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Morphometric study of nasal parameters in undergraduates at a medical university in central Uttar Pradesh 北方邦中部一所医科大学本科生鼻腔形态参数研究
Q4 Medicine Pub Date : 2023-07-01 DOI: 10.4103/NJCA.NJCA_89_23
V. Jasuja, Nisha Yadav, Nityanand Srivastava, Monika Srivastava, Anuj Jain
Background: Nasal morphometry is a technique which includes the study of a part, size, and shape of the human nose. The nasal index (NI), nostril shape, and philtrum shape are the parameters commonly studied. These may show variations according to regional, ethnic, and climatic differences. Hence, a study was done to calculate the NI among a subgroup and classify the nose type based on it. Also to assess the gender variations and to observe the nostril and philtrum shapes. Methodology: This was a cross-sectional study consisted of 210 undergraduate students at a medical university. The nasal height and nasal breadth were measured in centimeters with a Digital Vernier Caliper. Subsequently, the NI was calculated. Based on these nasal indices, the nose was classified into the following: leptorrhine: <70, mesorrhine: 70–84.9, and platyrrhine: >84.9. The nostril shapes (rectangular/triangular/teardrop/round) and philtrum shapes (triangular/parallel/flat/concave) were also observed. Results: The mean NI was 76.06 ± 8.614 with a range from 54.7 to 110. Mesorrhine variety was the most common type. The predominant shape of the nostrils found was rectangular, whereas the most common shape of the philtrum found was triangular. Conclusions: Nasal anthropometric measurements are a simple, reliable, and cost-effective method to study the facial characteristics among a population. These measurements provide guidelines that may play a crucial role in forensics and facial reconstructive procedures.
背景:鼻形态测量是一种研究人类鼻子的部位、大小和形状的技术。鼻指数(NI)、鼻孔形状和鼻小柱形状是常用的研究参数。这些参数可能会因地区、种族和气候差异而有所变化。因此,我们进行了一项研究,以计算一个亚群体的鼻指数,并根据该指数对鼻子类型进行分类。同时评估性别差异并观察鼻孔和鼻翼的形状。研究方法:这是一项横断面研究,由一所医科大学的 210 名本科生组成。使用数字游标卡尺测量鼻高和鼻宽,单位为厘米。随后,计算出 NI。根据这些鼻部指数,鼻子被分为以下几类:瘦鼻:84.9.此外,还观察了鼻孔形状(矩形/三角形/耳垂形/圆形)和鼻翼形状(三角形/平行/扁平/凹陷)。结果平均 NI 为 76.06 ± 8.614,范围在 54.7 至 110 之间。中鼻型是最常见的类型。鼻孔的主要形状是长方形,而咽鼓管最常见的形状是三角形。结论鼻部人体测量是研究人群面部特征的一种简单、可靠和经济有效的方法。这些测量结果可为法医和面部整形手术提供重要指导。
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引用次数: 0
A cadaveric series on urovascular anomalies 泌尿血管畸形尸体系列研究
Q4 Medicine Pub Date : 2023-07-01 DOI: 10.4103/NJCA.NJCA_78_23
Jenny Jacob, Femina Sam, A. Rajeswari, John Stephen, Vithya Thandayuthapani
Congenital anomalies of the urogenital system are a wide spectrum of variations. The multiplex embryogenesis of the kidney can lead to variations in the excretory system and vascularity to it. It poses a risk to conditions such as vesicoureteral reflux, obstruction, stenosis of one or both orifices, ureterocoele, and in surgical and radiological procedures. Vascular variations such as aberrant or accessory renal vessels can cause possible compression on the ureters and is important clinically. Hence, this case series was aimed to bring out various urovascular anomalies noticed for 2 years during dissection for 1st-year medical students. Of the four cases, accessory renal arteries were noted in two, whereas aberrant renal arteries were seen in the other two. The accessory and aberrant renal arteries had a smaller caliber when compared with the main renal arteries. Variations with a preponderance to arterial origin were seen with notable differences in the size of the kidney. When these arteries are present, the size of the kidney on that side is greater than the other side. In addition, they were also associated with other anomalies such as complete bifid ureter, incomplete rotation, retroaortic left renal vein, and abdominal aortic aneurysm. Developmental anomalies may not confine to a single anomaly but a heterogeneous deviation in a single case per se, which must be identified and explored. This might help the surgeons in transplantation procedures and endovascular interventions.
先天性泌尿生殖系统畸形的变异范围很广。肾脏的多重胚胎发育可导致排泄系统和血管的变异。这对膀胱输尿管反流、梗阻、一侧或双侧输尿管口狭窄、输尿管瘘等病症以及手术和放射治疗过程都有风险。血管变异(如异常或附属肾血管)可能会对输尿管造成压迫,这在临床上非常重要。因此,本病例系列旨在介绍两年来医科一年级学生在解剖过程中注意到的各种泌尿系血管异常。在这四例病例中,有两例发现了附属肾动脉,而另外两例则发现了异常肾动脉。与主肾动脉相比,附属肾动脉和异常肾动脉的口径较小。在肾脏大小存在明显差异的情况下,肾动脉起源的变化占多数。当这些动脉存在时,该侧肾脏的大小大于另一侧。此外,这些动脉还与其他异常有关,如输尿管完全双折、旋转不完全、左肾后静脉和腹主动脉瘤。发育异常可能并不局限于单一的异常,而是单个病例本身的异质性偏差,必须加以识别和探讨。这可能有助于外科医生进行移植手术和血管内介入治疗。
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引用次数: 0
An anomalous relationship of the maxillary artery with the mandibular nerve branches: A rare case report of two anatomical variations 上颌动脉与下颌神经分支的异常关系:两例解剖变异的罕见病例报告
Q4 Medicine Pub Date : 2023-07-01 DOI: 10.4103/NJCA.NJCA_54_23
A. Occhialini, Manasa Muppirala, Sidharth Nayak, Christopher Nguyen, Hoang Nguyen, H. Nation
The maxillary artery (MA) and mandibular nerve are important structures in the infratemporal fossa (ITF) supplying large portions of the face. During a medical dissection course, two rare anatomical variations pertaining to the MA's relationship to the mandibular nerve branches were found in three ITF. In these cases, the MA was seen to travel medial to the mandibular nerve branches. Case 1 had bilateral, asymmetric variations. On the left, the MA traveled medial to a trunk formed by the inferior alveolar and lingual nerves and lateral to the chorda tympani nerve (CTN). On the right, the MA passed lateral to the lingual and CTNs and medial to the inferior alveolar nerve. Case 2 had a unilateral variation on the left such as the variation seen on the right in Case 1. A clear understanding of MA variations has several clinical implications. This study provides a resource that may prevent complications such as bleeding, hematoma, and injury to the mandibular nerve or its branches during clinical procedures.
上颌动脉(MA)和下颌神经是颞下窝(ITF)的重要结构,供应面部大部分区域。在一次医学解剖课程中,在三个 ITF 中发现了两种罕见的解剖变异,涉及上颌动脉与下颌神经分支的关系。在这些病例中,可以看到 MA 位于下颌神经分支的内侧。病例 1 存在双侧不对称变化。在左侧,MA 穿过下牙槽神经和舌神经形成的主干的内侧和鼓室神经(CTN)的外侧。在右侧,MA 穿过舌神经和 CTN 的外侧和下牙槽神经的内侧。病例 2 左侧的单侧变异与病例 1 右侧的变异相同。清楚地了解 MA 变异具有多种临床意义。这项研究提供了一种资源,可以预防临床手术中的出血、血肿和下颌神经或其分支损伤等并发症。
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引用次数: 0
Effects of graded doses of sildenafil citrate on liver microanatomy in male albino rats 不同剂量枸橼酸西地那非对雄性白化大鼠肝脏显微解剖的影响
Q4 Medicine Pub Date : 2023-04-01 DOI: 10.4103/NJCA.NJCA_229_22
Sameena Bashir, G. Bhat, S. Khanday, L. Wani
Background: Sildenafil citrate (SC) is a vasoerectile drug used to treat impotence caused by erectile dysfunction by inhibiting phosphodiesterase type 5 enzyme. The drug is widely used and may have adverse effects on the liver as it is metabolized mainly in the liver. Therefore, the present research aimed to study the effect of graded doses of SC on the histological structure of the liver in albino rats. Methodology: The present prospective interventional experimental study was conducted on 30 albino rats. The rats were given SC in different doses and for different periods. Rats were sacrificed, and the liver was extracted and processed for histopathological examination. The slides were stained with hematoxylin and eosin and observed under a compound light microscope. Results: SC administrated in graded doses in male albino rats caused central venous congestion, sinusoidal dilatation, and fatty infiltration in the liver. These changes were more pronounced in rats that received the drug in higher doses and for a longer duration. The effects of SC on the rat liver microanatomy were dose and time dependent. Conclusion: SC is relatively safe in low doses, but at higher doses and longer duration, there can be adverse effects on the liver.
背景:枸橼酸西地那非(SC)是一种血管勃起药物,通过抑制磷酸二酯酶5型酶来治疗由勃起功能障碍引起的阳痿。该药物用途广泛,可能对肝脏产生不良影响,因为它主要在肝脏中代谢。因此,本研究旨在研究分级剂量SC对白化大鼠肝脏组织结构的影响。方法:对30只白化病大鼠进行前瞻性介入实验研究。大鼠被给予不同剂量和不同时期的SC。处死大鼠,提取肝脏并进行组织病理学检查。载玻片用苏木精和伊红染色,并在复合光学显微镜下观察。结果:雄性白化大鼠分次给药SC可引起中心静脉充血、肝窦扩张和脂肪浸润。这些变化在接受更高剂量和更长时间药物治疗的大鼠中更为明显。SC对大鼠肝脏显微解剖的影响具有剂量和时间依赖性。结论:SC在低剂量下相对安全,但在高剂量和长时间时,可能会对肝脏产生不良影响。
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引用次数: 0
Histogenesis of parotid gland in human fetuses 人胎儿腮腺的组织发生
Q4 Medicine Pub Date : 2023-04-01 DOI: 10.4103/NJCA.NJCA_31_23
D. Chakraborty, A. Devi
Background: The present study attempted to find out the histological changes of parotid gland in the developing human fetuses. Materials and Methods: Parotid glands from 60 fresh fetuses of gestational weeks ranging from 12weeks to term were studied after staining with Hematoxylene & Eosin, Masson's Trichome stain, Van Gieson's stain and Verhoeff's stains. Results: The gland of the fetus at 12 weeks composed of solid epithelial cords with occasional canalization, surrounded by loose mesenchyme. Canalization of cords was completed at 25 weeks and adult picture attained at 36 weeks. Division of the glandular parenchyma into lobes and lobules by connective tissue septa started at 17 weeks. A well formed capsule was seen around the gland at 20 weeks. A gradual decrease in intra-glandular connective tissue occurred in late gestational age. Variety of cells such as fibroblasts, mesenchymal cells, fibrocytes and lymphocytes were seen. Numerous adipocytes were found within the glandular parenchyma and around the gland. Ductal tree showed gradual differentiation, presence of cilia-like surface projections from epithelia of larger ducts were seen in 14-32 week fetuses. Conclusion: When compared with various authors, some findings of the present study followed the foot-steps of previous workers whereas some were in contrary, the most important difference being the age of full maturation of the glandular architecture. One of the unique finding being the presence of cilia-like surface projections seen in the larger ducts in 14-32 week aged fetuses.
背景:本研究试图了解发育中的人类胎儿腮腺的组织学变化。材料与方法:对60例孕周~足月新鲜胎儿的腮腺进行了苏木精和曙红染色、马森毛细胞染色、范吉逊染色和Verhoeff染色。结果:12周时,胎儿的腺体由坚固的上皮索组成,偶尔有小管化,周围有松散的间充质。脊髓管化在25周时完成,成人图像在36周时获得。腺薄壁组织在17周时开始被结缔组织隔膜分裂为裂片和小叶。20周时,腺体周围可见一个形成良好的包膜。腺内结缔组织在孕晚期逐渐减少。可见成纤维细胞、间充质细胞、纤维细胞和淋巴细胞等多种细胞。在腺体薄壁组织和腺体周围发现了大量的脂肪细胞。导管树逐渐分化,14-32周胎儿可见较大导管上皮细胞的纤毛样表面突起。结论:与不同的作者相比,本研究的一些发现遵循了以前工作人员的足迹,而有些则相反,最重要的差异是腺体结构完全成熟的年龄。其中一个独特的发现是在14-32周大的胎儿的较大导管中存在纤毛样表面突起。
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引用次数: 0
Mirror neuron: The unit of imitative mind and its clinical applicability 镜像神经元:模仿思维的单位及其临床应用
Q4 Medicine Pub Date : 2023-04-01 DOI: 10.4103/NJCA.NJCA_55_23
N. Pushpa, K. Ravi
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引用次数: 0
A cross-sectional study on item analysis of prevalidated and nonvalidated anatomy multiple-choice questions 解剖学多项选择题项目分析的横断面研究
Q4 Medicine Pub Date : 2023-04-01 DOI: 10.4103/NJCA.NJCA_9_23
V. Shenoy, Pallavi Ravi, Dane Chandy
Background: Multiple-choice questions (MCQs) are widely used tools to test knowledge. Pre- and postvalidation of the MCQs are prerequisites to maintaining the standard of the questions. Prevalidation is done by subject experts before the test. Postvalidation (item analysis) uses three indices – item difficulty index (P), item discrimination index (D), and distractor efficiency (DE). This study was done with the aim to assess the quality of MCQs used during the formative assessments using item analysis indices and to compare the indices in prevalidated and nonvalidated MCQs. Methodology: The study used two sets of MCQ tests, conducted as a part of formative assessments for phase I MBBS students in the department of anatomy. Set 1 comprised nonvalidated MCQs and set 2 comprised prevalidated MCQs. The three indices were calculated for all the questions in both sets. Results: The average P value for set 1 was 57.62 ± 21.90 and that for set 2 was 59.27 ± 20.32. Average D value for set 1 was found to be 0.23 ± 0.36 and that for set 2 was 0.29 ± 0.15. In set 1, 37.5% of the MCQs had 100% DE, whereas, in set 2, 60% of the MCQs had 100% DE. Thirty percent of the distractors were nonfunctional in set 1, but in set 2, only 16.7% of the distractors were nonfunctional. Conclusions: Study results favor prevalidation and postvalidation of MCQs to develop a good-quality MCQ bank. It is imperative to use the MCQs having moderate difficulty, good discrimination power, and with all functional distractors in any given assessment.
背景:选择题(MCQ)是一种广泛使用的测试知识的工具。MCQ的预验证和后验证是保持问题标准的先决条件。测试前由受试者专家进行预验证。后验证(项目分析)使用三个指标——项目难度指数(P)、项目辨别指数(D)和干扰物效率(DE)。本研究旨在使用项目分析指数评估形成性评估中使用的MCQ的质量,并比较预先验证和未验证的MCQ中的指数。方法:该研究使用了两组MCQ测试,作为解剖学系MBBS一期学生形成性评估的一部分。集合1包括未验证的MCQ,集合2包括预先验证的MCQs。这三个指数是为两组中的所有问题计算的。结果:第1组的平均P值为57.62±21.90,第2组为59.27±20.32。第1组的平均D值为0.23±0.36,第2组为0.29±0.15。在第1组中,37.5%的MCQ具有100%的DE,而在第2组中,60%的MCQ有100%的DE。在第1集中,30%的干扰物不起作用,但在第2集中,只有16.7%的干扰器不起作用。结论:研究结果有利于MCQ的预验证和后验证,以开发一个高质量的MCQ库。在任何给定的评估中,必须使用具有中等难度、良好辨别能力并具有所有功能干扰物的MCQ。
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引用次数: 0
Vascular anomalies in the course and branching pattern of the dorsalis pedis artery: A case report 足背动脉走行和分支模式的血管异常1例
Q4 Medicine Pub Date : 2023-04-01 DOI: 10.4103/NJCA.NJCA_33_23
A. Olonade, Mehtap Tiryakioğlu
The dorsalis pedis artery (DPA) vascularizes most of the dorsum of the foot where it provides several branches. During a scheduled examination of the lower extremities of a male cadaver, a significant deviation was observed in the course and pattern of distribution of the left DPA. The artery trifurcated from its point of origin and was found to deviate from its normal course on the superior surface of the intermediate cuneiform, talus, and navicular bones. A lack of the arcuate artery was observed, and a varied branching pattern was established among the branches of the DPA on the dorsum of the foot. Knowing the detailed anatomy of the DPA and understanding its variability is of great clinical importance to surgeons, radiologists, and orthopedists due to the usefulness of this artery in different surgical interventions relating to the foot.
足背动脉(DPA)的血管分布在足背的大部分,在那里它提供了几个分支。在对一名男性尸体的下肢进行例行检查时,观察到左侧DPA的路线和分布模式有明显的偏差。动脉从其起始点分叉,并在中间楔形骨、距骨和舟骨的上表面偏离其正常路线。观察到弓状动脉缺乏,在足背DPA分支之间建立了不同的分支模式。由于该动脉在与足部有关的不同手术干预中非常有用,因此了解DPA的详细解剖结构并了解其变异性对外科医生、放射科医生和骨科医生具有重要的临床意义。
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引用次数: 1
Cytomorphometry of normal exfoliated gingival cells: An analytical study 正常脱落牙龈细胞的细胞形态测定:一项分析研究
Q4 Medicine Pub Date : 2023-04-01 DOI: 10.4103/NJCA.NJCA_245_22
Ridhdhi Patel, R. Patel, Rashvaita Patel
Introduction: Gingiva is lined by stratified squamous epithelium. One of the most common types of carcinoma in the world is oral cancer. Gingival cancers are a common type of oral neoplasm. In order to compare normal tissue with pathological smears using exfoliative oral cytology with morphometry, a baseline must be established. A study was conducted to obtain nuclear area (NA), cytoplasmic area (CA), and N:C ratio-nuclear: Cytoplasmic ratio of exfoliated normal gingival cells and to correlate it with healthy individuals by their age and gender. Methodology: Exfoliated gingival squamous cell smears were obtained from 200 subjects (100 males, 100 females) belonging to age groups <20 years, 21–40 years, 41–60 years, and >60 years. Smears were fixed and stained by routine Hematoxylin and Eosin staining procedure. With the use of both ocular micrometer and stage micrometer different cellular parameters were measured. Student's t-test was used for statistical analysis. Results: There were significant differences in NA, CA, and N:C ratio with age regardless of gender. Different age groups of males showed significant variations (P < 0.0001) in all the above parameters. The same was true for different age groups of females. In terms of NA, CA, and N:C ratio, the difference between both genders was significant regardless of age. Conclusion: Gingival smears showed age and sex-linked changes in NA, CA, and nuclear: Cytoplasmic ratio. It might serve as a standard for these variables when comparing similar measurements based on pathologic smears of malignant or premalignant nature.
简介:牙龈为层状鳞状上皮。口腔癌是世界上最常见的癌症之一。牙龈癌是一种常见的口腔肿瘤。为了将正常组织与病理涂片进行比较,必须建立一个基线。研究了脱落的正常牙龈细胞的核面积(NA)、胞质面积(CA)和N:C比值-核与胞质比值,并与健康个体的年龄和性别进行了相关性分析。方法:从年龄在60岁的200名受试者(男性100名,女性100名)中获得脱落的牙龈鳞状细胞涂片。将涂片固定,并用常规苏木精和伊红染色法染色。用眼测微仪和台测微仪分别测量了不同的细胞参数。采用学生t检验进行统计分析。结果:NA、CA、N:C比值随年龄、性别差异均有显著性差异。不同年龄组男性在上述各项指标上差异均有统计学意义(P < 0.0001)。不同年龄段的女性也是如此。在NA、CA和N:C比值方面,无论年龄大小,性别间差异均显著。结论:牙龈涂片显示NA、CA和核质比的年龄和性别相关变化。当比较基于恶性或癌前性质的病理涂片的类似测量时,它可以作为这些变量的标准。
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引用次数: 0
Effectiveness of game-based learning: A cross-sectional study on phase 1 medical students 基于游戏的学习有效性:一项针对一期医学生的横断面研究
Q4 Medicine Pub Date : 2023-04-01 DOI: 10.4103/NJCA.NJCA_4_23
P. Natarajan, S. Subramanian, Kalaivani Amitkumar, Anissa Joseph, Nithya Venugopal
Background: In the past, teaching and learning methods mainly focused on content in knowledge rather than a learning experience. Nowadays, there has been an increased use of playful approaches to teaching and learning. Game-based learning (GBL) playfully engages with educational materials. We employed two game-based applications (Kahoot and Quizizz) and the traditional method of learning using multiple-choice questions (MCQs) and compared their efficacy in providing fun-based productive learning to medical students. Methodology: A cross-sectional study. Two hundred and fifty-two Phase 1 undergraduate medical students were included in the study. They were given three different assessment methods: paper-based MCQs, Quizizz, and Kahoot! Each method contained 10 questions. All students were encouraged to complete all three quiz methods. We conducted this study for 6 months. After 6 months, the students were given a questionnaire prepared on a Likert scale to evaluate students' perception of concentration, engagement, enjoyment, and satisfaction of students. Results: P <0.05 indicated that there was a difference in average scores between the three methods (traditional quiz method, Quizizz, and Kahoot method). 96% of the students agreed that repeated attempts of doing the Quizizz in the app led to improvement in their long-term memory. The mean score of the student is highest in Kahoot! 53% of the students stated that image-based quiz was an interesting area. 92% of students felt that the live Quizizz was fun and interesting. Conclusion: A significant number of medical students enjoyed GBL since they can interact with one another and got motivated during the live Quizizz and Kahoot sessions. At the same time, students using the traditional method of learning were neither motivated nor enjoyed and hence we can utilize these game-based tools for teaching medicine and they can be used as a formative assessment tool too.
背景:过去,教学和学习方法主要关注知识内容,而不是学习体验。如今,越来越多的人使用好玩的教学方法。基于游戏的学习(GBL)与教育材料进行了有趣的互动。我们采用了两种基于游戏的应用程序(Kahoot和Quizizz)和使用多项选择题的传统学习方法(MCQ),并比较了它们在为医学生提供基于乐趣的高效学习方面的效果。方法:横断面研究。二百五十二名一期医学本科生参与了这项研究。他们得到了三种不同的评估方法:基于纸张的MCQ、Quizizz和Kahoot!每种方法包含10个问题。鼓励所有学生完成所有三种测验方法。我们进行了6个月的研究。6个月后,学生们接受了一份用Likert量表编制的问卷调查,以评估学生对专注、参与、享受和满意度的感知。结果:P<0.05表明三种方法(传统测验法、Quizizz法和Kahoot法)的平均得分存在差异。96%的学生认为,反复尝试在应用程序中进行Quizizz可以提高他们的长期记忆。这个学生的平均分在卡霍特是最高的!53%的学生表示,基于图像的测验是一个有趣的领域。92%的学生认为现场Quizizz很有趣。结论:相当多的医学生喜欢GBL,因为他们可以在现场Quizizz和Kahoot课程中相互交流并获得动力。与此同时,使用传统学习方法的学生既没有动力,也不喜欢,因此我们可以利用这些基于游戏的工具来教授医学,它们也可以用作形成性评估工具。
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引用次数: 0
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National Journal of Clinical Anatomy
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