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Influence of Alcohol Dependence on the Clinical and Dynamic Characteristics of Bipolar Disorder with Their Comorbidity in Psychiatric Hospital Patients 酒精依赖对精神病院患者双相情感障碍及其并发症的临床和动态特征的影响
Pub Date : 2024-01-03 DOI: 10.30629/2618-6667-2023-21-6-42-49
S. N. Vasilieva, G. Simutkin, E. D. Schastnyy, E. V. Lebedeva, N. Bokhan
   Background: numerous studies indicate a high level of comorbidity of bipolar disorder with other psychiatric disorders. Alcohol dependence is one of the most common comorbid pathologies, along with anxiety disorders and personality disorders.   Objective: determination of the frequency of comorbidity of BAR with alcohol dependence in patients of a specialized psychiatric hospital and identiашcation of clinical and dynamic features of BAR with this comorbidity.   Patients and methods: in the psychiatric unit, 188 patients with bipolar disorder diagnosed according to ICD-10 (136 women and 52 men) were examined. The age of female patients was 41.6 ± 14.4 years, male — 39.4 ± 14.0 years. Depending on the current affective disorder, patients were distributed as follows: a depressive episode — 62.2 % (n = 117), a hypomanic episode — 2.7 % (n = 5), a manic episode (ME) — 1.6 % (n = 3), mixed episode — 33.5 % (n = 63). A comparative assessment of the clinical and dynamic characteristics of bipolar disorder was carried out in 2 groups of patients: with bipolar disorder and comorbid alcohol dependence — 30 individuals (14 women and 16 men), aged 43 years [29; 55] and without comorbidity with alcohol dependence — 59 individuals (39 women and 20 men), age 36 years [29; 50]. During the study, clinical-psychopathological, clinical-catamnestic, psychometric, statistical methods were used.   Results and discussion: the level of comorbidity of bipolar disorder with alcohol dependence was determined — 15.9 %. It was found that in BD with comorbid alcohol dependence, compared with BD without alcohol dependence, patients have an early onset age of BD, more often have mixed episodes during an affective disorder. In addition, such patients have a higher risk of suicidal behavior, bipolar-I, and exacerbation of affective symptoms. It has also been shown that alcohol dependence makes it difficult to recognize bipolar disorder during the primary visit to specialized psychiatric care.   Conclusion: addition of alcohol dependence to bipolar disorder affects negatively its main clinical and dynamic parameters and delays the terms of its diagnostics.
背景:大量研究表明,双相情感障碍与其他精神疾病的并发率很高。酒精依赖是最常见的合并病症之一,此外还有焦虑症和人格障碍。 目的:确定一家精神病专科医院的躁狂症患者合并酒精依赖症的频率,并识别合并酒精依赖症的躁狂症患者的临床和动态特征。 患者和方法:在该精神病院,188 名根据 ICD-10 诊断的躁郁症患者(136 名女性和 52 名男性)接受了检查。女性患者的年龄为 41.6 ± 14.4 岁,男性患者的年龄为 39.4 ± 14.0 岁。根据当前的情感障碍,患者的分布情况如下:抑郁发作 - 62.2 %(n = 117),躁狂发作 - 2.7 %(n = 5),躁狂发作 (ME) - 1.6 %(n = 3),混合发作 - 33.5 %(n = 63)。在两组患者中对躁狂症的临床和动态特征进行了比较评估:有躁狂症和合并酒精依赖症的患者--30 人(14 名女性和 16 名男性),年龄 43 岁 [29; 55];没有合并酒精依赖症的患者--59 人(39 名女性和 20 名男性),年龄 36 岁 [29; 50]。研究过程中使用了临床-心理病理学、临床-统计、心理测量和统计方法。 结果与讨论:双相情感障碍与酒精依赖的合并率为 15.9%。研究发现,与不伴有酒精依赖的双相情感障碍患者相比,伴有酒精依赖的双相情感障碍患者发病年龄较早,在情感障碍期间更经常出现混合发作。此外,这类患者出现自杀行为、躁郁Ⅰ和情感症状加重的风险更高。研究还表明,酒精依赖会使躁狂症患者在初诊时很难被专门的精神科医生识别。 结论:在躁郁症中加入酒精依赖会对其主要的临床和动态参数产生负面影响,延误诊断。
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引用次数: 0
The Phenomenon of God’s Abandonment in Clinical Psychiatry 临床精神病学中的上帝遗弃现象
Pub Date : 2024-01-02 DOI: 10.30629/2618-6667-2023-21-6-17-30
A. G. Alekseeva, T. Vladimirova, E. Gedevani, G. Kopeyko, O. Borisova
   Background: God’s abandonment in religious literature is defined as the loss of divine grace, the feeling of distance from God, abandonment by God, God’s departure from man, which is manifested in the weakening of divine support, often perceived as a period of spiritual crisis and accompanied by despair and heartache. At present, there are lack of a psychopathological andclinical studies in the scientiашc literature concerning the phenomenon of God’s abandonment. This phenomenon is complex and little studied neither in the spiritual life nor in the context of clinical psychiatry. The phenomenon of God’s abandonment requires further research for proper diagnosis, choice of the correct treatment, psychotherapeutic support, and adequate tacticsof pastoral care.   Objectives: identification of clinical and psychopathological features and structure of the phenomenon of God’s abandonment in order to determine the syndromal and nosological affiliation, prognosis issues and right choice of therapeutic tactics.   Patients and methods: 35 patients (16 male and 19 female) aged 18–55 years (mean 39.8 ± 11.6), who had a sense of God’s abandonment in the clinical picture of endogenous depression and depression-delusional disorders, were examined. Clinical-psychopathologic, psychometric (HDRS, CRS, SAG) and statistical methods were used. As a control group, 5 male individuals who were monastic residents and were not in the psychiatrist’s ашeld of vision and not demonstrated obvious signs of psychiatricdisorders were examined. For this group, a retrospective analysis of the peculiarities of the phenomenon of God’s abandonment was carried out on the basis of the assessment of subjective and objective data.   Results: the conducted research has revealed that the phenomenon of God’s abandonment is a special psychopathological symptom complex specific for the studied group of patients, regardless the syndromal or nosological affiliation. The main manifestation of this phenomenon is the religiousanesthesia (as the religious equivalent of anaesthesia psychica dolorosa) with the leading manifestations of the absence of sensations of religious feeling with the key experience of abandonment by God in close link with the other psychopathological disorders. Three types of conditions with the phenomenon of God’s abandonment have been identiашed: type 1 — depressions with the phenomenon of God’s abandonment and manifestations of affective delusion (22 patients, 62 %; 12 men, 10 women; mean age 43.4 ± 11.2 years) in the structure of affective psychosis; type 2 — acute psychotic states with the phenomenon of God’s abandonment and noncongruent delusional disorders (13 patients, 37 %; 4 men, 9 women; mean age 31.7 ± 8.2 years) in the structure of schizoaffective disorder or schizophrenia spectrum; type 3 — crisis of faith (5 men from the control group; mean age 40 ± 11.8 years) which is the psychological crisis with experience of God’s abandonment within the framework of pers
背景:神的遗弃在宗教文献中被定义为神恩的丧失、与神的距离感、被神遗弃、神离开人,表现为神的支持减弱,通常被视为精神危机时期,并伴随着绝望和心痛。目前,科学文献中缺乏关于上帝遗弃现象的心理病理学和临床研究。这种现象非常复杂,无论是在精神生活中还是在临床精神病学中都鲜有研究。上帝遗弃现象需要进一步的研究,以便进行正确的诊断、选择正确的治疗方法、提供心理治疗支持以及采取适当的教牧关怀策略。 目的:确定 "上帝遗弃 "现象的临床和心理病理学特征及结构,以确定综合征和疾病分类、预后问题以及治疗策略的正确选择。 患者和方法:研究对象为 35 名患者(男 16 名,女 19 名),年龄在 18-55 岁之间(平均 39.8 ± 11.6),他们在内源性抑郁症和抑郁妄想症的临床表现中都有被上帝遗弃的感觉。研究采用了临床心理病理学、心理测量(HDRS、CRS、SAG)和统计学方法。作为对照组,对 5 名男性进行了研究,他们都是寺院住持,不在精神科医生的视线范围内,也没有表现出明显的精神障碍症状。在对主观和客观数据进行评估的基础上,对这一群体的 "上帝遗弃 "现象的特殊性进行了回顾性分析。 结果:研究结果表明,"上帝遗弃 "现象是所研究的这组病人特有的一种特殊精神病理症状综合体,与综合症或疾病分类无关。这种现象的主要表现是宗教性失神(相当于宗教性失神),其主要表现是宗教感缺失,主要体验是被上帝遗弃,与其他精神病理障碍密切相关。目前已确定三种具有上帝遗弃现象的病症类型:类型 1--具有上帝遗弃现象和情感妄想表现的抑郁症(22 名患者,占 62%;12 名男性,10 名女性;平均年龄为 43.4 ± 11.2 岁),属于情感性精神病;类型 2--具有上帝遗弃现象和非一致性妄想障碍的急性精神病状态(13 名患者,占 37%;4 名男性,9 名女性;平均年龄为 31.7 ± 8.2 岁),属于情感性精神病;类型 3--具有上帝遗弃现象和非一致性妄想障碍的急性精神病状态(13 名患者,占 37%;4 名男性,9 名女性;平均年龄为 31.7 ± 8.2 岁),属于情感性精神病。7±8.2岁);3型--信仰危机(对照组5名男性;平均年龄40±11.8岁),即在个人发展框架内经历上帝遗弃的心理危机。 结论:"上帝遗弃 "现象可以代表一系列心理和精神病理学状况:从精神心理危机到各种精神疾病:高估观念、麻醉性和人格解体性非精神病性抑郁症、妄想性抑郁症或急性精神病。与上帝遗弃现象相一致的状态类型具有不同的诊断价值。
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引用次数: 0
Cross-Cohort Changes in Parent-Rated Child Mental Health over Two Decades 二十年来家长对儿童心理健康评价的跨队列变化
Pub Date : 2024-01-02 DOI: 10.30629/2618-6667-2023-21-6-6-16
H. R. Slobodskaya, O. S. Kornienko, I. Leto, T. Ryabichenko, A. Varshal, E. N. Petrenko, E. A. Kozlova, M. E. Grishkevich, S. Loginova
   Background: research on time trends in child mental health is needed to clarify the effects of the COVID-19 pandemic, and to predict later developmental pathways. However, the results obtained in different countries may be relatively culture specific.   The aim was to compare levels of child mental health in three comparable cohorts assessed with identical measures before and during the COVID-19 pandemic, taking age, gender and family sociodemographic characteristics into account.   Participants and methods:: three cohorts of 2–14-year-old children from a large Siberian city were compared: 1436 (52 % boys) assessed in 2001–2004, 1508 (49 % boys) assessed in 2014–2017 and 1276 (52 % boys) assessed in 2020–2021. Parents completed the Strengths and Difficulties Questionnaire designed for a quantitative assessment of child and adolescent psychiatric problems and prosocial behaviour. Linear regression analyses examined cross-cohort changes by age and gender controlling for family composition, parental education and occupation.   Results: from 2001 to 2021, levels of child psychiatric problems and their impact on daily functioning decreased, whereas levels of prosocial behaviour increased. During the COVID-19 pandemic, there was an increase in levels of emotional symptoms and conduct problems and a decrease in levels of prosocial behaviour compared to the prepandemic period. Time trends in child mental health were similar for both boys and girls of different ages and did not depend on family composition or parental education and occupation.   Conclusions: over 20 years, there were positive trends in child mental health; however, psychosocial stress during the pandemic was accompanied by negative changes. Further studies will need to clarify possible determinants of secular trends in Russian child mental health and different developmental pathways.
背景:需要对儿童心理健康的时间趋势进行研究,以明确 COVID-19 大流行的影响,并预测以后的发展路径。然而,在不同国家获得的结果可能相对具有文化特异性。 我们的目的是比较 COVID-19 大流行之前和期间三个具有可比性的队列中使用相同方法评估的儿童心理健康水平,同时考虑年龄、性别和家庭社会人口特征。 参与者和方法:比较了来自西伯利亚一个大城市的三组 2-14 岁儿童:2001-2004年评估了1436名儿童(52%为男孩),2014-2017年评估了1508名儿童(49%为男孩),2020-2021年评估了1276名儿童(52%为男孩)。家长填写了 "优势与困难问卷",该问卷旨在对儿童和青少年的精神问题以及亲社会行为进行量化评估。线性回归分析研究了不同年龄和性别组群之间的变化,并对家庭组成、父母教育程度和职业进行了控制。 结果表明:从 2001 年到 2021 年,儿童精神问题的程度及其对日常功能的影响有所下降,而亲社会行为的程度则有所上升。在 COVID-19 大流行期间,与大流行前相比,情绪症状和行为问题的水平有所上升,而亲社会行为的水平有所下降。不同年龄段的男孩和女孩在儿童心理健康方面的时间趋势相似,并且与家庭组成或父母的教育和职业无关。 结论:20 年来,儿童心理健康呈现出积极的趋势;然而,大流行期间的社会心理压力伴随着消极的变化。进一步的研究需要澄清俄罗斯儿童心理健康长期趋势的可能决定因素和不同的发展途径。
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