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The Role of Confirmatory Testing in Carpal Tunnel Syndrome: Electrodiagnostic Study, Ultrasound and CTS-6. 腕管综合征确诊测试的作用:电诊断研究、超声波和 CTS-6。
IF 0.5 Q4 SURGERY Pub Date : 2025-02-01 Epub Date: 2024-10-08 DOI: 10.1142/S2424835525400016
Daniel C Gabriel, Leah Demetri, Dafang Zhang

Carpal tunnel syndrome (CTS) is the most common upper extremity compressive neuropathy. The reference standard for the diagnosis of CTS remains an area of controversy. The diagnosis can be established clinically, but options for confirmatory testing include electrodiagnostic studies, ultrasound and diagnostic aids such as the CTS-6 score. This review article summarises the current evidence for each confirmatory testing modality, contrasts their advantages and disadvantages and discusses future directions for investigation. Level of Evidence: Level V (Diagnostic).

腕管综合征(CTS)是最常见的上肢压迫性神经病。诊断 CTS 的参考标准仍存在争议。诊断可以通过临床确定,但确诊测试的选择包括电诊断研究、超声波和诊断辅助工具(如 CTS-6 评分)。这篇综述文章总结了每种确诊检测方式的现有证据,对比了它们的优缺点,并讨论了未来的研究方向。证据等级:五级(诊断)。
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引用次数: 0
Making an Impact. 产生影响。
IF 0.5 Q4 SURGERY Pub Date : 2025-02-01 Epub Date: 2025-01-10 DOI: 10.1142/S2424835525010015
S Raja Sabapathy
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引用次数: 0
A 7-Year Retrospective Review of Flexor Sheath Infections. 屈指鞘感染七年回顾性研究
IF 0.5 Q4 SURGERY Pub Date : 2025-02-01 Epub Date: 2024-10-14 DOI: 10.1142/S2424835525500080
Harjoat Riyat, Holly Morris, Caroline Cheadle, Amanda Leatherbarrow, Dupinderjit Singh Rae, Nick Johnson

Background: Flexor sheath infections require prompt diagnosis, and management with intravenous antibiotics and/or surgical washout followed by hand therapy. Complication rates as high as 38% have been reported. Our unit takes a relatively conservative approach to the management of flexor sheath infections and select patients are managed non-surgically via our outpatient antibiotic service where they are clinically reviewed and receive a once daily dose of intravenous antibiotics. The aim of this study is to determine if outpatient management of flexor sheath infections was associated with an increased risk of complications compared to those admitted as an inpatient. Methods: A retrospective review was carried out with all patients clinically diagnosed with flexor sheath infection who were seen at our unit between January 2014 and December 2020. Age, gender, co-morbidities, cause of infection, management and subsequent complications were recorded. Results: A total of 128 patients with flexor sheath infections were treated. And 68% were male. Mean age was 50.4 years. A trend towards fewer presentations each year with animal bites, foreign bodies and penetrating trauma as the main cause of infection was noted. And 89% (n = 114) required admission with the other 11% (n = 14) treated as an outpatient. And 77% (n = 98) underwent surgical washout. And 6% (n = 8) suffered a complication. Conclusions: While flexor sheath washout continues to be standard practice, 23% of patients were safely managed with intravenous antibiotics and 11% purely via an outpatient service. Level of Evidence: Level IV (Therapeutic).

背景:屈指鞘感染需要及时诊断,并通过静脉注射抗生素和/或手术冲洗进行治疗,然后进行手部治疗。据报道,并发症发生率高达 38%。我们科室对屈指鞘感染采取相对保守的治疗方法,并通过门诊抗生素服务对部分患者进行非手术治疗,对他们进行临床复查,并每天一次静脉注射抗生素。本研究的目的是确定与住院病人相比,门诊治疗屈指鞘感染是否会增加并发症风险。研究方法对 2014 年 1 月至 2020 年 12 月期间在本单位就诊的所有临床诊断为屈侧鞘感染的患者进行回顾性分析。记录了患者的年龄、性别、合并疾病、感染原因、治疗方法和后续并发症。结果:共治疗了128名屈腱鞘感染患者。68%为男性。平均年龄为 50.4 岁。感染的主要原因是动物咬伤、异物和穿透性创伤。89%的患者(114人)需要入院治疗,另外11%的患者(14人)需要门诊治疗。77%(98 人)接受了手术冲洗。6%(8 人)出现并发症。结论:虽然挠曲鞘冲洗仍是标准做法,但23%的患者通过静脉注射抗生素得到了安全治疗,11%的患者纯粹通过门诊服务得到了治疗。证据等级:IV级(治疗)。
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引用次数: 0
An Updated Survey of Trends in the Surgical Management of Thumb Carpometacarpal Arthritis - The Increasing Popularity of the Suture Suspension Arthroplasty. 拇指腕掌关节炎手术治疗趋势的最新调查--缝合悬吊关节成形术日益流行。
IF 0.5 Q4 SURGERY Pub Date : 2025-02-01 Epub Date: 2024-10-14 DOI: 10.1142/S2424835525500079
William L Wang, William H E Neal, S Steven Yang

Background: The purpose of this study was to conduct an updated survey of American Society for Surgery of the Hand (ASSH) membership to evaluate current preferences for surgical management of thumb CMC arthritis. Past surveys have demonstrated LRTI to be the most preferred surgical technique. We hypothesised that current surgical preferences for thumb CMC arthritis have changed over the last several years due to rising popularity of high-strength suture implants. Methods: A 22-question survey inquired about the preferences for the surgical management of basal joint arthritis and was sent to the ASSH membership. Descriptive statistics were calculated on all survey questions. Chi-squared analysis was used to compare differences in thumb CMC arthroplasty preferences across respondents. Results: A total of 1,499 responses were available for analysis, yielding a response rate of 29.9%. For surgical management of basal joint arthritis in the primary setting, the largest percentage of respondents preferred open trapeziectomy with suture suspension arthroplasty (39.2%); amongst them, over half (56%) used a high-strength suture implant. This was followed by open trapeziectomy with LRTI (38.3%). In the revision setting, most respondents preferred open trapeziectomy with suture suspension arthroplasty (53.5%), followed by LRTI (24.6%). In determining the choice of procedure, respondents felt some form of metacarpal suspension and implant cost to be more important factors than ligament reconstruction and interposition. A higher proportion of international members (16.2%) utilised implant arthroplasty than US/Canadian members (1.1%; p < 0.01). Conclusions: Past surveys have demonstrated LRTI to be the most preferred surgical technique. The current survey demonstrates open trapeziectomy and suture suspension arthroplasty, especially using high-strength suture implants, gaining popularity amongst surgeons, while open trapeziectomy and LRTI decreasing in preference. Suture suspension arthroplasty is now the preferred surgical technique in both the primary and revision setting. Level of Evidence: Level IV (Therapeutic).

背景:本研究的目的是对美国手外科学会(ASSH)会员进行一项最新调查,以评估目前对拇指 CMC 关节炎手术治疗的偏好。过去的调查显示,LRTI 是最受欢迎的手术技术。我们假设,在过去几年中,由于高强度缝合植入物越来越受欢迎,目前对拇指 CMC 关节炎手术治疗的偏好发生了变化。调查方法向 ASSH 会员发送了一份包含 22 个问题的调查问卷,询问他们对基底关节关节炎手术治疗的偏好。对所有调查问题进行了描述性统计。采用卡方分析比较不同受访者对拇指 CMC 关节置换术偏好的差异。结果:共有 1,499 份回复可供分析,回复率为 29.9%。对于基底关节关节炎的初级手术治疗,最大比例的受访者(39.2%)倾向于开放式梯形切除术加缝合悬吊关节成形术;其中,超过一半(56%)的受访者使用高强度缝合植入物。其次是开放式梯形切除术加 LRTI(38.3%)。在翻修手术中,大多数受访者首选开放式梯形切除术加缝合悬吊关节成形术(53.5%),其次是 LRTI(24.6%)。在决定选择哪种手术时,受访者认为某种形式的掌骨悬吊和植入成本是比韧带重建和内固定更重要的因素。使用植入关节成形术的国际会员比例(16.2%)高于美国/加拿大会员(1.1%;P 结论:过去的调查显示,LRTI 是最受欢迎的手术技术。目前的调查显示,开放式梯形切除术和缝合悬吊关节成形术,尤其是使用高强度缝合植入物,在外科医生中越来越受欢迎,而开放式梯形切除术和 LRTI 的受欢迎程度则有所下降。缝合悬吊关节置换术目前在初次手术和翻修手术中都是首选的手术技术。证据等级:四级(治疗)。
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引用次数: 0
The Use of Cone-Beam Computed Tomography (CBCT) Arthrography for Wrist Ligamentous Injuries - A Diagnostic Test Accuracy Meta-analysis. 使用锥形束计算机断层扫描(CBCT)关节造影术治疗腕部韧带损伤--诊断测试准确性 Meta 分析。
IF 0.5 Q4 SURGERY Pub Date : 2025-02-01 Epub Date: 2024-10-14 DOI: 10.1142/S2424835525500067
Harnoor-Khroud Dhillon, Djamila M Rojoa, Zaid Raheman, Nicholas Cereceda Monteoliva, Govind Dhillon, Firas J Raheman

Background: Diagnosis of ligamentous wrist injuries can be challenging with the absence of dynamic instability on radiographs. Our aim was to evaluate the accuracy of cone-beam computed tomography (CBCT) arthrography in diagnosing scapholunate ligament (SLL), lunotriquetral ligament (LTL) and triangular fibrocartilage complex (TFCC) injuries. Methods: A systematic review and literature search were conducted in compliance with Preferred Reporting Items for a Systematic Review and Meta-analysis (PRISMA) and registered at the International Prospective Register of Systematic Reviews, PROSPERO (CRD42024517655). A mixed-effects logistic regression bivariate model was used to estimate summary sensitivity and specificity, and hierarchical summary receiver operating characteristic (HSROC) curves were constructed to determine diagnostic accuracy of CBCT arthrography. Results: We identified five studies assessing the accuracy of CBCT arthrography against wrist arthrography or intraoperative findings as reference standard. The pooled estimates for sensitivity and specificity of CBCT arthrography was 93% (95% CI 40-100) and 91% (95% CI 81-96) for SLL injuries, 83% (95% CI 37-98) and 64% (95% CI 42-81) for LTL injuries and 78% (95% CI 57-91) and 80% (95% CI 54-93) for TFCC injuries. The area under the curve was 0.91 (95% CI 0.89-0.94), showing an excellent diagnostic accuracy of CBCT arthrography in SLL injuries. CBCT arthrography had an estimated mean effective dose of 3.2 mSv (2.0-4.8). Conclusions: Our study confirms that CBCT arthrography has an excellent diagnostic accuracy for wrist ligamentous injuries with comparably high sensitivity to conventional arthrography and a better specificity. While further studies with more robust methodology are required to support its implementation in clinical practice, our analysis shows that it is a reliable option and has a promising future. Level of Evidence: Level III (Diagnostic).

背景:腕部韧带损伤的诊断具有挑战性,因为在X光片上没有动态不稳定性。我们的目的是评估锥形束计算机断层扫描(CBCT)关节造影术诊断肩胛韧带(SLL)、月锁韧带(LTL)和三角纤维软骨复合体(TFCC)损伤的准确性。方法:按照系统综述和元分析的首选报告项目(PRISMA)进行了系统综述和文献检索,并在国际系统综述前瞻性注册中心 PROSPERO 注册(CRD42024517655)。该研究采用混合效应逻辑回归双变量模型来估算灵敏度和特异度,并构建了分层总结接收者操作特征曲线(HSROC)来确定CBCT关节造影的诊断准确性。结果:我们发现有五项研究评估了 CBCT 关节造影与腕关节造影或术中发现作为参考标准的准确性。CBCT关节造影对SLL损伤的敏感性和特异性的汇总估计分别为93%(95% CI 40-100)和91%(95% CI 81-96),对LTL损伤的敏感性和特异性分别为83%(95% CI 37-98)和64%(95% CI 42-81),对TFCC损伤的敏感性和特异性分别为78%(95% CI 57-91)和80%(95% CI 54-93)。曲线下面积为 0.91(95% CI 0.89-0.94),表明 CBCT 关节造影对 SLL 损伤的诊断准确性极高。CBCT 关节造影的估计平均有效剂量为 3.2 mSv (2.0-4.8)。结论:我们的研究证实,CBCT 关节造影术对腕关节韧带损伤具有极高的诊断准确性,其敏感性和特异性与传统关节造影术相当。虽然还需要更多采用更可靠方法的研究来支持其在临床实践中的应用,但我们的分析表明,它是一种可靠的选择,而且前景广阔。证据等级:三级(诊断)。
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引用次数: 0
Triphasic Bone Scintigraphy Is Not Useful in Diagnosis and May Delay Surgical Treatment of CRPS of the Hand. 三相骨闪烁扫描对诊断手部 CRPS 毫无用处,还可能延误手术治疗。
IF 0.5 Q4 SURGERY Pub Date : 2025-02-01 Epub Date: 2024-11-12 DOI: 10.1142/S2424835525500109
Francisco Del Piñal, Jin Xi Lim, Daniel C Williams, Jaime S Rúas, Alexis T Studer

Background: Triphasic bone scintigraphy (TPBS) is often used to diagnose complex regional pain syndrome (CRPS). The primary aim of this study is to determine if the diagnosis of CRPS in patients with a positive TPBS (TPBS +ve) is accurate. A secondary aim is to determine if there was delay in treatment of patients who underwent TPBS compared to those who did not have a TPBS. Methods: Of 225 consecutive patients presenting to the first author's practice with a diagnosis of CRPS, 65 had TPBS performed before referral with 62 having TPBS +ve. The remaining 160 were clinically diagnosed and a TPBS was not done (TPBS-ND). Patients were classified into five categories - wrong diagnosis, dystonic-psychogenic hand, causalgia, flare reaction and irritative carpal tunnel syndrome (ICTS). Patients with flare reaction and ICTS were considered as having true CRPS and the rest were considered as misdiagnosis. The patients' demographics, duration of symptoms, pre- and postoperative pain, functional score and patient satisfaction were compared. Results: Of the 62 TPBS +ve, there were 38 (61%) misdiagnosis. The proportion of misdiagnoses was fewer in the TPBS-ND group (45%; p = 0.036). Thirty-two of the 62 TPBS group (52%) and 92/160 (56%) of the TPBS-ND group had surgical treatment. At a mean follow-up of 19 months, pain dropped 6.5 ± 2.5 points in the TPBS +ve group. Disabilities of the arm, shoulder and hand (DASH) score fell by 56 ± 27. The mean single assessment numeric evaluation (SANE) score was 8.6 ± 2.3. These results did not differ substantially from those of the TPBS-ND group. Conclusions: A significant number of patients in this study who had TPBS +ve were misdiagnosed in this study. Outcomes after treatment of CRPS were consistently good despite the results of the TPBS. Patients with TPBS +ve had a significant delay to diagnosis. We conclude that TPBS is not useful in the management of CRPS. Level of Evidence: Level III (Therapeutic).

背景:三相骨闪烁扫描(TPBS)通常用于诊断复杂性区域疼痛综合征(CRPS)。本研究的主要目的是确定 TPBS 阳性(TPBS +ve)患者的 CRPS 诊断是否准确。次要目的是确定与未接受 TPBS 检查的患者相比,接受 TPBS 检查的患者是否会延误治疗。方法:在第一作者诊所就诊的 225 名诊断为 CRPS 的连续患者中,有 65 人在转诊前接受了 TPBS 检查,其中 62 人的 TPBS 为 +ve。其余 160 人经临床诊断后未进行 TPBS(TPBS-ND)。患者被分为五类--错误诊断、肌强直-心理性手部、因果痛、发作反应和刺激性腕管综合征(ICTS)。耀斑反应和刺激性腕管综合征患者被视为真正的 CRPS 患者,其余患者被视为误诊。比较了患者的人口统计学特征、症状持续时间、术前和术后疼痛、功能评分和患者满意度。结果:在 62 名 TPBS +ve 患者中,有 38 人(61%)被误诊。TPBS-ND 组的误诊比例较低(45%;P = 0.036)。62 名 TPBS 组患者中有 32 人(52%)和 92/160 名 TPBS-ND 组患者(56%)接受了手术治疗。在平均 19 个月的随访中,TPBS +ve 组的疼痛程度下降了 6.5 ± 2.5 分。手臂、肩部和手部残疾(DASH)评分下降了 56 ± 27 分。平均单次数字评估(SANE)得分为(8.6 ± 2.3)分。这些结果与 TPBS-ND 组的结果没有实质性差异。结论本研究中有大量 TPBS +ve 患者被误诊。尽管 TPBS 的结果不同,但 CRPS 治疗后的疗效始终良好。TPBS +ve 患者的诊断时间明显延迟。我们的结论是,TPBS 对 CRPS 的治疗并无益处。证据等级:三级(治疗)。
{"title":"Triphasic Bone Scintigraphy Is Not Useful in Diagnosis and May Delay Surgical Treatment of CRPS of the Hand.","authors":"Francisco Del Piñal, Jin Xi Lim, Daniel C Williams, Jaime S Rúas, Alexis T Studer","doi":"10.1142/S2424835525500109","DOIUrl":"10.1142/S2424835525500109","url":null,"abstract":"<p><p><b>Background:</b> Triphasic bone scintigraphy (TPBS) is often used to diagnose complex regional pain syndrome (CRPS). The primary aim of this study is to determine if the diagnosis of CRPS in patients with a positive TPBS (TPBS +ve) is accurate. A secondary aim is to determine if there was delay in treatment of patients who underwent TPBS compared to those who did not have a TPBS. <b>Methods:</b> Of 225 consecutive patients presenting to the first author's practice with a diagnosis of CRPS, 65 had TPBS performed before referral with 62 having TPBS +ve. The remaining 160 were clinically diagnosed and a TPBS was not done (TPBS-ND). Patients were classified into five categories - wrong diagnosis, dystonic-psychogenic hand, causalgia, flare reaction and irritative carpal tunnel syndrome (ICTS). Patients with flare reaction and ICTS were considered as having true CRPS and the rest were considered as misdiagnosis. The patients' demographics, duration of symptoms, pre- and postoperative pain, functional score and patient satisfaction were compared. <b>Results:</b> Of the 62 TPBS +ve, there were 38 (61%) misdiagnosis. The proportion of misdiagnoses was fewer in the TPBS-ND group (45%; <i>p</i> = 0.036). Thirty-two of the 62 TPBS group (52%) and 92/160 (56%) of the TPBS-ND group had surgical treatment. At a mean follow-up of 19 months, pain dropped 6.5 ± 2.5 points in the TPBS +ve group. Disabilities of the arm, shoulder and hand (DASH) score fell by 56 ± 27. The mean single assessment numeric evaluation (SANE) score was 8.6 ± 2.3. These results did not differ substantially from those of the TPBS-ND group. <b>Conclusions:</b> A significant number of patients in this study who had TPBS +ve were misdiagnosed in this study. Outcomes after treatment of CRPS were consistently good despite the results of the TPBS. Patients with TPBS +ve had a significant delay to diagnosis. We conclude that TPBS is not useful in the management of CRPS. <b>Level of Evidence:</b> Level III (Therapeutic).</p>","PeriodicalId":51689,"journal":{"name":"Journal of Hand Surgery-Asian-Pacific Volume","volume":" ","pages":"34-41"},"PeriodicalIF":0.5,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142632014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reliability of Hand-Held Dynamometer Measurement for Thumb Palmar Abduction Strength in Carpal Tunnel Syndrome. 手持式测力仪测量腕管综合征拇指掌外展强度的可靠性。
IF 0.5 Q4 SURGERY Pub Date : 2025-01-17 DOI: 10.1142/S2424835525500262
Kazuteru Doi, Noritada Yasui, Yuya Isomura, Masafumi Tagawa, Yasunori Hattori, Sotetsu Sakamoto

Background: In carpal tunnel syndrome (CTS), pain and sensory disturbance are the main symptoms, but thumb palmar abduction (TPA) paralysis cannot be ignored as a concurrent symptom. The reliable quantitative measurement of TPA power was not established. The purpose of this study was to report on the reliability of TPA strength measurements by the hand-held dynamometry (HHD) in large samples of CTS and its superiority over other tests, including grip, pinch powers, TPA angles and manual muscle testing, in terms of clinical progress indicators. Methods: We examined the relative and absolute reliabilities of the perioperative TPA strength measured by HHD (HHD-TPA) in 566 participants with CTS and the correlation coefficient between the HHD-TPA and other clinical tests. Results: The reliability of the HHD-TPA was intraclass correlation coefficients: 97% or higher. The Bland-Altman absolute reliability showed a random pattern of bias, and the minimal detectable changes (MDC) of the inter-rater and intra-rater reliabilities indicated 9.0 N and 7.0 N individually. The HHD-TPA showed statistically significant recoveries between perioperative stages; however, the mean difference larger than the MDC was recognised only between the preoperative and 12-month postoperative stages by intra-rater comparison. More individual patients showed recovery of HHD-TPA beyond the MDC when the same examiner continuously measured HHD-TPA than when multiple examiners continuously measured HHD-TPA. Grip strength and pinch strength measurements showed a strong correlation with HHD-TPA and did not show statistically significant improvement during the perioperative period. Conclusions: HHD-TPA is the most reliable method for quantifying muscle strength in the perioperative course of TPA force in CTS. HHD-TPA is a more reliable assessment of CTS motor recovery when measured consistently for each patient by the same hand therapist. Level of Evidence: Level IV (Diagnostic).

背景:在腕管综合征(CTS)中,疼痛和感觉障碍是主要症状,但拇指掌外展(TPA)麻痹是不可忽视的并发症状。TPA功率的可靠定量测量方法尚未建立。本研究的目的是报道在CTS大样本中,手持式测力仪(HHD)测量TPA强度的可靠性,以及它在临床进展指标方面优于其他测试,包括握力、捏力、TPA角度和手动肌肉测试。方法:对566例CTS患者进行HHD测量围手术期TPA强度(HHD-TPA)的相对可靠性和绝对可靠性,以及HHD-TPA与其他临床指标的相关系数。结果:HHD-TPA组内相关系数为97%以上。Bland-Altman绝对信度呈随机偏倚,评分间和评分内信度的最小可检测变化(MDC)分别为9.0 N和7.0 N。hdd - tpa围手术期患者康复率有统计学意义;然而,只有在术前和术后12个月的比较中才发现比MDC大的平均差异。当同一名检查人员连续测量hdd - tpa时,比多名检查人员连续测量hdd - tpa时,更多个体患者的hdd - tpa恢复超过MDC。握力和捏紧力测量与hdd - tpa有很强的相关性,围手术期无统计学意义的改善。结论:HHD-TPA是CTS围手术期肌力测量最可靠的方法。hdd - tpa是一种更可靠的CTS运动恢复评估方法,由同一手部治疗师对每个患者进行一致的测量。证据等级:四级(诊断性)。
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引用次数: 0
Paediatric Locked Middle Finger due to Synovial Osteochondromatosis: A Case Report. 滑膜骨软骨瘤病致小儿中指锁定1例报告。
IF 0.5 Q4 SURGERY Pub Date : 2025-01-17 DOI: 10.1142/S2424835525720038
Shichoh Sonezaki, Hikaru Ogawa, Yoshinao Oda, Tetsuo Kojima

Synovial osteochondromatosis is a relatively rare condition of the hand. We present a rare case of a locked finger in a paediatric patient with synovial osteochondromatosis, in which a tumourous lesion was continuous with the flexor tendon and trapped proximal to the A1 pulley. After resection of the tumour and synovium, no recurrence was observed over a 6-month follow-up period. Synovial osteochondromatosis in the hand or fingers can lead to swelling and limited range of motion; however, symptom progression is usually slow. Moreover, it is uncommon for an extra-articular tumour to cause a sudden onset of locking symptoms without prior warning signs. Comprehensive excision of the synovium is essential, and ongoing observation for recurrence is necessary during follow-up. Level of Evidence: Level V (Therapeutic).

滑膜骨软骨瘤病是一种相对罕见的手部疾病。我们报告一例罕见的滑膜骨软骨瘤病患儿手指被锁住的病例,其肿瘤病变连续出现在屈肌腱上,并被困在A1滑轮的近端。切除肿瘤和滑膜后,随访6个月未见复发。手部或手指滑膜骨软骨瘤病可导致肿胀和活动范围受限;然而,症状进展通常是缓慢的。此外,它是罕见的关节外肿瘤引起突然发作的锁定症状,没有事先的警告迹象。全面切除滑膜是必要的,在随访中需要持续观察复发情况。证据等级:V级(治疗性)。
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引用次数: 0
Angiogenesis and Axonal Elongation in Decellularised Nerve Grafts Depend on the Surrounding Vascular Environment. 脱细胞神经移植物的血管生成和轴突伸长依赖于周围血管环境。
IF 0.5 Q4 SURGERY Pub Date : 2025-01-10 DOI: 10.1142/S2424835525500183
Kaguna Tanimoto, Akira Kodama, Atsushi Kunisaki, Masaru Munemori, Naosuke Kamei, Nobuo Adachi

Background: Decellularised nerve transplantation has limited therapeutic efficacy for peripheral nerve injuries. In this study, we tested the hypothesis that nerve regeneration can be promoted by increasing blood circulation to the decellularised nerve through the surrounding blood-flow environment. Methods: We transplanted 20 mm decellularised nerves into sciatic nerve defects in Sprague-Dawley rats (female, 12 weeks old). In the intramuscular group, the decellularised nerve was implanted into the biceps femoris muscle and covered with the muscle to provide blood circulation. In the avascular group, the decellularised nerve was sutured to the sciatic nerve and the surrounding nerve bed was cauterised to create a non-bleeding field. In the intramuscular without repair group, the decellularised nerve was implanted in the biceps femoris muscle, but not sutured to the sciatic nerve. Axonal elongation and angiogenesis were evaluated immunohistochemically using anti-neurofilament, anti-S100 and anti-CD31 antibodies in sagittal and transverse sections of the nerve 3 weeks later. Results: In the intramuscular group, the number of neurofilaments per unit area and S100 were higher than those in the other groups (p < 0.05). CD31 staining was predominant in the intramuscular group. Axial images of the nerves confirmed the localisation of CD31-positive cells, and positive cells were found in the centre of the decellularised nerves in the intramuscular group. Conclusions: Decellularised nerve grafts wrapped with vascular-rich tissue promoted nerve regeneration by enhancing angiogenesis in transplanted nerve grafts and preventing ischemia in the centre of the nerve graft.

背景:去细胞神经移植治疗周围神经损伤的疗效有限。在这项研究中,我们验证了一个假设,即通过周围的血流环境增加去细胞化神经的血液循环可以促进神经再生。方法:将20 mm脱细胞神经移植到雌性大鼠(12周龄)坐骨神经缺损中。肌内注射组将脱细胞神经植入股二头肌内,覆盖于股二头肌外,提供血液循环。无血管组将脱细胞神经与坐骨神经缝合,烧灼周围的神经床,形成一个不出血的野。在肌内不修复组,脱细胞神经植入股二头肌,但不与坐骨神经缝合。3周后,采用矢状面和横切面抗神经丝、抗s100和抗cd31抗体免疫组织化学方法评估轴突伸长和血管生成。结果:肌内注射组单位面积神经丝数及S100均高于其他各组(p < 0.05)。肌内组以CD31染色为主。神经轴向图像证实了cd31阳性细胞的定位,肌内注射组的去细胞化神经中心发现了阳性细胞。结论:富血管组织包裹脱细胞神经移植物可促进移植物血管生成,防止移植物中枢缺血,从而促进神经再生。
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引用次数: 0
Accuracy of a Superficial Landmark of the Recurrent Branch of the Median Nerve and Anatomical Features of Transverse Muscle Fibres Observed During Carpal Tunnel Release. 腕管释放过程中正中神经复发支表面标记的准确性和横肌纤维解剖特征的观察。
IF 0.5 Q4 SURGERY Pub Date : 2025-01-10 DOI: 10.1142/S2424835525500250
Aya Kanazuka, Takane Suzuki, Yusuke Matsuura, Tomoyo Akasaka, Kazuki Kuniyoshi, Seiji Ohtori

Background: Surgeons use anatomical landmarks like the scaphoid tubercle, pisiform, trapezial tubercle and hook of hamate, along with Kaplan cardinal line (KCL) to avoid injury to the recurrent motor branch (RMB) of the median nerve during carpal tunnel release. The presence of transverse muscle fibres (TMF) overlying the transverse carpal ligament (TCL) may suggest proximity of the RMB, but their anatomical relationship is unclear. In this study, we evaluated the accuracy of anatomical landmarks to the RMB, TMF origin and insertion, and examined the relationship between TMF presence and RMB running patterns. Methods: We dissected 30 hands from 16 fresh-frozen cadavers. After marking the superficial landmarks, we made a skin incision to confirm the presence of TMF and examined their origins and insertions. We then opened the carpal tunnel, dissected the RMB and recorded each position on a coordinate system using a fluoroscopic imaging system. Results: TMF were observed in 18 hands (60%): 13 were continuous with the abductor pollicis brevis (APB), 2 were continuous with the superficial head of the flexor pollicis brevis (FPB) and 3 were continuous with both. The bifurcation point of the RMB was significantly located 4.5 mm ulnar and 7.5 mm proximal to the superficial landmark at the median. The RMB was classified according to Poisel classification: 24 (80%) were of the extraligamentous type, 4 (13%) of the transligamentous type, 1 (3%) of the preligamentous type and 1 (3%) of the subligamentous type. Amongst these, the transligamentous/preligamentous/subligamentous types are at high risk for RMB injury during TCL incision. No significant association existed between TMF presence and these high-risk RMB types.. Conclusions: The actual RMB may be located ulnar and proximal to the superficial landmark, indicating that surgeons should be cautious about RMB damage even in the absence of TMF.

背景:外科医生在进行腕管松解术时会使用肩胛结节、蝶形、斜方肌结节、锤骨钩等解剖标志物以及卡普兰心形线(KCL)来避免损伤正中神经的运动回流支(RMB)。覆盖在腕横韧带(TCL)上的横肌纤维(TMF)的存在可能表明正中神经靠近正中神经,但它们之间的解剖关系尚不清楚。在这项研究中,我们评估了解剖地标对人民币、TMF 起源和插入的准确性,并研究了 TMF 的存在与人民币运行模式之间的关系。研究方法我们从 16 具新鲜冷冻尸体上解剖了 30 只手。在标记浅表地标后,我们切开皮肤以确认颞下颌关节,并检查其起源和插入情况。然后,我们打开腕管,解剖人民币,并使用透视成像系统在坐标系上记录每个位置。结果:在 18 只手(60%)中观察到颞下颌关节:13 只手的颞下皱襞与拇外展肌 (APB) 连续,2 只手的颞下皱襞与拇屈肌浅头 (FPB) 连续,3 只手的颞下皱襞与拇外展肌和拇屈肌浅头都连续。RMB的分叉点明显位于尺侧4.5毫米和中线浅表标志近端7.5毫米处。根据 Poisel 分类法,RMB 分为韧带外型 24 例(80%)、经韧带型 4 例(13%)、韧带前型 1 例(3%)和韧带下型 1 例(3%)。其中,经韧带型/韧带前型/韧带下型是在切开 TCL 时造成人民币损伤的高危人群。TMF的存在与这些高风险RMB类型之间不存在明显关联。结论:实际的RMB可能位于尺侧和浅表标志的近端,这表明即使没有TMF,外科医生也应谨慎对待RMB损伤。
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Journal of Hand Surgery-Asian-Pacific Volume
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