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Should we use artificial intelligence (AI) for writing ICU diaries? Not yet! 我们应该使用人工智能(AI)来撰写重症监护室日记吗?还不需要!
IF 4.9 2区 医学 Q1 NURSING Pub Date : 2024-10-28 DOI: 10.1016/j.iccn.2024.103868
Ingrid Egerod
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引用次数: 0
Factors associated with the effectiveness of high-flow therapy in patients with acute hypoxemic respiratory failure: An observational study 急性低氧血症呼吸衰竭患者接受高流量治疗效果的相关因素:一项观察性研究。
IF 4.9 2区 医学 Q1 NURSING Pub Date : 2024-10-24 DOI: 10.1016/j.iccn.2024.103874
Annette Zevallos-Villegas , Jesus Gonzalez-Rubio , Fernando Neria Serrano , Berta Gallego-Rodriguez , Miguel Lorente-Gonzalez , Alberto Najera , Jose Rafael Teran-Tinedo , Juan D. Navarro-Lopez , Lydia Jimenez-Diaz , Pedro Landete

Backward

The COVID-19 pandemic has severely tested global health systems. Non-invasive respiratory support, especially combining high-flow nasal cannula (HFNC) and continuous positive airway pressure, has effectively treated COVID-19 induced Acute Hypoxemic Respiratory Failure and reduced mortality. However, HFNC alone is more comfortable, better tolerated, and less costly than non-invasive ventilation. Understanding which patients benefit from HFNC monotherapy versus combined therapies is essential.

Methods

This observational study included patients admitted to the intermediate respiratory care unit of a COVID-19 hospital between December 2020 and September 2021. All patients treated with HFNC were included (n = 1301). HFNC failure was defined as the need for escalated therapy (non-invasive ventilation, intubation) or death. Epidemiological, clinical, non-invasive respiratory support parameters, and laboratory data were collected, and a multivariable analysis identified key determinants.

Results

HFNC was successful in 39.9 % of patients. (n = 511) Risk factors for HFNC failure included increased age, male gender, obesity, obstructive sleep apnea, higher respiratory rate, initial SpO2/FiO2 ≤ 148, and initial PaO2/FiO2 ≤ 100. An increase in the ROX Index at 24 h and slower disease progression were associated with successful treatment. These findings led to the developmet of an index to identify patients who benefit most from HFNC monotherapy.

Conclusions

HFNC monotherapy can be effective for a specific profile of patients with Acute Hypoxemic Respiratory Failure due to COVID-19. This tool may help manage these patients more appropriately. Further studies are needed to determine if these findings can be applied to Acute Hypoxemic Respiratory Failure caused by other pathologies.

Implications for Clinical Practice

This study underscores the importance of early identification and management of patients at risk of HFNC failure in intermediate respiratory care units. By recognizing factors such as age, comorbidities, and respiratory indices, healthcare providers can implement targeted strategies to enhance HFNC success. These strategies may include more stringent monitoring, tailored respiratory support, and timely escalation to more intensive therapies if needed. Our findings highlight the need for a comprehensive approach to managing severe respiratory failure in critical care settings, ultimately improving patient outcomes and reducing the burden on healthcare systems.
落后:COVID-19 大流行严重考验了全球卫生系统。无创呼吸支持,特别是结合高流量鼻插管(HFNC)和持续气道正压,可有效治疗 COVID-19 引起的急性低氧血症呼吸衰竭并降低死亡率。然而,与无创通气相比,单独使用 HFNC 更舒适、耐受性更好、成本更低。了解哪些患者能从 HFNC 单药治疗和联合疗法中获益至关重要:这项观察性研究纳入了 2020 年 12 月至 2021 年 9 月期间入住 COVID-19 医院中级呼吸监护病房的患者。所有接受 HFNC 治疗的患者均纳入研究(n = 1301)。HFNC失败定义为需要升级治疗(无创通气、插管)或死亡。研究人员收集了流行病学、临床、无创呼吸支持参数和实验室数据,并通过多变量分析确定了关键的决定因素:结果:39.9%的患者 HFNC 成功。(n = 511)HFNC 失败的风险因素包括年龄增大、男性、肥胖、阻塞性睡眠呼吸暂停、呼吸频率较高、初始 SpO2/FiO2 ≤ 148 和初始 PaO2/FiO2 ≤ 100。24 小时后 ROX 指数的增加和疾病进展的减缓与治疗成功有关。这些发现促使我们开发了一种指数,用于识别从 HFNC 单一疗法中获益最多的患者:结论:HFNC 单一疗法对 COVID-19 导致的急性低氧血症呼吸衰竭患者的特定情况有效。该工具有助于更合理地管理这些患者。我们还需要进一步研究,以确定这些发现是否适用于由其他病症引起的急性低氧血症性呼吸衰竭:本研究强调了中级呼吸监护病房早期识别和管理有 HFNC 功能衰竭风险的患者的重要性。通过识别年龄、合并症和呼吸指数等因素,医疗服务提供者可以实施有针对性的策略,以提高 HFNC 的成功率。这些策略可能包括更严格的监测、量身定制的呼吸支持,以及在必要时及时升级到更强化的疗法。我们的研究结果凸显了在重症监护环境中采用综合方法管理严重呼吸衰竭的必要性,最终可改善患者的预后并减轻医疗系统的负担。
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引用次数: 0
Symptom management of thirst for seriously ill and dying patients in critical care 危重病人和垂危病人口渴时的症状处理。
IF 4.9 2区 医学 Q1 NURSING Pub Date : 2024-10-23 DOI: 10.1016/j.iccn.2024.103869
Natalie Pattison
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引用次数: 0
Treatment futility: Continuation or withdrawal of life-sustaining treatment in intensive care units 治疗无效:在重症监护室继续或撤消维持生命的治疗。
IF 4.9 2区 医学 Q1 NURSING Pub Date : 2024-10-22 DOI: 10.1016/j.iccn.2024.103813
Hye Ri Choi , Mu-Hsing Ho , Chia-Chin Lin
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引用次数: 0
Do we still need to talk about antimicrobial resistance? 我们还需要讨论抗菌药耐药性吗?
IF 4.9 2区 医学 Q1 NURSING Pub Date : 2024-10-21 DOI: 10.1016/j.iccn.2024.103860
Jean-Ralph Zahar, Pierre Moenne-Locoz
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引用次数: 0
A guide to the guidelines: Closing the gap from practice guidelines to quality of care improvement in ventilator-associated pneumonia 指南指南:缩小从实践指南到呼吸机相关肺炎护理质量改进之间的差距。
IF 4.9 2区 医学 Q1 NURSING Pub Date : 2024-10-21 DOI: 10.1016/j.iccn.2024.103870
Guillaume Millot, Gregoire Demont, Saad Nseir
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引用次数: 0
Non-timely and incomplete carbapenem infusions: A plea to include administration practices as a key element in antimicrobial stewardship 卡巴培南输注不及时和不完全:呼吁将管理方法作为抗菌药物管理的关键要素。
IF 4.9 2区 医学 Q1 NURSING Pub Date : 2024-10-21 DOI: 10.1016/j.iccn.2024.103872
Dorian Vanneste, Hendrik Bracht, Isabel Spriet
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引用次数: 0
Validity and reliability of the Endotracheal Suction Assessment Tool© in adult ICU patients: A methodological study 成人重症监护病房患者气管内吸入评估工具©的有效性和可靠性:方法学研究。
IF 4.9 2区 医学 Q1 NURSING Pub Date : 2024-10-19 DOI: 10.1016/j.iccn.2024.103862
İlkin Yılmaz , Zilan Baran

Background

Novice nurses often find endotracheal suctioning signs unfamiliar. The Endotracheal Suction Assessment Tool© (ESAT©) aids pediatric nurses in suctioning but lacks an adult equivalent. A valid and reliable ESAT© for assessing intensive care unit patients’ suction needs across different populations is necessary.

Aim

To test the validity and reliability of the ESAT© in adult ICU patients.

Methods

This methodological study assessed suction needs in patients at a tertiary adult ICU of a university hospital. Two independent observers used the ESAT© to determine suction needs. Data from 106 suction procedures were collected using a patient characteristics form, the ESAT©, and a suction monitoring form. The ESAT© includes eight respiratory and ventilation parameters and seven clinical consideration parameters. Hemodynamic and respiratory parameters were measured before, and one and five minutes after suction. Linguistic validity, content validity, and pilot testing were conducted. Interobserver agreement was evaluated, and psychometric evaluation was done using content validity index (CVI) and intraclass correlation coefficient (ICC). Data were analyzed with paired samples t-test and ANOVA.

Results

Item CVI ranged from 0.80 to 1.00, and scale CVI was 0.96. Inter-item correlation and ICC for inter-rater reliability were both 0.933 (95 % CI = 0.903–0.954, p < 0.001 for ICC). Cohen’s Kappa coefficients ranged from 0.690 to 1.000 (p < 0.001), indicating high consistency between raters for all tool items. All scale items showed near-perfect agreement except SpO2, which showed substantial agreement.

Conclusion

The S-CVI was good, indicating near-perfect agreement among raters. ESAT© is highly reliable and valid for determining suction needs in adult intensive care patients.

Implications for Practice

The ESAT© aids autonomous decision-making for suctioning needs. Originally for novice pediatric nurses, the ESAT© was adapted for adult intensive care nurses. The ESAT© is valid and reliable for adult intensive care patients.
背景:新手护士往往对气管内吸引的体征感到陌生。气管内吸引评估工具©(ESAT©)可帮助儿科护士进行吸引,但缺乏与之对应的成人工具。目的:测试 ESAT©在成人 ICU 患者中的有效性和可靠性:这项方法学研究评估了一家大学医院三级成人重症监护病房患者的吸痰需求。两名独立观察员使用 ESAT© 确定吸痰需求。研究人员使用患者特征表、ESAT© 和吸痰监测表收集了 106 例吸痰过程的数据。ESAT© 包括八个呼吸和通气参数以及七个临床考虑参数。在吸痰前、吸痰后 1 分钟和 5 分钟测量血液动力学和呼吸参数。进行了语言有效性、内容有效性和试点测试。对观察者之间的一致性进行了评估,并使用内容效度指数(CVI)和类内相关系数(ICC)进行了心理测量学评估。数据采用配对样本 t 检验和方差分析:项目 CVI 为 0.80 至 1.00,量表 CVI 为 0.96。项目间相关性和评分者间可靠性的 ICC 均为 0.933(95 % CI = 0.903-0.954,p 结论:S-CVI 良好,表明评分者间可靠性的 ICC 为 0.933(95 % CI = 0.903-0.954,p 结论):S-CVI 结果良好,表明评分者之间的一致性接近完美。ESAT© 在确定成人重症监护患者的吸痰需求方面具有高度可靠性和有效性:ESAT©有助于自主决定吸痰需求。ESAT© 最初是为儿科新手护士设计的,后被成人重症监护护士所采用。ESAT© 对成人重症监护患者有效且可靠。
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引用次数: 0
Effects of Wab-WPPEP on post-intensive care syndrome-family in family caregivers of heart valve replacement patients: A randomized controlled trial Wab-WPPEP 对心脏瓣膜置换术患者家庭护理人员重症监护后综合征的影响:随机对照试验
IF 4.9 2区 医学 Q1 NURSING Pub Date : 2024-10-18 DOI: 10.1016/j.iccn.2024.103817
Jing Xiong , Ting-Ting Wu , Hong Cai , Jin-Yi He , Tang-Ying Wang , Xiu-Xia Lin , Hong Li

Objectives

To evaluate the effects of a WeChat applet-based whole process psychological empowerment program (Wab-WPPEP) on post-intensive care syndrome-family in family caregivers of heart valve replacement patients.

Design

Two-arm, parallel, randomized controlled clinical trial.

Settings

A tertiary general hospital in Fuzhou, China.

Methods

Participants were randomly assigned to two groups. The intervention group received Wab-WPPEP, while the control group received routine care. The intervention was implemented from ICU admission to one month post-discharge. The primary outcome was anxiety, while secondary outcomes included depression, post-traumatic stress disorder (PTSD), and quality of life. Outcomes were assessed at baseline (T0), before ICU transfer (T1), pre-discharge (T2), and one month post-discharge (T3) using standardized questionnaires. Generalized estimating equations were used to analyze the repeated-measures data.

Results

The intervention group exhibited greater improvements in anxiety (T1: β = −1.92, 95 % CI: −2.35 to −1.49, P < 0.001; T2: β = −1.66, 95 % CI: −2.03 to −1.29, P < 0.001; T3: β = −3.98, 95 % CI: −4.34 to −3.62, P < 0.001), depression (T1: β = −1.32, 95 % CI: −1.79 to −0.85, P < 0.001; T2: β = −1.70, 95 % CI: −2.08 to −1.32, P < 0.001), and quality of life (T2: β = 31.16, 95 % CI: 21.35 to 40.98, P < 0.001) compared to the routine-care group. PTSD scores were also significantly lower in the intervention group (t = −6.454, P < 0.001).

Conclusions

Wab-WPPEP significantly reduced anxiety and depression, improved quality of life, and alleviated PTSD symptoms in family caregivers of heart valve replacement patients.

Implications for clinical practice

Comprehensive psychological interventions should be implemented throughout the ICU stay and recovery period to improve family caregiver well-being.
目的评估基于微信小程序的全过程心理赋权项目(Wab-WPPEP)对心脏瓣膜置换术后患者家庭护理人员重症监护后综合征-家庭的影响:双臂、平行、随机对照临床试验:方法:将参与者随机分为两组:方法:参与者被随机分配到两组。干预组接受 Wab-WPPEP,对照组接受常规护理。干预措施从重症监护室入院到出院后一个月内实施。主要结果是焦虑,次要结果包括抑郁、创伤后应激障碍(PTSD)和生活质量。采用标准化问卷对基线(T0)、转入 ICU 前(T1)、出院前(T2)和出院后一个月(T3)的结果进行评估。采用广义估计方程分析重复测量数据:结果:干预组在焦虑方面有更大的改善(T1:β =-1.92,95 % CI:-2.35 至-1.49,P 结论:Wab-WPPEP 显著降低了患者的焦虑:Wab-WPPEP能明显减轻心脏瓣膜置换术患者家属照顾者的焦虑和抑郁,提高生活质量,减轻创伤后应激障碍症状:临床实践的启示:应在重症监护室住院和康复期间实施全面的心理干预措施,以改善家庭护理人员的福祉。
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引用次数: 0
Simulated haemodynamic parameters and different infusion set-up affect drug delivery during syringe pump change over: A bench-top study in a laboratory setting 模拟血流动力学参数和不同的输液设置会影响注射泵切换时的药物输送:实验室环境下的台式研究
IF 4.9 2区 医学 Q1 NURSING Pub Date : 2024-10-17 DOI: 10.1016/j.iccn.2024.103861
Alberto Lucchini , Stefano Elli , Alessia Burgazzi , Laura Malvestuto Grilli , Claudia Pes , Katia Ferrari , Letizia Fumagalli , Chiara Fiorillo , Marco Giani , Emanuele Rezoagli

Background

Infusion therapy is widely used in clinical settings, particularly in intensive care units.

Aim

to explore the influence of simulated cardiac output on “bolus” or “backflow” events that can occur during syringe pump changeover, considering several factors that have been previously outlined in published research. Syringe infusion pumps are commonly used for precise continuous intravenous drug delivery. Syringe pump changeover can be a challenging procedure.

Methods

Bench-top study in a laboratory setting. An extracorporeal circuit was used to simulate a cardiac output of 5 l/min. The following variables were used: three levels of vertical position of the syringe pump (−50 cm, 0, +50 cm), three levels of Central Venous Pressure (−5, 10, and 15 mmHg), presence/absence of carrier infusion (5 ml/h), and presence/absence of a needle-free connector between the syringe and extension line.

Results

A total of 108 syringe pump changes were performed with different combinations of the investigated variables. The mean time for syringe pump changeover was equal to 9.48 ± 2.45 s and the overall fluid displacement was 8 ± 40 µL (microlitres) (range, −262–156 µL). The CVP level and vertical position of the pump always statistically affected the overall displacement during syringe pump changeover. When a second infusion with an equal velocity rate to that of a syringe pump infusion is present in the same lumen, the presence of a needle-free device reduces the overall volume of displacement.

Conclusions

Syringe pump changeover can be a critical moment for patients when vasoactive drugs are administered.

Implications for clinical practice

In a simulated environment with a cardiac output of 5 L/min, the CVP level and vertical position of the syringe pump generated bolus or backflow events during the syringe pump changeover. The application of carrier infusion appeared to intensify these phenomena. Employing a neutral, needle-free system can potentially aid in reducing the development of boluses or backflows.
背景输液治疗广泛应用于临床环境,尤其是重症监护病房。目的探讨模拟心输出量对注射泵转换过程中可能发生的 "栓剂 "或 "回流 "事件的影响,同时考虑之前发表的研究中概述的几个因素。注射器输液泵通常用于精确连续的静脉给药。注射泵的更换可能是一个具有挑战性的过程。使用体外循环模拟 5 升/分钟的心输出量。使用了以下变量:注射泵的三个垂直位置(-50 厘米、0、+50 厘米)、三个中心静脉压(-5、10 和 15 毫米汞柱)、有无载体输注(5 毫升/小时)以及注射器和延长管之间有无无针连接器。注射泵切换的平均时间为 9.48±2.45 秒,总液体排量为 8 ± 40 µL(微升)(范围为 -262-156 µL)。在注射泵转换过程中,CVP 水平和泵的垂直位置始终对总排量有统计学影响。在心输出量为 5 升/分钟的模拟环境中,CVP 水平和注射泵的垂直位置会在注射泵转换期间产生栓塞或回流事件。应用载体输注似乎会加剧这些现象。采用中性无针系统可能有助于减少栓塞或回流的发生。
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引用次数: 0
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Intensive and Critical Care Nursing
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