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Tofacitinib for fibrosing alopecia in a pattern distribution 托法替尼治疗纤维性斑秃
Pub Date : 2024-08-08 DOI: 10.25259/ijdvl_655_2024
Rui Wu, Yuanwen Li, Lei Wang, Zhishan Yang, Qingwu Liu, Dingquan Yang
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引用次数: 0
Direct immunofluorescence demystified: Essential insights and recent advances for dermatologists 直接免疫荧光解密:皮肤科医生的基本见解和最新进展
Pub Date : 2024-08-08 DOI: 10.25259/ijdvl_95_2024
M. Phiske, G. Khullar, J. Padhiyar, Abhineetha Hosthota, Debajyoti Chatterjee
Direct immunofluorescence (DIF) is widely used in dermatopathology for the diagnosis of autoimmune blistering diseases (AIBDs), cutaneous vasculitis, and connective tissue disorders. Although it is easy and useful to perform, it needs technical expertise and experience for proper interpretation. The yield of DIF depends on multiple factors including the adequacy, transportation, storage, processing, and interpretation of the biopsy specimen. Effective collaboration between the dermatologist and dermatopathologist along with meticulous clinico-pathological correlation is crucial for accurately interpreting DIF in the appropriate clinical context.In this narrative review of DIF in dermatology, we discuss the indications of DIF, recent updates on the selection of optimum biopsy sites, basic techniques of DIF including the classical transport medium and its alternatives, processing and staining technique, patterns in various diseases, advancements such as serration pattern analysis, and latest recommendations on the use of DIF in cutaneous disorders.
直接免疫荧光(DIF)在皮肤病理学中被广泛用于诊断自身免疫性水疱病(AIBD)、皮肤血管炎和结缔组织疾病。虽然这种方法简单实用,但需要专业技术和经验才能正确解读。DIF 的结果取决于多种因素,包括活检标本的充分性、运输、储存、处理和判读。在这篇关于皮肤科 DIF 的叙述性综述中,我们讨论了 DIF 的适应症、最佳活检部位选择的最新进展、DIF 的基本技术(包括经典运输介质及其替代品)、处理和染色技术、各种疾病的模式、锯齿状模式分析等进展,以及关于在皮肤疾病中使用 DIF 的最新建议。
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引用次数: 0
A case of cyclophosphamide-induced euprolactinemic galactorrhea 一例环磷酰胺诱发的高泌乳素血症性半乳溢乳症
Pub Date : 2024-08-08 DOI: 10.25259/ijdvl_535_2024
Kirti Jangid, S. Tambe, Shraddha Mahobia, Samira Siddiqui Khatoon Mohd Hanif
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引用次数: 0
A life-threatening consequence of erythema nodosum leprosum 麻风结节性红斑的一种危及生命的后果
Pub Date : 2024-08-08 DOI: 10.25259/ijdvl_18_2024
Kittu Malhi, Lovish Singla, Aminder Singh, Sukhjot Kaur
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引用次数: 0
Role of cosmetic camouflage in improving quality of life in dermatological disorders: A narrative review 化妆品伪装在提高皮肤病患者生活质量方面的作用:叙述性综述
Pub Date : 2024-07-27 DOI: 10.25259/ijdvl_1117_2023
Astha Arora, Mala Bhalla
Camouflage is a system of techniques using cosmetics to conceal, diminish and disguise visible disfigurements of pigment or texture of skin mainly over visible areas. A wide variety of options are available which can be used as camouflage cosmetics. Over the years many authors have published studies highlighting the importance of camouflage in different dermatological disorders like pigmentary, vascular, scars, acne vulgaris and many more. In this review we present 15 such studies assessing QOL in patients of dermatological diseases who were given camouflage therapy. The evidence presented here gives us an insight into the positive effects of camouflage/cover up make up when offered to patients with different dermatological conditions.
遮瑕是一种使用化妆品来掩盖、减弱和伪装皮肤色素或纹理的明显瑕疵的技术体系,主要用于明显部位。可用于遮瑕的化妆品种类繁多。多年来,许多学者发表了研究报告,强调了遮瑕对于色素性、血管性、疤痕、寻常痤疮等不同皮肤病的重要性。在这篇综述中,我们介绍了 15 项此类研究,对接受伪装治疗的皮肤病患者的 QOL 进行了评估。本文提供的证据让我们深入了解了为不同皮肤病患者提供遮瑕/遮盖化妆品的积极效果。
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引用次数: 0
Recurrence rates after functional surgery versus amputation for nail squamous cell carcinoma not involving the bone: A systematic review 非累及骨骼的指甲鳞状细胞癌功能性手术与截肢术后的复发率:系统性综述
Pub Date : 2024-07-27 DOI: 10.25259/ijdvl_912_2023
Hoi-Shiwn Wong, Fang Li, Jia-Yi Jiang, Shu-dai Huang, Xiang Ji, Ping Zhu, Da-Guang Wang
Nail unit squamous cell carcinoma (nSCC) is a malignant subungual tumour. Although it has a low risk of metastasis and mortality, the tumour has a significant local recurrence rate. There is insufficient data to determine whether functional surgery is less effective than amputation for nSCC that does not involve the bone.We aimed to investigate existing data on the outcomes of functional surgery and amputation for nSCC without bone invasion.We carried out an extensive search in PubMed, Embase, Cochrane Library, Web of Science, and Scopus for appropriate English-language academic papers, starting with the creation of individual resources until February 23, 2023. The main outcome was local recurrence. Initially, 2191 studies related to nSCC were selected. Information from every research study was retrieved and subdivided, comprising the year of publication, period, number of patients, age, gender distribution, tumour stage, type of intervention, number of recurrences, and follow-up period.Ten independent studies (319 lesions) were finally selected. Mohs micrographic surgery was the most reported surgical modality, followed by wide surgical excision and amputation. Local recurrence rates between Mohs micrographic surgery, wide surgical excision and amputation treatment were nearly identical. Other surgical methods included limited surgical excision, partial ablation, and limited excision until the clearing of margins, with recurrence rates up to 50%.Given the functional impairment and psychological distress associated with phalanx amputation, functional surgery, including Mohs micrographic surgery and wide surgical excision , should be the preferred therapy for nSCC without bone involvement. Amputation should remain the preferred therapy for nSCC that involves the bone. Partial excision should be avoided. Further studies on whether Mohs micrographic surgery or wide surgical excision is a better option for nSCC not involving the bone are required.
甲单位鳞状细胞癌(nSCC)是一种甲下恶性肿瘤。虽然其转移和死亡风险较低,但肿瘤的局部复发率很高。我们在PubMed、Embase、Cochrane图书馆、Web of Science和Scopus上广泛搜索了相关的英文学术论文,从创建单个资源开始,直至2023年2月23日。主要结果为局部复发。初步筛选出 2191 项与 nSCC 相关的研究。对每项研究的信息进行检索和细分,包括发表年份、时期、患者人数、年龄、性别分布、肿瘤分期、干预类型、复发次数和随访时间。莫氏显微外科手术是报道最多的手术方式,其次是大范围手术切除和截肢。莫氏显微手术、广泛手术切除和截肢治疗的局部复发率几乎相同。其他手术方法包括局限性手术切除、部分消融和局限性切除,直到边缘清晰为止,复发率高达 50%。考虑到指骨截肢带来的功能障碍和心理压力,功能性手术,包括莫氏显微外科手术和广泛手术切除,应成为无骨受累 nSCC 的首选疗法。截肢仍应是治疗累及骨骼的 nSCC 的首选疗法。应避免部分切除。对于未累及骨骼的 nSCC,Mohs 显微手术还是广泛手术切除是更好的选择,还需要进一步研究。
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引用次数: 0
Syphilitic onychopathy: Clinical and onychoscopy findings 梅毒性咽峡炎:临床和耳镜检查结果
Pub Date : 2024-07-27 DOI: 10.25259/ijdvl_1289_2023
Bharti Aggarwal, Archana Singal
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引用次数: 0
Deciphering the landscape of hereditary angioedema in India: Perspective for Indian dermatologists 解读印度遗传性血管性水肿的现状:印度皮肤科医生的视角
Pub Date : 2024-07-27 DOI: 10.25259/ijdvl_1002_2023
P. Barman, Gayathri Cv, Rashmi Sarkar, M. Shenoy, A. K. Jindal, Sunil Dogra
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引用次数: 0
Linear and annular lupus panniculitis of the scalp 头皮的线状和环状狼疮性泛发炎
Pub Date : 2024-07-26 DOI: 10.25259/ijdvl_276_2024
Ruiying Wu, Zhishan Yang, Dingquan Yang
5. Knoll LD, Segura JW, Benson Jr RC, Goellner JR. Bowenoid papulosis of the penis: successful management with neodymium:YAG laser. J Urol. 1988;139:1307--9. 6. Colombel M, Pedron P, Missirlu A, Abbou C, Chopin D. Vesicovaginal fistula after laser vaporization of vaginal condyloma. J Urol. 1995;154:1860. 7. Tschanz C, Salomon D, Skaria A, Masouye I, Vecchietti GL, Harms M. Vulvodynia after CO2 laser treatment of the female genital mucosa. Dermatology. 2001;202:371--2. 8. Savoca S, Nardo LG, Rosano TF, D‘Agosta S, Nardo F. CO(2) laser vaporization as primary therapy for human papillomavirus lesions. A prospective observational study. Acta Obstet Gynecol Scand. 2001;80:1121--4. 9. Lassus J, Happonen HP, Niemi KM, Ranki A. Carbon dioxide (CO2)-laser therapy cures macroscopic lesions, but viral genome is not eradicated in men with therapy-resistant HPV infection. Sex Transm Dis. 1994;21:297--302. 10. Aynaud O, Buffet M, Roman P, Plantier F, Dupin N. Study of persistence and recurrence rates in 106 patients with condyloma and intraepithelial neoplasia after CO2 laser treatment. Eur J Dermatol. 2008;18:153--8.
5.Knoll LD, Segura JW, Benson Jr RC, Goellner JR.阴茎肠状乳头状瘤:钕:YAG 激光治疗成功。J Urol.1988;139:1307--9.6.6. Colombel M, Pedron P, Missirlu A, Abbou C, Chopin D. 激光汽化阴道尖锐湿疣后的膀胱阴道瘘。J Urol.1995;154:1860.7.Tschanz C, Salomon D, Skaria A, Masouye I, Vecchietti GL, Harms M. CO2 激光治疗女性生殖器粘膜后的外阴炎。皮肤病学》。2001;202:371--2. 8.8. Savoca S, Nardo LG, Rosano TF, D'Agosta S, Nardo F. CO(2) 激光汽化作为人类乳头瘤病毒病变的主要治疗方法。前瞻性观察研究。Acta Obstet Gynecol Scand.2001;80:1121--4. 9.Lassus J, Happonen HP, Niemi KM, Ranki A. Carbon dioxide (CO2)-laser therapy cures macroscopic lesions, but viral genome is not eradicated in men with therapy-resistant HPV infection.Sex Transm Dis.1994;21:297--302.10.Aynaud O, Buffet M, Roman P, Plantier F, Dupin N. CO2 激光治疗后 106 例尖锐湿疣和上皮内瘤变患者的持续率和复发率研究。Eur J Dermatol.2008;18:153--8.
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引用次数: 0
Xanthoma disseminatum in a young man 一名年轻男子的散发性黄瘤
Pub Date : 2024-07-26 DOI: 10.25259/ijdvl_806_2024
A. Dev, Anish Thind, Purkshish Kaushal, Dipankar De, Kim Vaiphei
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引用次数: 0
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Indian Journal of Dermatology, Venereology and Leprology
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