Background: Although reverse shoulder arthroplasty (RSA) is a popular treatment, its efficacy in patients with failed rotator cuff repair (ARCR) remains unclear. In this study, we aimed to evaluate the clinical results of RSA for following failed ARCR. We hypothesized that RSA after failed ARCR would lead to improved clinical outcomes comparable to those of RSA performed without prior surgeries.
Methods: Between January 2017 and December 2022, 143 patients underwent RSA at our institution. We included 85 patients who met the study criteria and followed them for a minimum of 2 years. The patients were divided into two groups: those who underwent RSA for failed ARCR (group A: 25 patients; mean age, 77.7 years) and those who underwent primary RSA (group B: 60 patients; mean age, 77.9 years). The University of California, Los Angeles (UCLA) scores, Japanese Orthopaedic Association (JOA) scores, range of motion (ROM), Numerical Rating Scale (NRS) scores, and complication rates were compared between the two groups.
Results: At the 2-year postoperative follow-up, both groups showed significant improvements in all items. Postoperative outcome or complication rate demonstrated no significant difference between group A and group B: UCLA scores (29.7 ± 3.9 vs 29.3 ± 3.6), JOA scores (87.4 ± 6.1 vs 87.4 ± 8.6), ROM forward elevation (129.1 ± 20.1 vs 133.9 ± 24.1), ROM external rotation (29.1 ± 12.7 vs 29.4 ± 10.7), ROM internal rotation (2.4 ± 1.0 points vs 2.3 ± 1.1 point), NRS scores (0.9 ± 1.2 vs 1.1 ± 1.3), and complication rates (4.0% vs 3.3%). Group A exhibited improvement in all items, and the results were comparable to those in group B.
Conclusions: RSA in patients with prior rotator cuff repair demonstrated similar functional outcomes and complication rates to those in patients who underwent RSA without prior surgeries. The study demonstrated that prior ARCR would not be a negative predictor. For patients who are afraid of or cannot consent to artificial joint surgery, recommending ARCR first may be an option.
背景:虽然反向肩关节置换术(RSA)是一种流行的治疗方法,但其对肩袖修复失败(ARCR)患者的疗效尚不清楚。在本研究中,我们的目的是评估RSA对后续失败的ARCR的临床结果。我们假设,与之前没有手术的RSA相比,ARCR失败后的RSA会改善临床结果。方法:2017年1月至2022年12月,143例患者在我院接受了RSA。我们纳入了85名符合研究标准的患者,并对他们进行了至少2年的随访。患者被分为两组:接受RSA治疗失败的患者(A组:25例;平均年龄77.7岁)和原发性RSA患者(B组:60例;平均年龄77.9岁)。比较两组患者加州大学洛杉矶分校(UCLA)评分、日本骨科协会(JOA)评分、活动度(ROM)、数值评定量表(NRS)评分和并发症发生率。结果:术后2年随访,两组患者各项指标均有显著改善。A组和B组的术后结果或并发症发生率无显著差异:UCLA评分(29.7±3.9 vs 29.3±3.6),JOA评分(87.4±6.1 vs 87.4±8.6),ROM前抬高(129.1±20.1 vs 133.9±24.1),ROM外旋(29.1±12.7 vs 29.4±10.7),ROM内旋(2.4±1.0 vs 2.3±1.1),NRS评分(0.9±1.2 vs 1.1±1.3),并发症发生率(4.0% vs 3.3%)。A组在所有项目上都表现出改善,结果与b组相当。结论:先前进行过肩袖修复的RSA患者的功能结局和并发症发生率与未进行过手术的RSA患者相似。研究表明,先前的ARCR不会是一个负面的预测因子。对于害怕或不同意人工关节手术的患者,首先推荐ARCR可能是一种选择。
{"title":"Clinical results of reverse shoulder arthroplasty after failed arthroscopic rotator cuff repair compared to primary cases: a case-control study.","authors":"Noriaki Shimada, Jun'ichi Inoue, Ryota Takei, Kazuo Saita, Hiroshi Inui","doi":"10.1186/s42836-025-00323-0","DOIUrl":"10.1186/s42836-025-00323-0","url":null,"abstract":"<p><strong>Background: </strong>Although reverse shoulder arthroplasty (RSA) is a popular treatment, its efficacy in patients with failed rotator cuff repair (ARCR) remains unclear. In this study, we aimed to evaluate the clinical results of RSA for following failed ARCR. We hypothesized that RSA after failed ARCR would lead to improved clinical outcomes comparable to those of RSA performed without prior surgeries.</p><p><strong>Methods: </strong>Between January 2017 and December 2022, 143 patients underwent RSA at our institution. We included 85 patients who met the study criteria and followed them for a minimum of 2 years. The patients were divided into two groups: those who underwent RSA for failed ARCR (group A: 25 patients; mean age, 77.7 years) and those who underwent primary RSA (group B: 60 patients; mean age, 77.9 years). The University of California, Los Angeles (UCLA) scores, Japanese Orthopaedic Association (JOA) scores, range of motion (ROM), Numerical Rating Scale (NRS) scores, and complication rates were compared between the two groups.</p><p><strong>Results: </strong>At the 2-year postoperative follow-up, both groups showed significant improvements in all items. Postoperative outcome or complication rate demonstrated no significant difference between group A and group B: UCLA scores (29.7 ± 3.9 vs 29.3 ± 3.6), JOA scores (87.4 ± 6.1 vs 87.4 ± 8.6), ROM forward elevation (129.1 ± 20.1 vs 133.9 ± 24.1), ROM external rotation (29.1 ± 12.7 vs 29.4 ± 10.7), ROM internal rotation (2.4 ± 1.0 points vs 2.3 ± 1.1 point), NRS scores (0.9 ± 1.2 vs 1.1 ± 1.3), and complication rates (4.0% vs 3.3%). Group A exhibited improvement in all items, and the results were comparable to those in group B.</p><p><strong>Conclusions: </strong>RSA in patients with prior rotator cuff repair demonstrated similar functional outcomes and complication rates to those in patients who underwent RSA without prior surgeries. The study demonstrated that prior ARCR would not be a negative predictor. For patients who are afraid of or cannot consent to artificial joint surgery, recommending ARCR first may be an option.</p>","PeriodicalId":52831,"journal":{"name":"Arthroplasty","volume":"7 1","pages":"38"},"PeriodicalIF":4.3,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12315408/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144762317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Inadequate gap balance during total knee arthroplasty (TKA) can result in postoperative pain, restricted range of motion, and suboptimal long-term outcomes. The sagittal alignment of the femoral and tibial components plays a pivotal role in determining both the flexion and extension gaps. This study systematically investigates how variations in femoral and tibial sagittal alignment affect knee gap dynamics during TKA, utilizing intraoperative data from a robotic-assisted surgical system.
Method: This retrospective study analyzed data from 40 robotic-assisted TKA procedures. Surgical planning data were obtained using the landmark registration process. The tibial posterior slope was fixed at 3°, while the femoral flexion angle was adjusted incrementally from 3° to 8° in 1° intervals. Medial and lateral flexion gaps were measured at each increment. To examine the effect of tibial posterior slope on knee gap dynamics, the femoral flexion angle was maintained at 3°, and the tibial posterior slope was varied from 3° to 7° in 1° increments. Medial and lateral extension and flexion gaps were recorded for each configuration.
Results: Both medial and lateral flexion gaps progressively increased as the femoral flexion angle was adjusted from 3° to 8°. Similarly, both flexion and extension gaps demonstrated a corresponding increase as the tibial posterior slope was elevated from 3° to 7°. Spearman correlation analysis showed that increasing femoral flexion and tibial slope significantly increased medial and lateral gaps (ρ > 0.99).
Conclusion: Increasing femoral flexion results in a larger flexion gap, while a higher tibial slope leads to proportional increases in both flexion and extension gaps. Future studies incorporating intraoperative validation will be crucial for refining surgical techniques and improving outcomes in TKA.
{"title":"The impact of femoral flexion angle and tibial slope on knee gap in total knee arthroplasty.","authors":"Varah Yuenyongviwat, Chirathit Anusitviwat, Tawan Intiyanaravut, Payap Payapanon, Nimit Thongpulsawasdi","doi":"10.1186/s42836-025-00321-2","DOIUrl":"10.1186/s42836-025-00321-2","url":null,"abstract":"<p><strong>Background: </strong>Inadequate gap balance during total knee arthroplasty (TKA) can result in postoperative pain, restricted range of motion, and suboptimal long-term outcomes. The sagittal alignment of the femoral and tibial components plays a pivotal role in determining both the flexion and extension gaps. This study systematically investigates how variations in femoral and tibial sagittal alignment affect knee gap dynamics during TKA, utilizing intraoperative data from a robotic-assisted surgical system.</p><p><strong>Method: </strong>This retrospective study analyzed data from 40 robotic-assisted TKA procedures. Surgical planning data were obtained using the landmark registration process. The tibial posterior slope was fixed at 3°, while the femoral flexion angle was adjusted incrementally from 3° to 8° in 1° intervals. Medial and lateral flexion gaps were measured at each increment. To examine the effect of tibial posterior slope on knee gap dynamics, the femoral flexion angle was maintained at 3°, and the tibial posterior slope was varied from 3° to 7° in 1° increments. Medial and lateral extension and flexion gaps were recorded for each configuration.</p><p><strong>Results: </strong>Both medial and lateral flexion gaps progressively increased as the femoral flexion angle was adjusted from 3° to 8°. Similarly, both flexion and extension gaps demonstrated a corresponding increase as the tibial posterior slope was elevated from 3° to 7°. Spearman correlation analysis showed that increasing femoral flexion and tibial slope significantly increased medial and lateral gaps (ρ > 0.99).</p><p><strong>Conclusion: </strong>Increasing femoral flexion results in a larger flexion gap, while a higher tibial slope leads to proportional increases in both flexion and extension gaps. Future studies incorporating intraoperative validation will be crucial for refining surgical techniques and improving outcomes in TKA.</p>","PeriodicalId":52831,"journal":{"name":"Arthroplasty","volume":"7 1","pages":"37"},"PeriodicalIF":2.3,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12232597/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144576950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-04DOI: 10.1186/s42836-025-00320-3
Fumihiro Mukasa, Tomonori Baba, Koju Hayashi, Taiji Watari, Muneaki Ishijima
Background: Recent studies have demonstrated that tranexamic acid (TXA) effectively reduces postoperative blood loss after total hip arthroplasty (THA) and is a safe treatment option. However, the anti-inflammatory effect of using TXA without dexamethasone (DEX) in THA remains unclear. In this study, we evaluated the anti-inflammatory effects, postoperative pain reduction, hidden blood loss (HBL), and postoperative complications associated with the use of TXA in THA.
Methods: This retrospective cohort study included 126 patients who underwent primary THA via a direct anterior approach (DAA) between January 1, 2023, and February 29, 2024. Patients were divided into two groups based on the administration of TXA (1000 mg IV preoperatively): Group A (with TXA) and Group B (without TXA). The postoperative inflammatory response (C-reactive protein [CRP] levels) and pain (numerical rating scale [NRS]) were assessed on postoperative days (PODs) 1, 3, and 7. HBL was assessed on PODs 3 and 7. Postoperative complications were counted based on occurrences from the postoperative period until discharge.
Results: CRP levels were significantly lower on POD 1 in Group A than in Group B (P = 0.002). Postoperative pain levels in Group A peaked later, with a significant reduction in the NRS score on POD 3, compared with that in Group B (P = 0.031). HBL in Group A was significantly reduced on PODs 3 (P < 0.001) and 7 (P = 0.013) compared to that in Group B. Postoperative complications did not differ significantly between Groups A and B.
Conclusion: TXA can effectively reduce postoperative blood loss, inflammation, and pain in patients undergoing THA without postoperative complications. Using TXA alone remains a highly effective and practical approach for improving early postoperative outcomes in patients undergoing THA.
{"title":"Effects of preoperative systemic administration of tranexamic acid alone on postoperative inflammation and pain in total hip arthroplasty: a retrospective cohort study.","authors":"Fumihiro Mukasa, Tomonori Baba, Koju Hayashi, Taiji Watari, Muneaki Ishijima","doi":"10.1186/s42836-025-00320-3","DOIUrl":"10.1186/s42836-025-00320-3","url":null,"abstract":"<p><strong>Background: </strong>Recent studies have demonstrated that tranexamic acid (TXA) effectively reduces postoperative blood loss after total hip arthroplasty (THA) and is a safe treatment option. However, the anti-inflammatory effect of using TXA without dexamethasone (DEX) in THA remains unclear. In this study, we evaluated the anti-inflammatory effects, postoperative pain reduction, hidden blood loss (HBL), and postoperative complications associated with the use of TXA in THA.</p><p><strong>Methods: </strong>This retrospective cohort study included 126 patients who underwent primary THA via a direct anterior approach (DAA) between January 1, 2023, and February 29, 2024. Patients were divided into two groups based on the administration of TXA (1000 mg IV preoperatively): Group A (with TXA) and Group B (without TXA). The postoperative inflammatory response (C-reactive protein [CRP] levels) and pain (numerical rating scale [NRS]) were assessed on postoperative days (PODs) 1, 3, and 7. HBL was assessed on PODs 3 and 7. Postoperative complications were counted based on occurrences from the postoperative period until discharge.</p><p><strong>Results: </strong>CRP levels were significantly lower on POD 1 in Group A than in Group B (P = 0.002). Postoperative pain levels in Group A peaked later, with a significant reduction in the NRS score on POD 3, compared with that in Group B (P = 0.031). HBL in Group A was significantly reduced on PODs 3 (P < 0.001) and 7 (P = 0.013) compared to that in Group B. Postoperative complications did not differ significantly between Groups A and B.</p><p><strong>Conclusion: </strong>TXA can effectively reduce postoperative blood loss, inflammation, and pain in patients undergoing THA without postoperative complications. Using TXA alone remains a highly effective and practical approach for improving early postoperative outcomes in patients undergoing THA.</p>","PeriodicalId":52831,"journal":{"name":"Arthroplasty","volume":"7 1","pages":"35"},"PeriodicalIF":2.3,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12231714/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144561948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Our surgical team has been performing bicruciate-retaining total knee arthroplasty (BCR-TKAs) with functional alignment (FA). This study aimed to investigate knee kinematics before and after FA BCR-TKA, as well as the influence of these changes on clinical outcomes.
Methods: Fifty cases of BCR-TKAs were included. Intraoperative rotational kinematics and anteroposterior translations between before (preinsertion group) and after (postinsertion group) BCR-TKA were compared. The relationship between clinical outcomes and intraoperative kinematic parameters between the two groups was evaluated.
Results: The tibial internal rotational angles of the preinsertion group were significantly larger than those of the postinsertion group at 0°, 60°, 90°, and maximum flexion angles. Anteroposterior (AP) translation of the femur center relative to the tibial center of the preinsertion group was significantly smaller than that of the postinsertion group at 60° and 90° of flexion angles. No difference was found between the two groups at 0°, 30°, and maximum flexion angle. A negative relationship was found between the difference in rotational angles at maximum flexion and knee injury, and osteoarthritis outcome score (KOOS) activity of daily living (ADL), and improvement of KOOS symptom and ADL subscale scores. A positive relationship was found between the difference in rotational angles at 0° and improvement of KOOS pain, sports, and quality of life subscale scores.
Conclusions: AP translation of the femur after BCR-TKA with respect to the tibia was similar to that of the preoperative knee. The change in rotational knee kinematics after BCR-TKA showed associations with clinical outcomes; however, the relationship remains multifactorial and should be interpreted with caution.
{"title":"Intraoperative kinematics of the bicruciate retaining TKA using functional alignment and their influence on the clinical outcomes.","authors":"Hiroshi Inui, Ryota Yamagami, Kenichi Kono, Kohei Kawaguchi, Haruhiko Nakamura, Kazuo Saita, Shuji Taketomi, Sakae Tanaka","doi":"10.1186/s42836-025-00319-w","DOIUrl":"10.1186/s42836-025-00319-w","url":null,"abstract":"<p><strong>Background: </strong>Our surgical team has been performing bicruciate-retaining total knee arthroplasty (BCR-TKAs) with functional alignment (FA). This study aimed to investigate knee kinematics before and after FA BCR-TKA, as well as the influence of these changes on clinical outcomes.</p><p><strong>Methods: </strong>Fifty cases of BCR-TKAs were included. Intraoperative rotational kinematics and anteroposterior translations between before (preinsertion group) and after (postinsertion group) BCR-TKA were compared. The relationship between clinical outcomes and intraoperative kinematic parameters between the two groups was evaluated.</p><p><strong>Results: </strong>The tibial internal rotational angles of the preinsertion group were significantly larger than those of the postinsertion group at 0°, 60°, 90°, and maximum flexion angles. Anteroposterior (AP) translation of the femur center relative to the tibial center of the preinsertion group was significantly smaller than that of the postinsertion group at 60° and 90° of flexion angles. No difference was found between the two groups at 0°, 30°, and maximum flexion angle. A negative relationship was found between the difference in rotational angles at maximum flexion and knee injury, and osteoarthritis outcome score (KOOS) activity of daily living (ADL), and improvement of KOOS symptom and ADL subscale scores. A positive relationship was found between the difference in rotational angles at 0° and improvement of KOOS pain, sports, and quality of life subscale scores.</p><p><strong>Conclusions: </strong>AP translation of the femur after BCR-TKA with respect to the tibia was similar to that of the preoperative knee. The change in rotational knee kinematics after BCR-TKA showed associations with clinical outcomes; however, the relationship remains multifactorial and should be interpreted with caution.</p>","PeriodicalId":52831,"journal":{"name":"Arthroplasty","volume":"7 1","pages":"34"},"PeriodicalIF":2.3,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12224591/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144555696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-02DOI: 10.1186/s42836-025-00318-x
Jia Yi Loh, Ming Han Lincoln Liow, Glen Purnomo, Merrill Lee, Jerry Yongqiang Chen, Hee-Nee Pang, Keng Jin Darren Tay, Seng-Jin Yeo
Background: Coronal Plane Alignment of the Knee (CPAK) phenotypes I, II, and IV can achieve favorable soft tissue balance following kinematic total knee arthroplasty (KA-TKA). Given that this classification was developed from a Caucasian population, limited studies have evaluated clinical outcomes following restricted vs unrestricted KA-TKA in South-East Asian patients, this study aimed to: (1) outline the prevalence of CPAK types in a South-East Asian population, (2) compare clinical outcomes of patients undergoing restricted versus unrestricted KA-TKA.
Methods: Prospectively collected data from 232 patients who underwent KA-TKA between 2015 and 2018 were reviewed. The prevalence of CPAK in our cohort was determined using preoperative medial proximal tibial (MPTA) and lateral distal femoral (LDFA) angles measured from long-limb radiographs. Unrestricted calipered KA-TKA targeted equal bone cuts while restricted KA-TKA utilized intraoperative navigation to restrict tibia varus to 4°. Patients were assessed preoperatively, at 6 months, and 2 years using the Knee Society Score, Oxford Knee Score, and Short-Form 36. Postoperative satisfaction and expectation fulfillment were recorded. Intra- and interclass correlation of all radiographic measurements and both parametric and non-parametric statistical analysis were used.
Results: The prevalence of CPAK in our cohort: I (47.8%), II (30.6%), III (9.1%), IV (7.8%), V (3.9%), VI (0.9%), VII (0%), VIII (0%) and IX (0%). Intra- and interclass correlation of radiographic measurements were excellent at 0.98 (95%CI: 0.95-0.99, P < 0.01). Subgroup analysis of CPAK I patients demonstrated that restricted KA-TKA had better KSS objective (P = 0.04), a higher proportion of satisfied patients (P = 0.02) at 6 months, and better OKS (P = 0.03) than unrestricted KA-TKA.
Conclusion: CPAK I was the most prevalent phenotype in an Asian population. CPAK I patients undergoing restricted KA-TKA had better functional outcomes and satisfaction rates than those who underwent unrestricted KA-TKA. Future studies should focus on evaluating outcomes of different alignment strategies to personalize treatment for Asian CPAK phenotypes.
背景:膝关节冠状面对齐(CPAK)表型I、II和IV可以在运动学全膝关节置换术(KA-TKA)后实现良好的软组织平衡。考虑到这种分类是从高加索人群中发展而来的,有限的研究评估了东南亚患者在限制性和非限制性KA-TKA后的临床结果,本研究旨在:(1)概述东南亚人群中CPAK类型的患病率,(2)比较限制性和非限制性KA-TKA患者的临床结果。方法:回顾性分析2015 - 2018年间232例KA-TKA患者的前瞻性数据。我们的队列中CPAK的患病率是通过术前长肢x线片测量的胫骨内侧近端(MPTA)和股骨外侧远端(LDFA)角度来确定的。无限制卡钳式KA-TKA的目标是相等的骨切割,而受限KA-TKA利用术中导航将胫骨内翻限制在4°。术前、术后6个月和术后2年分别使用膝关节社会评分、牛津膝关节评分和Short-Form 36对患者进行评估。记录术后满意度和预期实现情况。所有放射测量的类内和类间相关性以及参数和非参数统计分析均被使用。结果:CPAK在我们队列中的患病率:I (47.8%), II (30.6%), III (9.1%), IV (7.8%), V (3.9%), VI (0.9%), VII (0%), VIII(0%)和IX(0%)。放射学测量的类内和类间相关性为0.98 (95%CI: 0.95-0.99, P),结论:CPAK I是亚洲人群中最普遍的表型。接受限制性KA-TKA的CPAK I患者比接受无限制KA-TKA的患者有更好的功能结局和满意度。未来的研究应侧重于评估不同的对齐策略的结果,以个性化治疗亚洲CPAK表型。
{"title":"Restricted kinematic total knee arthroplasty provided better functional outcomes and higher satisfaction rates for Asians of genu varum with apex distal joint line over unrestricted kinematic total knee arthroplasty.","authors":"Jia Yi Loh, Ming Han Lincoln Liow, Glen Purnomo, Merrill Lee, Jerry Yongqiang Chen, Hee-Nee Pang, Keng Jin Darren Tay, Seng-Jin Yeo","doi":"10.1186/s42836-025-00318-x","DOIUrl":"10.1186/s42836-025-00318-x","url":null,"abstract":"<p><strong>Background: </strong>Coronal Plane Alignment of the Knee (CPAK) phenotypes I, II, and IV can achieve favorable soft tissue balance following kinematic total knee arthroplasty (KA-TKA). Given that this classification was developed from a Caucasian population, limited studies have evaluated clinical outcomes following restricted vs unrestricted KA-TKA in South-East Asian patients, this study aimed to: (1) outline the prevalence of CPAK types in a South-East Asian population, (2) compare clinical outcomes of patients undergoing restricted versus unrestricted KA-TKA.</p><p><strong>Methods: </strong>Prospectively collected data from 232 patients who underwent KA-TKA between 2015 and 2018 were reviewed. The prevalence of CPAK in our cohort was determined using preoperative medial proximal tibial (MPTA) and lateral distal femoral (LDFA) angles measured from long-limb radiographs. Unrestricted calipered KA-TKA targeted equal bone cuts while restricted KA-TKA utilized intraoperative navigation to restrict tibia varus to 4°. Patients were assessed preoperatively, at 6 months, and 2 years using the Knee Society Score, Oxford Knee Score, and Short-Form 36. Postoperative satisfaction and expectation fulfillment were recorded. Intra- and interclass correlation of all radiographic measurements and both parametric and non-parametric statistical analysis were used.</p><p><strong>Results: </strong>The prevalence of CPAK in our cohort: I (47.8%), II (30.6%), III (9.1%), IV (7.8%), V (3.9%), VI (0.9%), VII (0%), VIII (0%) and IX (0%). Intra- and interclass correlation of radiographic measurements were excellent at 0.98 (95%CI: 0.95-0.99, P < 0.01). Subgroup analysis of CPAK I patients demonstrated that restricted KA-TKA had better KSS objective (P = 0.04), a higher proportion of satisfied patients (P = 0.02) at 6 months, and better OKS (P = 0.03) than unrestricted KA-TKA.</p><p><strong>Conclusion: </strong>CPAK I was the most prevalent phenotype in an Asian population. CPAK I patients undergoing restricted KA-TKA had better functional outcomes and satisfaction rates than those who underwent unrestricted KA-TKA. Future studies should focus on evaluating outcomes of different alignment strategies to personalize treatment for Asian CPAK phenotypes.</p>","PeriodicalId":52831,"journal":{"name":"Arthroplasty","volume":"7 1","pages":"33"},"PeriodicalIF":2.3,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12220281/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144546136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-07-01DOI: 10.1186/s42836-025-00317-y
François Fauré, Cécile Batailler, Constant Foissey, Elvire Servien, Sébastien Lustig
Introduction: The choice of femoral stem design during total hip arthroplasty (THA) through the Direct Anterior Approach (DAA) is critical. Shortened stems offer potential benefits such as bone preservation and reduced stress shielding. This study aimed to compare early complications at one year of follow-up between shortened and standard stems in DAA THA.
Methods: A retrospective monocentric case-control study included patients undergoing DAA THA from 2013 to 2023. Two cohorts were analyzed: 537 THA with standard stems and 346 THA with shortened stems. Three hundred forty-three patients in each group were matched (1:1) based on age, sex, and Body Mass Index (BMI). Two independent observers assessed femoral complications at one year. Femoral stem positioning was measured.
Results: The mean follow-up was 12 ± 0.5 months. The mean age was 64.1 ± 11.7 years. The mean BMI was 26.4 ± 4.4 kg/m2. Shortened stems showed a significantly lower rate of femoral complications (1.4% vs. 5.5%, P = 0.005), particularly for the GT fractures (P = 0.006). In the shortened group, stem alignment was neutral in 69% of cases, varus in 27%, and valgus in 4%.
Conclusion: Shortened stems in DAA THA were associated with a lower rate of femoral complications, particularly fewer GT fractures. Although shortened stems were more often positioned in varus, this did not impact short-term complication rates.
Trial registration: The Advisory Committee on Research Information Processing in the Field of Health (CCTIRS) approved this study on June 4, 2015 (Study ID 15-430). Video Abstract.
导读:在全髋关节置换术(THA)中,通过直接前路(DAA)选择股骨干设计是至关重要的。短茎提供了潜在的好处,如骨骼保护和减少应力屏蔽。本研究旨在比较缩短和标准的DAA THA术后1年的早期并发症。方法:回顾性单中心病例对照研究纳入2013年至2023年接受DAA THA手术的患者。对两个队列进行了分析:537例标准柄全髋关节置换术和346例短柄全髋关节置换术。每组343名患者根据年龄、性别和身体质量指数(BMI)进行1:1匹配。两名独立观察员在一年内评估股骨并发症。测量股干定位。结果:平均随访12±0.5个月。平均年龄64.1±11.7岁。平均BMI为26.4±4.4 kg/m2。短柄的股骨并发症发生率明显较低(1.4% vs. 5.5%, P = 0.005),尤其是GT骨折(P = 0.006)。在缩短的组中,69%的病例是中性的,27%的病例是内翻,4%的病例是外翻。结论:短柄DAA THA股骨并发症发生率较低,尤其是GT骨折发生率较低。虽然短柄更常定位于内翻,但这并不影响短期并发症的发生率。试验注册:卫生领域研究信息处理咨询委员会(CCTIRS)于2015年6月4日批准了这项研究(研究ID 15-430)。视频摘要。
{"title":"Does the use of shortened stems reduce early femoral complications in total hip arthroplasty using the direct anterior approach?","authors":"François Fauré, Cécile Batailler, Constant Foissey, Elvire Servien, Sébastien Lustig","doi":"10.1186/s42836-025-00317-y","DOIUrl":"10.1186/s42836-025-00317-y","url":null,"abstract":"<p><strong>Introduction: </strong>The choice of femoral stem design during total hip arthroplasty (THA) through the Direct Anterior Approach (DAA) is critical. Shortened stems offer potential benefits such as bone preservation and reduced stress shielding. This study aimed to compare early complications at one year of follow-up between shortened and standard stems in DAA THA.</p><p><strong>Methods: </strong>A retrospective monocentric case-control study included patients undergoing DAA THA from 2013 to 2023. Two cohorts were analyzed: 537 THA with standard stems and 346 THA with shortened stems. Three hundred forty-three patients in each group were matched (1:1) based on age, sex, and Body Mass Index (BMI). Two independent observers assessed femoral complications at one year. Femoral stem positioning was measured.</p><p><strong>Results: </strong>The mean follow-up was 12 ± 0.5 months. The mean age was 64.1 ± 11.7 years. The mean BMI was 26.4 ± 4.4 kg/m<sup>2</sup>. Shortened stems showed a significantly lower rate of femoral complications (1.4% vs. 5.5%, P = 0.005), particularly for the GT fractures (P = 0.006). In the shortened group, stem alignment was neutral in 69% of cases, varus in 27%, and valgus in 4%.</p><p><strong>Conclusion: </strong>Shortened stems in DAA THA were associated with a lower rate of femoral complications, particularly fewer GT fractures. Although shortened stems were more often positioned in varus, this did not impact short-term complication rates.</p><p><strong>Trial registration: </strong>The Advisory Committee on Research Information Processing in the Field of Health (CCTIRS) approved this study on June 4, 2015 (Study ID 15-430). Video Abstract.</p>","PeriodicalId":52831,"journal":{"name":"Arthroplasty","volume":"7 1","pages":"32"},"PeriodicalIF":4.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12211780/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144531033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-06-25DOI: 10.1186/s42836-025-00312-3
Hao Tang, Yixin Zhou, Baojun Mai, Binjie Zhu, Ping Chen, Yujia Fu, Guangzhi Wang
Background: Intraoperative measurement of component orientation represents a basis for optimizing outcomes after total hip arthroplasty (THA). Although the use of computer navigation systems in THA has improved the accuracy of component positioning, they have not gained widespread popularity due to their complexity, time demands, and time-consuming protocols.
Methods: We developed an Inertial Measurement Unit-based Hip Smart Trial system (IMUHST) to assist with intra-operative monitoring of hip posture. An in vitro validation experiment was conducted using a sawbones with a three-dimensional (3D) measurement model as the reference standard.
Results: The absolute mean error, Bland-Altman analysis, and Intra-class Correlation Coefficient revealed that the accuracy and precision of this system meet the threshold for clinical application.
Conclusions: In conclusion, this in vitro validation demonstrates that the IMUHST system provides accurate component orientation measurements while eliminating the cost and complexity of optical navigation, offering a practical solution for widespread adoption. Video Abstract.
{"title":"Component orientation measurements in total hip arthroplasty using an inertial measurement unit-based smart trial system.","authors":"Hao Tang, Yixin Zhou, Baojun Mai, Binjie Zhu, Ping Chen, Yujia Fu, Guangzhi Wang","doi":"10.1186/s42836-025-00312-3","DOIUrl":"10.1186/s42836-025-00312-3","url":null,"abstract":"<p><strong>Background: </strong>Intraoperative measurement of component orientation represents a basis for optimizing outcomes after total hip arthroplasty (THA). Although the use of computer navigation systems in THA has improved the accuracy of component positioning, they have not gained widespread popularity due to their complexity, time demands, and time-consuming protocols.</p><p><strong>Methods: </strong>We developed an Inertial Measurement Unit-based Hip Smart Trial system (IMUHST) to assist with intra-operative monitoring of hip posture. An in vitro validation experiment was conducted using a sawbones with a three-dimensional (3D) measurement model as the reference standard.</p><p><strong>Results: </strong>The absolute mean error, Bland-Altman analysis, and Intra-class Correlation Coefficient revealed that the accuracy and precision of this system meet the threshold for clinical application.</p><p><strong>Conclusions: </strong>In conclusion, this in vitro validation demonstrates that the IMUHST system provides accurate component orientation measurements while eliminating the cost and complexity of optical navigation, offering a practical solution for widespread adoption. Video Abstract.</p>","PeriodicalId":52831,"journal":{"name":"Arthroplasty","volume":"7 1","pages":"36"},"PeriodicalIF":2.3,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188666/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144499121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-06-09DOI: 10.1186/s42836-025-00316-z
Guanghui Zhao, Chengyuan Ma, Jianbing Ma, Jianpeng Wang
Background: While same-day discharge models for knee arthroplasty have gained significant traction in China's evolving healthcare landscape, patient perspectives on ambulatory surgical pathways remain underexplored. This qualitative study addresses a critical gap in the literature by systematically assessing patient experiences and perceptions regarding knee arthroplasty within China's emerging ambulatory care framework.
Methods: A prospective cohort of 195 consecutive patients scheduled for primary knee arthroplasty at a tertiary orthopedic referral center underwent structured data collection through the WenJuanXing platform between January 1 and June 1, 2024. This cross-sectional survey employed an anonymous voluntary survey instrument administered at two critical timepoints: 1) prior to any clinical discussions regarding postoperative care pathways, and 2) before initiation of standardized preoperative education protocols.
Results: In total, 188 participants (96%, 188/195) completed the survey. Of them, 70% were female and 84% were 60 years or older. While 68% were familiar with ambulatory surgery, awareness did not significantly differ by age (P = 0.64), sex (P = 0.19), occupation (P = 0.42), location (P = 0.55), or education level (P = 0.81). Interestingly, only 8 patients anticipated discharge within 24 h post-surgery, with most (71.8%) expecting a 3-day or more stay. However, if postoperative care was assured, 66% expressed comfort with same-day or 24-h discharge. 93% considered ambulatory knee arthroplasty suitable, and 71.8% believed it would yield superior outcomes through quicker recovery and reduced complications, infections, and pain. Despite this optimism, only 45% were willing to endure longer waits, and a third were open to paying more or traveling farther for ambulatory knee arthroplasty.
Conclusion: The study reveals that most Chinese patients initially want ≥ 3-day stays but may accept 24-h discharge for knee arthroplasty. One-third are unaware of ambulatory knee arthroplasty, so more education is needed as procedures rise.
{"title":"Patient perceptions regarding ambulatory knee arthroplasties in China.","authors":"Guanghui Zhao, Chengyuan Ma, Jianbing Ma, Jianpeng Wang","doi":"10.1186/s42836-025-00316-z","DOIUrl":"10.1186/s42836-025-00316-z","url":null,"abstract":"<p><strong>Background: </strong>While same-day discharge models for knee arthroplasty have gained significant traction in China's evolving healthcare landscape, patient perspectives on ambulatory surgical pathways remain underexplored. This qualitative study addresses a critical gap in the literature by systematically assessing patient experiences and perceptions regarding knee arthroplasty within China's emerging ambulatory care framework.</p><p><strong>Methods: </strong>A prospective cohort of 195 consecutive patients scheduled for primary knee arthroplasty at a tertiary orthopedic referral center underwent structured data collection through the WenJuanXing platform between January 1 and June 1, 2024. This cross-sectional survey employed an anonymous voluntary survey instrument administered at two critical timepoints: 1) prior to any clinical discussions regarding postoperative care pathways, and 2) before initiation of standardized preoperative education protocols.</p><p><strong>Results: </strong>In total, 188 participants (96%, 188/195) completed the survey. Of them, 70% were female and 84% were 60 years or older. While 68% were familiar with ambulatory surgery, awareness did not significantly differ by age (P = 0.64), sex (P = 0.19), occupation (P = 0.42), location (P = 0.55), or education level (P = 0.81). Interestingly, only 8 patients anticipated discharge within 24 h post-surgery, with most (71.8%) expecting a 3-day or more stay. However, if postoperative care was assured, 66% expressed comfort with same-day or 24-h discharge. 93% considered ambulatory knee arthroplasty suitable, and 71.8% believed it would yield superior outcomes through quicker recovery and reduced complications, infections, and pain. Despite this optimism, only 45% were willing to endure longer waits, and a third were open to paying more or traveling farther for ambulatory knee arthroplasty.</p><p><strong>Conclusion: </strong>The study reveals that most Chinese patients initially want ≥ 3-day stays but may accept 24-h discharge for knee arthroplasty. One-third are unaware of ambulatory knee arthroplasty, so more education is needed as procedures rise.</p>","PeriodicalId":52831,"journal":{"name":"Arthroplasty","volume":"7 1","pages":"28"},"PeriodicalIF":2.3,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12147369/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144250778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-06-06DOI: 10.1186/s42836-025-00315-0
Otis C van Varsseveld, Floris V Raasveld, Wen-Chih Liu, Justin McCarty, Caroline A Hundepool, J Michiel Zuidam, Ian L Valerio, Kyle R Eberlin
Background: Neuropathic pain, weakness, and/or numbness can complicate partial or total knee arthroplasty (KA). This study evaluates peripheral nerve surgery following KA and proposes a treatment algorithm.
Methods: Patients who underwent peripheral nerve surgery for neuropathic symptoms (neuropathic pain and/or motor dysfunction) following KA between 2012-2024 (≥ 3-month follow-up) were included. Demographics, comorbidities, and type of treatment were collected, and a cross-sectional survey assessed satisfaction (Patient Global Impression of Change, PGIC) and quality of life (EuroQol-5-Dimension-5-Level, EQ-5D-5L).
Results: Twenty-seven lower extremities treated in 26 patients with a median age of 67.0 years (IQR: 58.0-71.8) were included. Surgical indications included neuropathic pain (n = 24/27, 88.9%), foot drop (n = 1/27, 3.7%), or both (n = 2/27, 7.4%). Median time between KA and nerve surgery was 29.5 months (IQR: 12.5-71.0). Procedures included saphenous or infrapatellar branch neurectomy with active management of the nerve ending (targeted muscle reinnervation (TMR) or regenerative peripheral nerve interface (RPNI)) (48.1%, n = 13), nerve decompression (40.7%, n = 11), or a combination of the two (11.1%, n = 3). Twenty-one patients (80.8%, 22 extremities) completed the survey with a median follow-up of 1.9 years (IQR: 1.1-4.2). Improvement (PGIC) was reported in 21 extremities (95.5%), the mean EQ-5D-5L index was 0.854 (± 0.102) (US general population: 0.851 (± 0.205)).
Conclusion: Peripheral nerve surgery is beneficial for patients with neuropathic pain, numbness, and/or weakness following KA. We recommend common peroneal nerve decompression for lateral knee pain and/or foot drop, active saphenous nerve management with TMR or RPNI for medial knee pain, or a combination of the two based on the clinical scenario. These findings may aid in the decision-making process for patients with neuropathic pain following KA and warrant further validation in larger, prospective studies.
{"title":"Surgical management of peripheral nerve symptoms following knee arthroplasty.","authors":"Otis C van Varsseveld, Floris V Raasveld, Wen-Chih Liu, Justin McCarty, Caroline A Hundepool, J Michiel Zuidam, Ian L Valerio, Kyle R Eberlin","doi":"10.1186/s42836-025-00315-0","DOIUrl":"10.1186/s42836-025-00315-0","url":null,"abstract":"<p><strong>Background: </strong>Neuropathic pain, weakness, and/or numbness can complicate partial or total knee arthroplasty (KA). This study evaluates peripheral nerve surgery following KA and proposes a treatment algorithm.</p><p><strong>Methods: </strong>Patients who underwent peripheral nerve surgery for neuropathic symptoms (neuropathic pain and/or motor dysfunction) following KA between 2012-2024 (≥ 3-month follow-up) were included. Demographics, comorbidities, and type of treatment were collected, and a cross-sectional survey assessed satisfaction (Patient Global Impression of Change, PGIC) and quality of life (EuroQol-5-Dimension-5-Level, EQ-5D-5L).</p><p><strong>Results: </strong>Twenty-seven lower extremities treated in 26 patients with a median age of 67.0 years (IQR: 58.0-71.8) were included. Surgical indications included neuropathic pain (n = 24/27, 88.9%), foot drop (n = 1/27, 3.7%), or both (n = 2/27, 7.4%). Median time between KA and nerve surgery was 29.5 months (IQR: 12.5-71.0). Procedures included saphenous or infrapatellar branch neurectomy with active management of the nerve ending (targeted muscle reinnervation (TMR) or regenerative peripheral nerve interface (RPNI)) (48.1%, n = 13), nerve decompression (40.7%, n = 11), or a combination of the two (11.1%, n = 3). Twenty-one patients (80.8%, 22 extremities) completed the survey with a median follow-up of 1.9 years (IQR: 1.1-4.2). Improvement (PGIC) was reported in 21 extremities (95.5%), the mean EQ-5D-5L index was 0.854 (± 0.102) (US general population: 0.851 (± 0.205)).</p><p><strong>Conclusion: </strong>Peripheral nerve surgery is beneficial for patients with neuropathic pain, numbness, and/or weakness following KA. We recommend common peroneal nerve decompression for lateral knee pain and/or foot drop, active saphenous nerve management with TMR or RPNI for medial knee pain, or a combination of the two based on the clinical scenario. These findings may aid in the decision-making process for patients with neuropathic pain following KA and warrant further validation in larger, prospective studies.</p>","PeriodicalId":52831,"journal":{"name":"Arthroplasty","volume":"7 1","pages":"27"},"PeriodicalIF":2.3,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12142898/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144235944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-06-05DOI: 10.1186/s42836-025-00314-1
Benjamin Schlossmacher, Elena Strasser, Vincent Lallinger, Florian Pohlig, Ruediger von Eisenhart-Rothe, Igor Lazic
Background and purpose: Periprosthetic joint infection (PJI) is a devastating but rare complication. Its incidence ranges between 1%-2% in primary arthroplasties. However, infection rates are much higher in megaprostheses (15%-43%). Revision of megaprostheses (MP) is a highly complex procedure associated with massive bone loss, so that implant retention occurs as a viable initial therapy option even in chronic infections. Unfortunately, literature regarding therapy strategies and outcome reports for PJI in MP is scarce. Reinfection rates are reported to be between 22 and 58%. We therefore proposed the following questions: What is the overall outcome of PJI in MP in our cohort, and are there significant differences in infection-free survival between various surgical strategies?
Methods: In this retrospective cohort study, 50 cases of PJI in MP treated from 2010 to 2022 were identified. The median (IQR) age was 70.5 (16.3) years. Mean follow-up was 19.0 months. Treatment outcome was categorized following international consensus criteria.
Results: Overall infection-free implant survival was 42.0%. 7 patients died in direct association with the ongoing PJI, and 7 had to undergo amputation. Two-stage revision had the highest success rate of 71.4% (5/7), followed by multi-stage surgery (57.1%; 4/7), DAIR (38.7%; 12/31), and single-stage revision (0%; 0/5) (P = 0.009). Overall, treatment success rates following DAIR were 55.6% (10/18) for acute and 15.4% (2/13) for chronic infections (P = 0.027). The most common pathogens were coagulase-negative Staphylococci (42.0%; 21/50) and Staphylococcus aureus (34.0%; 17/50). Gram-negative pathogens accounted for 16.0% (8/50).
Conclusions: PJI in MP remains a devastating complication with low success rates. Two-stage revision is the most promising treatment option, but it requires patients to be able to cope with the burden of multiple surgeries. DAIR cannot be recommended as a definitive treatment for chronic cases (15% success rate) and should be questioned in acute cases (56% success rate), as infection eradication is rare. DAIR can be considered a low-impact surgery for infection control if more extensive surgery is not viable. Video Abstract.
背景与目的:假体周围关节感染(PJI)是一种严重但罕见的并发症。原发性关节置换术的发病率在1%-2%之间。然而,大型假体的感染率要高得多(15%-43%)。大型假体修复(MP)是一个高度复杂的过程,与大量骨质流失有关,因此即使在慢性感染中,种植体保留也是一种可行的初始治疗选择。不幸的是,关于PJI在MP中的治疗策略和结果报告的文献很少。据报道,再感染率在22%至58%之间。因此,我们提出了以下问题:在我们的队列中,PJI在MP中的总体结果是什么?不同手术策略在无感染生存方面是否存在显著差异?方法:回顾性队列研究,选取2010年至2022年治疗的50例MP PJI患者。中位(IQR)年龄为70.5(16.3)岁。平均随访19.0个月。治疗结果按照国际共识标准进行分类。结果:总体无感染种植体成活率为42.0%。7例患者死于正在进行的PJI直接相关,7例患者不得不截肢。两期翻修成功率最高,为71.4%(5/7),其次为多期手术(57.1%);4/7), air (38.7%;12/31),单阶段修正(0%;0/5) (p = 0.009)。总体而言,DAIR治疗急性感染的成功率为55.6%(10/18),慢性感染的成功率为15.4% (2/13)(P = 0.027)。最常见的病原菌为凝固酶阴性葡萄球菌(42.0%);21/50)和金黄色葡萄球菌(34.0%;17/50)。革兰氏阴性致病菌占16.0%(8/50)。结论:PJI在MP中仍然是一个低成功率的破坏性并发症。两阶段修复是最有希望的治疗选择,但它要求患者能够承受多次手术的负担。不能推荐DAIR作为慢性病例(15%的成功率)的最终治疗方法,对于急性病例(56%的成功率)也应提出质疑,因为感染根除是罕见的。如果不能进行更广泛的手术,DAIR可以被认为是一种低影响的感染控制手术。视频摘要。
{"title":"Periprosthetic joint infection of megaprostheses for oncologic and non-oncologic indications-IMPLANT retention or removal? A retrospective cohort study of 50 cases.","authors":"Benjamin Schlossmacher, Elena Strasser, Vincent Lallinger, Florian Pohlig, Ruediger von Eisenhart-Rothe, Igor Lazic","doi":"10.1186/s42836-025-00314-1","DOIUrl":"10.1186/s42836-025-00314-1","url":null,"abstract":"<p><strong>Background and purpose: </strong>Periprosthetic joint infection (PJI) is a devastating but rare complication. Its incidence ranges between 1%-2% in primary arthroplasties. However, infection rates are much higher in megaprostheses (15%-43%). Revision of megaprostheses (MP) is a highly complex procedure associated with massive bone loss, so that implant retention occurs as a viable initial therapy option even in chronic infections. Unfortunately, literature regarding therapy strategies and outcome reports for PJI in MP is scarce. Reinfection rates are reported to be between 22 and 58%. We therefore proposed the following questions: What is the overall outcome of PJI in MP in our cohort, and are there significant differences in infection-free survival between various surgical strategies?</p><p><strong>Methods: </strong>In this retrospective cohort study, 50 cases of PJI in MP treated from 2010 to 2022 were identified. The median (IQR) age was 70.5 (16.3) years. Mean follow-up was 19.0 months. Treatment outcome was categorized following international consensus criteria.</p><p><strong>Results: </strong>Overall infection-free implant survival was 42.0%. 7 patients died in direct association with the ongoing PJI, and 7 had to undergo amputation. Two-stage revision had the highest success rate of 71.4% (5/7), followed by multi-stage surgery (57.1%; 4/7), DAIR (38.7%; 12/31), and single-stage revision (0%; 0/5) (P = 0.009). Overall, treatment success rates following DAIR were 55.6% (10/18) for acute and 15.4% (2/13) for chronic infections (P = 0.027). The most common pathogens were coagulase-negative Staphylococci (42.0%; 21/50) and Staphylococcus aureus (34.0%; 17/50). Gram-negative pathogens accounted for 16.0% (8/50).</p><p><strong>Conclusions: </strong>PJI in MP remains a devastating complication with low success rates. Two-stage revision is the most promising treatment option, but it requires patients to be able to cope with the burden of multiple surgeries. DAIR cannot be recommended as a definitive treatment for chronic cases (15% success rate) and should be questioned in acute cases (56% success rate), as infection eradication is rare. DAIR can be considered a low-impact surgery for infection control if more extensive surgery is not viable. Video Abstract.</p>","PeriodicalId":52831,"journal":{"name":"Arthroplasty","volume":"7 1","pages":"30"},"PeriodicalIF":2.3,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12139102/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144227598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}