{"title":"Chickenpox","authors":"Article Editorial","doi":"10.15690/rpj.v4i2.2547","DOIUrl":"https://doi.org/10.15690/rpj.v4i2.2547","url":null,"abstract":"<jats:p>.</jats:p>","PeriodicalId":52396,"journal":{"name":"Russian Journal of Pediatric Hematology and Oncology","volume":"87 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73359602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background. There are still understudied issues concerning the health indicators of children who are in conditions of conducting warfare in primary school age. Objective. The aim of the study is to evaluate comprehensive rehabilitation measures to optimize health indicators (physical, functional and mental capacity parameters) of primary school children in conditions of military conflict.Methods. An examination of 419 elementary school children was conducted in the period from March 2022 to September 2022 including. The main group: 128 children, who lived in the territory of military operations. Control group: 291 children who lived peaceful territories. The indicators (body mass index, Robinson index, vital index, strength index, V.A. Shapovalova power index and mental capacity of children according to the results of V.Ya. Anfimov correction task) were compared before the start of the developed comprehensive rehabilitation program and 6 months after the start of its implementation.Results. It was found that all elementary school children who lived in locations of military conflict had a decrease in physical and functional parameters of varying degrees of severity, as well as indicators of mental capacity. The comprehensive rehabilitation program promoted to the normalization of the studied indicators in evacuated (57/86, 56%) children in comparison with children who remained in the locations of military operations (43/70, 49%). The studied indicators had the highest recovery rates at the age of 7-8 years. The most vulnerable was a subgroup of 9-10 years old boys who permanently living in conditions of conducting warfare. The development and implementation of the comprehensive integration program using individual rehabilitation routes had an optimizing effect on the studied indicators of physical and functional conditions, as well as cognitive performance in 101 children of the main subgroups, which amounted to 78.9%.Conclusion. Under the influence of the comprehensive integration rehabilitation program, optimization of health indicators was observed in children living in locations of conducting warfare. The most pronounced effect was observed in children who left the territories of shelling as a result of evacuation to Rostov-on-Don.
{"title":"Dynamics of indicators characterizing the health of children in the territory of military conflict. The impact of rehabilitation measures: cohort study","authors":"A. M. Levchin, I. B. Ershova, A. G. Rogovtsova","doi":"10.15690/rpj.v4i2.2535","DOIUrl":"https://doi.org/10.15690/rpj.v4i2.2535","url":null,"abstract":"Background. There are still understudied issues concerning the health indicators of children who are in conditions of conducting warfare in primary school age. Objective. The aim of the study is to evaluate comprehensive rehabilitation measures to optimize health indicators (physical, functional and mental capacity parameters) of primary school children in conditions of military conflict.Methods. An examination of 419 elementary school children was conducted in the period from March 2022 to September 2022 including. The main group: 128 children, who lived in the territory of military operations. Control group: 291 children who lived peaceful territories. The indicators (body mass index, Robinson index, vital index, strength index, V.A. Shapovalova power index and mental capacity of children according to the results of V.Ya. Anfimov correction task) were compared before the start of the developed comprehensive rehabilitation program and 6 months after the start of its implementation.Results. It was found that all elementary school children who lived in locations of military conflict had a decrease in physical and functional parameters of varying degrees of severity, as well as indicators of mental capacity. The comprehensive rehabilitation program promoted to the normalization of the studied indicators in evacuated (57/86, 56%) children in comparison with children who remained in the locations of military operations (43/70, 49%). The studied indicators had the highest recovery rates at the age of 7-8 years. The most vulnerable was a subgroup of 9-10 years old boys who permanently living in conditions of conducting warfare. The development and implementation of the comprehensive integration program using individual rehabilitation routes had an optimizing effect on the studied indicators of physical and functional conditions, as well as cognitive performance in 101 children of the main subgroups, which amounted to 78.9%.Conclusion. Under the influence of the comprehensive integration rehabilitation program, optimization of health indicators was observed in children living in locations of conducting warfare. The most pronounced effect was observed in children who left the territories of shelling as a result of evacuation to Rostov-on-Don.","PeriodicalId":52396,"journal":{"name":"Russian Journal of Pediatric Hematology and Oncology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88926185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-18DOI: 10.21682/2311-1267-2023-10-1-57-67
There is no doubt that allogeneic hematopoietic stem cell transplantation (allo-HSCT) is one of the most effective treatments for many serious diseases. However, despite significant progress, allo-HSCT is still associated with a high rate of complications and mortality in the posttransplant period due to the toxicity of conditioning regimens, infectious and immune conditions. Acute complications such as endothelial injury, acute and chronic graft-versus-host disease (GVHD) remain the main causes of mortality after allo-HSCT. In our clinical case, we demonstrated an example of the development of such life-threatening complications as transplant-associated thrombotic microangiopathy and GVHD in a patient after repeated allo-HSCT, as well as the successful relief of these complications by modern therapeutic methods, including the introduction of closely related donor mesenchymal stem cells and the complement blocker eculizumab.
{"title":"Modern methods of therapy in the development of life-threatening complications in a patient after repeated allogeneic hematopoietic stem cell transplantation: review of the literature and clinical case","authors":"","doi":"10.21682/2311-1267-2023-10-1-57-67","DOIUrl":"https://doi.org/10.21682/2311-1267-2023-10-1-57-67","url":null,"abstract":"There is no doubt that allogeneic hematopoietic stem cell transplantation (allo-HSCT) is one of the most effective treatments for many serious diseases. However, despite significant progress, allo-HSCT is still associated with a high rate of complications and mortality in the posttransplant period due to the toxicity of conditioning regimens, infectious and immune conditions. Acute complications such as endothelial injury, acute and chronic graft-versus-host disease (GVHD) remain the main causes of mortality after allo-HSCT. In our clinical case, we demonstrated an example of the development of such life-threatening complications as transplant-associated thrombotic microangiopathy and GVHD in a patient after repeated allo-HSCT, as well as the successful relief of these complications by modern therapeutic methods, including the introduction of closely related donor mesenchymal stem cells and the complement blocker eculizumab.","PeriodicalId":52396,"journal":{"name":"Russian Journal of Pediatric Hematology and Oncology","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85518684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-18DOI: 10.21682/2311-1267-2023-10-1-73-80
D. Martynov, Т. S. Belysheva, Т. T. Valiev, O. A. Kapkova, E. Sharapova, A. Prokofyev, Y. Vishnevskaya, E. Mikhailova, T. R. Panferova, S. Varfolomeeva
malignant neoplasms (MNP). The frequency of PNS in MNP ranges from 1 to 20 % according to different authors. One of the manifestations of PNS is acne, which occurs against the background of malignant neoplasm due to hormonal disorders.The presented article describes a clinical case of a patient with a mixed germ cell tumor and metastases in the retroperitoneal lymph nodes. The germ cell tumor produced human beta-chorionic gonadotropin, which led to the development of acne as a PNS.Antitumor treatment (surgical removal of the tumor and polychemotherapy) normalized the levels of human beta-chorionic gonadotropin and serum testosterone, which in turn led to regression of acne without acne therapy.
{"title":"Acne disease in germ cell tumors. A brief review of the literature and a description of our own clinical observation","authors":"D. Martynov, Т. S. Belysheva, Т. T. Valiev, O. A. Kapkova, E. Sharapova, A. Prokofyev, Y. Vishnevskaya, E. Mikhailova, T. R. Panferova, S. Varfolomeeva","doi":"10.21682/2311-1267-2023-10-1-73-80","DOIUrl":"https://doi.org/10.21682/2311-1267-2023-10-1-73-80","url":null,"abstract":"malignant neoplasms (MNP). The frequency of PNS in MNP ranges from 1 to 20 % according to different authors. One of the manifestations of PNS is acne, which occurs against the background of malignant neoplasm due to hormonal disorders.The presented article describes a clinical case of a patient with a mixed germ cell tumor and metastases in the retroperitoneal lymph nodes. The germ cell tumor produced human beta-chorionic gonadotropin, which led to the development of acne as a PNS.Antitumor treatment (surgical removal of the tumor and polychemotherapy) normalized the levels of human beta-chorionic gonadotropin and serum testosterone, which in turn led to regression of acne without acne therapy.","PeriodicalId":52396,"journal":{"name":"Russian Journal of Pediatric Hematology and Oncology","volume":"107 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79045448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-18DOI: 10.21682/2311-1267-2023-10-1-68-72
D. Khestanov, M. M. Efimova, O. M. Romantsova, V. Khairullova, A. Malakhova, E. Mikhailova, A. Dzampaev, S. Varfolomeeva
Synovial sarcoma (SS) is a soft tissue tumor that occurs among a group of tumors other than rhabdomyosarcoma (RMS) in childhood and adolescence in 4 % of cases. In terms of incidence among children, SS is second only to RMS and most often occurs in young and mature patients (15–35 years), with a slight predominance in men. The localization of SS in the soft tissues of the extremities reaches 80 %; to a lesser extent, these tumors occur in the head and neck, trunk, retroperitoneal space, and joints (no more than 5 %). Cases of the appearance of SS in the mediastinum, peripheral nerves, skin and visceral organs are also described.This article presents a rare clinical case of the development of SS of the median nerve of the right shoulder in a 15-year-old patient.
{"title":"Synovial sarcoma of the median nerve of the right shoulder (case report)","authors":"D. Khestanov, M. M. Efimova, O. M. Romantsova, V. Khairullova, A. Malakhova, E. Mikhailova, A. Dzampaev, S. Varfolomeeva","doi":"10.21682/2311-1267-2023-10-1-68-72","DOIUrl":"https://doi.org/10.21682/2311-1267-2023-10-1-68-72","url":null,"abstract":"Synovial sarcoma (SS) is a soft tissue tumor that occurs among a group of tumors other than rhabdomyosarcoma (RMS) in childhood and adolescence in 4 % of cases. In terms of incidence among children, SS is second only to RMS and most often occurs in young and mature patients (15–35 years), with a slight predominance in men. The localization of SS in the soft tissues of the extremities reaches 80 %; to a lesser extent, these tumors occur in the head and neck, trunk, retroperitoneal space, and joints (no more than 5 %). Cases of the appearance of SS in the mediastinum, peripheral nerves, skin and visceral organs are also described.This article presents a rare clinical case of the development of SS of the median nerve of the right shoulder in a 15-year-old patient.","PeriodicalId":52396,"journal":{"name":"Russian Journal of Pediatric Hematology and Oncology","volume":"120 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78023220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-17DOI: 10.21682/2311-1267-2023-10-1-25-32
S. Kulyova, A. A. Abadjeva, E. Mikhailova, M. A. Kulyov, Y. G. Fedukova, R. I. Khabarova
Currently, the use high doses chemotherapy (HDC) supported by autologous peripheral blood stem cells in consolidation is a necessary therapeutic option in patients with high-risk neuroblastoma (NB). Conditioning regimens and schemes of HDC remain the subject of debate. In recent years, the evidence base of the advantages of tandem myeloablative procedures in comparison with single-transplantation has been actively accumulated in clinical practice. This article presents our own experience of tandem-transplantation with stem cell rescue in the N.N. Petrov National Medical Research Centre of Oncology (Saint-Petersburg) in four patients with initially stratified high-risk group NB; two of them were NMYC amplified. Tandem consolidation included TC ([T]hiotepa, [C]yclophosphamide) and CEM ([C]arboplatin, [E]toposide, [M]elphalan) regimens. The acceptable toxicity of the tandem-transplantation is proved.
{"title":"Tandem high-dose chemotherapy and autologous hematopoietic stem cell transplantation in pediatric patients with high-risk neuroblastoma: single-center experience","authors":"S. Kulyova, A. A. Abadjeva, E. Mikhailova, M. A. Kulyov, Y. G. Fedukova, R. I. Khabarova","doi":"10.21682/2311-1267-2023-10-1-25-32","DOIUrl":"https://doi.org/10.21682/2311-1267-2023-10-1-25-32","url":null,"abstract":"Currently, the use high doses chemotherapy (HDC) supported by autologous peripheral blood stem cells in consolidation is a necessary therapeutic option in patients with high-risk neuroblastoma (NB). Conditioning regimens and schemes of HDC remain the subject of debate. In recent years, the evidence base of the advantages of tandem myeloablative procedures in comparison with single-transplantation has been actively accumulated in clinical practice. This article presents our own experience of tandem-transplantation with stem cell rescue in the N.N. Petrov National Medical Research Centre of Oncology (Saint-Petersburg) in four patients with initially stratified high-risk group NB; two of them were NMYC amplified. Tandem consolidation included TC ([T]hiotepa, [C]yclophosphamide) and CEM ([C]arboplatin, [E]toposide, [M]elphalan) regimens. The acceptable toxicity of the tandem-transplantation is proved.","PeriodicalId":52396,"journal":{"name":"Russian Journal of Pediatric Hematology and Oncology","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76278163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-17DOI: 10.21682/2311-1267-2023-10-1-41-48
M. V. Natrusova, E. A. Burtsev, N. V. Bronina, D. S. Osipova, D. A. Evseev, E. V. Seliverstova, G. O. Bronin, M. A. Maschan, Е. V. Kumirova
Relevance. Juvenile xanthogranuloma (JXG) is the most common form of non-Langerhans cell histiocytic disorder. Cutaneous forms of the disease spontaneously regress within a few years, while systemic forms of JXG require treatment and may pose a threat to the lives of patients. Due to the lack of unified approach to the treatment of multisystem forms of JXG, the question of effective therapy tactics remains unresolved. The most common approach is to use Langerhans cell histiocytosis (LCH) treatment regimens for JXG. With the understanding of the leading role of mutations in the MEK-ERK signaling pathway in the pathogenesis of JXG, targeted therapy, BRAF- and MEK-inhibitors, are increasingly being considered in the treatment of JXG. Clinical cases. We present two cases of multisystem JXG with central nervous system (CNS) lesions. The first patient with CNS and skin lesions was treated with chemotherapy, developed for the treatment of multisystem LCH, which allowed us to obtain an effect “active disease better” (AD better). The second JXG patient with brain, lungs, bones, and adrenal gland lesions, combined targeted therapy with BRAF- and MEKinhibitors, vemurafenib and cobimetinib, resulted in a “non active disease” (NAD) effect. Conclusion. Multisystem form of JXG with CNS involvement is a rare oncological disease, the therapy of which has not been developed. With the introduction of molecular genetic profiling technology, it became possible to obtain NAD effect using targeted therapy.
{"title":"Approaches to the treatment of a multisystem form of juvenile xanthogranuloma with central nervous system lesion","authors":"M. V. Natrusova, E. A. Burtsev, N. V. Bronina, D. S. Osipova, D. A. Evseev, E. V. Seliverstova, G. O. Bronin, M. A. Maschan, Е. V. Kumirova","doi":"10.21682/2311-1267-2023-10-1-41-48","DOIUrl":"https://doi.org/10.21682/2311-1267-2023-10-1-41-48","url":null,"abstract":"Relevance. Juvenile xanthogranuloma (JXG) is the most common form of non-Langerhans cell histiocytic disorder. Cutaneous forms of the disease spontaneously regress within a few years, while systemic forms of JXG require treatment and may pose a threat to the lives of patients. Due to the lack of unified approach to the treatment of multisystem forms of JXG, the question of effective therapy tactics remains unresolved. The most common approach is to use Langerhans cell histiocytosis (LCH) treatment regimens for JXG. With the understanding of the leading role of mutations in the MEK-ERK signaling pathway in the pathogenesis of JXG, targeted therapy, BRAF- and MEK-inhibitors, are increasingly being considered in the treatment of JXG. Clinical cases. We present two cases of multisystem JXG with central nervous system (CNS) lesions. The first patient with CNS and skin lesions was treated with chemotherapy, developed for the treatment of multisystem LCH, which allowed us to obtain an effect “active disease better” (AD better). The second JXG patient with brain, lungs, bones, and adrenal gland lesions, combined targeted therapy with BRAF- and MEKinhibitors, vemurafenib and cobimetinib, resulted in a “non active disease” (NAD) effect. Conclusion. Multisystem form of JXG with CNS involvement is a rare oncological disease, the therapy of which has not been developed. With the introduction of molecular genetic profiling technology, it became possible to obtain NAD effect using targeted therapy.","PeriodicalId":52396,"journal":{"name":"Russian Journal of Pediatric Hematology and Oncology","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136244006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-17DOI: 10.21682/2311-1267-2023-10-1-33-40
T. Y. Yafoshkina, Y. Shifrin, D. Fedorova, D. B. Florinskiy, D. Evstratov, P. Zharkov
Introduction. As well as standard anticoagulants, direct oral anticoagulants (DOAC) have been approved for treatment of thromboembolism in children, recently. Several clinical trials provide promising data on efficacy and safety of DOAC in children and young adults. But further studies aimed at evaluating the efficacy and safety of these drugs in children and adolescents are still needed.The aim of the study is to evaluate the safety and effectiveness of the use DOACs in children.Materials and methods. We have retrospectively analyzed the medical records of patients (0–17 years) of from 2013 to 2022 at our tertiary care Centre and selected patients, who were treated with apixaban, rivaroxaban or dabigatran for more than 14 days. Patients with arterial thrombosis, children, who were treated with combined anticoagulant therapy and those who were unable for follow-up were excluded. We assessed the rates of bleeding and recurrent venous thromboembolism (VTE).Results. There were 67 patients, who were treated with DOAC in our center. Patients were divided into 2 groups: those, who received prophylactic anticoagulation (group 1 – 6 patients), and patients, who received DOAC therapy after venous thromboembolism (group 2 – 61 patients). The median follow-up time was 46 (25–365) days in the group 1, and 4 months (2 weeks – 36 month) in the group 2. There were no VTE episodes and 1 minor bleeding in group 1, while 1 (2 %) major, 4 (6 %) minor bleeding episodes in group 2. There were 4 (6 %) patients with recurrent VTE in group 2.Conclusion. The majority of patients in this study received rivaroxaban (79 %). We found a moderately increased recurrence rate of VTE, which could be the result of a long follow-up period, and a comparable rate of bleeding, all of which were associated with rivaroxaban therapy. In the future, of particular interest, in our opinion, are prospective studies of DOACs as primary antithrombotic prophylaxis, as well as secondary prophylaxis in the highest-risk groups, and the results of an analysis of their use in real clinical practice.
{"title":"Efficacy and safety of direct oral anticoagulants in children in real clinical practice","authors":"T. Y. Yafoshkina, Y. Shifrin, D. Fedorova, D. B. Florinskiy, D. Evstratov, P. Zharkov","doi":"10.21682/2311-1267-2023-10-1-33-40","DOIUrl":"https://doi.org/10.21682/2311-1267-2023-10-1-33-40","url":null,"abstract":"Introduction. As well as standard anticoagulants, direct oral anticoagulants (DOAC) have been approved for treatment of thromboembolism in children, recently. Several clinical trials provide promising data on efficacy and safety of DOAC in children and young adults. But further studies aimed at evaluating the efficacy and safety of these drugs in children and adolescents are still needed.The aim of the study is to evaluate the safety and effectiveness of the use DOACs in children.Materials and methods. We have retrospectively analyzed the medical records of patients (0–17 years) of from 2013 to 2022 at our tertiary care Centre and selected patients, who were treated with apixaban, rivaroxaban or dabigatran for more than 14 days. Patients with arterial thrombosis, children, who were treated with combined anticoagulant therapy and those who were unable for follow-up were excluded. We assessed the rates of bleeding and recurrent venous thromboembolism (VTE).Results. There were 67 patients, who were treated with DOAC in our center. Patients were divided into 2 groups: those, who received prophylactic anticoagulation (group 1 – 6 patients), and patients, who received DOAC therapy after venous thromboembolism (group 2 – 61 patients). The median follow-up time was 46 (25–365) days in the group 1, and 4 months (2 weeks – 36 month) in the group 2. There were no VTE episodes and 1 minor bleeding in group 1, while 1 (2 %) major, 4 (6 %) minor bleeding episodes in group 2. There were 4 (6 %) patients with recurrent VTE in group 2.Conclusion. The majority of patients in this study received rivaroxaban (79 %). We found a moderately increased recurrence rate of VTE, which could be the result of a long follow-up period, and a comparable rate of bleeding, all of which were associated with rivaroxaban therapy. In the future, of particular interest, in our opinion, are prospective studies of DOACs as primary antithrombotic prophylaxis, as well as secondary prophylaxis in the highest-risk groups, and the results of an analysis of their use in real clinical practice.","PeriodicalId":52396,"journal":{"name":"Russian Journal of Pediatric Hematology and Oncology","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78745084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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