域的拓展，以及转化研究的整合。

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引用次数: 0

The triadic relationship between nonalcoholic fatty liver disease, type 2 diabetes, and cardiovascular disease: From molecular mechanisms to clinical management 非酒精性脂肪肝、2型糖尿病和心血管疾病的三位一体关系：从分子机制到临床管理

IF 3.3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Current Problems in Cardiology

Pub Date : 2025-09-03 DOI: 10.1016/j.cpcardiol.2025.103170

Yuxi Jin , Mohammed Alissa , Ahmed Ezzat Ahmed , Amin A. Al-Doaiss , Naif Asiri , Yasser Assiri , Shahid Ullah Khan Phd , Munir Ullah Khan , Samuel Joseph

Nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes mellitus (T2DM) represent interconnected metabolic disorders with multifaceted etiology, demonstrating bidirectional relationships and pronounced associations with cardiovascular diseases (CVDs). Despite extensive research, significant knowledge gaps persist regarding the temporal progression of these comorbidities, optimal screening strategies for high-risk populations, and personalized therapeutic approaches targeting the hepatic-cardiac-metabolic axis simultaneously. Current literature lacks a comprehensive analysis of phenotypic heterogeneity within NAFLD-T2DM-CVD clusters and fails to address sex-specific and ethnic variations in disease progression patterns adequately. A systematic literature search was conducted across PubMed, Medline, Embase, Web of Science, and Google Scholar databases from inception to June 2024, employing various combinations of terms including NAFLD, NASH, T2DM, and CVDs, with emphasis on identifying mechanistic pathways, epidemiological trends, and therapeutic innovations. This review identifies novel pathophysiological mechanisms linking hepatic steatosis, insulin resistance, and cardiovascular dysfunction, including previously underexplored roles of gut microbiome dysbiosis, advanced glycation end products, and epigenetic modifications. Emerging evidence suggests distinct molecular signatures that could facilitate precision medicine approaches. The intricate interplay between diabetes, hepatic dysfunction, and cardiovascular complications represents a global health challenge requiring integrated management strategies. Future research should prioritize developing biomarker-guided therapeutic algorithms, investigating sex-specific treatment responses, and establishing standardized protocols for concurrent NAFLD-T2DM-CVD management to optimize clinical outcomes and reduce healthcare burden.

非酒精性脂肪性肝病（NAFLD）和2型糖尿病（T2DM）是具有多方面病因的相互关联的代谢性疾病，与心血管疾病（cvd）表现出双向关系和明显的相关性。尽管进行了广泛的研究，但关于这些合并症的时间进展，高危人群的最佳筛查策略以及同时针对肝-心-代谢轴的个性化治疗方法，仍然存在重大的知识空白。目前的文献缺乏对NAFLD-T2DM-CVD集群表型异质性的全面分析，未能充分解决疾病进展模式的性别特异性和种族差异。系统地检索了PubMed、Medline、Embase、Web of Science和谷歌Scholar数据库，检索时间从成立到2024年6月，检索了包括NAFLD、NASH、T2DM和cvd在内的各种术语组合，重点是确定机制途径、流行病学趋势和治疗创新。本综述确定了与肝脂肪变性、胰岛素抵抗和心血管功能障碍相关的新的病理生理机制，包括以前未被充分探索的肠道微生物群失调、晚期糖基化终产物和表观遗传修饰的作用。新出现的证据表明，不同的分子特征可以促进精准医疗方法。糖尿病、肝功能障碍和心血管并发症之间错综复杂的相互作用是一项全球健康挑战，需要综合管理策略。未来的研究应优先开发生物标志物引导的治疗算法，调查性别特异性治疗反应，并建立NAFLD-T2DM-CVD并发管理的标准化方案，以优化临床结果并减轻医疗负担。

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引用次数: 0

HER2-targeted therapies and cardiotoxicity: From major concern to manageable risk her2靶向治疗和心脏毒性：从主要关注到可控风险。

IF 3.3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Current Problems in Cardiology

Pub Date : 2025-09-03 DOI: 10.1016/j.cpcardiol.2025.103168

Rio Putra Pamungkas MD , Laras Pratiwi MD , Henry Sutanto MD, MSc, PhD

HER2-targeted therapies have dramatically improved outcomes for patients with HER2-positive breast cancer, but their potential for cardiotoxicity remains a critical clinical concern. Early trials reported high rates of cardiac dysfunction, particularly with concomitant anthracycline use, prompting the development of intensive cardiac monitoring strategies. However, emerging evidence suggests that most cardiotoxic events are asymptomatic, reversible, and rarely require permanent treatment discontinuation, particularly with newer agents such as antibody–drug conjugates. Clinical determinants include baseline left ventricular dysfunction, age, comorbidities, and combination chemotherapy, while biomarkers and advanced imaging are promising tools for early detection. Mechanistically, HER2 inhibition disrupts cardiomyocyte survival pathways and mitochondrial function, but the relationship between these changes and clinically meaningful heart failure remains incompletely defined. Recent studies, including SAFE-HEaRt, demonstrate that HER2 therapy can often be safely continued under cardio-oncology supervision with appropriate cardioprotective interventions. Nevertheless, gaps persist in risk stratification, long-term surveillance, and the integration of biomarkers and imaging into routine practice. This article critically examines the pathophysiology, clinical risk factors, and management of HER2 therapy-induced cardiotoxicity, ultimately arguing that with proper monitoring and multidisciplinary care, cardiotoxicity should not preclude optimal oncologic treatment.

her2靶向治疗显著改善了her2阳性乳腺癌患者的预后，但其潜在的心脏毒性仍然是一个关键的临床问题。早期的试验报告了心功能障碍的高发率，特别是与蒽环类药物的同时使用，促使了强化心脏监测策略的发展。然而，新出现的证据表明，大多数心脏毒性事件是无症状的，可逆的，很少需要永久停止治疗，特别是使用新的药物，如抗体-药物偶联物。临床决定因素包括基线左心室功能障碍、年龄、合并症和联合化疗，而生物标志物和先进的成像是早期发现的有希望的工具。从机制上讲，HER2抑制会破坏心肌细胞存活途径和线粒体功能，但这些变化与临床意义上的心力衰竭之间的关系仍不完全明确。包括SAFE-HEaRt在内的近期研究表明，在心脏肿瘤学监督下，适当的心脏保护干预措施通常可以安全地继续进行HER2治疗。然而，在风险分层、长期监测以及将生物标志物和成像纳入常规实践方面仍然存在差距。本文严格检查了HER2治疗诱导的心脏毒性的病理生理学、临床危险因素和管理，最终认为通过适当的监测和多学科护理，心脏毒性不应排除最佳的肿瘤治疗。

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引用次数: 0

The effect of 0.5 mg dose of colchicine on clinical outcomes in patients with acute myocardial infarction: An updated meta-analysis of randomized controlled trials 0.5 mg秋水仙碱对急性心肌梗死患者临床结局的影响：一项随机对照试验的最新荟萃分析

IF 3.3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Current Problems in Cardiology

Pub Date : 2025-09-03 DOI: 10.1016/j.cpcardiol.2025.103169

Ahmed Nazmy MD , Ahmed Sobhy MD , Ahmed Elshahat MD , Karim Atta MD , Mohamed R. Murad MD , Moustafa Ibrahim MD , Hassan El-Shirbiny MD , Rahma Abdelfattah Ibrahim MD , Mohamed Saad Sayed MD , Mahmoud Gomaa MD , Ahmed Yasser Shaban MD , Mohamed Naeem MD , Ahmed Abdelaziz MD

Background

Inflammation plays a critical role in the progression of atherosclerosis, and the anti-inflammatory effects on clinical outcomes of patients with acute myocardial infarction (AMI) are still uncertain.

Objectives

We aimed to study the effects of a 0.5 mg dose of colchicine on clinical outcomes following AMI.

Methods

We systematically searched PubMed, Scopus, Web of Science, and Cochrane Central from inception to January 2025 for randomized controlled trials (RCTs) assessing 0.5 mg colchicine in AMI patients. The primary outcome was the incidence of major adverse cardiovascular events (MACE). Secondary outcomes included individual MACE components, cardiovascular (CV) and non-CV mortality, atrial fibrillation (AF), hospital readmission, and gastrointestinal (GIT) adverse events, including diarrhea.

Results

Ten RCTs involving 13,623 patients with a median follow-up of 6 months (range 5 days–36 months) were included. Low-dose colchicine showed a non-significant trend toward reducing MACE versus placebo (RR = 0.90, 95% CI: 0.80–1.01, p = 0.07; I² = 0%). Hospital readmission was significantly reduced by 49% (OR = 0.51, 95% CI: 0.26–0.98, p = 0.04; number needed to treat [NNT] = 25). Colchicine increased the risk of diarrhea (RR = 1.58, 95% CI: 1.06–2.36, p = 0.03; I² = 71%; number needed to harm [NNH] = 50) but showed no significant differences in all-cause mortality, CV mortality, myocardial infarction, stroke, or other GIT events.

Conclusion

Low-dose colchicine had a lower hospital readmission rate, but with higher rates of diarrhea compared to placebo. Long-term assessment is indeed to validate the current findings.

背景：炎症在动脉粥样硬化的进展中起着至关重要的作用，抗炎对急性心肌梗死（AMI）患者临床结局的影响尚不确定。目的：研究0.5 mg秋水仙碱对急性心肌梗死后临床预后的影响。方法：我们系统地检索PubMed、Scopus、Web of Science和Cochrane Central从成立到2025年1月的随机对照试验（rct），评估0.5 mg秋水仙碱对AMI患者的影响。主要终点是主要不良心血管事件（MACE）的发生率。次要结局包括个体MACE成分、心血管（CV）和非CV死亡率、心房颤动（AF）、再入院和胃肠道（GIT）不良事件，包括腹泻。结果：纳入10项随机对照试验，涉及13,623例患者，中位随访时间为6个月（5天-36个月）。与安慰剂相比，低剂量秋水仙碱降低MACE的趋势不显著（RR = 0.90,95% CI: 0.80-1.01, p = 0.07;I² = 0%）。再入院率显著降低49% （OR = 0.51,95% CI: 0.26-0.98, p = 0.04；所需治疗人数[NNT] = 25）。秋水仙碱增加了腹泻的风险（RR = 1.58,95% CI: 1.06-2.36, p = 0.03;I² = 71%；所需伤害数[NNH] = 50），但在全因死亡率、CV死亡率、心肌梗死、卒中或其他GIT事件方面无显著差异。结论：与安慰剂相比，低剂量秋水仙碱的再入院率较低，但腹泻率较高。长期评估确实验证了目前的发现。

{"title":"The effect of 0.5 mg dose of colchicine on clinical outcomes in patients with acute myocardial infarction: An updated meta-analysis of randomized controlled trials","authors":"Ahmed Nazmy MD , Ahmed Sobhy MD , Ahmed Elshahat MD , Karim Atta MD , Mohamed R. Murad MD , Moustafa Ibrahim MD , Hassan El-Shirbiny MD , Rahma Abdelfattah Ibrahim MD , Mohamed Saad Sayed MD , Mahmoud Gomaa MD , Ahmed Yasser Shaban MD , Mohamed Naeem MD , Ahmed Abdelaziz MD","doi":"10.1016/j.cpcardiol.2025.103169","DOIUrl":"10.1016/j.cpcardiol.2025.103169","url":null,"abstract":"<div><h3>Background</h3><div>Inflammation plays a critical role in the progression of atherosclerosis, and the anti-inflammatory effects on clinical outcomes of patients with acute myocardial infarction (AMI) are still uncertain.</div></div><div><h3>Objectives</h3><div>We aimed to study the effects of a 0.5 mg dose of colchicine on clinical outcomes following AMI.</div></div><div><h3>Methods</h3><div>We systematically searched PubMed, Scopus, Web of Science, and Cochrane Central from inception to January 2025 for randomized controlled trials (RCTs) assessing 0.5 mg colchicine in AMI patients. The primary outcome was the incidence of major adverse cardiovascular events (MACE). Secondary outcomes included individual MACE components, cardiovascular (CV) and non-CV mortality, atrial fibrillation (AF), hospital readmission, and gastrointestinal (GIT) adverse events, including diarrhea.</div></div><div><h3>Results</h3><div>Ten RCTs involving 13,623 patients with a median follow-up of 6 months (range 5 days–36 months) were included. Low-dose colchicine showed a non-significant trend toward reducing MACE versus placebo (RR = 0.90, 95% CI: 0.80–1.01, p = 0.07; I² = 0%). Hospital readmission was significantly reduced by 49% (OR = 0.51, 95% CI: 0.26–0.98, p = 0.04; number needed to treat [NNT] = 25). Colchicine increased the risk of diarrhea (RR = 1.58, 95% CI: 1.06–2.36, p = 0.03; I² = 71%; number needed to harm [NNH] = 50) but showed no significant differences in all-cause mortality, CV mortality, myocardial infarction, stroke, or other GIT events.</div></div><div><h3>Conclusion</h3><div>Low-dose colchicine had a lower hospital readmission rate, but with higher rates of diarrhea compared to placebo. Long-term assessment is indeed to validate the current findings.</div></div>","PeriodicalId":51006,"journal":{"name":"Current Problems in Cardiology","volume":"50 11","pages":"Article 103169"},"PeriodicalIF":3.3,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145006813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Editor’s Message 编辑器’的消息

IF 3.3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Current Problems in Cardiology

Pub Date : 2025-09-02 DOI: 10.1016/S0146-2806(25)00179-3

引用次数: 0

Guidelines for Authors 作者指南

IF 3.3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Current Problems in Cardiology

Pub Date : 2025-09-02 DOI: 10.1016/S0146-2806(25)00182-3

引用次数: 0

Information for Readers 读者资讯

IF 3.3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Current Problems in Cardiology

Pub Date : 2025-09-02 DOI: 10.1016/S0146-2806(25)00181-1

引用次数: 0

Title Page 标题页

IF 3.3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Current Problems in Cardiology

Pub Date : 2025-09-02 DOI: 10.1016/S0146-2806(25)00178-1

引用次数: 0

The top 100 most cited articles in cardiovascular research: A bibliometric perspective 心血管研究中被引用最多的100篇文章：文献计量学视角

IF 3.3 3区医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Current Problems in Cardiology

Pub Date : 2025-08-25 DOI: 10.1016/j.cpcardiol.2025.103153

Siddig Ibrahim Abdelwahab , Manal Mohamed Elhassan Taha , Abdullah Farasani , Jobran M Moshi , Ahmad Assiri , Saeed Alshahrani , Khaled A Sahli , Hussam M. Shubaily , Waseem Hassan

Objective

The aim is to analyze the citation dynamics, and research focus of the top 100 most cited cardiovascular research.

Methods

Data were retrieved from the Scopus database in January 2025, focusing on journals containing the term “cardio” in their title. Only original research articles and reviews were included. The data were analyzed using VOSviewer and R Studio to assess co-authorship networks, keyword co-occurrence, citation mapping, and citation impact indicators.

Results

A total of 100 articles, published between 1967 and 2020, were included in the analysis. These articles had an average of 2,285 citations each. The growth rate of publications was 3.74 %, with an average document age of 20.8 years. Collaboration was extensive, with 1,653 authors contributing to these papers, and 25 % of publications involved international collaboration. Citation analysis showed increasing citation rates over time, with recent papers achieving significant impact in a short period. The top authors, universities, countries, and sources of publication were identified, revealing the global nature of cardiovascular research and its collaborative nature. The title co-words analysis was also performed to understand the main focus of the most cited papers.

Conclusions

This study offers a deeper understanding of the most cited cardiovascular research papers, addressing gaps in previous bibliometric studies by providing insights into citation dynamics, author collaborations, and thematic shifts. Future studies should explore the quality of research and expand the scope of bibliometric analyses.

目的分析被引频次前100位的心血管科学研究的被引动态及研究热点。方法于2025年1月从Scopus数据库中检索，重点检索标题中包含cardio一词的期刊。仅纳入原创研究文章和综述。使用VOSviewer和R Studio对数据进行分析，评估合著网络、关键词共现、引文映射和引文影响指标。结果共纳入1967 - 2020年间发表的100篇文献。这些文章平均每篇被引用2285次。发文量增长率为3.74%，平均文献年龄为20.8年。合作非常广泛，有1653位作者对这些论文做出了贡献，25%的出版物涉及国际合作。引文分析显示，随着时间的推移，被引率呈上升趋势，近期论文在短时间内产生显著影响。确定了顶级作者、大学、国家和出版物来源，揭示了心血管研究的全球性质及其合作性质。还进行了标题共词分析，以了解被引次数最多的论文的主要焦点。本研究提供了对被引用最多的心血管研究论文的更深入了解，通过提供对引用动态、作者合作和主题变化的见解，解决了以前文献计量学研究中的空白。未来的研究应探索研究的质量，并扩大文献计量分析的范围。

{"title":"The top 100 most cited articles in cardiovascular research: A bibliometric perspective","authors":"Siddig Ibrahim Abdelwahab , Manal Mohamed Elhassan Taha , Abdullah Farasani , Jobran M Moshi , Ahmad Assiri , Saeed Alshahrani , Khaled A Sahli , Hussam M. Shubaily , Waseem Hassan","doi":"10.1016/j.cpcardiol.2025.103153","DOIUrl":"10.1016/j.cpcardiol.2025.103153","url":null,"abstract":"<div><h3>Objective</h3><div>The aim is to analyze the citation dynamics, and research focus of the top 100 most cited cardiovascular research.</div></div><div><h3>Methods</h3><div>Data were retrieved from the Scopus database in January 2025, focusing on journals containing the term “cardio” in their title. Only original research articles and reviews were included. The data were analyzed using VOSviewer and R Studio to assess co-authorship networks, keyword co-occurrence, citation mapping, and citation impact indicators.</div></div><div><h3>Results</h3><div>A total of 100 articles, published between 1967 and 2020, were included in the analysis. These articles had an average of 2,285 citations each. The growth rate of publications was 3.74 %, with an average document age of 20.8 years. Collaboration was extensive, with 1,653 authors contributing to these papers, and 25 % of publications involved international collaboration. Citation analysis showed increasing citation rates over time, with recent papers achieving significant impact in a short period. The top authors, universities, countries, and sources of publication were identified, revealing the global nature of cardiovascular research and its collaborative nature. The title co-words analysis was also performed to understand the main focus of the most cited papers.</div></div><div><h3>Conclusions</h3><div>This study offers a deeper understanding of the most cited cardiovascular research papers, addressing gaps in previous bibliometric studies by providing insights into citation dynamics, author collaborations, and thematic shifts. Future studies should explore the quality of research and expand the scope of bibliometric analyses.</div></div>","PeriodicalId":51006,"journal":{"name":"Current Problems in Cardiology","volume":"50 11","pages":"Article 103153"},"PeriodicalIF":3.3,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144933731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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