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Effectiveness of Nerve Wrapping and Capping with a Nerve Conduit and Blocking Splint Therapy for a Painful Neuroma at the Metacarpophalangeal Joint. 神经导管包盖和阻断夹板治疗掌指关节疼痛性神经瘤的疗效。
IF 0.5 Q4 SURGERY Pub Date : 2025-01-05 DOI: 10.1142/S2424835525720026
Kosuke Shintani, Yutaka Kubota, Daisaku Matsuda

A 42-year-old man suffered an avulsion amputation of his right middle finger. He had undergone several surgeries since the age of 24, including amputation plasty and implantation of the injured nerve into fat and bone, but had difficulty returning to work due to persistent severe pain. He underwent nerve capping with an artificial nerve conduit at a university hospital, and his symptoms improved slightly, but immediately flared up again. Therefore, he was referred to our hospital and was treated with a blocking splint in addition to resection of the traumatic neuroma, covering with an artificial nerve conduit and wrapping with an adiposal flap. The lumen of the conduit was observed without collapse until it was resorbed, and he returned to work without pain 10 months after surgery. The blocking splint to an angle that preserves the lumen of the conduit was useful for artificial nerve surgery near the joint. Level of Evidence: Level V (Therapeutic).

一名42岁男子右手中指撕脱性截肢。从24岁开始,他接受了几次手术,包括截肢术和将受伤的神经植入脂肪和骨骼,但由于持续的剧烈疼痛,他很难重返工作岗位。他在一所大学医院接受了人工神经导管神经盖术,他的症状略有好转,但立即又发作了。因此,他被转诊到我们医院,除了切除外伤性神经瘤,用人工神经导管覆盖和脂肪瓣包裹外,还接受了封堵夹板治疗。观察到导管管腔未塌陷直至其被吸收,术后10个月患者无疼痛恢复工作。在关节附近的人工神经手术中,夹板的夹板夹持角度保留导管管腔是有用的。证据等级:V级(治疗性)。
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引用次数: 0
Nerve Capping Using Renerve® Synthetic Collagen Conduits for Hand Amputation Neuroma Pain. 使用Renerve®合成胶原蛋白导管治疗手部截肢神经瘤疼痛。
IF 0.5 Q4 SURGERY Pub Date : 2025-01-05 DOI: 10.1142/S2424835525500195
Shinsuke Takeda, Shigeru Kurimoto, Ryutaro Shibata, So Mitsuya, Hideki Okamoto, Hideki Murakami

Background: Amputated neuromas, a common consequence of peripheral nerve injury, can cause significant pain and may impair daily life. Herein, we conducted a retrospective study on patients who underwent a nerve-capping technique using the bioabsorbable nerve conduit Renerve®, with a minimum follow-up period of 6 months. Methods: We conducted a retrospective study to assess patients with amputation neuromas of the finger or palm who underwent surgical treatment using the capping technique with the Renerve® conduit between October 2018 and September 2022. The data on demographics, operative details, pre- and postoperative evaluations (visual analogue scale [VAS] pain scores and Tinel sign) and complications were analysed. Results: Seven patients (seven nerves) with a median age of 51 years (three men and four women) were assessed. The median follow-up duration was 15 months. Renerve® conduits of varying sizes (1.0-2.3 mm) and lengths (15-25 mm) were used. The median duration until surgery was 195 days. After the procedure, VAS pain scores significantly decreased from a baseline of 53.1 mm to 5.7 mm at the 6-month follow-up. Tinel sign persisted in four patients, and no postoperative complications occurred. Conclusions: Our study demonstrates the clinical usefulness of the Renerve® conduit as a nerve-capping technique for amputation neuroma. Considering the limited availability of real-world data on Renerve® conduits for nerve capping, our findings provide valuable insights for clinical practitioners. Level of Evidence: Level IV (Therapeutic).

背景:神经瘤切除是周围神经损伤的常见后果,可引起明显的疼痛并可能影响日常生活。在此,我们对使用生物可吸收神经导管Renerve®进行神经盖术的患者进行了回顾性研究,随访时间至少为6个月。方法:我们进行了一项回顾性研究,评估了2018年10月至2022年9月期间接受Renerve®导管盖顶技术手术治疗的手指或手掌截肢神经瘤患者。分析统计学数据、手术细节、术前和术后评估(视觉模拟评分[VAS]疼痛评分和Tinel体征)和并发症。结果:7例患者(7根神经),中位年龄51岁(男3名,女4名)。中位随访时间为15个月。使用不同尺寸(1.0-2.3 mm)和长度(15-25 mm)的reerve®导管。手术前的中位持续时间为195天。术后6个月随访时,VAS疼痛评分从基线53.1 mm显著下降至5.7 mm。4例患者仍有时间征,无术后并发症发生。结论:我们的研究证明了Renerve®导管作为一种神经覆盖技术用于截肢神经瘤的临床有效性。考虑到Renerve®导管用于神经盖的真实数据的有限可用性,我们的研究结果为临床从业者提供了有价值的见解。证据等级:IV级(治疗性)。
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引用次数: 0
Generative Artificial Intelligence Responses to Common Patient-Centric Hand and Wrist Surgery Questions: A Quality and Usability Analysis. 生成人工智能响应常见的以患者为中心的手和手腕手术问题:质量和可用性分析。
IF 0.5 Q4 SURGERY Pub Date : 2025-01-05 DOI: 10.1142/S2424835525500171
Benjamin Pautler, Charles Marchese, Makayla Swancutt, Bryan G Beutel

Background: Due to the rapid evolution of generative artificial intelligence (AI) and its implications on patient education, there is a pressing need to evaluate AI responses to patients' medical questions. This study assessed the quality and usability of responses received from two prominent AI platforms to common patient-centric hand and wrist surgery questions. Methods: Twelve commonly encountered hand and wrist surgery patient questions were inputted twice into both Gemini and ChatGPT, generating 48 responses. Each response underwent a content analysis, followed by assessment for quality and usability with three scoring tools: DISCERN, Suitability Assessment of Materials (SAM) and the AI Response Metric (AIRM). Statistical analyses compared the features and scores of the outputs when stratified by platform, question type and response order. Results: Responses earned mean overall scores of 55.7 ('good'), 57.2% ('adequate') and 4.4 for DISCERN, SAM and AIRM, respectively. No responses provided citations. Wrist question responses had significantly higher DISCERN (p < 0.01) and AIRM (p = 0.02) scores compared to hand responses. Second responses had significantly higher AIRM (p < 0.01), but similar DISCERN (p = 0.76) and SAM (p = 0.11), scores compared to the first responses. Gemini's DISCERN (p = 0.04) and SAM (p < 0.01) scores were significantly higher than ChatGPT's corresponding metrics. Conclusions: Although responses are generally 'good' and 'adequate', there is variable quality with respect to platform used, type of question and response order. Given the diversity of publicly available AI platforms, it is important to understand the quality and usability of information patients may encounter during their search for answers to common hand and wrist surgery questions. Level of Evidence: Level IV (Therapeutic).

背景:由于生成式人工智能(AI)的快速发展及其对患者教育的影响,迫切需要评估AI对患者医疗问题的反应。本研究评估了从两个著名的人工智能平台收到的以患者为中心的常见手部和手腕手术问题的回答的质量和可用性。方法:在Gemini和ChatGPT中两次输入12个手部和手腕手术患者常见的问题,得到48个回复。每个回复都进行了内容分析,然后使用三种评分工具进行质量和可用性评估:DISCERN,材料适用性评估(SAM)和人工智能响应度量(AIRM)。统计分析比较了按平台、问题类型和回答顺序分层的输出的特征和分数。结果:回答的平均总分分别为55.7分(“好”),57.2%(“足够”)和4.4分,分别为DISCERN, SAM和AIRM。没有答复提供引文。腕部问题回答的DISCERN (p < 0.01)和AIRM (p = 0.02)得分显著高于手部回答。与第一反应相比,第二反应的AIRM得分显著高于第一反应(p < 0.01),而DISCERN (p = 0.76)和SAM (p = 0.11)得分相似。Gemini的DISCERN (p = 0.04)和SAM (p < 0.01)得分显著高于ChatGPT的相应指标。结论:虽然回答通常是“好”和“适当”的,但就使用的平台、问题类型和回答顺序而言,质量是可变的。鉴于公开可用的人工智能平台的多样性,了解患者在寻找常见手部和手腕手术问题的答案时可能遇到的信息的质量和可用性非常重要。证据等级:IV级(治疗性)。
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引用次数: 0
The Higher Positive Amyloid Deposition in Electrophysiologically Proven Idiopathic Carpal Tunnel Syndrome Patients. 经电生理学证实的特发性腕管综合征患者较高的淀粉样蛋白阳性沉积。
IF 0.5 Q4 SURGERY Pub Date : 2025-01-05 DOI: 10.1142/S2424835525500274
Haruka Maehara, Nobuaki Tadokoro, Hiroaki Ueba, Masahiko Ikeuchi

Background: Carpal tunnel syndrome (CTS) due to amyloid deposition was reported to precede fatal cardiac amyloidosis by several years. Although nerve conduction study (NCS) supports CTS diagnosis, the incidence of positive amyloid deposition in electrophysiologically proven CTS is unclear. Methods: We retrospectively analysed the demographic data including age, gender, bilateral hand involvement, amyloid deposition and NCS results, of 111 consecutive CTS patients with postoperative symptom improvement (mean 71.1 years old, male/female ratio: 44/67) who simultaneously underwent carpal tunnel release (CTR) and biopsy for amyloid deposition. Results: Electrophysiologically proven CTS patients were 102 (91.9%) out of 111 patients. Amyloid deposition was detected in 62 hands (55.9%), of which 51 were transthyretin amyloid. The NCS severity was associated with a higher prevalence of positive amyloid deposition (p < 0.01). The NCS severity also showed an increased trend between reported risk factors for positive amyloid deposition such as older age, male gender and bilateral hand symptoms (p < 0.01). Conclusions: The prevalence of positive amyloid deposition was higher than previous reports in this study. Abnormal NCS findings in CTS, such as an increased distal motor latency (DML) of abductor pollicis brevis compound muscle action potentials (APB-CMAP) or absent APB-CMAP, may help to increase the pre-test probability of amyloid deposition in tenosynovial biopsy. Level of Evidence: Level IV (Diagnostic Study).

背景:据报道,由于淀粉样蛋白沉积引起的腕管综合征(CTS)比致命性的心脏淀粉样变性早几年发生。尽管神经传导研究(NCS)支持CTS的诊断,但在电生理学证实的CTS中,淀粉样蛋白阳性沉积的发生率尚不清楚。方法:回顾性分析111例术后症状改善的连续CTS患者(平均71.1岁,男女比例:44/67)的人口统计学资料,包括年龄、性别、双侧手受损伤、淀粉样蛋白沉积和NCS结果,这些患者同时接受了腕管释放(CTR)和淀粉样蛋白沉积活检。结果:电生理学证实的CTS患者102例(91.9%)。62例(55.9%)手部检出淀粉样蛋白沉积,其中51例为转甲状腺素淀粉样蛋白。NCS严重程度与较高的淀粉样蛋白阳性沉积发生率相关(p < 0.01)。NCS严重程度在报告的淀粉样蛋白沉积阳性危险因素(如年龄较大、男性和双侧手症状)之间也显示出增加的趋势(p < 0.01)。结论:本研究中淀粉样蛋白阳性沉积的发生率高于以往的报道。CTS的异常NCS表现,如外展拇短肌复合肌动作电位(APB-CMAP)远端运动潜伏期(DML)增加或APB-CMAP缺失,可能有助于增加腱鞘活检中淀粉样蛋白沉积的测试前概率。证据等级:四级(诊断性研究)。
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引用次数: 0
Platelet-Rich Plasma versus Corticosteroid Injection for the Treatment of de Quervain Tenosynovitis: A Randomised Control Open Label Equivalence Trial. 富血小板血浆与皮质类固醇注射治疗去Quervain腱鞘炎:一项随机对照开放标签等效试验。
IF 0.5 Q4 SURGERY Pub Date : 2025-01-05 DOI: 10.1142/S2424835525500249
Prasenjit Chowley, Harajit Biswas, Keshab Mondal, Shrabasti Hazra, Sandipan Hazra, Pallab DAS

Background: De Quervain (DQ) tenosynovitis is a frequent source of wrist pain amongst middle-aged adults. Steroid injections are recommended after conservative methods fail, despite unclear mechanisms. The effectiveness of platelet-rich plasma (PRP) for DQ is not well-studied. To address this gap, we conducted a randomised controlled trial comparing the efficacy of PRP and corticosteroid (CS) injections for treating DQ. Methods: This prospective, randomised and open-label trial was conducted at a tertiary care hospital in India. Adult patients aged 18-60 were randomly assigned to receive either ultrasound-guided triamcinolone acetonide injections or autologous PRP in the first extensor compartment. Outcomes were measured at baseline and at 1, 4 and 12 weeks using the VAS and quick disabilities of arm, shoulder and hand (QuickDASH) questionnaires. Results: Eighty-six age- and sex-matched patients, with an average disease duration of 14 weeks in both groups, were enrolled. Both the CS and PRP groups demonstrated a significant reduction in pain scores and improvement in functions at 1, 4 and 12 weeks. However, between the groups, the degree of improvement in pain was more in CS group at 1 week and similar improvements between the groups at 4 and 12 weeks. Regarding hand function, the CS group exhibited notable at 1 and 4 weeks based on the QuickDASH scale. Yet, by the 12th week, hand function improvements were comparable between both groups. Conclusions: This study suggests that PRP is equivalent to CS in reducing pain in DQ tenosynovitis. Hand function improved more significantly in the CS group at 1 and 4 weeks post-injection. Both PRP and CS are safe and equally effective treatments for DQ. Level of Evidence: Level I (Therapeutic).

背景:德Quervain (DQ)型腱鞘炎是中年人手腕疼痛的常见原因。在保守方法失败后,建议注射类固醇,尽管机制尚不清楚。富血小板血浆(PRP)治疗DQ的有效性尚未得到充分研究。为了解决这一差距,我们进行了一项随机对照试验,比较PRP和皮质类固醇(CS)注射治疗DQ的疗效。方法:这项前瞻性、随机和开放标签试验在印度的一家三级保健医院进行。18-60岁的成年患者被随机分配接受超声引导的曲安奈德注射或在第一伸肌室接受自体PRP。使用VAS和手臂、肩膀和手的快速残疾(QuickDASH)问卷在基线和1、4和12周测量结果。结果:86例年龄和性别匹配的患者入组,两组平均病程为14周。CS组和PRP组在1周、4周和12周时均表现出疼痛评分显著降低和功能改善。然而,在两组之间,CS组在1周时疼痛的改善程度更大,在4周和12周时两组之间的改善程度相似。在手部功能方面,根据QuickDASH量表,CS组在第1周和第4周表现显著。然而,到第12周时,两组患者的手部功能改善具有可比性。结论:本研究提示PRP在减轻DQ型腱鞘炎疼痛方面与CS相当。注射后1周和4周,CS组手部功能改善更为显著。PRP和CS都是安全且同样有效的DQ治疗方法。证据等级:I级(治疗性)。
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引用次数: 0
Advanced Surgical Training Models for Wrist Surgery. 手腕外科高级外科训练模式。
IF 0.5 Q4 SURGERY Pub Date : 2025-01-05 DOI: 10.1142/S242483552597001X
Simon B M Maclean, Greg I Bain

Globally, surgical exposure for the trainee has become challenging due to changes in shift patterns, increasing medicolegal issues and the recognition of burnout. Simulation models are a crucial adjunct for the development of arthroscopic skills and open procedures. Advanced anatomically precise 3D-printed wrist models are used in our workshops. The models have pathological lesions within, allowing a range of arthroscopic and open procedures to be performed. Pathology can be ordered on-demand. Arthroscopic and open procedures can be performed, including fracture fixation and arthroplasty. For effective teaching, we use a lab-based environment with basic arthroscopic and open equipment and implants available. We use a specific structure in which to teach trainees, including pre-course material, videos, demonstrations, practice and feedback. Advanced surgical training models for wrist surgery allow for safe, repetitive surgical training to allow the trainee to accelerate their learning curve. Level of Evidence: Level V (Therapeutic).

在全球范围内,由于轮班模式的变化,越来越多的医学法律问题和对倦怠的认识,培训生的手术暴露变得具有挑战性。模拟模型是关节镜技术和开放手术发展的重要辅助手段。先进的解剖精确的3d打印手腕模型在我们的车间使用。模型内部有病理病变,允许进行一系列关节镜和开放手术。病理可以按需排序。可进行关节镜和开放手术,包括骨折固定和关节成形术。为了有效的教学,我们使用了一个基于实验室的环境,有基本的关节镜和开放设备和植入物。我们使用特定的结构来教授学员,包括课前材料、视频、演示、练习和反馈。先进的手腕手术手术训练模型允许安全,重复的手术训练,让受训者加快他们的学习曲线。证据等级:V级(治疗性)。
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引用次数: 0
The Initial Characteristics of Paediatric Supracondylar Humerus Fractures Led to Cubitus Varus Deformity and Delayed Displacement. 小儿肱骨髁上骨折导致肘内翻畸形和迟发性移位的初始特征。
IF 0.5 Q4 SURGERY Pub Date : 2025-01-05 DOI: 10.1142/S2424835525500237
Takehiko Takagi, Noriyuki Aibara, Sakura Yamaguchi, Atsuhito Seki, Shinichiro Takayama

Background: Supracondylar humerus fractures are the most common type of elbow fracture in children, with a variety of complications such as cubitus varus deformity. The most important goal of the initial treatment is to avoid complicated deformities. In the present study, we investigated cubitus varus deformity and discussed the ideal initial treatment for supracondylar humerus fractures. Methods: There were 58 conservative cases (26 girls and 32 boys) and 115 operative cases (40 girls and 75 boys) with supracondylar humerus fractures. We evaluated the correlation between the following factors on injury in the conservative cases: Gartland classification, presence of comminuted medial fractures, medial shift length, anterior spike length, age, sex, affected side (as explanatory variables) and the factors of cubitus varus deformity as response variables by using the linear regression model for multivariable analysis. Moreover, we evaluated the changes in displacement after the operation in the operative cases, adding the presence of medial pins and the number of pins as explanatory variables. Results: Injury severity (Gartland classification) was a significant factor for cubitus varus deformity. The presence of comminuted bone fragments on the medial side, anterior spike length, age, sex and affected side were not significant factors of cubitus varus deformity. However, medial displacement on injury was a significant factor of both cubitus varus deformity. In the operative case study, medial displacement was a significant factor in cubitus varus deformity. The presence of comminuted bone fragments on the medial side, number of pins and age were also significant factors for cubitus varus deformities. Conclusions: The present study concluded that it is important to perform accurate reduction and fixation, with special attention to medial shift and medial comminuted fragments to avoid cubitus varus deformity. Level of Evidence: Level IV (Therapeutic).

背景:肱骨髁上骨折是儿童肘部骨折中最常见的类型,并伴有肘内翻畸形等多种并发症。初期治疗最重要的目标是避免复杂的畸形。在本研究中,我们研究了肘内翻畸形,并讨论了肱骨髁上骨折的理想初始治疗方法。方法:保守治疗肱骨髁上骨折58例(女26例,男32例),手术治疗115例(女40例,男75例)。我们采用线性回归模型进行多变量分析,评估保守病例中以下因素与损伤的相关性:Gartland分类、内侧粉碎性骨折的存在、内侧移位长度、前钉长度、年龄、性别、受累侧(作为解释变量)和肘内翻畸形因素作为响应变量。此外,我们评估了手术病例术后移位的变化,并将内侧钉的存在和钉的数量作为解释变量。结果:损伤严重程度(Gartland分类)是肘内翻畸形的重要因素。内侧是否有粉碎的骨碎片、前钉长度、年龄、性别和患侧对肘内翻畸形无显著影响。然而,损伤后内侧移位是双肘内翻畸形的重要因素。在手术病例研究中,内侧移位是肘内翻畸形的重要因素。内侧是否存在粉碎的骨碎片、钉钉数量和年龄也是肘内翻畸形的重要因素。结论:本研究得出结论,准确复位和固定是重要的,特别注意内侧移位和内侧粉碎碎片,以避免肘内翻畸形。证据等级:IV级(治疗性)。
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引用次数: 0
Synovial Chondromatosis of the Hand and Wrist: A 35-Year Retrospective Case Review. 手和手腕滑膜软骨瘤病:35年回顾性病例回顾。
IF 0.5 Q4 SURGERY Pub Date : 2025-01-05 DOI: 10.1142/S2424835525500213
Holly Morris, Victoria Lo, Becky Sheehy, Karen L Smith

Background: Synovial chondromatosis is a condition that rarely occurs in the hand and wrist. Recurrence and malignant transformation are two potential complications of the disease. We set out to retrospectively review 35 years of practice within our sarcoma and tertiary hand unit and identify recurrence or malignant transformation. Methods: This is a retrospective analysis of patients with synovial chondromatosis seen at our sarcoma and tertiary hand unit for the past 35 years. Incidence of recurrence or malignant transformation was noted. Where possible, patients were clinically and radiologically reviewed with range of motion, grip strength and patient evaluation measures obtained. Results: Of 12 patients presenting to the practice, seven patients were followed up and, of these, two demonstrated recurrences. The recurrence was diagnosed based on patient-reported symptoms, clinical examination and the requisition of further imaging. Of the five who could not be followed up, two demonstrated recurrence and one had malignant transformation with a low-grade chondrosarcoma on histology. Conclusions: While a rare disease, we demonstrated recurrence within our small case series. Fusion to obliterate the joint is an option in the management of recurrence. For the diagnostically challenging, genetic testing may be beneficial, though genetic rearrangements are not seen in all cases. All patients should be counselled on symptoms to watch for as a small proportion may experience recurrence and a small percentage may undergo malignant transformation. Level of Evidence: Level IV (Therapeutic).

背景:滑膜软骨瘤病是一种很少发生在手腕部的疾病。复发和恶性转化是本病的两种潜在并发症。我们开始回顾性回顾35年的肉瘤和第三手单位的实践,并确定复发或恶性转化。方法:回顾性分析过去35年来在我们的肉瘤和第三手单位见过的滑膜软骨瘤病患者。观察复发或恶性转化的发生率。在可能的情况下,对患者进行临床和放射学检查,获得运动范围,握力和患者评估措施。结果:在12例患者中,7例患者接受了随访,其中2例复发。根据患者报告的症状、临床检查和进一步影像学检查的要求诊断复发。未能随访的5例患者中,2例复发,1例组织学表现为恶性转化伴低级别软骨肉瘤。结论:虽然这是一种罕见的疾病,但我们在我们的小病例系列中发现了复发。融合术消除关节是治疗复发的一种选择。对于具有挑战性的诊断,基因检测可能是有益的,尽管基因重排并不见得在所有情况下。所有患者应告知症状,以观察,因为一小部分患者可能会复发,一小部分患者可能会发生恶性转化。证据等级:IV级(治疗性)。
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引用次数: 0
The Microbiology, Management and Outcomes of Native Joint Septic Arthritis of the Hand in Adults of Southeast Queensland. 昆士兰东南部成人原发性关节感染性关节炎的微生物学、管理和预后。
IF 0.5 Q4 SURGERY Pub Date : 2025-01-05 DOI: 10.1142/S2424835525500201
Lee Forman, Ariadne Forman, Kylie Alcorn

Background: Native joint septic arthritis (NJSA) of the hand is poorly studied. Management guidelines are extrapolated from large joint infections despite differences in epidemiology, anatomy and aetiology. Limited evidence suggests shorter courses of antibiotics can achieve outcomes comparable to longer courses. The aim of our study is to characterise the presentation, management and outcomes of NJSA of the hand in an adult cohort from Southeast Queensland (SEQ) and determine if the route or duration of antibiotics affected the outcome. Our cohort was compared to those in the literature to determine if already published data could be applicable to our population. Methods: A coding based retrospective cohort of adult patients between 2016 and 2022 were assessed. The cohort was divided into short/long course antibiotics and primarily intravenous/oral route for outcome comparison. Results: Seventy-four patients were included with a joint culture positive rate of 75%. The most common aetiology of infection was direct trauma and the most common pathogen was Staphylococcus aureus. Resolution was achieved in 86% of patients after 1-year follow-up, with a median antibiotic duration of 14 days, and 48% had non-infectious sequelae. Failure to achieve resolution was associated with females and taking immunosuppressants. No significant difference was detected when analysed for primary route or duration of antibiotics. Conclusions: There was no difference in the rate of resolution attributable to the route or duration of antibiotics. We demonstrated comparability between our cohorts' demographics, management and outcomes with those in the literature. Based on the findings in our study, noting the retrospective nature and small cohort, the authors conclude for uncomplicated NJSA of the hand, a total antibiotic duration of 14 days in addition to early surgical intervention is likely to be successful in most patients. Level of Evidence: Level III (Therapeutic).

背景:手部原生关节感染性关节炎(NJSA)的研究很少。尽管在流行病学、解剖学和病因上存在差异,但管理指南是从大关节感染中推断出来的。有限的证据表明,较短疗程的抗生素可以达到与较长疗程相当的效果。我们研究的目的是描述来自昆士兰东南部(SEQ)的成人队列中手部NJSA的表现、管理和结果,并确定抗生素的使用途径或持续时间是否影响结果。将我们的队列与文献中的队列进行比较,以确定已发表的数据是否适用于我们的人群。方法:对2016年至2022年的成年患者进行基于编码的回顾性队列研究。该队列分为短/长疗程抗生素和主要静脉/口服途径进行结果比较。结果:74例患者入组,关节培养阳性率75%。感染最常见的病因是直接创伤,最常见的病原体是金黄色葡萄球菌。经过1年的随访,86%的患者得到了缓解,抗生素的中位持续时间为14天,48%的患者有非感染性后遗症。治疗失败与女性和服用免疫抑制剂有关。当分析抗生素的主要途径或持续时间时,未发现显着差异。结论:抗生素的使用途径和使用时间对患者的解决率没有影响。我们证明了我们的队列的人口统计、管理和结果与文献中的结果之间的可比性。根据我们的研究结果,注意到回顾性和小队列,作者得出结论,对于手部非复杂性NJSA,除了早期手术干预外,总抗生素持续时间为14天可能对大多数患者成功。证据等级:III级(治疗性)。
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引用次数: 0
Outcome Measures after Peripheral Nerve Injury: Past, Present and Future. 周围神经损伤后的结局测量:过去、现在和未来。
IF 0.5 Q4 SURGERY Pub Date : 2024-12-27 DOI: 10.1142/S2424835525300014
Zachary D Randall, Brendan Navarro, Christopher J Dy

Peripheral nerve injuries (PNI) present substantial challenges due to variability in injury severity and limited regenerative capabilities. Historically, PNI research has focussed on measures such as subjective surgeon outcome grading, two-point discrimination (2PD) and the Medical Research Council (MRC) grading system. While these methods have use, there are also limitations related to subjectivity and sensitivity. Electrophysiological studies, including electromyography (EMG) and nerve conduction studies (NCS), provide detailed insights but are invasive and resource intensive. Currently, the landscape of outcome measurements in PNI research is diverse, incorporating a mix of surgeon-scored, patient-reported and objective measures. Advancements in wearable devices and motion-tracking technologies offer the potential for continuous, real-time monitoring of patient recovery. These innovations can provide a more comprehensive and objective view of functional recovery, moving beyond the limitations of periodic clinical assessments. The primary limitation in current PNI research is the lack of standardisation in outcome measures and the arbitrary timing of assessments. This variability complicates data interpretation and comparative effectiveness research. Standardising the selection and timing of outcome measures is crucial for enhancing the reliability of research findings and facilitating collaborative studies. Level of Evidence: Level V (Diagnostic).

周围神经损伤(PNI)由于损伤严重程度的可变性和有限的再生能力而面临着巨大的挑战。从历史上看,PNI研究主要集中在主观外科手术结果评分、两点区分(2PD)和医学研究委员会(MRC)评分系统等措施上。虽然这些方法有一定的用途,但也存在与主观性和敏感性有关的局限性。电生理研究,包括肌电图(EMG)和神经传导研究(NCS),提供了详细的见解,但具有侵入性和资源密集性。目前,PNI研究的结果测量方法是多种多样的,包括外科医生评分、患者报告和客观测量的混合。可穿戴设备和运动跟踪技术的进步为持续实时监测患者康复提供了可能。这些创新可以提供更全面和客观的功能恢复视图,超越了定期临床评估的局限性。目前PNI研究的主要限制是结果测量缺乏标准化和评估的任意时间。这种可变性使数据解释和比较有效性研究复杂化。结果测量的选择和时间的标准化对于提高研究结果的可靠性和促进合作研究至关重要。证据等级:V级(诊断性)。
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引用次数: 0
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Journal of Hand Surgery-Asian-Pacific Volume
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