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Nefritis lúpica Experiencia con dosis reducidas de glucocorticoides en una unidad de enfermedades autoinmunes sistémicas 狼疮肾炎经历减少剂量的糖皮质激素在一个单位的系统性自身免疫性疾病
IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2021-12-09 DOI: 10.29193/rmu.37.4.6
Adriana Carlomagno, G. Silveira, Ã. Danza, Ana Carina Pizzarossa, Martín Yandián, Federico Yandián, M. Rebella
Introduction: current recommendations to treat lupus nephritis (LN) point to low-dose glucocorticoids to control the disease and avoid cumulativedamage. Objective: to learn about and compare the response of patients with proliferative LN who are treated following two prednisone therapy guidelines: reduced initial doses <30 mg/d and standard initial doses >30 mg/d during the induction stage. Method: clinical, analytical and therapeutic guidelines of patients with proliferative LN were compared and classified into two groups according to the standard or low-dose initial prednisone dose. Results: 21 patients with proliferative LN were studied (n=12 low-dose initial prednisonevs. n=9 standard initial prednisone). No significant differences were found between clinical and analytical variables, although a significantly different statistic difference was observed in the number of methylprednisone pulses (5 ± 2.95 initial prednisone <30 mg/d vs 2.33 ± 2.91 initial prednisone >30 mg/d, p = 0.041) and in the prednisone dose accumulated in 6 months (12.8 mg ± 4.9 initial prednisone <30 mg/d vs 30.0 ± 13.1 mg initial prednisone >30 mg/d, p =0.008). Rev Méd Urug 2021; 37(4): e37407
目前治疗狼疮性肾炎(LN)的建议是使用低剂量的糖皮质激素来控制疾病并避免累积损害。目的:了解并比较两种泼尼松治疗指南治疗增生性LN患者的反应:在诱导阶段减少初始剂量30mg /d。方法:比较增殖性LN患者的临床、分析和治疗指南,按标准或低剂量泼尼松初始剂量分为两组。结果:研究了21例增生性LN患者(n=12例低剂量初始泼尼松)。N =9例标准初始强的松)。甲基强的松脉冲次数(5±2.95次初始强的松30 mg/d, p = 0.041)和6个月累积强的松剂量(12.8 mg±4.9次初始强的松30 mg/d, p =0.008)有统计学差异,但临床变量与分析变量间无统计学差异。Rev m2013.21;(4): 37 e37407
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引用次数: 0
Coagulopatía asociada al trauma en la Unidad de Cuidados Intensivos 在重症监护病房与创伤相关的凝血病
IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2021-12-09 DOI: 10.29193/rmu.37.4.5
P. Grille, Andrea Herrerín, Federico Verga
Resumen Introducción: la enfermedad traumática es un problema de salud mundial. La coagulopatía asociada al trauma (CAT) cons tituye una complicación grave, multifactorial y de diagnóstico controversial. Objetivos: valorar la incidencia de CAT, los factores asociados a su desarrollo y su asociación con el pronóstico, en una serie de pacientes traumatizados ingresados a la Unidad de Cuidados Intensivos de nuestro hospital. Pacientes y métodos: estudio prospectivo de todos los pacientes ingresados con diagnóstico de trauma grave a la UCI. Se definió CAT en base a los parámetros clásicos de laboratorio, por la presencia de al menos uno de: INR mayor a 1,3, plaque-topenia menor a 100.000/mm 3 , y/o aPTT mayor a 38 segundos. Las variables continuas se expresaron como la media ± desvío estándar. Se realizó análisis de chi cuadrado, test exacto de Fisher y regresión logística binaria para estudiar la asociación entre las variables. Se consideró significativo un valor p < 0,05. Resultados: se analizaron 103 pacientes, con media de edad de 33 años y predominio de sexo masculino. Se encontró CAT en 42 pacientes (40,8%), presentándose al ingreso hospitalario en la mayoría de los casos. Los factores de riesgo asociados a CAT fueron: gravedad al ingreso, shock, hipoperfusión, acidosis, transfusión masiva, sangrado significativo
本研究的目的是评估创伤后应激障碍患者的心理健康状况,并评估创伤后应激障碍患者的心理健康状况。创伤相关凝血病(CAT)是一种严重的、多因素的并发症,诊断有争议。目的:评估在本医院重症监护病房收治的一系列创伤患者中CAT的发生率、与其发展相关的因素及其与预后的关系。患者和方法:对所有在重症监护室被诊断为严重创伤的患者进行前瞻性研究。CAT的定义是基于经典的实验室参数,至少存在一种:INR大于1.3,板减少小于100,000 / mm3,和/或aPTT大于38秒。实变量表示为平均值±标准偏差。采用卡方分析、Fisher精确检验和二logistic回归分析变量之间的相关性。被认为显著值p < 0.05。摘要目的:探讨慢性阻塞性肺病(copd)和慢性阻塞性肺病(copd)之间的关系。我们在42例(40.8%)患者中发现了CAT,其中大多数是住院患者。与CAT相关的危险因素为:入院严重程度、休克、低灌注、酸中毒、大量输血、显著出血
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引用次数: 0
Características de las consultas de los recién nacidos en un servicio de emergencia pediátrica 儿科急诊服务中新生儿会诊的特点
IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2021-12-09 DOI: 10.29193/rmu.37.4.7
Mariana Más, A. Casuriaga, G. Giachetto, Carina Giacoia, Lucía Centena, M. López, Yelenna Ramírez
Introduction: the are by signifi-cant Objective: to describe the characteristics of newborn presentations to the pedriatric emergency department of a comprehensive health care provider between January 1 and December 31, 2018. Method: descriptive study by analysing medical re-cords and telephone interviews to mothers. Newborn, maternal and consultation variables were analysed. Results: 237 presentations were recorded, 209 of which corresponded to newborns, male neonates 53%, average age was 16 days. Diagnostics upon discharge were three categories:1) consultations childcare physiological processes Hospitalizationrate hospitalized:
前言:目的:描述2018年1月1日至12月31日期间某综合医疗机构儿科急诊科新生儿就诊的特点。方法:通过病历分析和母亲电话访谈进行描述性研究。分析新生儿、产妇和咨询变量。结果:237例,其中新生儿209例,男新生儿53%,平均年龄16天。出院诊断分为三类:1)会诊托儿生理过程住院率;
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引用次数: 0
Caracterización de pacientes con microcarcinoma papilar de tiroides en el Hospital de Clínicas (UDELAR) en los últimos 10 años 临床医院(UDELAR)近10年甲状腺乳头状微癌患者的特征
IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2021-12-09 DOI: 10.29193/rmu.37.4.4
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引用次数: 0
Homicidios intencionales en la salud. Un tema huérfano de la seguridad asistencial. 健康方面的故意杀人。护理安全的孤儿问题。
IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2021-09-15 DOI: 10.29193/rmu.37.3.9
Carlos Vivas, H. Bagnulo
Intentional homicides committed by health workers in the course of their duties are very rare events. Its importance resides in the fact that the structural and functional weaknesses of health systems are exposed through its analysis. Moreover, their harmful effects are not limited to the victims and their families, since the reliability of the health system as a whole is damaged. This article summarizes the characteristics of these attacks, emphasizing the strategies of healthcare security that can intercept offenders.
卫生工作者在履行职责过程中故意杀人是非常罕见的事件。其重要性在于,通过其分析暴露了卫生系统的结构和功能弱点。此外,它们的有害影响不仅限于受害者及其家属,因为整个卫生系统的可靠性受到损害。本文总结了这些攻击的特征,强调了可以拦截攻击者的医疗保健安全策略。
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引用次数: 0
Influencia de la incorporación de la tomosíntesis en un centro de diagnóstico mamario.
IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2021-09-15 DOI: 10.29193/rmu.37.3.5
G. Febles, Cristina Balbiani, Graciela Vázquez
Introduction: significant technological progress has been made in the history of mammography. Recently, direct digital mammography plus tomosynthesis arrived and improved breast cancer screening.Objective: to evaluate the effects of new technology in the performance of mammography, at the Breast Diagnostic Service of the British Hospital.Method: mammography performance during 2019- 2020 was compared to that between 2010 and 2018.In 2019 the previous tehcnology was substituted by a direct digital mammogram with tomosynthesis, Hologic, Selenia Dimensions model.Results: 10.725 mammographies were done in 2019-2020. Cancer was detected in 84 cases and the cancer detection rate was 8 per 1000 persons. PPV was 35%. 45.438 mammographies were done in 2010-2018. Cancer was detected in 229 cases and the cancer detection rate was 5 per 1.000 persons. PPV was 40%. As to images, it is worth pointing out an increase in microcalcifications between 2019 and 2020, when they grew from 7% of cases to 19% of cases and distortions increased from 11% to 13%.DCIS was 4 times greater in 2019-2020 when compare to the previous period of time (17% of all detected cases).Conclusions: the integration of tomosynthesis increased 60% the cancer detection rate and the DCIS was 4 times greater.
简介:在乳房x线照相术的历史上取得了重大的技术进步。最近,直接数字乳房x线摄影加上断层合成技术的出现改善了乳腺癌筛查。目的:评价新技术对英国医院乳腺诊断部乳房x光检查性能的影响。方法:将2019- 2020年乳腺x线摄影表现与2010 - 2018年进行比较。2019年,以前的技术被直接数字乳房x光检查所取代,该检查具有断层合成、Hologic、Selenia Dimensions模型。结果:2019-2020年共进行乳房x光检查10.725例。发现84例癌症,癌症检出率为每1000人8例。PPV为35%。2010-2018年共进行了45438例乳房x光检查。发现229例癌症,癌症检出率为每1000人5例。PPV为40%。至于图像,值得指出的是,微钙化在2019年至2020年间有所增加,从7%的病例增加到19%的病例,扭曲从11%增加到13%。与前一时期相比,2019-2020年DCIS增加了4倍(占所有发现病例的17%)。结论:结合断层合成可使肿瘤检出率提高60%,DCIS提高4倍。
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引用次数: 0
Morbimortalidad asociada al Departamento de Neurocirugía del Hospital de Clínicas. Estudio longitudinal retrospectivo durante el período Abril 2017-2019. 临床医院神经外科相关发病率和死亡率。2017-2019年4月回顾性纵向研究。
IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2021-09-15 DOI: 10.29193/rmu.37.3.4
Gonzalo Bertullo, Rodrigo Moragues, Laura Lanning, V. Reyes, Agustín Oliveira, Cristian Cardozo, Rodrigo Veiga, Patricia Álvarez
Introduction: morbidity and mortality rates allow for the evaluation of the quality of care and outcome and they also make it possible to compare different healthcare centers. This is the first morbidity and mortality study in neurosurgery carried out in Uruguay.Objective: to determine the global and specific morbidity and mortality rates in the Neurosurgery Department at the Clinicas University Hospital, and to determine if mortality and morbidity are associated to surgical complications.Method: retrospective, longitudinal, observational and descriptive analysis of all patients  >15 years old that underwent a neurosurgical procedure between April 2017 and 2019. Data were obtained from patient medical records. The following variables were analyzed: age, sex, comorbidity, clinical data, diagnosis, opportunity of surgical procedure, complications, type of complication, mortality, cause of mortality, outcome and surgical time.Results: 477 patients underwent neurosurgical procedure, 72 of which were complicated surgeries. Overall mortality was 5.5% (26/477) and morbidity 15% (72/477). 36% of complicated patients died (26/72). Vascular pathology was the specific morbidity that complicated patients the most 20% (14/69). Infection was the most frequent type of complication 46% (39/84). The evolution of the disease itself and the terrain caused the death of 90% of complicated patients undergoing emergency surgery (19/21), being the latter an independent risk factor for death (p = 0.018).As to coordinated surgeries, the cause of death was associated to the surgical act (80%). Association was found between vascular pathology and morbidity and mortality (p = 0.015) and between ischemic complication and morbidity and mortality (p = 0.024). The presence of intracranial hypertension (IH) was associated with a bad outcome (p= 0.003).Conclusions: the results show a good quality of care compared to other centers. There are still aspects to correct to reduce morbidity and mortality rates.
前言:发病率和死亡率可以用来评估护理质量和结果,也可以用来比较不同的保健中心。这是乌拉圭进行的第一次神经外科发病率和死亡率研究。目的:确定临床大学医院神经外科的全球和特定发病率和死亡率,并确定死亡率和发病率是否与手术并发症有关。方法:对2017年4月至2019年4月间接受神经外科手术的所有>15岁患者进行回顾性、纵向、观察性和描述性分析。数据来自患者的医疗记录。分析以下变量:年龄、性别、合并症、临床资料、诊断、手术时机、并发症、并发症类型、死亡率、死亡原因、结局和手术时间。结果:477例患者行神经外科手术,其中72例为复杂手术。总死亡率5.5%(26/477),发病率15%(72/477)。36%的并发症患者死亡(26/72)。血管病变是并发症最多的20%(14/69)。感染是最常见的并发症类型,占46%(39/84)。疾病本身的演变和地形导致90%的急诊手术并发症患者死亡(19/21),后者是死亡的独立危险因素(p = 0.018)。在协调手术中,死亡原因与手术行为有关(80%)。血管病理与发病率和死亡率之间存在相关性(p = 0.015),缺血性并发症与发病率和死亡率之间存在相关性(p = 0.024)。颅内高压(IH)的存在与不良预后相关(p= 0.003)。结论:与其他中心相比,护理质量较好。为了降低发病率和死亡率,仍有一些方面需要纠正。
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引用次数: 0
Tratamiento con toxina botulínica en niños con parálisis cerebral espástica. 肉毒杆菌毒素治疗儿童痉挛性脑瘫。
IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2021-09-15 DOI: 10.29193/rmu.37.3.2
A. Cerisola, Maite Borderre, Facundo Carranza, Camilo Cuadro, Sofía Cures, Lucía Quintela, M. Vázquez, E. Suarez, Ligia Bacchetta
Introduction: cerebral palsy (CP) is the most common source of motor disability in children and adolescents. In 85% of cases, the prevailing motor manifestation is spasticity. Botulinum toxin Type A injections (TB-A) have been used to reduce spasticity in children with cerebral palsy (CP). There are no studies at the national level that show whether the results are comparable to those reported in literature. Objective: to determine the effect of TB-A therapy in the triceps surae along with the physical rehabilitation in children with spastic cerebral palsy (CP) during 2017-2018 at the Teleton Children ́s Rehabilitation Center, Uruguay. Method: retrospective, descriptive study of a single cohort with a longitudinal follow-up was conducted, through the review of medical records belonging to patients with CP with independent or assisted gait, who received TB-A therapy to treat sural triceps spasticity during 2017-2018. Results: 40 TB-A injection procedures were analysed. A good response was observed one month and three months after being treated with TB-A, evidencing improvement in the dorsiflexion angle between the foot and the knee in flexion and extension, improvement on the modified Ashworth spasticity scale score and, in 95% of procedures, the subjective perception of parents. The effect was observed to decrease towards 6 months after the procedure. Conclusion: application of TB-A at the Teletón Center shows positive results, comparable to those reported by international blibliography.
简介:脑瘫(CP)是儿童和青少年运动障碍最常见的来源。在85%的病例中,主要的运动表现为痉挛。A型肉毒毒素注射(TB-A)已被用于减少脑瘫(CP)患儿的痉挛。目前还没有国家层面的研究表明这些结果是否与文献报道的结果相当。目的:了解乌拉圭Teleton儿童康复中心2017-2018年痉挛型脑瘫(CP)患儿三头肌表面TB-A治疗及物理康复的效果。方法:通过回顾2017-2018年期间接受TB-A治疗腓肠三头肌痉挛的独立或辅助步态CP患者的病历,对单队列进行回顾性、描述性研究,并进行纵向随访。结果:对40例TB-A注射过程进行了分析。在接受TB-A治疗的一个月和三个月后,观察到良好的反应,证明了脚和膝盖在屈伸时的背屈角度有所改善,改进的Ashworth痉挛量表得分有所改善,并且在95%的手术中,父母的主观感知有所改善。手术后6个月观察到效果下降。结论:TB-A在Teletón中心的应用取得了积极的结果,与国际文献报道的结果相当。
{"title":"Tratamiento con toxina botulínica en niños con parálisis cerebral espástica.","authors":"A. Cerisola, Maite Borderre, Facundo Carranza, Camilo Cuadro, Sofía Cures, Lucía Quintela, M. Vázquez, E. Suarez, Ligia Bacchetta","doi":"10.29193/rmu.37.3.2","DOIUrl":"https://doi.org/10.29193/rmu.37.3.2","url":null,"abstract":"Introduction: cerebral palsy (CP) is the most common source of motor disability in children and adolescents. In 85% of cases, the prevailing motor manifestation is spasticity. Botulinum toxin Type A injections (TB-A) have been used to reduce spasticity in children with cerebral palsy (CP). There are no studies at the national level that show whether the results are comparable to those reported in literature. Objective: to determine the effect of TB-A therapy in the triceps surae along with the physical rehabilitation in children with spastic cerebral palsy (CP) during 2017-2018 at the Teleton Children ́s Rehabilitation Center, Uruguay. Method: retrospective, descriptive study of a single cohort with a longitudinal follow-up was conducted, through the review of medical records belonging to patients with CP with independent or assisted gait, who received TB-A therapy to treat sural triceps spasticity during 2017-2018. Results: 40 TB-A injection procedures were analysed. A good response was observed one month and three months after being treated with TB-A, evidencing improvement in the dorsiflexion angle between the foot and the knee in flexion and extension, improvement on the modified Ashworth spasticity scale score and, in 95% of procedures, the subjective perception of parents. The effect was observed to decrease towards 6 months after the procedure. Conclusion: application of TB-A at the Teletón Center shows positive results, comparable to those reported by international blibliography.","PeriodicalId":51931,"journal":{"name":"Revista Medica del Uruguay","volume":"57 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76465717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ESPLENECTOMÍA LAPAROSCÓPICA EN ESPLENOMAGALIA MASIVA POR LINFOMA NO HODGKIN DE ZONA MARGINAL. 边缘区非霍奇金淋巴瘤大肿块脾肿大的腹腔镜脾切除术。
IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2021-09-15 DOI: 10.29193/rmu.37.3.12
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引用次数: 0
Luxación traumática aguda de rodilla. Indicaciones del uso del fijador externo en la urgencia 急性创伤性膝关节脱位。紧急情况下使用外部固定剂的适应症
IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL Pub Date : 2021-09-15 DOI: 10.29193/rmu.37.3.7
M. Pamparato, Juan M Del Castillo, L. Francescoli
Introduction: traumatic dislocation of the knee constitutes an unusual lesion in orthopedic pathology, the diagnosis of which is often missed. This is because it occurs in the context of multiple trauma patients, and failure to diagnose it may result in a potentially fatal outcome for the life-threatening compromise of the injured limb.Objective: to perform a literature review of literature on indications for the use of the external fixator in the acute knee dislocation at the emergency room that has been available in the last twenty years.Method: we conducted a systematized search by means of electronic search engines Cochrane, Lilacs, Scielo, Pubmed, Science direct and the Timbo portal. The search included 6495 articles and according to the criteria of inclusion and exclusion 14 studies were selected.Results: the review highlights that most articles found are level of evidence IV. The use of the external fixator in the emergency room as part of the temporary stabilization and initial handling of the condition would be indicated in the following clinical scenarios: multiple trauma patients, vascular lesion, exposed dislocation, joint instability, recurrent dislocation, fracture dislocation, lesions of the extensor apparatus, morbid obesity, splint or orthosis intolerance.Conclusion: systematization and the observation of protocols when it comes to the making of decisions enables the decrease of most complications associated to trauma pathologies. Actions must be geared to stabilizing patients first and to stabilize the knee joint. The external fixator is indicated for specific clinical scenarios. However, some of these indications are still a matter of debate.
简介:外伤性膝关节脱位是骨科病理学中一种罕见的病变,其诊断常常被遗漏。这是因为它发生在多重创伤患者的背景下,如果诊断失败,可能会导致潜在的致命结果,危及受伤肢体的生命。目的:对近二十年来在急诊室使用外固定架治疗急性膝关节脱位的适应症进行文献综述。方法:通过电子搜索引擎Cochrane, Lilacs, Scielo, Pubmed, Science direct和Timbo portal进行系统搜索。检索到6495篇文献,根据纳入和排除标准选择了14篇研究。结果:该综述强调发现的大多数文章为IV级证据。在急诊室使用外固定架作为临时稳定和初步处理病情的一部分将适用于以下临床情况:多发创伤患者,血管病变,暴露脱位,关节不稳定,复发性脱位,骨折脱位,伸肌器病变,病态肥胖,夹板或矫形器不耐受。结论:在做出决定时,系统化和对方案的观察可以减少大多数与创伤病理相关的并发症。行动必须首先稳定患者和稳定膝关节。外固定架适用于特殊的临床情况。然而,其中一些迹象仍存在争议。
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引用次数: 0
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Revista Medica del Uruguay
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